LOCUS       gnlProkkaCNLFLEBA_48   12420 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CNLFLEBA_48.
ACCESSION   gnlProkkaCNLFLEBA_48
VERSION     gnlProkkaCNLFLEBA_48
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 21:22:44
            Original ID  :: gnl|Prokka|CNLFLEBA_48
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12420
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..108
                     /locus_tag="ctg48_1"
                     /transl_table=11
                     /translation="MEIIKKLSLNYPKKNAYFADQIRFLEKLIINAKSK"
     protocluster    1..12420
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2207:2420]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2208..2420
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12420
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12420
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             113..502
                     /locus_tag="ctg48_2"
                     /transl_table=11
                     /translation="MYLLLVILMLIASVLMCFIVLIQNSKGGGLASGFSSSNQIMGVRK
                     TTDFLEKATWTLAAVMVVFSIVSAYTIPSSTGKGGDVILEQAQQEEKTNPYNMPVGTEA
                     PQSEAPAATTPAETPAPAAEAPAAE"
     CDS             656..2047
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 102; E-value: 4.6e-31)"
                     /gene_kind="transport"
                     /locus_tag="ctg48_3"
                     /transl_table=11
                     /translation="MTEQLKLKLNDSKATRWGALVIVAFTMMVAYYVNDVVAPLKTMLE
                     TDLAWSSTDFGFFTGGYSFLNVFFLMLIWGGLILDRFGIRFTGKLATILMVGGTALEYY
                     AMTGLAGADATLFGINEIFGYKTGVFVAFAGYSIFGVGAEVAGITVSKIIAKWFKGKEL
                     ATAMGVQVALARIGSQAGYAVAIPLARAFGISTPVLLGLVLLLGGMIAFFIFAVMDKKL
                     DKQMEAAAIAAGTEDEEEKFSFKDVKNILVNPGFWLIALLCVLFYSCVFPFQKFASELM
                     IIKYGINENVAGTFAGLPALGALILTPVFGGFIDKRGKSASIMLLGSAMLICVHFIYAI
                     PDINYWLVAIVLMIILGIAFSLVPSAMWPAVAKIFPVSQLGTAYALIFFIQNIGLWGIP
                     TLIGWVLDAYCISGKKPDGTNMYDYTVPMCIFTGIACLSLIVALLLKKADKKYGYKLEE
                     PNIQK"
     CDS             2208..2420
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg48_4"
                     /sec_met_domain="PqqD_RRE (E-value: 3.2e-10, bitscore:
                     30.8, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 2.4e-17, bitscore: 54.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKGMSPDIHVRLEEHGTAVWNLIDGHRTVREIISLLARHFGEEE
                     NYIPRVTAYVMQLRKDGFIQLTIRN"
     CDS             complement(2428..3396)
                     /locus_tag="ctg48_5"
                     /transl_table=11
                     /translation="MRGKDYGVTYMLPKTEIEIVLQATKHTYTPGEFCRYADRYLRLNN
                     VSAEPEEFWTLDKIETRIAGVPDKDNVYFVKMKDKTVAPLMELTEDGIVRSINIPFSGK
                     PAAKTPEAKATESSIDPRSFLTEEILMSNSSAKMAELVAKEIYSIRESKNALLRGEADN
                     MPKDGAQLKLMLDNLNQQETAMTEMFSGKIKKEPKTFTIRLTPKEMKDEVAFRFSRKLG
                     VVANNDLAGEPYYISVTDLKSPDVSATEEGKKKVDGVAYNLPGKAQVTLMYNNKKLFDD
                     QLPITQFGTVEYLAPVLFNKNSTIKVLFDTATGGLIKVDRE"
     CDS             complement(3548..4675)
                     /locus_tag="ctg48_6"
                     /transl_table=11
                     /translation="MKTLLFCMLGLGLTACGSSPKGTNGDQDELAMLIGTYTNGSSKGI
                     YTFRFNQETGTAVPLSSAALPNPSYLVPSEDGEFVYAVSEMNDSTAALSSLAFDRETGE
                     LRLLNTVPTFGADPCYVATNGREVLTANYSGGTMSVFPLQKDGTLAPADTLFQGSATGP
                     DAIRQATPHIHCTVFSPDGKYIFATDFSADRILRFVMHPDDPIPHASLEAVDIEADSGP
                     RHLTFSPNGKFAYLITELSGKVIAFSYDDGCLEQIQTITADTVAARGSADIHLSPDGKY
                     LYASNRLKEDGIAIFAVNPENGTLAKVGYQPTGIHPRNFNITPNGKYLLAACRDSNVIQ
                     VYKRNEVTGLLEDTHQDIVVDMPVCVQFVSSVNNL"
     CDS             complement(4777..7749)
                     /locus_tag="ctg48_7"
                     /transl_table=11
                     /translation="MEDIFSKRKTLRTIKADTSDYFIPLFHTLAVFLSTKETIITKRFL
                     EHIMKNLIALTLLLGGSTLLCAQKPAKTPATYKPVKSEMYRKGWIDFNKNGVKDVYEDP
                     SAPLEARIENLLQQMTLDEKTCQMVTLYGYKRVLKDDLPTPEWKELLWKDGIGAIDEHL
                     NGFQQWGLPPSDNAYVWPASRHAWALNEVQRFFVEDTRLGIPVDFTNEGIRGVESYRAT
                     NFPTQLGLGHTWNRELIRQVGLITGREARMLGYTNVYAPILDVGRDQRWGRYEEVYGES
                     PYLVAELGIEMVRGLQHNHQVAATGKHFAAYSNNKGAREGMARVDPQMSPREVENIHIY
                     PFKRVIREAGMLGVMSSYNDYDGIPVQGSYYWLTTRLRGEMGFRGYVVSDSDAVEYLYT
                     KHGTAKDMKEAVRQSVEAGLNVRCTFRSPDSFVLPLRELVKEGGLSEEVINDRVRDILR
                     VKFLIGLFDAPYQTDLADADREVEKEENEAIALQASRESIVLLKNAGELLPLDINSTKK
                     IAVCGPNANEEGYALTHYGPLAVEVTTVLEGIQEKTKGKAEVLYTKGCDLVDAHWPESE
                     IIDYPLTDDEQAEIDKAVENARQADVAVVVLGGGQRTCGENKSRTSLDLPGRQLQLLQA
                     IQATGKPVVLILINGRPLSINWADKFVPAILEAWYPGSKGGTALADILFGDYNPGGKLT
                     VTFPKTVGQIPFNFPCKPSSQIDGGKNPGPTGNMSRINGALYPFGYGLSYTTFEYSDLD
                     ITPRVITPNESATVRLKVTNTGKRAGDEVVQLYIRDVLSSITTYEKNLAGFQRIHLEPG
                     EAQELSFTIDRKHLELLDADMKWVVEPGDFVLMAGASSEDIRLNGTLTVEDYQTRAKAI
                     EAQKPAKRVSASTNPEDAENVLDEKINTAWQGNKGDYITFALKNGAKVDKVAIAFTRDN
                     NLPATFEIQLSGGGGQFLTVYSGTVSEYGKLISYPFKGTTASDLRIVLNDDRVSIAEVK
                     F"
     CDS             complement(8776..8913)
                     /locus_tag="ctg48_8"
                     /transl_table=11
                     /translation="MNIKGRGSRRKEKAPELLEFKDLQTSFYYIRGAGGNRTLVQTRKS
                     "
     CDS             9030..9515
                     /locus_tag="ctg48_9"
                     /transl_table=11
                     /translation="MKIHEGKCTEKILKERERIGSRLAILRKKRNMTQEELANLCGVNR
                     VNIAKIEKGAYNVSIDILSKVTSALGFVIDIKVDSSVCPTHFSQRKPVKLVIGKDYYVS
                     FGNNEAHRCKLVDIPEMYQGQRIKIETPTPRGSITHILFADEIGTTPDEAVMNQVTM"
     CDS             complement(9715..10512)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 55.3; E-value:
                     1.1e-16)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg48_10"
                     /transl_table=11
                     /translation="MQKRHTDRESYFDEQSQTSKNYYIPYIKEVIGHIPDKVLEVGCGE
                     GGNLLPFAKAGCRVMGVDIDAMRIEQARTFFTQRHQQGQFIATDIFQLKDKATNFPLIL
                     LHDVIEHIRDKERFLSGLQKHLSADGAVFVGFPAWQMPFGGHQQIAHSHIVSHFPFLHL
                     LPRTLYRWILRLCGEQERVITELLDIKSTGCTIELFNRIVRQANYQIIDRRLYLINPHY
                     KIKFGLSPRRLNGVIAAIPYIRNFFCTSCFYILKKGTKTVNHY"
     CDS             complement(10594..12024)
                     /locus_tag="ctg48_11"
                     /transl_table=11
                     /translation="MKKIMRNLALQYLNHANANPTIPLTDIPEEEEPAENPFCPDFISY
                     DKMLDIVESLPEGYCKVFKLAVLEGLSHKEIGDLLGIAPHSSSSQLFRAKILLKKMLAG
                     YRVFIVLTVLLLFPTLYDYLYREKKSIRENRLSKVSSRQAGSTQQTKKTDTPRTDEQCH
                     TKENLNKRERIIPPVPVSTEWPLAIPKMKDSIHKYPIPSPFTGQTITNRQMAFASSPSL
                     MPPTRKKKSRKWKLMLAGSLGPQLAQNLYKLIATPHTDGISSDFPQQVSTWEEYYSYLH
                     TRYQQGTLGKDSIGLMQIAQNNSGRIVENQQHHAPIVVGLSLSKKLNERWSLETGLQYT
                     LLRSEFTTGEAFRIQDNQKLHYIGIPLRLSYRFWHYKRFSSYATAGMQVDIPIKGTLQS
                     FHVTDSIPHKLDSQPVSAPWQWSVNTSIGIQYHLTPQAGIYLEPTVNYYIPDGSQLRTI
                     RKEHPFTFTLPVGLRISW"
ORIGIN
        1 cttgaaatta ttaaaaaatt aagtttgaat tatccaaaaa aaaatgctta ctttgcagac
       61 caaatcagat ttttggagaa attgattatt aacgctaaat caaaataaca aaatgtattt
      121 attattagtt atcttaatgc tgattgcatc tgtgctgatg tgcttcattg tattgattca
      181 aaattctaaa ggaggtggtc tggcatcagg cttttcatca tccaaccaaa ttatgggtgt
      241 gcgcaagact acggactttt tggaaaaagc aacctggact ctggcagctg tcatggtagt
      301 cttcagtatt gtttctgctt acactattcc ttcttccaca ggcaagggcg gtgatgtgat
      361 tctggaacag gcgcaacaag aagaaaaaac taatccttat aacatgcccg taggtacaga
      421 agctccgcaa tcggaggccc ctgcagctac aactccggct gaaactcctg ctcctgcagc
      481 agaagcccct gcagcagaat aagataagga tattgcggat gactcccgct tggaaaaata
      541 agagaaaggt tgatactgaa aaggtgtcag ccttttttcg ttttgatgaa gtatttattt
      601 acctttgtca gcaatttatg caatctgatt aataaattga aatccaaata gtacaatgac
      661 agaacaactc aaacttaaat tgaatgattc caaggctacc cgttgggggg cattggtgat
      721 tgttgccttc acgatgatgg tagcttatta tgtaaacgac gtggtagcac cgttgaagac
      781 aatgttggaa acggacttgg cttggtcgag taccgatttc ggattcttta ccggtggtta
      841 tagttttctg aatgtttttt tcctgatgtt gatttgggga ggattaatcc tcgaccgctt
      901 tggtatccgt ttcaccggaa agctggcaac tatcctgatg gtaggtggta cagcacttga
      961 atactatgca atgacgggac ttgccggtgc cgacgcgact ttattcggaa tcaatgaaat
     1021 atttggctat aaaacgggtg tgtttgttgc ttttgccggt tattccattt ttggagtagg
     1081 agcggaggtc gccggtatta cagtttccaa aatcatagcc aagtggttta aggggaaaga
     1141 gcttgccacg gctatggggg tacaagtcgc tttagcacgt atcggttcgc aagccggtta
     1201 tgccgtagcc attcctttgg cccgcgcttt cggtatttcc acaccggtgt tgttgggttt
     1261 ggttctgttg ttgggcggta tgattgcttt cttcatcttt gcagtgatgg acaagaagct
     1321 ggacaaacag atggaagctg ctgccattgc tgccggtacg gaagatgagg aagagaagtt
     1381 ctcttttaag gatgtgaaga atattctggt caatcccggt ttctggctga tagcattgct
     1441 gtgtgtattg ttctactctt gtgtattccc attccagaag tttgcttccg agttgatgat
     1501 tatcaaatac ggtatcaatg agaatgtggc cggtacattt gccggacttc cggcattggg
     1561 agcgctgatt ctgactccgg tctttggtgg tttcattgac aagcggggca agtccgcatc
     1621 tatcatgctg ctgggctcgg ccatgctgat atgtgtgcat ttcatttatg ctattcccga
     1681 tataaactat tggctggtag ctattgtgct gatgataatt ttgggtatcg ctttctcgct
     1741 ggtaccttct gccatgtggc cggctgtggc caagatattc ccggtaagcc agttgggtac
     1801 ggcatacgca ttgattttct ttatccagaa tatcggtctt tggggtattc ctacattgat
     1861 agggtgggtg cttgatgcct attgtatatc cggcaagaaa ccagatggaa cgaatatgta
     1921 tgactatacg gtgcctatgt gcatttttac cggtattgcc tgcttgtccc ttatagtggc
     1981 tctactgctg aagaaggcag acaagaagta tggttataag ctggaagagc ctaatattca
     2041 gaaataatag gaaaagcgga taccgtatga tggaaatacc cgaaggaaaa gtaagtctgt
     2101 tggacgctgt tccggtccgc tgtggacata taacaaccga atgggaaggt gagtgcgccg
     2161 tactcgccta cccacggttt aaatacgaat ggatgcgtcg ttttttattg ccgaagggga
     2221 tgtctcctga catccatgtg aggctggaag aacacggtac agctgtctgg aatctgatag
     2281 atggacatcg taccgtgcgc gaaatcatct ctctacttgc caggcacttt ggggaggaag
     2341 agaattatat tccccgggtc accgcctacg taatgcagtt gcgtaaggat ggatttatcc
     2401 agttgacaat ccggaattag aattccttta ttccctatct acttttatca atcctcccgt
     2461 tgccgtatca aacagcactt tgatggtaga attcttgttg aacagtaccg gtgcgaggta
     2521 ttctacggtg ccgaattggg taatgggaag ttggtcgtca aacaatttct tattgttata
     2581 catcaatgtc acttgtgcct tgcccggaag gttataggct acaccgtcca ctttcttttt
     2641 gccttcctcg gtggcagata catcgggact tttgaggtcg gtgacgctga tataatacgg
     2701 ttcaccggca aggtcattat tggccaccac tcccagcttc cgggaaaaac ggaaagccac
     2761 ctcatctttc atctctttag gcgtcagccg gatggtgaat gtcttgggtt ctttctttat
     2821 tttgcccgag aacatttccg tcatagccgt ttcctgctgg ttcagattgt caagcatcag
     2881 cttgagttgg gcgccgtcct tgggcatatt gtctgcttcg ccgcgcagga gggcattctt
     2941 gctttcgcgg atgctgtata tttccttggc caccagctcg gccatcttgg cactggagtt
     3001 ggacatcagt atttcttccg tcagaaaact gcgtgggtca atgctgcttt cggtggcttt
     3061 ggcttcgggc gtcttggcag caggcttacc gctgaacgga atgttgatgg agcggacaat
     3121 tccgtcttcg gtaagctcca taaggggtgc tacggtcttg tctttcatct tcacgaaata
     3181 gacgttgtcc ttatccggta caccggctat gcgggtttct atcttatcca gtgtccagaa
     3241 ctcctcgggt tcggcagaca cgttgttgag acgcagatag cggtcggcat atctgcaaaa
     3301 ttctccggga gtgtaggtat gcttggtggc ttgcaatacg atttctattt ctgttttggg
     3361 caacatataa gtcactccgt agtctttgcc acgcatcaca ccggtggtta cgtctgtttg
     3421 cgccatggca gtgatagaca agaacagagc tgagagcatc aatatattct tcttcataat
     3481 gtacattcgt ttagactgat ttagctaagg gacaaagtta atgaagttat ctttgctaaa
     3541 tattgcttta taaattatta acagagctga cgaactgtac gcaaaccggc atgtcgacta
     3601 caatgtcctg atgagtatct tccaagagtc cggtaacttc gtttcgtttg tatacctgaa
     3661 tgacattgct gtcgcggcag gcggcaagca agtatttgcc gttgggcgtg atgttgaagt
     3721 tgcggggatg gatgccggtg ggctgataac ctacctttgc caaggtccca ttttcgggat
     3781 tcacggcaaa gatggcgatg ccgtcttctt tcagacggtt gctggcgtag aggtatttcc
     3841 catccggact gaggtggatg tctgcacttc cacgggcggc tacggtgtcg gctgtgatag
     3901 tctgtatctg ttccaggcag ccgtcgtcgt aactgaaggc aatgacctta ccggacagtt
     3961 cggtgatgag ataggcaaac ttcccgttag ggctgaatgt cagatggcgc gggccggaat
     4021 ccgcttcaat gtcaacggct tccagagaag catgaggaat agggtcgtcg gggtgcatca
     4081 caaagcgcag gatgcggtcg gcactgaagt cggtggcaaa gatgtatttt ccgtccggtg
     4141 aaaagaccgt gcaatggatg tggggagtgg cttgccgtat ggcgtcggga ccggtggcag
     4201 agccttgaaa gagcgtgtct gcaggagcca aagtgccgtc tttctgtaaa ggaaagacgg
     4261 acatggttcc accgctgtag ttggcagtca acacttcccg gccattggtg gccacgtagc
     4321 aggggtcggc gccgaaggtg ggaacggtgt tcagcaggcg cagttctccc gtttcccggt
     4381 cgaaggcaag ggagctgagg gctgctgtgc tgtcgttcat ttcactgacg gcatagacaa
     4441 attcgccatc ttccgagggg acgaggtagg agggattggg caatgccgct gaactgagcg
     4501 gaacggctgt tcccgtctcc tgattaaagc ggaaggtata gatacccttg cttgagccat
     4561 tcgtgtaagt acctattagc atggcgagtt cgtcctggtc accgttagtg ccctttggag
     4621 aagagccaca tgctgtcaaa cctaatccga gcatacagaa aagaagtgtt ttcattaatt
     4681 taatgtgtta atgtgccaat atgctaatgt gctaattggc tgcgctgtat atgctgcatg
     4741 gtcattggta cattagcata ttggcacatt agcacattaa aatttaactt cggcaatact
     4801 gacgcggtca tcgttcagca cgatgcggag gtcgctggcg gtagtgcctt tgaacggata
     4861 ggaaatcagt ttgccgtatt cgctgacggt gcccgaatat acggtgagga actgtccgcc
     4921 accgcccgag agctggattt cgaaggttgc cggcaggttg ttgtcacgtg taaaggcaat
     4981 ggcaacttta tctaccttgg ctccgttctt taaggcaaag gtaatataat ctcccttatt
     5041 tccttgccat gcggtattga ttttttcgtc gagcacgttt tcggcatcct ctgggttggt
     5101 gctggcactc acacgctttg ctggtttttg ggcttcaatg gctttggcac gggtctggta
     5161 gtcttctacg gtcagcgttc cgttcaggcg gatgtcttcg gaagaggcgc cggccatgag
     5221 cacgaagtcg ccgggttcca ccacccattt catgtcagcg tccagaagct ccaggtgctt
     5281 gcggtcgatg gtgaaggaca gctcctgggc ttcgcccggt tcgaggtgga tgcgctggaa
     5341 gcctgcaaga ttcttttcgt aggtggtgat gctgctcagt acgtcgcgga tatagagctg
     5401 cactacttca tctccggcac gtttgccggt gttggtcacc ttcaggcgga cggtggcaga
     5461 ctcgttcggg gtgatgactc ggggggtgat gtcgaggtcg gagtactcga aggtggtgta
     5521 gctcaagccg taaccgaagg ggtagagtgc tccgttgatg cgtgacatgt tgcccgtagg
     5581 tcccggattc ttaccgccgt ctatctgtga agaaggtttg caggggaagt tgaaggggat
     5641 ttgccctacg gtcttgggga aggtcaccgt cagctttcca ccggggttgt agtcgccgaa
     5701 gaggatgtcg gccagggctg ttccgccttt ggagccggga taccaggctt cgaggatagc
     5761 ggggacgaac ttgtctgccc agttgatgga gagcgggcgt ccgttgatga gtatcagtac
     5821 gacgggcttg cccgtggctt gtatggcttg aagcagttgc aactgccgac cgggcaggtc
     5881 gaggctggtg cgcgatttgt tttcgccgca ggtgcgttgt ccgccgccca atactacgac
     5941 ggcaacatca gcttgacggg cattttctac ggctttgtct atctcggctt gttcgtcgtc
     6001 ggtcagcgga tagtctatga tttcactttc gggccagtgg gcgtccacca ggtcgcagcc
     6061 tttggtgtag agcacctctg ccttgccttt tgtcttttct tgaatgcctt ccagcacagt
     6121 ggtcacttct acggcaagtg ggccgtaatg ggtcagcgcg tagccttctt cattggcatt
     6181 gggaccacag acggcaatct tcttggtgga gttgatgtct aagggcaata gttcaccggc
     6241 attcttcagc agaacgatgg actcgcggga tgcctgcaag gcaatggctt cgttctcttc
     6301 tttttccact tcacggtcgg catcggcaag gtctgtctga tagggggcat cgaacagacc
     6361 gatgaggaac tttacccgaa ggatgtcgcg cacgcggtcg ttgatgactt cttcgctcag
     6421 tccgccttcc ttcaccagtt cgcggagggg aaggacgaag gagtcgggcg agcggaaggt
     6481 gcagcgtacg ttcagtccgg cttccacgct ttggcggacg gcttctttca tgtctttggc
     6541 ggtgccgtgc ttggtgtaga ggtattctac ggcgtcactg tcggatacga cgtagccacg
     6601 gaatcccatt tcgccacgca ggcgggtggt gagccagtag tagctgccct gcacggggat
     6661 gccgtcgtaa tcgttgtacg aactcattac gcccagcatg ccagcttccc ggatgacgcg
     6721 tttgaagggg tagatgtgta tgttttccac ttcgcgcggc gacatttgcg ggtccacgcg
     6781 tgccatgcct tcgcgggcgc ctttgttgtt actgtaagcg gcaaagtgct tgccggtggc
     6841 ggccacttgg tggttgtgct gcaagccgcg caccatttcg atgcccagtt cggctacgag
     6901 gtagggagat tcgccgtaaa cttcttcgta gcgtccccag cgctggtcgc gtcctacgtc
     6961 gaggatgggg gcgtagacgt tggtgtagcc cagcatgcgg gcttcgcgtc cggtgatgag
     7021 tcctacttgg cgaatcagtt cacggttcca ggtatgtccc agtcccagtt gggtggggaa
     7081 gttggtggcg cggtagcttt ccacgccgcg tatgccttcg ttggtaaagt ctacggggat
     7141 accgagacgg gtatcttcca caaagaaccg ttgcacctcg ttcagtgccc aggcgtggcg
     7201 cgaggcgggc cagacgtagg cattgtccga gggaggcagc ccccattgct ggaagccgtt
     7261 taggtgttcg tcgatggcgc cgataccgtc tttccagagc agctctttcc attcgggggt
     7321 ggggaggtcg tctttcagta cacgtttgta accgtagagg gtgaccattt ggcaggtctt
     7381 ttcgtccagc gtcatctgtt gcagcaggtt ttcgatgcgt gcttcgagcg gggcggaggg
     7441 gtcttcgtac acgtctttca ctccgttttt gttgaagtct atccaacctt tgcggtacat
     7501 ttcacttttc accggcttgt aggttgccgg tgttttggca ggcttttgtg cgcagagcag
     7561 tgtgcttcct ccaagcagca gggttagggc aataaggttc ttcatgatat gttctaaaaa
     7621 tctcttggtt attattgttt cttttgttga caaaaatacg gctaatgtgt gaaataaagg
     7681 gataaaatag tccgaagtat cggcttttat tgtccgaagg gtcttcctct tactaaaaat
     7741 atcctccaag acgctaccgg ggaattcaaa tcattattag acgaaacata tcattcactt
     7801 ttaaaaagaa agagagaaca ctataataac ctgaaaagta gatgcaatcg cggtgtatac
     7861 aagtattacg gctacatctg ttaaacgagg gtgtatttat ataataggaa tctgttggcg
     7921 gaattgttgc ttgtacggaa gaactttctt ttcaaccttg ggatgtctaa accaaacctt
     7981 ggtttagaca tcccaaggct gggtatgaaa aaaccaaagt ttgggataga ttgcttcctt
     8041 aattctttcc ggtttttcag ttaacttcag agactttttc cgttaatttc ccatctcttt
     8101 tgtgcaaata tccattacag aagatagata ttccctcttg cagggggtaa ttccgtcaac
     8161 ggatactggc tttggtagct gtttgaacat tgatgacaat ggggtgcaca tattctatgt
     8221 atggaagatt attgttttta tcacgaaaag tcagtattag ctaatatttg taaatatatg
     8281 gtgattgcta ataaaagaat atgtatcttt gggccaaaga aagcggtaga ggatgaaaaa
     8341 taaagtagca tttatccctt tttcaccctc cctacttagc aatgagttac gcaatctttt
     8401 aaatttcaga ccgttacaaa gtcatggggt tgactggatt tgacagcggg cagaaatggt
     8461 aagtaagcat gcagtgcgtc gttgatttgc actttaatct cagtcctcaa aattttatct
     8521 ggcgaaactc gttacgctct cgctgcttaa tcgaagtata gtagattgaa gcttaatccc
     8581 ggcaccaggt gctgggacgt gacatcactc ggaagctgtt gctccgaagc attccgataa
     8641 agtggtgcag tcaaatcggg gatagttcgt gtcagcctcg tggcgcgggt gaaaatttag
     8701 aggataaggc aacggttgat ggctttggtt ctgccgctgc acgaaaattt aggcaaagat
     8761 aagcatgtag aaagcttatg atttcctcgt ttggacgagg gttcgattcc ctccagctcc
     8821 acggatatag taaaaagaag tttgtaagtc cttgaattcc agtaattcag gggctttttc
     8881 ttttcttcta ctccccctac cttttatatt catttagaaa atagttgtag taaatgtgct
     8941 acaattcaaa attaatatct acttttgtct gttcaaaaat caataactat tagaagtggg
     9001 ggcaacactt taaattctgc aacagattta tgaaaattca cgaaggaaaa tgtacagaga
     9061 agattttgaa agaacgtgaa cggattggta gtcggttagc cattcttcgc aagaagagaa
     9121 atatgaccca agaggaattg gctaatcttt gtggtgttaa tcgtgttaat atagccaaga
     9181 tagagaaagg ggcttataat gtgagcattg atatactatc taaggtaaca tccgctcttg
     9241 gttttgtgat agatataaaa gtggatagct ctgtttgtcc gactcatttc tctcaacgta
     9301 aacctgtaaa gctggtaata gggaaagact attatgtcag ttttggcaat aacgaagccc
     9361 atagatgtaa gctggttgat attccggaga tgtaccaagg tcaaagaatt aaaatcgaaa
     9421 ctccgacccc gagagggtct atcacccaca tattatttgc cgatgaaata ggaacgacac
     9481 ctgacgaggc tgtaatgaac caagtaacga tgtaaaaaca ttaaaaggga ggaagtgcaa
     9541 gttcctcttt tattgaaatc accttcgcta caaccatctg cagcgagggg gattttttag
     9601 tttatgaggg tttctacacc cactctttca tcagagctat tcaaaaaatt aatggtttct
     9661 tctgaatata taatcttaaa ttgatggttc ggaatcaatt ctaaagctgg gaaatcagta
     9721 gtgattaaca gttttagtcc ctttctttaa tatgtaaaag caacttgtac aaaagaagtt
     9781 tcttatatac gggatagcag caataactcc gttgagcctt cgtggggaca agccgaattt
     9841 gattttataa tgtgggttta taaggtacag tctccggtca atgatttgat agttggcttg
     9901 ccggacgatg cgattgaaca gttcgatggt gcatccggtg ctctttatat ccagtagctc
     9961 cgtgattacg cgttcctgct caccgcatag tcttaatatc catctgtata aagtgcgggg
    10021 aaggaggtgg agaaaaggga aatgtgaaac aatgtggctg tgtgctatct gctggtggcc
    10081 tccgaatggc atttgccagg cgggaaaccc tacaaataca gctccgtcgg cagacaaatg
    10141 tttttgtagg ccggagagga accgttcttt gtctctgata tgctctatca catcgtgtag
    10201 aagaatcagg ggaaaattcg tagccttgtc cttaagctgg aaaatgtcgg tggcaatgaa
    10261 ctgtccctgc tgatgccttt gggtgaagaa ggtcctggct tgctctattc gcatggcatc
    10321 aatgtctacg cccatcaccc ggcaaccggc tttggcaaag ggaagcagat tgcctccctc
    10381 tccacagccc acttccagca ctttatcggg gatgtgtccg atgacttcct ttatgtaggg
    10441 gatataatag ttcttgctgg tctgtgactg ttcatcaaag tagctttccc ggtcggtatg
    10501 tcgtttctgc atgttctttg ttccttcttg agtttgatta tccatataaa tagataatca
    10561 gtcgggtaaa agactgcgtg gcgcatcgtt tttttaccag gaaatgcgga ggcctaccgg
    10621 gagggtgaat gtgaacgggt gttcctttcg gatggtgcgc agttggctgc cgtcggggat
    10681 ataatagttt acagtcggct ccagatagat gcctgcctgg ggtgtgaggt gatattgtat
    10741 gcctatactt gtgttgaccg accactgcca gggagcactt accggctggc tgtcgagctt
    10801 gtgtggaata ctgtctgtga catggaagct ttggagtgtc ccttttatgg ggatatccac
    10861 ctgcatgcct gccgtggcat aactggagaa acgtttgtaa tgccagaaac ggtaggaaag
    10921 ccggagagga atgccgatat aatgcaactt ctggttgtct tgaatgcgga atgcttcgcc
    10981 ggtagtgaac tccgacctga gaagcgtata ttgcaatccg gtttccagac tccaacgctc
    11041 attcaatttc ttgctgagag agagtcccac gacgatgggg gcatgatgtt gctggttctc
    11101 aacaatcctg ccgctgttat tctgggcaat ctgcatgagt ccgatggaat cttttcccag
    11161 agtaccctgc tgatagcggg tgtgcagata agaataatac tcttcccacg tgctgacttg
    11221 ttgagggaag tcacttgaaa tgccgtcggt atgtggagtg gcaatcagct tatataagtt
    11281 ctgtgccagt tgcggtccga gtgaacctgc cagcatcaac ttccatttcc tggatttctt
    11341 cttgcgggtt ggcggcatta gggaagggga ggaggcgaaa gccatctgcc ggttggtgat
    11401 ggtctgtccg gtgaatggag aaggtatggg atatttgtgg atgctatctt tcattttggg
    11461 tatggcaagg ggccattctg tggaaacagg aacgggaggg atgattcgtt cccttttgtt
    11521 cagattttct ttggtatggc attgttcgtc ggttcgggga gtatcggttt tctttgtttg
    11581 ttgcgtactc ccggcttgcc tggaagaaac tttggacaaa cggttttccc tgatactctt
    11641 tttctctctg tacagatagt catatagcgt tggaaagaga agcaatactg tcaaaacaat
    11701 gaatacacgg tatcctgcca gcatcttttt aagtaaaatt ttcgcccgga acaattggga
    11761 ggaagaggag tgtggcgcta tacccagtaa atctccgatt tctttgtggg acaatccttc
    11821 cagtactgcc agtttaaata ccttgcagta gccctccgga aggctctcca ctatatccag
    11881 catcttatcg tacgaaatga aatccggaca aaaaggattt tcagcaggct cttcctcttc
    11941 cggaatatct gtcaatggga tggtggggtt ggcattggca tggttgaggt attgcagtgc
    12001 caggtttctc ataatctttt tcatccagta ttccagtttc tccgggttgc gcagcgaatg
    12061 aatggaagtg aatatgatga caaaaccgtc gtgaagaaga tcttgggcta tcgttgggtc
    12121 gggaatatag cgtaggcata ctttcagcat tttctctgaa tagttttcgt agagcaggct
    12181 caaggcctgc ccgtttccct tctggcataa agtgacaaga gcttttgtat ccatgtgttt
    12241 gtctcaatgt tatttcttaa ggatagagaa gaacatgaat gactgcatgg atttttattt
    12301 tttaactaag cctcccggtt gacttctgct gcacagtccg gacaaatgcc tttcagtaca
    12361 tagttgatgc tgttcagcgt aaatccttga ggcagcttca ccaccggagt gggaatgttg
//
