LOCUS       gnlProkkaKEJNEGFI_7    14868 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KEJNEGFI_7.
ACCESSION   gnlProkkaKEJNEGFI_7
VERSION     gnlProkkaKEJNEGFI_7
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 20:58:27
            Original ID  :: gnl|Prokka|KEJNEGFI_7
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 137100
            Orig. end    :: 151968
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14868
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[10000:10900]"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10900
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..14868
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14868
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene"
                     /region_number="1"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /tool="antismash"
     CDS             complement(702..1334)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 144.6; E-value:
                     6.6e-44)"
                     /gene_kind="transport"
                     /locus_tag="ctg7_153"
                     /transl_table=11
                     /translation="MKLLCESVCFSYSGKQWIFEDYNRVFTSGITILKGYSGCGKTTLL
                     KILAGYLKPQSGRVVTPRRKVPADSLYRRKEVSYMFQGLNLLPLATVERNLQLCAEMAM
                     LPKKQWTRRADDLITRLGLESLRHKKAGSLSGGQAQRAALARTMMKDSDVLLLDEPTSG
                     LDDGNTEIIKNLIREYPADKICILSTHDSRLFDLTHEIMDFNLSVSL"
     CDS             complement(1331..2434)
                     /locus_tag="ctg7_154"
                     /transl_table=11
                     /translation="MTGLCCREMEAGLFEIMVGRAKKCLWGIWLCSGLALCVWNAESAG
                     GGTGMAASEDACFIKTFRAKIVPERLRSFVMPADGIVSNWIPADGRVQKDTIIATVNED
                     EIELERKELEVKILKDRIAKEEELSKLEKQLEEIEFYSSLTREERQYASKQAEGGERAI
                     RALKDKIELSKKELSLVEDKPRLDFRKKEEKYILRMPFDGKLQYQFSIPPDNSVALYMD
                     AASPIATVCDDSSYYLTISISDPDLTNLPPESLSLSVPLGDGSALKGVFAFKRVEKNVS
                     GGGELLAYFFRLPRQEHARAHSMLGSNCTARLYYMPQGEVFHLNKVRLASLPEGKKCSS
                     WQELLEKVHPDLELVVNGETELIVRKK"
     CDS             complement(2448..3002)
                     /locus_tag="ctg7_155"
                     /transl_table=11
                     /translation="MFSRLTNRCVLSSLSAAALSLGLFSCGGSGSSGDGESLPSGTMLD
                     LSASLSTEDGLGPWNIIVKLTGNGSDLPQVSINAASSNESAPMNIASVVYRRTGSSAIL
                     RGNFTITSGQWTAPGPIVVTNRDKAFIDANISFNTSNERESCGGTFTGSITYQVPVQND
                     EGGFEAQDWTATEGTVSYTVS"
     CDS             complement(3201..6737)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 133.6; E-value:
                     1.5e-40)"
                     /gene_kind="transport"
                     /locus_tag="ctg7_156"
                     /transl_table=11
                     /translation="MIQWFFDIPSKLIHWRLNLVRTLGAYVPWLRRDDGSMKVHAGTLV
                     DLFATILSGRRHLSARDADAALDILRYTFPEVEHRWLSNRFERSMRASLTVADVLASAA
                     SGRDETERMAIALEVLSLLINTGDARMTGDLFDQVTYGLELPGTANHLRQLLMTPDVEA
                     QEPAYSVGFSSGIGAEVSLPEQDKGISFRLIRCSRLVLVVNDGTRPIVVRGRHLQPGGV
                     MPLTNGQVVLLPSGPLSFEDFAFFLDCKRSGKQDVCYISLDGGSLQISRVRSRASEVRV
                     NMGLACEVEVLRPEVEFAVDGKRLYPGESVRMAYYSSFTLDGEGPFSMGEVQNSMSDIG
                     RRFRLDPGNRKLRVTNLPEKARKGDMLLTPGLAPGAVLEVSFSSATNSGWLEVVEASMP
                     LLLNGRPVRGRVSLRDGDVVHLNAYHALRCRFSAGVLDEEYHAIRTLSVEGVTKEFLRS
                     GRVLDNIDLAVKRGEMVCILGPSGSGKSTLLSMLAGQLPPTRGCIRYNNQLLYSAPDLI
                     RPYIAFIPREDILDAAMSVSEHISQATMIRRPRLNRSERVRRVNAILKFLGLTHIASRR
                     VGEMNARTISDGERTRLNLGLDLAGIADVFLLDEPISGLSTSDAKLVMQTMQNMSRDKM
                     VIATMHRPSTAILNQFHKVLVLDHGGQMAYWGDVPGMMRYFRKAAADMAIDVSEEARTA
                     GGADYVFEVLEAPLSWHDRRRRQHPRLWQERFEGYRFRNVMGHHHEGGAPRTLYEGTLE
                     FPPAPRRSVIQLWRLFRIWAVRTFLGRVRSRMGLYTMLLEGPVLALLISMTLRASSSPE
                     YTFATALHIPSYLFLATIVAMFFGLTGAASEVLKDRALLKRESNAKVFVTGYVLAKALV
                     LTGLSAVQSALFLWVGNSILEIHEMFLIYLGTMTLTAFVGVSLSLLVSVFARTERAALN
                     MVPLLLIPQILMAGAIVRFDEMNQFIPWSAHRTDEHGRLKPGRVPLVAEFCPLRYSFET
                     MVVDQASKNVWERERETIQEKVDDLKERPHLDDREFEEFKLLKMALLHIAAIGAEGPEQ
                     AKAAVRQVRRAALGGSEKSYRRTIAELELLGKGRPSVKSFYVNDRVVMLDESAEIQRVS
                     RDALDRPEIFLARRQPLPWGGSGLSPGDSGYSADDGTVPTPWKDSLFLFLMGAAPLLVT
                     GRVLKRRLEKAG"
     CDS             6930..7352
                     /locus_tag="ctg7_157"
                     /transl_table=11
                     /translation="MDILVSTLCDFAADYQGKLCIQGGFDSLVARQFPVVHPVCAVALR
                     ICLTPEDEGTHELGLSIVDADGTPLDKERMPIKINFPVPAFPEGASFFTRNLIMNFQGL
                     RFEKPGNYSIDLTVDGELASRVPFRVVQVQEEAAQA"
     CDS             7586..8431
                     /NRPS_PKS="Domain: PKS_KR (11-174). E-value: 1e-13. Score:
                     43.4. Matches aSDomain: nrpspksdomains_ctg7_158_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     164.2; E-value: 6.5e-50)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_158"
                     /sec_met_domain="adh_short (E-value: 2.4e-32, bitscore:
                     105.7, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYTARLQYDRIIITGASSGFGEAFAGTLAPHTAELVLIARNEAAL
                     RQLAAALEKRHPGLHASVLPCDLADETSLNTLISRLDSLPPGRTLLINNAGAGDYGDFA
                     DGRWEKIRSLLRLNVESLTRLCHALIPVMKRNGGDIINLSSLGALLPIPDFAVYAATKA
                     YVSSLSEALRLELREHGIRVMAVCPGPVSTGFGKAARRPGFTGNMMPGRNAFDTSVETV
                     VKDSLRALARGRARVFPGMKIRLAAMLLAAAPLGLIRLFMGRRPRKVLPASNDSPSSAS
                     "
     aSDomain        7619..8107
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg7_158_PKS_KR.1"
                     /evalue="1.00E-13"
                     /label="ctg7_158_PKS_KR.1"
                     /locus_tag="ctg7_158"
                     /protein_end="174"
                     /protein_start="11"
                     /score="43.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="IITGASSGFGEAFAGTLAPHTAELVLIARNEAALRQLAAALEKRH
                     PGLHASVLPCDLADETSLNTLISRLDSLPPGRTLLINNAGAGDYGDFADGRWEKIRSLL
                     RLNVESLTRLCHALIPVMKRNGGDIINLSSLGALLPIPDFAVYAATKAYVSSLSEALRL
                     "
     CDS             8428..9999
                     /locus_tag="ctg7_159"
                     /transl_table=11
                     /translation="MKAHRRGIPRLTWFKLAVCLCLAAMAVSLFTPYPAQIIRALKGEP
                     EQAPPDSGTCPPQESPPAEQPGQEEQPITAAPSASGKEPGDERLYTPWTPERTIALPPV
                     QYPPFPPVLPTRPAEGAMTHIYELARGLNLKTQVNFQPGTLASRDRETKSNYQMTLSLN
                     VKQPKALTKKEDILKLNPKLEPMLPGLSTLFRHARVSPYYGQVYVRKQTEIRKNLASLL
                     KLLDRHNYYDTETILETAYPDTGRKLLWLQSEMDVVSDGSDGDRLAAMPDKILKSSFYQ
                     PSTSYRWKKRTDKPNPLLNPWQQRLASYKKTLEKAPAAEKTALRRKIDHAERVIEELKR
                     YSFLISEYDPFIVVPLGVVNQSSPFSPQFGDYAVVIVGDKLYPALVGDAGPRYKTGEGS
                     LRLSREINPKAGPYSRPVSDLKVSYLIFPGSAEPEAGPPDYEKLTDRCRELLNEIGGMG
                     KGFKLHQWEDLLAPKPPPAPKPESGGTAETSADKRKKEEAPGNKPAPAPASPQTAPASS
                     AAKSAA"
     CDS             complement(10001..10900)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_160"
                     /sec_met_domain="phytoene_synt (E-value: 8.8e-17, bitscore:
                     54.5, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGLDHLLSAVSRSFYLSMRFLPREMRPGVAVGYLLARATDTVAD
                     AVDMDCRERLALLRMMGETVAGSASREVAATCFGRLGVLSTIQTHRGEAELLARFPECL
                     ALLENLSPHERMLVRQVLASIVEGQAWDLRYFESHAAVSCPEQLEHYTYMVAGCVGEFW
                     TRLGLLAQGPGFSTQPEGQLLRWGRHYGMGLQLVNILRDREEDLARGRSYLPAPDDRPW
                     LDRAERWLKEGVFYAESLRNGRLRFSTVLPAWLGLDTLELLQRADRRHPSSGKVKIARG
                     DVYLRMWKAFLFSWKEAL"
     CDS             complement(10897..12390)
                     /gene_functions="regulatory (smcogs) SMCOG1112:sigma-54
                     dependent trancsriptional regulator (Score: 427.4; E-value:
                     1.2e-129)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg7_161"
                     /transl_table=11
                     /translation="MVVLKEISSAIVNERNGTALLRHILDVLYRRMKMLRGTFTIRRGN
                     DLMIEASHGLDEQEMKRGHYHVGEGITGHVAETGRPHVIEDISRDSRFLNRTRTRKSGE
                     KVAFICVPIIHLQQVIGTLSIDRAVDRDTDLERDQKLLEIVGNIVGDALAASLQAHEEH
                     AALVAENEKLRELLTTNPGELIGNCSTMLQVYEQIRQVAPSDATVLIRGSSGTGKELVA
                     RAVVNLSGRKDKPLVTLNCAAMPENLLESELFGHEKGSFTGATSRRIGRAEAADGGTLF
                     LDEIGDLSLQMQVKLLRFLQEKTFSRVGSNRELHADVRFIAATSRNLEELMAANKFRED
                     LYYRLNIFPIVMPDLSKRKGDVMLLAEHFLSKFNLKYGKDIKRLSTPAINMLMAYHWPG
                     NVRELENCMERAVITAQDDCIYGYNLPASLQMPSHDVPYSRDGEAPADLPTMVDSFERE
                     LIVAALKRSPGNMSAAARELGISPRVLHYKMHRLGLQKS"
     CDS             complement(12621..14408)
                     /locus_tag="ctg7_162"
                     /transl_table=11
                     /translation="MNSPSPQSQPPDSVWYGWILKLFHHWKVGERQVTYVWAVLVGVVG
                     SCMSLFFEWMVEVIQWMLTGIWSDSRVGTFSLVEPEWRMFIPVAGGLVAGCILLFLKKR
                     MPGQATEYMEAMSIGNGLIKFRASALKVFSAAWSIASGAAIGKEGPIIQSSALIASTVG
                     QRLHVSIPRLRLLVGCGAAAGFTTAFHAPFSGCLFVSEIIIGTVSMDILAPLLIASCTG
                     FVMLHLLGDPSPLYSSPFESFTVFSQSLWCIALGAAAAVAARGWVSLLDAAARYLNGRQ
                     SLLPLRLAAAGLVVGILAVFYPEVVGNGQALITGLVHEDYGTREALVLLLVKVSAVAVV
                     FGCGTVGGAMTPTLYVGSMVGFIFSTVLTSLGMEGNHTVAYAMVGMASFFAVAAQAPLT
                     ALVMVVEFSMSGQMIYPLLIGVVSAYGTGKLIRARSMYAASLAGSPASVVSLPMAQVHV
                     HDLARHVVPQVAPDASLDDVSSLMLRNPGDLVFVVNKDGTYEGAIYPEDFLAVRRQMEE
                     RKGAAPADAGSLVRTGAPVLDAGTHLTDALKLFEQTHLPAFPVVWKNTGRLDGVLYRNA
                     LFQVITEMMKRESGGDVGM"
     CDS             complement(14578..14868)
                     /locus_tag="ctg7_163"
                     /transl_table=11
                     /translation="MHTFRGYYAVFAGMHEEIADCVRVDAVVRYGYNGGYVGPVVHHGS
                     NALDYNLSVTFRATGRLTVELFTNYSQALTVVKQKGLGDDFYYGVNLKYTF"
ORIGIN
        1 cttccagcct gtcaagcagc cctacgtgag tctgaaccat ggtcatgctg ccgtcataac
       61 gcaccatgtt gttcagcact tcttctatgt cccgaatgcg ggccgccgtc atttcatgca
      121 cccggatgat gtagcggcaa ttttccacgg gaacctcctg tccggaactg aaggttcctt
      181 ccggggccaa aatgactccg gaaggataca gcctgcccag caaatgcccc tccggcagag
      241 gggaggcatt cagggaaaaa tcaaaatccg ctatggtaac cgtacaaggc cccgcctgca
      301 acgggctccg ggagggattg tacaggagga cggtagccac atcctccaac ccaagcgcgg
      361 aaagaaagga acaggactcc atgttgtatt ccaggatggg gaatactgtc ttgcccacgc
      421 gcgccacgcc cgcacgggca tcattcagca ccaggacgtc gcagccatac agggaaggca
      481 gttcatgctg cagcaaattt ttcttggaag gctcaccgtc gcgcacggta tcaaaaacaa
      541 taatcaggtc cgccccgttc ttcctgattt catcatgcag cattttggcg gagaggacat
      601 aattggcgag aaaagagagc gcgcacaggg aaaggaagaa ggccaccaga atccgtgaaa
      661 gggggctggc cgggcgttcc ttccaacggt ggagagtatc tttaaagaga tacagacagg
      721 ttaaaatcca tgatttcatg agtcaggtca aacagccggg aatcatgcgt gctcaaaatg
      781 caaattttgt cagcagggta ctccctgatc aaatttttaa tgatttccgt attgccgtca
      841 tccaagccgg aagtaggttc gtccagcagc agcacatcgg aatccttcat catcgtgcgg
      901 gcaagagccg cccgctgggc ctggccgccg gacaagctcc ccgccttttt atgcctcaga
      961 gattccaggc ccaggcgggt aatcaaatca tccgccctcc gcgtccactg ctttttaggc
     1021 agcatggcca tttccgcgca caattgaagg tttctctcca ccgtagccag gggaaggaga
     1081 ttaagcccct ggaacatgta gctcacctcc ttgcgccggt agagggaatc cgccgggacc
     1141 ttccggcggg gagtaaccac gcgcccgctc tgcggcttca gataccccgc cagaattttc
     1201 aacagagtcg ttttcccgca tccggaatac cctttcaaaa tggtgattcc ggaagtgaat
     1261 accctgttat aatcttcaaa aatccactgc ttgcctgaat aactgaaaca gactgattcg
     1321 cacagcaatt tcattttttt cgaacaatca attccgtttc tccattcacc accagctcca
     1381 ggtccggatg cactttttca agaagttcct gccaggacga acattttttc ccttccggca
     1441 gggaagccag cctcaccttg ttgagatgaa acacttctcc ctgcggcatg taataaagac
     1501 gggccgtgca gttggaaccc agcatcgaat gggcgcgtgc atgctcctga cggggcagac
     1561 ggaaaaaata cgccagcaat tccccgccgc cggaaacatt cttctccacc cgcttgaagg
     1621 caaaaacccc cttcagggcg gaaccgtcgc ccagagggac ggacagggaa agggattccg
     1681 gcggcagatt cgtcaaatca gggtccgaaa tggaaatggt cagataataa gaggagtcat
     1741 cgcacacggt cgcaatcggg gacgcggcat ccatgtacag ggctacgctg ttatccggcg
     1801 gaatggaaaa ctggtactgc agtttcccgt caaaaggcat tctgaggata tatttttcct
     1861 ctttcttgcg aaaatccaga cgcggcttgt cttccaccag ggacaactcc tttttagaaa
     1921 gctcaatctt gtctttcaat gcccggatgg ccctttcccc gccttccgcc tgcttgctgg
     1981 catattgccg ttcctccctc gtcagggaag agtaaaactc tatctcttca agctgttttt
     2041 ccagctttga caactcttcc tctttggcga tgcggtcctt cagaattttt acttccagct
     2101 ccttgcgctc cagttcaatt tcatcttcat tgactgttgc aataatagta tccttctgaa
     2161 cgcgcccgtc cgcgggaatc cagttgctga caattccatc cgccggcatg acaaaggaac
     2221 gcagcctctc cgggacaatc ttggcgcgga aagtcttgat aaagcaggca tcttccgatg
     2281 ccgccatacc agtccccccg ccggccgatt ccgcattcca gacacaaaga gccagccccg
     2341 agcacagcca gatgccccaa agacatttct ttgcccttcc gaccataatt tcaaacaggc
     2401 ctgcctccat ttcacggcag caaagccccg tcataaatga tcagaactca ggataccgtg
     2461 taactcaccg ttccttccgt agcggtccag tcctgcgctt caaatccgcc ttcatcattc
     2521 tgaacgggaa cctggtaagt gatggaaccg gtgaacgtcc cgccgcagct ctcacgttca
     2581 ttggaggtgt tgaaggaaat attagcatct ataaaggcct tgtccctgtt tgtcacgaca
     2641 atcgggcccg gagccgtcca ctgcccggaa gtaatcgtga agttccccct cagaatagcg
     2701 gatgatcccg tcctgcggta cactacggaa gcaatgttca taggagcgct ttcattgctg
     2761 cttgccgcgt taatgcttac ctggggaagg tccgaaccat tgcccgtcaa tttgacgata
     2821 atattccacg gccctagccc atcttccgtg gaaagagaag cgctcaagtc cagcatggtg
     2881 ccggaaggaa ggctttcccc gtcaccgctg ctgccgctgc ctccgcagga aaagagtcca
     2941 agggacaaag ctgccgcgga aagggaagat aatacgcacc tgttcgtcaa tcgggaaaac
     3001 ataaagaaaa agattttctt caaggatagt gattccgtcc ggcgcgtcaa cacataaata
     3061 aaagaatatt tggaggggcc ttccgttttt ttgcgggatg caccggggct tacggcccgc
     3121 tgccattccc cggacgcgca cgccggattt tccgctttgc ggcggaaaat ccagacgcca
     3181 atccccgcag gccgcaaacg tcatccggcc ttttccagcc tgcgcttgag gacgcggccc
     3241 gtgaccagca ggggggcagc ccccatcagg aacaggaaca gggaatcctt ccatggggtg
     3301 ggaaccgttc cgtcatcagc gctgtatccg gaatcccccg gggacaggcc ggagcctccc
     3361 cagggcagag gctggcggcg ggccagaaaa atttccggcc tgtccagggc atcccggctg
     3421 acacgctgga tttcggcaga ttcatccagc atcacaacgc ggtcattgac atagaaggat
     3481 ttgacggacg gacggccctt gcccaggagt tccaattccg caatagtccg cctgtagctt
     3541 ttttccgaac cgccaagggc ggccctcctc acctgccgga cagcggcttt ggcctgttcc
     3601 ggcccctccg ctccaatagc ggcaatgtgg agcagcgcca tcttgagcag cttgaattct
     3661 tcaaattccc tgtcgtccag atgagggcgt tccttcaggt cgtccacttt ctcctggatg
     3721 gtttcacgct ccctctccca tacatttttg gacgcctggt ccaccaccat cgtttcaaaa
     3781 gagtagcgca aagggcagaa ttccgccacc agcggcacac gccccggctt aagacgcccg
     3841 tgttcatccg tacggtgggc ggaccatggg atgaactggt tcatttcatc aaagcggaca
     3901 atggctccgg ccatcaatat ctggggaatc agaagcagag gcaccatgtt aagcgccgcc
     3961 ctctccgtcc tggcgaagac ggaaaccagc agggacaggc tcacgccgac aaaggccgtc
     4021 agggtcatcg tccccaggta aatcaggaac atttcatgga tttccagaat ggagttcccc
     4081 acccaaagaa acagggcgga ctgcacggcg gaaagccccg tcaacaccag cgcctttgcc
     4141 agcacataac cggtcacaaa taccttggca ttgctctccc tcttgagcag ggcacggtcc
     4201 ttgagcactt cgctggccgc cccggtcagg ccgaagaaca tggccacaat ggtcgccagg
     4261 aacaggtagg aagggatgtg gagggccgtg gcaaacgtat attccgggct ggaagaggcg
     4321 cgcagggtca tggaaatcag cagggccagc accggccctt ccagcagcat ggtgtacagc
     4381 cccatacggc tccgcacgcg ccccaggaag gtgcgcacgg cccagatgcg gaaaagccgc
     4441 cagagctgta tgacgctgcg cctgggggcg gggggaaatt ccagcgtgcc ttcatacagc
     4501 gttctggggg cgcccccttc atgatgatgc cccatcacgt tgcggaaccg gtagccttca
     4561 aagcgctcct gccacaagcg ggggtgctgc cgcctgcggc ggtcgtgcca ggagaggggg
     4621 gcttccagca cctcaaatac gtagtccgcg cctccggccg tccgcgcctc ctcggagacg
     4681 tcaatggcca tgtccgcagc cgccttccgg aaataccgca tcatgcccgg cacgtccccc
     4741 cagtaagcca tctggccgcc gtggtccagc accagcactt tgtggaactg gttcagaata
     4801 gccgtgctgg gccggtgcat ggtggcgatt accattttgt cgcggctcat gttctgcatg
     4861 gtctgcatga ccagcttggc atctgacgtg gacaggccgc tgataggttc gtccagcagg
     4921 aaaacatccg caatgcctgc caggtcaagc cccaggttca ggcgagtgcg ctccccgtcg
     4981 gaaatggtgc gggcgttcat ctcacccacg cggcgggagg cgatgtgcgt caggcccagg
     5041 aatttcaaaa tagcgttcac gcgcctgacg cgttccgacc ggttcagccg cggacggcgt
     5101 atcatggtgg cctgagagat gtgctcggaa acgctcatgg ccgcatccag aatatcttcc
     5161 cggggaatga aggcgatgta gggccggata agatccgggg cgctgtacag aagctggttg
     5221 ttgtaacgga tgcagccccg ggtgggcggc agctggccgg ccagcatgga gagcagcgtg
     5281 cttttcccgg atccgctggg ccccaggatg cacaccattt ccccgcgttt cacggccagg
     5341 tcaatattgt ccagcacgcg tccggagcgc aggaattcct tggtcacccc ttccacgctg
     5401 agggttctga tcgcatggta ttcttcatcc agcaccccgg cggaaaaacg gcagcgcagc
     5461 gcgtggtagg cattcaggtg caccacgtcc ccatccctca gggaaaccct tccccgaaca
     5521 ggccggccat tgagcagcag aggcatggag gcctccacca cttccagcca gccggaattg
     5581 gtggcgctgg aaaaagaaac ctccagcacc gctccggggg ccagcccggg agtcagcagc
     5641 atgtctccct tgcgcgcctt ttccggcagg ttggtcaccc gcagcttgcg gtttccggga
     5701 tccaggcgga aacggcgccc gatgtccgac atggaattct gcacctcccc catggagaaa
     5761 ggcccttccc cgtccagcgt gaaggatgag taataggcca tgcgcacgct ttcaccgggg
     5821 tacagccgtt tcccgtcaac cgcgaattcc acttccggcc tcagcacctc cacctcgcac
     5881 gccagcccca tgttcacgcg cacctcgctg gcgcgggaac gcacccggct gatttgcagg
     5941 gagcctccgt ccagggaaat atagcataca tcctgcttgc ctgaacgctt gcaatccaga
     6001 aaaaacgcaa agtcttcaaa actcagcgga ccggacggca gaagcaccac ctgcccgttg
     6061 gtcaacggca tcaccccgcc gggctgcaaa tggcgcccgc gcactacaat ggggcgggtg
     6121 ccgtcattca ccaccagcac caggcgggaa caccggatca ggcggaagga aatgcccttg
     6181 tcctgctccg ggagggatac ctctgcaccg atgccggagg aaaaaccgac gctgtacgcc
     6241 ggttcctggg cctccacgtc cggtgtcatc agcagctgcc tcaggtggtt tgccgtgccc
     6301 ggcagttcca gaccgtacgt cacctggtca aacagatccc ctgtcatgcg ggcatctccc
     6361 gtattgatca gcagggagag cacttccaga gctatcgcca tgcgttccgt ctcatccctg
     6421 ccggaagctg cggaggccag gacatccgca accgtcaggc tggccctcat ggaccgctca
     6481 aaacggttgg aaagccagcg gtgctccact tccgggaaag tatagcgcag aatatccaga
     6541 gcggcgtccg catcacgggc gctcaaatgg cggcgtccgc ttaaaatagt ggcgaacaag
     6601 tccaccagcg ttccggcatg caccttcatg gagccgtcgt cacggcgcag ccacggcacg
     6661 taggcgccca gcgtcctgac cagattcagc ctccagtgaa tcagcttgga aggaatgtca
     6721 aaaaaccatt ggatcatgcc aggaaacgcg ttgccggaac cagtagtaca gggattcccg
     6781 ccccatctca agcgcaaccg gaatttcacg gagaaatgac aatattttct acagctttat
     6841 cttgcaatag gtccggagga agtatagttc tgtccaatgt tcatgctttc cgcgtgaaag
     6901 ctagccaaat acatcaacat tatcacaaca tggatatttt agtttctact ctttgtgact
     6961 tcgccgccga ctaccagggc aagctctgca tccagggcgg ttttgactcc ctggttgccc
     7021 gccagttccc agtcgtgcat cccgtctgcg ccgttgccct gcgcatctgc ctcactcctg
     7081 aagacgaagg cacgcacgaa ctgggcctga gcatcgttga tgccgacggc acgccgctgg
     7141 acaaggaacg catgcccatc aagatcaatt tcccggttcc cgctttcccg gaaggagcct
     7201 ctttcttcac ccgcaacctg atcatgaact tccagggcct gcgttttgaa aaaccgggca
     7261 actactccat cgacctgacg gttgacggcg agctcgcctc ccgcgtgcct ttccgcgtgg
     7321 ttcaggttca ggaagaagcc gcacaggctt aagcaacctc ccctttccat caaaccgcct
     7381 accgttcatc cggcaggcgg ttttttattg gagcggccgt cctcccggaa gtgcggaaca
     7441 ggccggcccc ggttccatgc acctgaagac ctctgcgcct ggccccggcc taaaaaaggg
     7501 aggccggctt tttgcgtcct ccttccccct ttttcattgc ggttccgcac cggattgacc
     7561 atgatacggg ctgctccaac ccgccatgta caccgcacgc ctccaatacg acaggattat
     7621 cattacgggc gcatcatccg gcttcgggga agcgtttgcc ggaacgctgg ccccccatac
     7681 ggcggaactg gtgctcatcg cccggaatga agcagccctg cgccagcttg ccgccgccct
     7741 ggaaaaacgc catcccggcc ttcacgcctc cgtccttccc tgcgacctgg cggacgaaac
     7801 ctccctgaat acgctcattt cacgcctgga cagccttcct ccgggaagaa cccttctgat
     7861 taacaacgcc ggagccggtg attacggaga ttttgcggac ggccgctggg aaaaaatacg
     7921 ttccttgctg cgtctgaacg tggaaagcct cacccgcctg tgccatgcgc tgatccccgt
     7981 catgaagagg aacggagggg atatcatcaa cctcagttcc ctgggagccc tcctgcccat
     8041 tccggatttt gccgtctatg cggccaccaa ggcttatgtt tccagcctgt cggaagcgct
     8101 gcggctggaa ctgcgcgaac acggcatccg cgtgatggcc gtctgccccg gcccggtttc
     8161 cacaggcttc gggaaagcgg cgcgccgccc cggcttcacc ggaaacatga tgccggggcg
     8221 caatgctttt gacacgtccg ttgaaaccgt cgtgaaagac agcctccgcg ccctggcccg
     8281 cggacgagcc cgggtctttc ccggcatgaa aatacggctg gccgccatgc tgctggctgc
     8341 cgccccgctg gggctgatac gccttttcat gggcagacgt ccccggaaag tcctgccggc
     8401 atccaatgat tctccttctt cagcatcatg aaagcgcacc gccgcggaat accccgcctc
     8461 acctggttca agctcgcagt ctgcctctgc ctggcagcca tggctgtctc cctgttcacg
     8521 ccgtaccccg cccagatcat acgcgccctg aaaggggagc cggaacaggc gccgccggat
     8581 tccggaacct gtccgcccca ggaatccccc cccgcggaac agcccgggca ggaagaacag
     8641 ccaataaccg ctgcgccatc tgcctccgga aaggaacccg gggatgaacg gctgtacact
     8701 ccatggacgc cggagcgcac aatcgccctt cccccggtgc agtacccccc atttcctccc
     8761 gtgcttccca caaggcccgc ggaaggggcc atgacccata tttatgaact ggcccgcggc
     8821 ctgaacctga aaacgcaggt taatttccaa cccggcaccc tggcctccag ggacagggaa
     8881 accaaaagca attaccagat gaccctttcc ctgaacgtca aacagcccaa agcattgacg
     8941 aaaaaggaag acattctgaa gctcaatccg aaactggaac ccatgcttcc cggcctgtcc
     9001 accctgttca ggcatgcgcg cgtctcccct tattacgggc aggtttacgt ccgcaaacag
     9061 acggaaatcc gtaaaaacct ggcctccctg ctcaaacttc tggaccgcca taattattac
     9121 gatacggaga ccattctgga aaccgcctat ccggacacgg gaaggaagct tctctggctg
     9181 caaagtgaaa tggatgttgt ttccgacggc tcggacgggg accggctggc cgccatgccg
     9241 gataaaatcc tgaaaagctc cttctatcag cccagcactt cctaccgctg gaaaaagcgc
     9301 acagacaagc ccaatcccct gctcaacccc tggcagcaga ggctggcctc ctacaagaag
     9361 acgctggaaa aagcccccgc cgcggaaaaa acggctctgc gccgcaaaat agaccatgcg
     9421 gaacgggtca ttgaggaact gaagcggtac agcttcctga tctcggaata cgatccgttc
     9481 atcgtggttc cgctgggagt cgtcaaccag tcctctccct tctccccgca gttcggggac
     9541 tatgccgtcg tcatcgtggg agacaagttg tacccggccc tggtgggaga cgccgggccg
     9601 cgctacaaaa ctggggaggg gtccctgcgc ctgagccgtg aaatcaaccc caaggcgggc
     9661 ccttacagcc gccccgtctc cgacctgaag gtaagttacc tgatttttcc cggttccgca
     9721 gagcctgagg ccggcccacc cgactatgaa aaacttacgg acagatgccg ggaacttctc
     9781 aacgaaatag gcggcatggg gaaaggattc aaactccacc aatgggaaga cctgctggcg
     9841 cccaagccgc cgcccgcccc aaaaccggaa agcggcggca cagcggaaac atccgcggat
     9901 aagcggaaaa aggaggaagc ccccgggaac aagcccgcgc cggccccggc ttccccgcaa
     9961 actgcaccgg cttcatcagc cgcaaaaagc gccgcataag ctacagagcc tctttccagg
    10021 aaaaaagaaa ggctttccac atccgtaaat aaacgtctcc gcgcgcaatc ttcaccttcc
    10081 cggaagacgg atgccgccga tccgcccgct ggagcagttc cagcgtatcc agccccagcc
    10141 aggcgggcag gacggtggaa aaacgcagcc gcccgttccg cagagattcc gcgtagaaca
    10201 cgccttcctt cagccagcgt tccgcgcggt ccagccatgg acggtcatct ggggcgggca
    10261 aatagcttct tccgcgggcg aggtcttcct cccggtcacg caggatattc accaactgca
    10321 gccccatgcc atagtgcctg ccccagcgca aaagctgccc ctccggctgc gtgctgaagc
    10381 ccggcccctg ggccagcaag cccaacctgg tccagaattc ccctacgcat ccggccacca
    10441 tgtaagtata atgttccagc tgttccgggc atgagacggc agcatggctt tcaaaatacc
    10501 tcaaatccca cgcctgtccc tccacgatgg aggccagcac ctgccgcacc agcatccgtt
    10561 catgcgggga aaggttttcc agaagcgcca ggcattcggg aaaacgggcc agcaattccg
    10621 cctccccccg gtgcgtctgg attgtggaaa gaacgcccag acggccaaaa caggtggcgg
    10681 caacctcccg ggaggcagag ccggccaccg tctcccccat catcctcaaa agcgccaggc
    10741 gctcccggca atccatgtcc acggcatccg ccaccgtatc cgtggcacgc gccagcagat
    10801 agcccacggc cacgccgggg cgcatttccc ggggcaggaa gcgcatactc agataaaagg
    10861 accgggagac ggccgataga agatggtcaa ggcctttcat gatttctgca ggcccagcct
    10921 gtgcatctta taatggagta ctcgcgggga aatgcccagt tcccgggccg cggcggacat
    10981 attgcccgga gaacgtttca atgcggctac aatcaattcc cgttcaaagg aatctaccat
    11041 ggtcggcaaa tcggcaggag cctccccgtc acgggaataa gggacgtcat ggctgggcat
    11101 ctggagggag gcgggaaggt tgtaaccgta aatgcagtcg tcctgcgccg taatgacggc
    11161 acgttccatg cagttttcca gctcccggac gttgccgggc cagtggtaag ccatgagcat
    11221 gttgatggcg ggagtggaca gccgtttgat atcctttccg tatttcaggt tgaacttgga
    11281 aagaaaatgt tccgccagca gcatgacgtc ccccttgcgt ttggagaggt ccggcataac
    11341 gatggggaaa atgttcaacc ggtaatacaa gtcttcccgg aacttgttcg ccgccatcaa
    11401 ttcctccaga ttgcggctgg tggcggcgat gaagcgcacg tctgcatgaa gctccctgtt
    11461 gcttcccacg cgggaaaagg ttttttcctg aagaaagcgc agcagcttca cctgcatctg
    11521 aaggcttaaa tccccgattt catccagaaa cagggtgccg ccgtccgccg cctccgcccg
    11581 gccgatgcgg cggctggtgg ccccggtaaa agaacccttt tcatgaccga acagctcgct
    11641 ttccagcagg ttctccggca tggccgcaca attcagagtg accagcggct tatcctttct
    11701 gccgctcaga ttcaccacgg cgcgcgccac cagttccttc cccgttccgg aacttccccg
    11761 tatcagcacc gtggcatcgc tgggcgccac ctggcggatc tgttcataca cctggagcat
    11821 agtgctgcaa ttgccaatca attcgcccgg attagtcgtc aaaagctccc gcagtttttc
    11881 attttccgca accagggcgg catgttcctc atgcgcctgg aggctggcag ccagagcatc
    11941 cccaacaata ttgcctacaa tctccagcag tttctgatcc cgctccaagt cggtgtcccg
    12001 gtccacggca cggtcaatgc tcaacgtgcc gatgacctgc tgcaaatgaa tgatgggaac
    12061 gcagatgaag gctacttttt caccgctttt gcgcgtgcgg gtacggttca ggaacctgga
    12121 atcccgagaa atatcctcaa tcacatgggg cctgcccgtt tctgccacat gccccgtaat
    12181 gccttccccc acatggtaat ggccgcgttt catttcctgc tcgtccaggc cgtgggaggc
    12241 ttcaatcatc aaatcgttcc cgcggcggat ggtgaacgtg ccgcgcagca ttttcatgcg
    12301 gcggtaaagc acatccagaa tatgccggag caaagccgtg ccgttgcgtt cattgacaat
    12361 ggcggagctg atttctttca gcacgaccat ctccaaatcc ggtgacctgt ttatttcatt
    12421 catgcaatcc ggggctgggc gaatattaac cgcacgcccc cgccatacca actacttttt
    12481 cttccaccgc catgcagccg ggcaaaaaaa cggtacgggg aatatggata acatcccagc
    12541 aattaatttt gatgatatta cgaacgggga acaaaagatt tttacaaaaa tgtaatatac
    12601 atcccttgtt tcgttccgtt ttacatgccc acgtctccgc cggactcccg tttcatcatc
    12661 tccgtgataa cctggaacaa cgcgttgcgg tacagcacgc cgtccagccg accggtattc
    12721 ttccagacca cgggaaaggc tggcagatgg gtttgttcaa acagcttcaa ggcatccgtc
    12781 agatgggtgc cggcgtccag cacgggagcg cccgtacgga ccagggaccc ggcatcggcc
    12841 ggggccgccc ccttccgctc ctccatctgc cggcgaaccg ccagaaagtc ctccggatag
    12901 atggcccctt cataagttcc atccttattc accacaaaaa ccagatctcc gggattccgc
    12961 agcatcaggg aagagacatc atccagggaa gcatccgggg ccacctgggg caccacgtgc
    13021 cgcgccaggt catgcacatg gacttgcgcc atgggcagac tgacgacgga cgccggactg
    13081 ccggccaggc tggcggcata catggaacgc gcgcgaatca gttttcccgt gccataagcg
    13141 cttacgacac cgatcagcaa gggataaatc atctgtccgc tcatggaaaa ctccaccacc
    13201 atcaccagag ccgtcagggg ggcctgggca gctacggcga aaaaggacgc catacccacc
    13261 atcgcatacg ccaccgtatg gttgccctcc attcccagag acgtcagaac cgtactgaag
    13321 ataaaaccca ccatgctccc cacgtacagg gtgggcgtca tggctccccc caccgtgccg
    13381 cagccgaaca ccaccgccac ggcagacacc ttcaccagaa gcaggacgag cgcctcccgc
    13441 gtgccgtaat cctcatggac cagcccggta atgagagcct gaccgttgcc caccacttcc
    13501 ggataaaaaa cggccagaat ccccacgacc agcccggcgg ccgccaatcg cagcggcaga
    13561 agggactggc ggccattcaa atatctggcg gccgcatcca gcaaactgac ccatcccctg
    13621 gccgccacgg ccgccgccgc ccccagggcg atacaccaga gagactggga aaagacagta
    13681 aagctttcaa acggggaact gtacaaaggg gagggatccc ccagcagatg cagcatcacg
    13741 aacccggtac aggaggcgat aagcaggggg gctagaatat ccatgctcac ggtgccgatg
    13801 ataatttcac tcacgaacag gcagccggaa aaaggggcat ggaacgccgt cgtgaatccg
    13861 gctgccgctc cgcagccgac cagtagccgg agccgcggaa tggatacatg cagacgctgc
    13921 cccacggtag acgcaatcag ggcggaagac tggatgatag gcccttcctt gccgatggcc
    13981 gcgccggaag cgatgctcca tgccgcggaa aaaactttca gggcggaggc ccggaacttg
    14041 atcagcccgt tcccgatgga catggcctcc atatattccg tagcctgccc cggcatcctc
    14101 ttcttcagga acagcagtat gcagccggcc accaggccgc ccgccaccgg aataaacatg
    14161 cgccattccg gctctaccag ggaaaaggtg cctacgcggg aatccgacca gatgccggtg
    14221 agcatccact ggatcacttc caccatccac tcgaaaaaca gagacatgca ggagcccacc
    14281 acgccgacga gcacggccca tacataagta acctgccttt cccccacctt ccaatgatgg
    14341 aacagtttta aaatccatcc gtaccagacg gaatccggcg gctgggactg gggggacgga
    14401 gaattcatgg aaaagagggt aatactattt cattgtgaca aaaaaatacc tccggctgtt
    14461 cgatacggaa gaaaaaactg cccatcccca tgcccctccg gagccagaga agattttcaa
    14521 cggatacgca gacggctctt acgggccctc ttcggggcct ggcccccgcg ccggtagtca
    14581 gaacgtatat ttcaaattga cgccgtaata gaaatcatcc cccagcccct tttgctttac
    14641 cacggtcagc gcctggctgt aattggtgaa caattccaca gtcaggcgcc cggtagcacg
    14701 gaaggtaacg ctcagattat aatccagagc attggaacca tggtgcacca ccgggcctac
    14761 atacccccca ttgtaaccgt agcgcactac ggcatccacc cgcacgcaat cagctatttc
    14821 ttcatgcatc cccgcaaata cggcataata accgcggaac gtatggtt
//
