LOCUS       c00066_gnlPro..        13730 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LAOPKKDA_66.
ACCESSION   c00066_gnlPro..
VERSION     c00066_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 06:41:47
            Original ID  :: gnl|Prokka|LAOPKKDA_66
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13730
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13730
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[244:3730]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      245..3730
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13730
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13730
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(245..1000)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_1"
                     /sec_met_domain="Fer2_3 (E-value: 1.2e-26, bitscore: 83.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 3.8e-12, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4e-06, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDIKVTLKVWRQKSPKDKGQFETYQIDKINQSVSFLEMLDILN
                     ERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANSIAIPRADAEMAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFICAKLQD"
     CDS             complement(1028..2971)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 195.7; E-value:
                     4.7e-60)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_2"
                     /sec_met_domain="FAD_binding_2 (E-value: 1.3e-60, bitscore:
                     195.7, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.3e-38,
                     bitscore: 122.1, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQIDSKIPQGPLAEKWKNYKDHQKLVNPANKRRLDVIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRMIGLNKVKMYTRHEMLDVVKVDGRARGIIARNLITGQIERFSAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDYQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSDAINRLGKDVVKAKYGNLFDMYEEITNDDPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFAEAEKGIKDRIKKLMSIKGKESVDSIHKKLGHI
                     MWEHVGMARDAKGLQEAIQMLKELKKEFWSNVYIPGEADNLNVELDKALRLADFIEIGT
                     LMAHDALDRAESCGGHFRTEHQTEEGEALRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     QFVVPQTRNYKK"
     CDS             complement(3005..3730)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_3"
                     /sec_met_domain="SucD_FumR (E-value: 3e-76, bitscore:
                     245.5, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSVSGLFLVLFLLFHLSMNVAAAFSGEAYNMI
                     CSLLGANWYAVAATLVLAAGVVIHFVYAVLLTLQNRKARGNDRYAINARPKGVEWASQN
                     MLVLGIIIILFMVLHFSQFWYKMMFAELLGNHMVTLCDGTTTVSPQDGAAFINYYFQGN
                     ILNTVLYLVWYVALWFHLTHGFWSAIQTIGWSNTIWMNRWICISKIVATVICVVFAIIT
                     IVFYLNGVGGDYVAVCAGH"
     CDS             4119..5366
                     /locus_tag="ctg66_4"
                     /transl_table=11
                     /translation="MLRVPVPLFAISAITYGQGDKFRTLRNTHTPNFHYRYDDFLQYTP
                     LLAVYGMKLGGVESRSSWPRMIVSNAFSATIMAATVNSMKYTIKRERPDGSKNNSFPSG
                     HTATAFMAATIMHREYGLTRSPLYSIGGYTVATATAFSRQLNNRHWLSDVLAGAGIGIL
                     STELGYFLADLIFKDKGLNLPDKLRESAPKGGRPSFLEFAVGYSIINGSIEVGKNIRLS
                     SPGATNVSVKGGYFFNPYFGIGGEITALASPMAFDMSLYTGTTPSTKYDITRVHADPTG
                     VFTFTAGPYFSLPVASKLLLGTKFQAGYSYLVKNEVEMDLQEKPPSYGTINNIVFMKGN
                     GSSNYVLRTGISATGIVSRNLGIRMFVDYDYTFLKAPYEILTSLRDSQPVYGESHLSKH
                     KIHYFTIGATVTALFW"
     CDS             complement(5370..7193)
                     /locus_tag="ctg66_5"
                     /transl_table=11
                     /translation="MNKTILLVVFCFSLFVSGYSQGIRFDSYPSHPRLLVKKGEEQKIK
                     SDLALNPEMLRLHNYLLKQCDDLITTPVLAYKKEGKRLLAVSREALRRIFYLSYAYRMT
                     GEDKYRLRAEQEMIAVCSFADWNPSHFLDTGEMTMAVAIGYDWLFDRLSPDARRLVQEA
                     ILNKGFAPSRDKRYNWFLRATNNWNQVCNAGLVYGALAVLEDHPEEAREIIERALSTVG
                     LTLKGYGPDGAYPEGYNYWGYGTTFQVLLNAALESALGTDGGLSSAEGFLASARFMQFM
                     TGTTGKCFNFSDSRESVFALPAMYWFADKLQDPTLLWNEKDMLSRAELSFSDEESRFLP
                     LIPIYGSQYKMNELVPPAMKLWAANGQTPVVLVRTGWENGEGFYLGIKGGTASTSHAHM
                     DAGSFVFDALGVRWVQDLGMQEYYSLEKENVDLWNMSQNGQRWNVFRYNNLAHNTLTVN
                     GKYHDVNGFVPVTNIYSEAHKLGASLNMTDLFGGELENAVREVALINEKYLSVIDRVKA
                     GSQPATVRWTIVTGAIPRVLDSHMVELTKDGKCMQLIVDSPSVTSVSVLDNVSKNSYDA
                     SNEGTCRIVFDVSLESGQESDIKVRLVPAAD"
     CDS             7924..8400
                     /locus_tag="ctg66_6"
                     /transl_table=11
                     /translation="MKTLVHTEKEHIEEIIRSCDVCFVGLADTDGTPYVIPMNFGYRNG
                     VIYLHSAQEGRSISILERNPKVCITFSTDHDLVFQHPEVACSYRMRSKSVIAWGKVRFE
                     EDFDKKTEALDIIMKQYSDKEFRYSDPAVKNVKIWLVDLDEVTCKEFGAPHKKY"
     CDS             8421..8891
                     /locus_tag="ctg66_7"
                     /transl_table=11
                     /translation="MKNLLAIFLMVFLFASCEGPMGPPGRDGEDGGITYWIFDKDIQVK
                     SSDWELVDNGNNEPFYMYEYRIADKDFDIYQDAYKEGLITCYMYLDHGEDKEAQTALPN
                     PVNRIDKENNIWTETYAAEYTKDGFIIFKVTFSDFFTDQRPPETHFKAVITY"
     CDS             8950..9849
                     /locus_tag="ctg66_8"
                     /transl_table=11
                     /translation="MGLQKHSKVLNETVEKLSDECSYKQLFHAYRDEEALPSGEVLEEI
                     IDLCRAILFPGYYGNARISTQTIRFHTGVNIEKLHELLSRQIYAGLCLADTSCTSCAEE
                     LIFSQAEKLSEAFISTLPEMRCLLATDAEAAYNGDPAAQNINEVIFCYPGFRAIGNYRI
                     AHQLYKLGVPFIPRMITEMAHSETGIDIHPGAQIGHYFSIDHGTGTVIGETSVIGNNVR
                     IFQGVSLAGEKLPPDENGNAIRGVPRHPILEDNVTVYSNATLLGKIRVGKGATICGNVW
                     ITGDVPPGAVITQNKVTK"
     CDS             9875..11473
                     /locus_tag="ctg66_9"
                     /transl_table=11
                     /translation="MNNETFEMVAKTLYGLEEILAGELLAIGANDIEIGRRMVSFTGDK
                     EVLYRANFCCRTALRILKPIYHFKAKDADTVYKEVKKVVWENYMSLDKTFAIDSVIYSE
                     DFNHSKFVAYRTKDAIVDYFMEKHNKRPSVRVNNPDLYINIHISHNDCTLSIDSSGESL
                     HKRGYRVEQTEAPLNEVLAAGMILKTGWKGESNFVDPMCGSGTLLIEAAMIALNIAPGI
                     HRKEFAFEKWIDFDQELFDRIYNDESQEREFTFKCYGSDINPAAIEIAQKNIRSAGLAK
                     YVELKTMPFQQYTEAPQPGILVTNPPYGERISSRDLLGLYNMIGERVKHVFTGYKVWIL
                     SYKDECFDKIGLRPSERMKLINGSLDCEYRCYEIFEGKNKDYKKALNEEGAERTEDSAS
                     RPRPSFPEKRYDTRPAGRPNFKTDRMDRPDRRFAAAHSEDENERTSAAPGKRFFGEERG
                     DGRPARKQFGGERGERPVRPILHKAGEKRPVKMRYKDEDDRFSKNRKNFGDRKRGEGRP
                     FKKPFRREDNDDFED"
     CDS             11660..13651
                     /locus_tag="ctg66_10"
                     /transl_table=11
                     /translation="MXXXXXXXXXXXXXXXXXLPTVGSLPGFSVPYKDQPVLAFTSKGH
                     RLHYNFAENKIIGNYQLDSKGSNYNFCPANNCLAFTVGNNIQILSPENQTSIVTRETKD
                     GIVCGQAVHQREFGISKGLFWSPAGSALAFYRMDESMVTDYPIVNIDARQAKAEPVKYP
                     MAGMKSHEVTVGVYNLSTGETVWLETGTPKEKFLTNIAWSPDEKSIYIAELNREQNEMN
                     LVRYSALTGKKEAVLFTETNEHYVEPQYSVLFLPNDPGKFIWQSQKDGYNHLYLYDTTG
                     KQLKQLTQGEWVVTQVIGFDAKGENLFITSTQPHIRSSFNYGTPMNVNGWKLNLKKGET
                     SLLTPNAALESVHNLSVSASGKYAIDSYDAPKIPRIINLIRTKDGKEIKNLLTARDPYK
                     GYTLPEIEAGTIKSADGTTDLHFRLVKPVGLDENKKYPTIVYVYGGPHSQLVTGGWQNG
                     VRGWDIYMAQRGYVVFTVDNRGTSNRGFAFESVIHRNLGVNEMADQMKGVEYLKSLPYV
                     DADRIGVHGWSYGGFMTTNLILTHPDVFKVGVAGGPVIDWSNYEIMYGERYMDRPQDNP
                     EGYKNANLKLKAGNLKGHLLQIHGDIDPVVVWQHSLGFLKACVDADTYPDYFVYPRHEH
                     NVTGKDRPHLYEKITRYFDDYLKNTNKE"
ORIGIN
        1 acaagcccta accaactttg ttaaccttaa atctaatact attatgaaaa aaccatagta
       61 caaagataca ggtattctcc aacttgtcaa tagttaaaat gctaattagt gttgtatagc
      121 atataagaaa cactaacaac attcaagata tttatctatg acttcagaaa tgttaaaata
      181 ggggcaaaaa agaagaggcg ccgccataag caacgcctct ccggacatac atatataatg
      241 tatattagtc ttgcaattta gcacaaatga actcgcggtt caaacgagcg atgttgctga
      301 cagagatgtt cttcggacat tccatttcgc aagcacgcgt gttggtacag ttaccgaagc
      361 ccagttcgtc catcttggca accattgctt tcgcacgacg agcagcttct accttaccct
      421 gaggcaacag agccaactgg ctaacctttg cagaaacgaa caacatagcc gaaccgttct
      481 tacaagcagc agcacaagca ccgcaaccga tacatgcagc agcatccata gccatttcag
      541 catctgcacg aggaatagcg attgaattgg catcaggtac accacctgtg ttcactgata
      601 cgaaaccacc tgcctggata attttatcgt aagcataacg gtctaccatc aagtcgcgga
      661 ttaccgggaa accggcagaa cgccacggtt cgattgtaat agtttcgcca tcattgaagc
      721 gacgcatata aagctggcaa gtagttgcgc cggttgcagg tccgtgcgga tgtccgttta
      781 catacaaaga acacataccg cagatacctt cacgacagtc gtgatcgaat acgatcggct
      841 ctttaccttc actgaccaaa cgttcattca aaatgtctaa catttccagg aaagaaacac
      901 tctgattgat tttgtctatt tggtaagtct caaattgtcc tttatctttc ggacttttct
      961 gacgccaaac tttaagtgtt acttttatat ctttatccat gattctaatt tttgtgattg
     1021 atgattatta cttcttgtag ttacgtgttt gaggaacaac gaactgatag ttcaaatctt
     1081 ccttcagcat aaccggatct ttgtcttcac cctggtattc ccaacaagat acgtacatga
     1141 acttatcgtc atgacgcagg gcttcgcctt cctcggtctg gtgctctgta cggaagtgtc
     1201 ctccacaaga ttcggcacgg tccaatgcat cgtgtgccat caatgtacca atctcaataa
     1261 agtcagccaa acgcaatgcc ttatccaact ctacgttcag gttatcggct tcacccggaa
     1321 tatatacatt actccagaac tctttcttca gctctttcaa catctggatc gcttcctgca
     1381 aaccttttgc atcacgtgcc atacctacat gttcccacat gatatgaccc agtttcttat
     1441 ggatagaatc taccgactct ttacccttga tactcatcaa tttcttgatg cggtctttga
     1501 tccccttttc agcttctgca aactcaggca ggtcggtact gaaacgcgga acctggatct
     1561 ggtctgacag atagttctgg attgtataag gcaatacaaa gtagccatcg gccaatccct
     1621 gcatcaacgc agaagcaccc agacggttag ctccgtggtc agagaagtta gcttcaccga
     1681 tagcgaacag acccggaata gaagtcatca attcatagtc aacccacaga ccacccatcg
     1741 agtagtgcaa tgcaggataa atcatcatcg gagtttcgta tggatcgtcg ttggtaattt
     1801 cttcgtacat gtcgaacaag ttaccatatt tagcttttac aacatcttta cccagacggt
     1861 tgatggcgtc ggagaagtcg aggaacacgg ccagacctgt gttgttcaca ccgaagccgg
     1921 cgtcgcaacg ttctttagcg gcacgtgaag ccacgtcacg cggaaccagg ttaccgaatg
     1981 ccggataacg gcgttccaga tagtagtcgc ggtctgcttc aggaatgtct ttccctttct
     2041 tagttccggc ctgtaatgct tttgcatctt ccagtttctt cggaacccag atacgaccgt
     2101 cgttacgcaa tgattcagac atcaaagtca gcttagactg gtagtcacct ttcaccggta
     2161 cacaagtcgg gtggatctgc accatacaag ggttagcgaa gtaagcacct ttcttgtagc
     2221 actgccatgc agcagaaccg ttggaagcca ttgcgttagt agacaggaag aaagtattta
     2281 cataaccacc tgttgccacc actactgcgt gagcagagaa acgttcgatc tgacctgtga
     2341 tcaggttacg tgcgatgata ccgcgggcac ggccatccac cttcacaacg tccagcattt
     2401 cgtggcgggt atacatcttt actttgttca aaccgatcat acggctcaaa gcagagtaag
     2461 cacccagcaa caactgctgt ccggtctgac cgcgggcata gaacgtacgg gatacctgag
     2521 caccaccgaa tgaacggtta tccagcagac caccgtattc gcgagcgaaa ggaacaccct
     2581 gtgctacgca ctggtcgata atagagttgg aaacttcagc cagccgataa acgtttgctt
     2641 cgcgggcacg atagtcacca cctttgattg tatcgtagaa cagacggtaa acagagtcac
     2701 catcattctg ataattcttt gcagcattga taccaccctg tgcggcgatt gagtgtgcgc
     2761 gacggggaga atcctggata cagaagttca atacgttgaa tcccatttct gccagagagg
     2821 cagcagcaga agcaccggcc agaccagtac caactacaat cacgtccaga cgacgtttgt
     2881 tcgcggggtt caccagtttc tgatgatctt tataattttt ccacttctca gccaacgggc
     2941 cctgagggat tttagaatct atttgagtca taatgattta ttttcaatat tgttacacct
     3001 taaattaatg tcctgcacaa acagctacat agtcaccacc tacaccattc aggtagaaaa
     3061 cgatagtaat gatagcaaac actacgcaaa taacggttgc tacaatcttg gaaatgcaga
     3121 tccaacggtt catccagatc gtgttactcc aaccgatagt ctgaatagcg ctccagaacc
     3181 cgtgagtcag gtggaaccac aaagctacgt accataccag atacagcact gtattcagga
     3241 tattaccctg gaaatagtag ttgataaacg ctgcaccgtc ctgaggagat acggttgttg
     3301 ttccgtcgca aagtgttacc atgtgattgc ctaggagttc ggcgaacatc atcttatacc
     3361 agaactggct gaagtgcaac accatgaaca ggataatgat aatacccagt accagcatgt
     3421 tctgagatgc ccattccaca cctttcggac gagcgttaat tgcataacgg tcgttaccgc
     3481 gagccttacg gttttgcagt gtaaggagaa cagcatacac aaagtgaatc acaacgcctg
     3541 ctgccagcac caatgttgct gccacggcat accaatttgc tcccaacaat gaacaaatca
     3601 tgttataggc ttctcccgag aaagcagccg ccacattcat tgacaagtgg aacaataaga
     3661 acaaaacaag aaaaaggcct gatacactca ttatcagctt cttcccgata gaagaattaa
     3721 gtaaccacat aagataataa tttaagttat ttaattgttt ttagaaattc atatcaatat
     3781 actcaattat caggcaaagg tatgctaaat acacgtatca cgcaaacgat taaagaaata
     3841 tttcgtcaat caaacctata catttcagga gggacaaacg gtaaatccta ttcaataaat
     3901 aaattaacaa aaatgtaacc agtactaacc ggcattttta tatcttcgtg gcataatcag
     3961 gggatcgtat gttacaacgt aaaatgctga gcttcttatt tatgatgatt tttataccgt
     4021 ctgttcgtgc tcagtgaaaa gatagtacga gattcataaa taaagaacat gaatttgaaa
     4081 ccacttacaa caaaatatca gagaataagg tataccagat gctacgtgtc cctgttcctc
     4141 ttttcgccat ttcagccata acatatgggc agggtgataa attccggaca ttgcgcaata
     4201 cgcatacgcc caacttccat tacagatacg atgattttct gcaatatact ccgttgcttg
     4261 ctgtttacgg gatgaagctc ggcggtgtgg aaagtcgtag ttcatggccc cggatgatcg
     4321 tatcgaacgc tttttcggca acgatcatgg ccgctaccgt caacagcatg aaatatacga
     4381 tcaaacgcga acgccccgac ggctcaaaga acaactcatt cccttcggga cacacggcaa
     4441 ccgctttcat ggctgctacc atcatgcacc gggaatatgg tctgacccgc agcccgttat
     4501 atagtatcgg gggatataca gtcgccacag ccaccgcttt cagccggcaa ctgaacaacc
     4561 gccactggct gagcgacgta ctggccgggg ccggtatcgg catcttatcc acagagttag
     4621 ggtattttct ggcagacctg atcttcaagg acaaaggctt gaatctccct gacaagctca
     4681 gggagtctgc ccccaaagga gggcgccctt ctttcctgga gttcgccgta ggatacagta
     4741 tcatcaacgg aagtatcgag gtaggtaaaa atatacgcct gagctcgccg ggagcaacca
     4801 atgtcagcgt aaaaggcggt tacttcttca atccttattt cggtatcggc ggcgaaataa
     4861 cagcgctggc aagcccgatg gcattcgaca tgtcgcttta tacaggaaca accccttcaa
     4921 ccaaatatga catcacccgc gtccatgccg atccgaccgg tgtttttact tttacggcag
     4981 ggccttattt ttcgttacca gtagcaagca agctgctttt aggaacaaag ttccaggccg
     5041 gatattccta cctggtgaaa aatgaagtgg aaatggactt acaggaaaag cccccctcat
     5101 acggaaccat aaataatatt gtttttatga aaggcaacgg tagcagcaac tatgttttac
     5161 gcacaggcat ttcagcgacc gggatcgtca gccgcaacct gggtatccgt atgttcgtag
     5221 attacgatta tacgttcctg aaagcacctt acgaaatctt aaccagcctc agagacagcc
     5281 aaccagtcta cggcgagagc catttaagca agcacaaaat acactacttt acgattggcg
     5341 caaccgtaac ggcactgttc tggtaattat cagtcagcag caggaaccag ccggactttg
     5401 atatcgctct cctgcccgct ttccagactc acatcgaaaa cgatacggca ggttccctca
     5461 ttggaagcat catagctatt cttcgataca ttatcaagga cggacacaga agttacggac
     5521 ggactatcaa cgatcagttg catacatttg ccgtcttttg tcagttccac catatgactg
     5581 tccaatacac ggggaatggc cccggttaca atcgtccatc tgacagttgc cggctgactg
     5641 ccagctttta cacgatcaat caccgacaga tatttttcat tgatcagagc aacttcacgg
     5701 acggcatttt ccaattctcc gccgaacaag tccgtcatat tcagagaagc tccgagttta
     5761 tgcgcttccg aatagatatt tgtcacaggt acaaaaccgt ttacatcatg gtatttaccg
     5821 tttacagtca gtgtattatg cgccaggtta ttataacgga acacattcca gcgctgcccg
     5881 ttctgcgaca tattccataa atctacattt tccttttcca gcgaataata ttcctgcatc
     5941 cccaggtcct gcacccagcg aacacccaaa gcatcgaaca caaacgatcc ggcatccata
     6001 tgggcatggc tggtcgaagc cgttcctcct tttattccca gatagaaacc ttctccattc
     6061 tcccaacccg tacggaccag cacgacaggc gtctgtccgt tagccgccca caatttcatg
     6121 gcaggaggta ccagttcatt cattttatat tgtgaaccat aaatcggaat caacggaagg
     6181 aaacggctct cctcatccga aaaagacaac tccgcccgac tcaacatatc cttttcattc
     6241 caaagcagtg tagggtcttg cagcttgtcg gcaaaccagt acatagccgg caaagcaaag
     6301 acactctcac gggaatcgct gaagttaaag catttaccgg tcgttccggt cataaactgc
     6361 ataaaacggg cagaagccag aaaaccttca gccgaagaga gaccgccgtc agtccccagg
     6421 gcggattcca acgcggcatt caaaagaacc tggaaggtag tcccgtatcc ccaataatta
     6481 tatccttcgg gataagcgcc atcgggacca tagcctttca aagtcaggcc gactgtagat
     6541 aaagcacgtt caatgatttc acgggcctct tccggatgat cttctaaaac ggcaagtgca
     6601 ccgtaaacca gtccggcatt acagacctgg ttccagttat tggtcgctct cagaaaccag
     6661 ttatatcttt tatccctcga cggggcaaaa cctttattca gaatcgcctc ctgcaccagc
     6721 ctccgggcat ccggagataa ccgatcgaac aaccagtcat aaccgattgc aaccgccata
     6781 gtcatttcgc ccgtatccag aaaatgggac gggttccaat cggcaaacga acacacggca
     6841 atcatttcct gctctgcccg caaacgatac ttatcctctc ctgtcatccg gtaagcatat
     6901 gaaagataga agatacgccg caaggcttca cgcgatacgg ccagcaaccg tttcccttct
     6961 tttttatatg ccagcacagg cgtcgtgatc agatcgtcgc attgcttgag aagatagtta
     7021 tgcaaccgga gcatttccgg attaagagcc agatcggatt taatcttttg ctcctctcct
     7081 ttctttacca gcaaccgggg atgagaaggg taagaatcaa agcgtattcc ctgtgaatac
     7141 cccgaaacga acagggaaaa gcaaaacaca acaagcagga tagttttatt catacaggta
     7201 ttatatttaa ttggagttac aaatatagga aatcgcttga taaagtgttt tcttatccgg
     7261 aatcctttta acagacaata aaataccatt ttgctacaat ttacaacgat taaagatcat
     7321 tttgtatatt ttttccgcat atacgtatct gctatatttc acaaaacagt agaaatagaa
     7381 gatccgaaaa cacaatattt aacacttagc gtattcatat agattttcac tcttcatttt
     7441 aaacaaattg taatctcgtt taaaacgaat tttttttcat tttaaatgaa atggagattt
     7501 attgcagatg aaaaatttgt taattctgtc caaaaaagtt attttaaaca ggccttggga
     7561 cctcaaatca catgctaaac aacacatttt atctccagaa cgagtaaata tccaaaccaa
     7621 acccgaacag cacattcata tatttcaaat gtactttacg acatttatca acaactacca
     7681 cacatcatca aacataaagc cacatttatt aatcaacaat taaaataaag acattcgcaa
     7741 tcatcccgta gagcgaataa aaacaacaaa cctgatttag gacacgtaca gctcactgac
     7801 agaagggcta tttgacattt tgacacattg acgaaaacag tacatatata ataaagtcgc
     7861 aaaagtaagt ccgagaagtt gaactttttt actatgtttg caaaagcata attaaaaata
     7921 gtaatgaaga cactggtaca cacagagaaa gaacatatcg aggagattat ccgtagttgc
     7981 gatgtctgtt tcgtcggact ggctgatacg gatggtacgc cttacgttat tcccatgaac
     8041 tttggctatc ggaacggtgt tatctattta cattcagcgc aggaaggccg aagtatctca
     8101 atcctggaac gtaacccgaa ggtttgcatc accttcagca ccgaccatga tctggtattc
     8161 cagcatcccg aagtggcttg cagctaccgt atgcgttcca aaagcgttat cgcatggggt
     8221 aaagtgcggt ttgaagaaga cttcgacaag aaaacggaag cgctggatat aattatgaaa
     8281 cagtattcgg acaaggaatt ccgttattcc gacccggctg tgaaaaacgt aaaaatatgg
     8341 ctggtagacc tcgatgaagt aacatgcaaa gagttcgggg caccgcacaa gaaatactaa
     8401 acatttaaga gagtgaatat atgaaaaatc tgttagcaat atttttaatg gtgttcctgt
     8461 tcgcttcatg cgaaggaccg atgggccctc cgggacgaga cggggaagat ggcggtataa
     8521 cctactggat atttgacaag gatatacaag ttaagtcaag cgactgggaa ttagtcgaca
     8581 atggtaataa cgaacctttt tacatgtatg agtacagaat tgccgataaa gatttcgaca
     8641 tatatcagga tgcttataaa gaaggcttaa ttacctgtta catgtatctg gatcacggcg
     8701 aagacaaaga agcacaaact gcattaccca accctgtcaa tcgaatagat aaagagaata
     8761 atatctggac ggaaacctat gcagccgaat acaccaaaga cggtttcatc atcttcaaag
     8821 tgacattctc cgacttcttt actgatcaac ggccgccgga aacgcatttc aaagcagtta
     8881 taacctatta aaagtacaca tatatcagat atttaatgta cttttgccca aaataagact
     8941 ttcaaaataa tgggattgca aaagcatagc aaggtattga atgaaacagt agaaaagctt
     9001 tcggacgaat gttcatacaa acaactgttt catgcctacc gcgatgaaga ggcattgcct
     9061 tcaggtgaag tactggagga gatcattgac ttgtgccgtg caatcctgtt tcctggctat
     9121 tacgggaatg cgcggatcag tacacagacg atccgtttcc ataccggggt caatattgaa
     9181 aagttgcacg agctgctcag ccgtcaaatc tatgcgggcc tttgcctggc cgacaccagc
     9241 tgtacttcct gtgcggaaga gctgatcttc agccaggcag aaaaactttc cgaagcgttc
     9301 atttccacac tgccggaaat gcgctgtctg cttgccaccg atgccgaagc cgcctacaac
     9361 ggtgatccgg cagcacaaaa catcaatgaa gttatcttct gttacccggg cttccgggca
     9421 ataggcaatt atcgtatagc gcaccagctt tataagttgg gcgttccttt tataccccgg
     9481 atgatcaccg aaatggctca ttccgaaacc ggtatcgaca ttcatccggg agctcagata
     9541 ggacattatt tctctatcga ccacggcacg ggtaccgtga tcggcgaaac cagtgtgatc
     9601 gggaataacg tacgcatctt ccagggtgtc agccttgccg gagaaaagct gccgcccgat
     9661 gagaacggga acgcgatccg cggtgtcccc cgccatccca tcctggaaga caatgtgacc
     9721 gtctactcca acgcgacgct attggggaaa atacgggtcg gcaaaggtgc cacgatatgc
     9781 ggcaacgtct ggatcaccgg agatgttccc cccggtgctg tcattacaca aaataaagta
     9841 actaaataaa tatcttttct tacaacgcac gcaaatgaat aacgagacat ttgaaatggt
     9901 ggccaaaacc ctgtacgggt tagaagaaat actggccggt gagttattag ctataggcgc
     9961 caacgatata gaaattggcc gccggatggt atccttcaca ggagataaag aagtgcttta
    10021 cagagccaac ttctgttgcc gcaccgcctt acgcatcctg aaaccgatct atcatttcaa
    10081 ggcaaaagat gccgatacgg tttataagga agtgaaaaag gtcgtatggg aaaactatat
    10141 gtcactggac aagacgttcg cgatcgactc cgtgatctat tcagaagatt tcaatcactc
    10201 taaattcgtg gcttaccgta caaaagatgc gatcgttgac tactttatgg agaagcacaa
    10261 caaacgtcct tccgtacgtg taaacaatcc cgacttatac atcaatatac atatctcgca
    10321 caacgattgt accttgtcta tcgacagttc gggcgagagc cttcacaaac gcggataccg
    10381 tgtggaacag accgaagcgc cgctgaacga agtgctggct gccggtatga tcctgaagac
    10441 aggctggaaa ggcgaatcca atttcgtcga cccgatgtgc ggttccggta cgctgctgat
    10501 cgaagcggct atgatcgccc tgaacatcgc cccgggtatc caccgcaagg agttcgcttt
    10561 cgagaaatgg atcgacttcg accaggaact gttcgaccgc atctataacg acgaaagcca
    10621 ggaacgcgaa ttcactttca aatgctacgg ttcggatatc aacccggccg ctatcgagat
    10681 cgcccagaag aatatccgta gcgcaggcct ggccaaatac gtcgaactga aaacgatgcc
    10741 tttccagcaa tatacggaag caccgcaacc gggtatcctg gtaaccaacc cgccttatgg
    10801 cgaacgtatc tcctcccgcg acctgctggg actttataat atgatcggcg aacgcgtcaa
    10861 acatgtgttt accggatata aagtatggat actcagctac aaagacgaat gtttcgacaa
    10921 gatcggcctg cgtcccagcg aacggatgaa gctgatcaac ggctcgctcg actgcgaata
    10981 ccgttgttac gaaatatttg aaggaaagaa caaagactat aagaaagcat tgaacgagga
    11041 aggcgcggaa agaacggaag attccgcctc acgcccaagg ccctcgttcc ctgaaaaaag
    11101 atatgacacc cgtcctgcag gtcgcccgaa cttcaagacc gaccgcatgg accgccccga
    11161 ccgtcgtttc gccgctgctc acagtgaaga cgaaaacgaa cgtacatccg cagcaccggg
    11221 aaaacgtttc ttcggtgaag aacgcggtga cggccgtcct gcccgcaaac agttcggagg
    11281 cgaacgtggt gaacgcccgg ttcgtccgat tttgcacaaa gccggtgaaa aacgccccgt
    11341 caaaatgcgt tacaaagacg aagacgacag gttctctaaa aacagaaaga acttcggaga
    11401 cagaaaacgc ggagaaggcc gtccattcaa gaaaccattc agaagagaag acaacgatga
    11461 ctttgaagat taaacacttc ctggttcttt gcgtgttcgc tttatctaca tccatgacgc
    11521 tgatggcaca ggacaaacaa ctcacattac acgacctgct tccgggaggg aagacacaca
    11581 ataagttcgt cccggccagt ctcaaacagc tacaatggtg tggggacact tacctgtatg
    11641 tcaaaggaga cagtatgata tgcnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    11701 nnnnnnnnnn ngacttccga cggtaggcag cctgcccgga ttttcggttc cctataagga
    11761 ccagccggta ctggctttta ccagtaaagg ccaccgcctg cattacaatt ttgccgaaaa
    11821 caagataatt ggcaattatc agctggacag caaaggatcg aactataact tctgtccggc
    11881 caataactgc ctggcattca cggtggggaa caacatacag attctttcac cggagaatca
    11941 gacgagtatt gttacacgtg aaacaaaaga tggaatcgtc tgcggacagg cagtccatca
    12001 acgtgaattc ggcatcagca aaggactgtt ctggtcaccg gcaggttccg ccctggcttt
    12061 ctaccggatg gacgagagca tggtcacaga ctatcctatc gtcaatatcg acgcccgcca
    12121 ggcaaaagcc gaaccggtta aatatccgat ggccggcatg aagagccatg aggtaacagt
    12181 cggtgtgtac aacctctcga caggcgaaac cgtctggctg gaaaccggaa ccccgaaaga
    12241 aaagttcctt accaacatcg cctggagccc ggatgaaaag agtatctata ttgccgaact
    12301 gaaccgcgaa cagaatgaga tgaacctggt tcgctattct gccctgaccg gcaagaaaga
    12361 agccgtcctt ttcacagaaa cgaacgaaca ttacgttgaa ccgcaatatt cggtactctt
    12421 cctcccgaac gatcccggca aattcatctg gcaaagccag aaagacggat acaaccacct
    12481 gtatctgtat gacaccaccg gcaaacaact aaagcaactg acacagggag aatgggtagt
    12541 cacccaggta atcggtttcg atgccaaagg cgagaacctg tttatcactt ccacccaacc
    12601 gcacatacgg agttcgttca attacggcac tccgatgaat gtaaacggct ggaagctgaa
    12661 tctgaagaag ggggagacat ccctgctgac accgaatgcc gccctggaaa gtgtacataa
    12721 cctttcggtc agcgcctccg gcaaatatgc gatcgacagt tacgacgctc cgaaaatccc
    12781 gcgcatcatc aacctgatcc ggaccaaaga cggcaaggag atcaaaaacc tcctgaccgc
    12841 ccgggaccca tacaaaggct acacactgcc ggaaatagaa gctggtacca taaaatctgc
    12901 cgacggtaca accgacctgc atttccgcct ggtcaaacct gtcggactgg atgagaacaa
    12961 gaaatacccg accatcgtct acgtctacgg tggcccccac tcacaactgg taacgggcgg
    13021 ctggcagaac ggcgtaagag gctgggatat ctatatggca caacgcggct atgtggtttt
    13081 cacggtcgac aaccgcggca catctaaccg gggattcgct ttcgaaagcg tgatccaccg
    13141 caacctgggt gtcaacgaga tggccgacca gatgaaaggc gtggaatacc tgaaatcgct
    13201 tccttacgtg gatgccgacc gtatcggtgt gcacggatgg agctacggcg gcttcatgac
    13261 gaccaacctg atcctgacgc atcccgatgt tttcaaagtc ggtgttgccg gcggtccggt
    13321 gatcgactgg agcaactacg agatcatgta tggagagcgt tatatggacc gtccgcaaga
    13381 taatccggaa gggtataaga acgccaacct gaagctgaag gcaggcaacc tgaaaggcca
    13441 tctcctccag atacacggcg acatcgaccc ggtagtagta tggcaacata gcctgggctt
    13501 cctgaaagcc tgcgtggatg cagataccta tcccgattat ttcgtctacc cccgccacga
    13561 gcacaacgtg acaggcaaag accgcccgca tctctacgag aagataacac ggtatttcga
    13621 tgactacttg aagaatacga acaaagagta actgtttccc ctcttgagag gggaaacagt
    13681 taccatcaga taatataata aacataacga tatgaacatt ctattattag
//
