LOCUS       gnlProkkaHKOPHDEH_188   6349 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HKOPHDEH_188.
ACCESSION   gnlProkkaHKOPHDEH_188
VERSION     gnlProkkaHKOPHDEH_188
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 03:17:17
            Original ID  :: gnl|Prokka|HKOPHDEH_188
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6349
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..534
                     /locus_tag="ctg188_1"
                     /transl_table=11
                     /translation="MQELSFTIDRKHLELLDADMKWVVEPGDFVLMAGASSEDIRLNGT
                     LTVEDYQTRAKAIEAQKPAKRVSASTNPEDAENVLDEKINTAWQGNKGDYITFALKNGA
                     KVDKVAIAFTRDNNLPATFEIQLSGGGGQFLTVYSGTVSEYGKLISYPFKGTTASDLRI
                     VLNDDRVSIAEVKF"
     protocluster    1..6349
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2890:3244]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2891..3244
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..6349
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6349
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             636..1763
                     /locus_tag="ctg188_2"
                     /transl_table=11
                     /translation="MKTLLFCMLGLGLTACGSSPKGTNGDQDELAMLIGTYTNGSSKGI
                     YTFRFNQETGTAVPLSSAALPNPSYLVPSEDGEFVYAVSEMNDSTAALSSLAFDRETGE
                     LRLLNTVPTFGADPCYVATNGREVLTANYSGGTMSVFPLQKDGTLAPADTLFQGSATGP
                     DAIRQATPHIHCTVFSPDGKYIFATDFSADRILRFVMHPDDPIPHASLEAVDIEADSGP
                     RHLTFSPNGKFAYLITELSGKVIAFSYDDGCLEQIQTITADTVAARGSADIHLSPDGKY
                     LYASNRLKEDGIAIFAVNPENGTLAKVGYQPTGIHPRNFNITPNGKYLLAACRDSNVIQ
                     VYKRNEVTGLLEDTHQDIVVDMPVCVQFVSSVNNL"
     CDS             1834..2883
                     /locus_tag="ctg188_3"
                     /transl_table=11
                     /translation="MKKNILMLSALFLSITAMAQTDVTTGVMRGKDYGVTYMLPKTEIE
                     IVLQATKHTYTPGEFCRYADRYLRLNNVSAEPEEFWTLDKIETRIAGVPDKDNVYFVKM
                     KDKTVAPLMELTEDGIVRSINIPFSGKPAAKTPEAKATESSIDPRSFLTEEILMSNSSA
                     KMAELVAKEIYSIRESKNALLRGEADNMPKDGAQLKLMLDNLNQQETAMTEMFSGKIKK
                     EPKTFTIRLTPKEMKDEVAFRFSRKLGVVANNDLAGEPYYISVTDLKSPDVSATEEGKK
                     KVDGVAYNLPGKAQVTLMYNNKKLFDDQLPITQFGTVEYLAPVLFNKNSTIKVLFDTAT
                     GGLIKVDRE"
     CDS             complement(2891..3244)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg188_4"
                     /sec_met_domain="PqqD_RRE (E-value: 7.2e-11, bitscore:
                     30.9, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.3e-17, bitscore: 53.1,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMEIPEGKVSLLDAVPVRCGHITTEWEGECAVLAYPRFKYEWMRR
                     FLLPKGMSPDIHVRLEEHGTAVWNLIDGHRTVREIISLLARHFGEEENYIPRVTAYVMQ
                     LRKDGFIQLTIRN"
     CDS             complement(3264..4655)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 102; E-value: 4.6e-31)"
                     /gene_kind="transport"
                     /locus_tag="ctg188_5"
                     /transl_table=11
                     /translation="MTEQLKLKLNDSKATRWGALVIVAFTMMVAYYVNDVVAPLKTMLE
                     TDLAWSSTDFGFFTGGYSFLNVFFLMLIWGGLILDRFGIRFTGKLATILMVGGTALEYY
                     AMTGLAGADATLFGINEIFGYKTGVFVAFAGYSIFGVGAEVAGITVSKIIAKWFKGKEL
                     ATAMGVQVALARIGSQAGYAVAIPLARAFGISTPVLLGLVLLLGGMIAFFIFAVMDKKL
                     DKQMEAAAIAAGTEDEEEKFSFKDVKNILVNPGFWLIALLCVLFYSCVFPFQKFASELM
                     IIKYGINENVAGTFAGLPALGALILTPVFGGFIDKRGKSASIMLLGSAMLICVHFIYAI
                     PDINYWLVAIVLMIILGIAFSLVPSAMWPAVAKIFPVSQLGTAYALIFFIQNIGLWGIP
                     TLIGWVLDAYCISGKKPDGTNMYDYTVPMCIFTGIACLSLIVALLLKKADKKYGYKLEE
                     PNIQK"
     CDS             complement(4809..5198)
                     /locus_tag="ctg188_6"
                     /transl_table=11
                     /translation="MYLLLVILMLIASVLMCFIVLIQNSKGGGLASGFSSSNQIMGVRK
                     TTDFLEKATWTLAAVMVVFSIVSAYTIPSSTGKGGDVILEQAQQEEKTNPYNMPVGTEA
                     PQSEAPAATTPAETPAPAAEAPAAE"
     CDS             complement(5203..5976)
                     /locus_tag="ctg188_7"
                     /transl_table=11
                     /translation="MTPTHLQQWIQHPETLNRDTLYELRTLVARYPYFQSLRLLYLKNL
                     YLLHDINFGAELRKAVLYVADRRVLFYFIEGDRYTLKSRKVSSLFSGDLEKEPSVDRTL
                     SLIDAFLATVPEEHSQHTELDYAVDYTAYLMQEEPGVDAEDESEVPKLRGHELIDDFIQ
                     NSESSDASDTRREFLVEKEEETEEEEEPSVSPVTEELDDSCFTETLAKIYIKQHRYDKA
                     LEIIKKLSLNYPKKNAYFADQIRFLEKLIINAKSK"
     CDS             complement(5981..6349)
                     /locus_tag="ctg188_8"
                     /transl_table=11
                     /translation="MYVYAPLATEFNQKMKDMFIQQTRLQLVNSGGDLEIDGEITGYNQ
                     YNESVDASGYSSKVKVTLTVNVRYTNNTNHEEDFEQQFSAFQTYDSSKLLTEVQDQLIT
                     LMVKDIAEQIFNATVANW"
ORIGIN
        1 gcccaggagc tgtccttcac catcgaccgc aagcacctgg agcttctgga cgctgacatg
       61 aaatgggtgg tggaacccgg cgacttcgtg ctcatggccg gcgcctcttc cgaagacatc
      121 cgcctgaacg gaacgctgac cgtagaagac taccagaccc gtgccaaagc cattgaagcc
      181 caaaaaccag caaagcgtgt gagtgccagc accaacccag aggatgccga aaacgtgctc
      241 gacgaaaaaa tcaataccgc atggcaagga aataagggag attatattac ctttgcctta
      301 aagaacggag ccaaggtaga taaagttgcc attgccttta cacgtgacaa caacctgccg
      361 gcaaccttcg aaatccagct ctcgggcggt ggcggacagt tcctcaccgt atattcgggc
      421 accgtcagcg aatacggcaa actgatttcc tatccgttca aaggcactac cgccagcgac
      481 ctccgcatcg tgctgaacga tgaccgcgtc agtattgccg aagttaaatt ttaatgtgct
      541 aatgtgccaa tatgctaatg taccaatgac catgcagcat atacagcgca gccaattagc
      601 acattagcat attggcacat taacacatta aattaatgaa aacacttctt ttctgtatgc
      661 tcggattagg tttgacagca tgtggctctt ctccaaaggg cactaacggt gaccaggacg
      721 aactcgccat gctaataggt acttacacga atggctcaag caagggtatc tataccttcc
      781 gctttaatca ggagacggga acagccgttc cgctcagttc agcggcattg cccaatccct
      841 cctacctcgt cccctcggaa gatggcgaat ttgtctatgc cgtcagtgaa atgaacgaca
      901 gcacagcagc cctcagctcc cttgccttcg accgggaaac gggagaactg cgcctgctga
      961 acaccgttcc caccttcggc gccgacccct gctacgtggc caccaatggc cgggaagtgt
     1021 tgactgccaa ctacagcggt ggaaccatgt ccgtctttcc tttacagaaa gacggcactt
     1081 tggctcctgc agacacgctc tttcaaggct ctgccaccgg tcccgacgcc atacggcaag
     1141 ccactcccca catccattgc acggtctttt caccggacgg aaaatacatc tttgccaccg
     1201 acttcagtgc cgaccgcatc ctgcgctttg tgatgcaccc cgacgaccct attcctcatg
     1261 cttctctgga agccgttgac attgaagcgg attccggccc gcgccatctg acattcagcc
     1321 ctaacgggaa gtttgcctat ctcatcaccg aactgtccgg taaggtcatt gccttcagtt
     1381 acgacgacgg ctgcctggaa cagatacaga ctatcacagc cgacaccgta gccgcccgtg
     1441 gaagtgcaga catccacctc agtccggatg ggaaatacct ctacgccagc aaccgtctga
     1501 aagaagacgg catcgccatc tttgccgtga atcccgaaaa tgggaccttg gcaaaggtag
     1561 gttatcagcc caccggcatc catccccgca acttcaacat cacgcccaac ggcaaatact
     1621 tgcttgccgc ctgccgcgac agcaatgtca ttcaggtata caaacgaaac gaagttaccg
     1681 gactcttgga agatactcat caggacattg tagtcgacat gccggtttgc gtacagttcg
     1741 tcagctctgt taataattta taaagcaata tttagcaaag ataacttcat taactttgtc
     1801 ccttagctaa atcagtctaa acgaatgtac attatgaaga agaatatatt gatgctctca
     1861 gctctgttct tgtctatcac tgccatggcg caaacagacg taaccaccgg tgtgatgcgt
     1921 ggcaaagact acggagtgac ttatatgttg cccaaaacag aaatagaaat cgtattgcaa
     1981 gccaccaagc atacctacac tcccggagaa ttttgcagat atgccgaccg ctatctgcgt
     2041 ctcaacaacg tgtctgccga acccgaggag ttctggacac tggataagat agaaacccgc
     2101 atagccggtg taccggataa ggacaacgtc tatttcgtga agatgaaaga caagaccgta
     2161 gcacccctta tggagcttac cgaagacgga attgtccgct ccatcaacat tccgttcagc
     2221 ggtaagcctg ctgccaagac gcccgaagcc aaagccaccg aaagcagcat tgacccacgc
     2281 agttttctga cggaagaaat actgatgtcc aactccagtg ccaagatggc cgagctggtg
     2341 gccaaggaaa tatacagcat ccgcgaaagc aagaatgccc tcctgcgcgg cgaagcagac
     2401 aatatgccca aggacggcgc ccaactcaag ctgatgcttg acaatctgaa ccagcaggaa
     2461 acggctatga cggaaatgtt ctcgggcaaa ataaagaaag aacccaagac attcaccatc
     2521 cggctgacgc ctaaagagat gaaagatgag gtggctttcc gtttttcccg gaagctggga
     2581 gtggtggcca ataatgacct tgccggtgaa ccgtattata tcagcgtcac cgacctcaaa
     2641 agtcccgatg tatctgccac cgaggaaggc aaaaagaaag tggacggtgt agcctataac
     2701 cttccgggca aggcacaagt gacattgatg tataacaata agaaattgtt tgacgaccaa
     2761 cttcccatta cccaattcgg caccgtagaa tacctcgcac cggtactgtt caacaagaat
     2821 tctaccatca aagtgctgtt tgatacggca acgggaggat tgataaaagt agatagggaa
     2881 taaaggaatt ctaattccgg attgtcaact ggataaatcc atccttacgc aactgcatta
     2941 cgtaggcggt gacccgggga atataattct cttcctcccc aaagtgcctg gcaagtagag
     3001 agatgatttc gcgcacggta cgatgtccat ctatcagatt ccagacagct gtaccgtgtt
     3061 cttccagcct cacatggatg tcaggagaca tccccttcgg caataaaaaa cgacgcatcc
     3121 attcgtattt aaaccgtggg taggcgagta cggcgcactc accttcccat tcggttgtta
     3181 tatgtccaca gcggaccgga acagcgtcca acagacttac ttttccttcg ggtatttcca
     3241 tcatacggta tccgcttttc ctattatttc tgaatattag gctcttccag cttataacca
     3301 tacttcttgt ctgccttctt cagcagtaga gccactataa gggacaagca ggcaataccg
     3361 gtaaaaatgc acataggcac cgtatagtca tacatattcg ttccatctgg tttcttgccg
     3421 gatatacaat aggcatcaag cacccaccct atcaatgtag gaatacccca aagaccgata
     3481 ttctggataa agaaaatcaa tgcgtatgcc gtacccaact ggcttaccgg gaatatcttg
     3541 gccacagccg gccacatggc agaaggtacc agcgagaaag cgatacccaa aattatcatc
     3601 agcacaatag ctaccagcca atagtttata tcgggaatag cataaatgaa atgcacacat
     3661 atcagcatgg ccgagcccag cagcatgata gatgcggact tgccccgctt gtcaatgaaa
     3721 ccaccaaaga ccggagtcag aatcagcgct cccaatgccg gaagtccggc aaatgtaccg
     3781 gccacattct cattgatacc gtatttgata atcatcaact cggaagcaaa cttctggaat
     3841 gggaatacac aagagtagaa caatacacac agcaatgcta tcagccagaa accgggattg
     3901 accagaatat tcttcacatc cttaaaagag aacttctctt cctcatcttc cgtaccggca
     3961 gcaatggcag cagcttccat ctgtttgtcc agcttcttgt ccatcactgc aaagatgaag
     4021 aaagcaatca taccgcccaa caacagaacc aaacccaaca acaccggtgt ggaaataccg
     4081 aaagcgcggg ccaaaggaat ggctacggca taaccggctt gcgaaccgat acgtgctaaa
     4141 gcgacttgta cccccatagc cgtggcaagc tctttcccct taaaccactt ggctatgatt
     4201 ttggaaactg taataccggc gacctccgct cctactccaa aaatggaata accggcaaaa
     4261 gcaacaaaca cacccgtttt atagccaaat atttcattga ttccgaataa agtcgcgtcg
     4321 gcaccggcaa gtcccgtcat tgcatagtat tcaagtgctg taccacctac catcaggata
     4381 gttgccagct ttccggtgaa acggatacca aagcggtcga ggattaatcc tccccaaatc
     4441 aacatcagga aaaaaacatt cagaaaacta taaccaccgg taaagaatcc gaaatcggta
     4501 ctcgaccaag ccaagtccgt ttccaacatt gtcttcaacg gtgctaccac gtcgtttaca
     4561 taataagcta ccatcatcgt gaaggcaaca atcaccaatg ccccccaacg ggtagccttg
     4621 gaatcattca atttaagttt gagttgttct gtcattgtac tatttggatt tcaatttatt
     4681 aatcagattg cataaattgc tgacaaaggt aaataaatac ttcatcaaaa cgaaaaaagg
     4741 ctgacacctt ttcagtatca acctttctct tatttttcca agcgggagtc atccgcaata
     4801 tccttatctt attctgctgc aggggcttct gctgcaggag caggagtttc agccggagtt
     4861 gtagctgcag gggcctccga ttgcggagct tctgtaccta cgggcatgtt ataaggatta
     4921 gttttttctt cttgttgcgc ctgttccaga atcacatcac cgcccttgcc tgtggaagaa
     4981 ggaatagtgt aagcagaaac aatactgaag actaccatga cagctgccag agtccaggtt
     5041 gctttttcca aaaagtccgt agtcttgcgc acacccataa tttggttgga tgatgaaaag
     5101 cctgatgcca gaccacctcc tttagaattt tgaatcaata caatgaagca catcagcaca
     5161 gatgcaatca gcattaagat aactaataat aaatacattt tgttattttg atttagcgtt
     5221 aataatcaat ttctccaaaa atctgatttg gtctgcaaag taagcatttt tttttggata
     5281 attcaaactt aattttttaa taatttcaag cgccttgtca tatcggtgct gttttatata
     5341 gattttggct aaagtttccg taaaacagct atcgtccaac tcttccgtta ccggcgatac
     5401 tgagggttct tcctcttctt cagtctcttc ctccttctct acaagaaact cccttctcgt
     5461 atccgaggca tccgaagact cactattttg gataaagtca tctatcaatt catgcccgcg
     5521 cagtttaggc acttccgact catcttctgc atccacaccg ggttcttcct gcattaaata
     5581 ggccgtataa tccaccgcat aatccagctc cgtatgctgt gaatgctctt cgggaacagt
     5641 agccagaaat gcgtcaatca aggaaagggt acggtccaca ctcggctctt tctccaaatc
     5701 gccggaaaac agcgacgaga ccttccggga tttcaaagta tagcggtcac cctctataaa
     5761 gtaaaacagc acacgacggt ctgccacata caacacagcc ttgcgcaact ccgcgccaaa
     5821 gttgatgtcg tgcagcagat agaggttttt cagatagagc aaacggagcg actggaaata
     5881 aggatagcgt gccaccaatg tgcgaagctc gtacaaagta tccctattca gcgtctcggg
     5941 atgctgaatc cattgttgca aatgggtagg cgtcatgagt ttaccagtta gctacagttg
     6001 cattgaaaat ctgttcggca atgtctttca ccatcaaggt tatcagctgg tcctgcactt
     6061 cggtcagcaa ttttgaggaa tcataggtct ggaaagccga gaactgctgt tcaaagtcct
     6121 cctcatggtt cgtgttattg gtgtagcgca cgttgacagt cagcgtcacc ttcaccttcg
     6181 aagagtagcc gctggcatcc accgattcat tatattgatt gtagccggtt atttctccgt
     6241 ctatttccag gtctcctccg gaattcacca gttgcaggcg agtctgctga atgaacatat
     6301 ccttcatttt ctggttaaat tctgttgcca gcggtgcata tacatactc
//
