LOCUS       c00068_gnlPro..        14780 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PEOGHBDE_68.
ACCESSION   c00068_gnlPro..
VERSION     c00068_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 07:19:18
            Original ID  :: gnl|Prokka|PEOGHBDE_68
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3680
            Orig. end    :: 18460
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14780
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[13680:18459]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14779
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..14780
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14780
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             1659..3500
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_U32"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg68_6"
                     /sec_met_domain="Peptidase_U32 (E-value: 9.9e-76, bitscore:
                     244.3, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIKPRRIELLSPAKDLNCGIEAINHGADAVYIGAPKFGARAAAG
                     NTLEDIRALCEYAHLYNARIYVALNTILREEELPEAEQLIRQLYLAGADALIVQDMGIT
                     RLNLPPIPLHASTQMDNRTPEKVKFLEAAGFTQVVLARELSLNEIRCISEQVSVPLEVF
                     VHGALCVSYSGQCYLSAALSGRSANRGECAQYCRLPYSMVDANGTEIVHNKHLLSLKDM
                     NRSDQLEALLDAGASSFKIEGRLKDVTYVKNITAYYRKKLDAILARRPEYCRASAGKST
                     YEFEPVAEKSFNRGFTPFFLHERTKDIAAFNTPKSLGEPVGTVKELKGNSFTIAGVKQL
                     NNGDGLVFFNSRGELEGFRVNRVEANRVFPLDMPDIKPKTPLYRNFDQVFEKQLAKPSA
                     ERKLAVKIEFLDNPFGFTLVMEDETGARVMLTEPFDKELARRDQADNIRTQLAKLGNTP
                     FEASEVHIGMGENWFVPSSLLADMRRKAVEKLQSDRMIRYQRELSRKVEPAKEVPFPER
                     QLTYLGNVSNSRAEAFYKAHGVETVADAFELKPEKDVPLMFSKHCLRYSMGWCPTYQKE
                     KSPYKEPYYLLYKDTRLRLQFDCKRCQMLVYEAPSQK"
     CDS             3547..4365
                     /locus_tag="ctg68_7"
                     /transl_table=11
                     /translation="MKQQLFAFLLVLFTLISCGDKPLDPSKPVYVTVKTTMGDVTVLLY
                     DDTPLHRDNFIRLCQSGEYEGMLFHRIIKDFVVQGGDPTSKAHEPGVLYGDGDGGYTVP
                     AEILPNHFNKRGALIDAKESDDVNPERASAGTQFCFVQGKKHSDAELDEKEVRINQIRR
                     NWLYYKFLDRLKKEDPALAADSLETELTNRALVMVEDTLADLGPYVIPAEHREVYKTVG
                     GVPHLDSSVTIFGEVVDGFDIVEKMSLVKTDKNDRPIRDVMIKSTKVFQK"
     CDS             4520..4861
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Epimerase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg68_8"
                     /sec_met_domain="F420_oxidored (E-value: 1.6e-07, bitscore:
                     22.3, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Epimerase (E-value: 1.4e-10, bitscore:
                     31.4, seeds: 96, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIVIIGATGYVGSAILKEALGRGHQVKAIVRDPSKLTLIHPHL
                     KVVGGSVTDTDFLSRELAKSDAVISAFNPGWXXXXLHDCGRIPIFMKRHWKAMALSFVP
                     FATPVCIVS"
     CDS             4861..5196
                     /locus_tag="ctg68_9"
                     /transl_table=11
                     /translation="MVGGAGSLLVAPGRQLMDEPDVPKKLLPGIRGMAKVYTDLLLPEK
                     SVDWVFLSPAANMAPGERTGKFRLGKDELIVDESGDSNISVEDFAVAMIDELEQEKHHQ
                     ERFTLGY"
     CDS             5307..5933
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg68_10"
                     /sec_met_domain="HAD_2 (E-value: 3.3e-09, bitscore: 27.5,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKIKNIVFDLGGVFIDLDHDQAVRRFKEIGVEDAEQLLDPYEQK
                     GIFLEVENGTISADEFCQKLQEHTGKDLTYEDIKSGWLGFIADTPQYKLDYVLKLREHY
                     SVYLLSNTNPIIQEGWARTNEFTPAGRPIGAYFDKMYTSYEVGVTKPDRRIFDYMIKDS
                     GLIPAETLFVDDGKSNIEVGRTLGFITYQPQNREDWREAIDALLK"
     CDS             complement(5949..7640)
                     /locus_tag="ctg68_11"
                     /transl_table=11
                     /translation="MIENGEKREKKMRFSYFDREQNIWLMTRTDITEIKEERKQKLLLQ
                     EALQSATAANRAKSDFLSRMSHDVRTPINAIVGMTAIAGLHMNDQNRIADCLKKITISS
                     KLLLNLINEVLDMSKLESGKIMLTEETFKLDELLESLFIMVQSAFEAKKQKLVIHSKVK
                     HECLIGDVQRIQQALLNMLTNAIKYTPNKGLIQISVEEKPSVYNGYGQFEIAVTDNGIG
                     MKPEFLSKVFEPFERSDDKAIRNIQGTGLGMAISRHIAQMMNGDILVESEYGKGSKFTM
                     RFHVKLGGMDEYDNNLLIDLPVLVVDDDDISCEIACENLQELGMKPEWVLSGQDAVQKV
                     SDGNKYFAIIIDLMMPNMNGIETTYKIRECVGPDVPIIIISAYDYSDYEIEALKAGVNG
                     FICKPIMKSKLFLLMKKFATNKKEEEEVTIVPSIVASFPGKRILVVEDNDLNREIAYEL
                     LQETGAEIETASDGLEAVNKVSASPEGYYDFIIMDIQMPVMDGLEATRQIRLLDRQDTK
                     DLPIVAMSANAFAEDVRLSLEAGMNEHIAKPIEIDRLYSVMGKWFR"
     CDS             complement(7637..8266)
                     /locus_tag="ctg68_12"
                     /transl_table=11
                     /translation="MDKRLTSNKSLANYQYLMDTIWTIYLEDGSVEIQKDSMIPELENT
                     KHDYVILNNTIKNDVYPPDHILWDETVSLEAFHKMIAEGCFHKKFDMRFCNKHFGFEWH
                     EAFIDILTNKEGIPDRVVLSSHNVNDFRKSQIIETAVKAEYDYVIYIEASKNSYVMYTS
                     STESETPPPVASSNYEAVVAEYNRQYMEPEFCDAMTEKMSIFYMVP"
     CDS             complement(8280..8642)
                     /locus_tag="ctg68_13"
                     /transl_table=11
                     /translation="MTSEYKEKLQAYGVNLDSALNRFMDNEQFYERILSKFPMDENFIL
                     MERSLNENNISQAFRHAHTLKGLAATLDLTNISDILIPMTEKLRAGESEGIQDLFDQLK
                     VQYKLICDLITEHKAR"
     CDS             complement(8943..9983)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg68_14"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 9.1e-50, bitscore:
                     160.2, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKILVAGGTGYIGSHTTVELQNAGYDVVIIDDLSNSNIEVLDG
                     IEKITGIRPEFIKLDLKDKEGTREALKAHPGINGIILFAASKAVGESVQQPLKYYRNNV
                     VTLVNLLELMPEFNIEGIVFSSSCTVYGQPDPENLPVTEDAPIKPATSPYGNTKQINEE
                     IIRDTIHANAPFKSIILRYFNPIGAHPSAEIGELPNGVPQNLIPYLTQTAIGIRKELSV
                     FGDDYDTPDGSCIRDYINVVDLAKAHVIAMDRMLGGKTEENVEYFNLGTGNGVTVLELI
                     NTFEKATGVKVPHKIVGRREGDIEKVWANPERANKVLGWTAKETLSDTLASAWKWQEKL
                     RERGIQ"
     CDS             complement(10001..10585)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg68_15"
                     /sec_met_domain="Rnf-Nqr (E-value: 7.3e-59, bitscore:
                     189.1, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFIAAVFVNNVVLAQFLGICPFLGVSKKVETAAGMGAAVT
                     FVLTIATIVTFLVQKYILDKFGLGFMQTISFILIIAALVQMVEIILKKVSPALYQALGV
                     FLPLITTNCCILGVAILVIQKEYNLLESVVYAISTAIGFALALVIFAGIREXXXXGFDT
                     CSRRYERYPYCADNSRFTGNGVYGILRNRII"
     CDS             complement(10604..11188)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg68_16"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.4e-70, bitscore:
                     227.2, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNMKVLMNGIIKENPTFVLLLGMCPTLGTTSSALNGMSMGLATM
                     FVLICSNMVISALKNLIPDMVRIPAFIVVIATFVTVVQMCMEAFVPALYASLGLFIPLI
                     VVNCIVLGRAEAFAAKNGVIPSAFDGLGMGLGFTLALTLLGATRELLGTGKLFGLTLMP
                     EQYGSLIFVLAPGAFIALGYLIAIVNKLRKA"
     CDS             complement(11181..11786)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg68_17"
                     /sec_met_domain="FMN_bind (E-value: 4.9e-25, bitscore:
                     78.5, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLSLTIICLVAGAILAGVNMYTTGPIAASKAAALEAAIKAVTPE
                     FDNKPSEDAYMAVTGDGDSLKIYPATKGGEFVGAAVESNTKKGFSGEIKVIVGFDKEGK
                     LLNYSVLQHAETPGLGAKMQEWFSTDKNKQSVLGRSLSTGPLKVTKDGGNVDAITAATI
                     TSRAFLDAVNRAYSAFAGTDGVTGATTANTNEGGNDNE"
     CDS             complement(11819..12778)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg68_18"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 7.3e-120,
                     bitscore: 390.1, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENNLIVSPSPHIHGGDSISKNMYGVLIALVPAFLVSLYYFGLGA
                     LIVTATSVVACVLFEYLIQKFLMKKEPTVCDGSAILTGVLLAFNLPSNLPVWIILIGAL
                     AAIGIGKMSFGGLGNNIFNPALVGRVFLLISFPAQMTMWPEVGQLTAYTDATTGATVLS
                     LMNEGALDKLPTLVDMLLGKMGGSLGEVSALALLLGLVFMLWKKIITWQIPVSILLTVF
                     VFTGIMHLVNPVQYASPFVHLLSGGLMLGAIFMATDYVTSPMSKNGMLVYGVGIGILTT
                     VIRLFGSYPEGMSFAILIMNAFTPLINSYIKPKHFGGK"
     CDS             complement(12791..14122)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg68_19"
                     /sec_met_domain="Fer4_10 (E-value: 3.2e-10, bitscore: 30.5,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 2.7e-17, bitscore: 52.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 9e-51, bitscore:
                     162.2, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 3.3e-32, bitscore: 101.0,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.9e-05, bitscore: 15.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRTFRIGGIHPPENKLSAGKKITGLAIPKQVIIPLSQHIGAPAQ
                     AVVKKGDTVKVGTLLAKAGGFVSANIHSSVSGKVNKIDNALDASGYKRPAIYIDVEGDE
                     WEESIDRSETLVKECPLPSKEIVDKIAAAGIVGLGGATFPTQVKLMPPPGSKAEIIIIN
                     AVECEPYLTSDHSLMMEKAEQILVGVTLLMKAVNVTKAVIGIENNKPDAIAHLSKLATA
                     YKGIEIMPLKVQYPQGGEKQLIDAVIRRQVKSGALPISAGAVVQNVGTAFAVYEAVMKN
                     KPLFERVVTVTGKAVTNPSNFLVRMGTPISALIEAAGGVPENTGKIIGGGPMMGKALIA
                     PEVPVTKGSSGVLLLTKEESVRKPMRDCIRCAKCVSVCPMGLNPTLLMNATEFAEWDLA
                     EKNYITDCIECGSCSYTCPANRPLLDYIRSGKGKVMGIIRARKS"
     CDS             complement(14135..14779)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 40; E-value:
                     1.6e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg68_20"
                     /sec_met_domain="Fer4_7 (E-value: 5e-13, bitscore: 40.0,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 7.8e-12, bitscore: 35.1,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 1e-09, bitscore: 28.6,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 9.4e-07, bitscore: 19.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="CQARPRTNQYDGVKSCTIASSLYGGETNCTFGCLGYGDCESACTF
                     DAIHVNPTTGLPEVDEDKCTSCGACVKACPKNIIELRKKGPKSRRIFVSCVNKDKGAAA
                     RKACANACIGCGKCVKECPFEAITLENNVAYIDYRKCRLCRKCVAVCPTGAIHELNFPP
                     RKEAAPAVDADKVKPVTPKAASTPKAEAPTKVEAAPATAPETITKEETTQK"
ORIGIN
        1 tgatccgtcc gcgccgtttc gggaaatcgt tgttcctgaa tatgcttaac tgctattacg
       61 atgtgaaata tgccgaccgt tttgaggaac tgttcggcaa tcaatacatc ggcaatcatc
      121 cgactgctga acagggtaaa tacctggttt tacgttttaa tttcagcatg gtaagggcta
      181 cggacgataa actggaagct gccttcaacc ggcatatcag tctggaaaca gcgtattttg
      241 ccagcgtata tgcttcttat tttaaacctg atttccagga acagctaaaa ttgattccgg
      301 aggctgccgg acgtttggaa tatatttgcc tgtgtgccaa agaacaaggg ttgtctatct
      361 acttgctgat cgacgaatac gataatttta ccaatacgat attatcctct aaaggaaatg
      421 atgtgtatca ttctttgacg cacgattcag gtttctatcg ctcatttttt aatgtggtaa
      481 aaggtgttac caccggagcg gaagcccctg tgaaacgaat gttcattacc ggtgtatcgc
      541 ctgttacgtt ggatgatgtg acgagtggtt tcaatatcgg gacgaatata acgacagatg
      601 aacggtttaa ttcgatggtt ggtttcagcg aatcggaact gcatgagatg ttatcttatt
      661 accaatcgga aggtatgctg gtcgattcta tcgatgatat tgtccggatg atgaaaccct
      721 ggtacgataa ttactgtttt gccaaagaat gtatcgggca aacgatgtat aattcggata
      781 tggtgctcta tttcctgaat aattatttac agaagaaacg tccgccttcc gaaatggtcg
      841 accgtaatat ccggacggat tacagcaaat tgcgccattt tatccgtatc gacaggatgc
      901 aggaagaagg ttgttcggtc attacaaagt tgatcgatac cggcgaagtg aacggaaacg
      961 tgataaaaga cagttttcca gcagagaacc tggccgatcc gggtaacttt acctcactgt
     1021 tatattattt cggtttgttg acttatgacc ggatggaata tggcgaaacg atcatgaaag
     1081 tacccaacct ggccgtccgc gaacagattt acagttatct ggtggaagcg atgaaagaac
     1141 gtgagtcggt cgtttttcct tttatggact tgtccgaccg gatgcggcgt atggcttatt
     1201 tcggggagtg ggaagctgct ttggactttt ttgcccgtca ggttgataag aaagcggttc
     1261 ttcgtgatgt gatctatcag gagtcgacca ttaaaacact gatggttgct tatatggggt
     1321 tgacggatta ctttattatc tggcctgagt ttgaagcggg ccgtggtttc tccgatcttt
     1381 acctgatgcc caacctggca aactatccgg atatgcaata ttcctatctg gtagagttga
     1441 aattcctgaa acgggatgat acgacaaccg atgtggaagc cttattgcag gaagccgaaa
     1501 aacaattgca ccgttacgct actgacgaga agatactcag tagcaccggt aacactcgct
     1561 tacgcctgct agccgctgtt taccgtggct ggcaaccgga ggcaatgcgc gaatttgttt
     1621 tgtgagttgt acttttttga taaatcagaa ataacaatat gtcaataaaa ccccgccgca
     1681 tagaattatt atcgccggct aaagatctga actgtggtat tgaagccatt aatcatgggg
     1741 ctgatgccgt gtatatcggt gcgccgaagt ttggggcccg tgccgctgcc ggaaatacgt
     1801 tggaggatat tcgtgctctt tgtgaatatg ctcatttata taatgcccgt atctatgtgg
     1861 ctttaaatac cattctgcgg gaagaagaat tgccggaagc ggagcaactg atccggcaac
     1921 tctatctggc aggagctgat gctctgatcg tacaggacat ggggatcact cgcttgaatc
     1981 tgccgcctat cccgctgcat gccagcacac aaatggataa ccgtacgcct gaaaaggtga
     2041 agttcctgga ggcggccggt tttacacagg tggttctggc gcgtgaattg tcgttgaatg
     2101 agattcgttg catatcggaa caggtctctg tcccgctgga ggtttttgtg catggcgcat
     2161 tatgtgtgag ttacagcggg cagtgctatc tgagcgcggc tttgagcggg cgaagcgcaa
     2221 accggggaga gtgtgcgcaa tattgccggt tgccttattc gatggtggat gcgaacggga
     2281 cggagatcgt tcataacaaa catttgttat cactcaagga tatgaaccgt tccgaccaac
     2341 tggaagccct gctggatgcg ggtgcttctt cttttaaaat agaagggcgc ttgaaagatg
     2401 tcacttatgt aaagaatata acggcttatt accggaagaa actggatgct atcctagcac
     2461 gtcgtccgga atattgccgt gcatcggcgg gtaagagtac ctatgagttt gagccggtag
     2521 ccgagaaaag tttcaaccgg ggatttactc ctttcttcct gcatgaacgt acaaaagata
     2581 tagcagcttt caatactccg aaatcgttag gtgaacctgt cggaaccgtc aaggaactga
     2641 aaggcaattc gtttaccatc gccggagtga agcaactgaa taatggggat ggcttggtat
     2701 tcttcaatag tcgcggtgag ttggaagggt ttcgtgtcaa cagggtagag gcgaatcgtg
     2761 tctttccgtt ggatatgccg gatataaagc ccaagacgcc tttgtatcgt aactttgacc
     2821 aggtttttga aaagcagttg gcgaaacctt ctgccgaacg taagctggct gtaaagatcg
     2881 aattcctgga taatcctttc ggttttacat tggtgatgga agatgaaacg ggagcacgtg
     2941 tgatgctgac cgagccgttc gataaagagc tggcacgtcg tgaccaggcc gacaatatcc
     3001 ggacgcaact tgccaaattg gggaacacgc cgtttgaagc atcggaagta catataggaa
     3061 tgggggaaaa ctggttcgtc ccgtcgtctc ttctggcgga tatgcgtcgc aaggccgtag
     3121 agaagttgca gtcagatcgt atgatccgtt atcagcgtga actctcgcgt aaggttgaac
     3181 ctgcgaaaga ggttcctttt ccggaacgcc agttgactta tctggggaat gtatcaaata
     3241 gccgggcgga agctttttat aaggcgcatg gagtagagac ggttgcagat gctttcgaat
     3301 taaagccgga gaaagatgtt ccgttgatgt ttagcaagca ttgcttgcgg tatagcatgg
     3361 gatggtgtcc aacgtatcag aaagagaagt caccttataa ggaaccctat taccttttat
     3421 ataaggatac ccggctgagg ttgcagtttg attgtaagcg gtgtcagatg ctggtgtatg
     3481 aagcacctag tcaaaagtaa caatcaattc tgataatgac tgcattaata ataaaaacga
     3541 ctcgttatga aacaacaact attcgccttt ttactcgtct tgtttacttt gatctcttgt
     3601 ggcgataaac cgctggaccc ttcgaaaccc gtttatgtga cagtgaaaac gactatggga
     3661 gatgttactg tcctgttgta tgatgacact cccttgcatc gtgataactt catccggttg
     3721 tgccagtcgg gtgaatatga ggggatgcta tttcaccgta tcattaaaga ctttgttgtg
     3781 caaggcggtg atccgaccag caaagcccat gaaccaggtg ttttgtatgg agacggtgat
     3841 ggaggttata ccgttcctgc cgagatactt cccaaccatt tcaataaacg aggtgctctg
     3901 atcgatgcca aggaaagcga tgatgtaaat cccgaacgtg catcggccgg aactcagttt
     3961 tgttttgtgc aggggaagaa acattctgat gctgaactgg atgagaaaga ggtacggatc
     4021 aaccagattc gccgtaactg gttatattat aaatttctgg accggttgaa gaaagaagac
     4081 ccggcactgg ctgccgactc tttggaaacg gaactgacaa accgtgcttt ggttatggtg
     4141 gaggatacat tggctgacct gggcccgtat gttattcccg ccgaacaccg cgaagtatat
     4201 aagacggttg gcggagtgcc ccacctggat agttccgtga cgatcttcgg agaagtggtg
     4261 gacggtttcg atatcgtaga gaaaatgtcg ctggtgaaaa cagataagaa tgatcggcct
     4321 atccgggatg ttatgatcaa atcgacgaaa gtatttcaaa agtaactagt ccccatactt
     4381 ggcacggggc cgcataaggg ctgtctgtat caattgataa taggatatat gggcggtgcc
     4441 tttgcgatcc cgtgtcaggc acgggaacag tttgccatcg tatgttgttc tatagaaagt
     4501 aatcaaacaa catacagtca tgaagaaaat agttatcata ggcgcgaccg gctatgtcgg
     4561 atccgctatt ctgaaagaag cattaggcag agggcatcaa gtaaaagcca tcgtcagaga
     4621 tccgtcgaaa ctgactttaa tccatccgca tctgaaagtc gtgggaggga gtgtgaccga
     4681 tacggacttt ttatcccgcg aactggctaa gtcggatgcg gtgatcagtg cttttaatcc
     4741 gggctggnnn nnnnnnnttc ttcatgactg tggtcgaatc ccaatattta tgaagagaca
     4801 ctggaaggct atggctctat cctttgtgcc gttcgcaact ccggtgtgca tcgtttcctg
     4861 atggttggcg gagcaggcag tttgttggtg gctcccggtc gtcagctgat ggatgaaccg
     4921 gacgttccca agaaactttt accaggaata cgagggatgg caaaggttta taccgatttg
     4981 ttgttgccgg aaaagtcggt ggattgggtt ttcctgagtc ctgcggctaa tatggcaccg
     5041 ggagagcgta ccggaaagtt ccgtctggga aaagatgaac tgattgtcga tgaaagtggg
     5101 gatagcaata tctccgtaga agatttcgct gtagccatga ttgatgaact ggaacaggaa
     5161 aagcatcatc aggagcgatt tacactcggg tactaagtgt ctttggcaaa aacagttgca
     5221 gtcattcgaa tagttgttgc tttacactta ttatgcttat ctttgtcagg aagtagagat
     5281 aaagatagat gtaaaaagag ataattatgg caaagattaa aaacattgta tttgatttag
     5341 gaggagtttt tatagacctg gaccatgatc aggcagttcg tcgtttcaaa gagatcgggg
     5401 tggaggatgc ggaacagttg ctggatcctt atgagcagaa aggtatcttt ctggaagtag
     5461 aaaacggtac gatcagtgct gacgagtttt gccaaaagct tcaggagcat acggggaagg
     5521 acctgacgta tgaagatata aaatccggtt ggctgggatt tatcgccgat acgcctcaat
     5581 ataagctcga ttatgtgttg aaacttcgcg agcactacag tgtttatctg ttgagcaata
     5641 ccaatcccat catccaggaa gggtgggcaa ggacaaacga gtttactccg gcaggtcgtc
     5701 cgatcggtgc ctattttgac aaaatgtaca cctcgtatga agtcggcgta acgaaacccg
     5761 accggcgtat ctttgactat atgatcaaag acagcggact gattccggca gagacgctct
     5821 ttgtggatga tggtaaaagc aatatcgaag taggacgtac attgggcttc atcacctacc
     5881 aaccccaaaa cagggaagat tggcgtgaag ctatcgatgc gctgttgaaa taaaccgatt
     5941 gggggtattc aacggaacca ctttcccata acactgtaaa gcctgtctat ttctatgggt
     6001 ttggcgatat gttcgttcat tccggcttcc aggcttagcc gcacgtcttc ggcaaaagcg
     6061 ttggccgaca tggctacgat cggtaagtcc ttggtgtctt gccggtcgag aagacggatt
     6121 tgccgggtgg cttcaagacc gtccatgaca ggcatttgta tatccataat tatgaaatcg
     6181 taatatcctt caggggaagc ggaaaccttg tttacggctt ccagcccgtc gctggctgtt
     6241 tcaatttcag caccggtttc ctgtagcaat tcataagcga tctcacggtt caggtcgttg
     6301 tcttccacaa cgagtatccg tttgcctggg aaagaggcga cgatagatgg tacgatagtg
     6361 acctcttctt cctctttttt gtttgtggca aactttttca tcaggaggaa cagtttggac
     6421 ttcatgatag gcttacagat gaaaccgttg accccagctt tcaaggcttc gatttcgtag
     6481 tcggaatagt cgtaagccga aatgatgatg ataggaacat ccggtcctac gcattcccgt
     6541 attttgtagg ttgtttcaat gccattcatg ttgggcatca tcaggtctat gatgattgca
     6601 aaatacttgt tcccgtcgct tactttctgt acggcatcct gaccggaaag aacccattcc
     6661 ggcttcatcc ctaattcttg caggttttca caggctattt cgcaggatat atcatcatca
     6721 tccacaacca ataccggcag gtctattaat agattgttgt cgtattcatc catgcctccc
     6781 agtttgacat ggaatctcat ggtgaatttg gaaccttttc catattcgct ttctaccagg
     6841 atatccccgt tcatcatctg ggcgatatga cgactgatcg ccataccgag tccggtaccc
     6901 tggatattgc ggatggcttt atcgtccgac cgttcgaacg gctcgaatac tttgcttaag
     6961 aattcaggtt tcatccctat gccattgtcc gtgacggcta tttcaaattg cccgtaaccg
     7021 ttataaacgg aaggtttctc ctcgactgaa atttgtatta gtcctttgtt cggggtatat
     7081 ttgattgcat ttgtcagcat attcaacagt gcttgttgta tgcgttgtac gtcaccgatc
     7141 aggcattcgt gctttacttt gctgtgtatt actaactttt gcttttttgc ttcaaaggcc
     7201 gactgcacca tgataaataa actttccagc agttcatcga gtttgaatgt ctcttccgtc
     7261 agcatgatct taccgctttc gagcttcgac atatccagta cttcgtttat caggttgagc
     7321 aggagcttgg aagatatggt tatcttcttc agacaatcgg ctatgcggtt ctggtcgttc
     7381 atatgaagac cggctattgc cgtcataccc acgattgcat ttatgggagt acgtacgtca
     7441 tggctcattc gtgacaggaa gtctgacttg gcacggttgg cggcagttgc gctctgtagg
     7501 gcttcctgca acaatagctt ctgttttctc tcttccttga tttcagttat atcggtcctg
     7561 gtcatcaacc agatgttttg ttccctgtcg aagtagctga atcgcatttt cttttcacgt
     7621 ttttcaccgt tttctatcat ggtaccatat aaaatatact cattttctcg gtcattgcat
     7681 cacaaaattc cggttccata tactgtcggt tgtactctgc aactaccgct tcatagttac
     7741 tgctggctac cggaggagga gtttcgcttt ccgtactgga agtgtacatg acataactgt
     7801 ttttagatgc ttcgatataa atcacatagt cgtattctgc ttttacggct gtttcaatga
     7861 tttgtgattt cctgaaatca ttaacattgt ggctggagag gacaaccctg tcgggtatgc
     7921 cttctttgtt agtcaagata tctataaagg cttcgtgcca ttcaaaaccg aaatgtttgt
     7981 tacagaaacg catgtcgaat tttttgtgga aacatccttc ggctatcatt ttatggaagg
     8041 cttcaagcga aactgtttcg tcccataaaa tatggtcagg cggatagaca tcattcttta
     8101 tcgtgttatt gagaatgacg taatcatgtt tcgtattttc caactccgga atcatggagt
     8161 ctttctgtat ttcgacactt ccgtcctcca ggtagatagt ccagatagta tccatgaggt
     8221 attggtagtt agccaatgat ttatttgatg taagcctctt atccatgcag tttgttttat
     8281 tatcttgctt tgtgttcggt aatcaggtcg cagattagtt tgtattgtac tttcaactga
     8341 tcaaacaggt cttgtatacc ttcactctct ccggctctga gtttttccgt catcgggatc
     8401 aatatgtccg atatatttgt caggtcaagc gttgccgcca gtccttttaa tgtatgggca
     8461 tgtctgaaag cctgggaaat attattctca ttgaggcttc tttccatcag gatgaagttt
     8521 tcatccatag ggaatttgga gagtattctt tcataaaact gttcattatc catgaaacgg
     8581 tttaatgcac tgtccaggtt aactccgtac gcttgtaact tctctttata ttcgcttgtc
     8641 atgtttttta tcgccattta tataacaaat catctgtctg ttacgaaagg aatccccaaa
     8701 agtagataaa aaatatatat ggagatggaa aaaacgttat aattcaatag gaatgtatgc
     8761 ttttttctgc tatttgacga atccgatcct ccgacgagcc tgttttgatg tctgatgttg
     8821 gttttgaagc tcagttgacg tttcattgat aagttccggt tgtaatgtgg gggatcaaga
     8881 aaaatgccgg aagaaatctc tggagaatct tccggcatgc ttatttaaaa aagacttttc
     8941 ttttattgga taccgcgttc gcgcagtttt tcctgccatt tccaggcaga agccaatgta
     9001 tcggacaatg tttctttagc agtccatccc aataccttat tggcacgttc cggattagcc
     9061 caaacttttt cgatatcacc ttcgcgacga cctacgattt tgtgaggaac ttttacaccg
     9121 gtagcttttt cgaatgtatt gatcagttcc aacaccgtta caccgttacc ggttcccagg
     9181 ttgaaatatt caacattttc ttcagtttta ccacccagca tacggtccat agcgattacg
     9241 tgtgcttttg ccaggtcgac tacattgata tagtcgcgga tacaagagcc gtcaggtgta
     9301 tcatagtcat caccgaatac gctcagttcc ttgcggatac cgattgcagt ctgtgtcaga
     9361 tacgggatca ggttctgggg aacaccgtta ggcaattcgc cgatttctgc actcgggtga
     9421 gcaccgatcg ggttgaagta acgcaggata atgctcttga acggagcgtt tgcgtgaata
     9481 gtatcgcgga tgatctcttc gttgatctgt ttggtgttgc cataaggaga agtagccggt
     9541 ttgatcgggg catcttctgt tacaggcagg ttttcaggat caggctgtcc gtaaacggta
     9601 caggaagaag agaatacaat accttcgata ttaaattccg gcatcagttc cagtaggttt
     9661 accagtgtaa caacattgtt acggtagtac ttcagcggct gctgaaccga ttcgccaaca
     9721 gctttgcttg ctgcgaaaag gatgataccg ttgatacccg gatgagcctt caatgcttcg
     9781 cgggttcctt ctttatcttt taaatccagt ttgatgaatt caggacggat acctgtgatc
     9841 ttttcaatgc catccaacac ttcgatattg gagtttgaca ggtcgtcgat gataacaaca
     9901 tcataacctg cattctgcaa ctcaactgta gtgtgtgagc caatatatcc ggttccacct
     9961 gctactaaga ttttcttttt catgctagtc tctatttaga ttaaattata cgattccgga
    10021 gaatcccata aacgccattg ccagtaaacc ggctgttatc agcgcaatag gggtaccttt
    10081 cataccttcg ggaacacgtg tcaaagccan nnnnnnnnng ttctcttatc cctgcaaaga
    10141 taactaaagc tagcgcaaat ccaatagctg ttgatattgc atatacaaca gattctaata
    10201 aattatattc tttttgtatt acgaggatgg cgacacccaa aatacagcag ttggtggtga
    10261 tcagcggaag aaacacgcca agtgcctggt aaagagccgg agaaaccttt ttcagaatga
    10321 tctcgaccat ctgaaccagt gcggcgatga tcaggataaa actgatggtc tgcataaagc
    10381 ccagtccgaa cttatccagg atatatttct gcaccaggaa agtaacgatg gttgcgatcg
    10441 tcaacacgaa tgttactgct gcacccatac cggctgccgt ttccaccttt ttcgatacgc
    10501 ccaggaacgg acagataccc aggaactgcg ccaacactac gttgttgacg aatacggctg
    10561 cgataaatat tagtatatat tccatatctt tcgtttttta atatcaggct ttacgcaatt
    10621 tattaacaat agcaatcagg taacccagcg cgataaaggc acccggagcc aatacaaaga
    10681 tcagcgaacc atattgttcg ggcatcagtg tcaggccgaa cagtttacct gttcccagca
    10741 gttcgcgggt agctccgagc aaggtaagtg ccagcgtaaa gccgagtccc atacctaatc
    10801 cgtcgaaagc ggaaggaatc acaccgtttt tagcggcaaa tgcttccgca cgtcccagca
    10861 caatgcagtt tacaacaatc aacgggatga acaatcccag gctggcgtaa agagccggaa
    10921 cgaatgcttc catgcacatc tgcacgacgg ttacgaatgt tgcgattacg acaataaagg
    10981 ccggaatacg taccatgtcg gggatcaggt tcttcaaggc tgaaataacc atattggaac
    11041 agatcagaac gaacatggtt gccagtccca tactcatacc gttcaatgct gaagaagttg
    11101 ttcccagagt tggacacata cccagcaaca agacaaatgt cgggttctct ttgatgatac
    11161 cgttcatcaa tactttcata ttactcattg tcgtttcctc cctcgttagt gttagcggtt
    11221 gttgcaccgg ttactccgtc agttccggcg aatgcgctgt aagcacggtt caccgcatcc
    11281 agaaatgcac ggctggtgat ggttgctgct gtgatagcat ccacgttgcc accgtcttta
    11341 gttactttta atggtccggt ggacaggctg cgtcccaaaa cgctttgttt attcttgtcc
    11401 gtactgaacc attcctgcat tttagctccc agaccgggag tttccgcatg ctgtaatacg
    11461 gaatagttca ataacttgcc ttccttatcg aatccgacga tcactttgat ctctccgctg
    11521 aatccttttt ttgtattact ttcgacagct gcacctacga actctccgcc tttggtagcc
    11581 ggatagattt tcagggaatc gccgtcgcct gtaactgcca tataagcgtc ctctgacggt
    11641 ttgttgtcga attcaggtgt aacagctttg atagcagctt ccagcgcagc agctttggag
    11701 gctgcaatcg ggccggtggt gtacatattt actccggcta atatcgctcc cgcaaccaaa
    11761 cagatgatgg taagcgacaa gagcatattg ggtaatgttg attttagttt tgccatgctt
    11821 atttccctcc aaaatgttta ggtttgatat aactgttgat cagcggggta aatgcattca
    11881 taataagaat agcaaacgac ataccttccg gataagaacc aaacagacgg ataacggtag
    11941 tcagaatacc gataccgaca ccgtaaacca acataccgtt cttactcatg ggcgaagtca
    12001 catagtcggt tgccataaag atggctccca gcatcagacc tcccgacagc aggtgaacga
    12061 atggacttgc gtattgtacc ggattaacca ggtgcataat acctgtgaat acaaatacgg
    12121 tcagcaggat agaaaccgga atctgccagg taataatctt tttccataac ataaagacga
    12181 gtcccagcag caatgccagt gcacttactt caccaaggct gccgcccatt ttacctaaca
    12241 acatatctac cagggtaggc aacttgtcga gtgccccttc gttcatcagt gataaaacag
    12301 ttgcaccggt ggttgcgtcg gtgtacgctg tcagctgtcc gacttccggc cacatcgtca
    12361 tctgtgccgg gaaagagatc agcaggaata cacgtccgac taatgccggg ttaaaaatat
    12421 tgttacccag tccgccaaat gacatcttac cgataccgat tgctgccagt gcaccgatca
    12481 ggatgatcca tacaggcagg ttcgacggca ggttgaatgc cagcagtaca ccggtcagga
    12541 tagccgaacc gtcacatacg gtcggttcct ttttcatcag gaacttctgg atcagatatt
    12601 caaagaggac gcaggctacg accgatgttg cagtaacgat cagcgcaccc agcccgaagt
    12661 agtagaggga taccaggaaa gccggaacaa gggcaatcag tacaccatac atatttttgc
    12721 ttatgctatc gccgccgtgg atatggggcg aaggagatac tattaaatta ttttccatat
    12781 tgctctgttt ttatgacttt cgtgcccgta tgatacccat tacctttcct ttacccgaac
    12841 ggatataatc cagcaacgga cggttggccg ggcaggtata actacaagaa ccgcactcga
    12901 tacagtcggt gatataattc ttctcggcca aatcccattc tgcaaattct gttgcattca
    12961 tcagcagggt agggttgagg cccatcggac aaacgctgac acatttggca cagcggatac
    13021 agtcgcgcat cggtttgcgg acagactctt cttttgtcag gagcaatacg cctgaactac
    13081 ctttcgttac cggtacttcc ggagcaatca gggcttttcc catcatcggg ccgccaccga
    13141 ttatctttcc tgtattttca ggaacaccac cggcagcttc aatcagtgca ctgataggcg
    13201 tacccatacg gaccaggaag ttggaaggat tggtaactgc tttacctgtc acggtaacga
    13261 cgcgttcaaa caaaggtttg tttttcatta ccgcttcata cactgcaaaa gcagttccta
    13321 cattttgtac tacagctccg gcggaaatag gcagtgcacc gctcttcacc tgacggcgaa
    13381 tcacagcatc gattaattgc ttttcacctc cttgcggata ctgtactttc agcggcataa
    13441 tctcgatacc tttataggct gtagccagtt tactcagatg agcgatggcg tcaggcttgt
    13501 tgttttcgat accgatcact gcttttgtta catttacagc tttcatcaac agcgtaacgc
    13561 cgaccagaat ctgctctgcc ttctccatca tcaatgaatg gtcggaagtc agatacggct
    13621 cacattctac ggcattgata atgatgatct cggctttgct tccgggaggc ggcatcagtt
    13681 tgacctgtgt ggggaatgtc gcaccaccca gacccacgat accggctgcg gcgatcttgt
    13741 ctacgatctc tttggaagga agcgggcact ctttcacgag cgtttcgctg cggtcgatcg
    13801 actcttccca ttcgtcacct tccacatcaa tatagatagc gggacgtttg tatccgcttg
    13861 cgtcgagagc gttatctatc ttgtttactt taccggatac cgacgagtgg atattcgccg
    13921 atacaaaacc tccggctttg gcgagaagcg tacctacttt aaccgtatca cccttcttta
    13981 ccacagcctg ggcaggagcc ccgatatgct ggcttagcgg tataataacc tgcttgggta
    14041 tagccagtcc ggttattttc ttcccggcag acaatttatt ttcgggtgga tgtatacctc
    14101 cgattcgaaa tgtccttagc atactattag atttttattt ttgagttgtt tcttcttttg
    14161 ttattgtttc aggcgctgtt gccggtgcag cttcgacttt tgtcggtgct tcggctttag
    14221 gggtcgatgc agctttaggc gttactggct ttactttgtc ggcgtccaca gcaggggcgg
    14281 cttctttacg gggcgggaag ttcaattcgt gaattgctcc ggtcggacat actgctacgc
    14341 atttacggca cagacggcat ttgcggtagt cgatataagc cacgttgttt tcgagcgtaa
    14401 ttgcttcgaa cggacattct ttcacacatt taccacaacc gatacaagcg ttcgcacatg
    14461 ctttacgggc agcagctcct ttgtctttgt ttacacagct gacgaagata cggcgtgatt
    14521 tcggtccctt tttgcgcagt tcgataatgt ttttcggaca agctttgacg caggctccgc
    14581 atgaagtaca tttgtcctcg tccacttccg gcagtccggt tgtcggattg acgtggatgg
    14641 cgtcgaaggt acaggcactt tcgcagtcgc cgtaacccag gcaaccgaac gtacagttcg
    14701 tttcgcctcc gtacaaagag gatgctatgg tacagctttt tacgccatca tactggttgg
    14761 tgcgcggacg ggcctggcag
//
