LOCUS       gnlProkkaIDGPNNPL_62   13572 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IDGPNNPL_62.
ACCESSION   gnlProkkaIDGPNNPL_62
VERSION     gnlProkkaIDGPNNPL_62
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 23:31:36
            Original ID  :: gnl|Prokka|IDGPNNPL_62
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13572
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13572
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3844:4111]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3845..4111
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..13572
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13572
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             24..935
                     /locus_tag="ctg62_1"
                     /transl_table=11
                     /translation="MKPTLFLLAAGMGSRYGGLKQLDGLGPNGETIMDYSIYDAINAGF
                     GKLVFVIRKDFEQDFRDKIISKYEGHIPCELVFQSIDDLPEGFTCPEGRTKPWGTNHAV
                     MMGADVIKEPFAVINCDDFYGRDSFQVMGKFLAALPEGSKNVYSMVGFRIGNTLSESGT
                     VSRGLCGTDANNLLTSVVERTKIQRMDGEVKYIDDNGEWTATPETTPVSMNFWGFTPDY
                     FAYSAEFFKSFLSDPKNMENLKSEFFIPLMVDKLINDGTATCEVLDTTSKWFGVTYPED
                     RQSVVDKIQALVDAGEYPAKLF"
     CDS             complement(980..2650)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 275.5; E-value:
                     1.5e-83)"
                     /gene_kind="transport"
                     /locus_tag="ctg62_2"
                     /transl_table=11
                     /translation="MKKQQKDKKVKKDRREKLRYIREVSAEQRGRILLSCLTGILGVAF
                     ALAFIYATKRVIDTATGITDDNLTHVAVLTVVLLTAQLLCGAADTWISTRMQIETGNAL
                     RHRLFSRLLQSRWNELERFHTGDVVNRVEQDTAAIVTLLTSSVPAFIVTSIQLLAAFLF
                     FYFLDPSLPWLIVAILPVFLLGSRFYMRRMKRYTHDIRNSDGRIQSVIQESLQHRIVIK
                     TLEQGERHLDKLDDLQDMLHSQVMGRTRFSLSAHMLVALAFSGGYLTAFLWGAVHLSAG
                     CITFGTMTAFLQLVGKVQRPVLDLSRLIPSVVNALTAIDRLLELERLPAEADGDSIFLA
                     STPELELKDVTFGYTPDDRPVFSRFSCRFPAGSCIAVVGETGKGKTTLIRLLLALATPQ
                     EGQILLIPAKHPLETSHTVSPQTRKNFVYVPQGNTLFSGTIRDNLLMGNPQASEEAIYQ
                     ALQTATADFVFHLPDGVDSPLSERGGGLSEGQAQRIAIARALLRPGNILLLDEATSALD
                     PDTERLLIKNLRRDCAGKTCIFVTHHPAVAEACESIVRL"
     CDS             complement(2673..3836)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg62_3"
                     /sec_met_domain="NTP_transf_5 (E-value: 9.8e-47, bitscore:
                     149.3, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQHAFFSLVRSGLWGTPADRQLFRSVSPDDWETVYRMANSQALLA
                     LTFDGISSLPAELRPPRALYLKWAARTAQIEQANKRLNQLLPELNTLYREAGLHPVLLK
                     GQGIGTNYRTPLHRQCGDIDIYLGKQGQPIANRLLLQQGAIVEGEASDKHASYSLKGVH
                     IENHRIILRLNSPLANRHFQQIIRKWYPQETDYALFSETGKEDSKAVSIAIPPATFNAL
                     YIFLHAFVHFLNSGIGLRQLCDWTCLLANRHKEIDATTLLRQLQDLGLLHAAQAFGYIA
                     VTRLGLPANRLPFPLEGTKQIGEQLLEDILSTGNFGQHDNRIKPRPKGYWAGKWYTFCR
                     ATRRCNELRQFAPYEALWYPVTLIGGTIAIQINRLKGVKDKKARTKK"
     CDS             complement(3845..4111)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg62_4"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1e-13,
                     bitscore: 41.0, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 4.8e-16, bitscore: 48.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKQGFILHRIGDDYIIMQDGSSNVDFSKVISLNQTSAMLWQEI
                     ENKEFDTDSVTEALTSRYDVDNESARRDAQKFIDSLDREGIIE"
     CDS             complement(4124..4564)
                     /locus_tag="ctg62_5"
                     /transl_table=11
                     /translation="MKKSIPNEILLPEVARLIKEGHTVTITVRGNSMNPFLVDRRDRVT
                     LGDFTTEQLQPGVAVLARDLTERIVFHRIIRRNGNILILQGDGNLAQTEETDIGRVMGV
                     MTEAMRKDKRYTADGKVWKLYSYWWMKLNPARRWLLALFRRI"
     CDS             complement(4591..5517)
                     /locus_tag="ctg62_6"
                     /transl_table=11
                     /translation="MRIQILDYQVGPHTFRMVKPSDFNIFKALPSLIPFITTIDTTQKV
                     IFETEIDDDETATKRTIAKTPDDICFNWEDADCIIRPLPHSSHLVSITPRKSGKNYWME
                     CNDNFRQCFIHLPACRTETPAPENETNFVLNNFLMMLYAFNAARHHTLLMHASVVATET
                     GKGYLFLGKSGTGKSTHTGLWLQQFSDCHLLNDDNPIVHVDSLGKQATVFGSPWSGKTP
                     CYRKESMTVGAFVRLEQAPQNEIEQERAAHAFATLLPSCSCLKQNKEIYNAIVTTVTEL
                     ATLAPVYHLKCLPDREATELCRKTVEG"
     CDS             complement(5764..9342)
                     /locus_tag="ctg62_7"
                     /transl_table=11
                     /translation="MMKLRNLMQVACMATAALTAFSCSQEEFENSGWKGNITVNATFEG
                     AGTDTRTTVNDEYKILWQDTDALGLFCSNAESNYSNTKLEYASGAGQTSATFNGSKPSG
                     ETAVFSIYPYQQNMSVSGNTLTMTLPATLTNYNGSSNGPMYAKVTNPDNLSALSFKHMA
                     AMIKLTVNKIPAEATTFKIIASNNIAGTCTVDLTAADPILAVTSDESKEITASFTASAD
                     IKSRNFYIPLPTGTYSSITAQLTNGSDKVYFTKTLNDKILGRRDILVVPPLDCVVVEAT
                     TPSALSTALADSKNLPQEAPTAATVTDIAVSGSFNTTSGSNDGIAIPVLQNSDINLAFN
                     TAPTTSTSAPLKLTDKTNTSVSTPAATATNSVSLAVPETTAEQEAPSVAITMPSTTVTL
                     AAVGNKATYNEVTATTAQQTLIINAGVTVKKLTVKGGNLKIYGKVEQLVHDAGNTTIYI
                     IKGTEASLPATIDSKFVVQSDVAVLKTAFANGEDFKLSADADITGQSVSVPAGKSVVLD
                     LNGYTLTADNSATGKIIVLGKMTLKDSSTEKKGKIVASQDYTAASYNGSLIEIAGEDAS
                     MTMESGNISAVRKTPNSNGQYGVGVTDGGDFTMTGGKIEAGWFAVAGNGNYKTQNSIIN
                     ITDGELISTADYAVYLPQSGTTTISGGKVYGAAGGVCIQRGTLNVEGTALITSKGTGST
                     GNWGDGTGGLDCAAINVSGAYGIATVNIKGGTLIAEAKSLITEGTTYTPVINVTGGTFS
                     DPSALKYMKTNANVNIKLTADKTCPGFKTTSGQTLTMDLGGKILTLADPTVGSTGTETN
                     SCQLLEGSNVTFKNGTLKSDNNKIMIQNYCNLTLDNMTVEDTNAQYVVSNNCGNISINN
                     TTINAGSNANQFAFDVCGYAKYTAGVTVTVSGTSVINGKVEISKSAGNTEPMKLNITGG
                     TFNGDLKVDASVGTENAKSIISVSGGTFSDPSVLKYMATNATVDIKLLSNINIAKTELA
                     TGYILNAANATANLNLNGHDIINSSETADATPFTQIFTVQNGTLNISGNGNVKCDASAT
                     AKDDGYRMVIEARGHGTVNIHGGSYYNTQKLNTQIDLIYARENGKINIYGGTFESGKYG
                     TPNNDTDGRYWVLNLKNTDKNTASIQVSGGTFINFNPANPNMDDNESYLVTGYEVTRDG
                     SVYTAAHKVNDGRKEYIVGPTSQENR"
     CDS             complement(9356..9571)
                     /locus_tag="ctg62_8"
                     /transl_table=11
                     /translation="MKQNTPDGREAYITPSIEVIKMENEGVIATSGEPYHPITRSYSGS
                     TSTHSYNSASSSDLEDLINDILTVEN"
     CDS             9620..9793
                     /locus_tag="ctg62_9"
                     /transl_table=11
                     /translation="MFVYPLFRPSHCPFPGYTTVTHVVCVYTIPPDGRKPYKHRREHPC
                     CYLQGNFQSCEV"
     CDS             complement(9937..10263)
                     /locus_tag="ctg62_10"
                     /transl_table=11
                     /translation="MKNCYGIDFRSWHKELRTREKTKQPPCKLPDRASRSLQGVLFKVY
                     QISVLILLKKILFSFFSVCLPLFIRHIAAMLLRKTSSKTMQTVTKYLKELSGVRSDNSP
                     NSYK"
     CDS             11129..11461
                     /locus_tag="ctg62_11"
                     /transl_table=11
                     /translation="MKQLIACCGLDCENCAARIATVNNDDELREKTAKEWSVLNNTPEI
                     TAETIHCMGCRADGVKFTYCSDYCAIRKCVYEKGFNTCGDCKELDTCQVVGAVLQHAPG
                     ARENLY"
     CDS             11696..12472
                     /NRPS_PKS="Domain: oMT (51-145). E-value: 2e-11. Score:
                     34.4. Matches aSDomain: nrpspksdomains_ctg62_12_oMT.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 81.3; E-value:
                     1.3e-24)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg62_12"
                     /transl_table=11
                     /translation="MSNENKTIHDFEFNLICDFFSNMERQGPGSPEVTLKALSFVDGLT
                     DESLIADIGCGTGGQTMVLAGHVPGQITGIDLFPGFIDIFNRNARQLGLQDRVKGIVGS
                     MDALPFGEEELDMIWCEGAIYNIGFERGLKEWRKYLKPGGYIAVSESSWFTDERPAEIN
                     DFWMDAYSEMDTLPNQVTKLYKAGYLPVATFILPENCWTEHYFASKVAAQEIFRKKYAG
                     NKIAEEFSLLQMIEDELYGKYKEFYGYVFFIAKKVG"
     aSDomain        11849..12130
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg62_12_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="2.00E-11"
                     /label="ctg62_12_oMT.1"
                     /locus_tag="ctg62_12"
                     /protein_end="145"
                     /protein_start="51"
                     /score="34.4"
                     /tool="antismash"
                     /translation="DIGCGTGGQTMVLAGHVPGQITGIDLFPGFIDIFNRNARQLGLQD
                     RVKGIVGSMDALPFGEEELDMIWCEGAIYNIGFERGLKEWRKYLKPGGY"
     CDS             complement(12547..13395)
                     /locus_tag="ctg62_13"
                     /transl_table=11
                     /translation="MNISEFNINDEFIACNHITTNELNPLVEKPYHTKASIFALCTKGV
                     LKTIINHTQFRVEANALLVIPPETFVQLLHTSDDAEIYVVIFSQQLIQSSGAGKVMMDK
                     FHIIGKHYIFPLSRTDFQLYAEFMTYLSHLYQRTESPSSLVSLQTLLTYLLQGISELCP
                     ERPRIKETPGSRHFNQYRIFIRLVHTDYVREHQVSYYALKMNMRPAALCRLVKKESGYT
                     AMEIINNTIIMDAKAQLCTANTPIKDIAVSLGFNNAAFFNKFFKRHTGIPPQKFRTSSK
                     Q"
ORIGIN
        1 acctttttaa ataataacta agtatgaaac caactttatt cttattggca gccggcatgg
       61 gcagccgtta tggtggcttg aaacaattgg acggactggg cccgaatggc gaaactatca
      121 tggattattc tatttacgat gccatcaatg caggctttgg caagcttgtg tttgttatcc
      181 gtaaagattt tgagcaggat ttccgcgaca agattatttc caaatacgaa ggccatattc
      241 cgtgcgaact ggtattccag tccattgatg accttcccga aggcttcact tgccccgaag
      301 gccgtaccaa accttgggga accaaccatg ctgtaatgat gggtgccgat gtaataaagg
      361 aaccgtttgc tgttatcaac tgcgacgatt tctacggtcg tgattccttc caggtaatgg
      421 gtaaatttct tgcagccctt cccgaaggct ccaaaaacgt atattccatg gtaggcttcc
      481 gcatcggcaa cacgttgagc gaaagcggta ccgtatcccg tggattgtgc ggaacggatg
      541 cgaacaacct gctgacttcc gtagtggaac gcaccaagat tcagcgcatg gacggtgagg
      601 tgaaatacat cgatgataac ggtgaatgga ctgccactcc cgagacgact ccggtcagca
      661 tgaacttctg gggtttcact cccgattact ttgcttacag tgcagagttt ttcaagagtt
      721 tcttgagcga cccgaagaac atggagaacc tgaagagcga attcttcatc ccgctgatgg
      781 tggataagct gattaacgat ggcactgcta cctgcgaagt gctcgacaca accagcaagt
      841 ggttcggtgt gacttatccc gaagaccgtc agagtgtagt cgacaagatt caggctttgg
      901 tggatgcagg cgagtatcct gcaaagctgt tctgagtttg ttaaccaaag gcagataccc
      961 gttggggctc attctctgat tataatcgga caatagattc gcatgcctcc gctactgccg
     1021 gatggtgggt gacgaagata catgttttgc ctgcgcagtc tctgcgcagg ttttttatta
     1081 acagccgttc cgtgtcgggg tcgagggcag aagtggcttc atctaaaaga agaatgtttc
     1141 cggggcgtag cagagcgcgg gcaatggcga tgcgttgggc ttgtccttca ctgagtccgc
     1201 cacctcgttc gctgagtggg gagtctacgc cgtcgggaag gtggaagacg aagtcggcgg
     1261 tggcggtttg cagggcttga tatatggctt cttcagaagc ttgtgggttt cccatcagca
     1321 ggttgtcacg gatagttccg ctgaaaaggg tattgccttg cgggacatat acgaagttct
     1381 tgcgggtttg cggagagacg gtatgactgg tttcaagtgg atgtttggcg ggtatcaaga
     1441 gtatctgtcc ctcttgtggc gttgccagtg ccaacaatag ccggatgagc gttgtctttc
     1501 cttttcctgt ttctccgact acagctatgc agctaccggc ggggaaacgg caggagaagc
     1561 ggctgaatac cggacggtca tcgggagtgt agccaaaagt cacgtctttc agttccagtt
     1621 ccggggtaga ggcgaggaat atgctgtcac cgtccgcttc tgccggcagt ctttccaatt
     1681 ccaatagccg gtctatggcg gtaagggcat tgactacgga aggtatcagg cgtgagaggt
     1741 cgagcacggg acgctggact tttcctacca attgcaaaaa ggcggtcatc gttccgaagg
     1801 tgatacagcc tgcgctgagg tgaacggctc cccaaagaaa agccgtgagg tatccgccgg
     1861 aaaaggcaag ggccactaac atgtgggcgg aaagcgagaa acgggtacgt cccatgactt
     1921 ggctgtggag catgtcttgc aagtcatcga gtttgtccag atgccgttcg ccttgttcca
     1981 atgttttaat cactatgcga tgttgcaggc tctcttgtat gacggactgg atgcgaccgt
     2041 cactgttccg aatatcatgt gtatagcgtt tcattcgtcg catatagaaa cggctgccta
     2101 atagaaagac gggcaggatg gcaacaatca gccatggcag tgaagggtct aaaaagtaga
     2161 agaatagaaa ggctgccagc agttgtatac tcgtgacgat gaatgccggg acagaagagg
     2221 tgagcaatgt gacgatggcg gcggtgtctt gttctacccg gttcactacg tctccggtat
     2281 ggaaacgctc caattcgttc cagcggcttt gcagtaagcg cgagaagagg cggtggcgaa
     2341 gggcgttgcc cgtctctatc tgcatacggg tacttatcca agtgtcagca gctccgcaca
     2401 gtaattgggc agtcagcagg acaacggtga gaacggcgac atgcgtcagg ttgtcgtctg
     2461 ttattccggt agcggtgtct atcacccgtt tggttgcata gataaaggct agggcaaagg
     2521 ccacgcccag aatgccggtg aggcaactta gcaggatacg tccgcgttgt tcggcagata
     2581 cctctcgaat atacctaagt ttttcacgtc tgtccttttt cacttttttg tccttctgtt
     2641 gctttttcat tccttttatt ttccgggttc ttttatttct ttgtccttgc tttcttgtct
     2701 tttactcctt ttaatcggtt tatttgtata gctatcgttc cccctatcag agtcacggga
     2761 taccagagtg cttcgtacgg tgcaaattga cgcagttcgt tgcagcgtcg ggtggcgcgg
     2821 cagaaggtgt accactttcc tgcccaatat cctttggggc gtggcttgat gcggttatca
     2881 tgttgcccga agttaccggt agacaggatg tcttccaata attgttctcc tatctgcttg
     2941 gtgccttcca aggggaaagg aagccggttg gcgggcaatc ccagtcgggt gacggcaatg
     3001 tagccgaatg cttgtgcggc atgcaatagt ccgaggtcct gcaactggcg aagcagggtg
     3061 gtggcatcta tttctttgtg gcgattggca agcagacaag tccagtcgca tagctggcgc
     3121 aggccgattc cgctgttcag gaaatgtaca aaggcatgta ggaagatata aagtgcattg
     3181 aaggtggccg gaggtatggc gatactgacg gccttcgagt cctctttccc ggtttcggag
     3241 aatagggcat agtctgtttc ctgcggatac cattttctga taatctgctg aaagtgccgg
     3301 ttggcaagcg gactgttcag ccggaggatg atgcggtggt tctcgatgtg tactcctttc
     3361 aaactgtagc tggcatgctt gtcggacgct tctccctcga ctatggcgcc ttgttgcagc
     3421 aggaggcggt tggctatggg ttgtccttgt tttcctaaat agatgtcgat gtctccgcat
     3481 tgccggtgca agggagtgcg gtagttggtg ccgatgcctt gccctttcag cagtacggga
     3541 tgcagcccgg cttcccggta aagggtattg agttcgggca gaagctggtt gaggcgtttg
     3601 ttggcttgtt ctatctgtgc agtccgggca gcccatttca gatagagggc gcgtggaggg
     3661 cgcagttcgg ccggtagact gcttatgccg tcaaaagtca gtgcaagcag ggcttgtgag
     3721 tttgccatgc ggtacacggt ttcccagtcg tccggcgaga ccgaccggaa gagttgtcgg
     3781 tctgccggag tgccccacag gccggagcgt accaatgaaa agaaagcgtg ttgcatatcc
     3841 gtccttattc tatgattcct tcgcggtcaa gggagtcgat aaacttctgc gcatcgcgac
     3901 gggccgattc gttatctaca tcatagcggc tggtcagggc ttctgtcacg ctgtctgtat
     3961 cgaactcttt gttttctatc tcttgccaaa gcatggcgga agtttggttc aggctgatga
     4021 ctttgctgaa gtccacgttc gacgagccgt cttgcatgat gatgtagtca tcgcctatcc
     4081 ggtgcaggat aaatccttgt ttgattttca tggttatttt gttttatatt cttctgaaca
     4141 gggcgagcag ccagcggcga gcagggttta gcttcatcca ccagtaggag tagagcttcc
     4201 agactttgcc gtcggcggtg taccgtttgt cttttcgcat ggcttcggtc atgacgccca
     4261 ttacccgtcc gatgtcggtt tcttcggtct gggcgaggtt gccatcgcct tgcaggatga
     4321 gtatatttcc gttccgacgg atgatgcggt gaaagacgat gcgttccgtc aggtcgcgtg
     4381 ccagtacggc gacgcccggt tgcagctgtt ctgtggtgaa atcgcccagt gtcacccggt
     4441 cacggcggtc cactaagaaa ggattcatgc tgttgccccg cacggtgatg gttactgtat
     4501 gcccctcttt gatgagacgc gccacttcgg gaagcaatat ctcgttggga atgcttttct
     4561 tcatcggctg ttcagttcat cattcataac ttatccttct accgtctttc tgcaaagctc
     4621 cgtcgcttca cggtcgggca ggcatttcag atgatagacg ggtgccagcg tggcaagttc
     4681 cgtcacagtg gtgacaatgg cgttatagat ttccttgttc tgcttcaggc aagagcagga
     4741 ggggaggagg gtggcgaaag catgtgctgc tctctcttgc tctatttcat tctgcggtgc
     4801 ttgttccaag cggacgaagg cgcctacggt catggattct ttccgatagc atggtgtctt
     4861 tccgctccac ggagaaccga aaacagtggc ttgcttgccg aggctgtcca catgtactat
     4921 cggattgtca tcgttcagta gatggcagtc cgagaactgt tgcagccaga gcccggtgtg
     4981 cgtacttttg cccgtgccgc ttttccctaa gaagaggtag cctttgcctg tttcagtagc
     5041 gacaaccgag gcatgcatca gcagtgtatg gtggcgggcg gcattgaagg catagagcat
     5101 catcaagaag ttgttcagta cgaagttcgt ttcgttttcc ggagccggtg tttctgtcct
     5161 gcaggccggt aggtggatga agcattgcct gaagttatcg ttgcactcca tccaatagtt
     5221 tttcccgctt ttccgtgggg tgatggatac aaggtgtgag ctgtggggca aagggcgaat
     5281 gatgcaatcg gcatcttccc agttgaaaca tatatcatcg ggagttttcg ctatggttcg
     5341 ttttgtcgct gtttcgtcat cgtctatctc tgtttcaaag attacttttt gcgtcgtgtc
     5401 tattgtcgtg atgaacggaa tcagtgaagg caacgccttg aatatattga agtcggaagg
     5461 tttcaccatg cggaaggtgt gcggtcctac ttgataatcc aatatctgta ttctcatatg
     5521 ttttgattgt tagttgttat tcatgatact ttgggctact cagaaaaata atgaatgttt
     5581 gtgtgaatga ggaagatttg agagattttt caactgtctt gttgtcattt tttagacgcg
     5641 gaggacgcag atttataaaa gaaaatccgc tgtccgccgc atctaaaaga tagtaataag
     5701 gcgattccga tacctcttcg tttggtctgc gaggatatat tgcttccttt cttagaattt
     5761 ggcttatcgg ttctcctgac ttgttgggcc aacaatatat tctttcctcc catcgttgac
     5821 tttgtgggct gctgtatata cactgccgtc acgggtaacc tcgtaacctg ttaccaaata
     5881 ggattcattg tcgtccatat tcggatttgc cgggttgaaa ttgatgaacg ttccaccgga
     5941 cacctggatg ctggcagtgt tcttgtctgt attctttaag ttcagtaccc agtatctgcc
     6001 atccgtgtcg ttgttgggtg taccatattt gccggattca aatgttcctc catagatatt
     6061 gattttccca ttctctcttg cataaatcag gtctatctgg gtgttcagtt tctgggtgtt
     6121 atagtaagaa ccgccatgaa tatttactgt cccgtgtcct cgggcttcaa ttaccatgcg
     6181 ataaccatcg tctttcgctg tagcagatgc atcgcacttc acattgccgt tgcctgaaat
     6241 gtttagtgtt ccgttctgta cagtaaagat ttgtgtgaaa ggagtggcat cagctgtttc
     6301 tgaggaattg atgatgtcgt ggccattcag gtttaagttt gccgttgcgt ttgcagcatt
     6361 caatatgtag cctgtggcaa gctccgtctt ggcgatgttg atatttgaga gaagttttat
     6421 atccacagtt gcgttggttg ccatgtactt cagtacgctt gggtcggaga atgtacctcc
     6481 ggaaacagag atgatacttt tggcattttc ggttcccacg gatgcatcta cctttaagtc
     6541 accgttgaaa gtaccgcctg tgatattcag cttcataggt tcggtatttc ctgcactctt
     6601 ggaaatttcc acttttccat tgatgacgct cgtaccgctt accgtaaccg tgactccagc
     6661 agtgtacttt gcatagccgc atacgtcgaa tgcaaattga ttcgcattgc ttcctgcgtt
     6721 gatagtggta ttgttgatgc ttatattgcc acaattgttg cttactacgt attgggcatt
     6781 tgtgtcttct actgtcatat tatctaatgt caggttgcag tagttctgaa tcatgatttt
     6841 gttgttgtca ctcttcagcg ttccgttctt gaaagtaacg tttgaacctt cgagtaattg
     6901 acagctgttc gtttcggtgc cggtggaacc tacggtcggg tcagcaagtg taaggatctt
     6961 gccgcctaag tccatcgtca aggtttgtcc gcttgtggtc ttgaatcccg ggcaggtctt
     7021 gtcggcggtc aactttatgt tcacatttgc atttgtcttc atgtacttca gcgcgcttgg
     7081 gtcggagaat gtaccgccgg taacgttgat gaccggtgta taagtggtgc cttctgtgat
     7141 gagtgacttt gcttcggcaa tcagtgtacc gcctttgatg tttactgtgg caatgccata
     7201 tgctccactt acgttgatgg cggcgcagtc cagtcctccg gtaccgtcgc cccagttgcc
     7261 ggtgctgcct gtgcctttac tggtaatcaa ggctgtgcct tccacgttca gagtgcctcg
     7321 ttggatgcat acacctcctg cggcaccata aaccttgccg ccactgatgg tcgttgtgcc
     7381 ggattggggc agatagactg catagtcagc agtagaaatg agttctccgt ctgtgatgtt
     7441 gatgatggag ttctgcgtct tgtaattgcc gttgcctgcc actgcaaacc atccggcttc
     7501 tatcttgccg cctgtcatgg tgaagtctcc accgtccgtc actccgacgc catattggcc
     7561 gttactgttc ggagtctttc tgactgcact gatgttgccg ctttccatgg tcatggaggc
     7621 atcttcaccg gctatttcaa tcagactgcc attataagaa gccgctgtat aatcctggct
     7681 ggcaactatc ttgcctttct tctcggtaga gctgtccttc agtgtcatct tgcccaagac
     7741 gatgattttg cctgttgcgc tgttgtcggc agtcagtgta tatccgttca agtcaagaac
     7801 cacggacttt ccggcgggta cactgacgct ttgccctgtg atgtcggcat cggcggacaa
     7861 tttaaaatct tcgccgttgg cgaaagcggt ctttaggact gccacgtcgg attgaactac
     7921 aaatttgctg tcgattgttg ccggaagtga tgcttcagtt ccttttatta tatagattgt
     7981 ggtattgccg gcatcgtgta ccaattgttc tacctttcca tatatcttca agttaccgcc
     8041 ttttacggtc agcttcttta cggtgacgcc tgcattgata atcaatgtct gctgggcggt
     8101 agtggcagtc acttcattgt aagtggcttt attgcctact gctgccaatg taacggtggt
     8161 gcttggcatg gtgatggcta cagaaggagc ttcttgctct gctgtggttt ccggcacagc
     8221 caaggataca ctgttggtgg cagtggcggc gggagtactt acgctggtat tggtcttgtc
     8281 ggtcagcttt aacggggcag aagtgctggt tgtcggggct gtattgaacg ccaggttgat
     8341 gtccgagttc tgtaaaaccg ggatggcgat gccgtcgttg ctgccagaag tggtattgaa
     8401 gctgccgctg actgcaatgt cggttacggt tgctgctgtc ggtgcttctt gtgggagatt
     8461 ttttgaatca gctaaagctg tactaagcgc actgggggtt gtagcctcta ccacaacgca
     8521 atccaaagga ggtactacca atatgtctct tctgcctagg attttgtcat taagcgtctt
     8581 ggtaaaatat accttgtcgc ttccattcgt cagttgggca gtgatggaac tataagtacc
     8641 tgtgggcaaa ggaatgtaga agttgcgaga ctttatatca gctgaggctg tgaaggaggc
     8701 ggtgatttcc ttgctttcat cgctcgttac tgccagtatc gggtctgctg cggttaagtc
     8761 taccgtacaa gtacctgcaa tgttattgga ggcaataatc ttgaaagtag tggcctctgc
     8821 cggaatcttg ttgacggtca gttttatcat ggctgccatg tgcttgaagg acagagcgct
     8881 cagattgtcg ggatttgtca ccttggcata catcgggcca ttgctgctgc cgttataatt
     8941 tgtaagcgtg gcaggtagag tcatggtcaa tgtattgccg cttacgctca tgttttgttg
     9001 gtaaggatag atggagaata cagccgtttc tccgcttggc ttgctgccgt tgaaagtggc
     9061 ggaagtttga ccagcaccgc ttgcatattc taattttgta ttgctataat tactttctgc
     9121 attactacag aacaacccta gggcatcggt atcttgccat agaatcttgt attcatcgtt
     9181 tacggtagta cgggtgtcgg tacctgcgcc ttcaaacgtt gcgttaacgg tgatgtttcc
     9241 tttccacccg ctgttttcaa attcctcttg gctgcaactg aatgcggtca aggcagcagt
     9301 tgccatgcag gcaacttgca taaggtttct taatttcatc ataatgaagt cccccttagt
     9361 tttctacggt taagatgtca ttgattaggt cttccaagtc gctgctggat gccgaattgt
     9421 agctatgggt agaggtgctg cccgaatagg agcgcgtaat gggatggtaa ggttcgccgc
     9481 ttgttgcaat gactccttca ttctccattt tgataacttc gatagacgga gtgatgtatg
     9541 cttctctacc gtctggtgtg ttctgtttca tatacacaaa ttatttaaag gttaaacaat
     9601 aaaaaaaacg tgagtaacta tgtttgtata tcctttattc aggccttcgc attgcccttt
     9661 ccctggatat acaacagtca ctcacgtcgt ttgtgtatat actatccccc ctgatgggag
     9721 aaaaccatat aaacatagac gtgagcatcc ttgttgttat cttcagggaa attttcaaag
     9781 ttgcgaagtt tgaataaaga agataatttc aataatgctc ttactaatat gtaaataaac
     9841 ccactacgct atagcggatt tgtgacaaag ataattgttt tttgtttaag tgtatctatg
     9901 tttctctatt ttttttggga aaggctcacg tctctttcat ttataggagt taggagagtt
     9961 atcacttcta actcccgata actccttcaa atatttagta actgtctgca ttgtctttga
    10021 ggatgttttt ctgaggagca tagcggctat gtggcgaata aagaggggaa gacagaccga
    10081 aaagaagctg aataaaatct ttttaagcaa aattaaaaca gagatttgat atactttaaa
    10141 cagaacaccc tgcaaactcc ggcttgctct gtccggcagt ttgcagggtg gctgcttggt
    10201 tttctcgcgt gtacgtagct ccttatgcca cgaacggaag tcgatgccat agcaattttt
    10261 cataataaga ctttccatat ttttgcaaat gtccgtactg cctttggctg aaacaattta
    10321 tataagtaat tgaagtttcg taagtgagta tgcctgctga taaatgggaa tttatcgcac
    10381 agagcgcgaa gcctgctctc ataacctatg gagagcacga gtgaaagctt gtggattttt
    10441 atctaaaaca taggtattcc tttactcttc tccctttgtt tgtctgctgt ggcataggga
    10501 atttatgacg cctaacggcc atgaacaacc ctgctttcga ccataaagca atcgtttgac
    10561 gaccgtaagc agagttgttc atggccgtta ggcgtcacta actccagagc tattacagat
    10621 gaagtacgta gcccgaacct attgcgcaca aggcgcaaac gtattataca acggtgtaaa
    10681 agacattaga gtgcattatt catagtcggc ctttgattcc cgataactcc tactatgctc
    10741 ctacagtcca actccatatc cgttgacttc acagtaagga caagcccgaa aatgcaggaa
    10801 aaccgaacct gccgattcat gtaatctgca tgcagtatta tgctagggga tagcagctta
    10861 ctgcaaaact caggcgtttc aggcaggtgg aagcaaattt tgcttccacc ttttcaggtt
    10921 gcttccatcg cagggcaaat gccgatggac agggggatgc aggaggtggg tggaagtgtg
    10981 gaagcaaagt gatggaaaat taatttggca ttcacacaat aataaccgta tatttgtagc
    11041 atggctgtct gcctcctctt aaattcagat aaagaggagg tagacaaatg cttgctatga
    11101 gaaacacata aatggttata accaagtgat gaaacaatta attgcatgtt gcggactgga
    11161 ttgcgaaaat tgcgccgccc gtatagccac tgtcaataat gacgatgagc tgagagagaa
    11221 aaccgccaaa gagtggagtg tgctgaacaa tacgccggaa attacggcgg aaaccatcca
    11281 ttgtatgggg tgccgtgcag acggggtgaa gtttacctat tgcagcgatt attgtgctat
    11341 ccgcaaatgt gtgtacgaaa aaggtttcaa tacttgtggc gactgtaagg aactggatac
    11401 ttgccaggtg gtaggtgcgg ttcttcagca tgcgcccggt gcaagggaaa atctttatta
    11461 accgtaaaat ctttgattaa ataaaatatt gcttatcttt gcagtatgac aaagacattt
    11521 aaatcggatt tggttttgta aacaatctgt gttccatgca cagattgtcc cctttcgttt
    11581 actttcggat aacttctttc gagagtgttt ttctattgtt ataattcaag tttaatccgc
    11641 atattatgct gaaggtgttg tgatactttc cgtatatgca aaatatagta agaaaatgag
    11701 taacgaaaat aaaactatcc acgatttcga atttaattta atctgtgact ttttctccaa
    11761 tatggaacgg caaggccctg gcagtcctga agtgacgttg aaggcattga gctttgtaga
    11821 cggtcttacc gatgaatccc ttattgccga tatcggttgt ggaacgggtg gtcagacaat
    11881 ggtattggct ggccatgttc cgggacagat taccggaatt gaccttttcc ccggctttat
    11941 tgacatcttc aaccgtaatg caaggcagtt gggcttgcag gacagagtaa aaggaattgt
    12001 cggttcaatg gatgccctcc ctttcggtga ggaggagctg gatatgattt ggtgtgaagg
    12061 tgctatctat aacatcggct ttgaacgtgg cttgaaggag tggcgtaaat atctgaaacc
    12121 gggagggtat attgccgtat ccgagagttc atggtttacg gacgaacgtc ctgcggaaat
    12181 caatgacttc tggatggacg cctattctga aatggataca cttcccaatc aggtgaccaa
    12241 gttgtacaag gcaggttatc ttcccgttgc tacattcatt ttgccggaga attgctggac
    12301 agagcattac tttgcttcaa aggttgcggc tcaggagatt ttccgtaaga aatatgccgg
    12361 taataaaatt gccgaagagt tcagcttact ccaaatgatt gaggatgaac tgtacggcaa
    12421 gtataaggaa ttttacggtt atgtgttctt tattgccaag aaggtaggct gatgacggac
    12481 ttctcttatt gaggaatgcg ggtattctca ggacagaata tccgcatttt gggttttgag
    12541 tagattttat tgttttgagg atgtacggaa cttctgagga ggtattcccg tatgacgttt
    12601 aaagaatttg ttgaagaagg ccgcattatt aaaacctaga ctcacggcta tatcctttat
    12661 cggagtgttg gcggtacaaa gttgtgcttt ggcatccatg atgatagtat tgttgatgat
    12721 ttccatggct gtatatcctg attccttttt gacaaggcgg caaagagctg ccggtctcat
    12781 attcattttc aatgcataat aggacacttg atgctcccgg acatagtctg tgtgtaccaa
    12841 tcggataaaa atgcggtatt ggttgaaatg cctgctgccc ggagtctctt ttattctagg
    12901 gcgttccgga cagagttcgg atataccttg taacagatag gtcagtagag tttgcaatga
    12961 aactagactt gaggggcttt ctgttctttg gtagaggtgt gacaaatagg tcatgaactc
    13021 ggcataaagc tggaagtccg ttctcgatag aggaaaaata tagtgtttgc ctataatgtg
    13081 aaacttatcc atcatgacct tgccggcccc tgaactctgg ataagttgtt gggaaaatat
    13141 gacgacatat atttcagcat cgtctgacgt gtgtagcaat tgtacgaagg tctcgggagg
    13201 aataactagg agggcgttag cttcaaccct gaattgagta tggtttatga tagttttcag
    13261 aactcctttg gtgcatagag cgaagatact ggccttggtg tggtatggct tttccactag
    13321 cggattcagt tcattggttg tgatatgatt gcaggcaatg aactcgtcat ttatattgaa
    13381 ttcggatata ttcatgttgg agattttaag acgcaaaaat gggggataat aatgtataaa
    13441 tgacagaggt aacagttaaa atcaatatta cgctcaactt atctctgtta aataaggtaa
    13501 agttgtgaat aatagaatat aagtaactaa tcaaaattaa gcagcataat ggctaaagtt
    13561 aatattcagt cg
//
