LOCUS       gnlProkkaJAOAAGEL_19   15569 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JAOAAGEL_19.
ACCESSION   gnlProkkaJAOAAGEL_19
VERSION     gnlProkkaJAOAAGEL_19
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 03:50:00
            Original ID  :: gnl|Prokka|JAOAAGEL_19
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15569
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15569
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5302:5569]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5303..5569
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..15569
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15569
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             72..3650
                     /locus_tag="ctg19_1"
                     /transl_table=11
                     /translation="MMKLRNLMQVACMATAALTAFSCSQEEFENSGWKGNITVNATFEG
                     AGTDTRTTVNDEYKILWQDTDALGLFCSNAESNYSNTKLEYASGAGQTSATFNGSKPSG
                     ETAVFSIYPYQQNMSVSGNTLTMTLPATLTNYNGSSNGPMYAKVTNPDNLSALSFKHMA
                     AMIKLTVNKIPAEATTFKIIASNNIAGTCTVDLTAADPILAVTSDESKEITASFTASAD
                     IKSRNFYIPLPTGTYSSITAQLTNGSDKVYFTKTLNDKILGRRDILVVPPLDCVVVEAT
                     TPSALSTALADSKNLPQEAPTAATVTDIAVSGSFNTTSGSNDGIAIPVLQNSDINLAFN
                     TAPTTSTSAPLKLTDKTNTSVSTPAATATNSVSLAVPETTAEQEAPSVAITMPSTTVTL
                     AAVGNKATYNEVTATTAQQTLIINAGVTVKKLTVKGGNLKIYGKVEQLVHDAGNTTIYI
                     IKGTEASLPATIDSKFVVQSDVAVLKTAFANGEDFKLSADADITGQSVSVPAGKSVVLD
                     LNGYTLTADNSATGKIIVLGKMTLKDSSTEKKGKIVASQDYTAASYNGSLIEIAGEDAS
                     MTMESGNISAVRKTPNSNGQYGVGVTDGGDFTMTGGKIEAGWFAVAGNGNYKTQNSIIN
                     ITDGELISTADYAVYLPQSGTTTISGGKVYGAAGGVCIQRGTLNVEGTALITSKGTGST
                     GNWGDGTGGLDCAAINVSGAYGIATVNIKGGTLIAEAKSLITEGTTYTPVINVTGGTFS
                     DPSALKYMKTNANVNIKLTADKTCPGFKTTSGQTLTMDLGGKILTLADPTVGSTGTETN
                     SCQLLEGSNVTFKNGTLKSDNNKIMIQNYCNLTLDNMTVEDTNAQYVVSNNCGNISINN
                     TTINAGSNANQFAFDVCGYAKYTAGVTVTVSGTSVINGKVEISKSAGNTEPMKLNITGG
                     TFNGDLKVDASVGTENAKSIISVSGGTFSDPSVLKYMATNATVDIKLLSNINIAKTELA
                     TGYILNAANATANLNLNGHDIINSSETADATPFTQIFTVQNGTLNISGNGNVKCDASAT
                     AKDDGYRMVIEARGHGTVNIHGGSYYNTQKLNTQIDLIYARENGKINIYGGTFESGKYG
                     TPNNDTDGRYWVLNLKNTDKNTASIQVSGGTFINFNPANPNMDDNESYLVTGYEVTRDG
                     SVYTAAHKVNDGRKEYIVGPTSQENR"
     CDS             3897..4823
                     /locus_tag="ctg19_2"
                     /transl_table=11
                     /translation="MRIQILDYQVGPHTFRMVKPSDFNIFKALPSLIPFITTIDTTQKV
                     IFETEIDDDETATKRTIAKTPDDICFNWEDADCIIRPLPHSSHLVSITPRKSGKNYWME
                     CNDNFRQCFIHLPACRTETPAPENETNFVLNNFLMMLYAFNAARHHTLLMHASVVATET
                     GKGYLFLGKSGTGKSTHTGLWLQQFSDCHLLNDDNPIVHVDSLGKQATVFGSPWSGKTP
                     CYRKESMTVGAFVRLEQAPQNEIEQERAAHAFATLLPSCSCLKQNKEIYNAIVTTVTEL
                     ATLAPVYHLKCLPDREATELCRKTVEG"
     CDS             4850..5290
                     /locus_tag="ctg19_3"
                     /transl_table=11
                     /translation="MKKSIPNEILLPEVARLIKEGHTVTITVRGNSMNPFLVDRRDRVT
                     LGDFTTEQLQPGVAVLARDLTERIVFHRIIRRNGNILILQGDGNLAQTEETDIGRVMGV
                     MTEAMRKDKRYTADGKVWKLYSYWWMKLNPARRWLLALFRRI"
     CDS             5303..5569
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg19_4"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 7.9e-14,
                     bitscore: 41.0, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 3.7e-16, bitscore: 48.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKQGFILHRIGDDYIIMQDGSSNVDFSKVISLNQTSAMLWQEI
                     ENKEFDTDSVTEALTSRYDVDNESARRDAQKFIDSLDREGIIE"
     CDS             5578..6741
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg19_5"
                     /sec_met_domain="NTP_transf_5 (E-value: 7.5e-47, bitscore:
                     149.3, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQHAFFSLVRSGLWGTPADRQLFRSVSPDDWETVYRMANSQALLA
                     LTFDGISSLPAELRPPRALYLKWAARTAQIEQANKRLNQLLPELNTLYREAGLHPVLLK
                     GQGIGTNYRTPLHRQCGDIDIYLGKQGQPIANRLLLQQGAIVEGEASDKHASYSLKGVH
                     IENHRIILRLNSPLANRHFQQIIRKWYPQETDYALFSETGKEDSKAVSIAIPPATFNAL
                     YIFLHAFVHFLNSGIGLRQLCDWTCLLANRHKEIDATTLLRQLQDLGLLHAAQAFGYIA
                     VTRLGLPANRLPFPLEGTKQIGEQLLEDILSTGNFGQHDNRIKPRPKGYWAGKWYTFCR
                     ATRRCNELRQFAPYEALWYPVTLIGGTIAIQINRLKGVKDKKARTKK"
     CDS             6764..8434
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 275.5; E-value:
                     1.5e-83)"
                     /gene_kind="transport"
                     /locus_tag="ctg19_6"
                     /transl_table=11
                     /translation="MKKQQKDKKVKKDRREKLRYIREVSAEQRGRILLSCLTGILGVAF
                     ALAFIYATKRVIDTATGITDDNLTHVAVLTVVLLTAQLLCGAADTWISTRMQIETGNAL
                     RHRLFSRLLQSRWNELERFHTGDVVNRVEQDTAAIVTLLTSSVPAFIVTSIQLLAAFLF
                     FYFLDPSLPWLIVAILPVFLLGSRFYMRRMKRYTHDIRNSDGRIQSVIQESLQHRIVIK
                     TLEQGERHLDKLDDLQDMLHSQVMGRTRFSLSAHMLVALAFSGGYLTAFLWGAVHLSAG
                     CITFGTMTAFLQLVGKVQRPVLDLSRLIPSVVNALTAIDRLLELERLPAEADGDSIFLA
                     STPELELKDVTFGYTPDDRPVFSRFSCRFPAGSCIAVVGETGKGKTTLIRLLLALATPQ
                     EGQILLIPAKHPLETSHTVSPQTRKNFVYVPQGNTLFSGTIRDNLLMGNPQASEEAIYQ
                     ALQTATADFVFHLPDGVDSPLSERGGGLSEGQAQRIAIARALLRPGNILLLDEATSALD
                     PDTERLLIKNLRRDCAGKTCIFVTHHPAVAEACESIVRL"
     CDS             complement(8479..9390)
                     /locus_tag="ctg19_7"
                     /transl_table=11
                     /translation="MKPTLFLLAAGMGSRYGGLKQLDGLGPNGETIMDYSIYDAINAGF
                     GKLVFVIRKDFEQDFRDKIISKYEGHIPCELVFQSIDDLPEGFTCPEGRTKPWGTNHAV
                     MMGADVIKEPFAVINCDDFYGRDSFQVMGKFLAALPEGSKNVYSMVGFRIGNTLSESGT
                     VSRGLCGTDANNLLTSVVERTKIQRMDGEVKYIDDNGEWTATPETTPVSMNFWGFTPDY
                     FAYSAEFFKSFLSDPKNMENLKSEFFIPLMVDKLINDGTATCEVLDTTSKWFGVTYPED
                     RQSVVDKIQALVDAGEYPAKLF"
     CDS             complement(9517..11871)
                     /locus_tag="ctg19_8"
                     /transl_table=11
                     /translation="MKRLILYIAGLIFLAGCSTTKHLPQGEILYTGQKPMIVLNRSETS
                     VGEIAMEEVEAALATAPNNSLLGSSTIRYPFPFGLWIYNGFQKYEKGFGKWIFNKFAAT
                     PVLMSTVNPDIRQKAAVNLLRDYGYFNGSVSYKTFIDPKDSLKAKLQYTVNMRNPYFID
                     TVYYRGFSERTTRIMELGRRRSLISSGEQFNVADLDGERTRISTLLRNVGCYYFRPDYL
                     TYQADTMMVPNGHVQMRLIPVPGMPKVAEKQFRVGRKSVYLLGKQGQEPNDSMDYKGLT
                     IHYYNKPPVRPNMLYRWLNYQGYRRKRQIQDSAGIARQRSMQSLYSLYRQTRIQERLAS
                     VGIFRYAEMQYIPRDTAFVSDTLDVRVIAALDKPYDAELDFNVTMKSNNQTGPGAAFTV
                     TKNNVFGGGESWNVKLNGSYEWQTGKASSSLMNSYELGISTSLIFPRVVFPRMGDREYD
                     FPATTTFRLYADQMNRAKYYKLLAFGGNVTYDFQPKSTSRHSITPFRLTFNVLRNPTAA
                     FDTLRAENPALYVSLRDQFIPAMEYTYTYDNASVRGKRNPIWWQTTVASAGNLTSAVYR
                     IFGKPFSEEGKKLFGVPFAQFLKLNSEFRYHYRIDKNQMIASRIAGGVIWSYGNATTAP
                     YTEQFYIGGANSVRAFSARSIGPGGYPPETDRKYTYINHVGDIRIEANIEYRFRMIADL
                     HGAVFLDAGNVWLMRKDENRPDGEFTLKNFPKQIALGTGFGLRYDLDFLVFRLDLGIGL
                     HDPYDTGKSGYYNIPKFKDSMALHFAIGYPF"
ORIGIN
        1 tcagacgtgt gctcttccga tctacctaat caatgacatc ttaaccgtag aaaactaagg
       61 gggacttcat tatgatgaaa ttaagaaacc ttatgcaagt tgcctgcatg gcaactgctg
      121 ccttgaccgc attcagttgc agccaagagg aatttgaaaa cagcgggtgg aaaggaaaca
      181 tcaccgttaa cgcaacgttt gaaggcgcag gtaccgacac ccgtactacc gtaaacgatg
      241 aatacaagat tctatggcaa gataccgatg ccctagggtt gttctgtagt aatgcagaaa
      301 gtaattatag caatacaaaa ttagaatatg caagcggtgc tggtcaaact tccgccactt
      361 tcaacggcag caagccaagc ggagaaacgg ctgtattctc catctatcct taccaacaaa
      421 acatgagcgt aagcggcaat acattgacca tgactctacc tgccacgctt acaaattata
      481 acggcagcag caatggcccg atgtatgcca aggtgacaaa tcccgacaat ctgagcgctc
      541 tgtccttcaa gcacatggca gccatgataa aactgaccgt caacaagatt ccggcagagg
      601 ccactacttt caagattatt gcctccaata acattgcagg tacttgtacg gtagacttaa
      661 ccgcagcaga cccgatactg gcagtaacga gcgatgaaag caaggaaatc accgcctcct
      721 tcacagcctc agctgatata aagtctcgca acttctacat tcctttgccc acaggtactt
      781 atagttccat cactgcccaa ctgacgaatg gaagcgacaa ggtatatttt accaagacgc
      841 ttaatgacaa aatcctaggc agaagagaca tattggtagt acctcctttg gattgcgttg
      901 tggtagaggc tacaaccccc agtgcgctta gtacagcttt agctgattca aaaaatctcc
      961 cacaagaagc accgacagca gcaaccgtaa ccgacattgc agtcagcggc agcttcaata
     1021 ccacttctgg cagcaacgac ggcatcgcca tcccggtttt acagaactcg gacatcaacc
     1081 tggcgttcaa tacagccccg acaaccagca cttctgcccc gttaaagctg accgacaaga
     1141 ccaataccag cgtaagtact cccgccgcca ctgccaccaa cagtgtatcc ttggctgtgc
     1201 cggaaaccac agcagagcaa gaagctcctt ctgtagccat caccatgcca agcaccaccg
     1261 ttacattggc agcagtaggc aataaagcca cttacaatga agtgactgcc actaccgccc
     1321 agcagacatt gattatcaat gcaggcgtca ccgtaaagaa gctgaccgta aaaggcggta
     1381 acttgaagat atatggaaag gtagaacaat tggtacacga tgccggcaat accacaatct
     1441 atataataaa aggaactgaa gcatcacttc cggcaacaat cgacagcaaa tttgtagttc
     1501 aatccgacgt ggcagtccta aagaccgctt tcgccaacgg cgaagatttt aaattgtccg
     1561 ccgatgccga catcacaggg caaagcgtca gtgtacccgc cggaaagtcc gtggttcttg
     1621 acttgaacgg atatacactg actgccgaca acagcgcaac aggcaaaatc atcgtcttgg
     1681 gcaagatgac actgaaggac agctctaccg agaagaaagg caagatagtt gccagccagg
     1741 attatacagc ggcttcttat aatggcagtc tgattgaaat agccggtgaa gatgcctcca
     1801 tgaccatgga aagcggcaac atcagtgcag tcagaaagac tccgaacagt aacggccaat
     1861 atggcgtcgg agtgacggac ggtggagact tcaccatgac aggcggcaag atagaagccg
     1921 gatggtttgc agtggcaggc aacggcaatt acaagacgca gaactccatc atcaacatca
     1981 cagacggaga actcatttct actgctgact atgcagtcta tctgccccaa tccggcacaa
     2041 cgaccatcag tggcggcaag gtttatggtg ccgcaggagg tgtatgcatc caacgaggca
     2101 ctctgaacgt ggaaggcaca gccttgatta ccagtaaagg cacaggcagc accggcaact
     2161 ggggcgacgg taccggagga ctggactgcg ccgccatcaa cgtaagtgga gcatatggca
     2221 ttgccacagt aaacatcaaa ggcggtacac tgattgccga agcaaagtca ctcatcacag
     2281 aaggcaccac ttatacaccg gtcatcaacg ttaccggcgg tacattctcc gacccaagcg
     2341 cgctgaagta catgaagaca aatgcaaatg tgaacataaa gttgaccgcc gacaagacct
     2401 gcccgggatt caagaccaca agcggacaaa ccttgacgat ggacttaggc ggcaagatcc
     2461 ttacacttgc tgacccgacc gtaggttcca ccggcaccga aacgaacagc tgtcaattac
     2521 tcgaaggttc aaacgttact ttcaagaacg gaacgctgaa gagtgacaac aacaaaatca
     2581 tgattcagaa ctactgcaac ctgacattag ataatatgac agtagaagac acaaatgccc
     2641 aatacgtagt aagcaacaat tgtggcaata taagcatcaa caataccact atcaacgcag
     2701 gaagcaatgc gaatcaattt gcattcgacg tatgcggcta tgcaaagtac actgctggag
     2761 tcacggttac ggtaagcggt acgagcgtca tcaatggaaa agtggaaatt tccaagagtg
     2821 caggaaatac cgaacctatg aagctgaata tcacaggcgg tactttcaac ggtgacttaa
     2881 aggtagatgc atccgtggga accgaaaatg ccaaaagtat catctctgtt tccggaggta
     2941 cattctccga cccaagcgta ctgaagtaca tggcaaccaa cgcaactgtg gatataaaac
     3001 ttctctcaaa tatcaacatc gccaagacgg agcttgccac aggctacata ttgaatgctg
     3061 caaacgcaac ggcaaactta aacctgaatg gccacgacat catcaattcc tcagaaacag
     3121 ctgatgccac tcctttcaca caaatcttta ctgtacagaa cggaacacta aacatttcag
     3181 gcaacggcaa tgtgaagtgc gatgcatctg ctacagcgaa agacgatggt tatcgcatgg
     3241 taattgaagc ccgaggacac gggacagtaa atattcatgg cggttcttac tataacaccc
     3301 agaaactgaa cacccagata gacctgattt atgcaagaga gaatgggaaa atcaatatct
     3361 atggaggaac atttgaatcc ggcaaatatg gtacacccaa caacgacacg gatggcagat
     3421 actgggtact gaacttaaag aatacagaca agaacactgc cagcatccag gtgtccggtg
     3481 gaacgttcat caatttcaac ccggcaaatc cgaatatgga cgacaatgaa tcctatttgg
     3541 taacaggtta cgaggttacc cgtgacggca gtgtatatac agcagcccac aaagtcaacg
     3601 atgggaggaa agaatatatt gttggcccaa caagtcagga gaaccgataa gccaaattct
     3661 aagaaaggaa gcaatatatc ctcgcagacc aaacgaagag gtatcggaat cgacttatta
     3721 ctatctttta gatgcggcgg acagcggatt ttcttttata aatctgcgtc ctccgcgtct
     3781 aaaaaatgac aacaagacag ttgaaaaatc tctcaaatct tcctcattca cacaaacatt
     3841 cattattttt ctgagtagcc caaagtatca tgaataacaa ctaacaatca aaacatatga
     3901 gaatacagat attggattat caagtaggac cgcacacctt ccgcatggtg aaaccttccg
     3961 acttcaatat attcaaggcg ttgccttcac tgattccgtt catcacgaca atagacacga
     4021 cgcaaaaagt aatctttgaa acagagatag acgatgacga aacagcgaca aaacgaacca
     4081 tagcgaaaac tcccgatgat atatgtttca actgggaaga tgccgattgc atcattcgcc
     4141 ctttgcccca cagctcacac cttgtatcca tcaccccacg gaaaagcggg aaaaactatt
     4201 ggatggagtg caacgataac ttcaggcaat gcttcatcca cctaccggcc tgcaggacag
     4261 aaacaccggc tccggaaaac gaaacgaact tcgtactgaa caacttcttg atgatgctct
     4321 atgccttcaa tgccgcccgc caccatacac tgctgatgca tgcctcggtt gtcgctactg
     4381 aaacaggcaa aggctacctc ttcttaggga aaagcggcac gggcaaaagt acgcacaccg
     4441 ggctctggct gcaacagttc tcggactgcc atctactgaa cgatgacaat ccgatagtac
     4501 atgtggacag cctcggcaag caagccactg ttttcggttc tccgtggagc ggaaagacac
     4561 catgctatcg gaaagaatcc atgaccgtag gcgccttcgt ccgcttggaa caagcaccgc
     4621 agaatgaaat agagcaagag agagcagcac atgctttcgc caccctcctc ccctcctgct
     4681 cttgcctgaa gcagaacaag gaaatctata acgccattgt caccactgtg acggaacttg
     4741 ccacgctggc acccgtctat catctgaaat gcctgcccga ccgtgaagcg acggagcttt
     4801 gcagaaagac ggtagaagga taagttatga atgatgaact gaacagccga tgaagaaaag
     4861 cattcccaac gagatattgc ttcccgaagt ggcgcgtctc atcaaagagg ggcatacagt
     4921 aaccatcacc gtgcggggca acagcatgaa tcctttctta gtggaccgcc gtgaccgggt
     4981 gacactgggc gatttcacca cagaacagct gcaaccgggc gtcgccgtac tggcacgcga
     5041 cctgacggaa cgcatcgtct ttcaccgcat catccgtcgg aacggaaata tactcatcct
     5101 gcaaggcgat ggcaacctcg cccagaccga agaaaccgac atcggacggg taatgggcgt
     5161 catgaccgaa gccatgcgaa aagacaaacg gtacaccgcc gacggcaaag tctggaagct
     5221 ctactcctac tggtggatga agctaaaccc tgctcgccgc tggctgctcg ccctgttcag
     5281 aagaatataa aacaaaataa ccatgaaaat caaacaagga tttatcctgc accggatagg
     5341 cgatgactac atcatcatgc aagacggctc gtcgaacgtg gacttcagca aagtcatcag
     5401 cctgaaccaa acttccgcca tgctttggca agagatagaa aacaaagagt tcgatacaga
     5461 cagcgtgaca gaagccctga ccagccgcta tgatgtagat aacgaatcgg cccgtcgcga
     5521 tgcgcagaag tttatcgact cccttgaccg cgaaggaatc atagaataag gacggatatg
     5581 caacacgctt tcttttcatt ggtacgctcc ggcctgtggg gcactccggc agaccgacaa
     5641 ctcttccggt cggtctcgcc ggacgactgg gaaaccgtgt accgcatggc aaactcacaa
     5701 gccctgcttg cactgacttt tgacggcata agcagtctac cggccgaact gcgccctcca
     5761 cgcgccctct atctgaaatg ggctgcccgg actgcacaga tagaacaagc caacaaacgc
     5821 ctcaaccagc ttctgcccga actcaatacc ctttaccggg aagccgggct gcatcccgta
     5881 ctgctgaaag ggcaaggcat cggcaccaac taccgcactc ccttgcaccg gcaatgcgga
     5941 gacatcgaca tctatttagg aaaacaagga caacccatag ccaaccgcct cctgctgcaa
     6001 caaggcgcca tagtcgaggg agaagcgtcc gacaagcatg ccagctacag tttgaaagga
     6061 gtacacatcg agaaccaccg catcatcctc cggctgaaca gtccgcttgc caaccggcac
     6121 tttcagcaga ttatcagaaa atggtatccg caggaaacag actatgccct attctccgaa
     6181 accgggaaag aggactcgaa ggccgtcagt atcgccatac ctccggccac cttcaatgca
     6241 ctttatatct tcctacatgc ctttgtacat ttcctgaaca gcggaatcgg cctgcgccag
     6301 ctatgcgact ggacttgtct gcttgccaat cgccacaaag aaatagatgc caccaccctg
     6361 cttcgccagt tgcaggacct cggactattg catgccgcac aagcattcgg ctacattgcc
     6421 gtcacccgac tgggattgcc cgccaaccgg cttcctttcc ccttggaagg caccaagcag
     6481 ataggagaac aattattgga agacatcctg tctaccggta acttcgggca acatgataac
     6541 cgcatcaagc cacgccccaa aggatattgg gcaggaaagt ggtacacctt ctgccgcgcc
     6601 acccgacgct gcaacgaact gcgtcaattt gcaccgtacg aagcactctg gtatcccgtg
     6661 actctgatag ggggaacgat agctatacaa ataaaccgat taaaaggagt aaaagacaag
     6721 aaagcaagga caaagaaata aaagaacccg gaaaataaaa ggaatgaaaa agcaacagaa
     6781 ggacaaaaaa gtgaaaaagg acagacgtga aaaacttagg tatattcgag aggtatctgc
     6841 cgaacaacgc ggacgtatcc tgctaagttg cctcaccggc attctgggcg tggcctttgc
     6901 cctagccttt atctatgcaa ccaaacgggt gatagacacc gctaccggaa taacagacga
     6961 caacctgacg catgtcgccg ttctcaccgt tgtcctgctg actgcccaat tactgtgcgg
     7021 agctgctgac acttggataa gtacccgtat gcagatagag acgggcaacg cccttcgcca
     7081 ccgcctcttc tcgcgcttac tgcaaagccg ctggaacgaa ttggagcgtt tccataccgg
     7141 agacgtagtg aaccgggtag aacaagacac cgccgccatc gtcacattgc tcacctcttc
     7201 tgtcccggca ttcatcgtca cgagtataca actgctggca gcctttctat tcttctactt
     7261 tttagaccct tcactgccat ggctgattgt tgccatcctg cccgtctttc tattaggcag
     7321 ccgtttctat atgcgacgaa tgaaacgcta tacacatgat attcggaaca gtgacggtcg
     7381 catccagtcc gtcatacaag agagcctgca acatcgcata gtgattaaaa cattggaaca
     7441 aggcgaacgg catctggaca aactcgatga cttgcaagac atgctccaca gccaagtcat
     7501 gggacgtacc cgtttctcgc tttccgccca catgttagtg gcccttgcct tttccggcgg
     7561 atacctcacg gcttttcttt ggggagccgt tcacctcagc gcaggctgta tcaccttcgg
     7621 aacgatgacc gcctttttgc aattggtagg aaaagtccag cgtcccgtgc tcgacctctc
     7681 acgcctgata ccttccgtag tcaatgccct taccgccata gaccggctat tggaattgga
     7741 aagactgccg gcagaagcgg acggtgacag catattcctc gcctctaccc cggaactgga
     7801 actgaaagac gtgacttttg gctacactcc cgatgaccgt ccggtattca gccgcttctc
     7861 ctgccgtttc cccgccggta gctgcatagc tgtagtcgga gaaacaggaa aaggaaagac
     7921 aacgctcatc cggctattgt tggcactggc aacgccacaa gagggacaga tactcttgat
     7981 acccgccaaa catccacttg aaaccagtca taccgtctct ccgcaaaccc gcaagaactt
     8041 cgtatatgtc ccgcaaggca ataccctttt cagcggaact atccgtgaca acctgctgat
     8101 gggaaaccca caagcttctg aagaagccat atatcaagcc ctgcaaaccg ccaccgccga
     8161 cttcgtcttc caccttcccg acggcgtaga ctccccactc agcgaacgag gtggcggact
     8221 cagtgaagga caagcccaac gcatcgccat tgcccgcgct ctgctacgcc ccggaaacat
     8281 tcttctttta gatgaagcca cttctgccct cgaccccgac acggaacggc tgttaataaa
     8341 aaacctgcgc agagactgcg caggcaaaac atgtatcttc gtcacccacc atccggcagt
     8401 agcggaggca tgcgaatcta ttgtccgatt ataatcagag aatgagcccc aacgggtatc
     8461 tgcctttggt taacaaactc agaacagctt tgcaggatac tcgcctgcat ccaccaaagc
     8521 ctgaatcttg tcgactacac tctgacggtc ttcgggataa gtcacaccga accacttgct
     8581 ggttgtgtcg agcacttcgc aggtagcagt gccatcgtta atcagcttat ccaccatcag
     8641 cgggatgaag aattcgctct tcaggttctc catgttcttc gggtcgctca agaaactctt
     8701 gaaaaactct gcactgtaag caaagtaatc gggagtgaaa ccccagaagt tcatgctgac
     8761 cggagtcgtc tcgggagtgg cagtccattc accgttatca tcgatgtatt tcacctcacc
     8821 gtccatgcgc tgaatcttgg tgcgttccac tacggaagtc agcaggttgt tcgcatccgt
     8881 tccgcacaat ccacgggata cggtaccgct ttcgctcaac gtgttgccga tgcggaagcc
     8941 taccatggaa tatacgtttt tggagccttc gggaagggct gcaagaaatt tacccattac
     9001 ctggaaggaa tcacgaccgt agaaatcgtc gcagttgata acagcaaacg gttcctttat
     9061 tacatcggca cccatcatta cagcatggtt ggttccccaa ggtttggtac ggccttcggg
     9121 gcaagtgaag ccttcgggaa ggtcatcaat ggactggaat accagttcgc acggaatatg
     9181 gccttcgtat ttggaaataa tcttgtcgcg gaaatcctgc tcaaaatctt tacggataac
     9241 aaacacaagc ttgccaaagc ctgcattgat ggcatcgtaa atagaataat ccatgatagt
     9301 ttcgccattc gggcccagtc cgtccaattg tttcaagcca ccataacggc tgcccatgcc
     9361 ggctgccaat aagaataaag ttggtttcat acttagttat tatttaaaaa ggttagtgta
     9421 tcacagttga taacggttgc aaatgtacaa aaatttatgg ctgacagaag ggagttttag
     9481 ttcattcttt accactatcc gttcaaaaag gtacatttag aacggataac cgatggcaaa
     9541 atgcaacgcc atgctgtcct tgaacttggg aatattataa taccccgact tcccggtatc
     9601 atacggatca tgcagcccga tacccaagtc cagacgaaaa acaagaaagt ccaaatcgta
     9661 acgcaagcca aatcccgtgc ctaaagcaat ctgtttcggg aaattcttca acgtaaattc
     9721 accatccggg cggttttcat ctttacgcat cagccataca ttgccggcat ccaagaatac
     9781 cgctccatgc aagtcggcaa tcatacggaa gcgatactcg atattggctt ctatgcgaat
     9841 atcacccacg tggttgatat aggtatattt cctatccgtc tcgggaggat agccgcccgg
     9901 acctatactg cgtgcagaaa aggcgcgcac actgttggca ccgccgatat agaactgttc
     9961 cgtataaggt gcggtcgtag cgttgccata cgaccatatc acccctccgg caatacgcga
    10021 ggctatcatc tggttcttgt ctatccggta atggtacctg aattccgagt tcagcttcaa
    10081 gaactgtgca aaaggtaccc cgaaaagctt ctttccttcc tcactgaacg gcttgccgaa
    10141 aatacggtag acggcagaag tcaggttacc ggccgacgca acggtggtct gccaccagat
    10201 ggggttacgc ttgccgcgca cggaagcgtt gtcataagta taggtgtact ccatggcagg
    10261 aatgaactgg tcgcgcaaac taacgtagag tgccggattc tcggcacgca acgtatcgaa
    10321 agcggcagta ggattgcgca gtacattgaa tgtcaaccgg aaaggagtta tactgtgcct
    10381 ggaagtcgat ttgggctgga agtcataagt gacattaccg ccaaaagcca acagcttata
    10441 atacttggca cggttcatct ggtcggcata taaacggaaa gtcgttgtag ccgggaagtc
    10501 atactcacgg tcgcccatcc taggaaacac cacgcgcgga aagataagcg aagtggagat
    10561 acccagttca taactgttca tcaaggaaga acttgccttg cccgtctgcc attcgtacga
    10621 accgttcaac ttcacattcc agctttcacc gccaccgaag acattgttct tcgtcaccgt
    10681 aaaagcggca cccggtcccg tctggttatt gctcttcatg gtgacattaa aatccaactc
    10741 cgcatcgtag ggtttatcga gcgcggcaat gaccctcaca tccaatgtat cagacacaaa
    10801 cgccgtatca cgcggtatat actgcatctc cgcataacgg aaaataccga cgcttgccag
    10861 acgctcctga atacgggtct gacggtacaa actatacaaa ctctgcatag aacgctggcg
    10921 ggcaatacct gcgctgtcct gtatctgacg tttccgccga taaccttgat agttcaacca
    10981 acggtaaagc atgttgggac gtaccggagg tttgttgtag taatgtatgg tcaagccttt
    11041 gtaatccatg ctgtcattgg gttcctgccc ctgctttcca agaagataga cggatttacg
    11101 ccccacacgg aactgcttct cggctacctt tggcataccg ggaacgggaa tcaagcgcat
    11161 ctggacatgc ccattgggaa ccatcatggt atcggcctga taggtcaggt agtcgggacg
    11221 gaaataataa cagcccacat tacgcagcag ggtactgata cgggtacgct ccccatccag
    11281 atcagccaca ttgaattgtt ctcccgaact gataagggaa cgtcggcgtc ccagctccat
    11341 aatgcgagtg gtacgctcgc tgaaaccacg ataatatacc gtatctataa agtaggggtt
    11401 acgcatgttc accgtatatt gcaactttgc cttcagcgag tccttcgggt cgataaatgt
    11461 cttgtagctg acgcttccgt tgaaatagcc ataatcgcgc agcaagttaa ccgccgcctt
    11521 ctggcgtata tcgggattca ccgtagacat aagcaccgga gtggcggcaa atttattgaa
    11581 tatccacttt ccgaatccct tctcatactt ctggaaacca ttgtaaatcc acagtccgaa
    11641 aggaaaggga tagcggatag tagagcttcc cagcaacgaa ttgttcggtg ccgtagcaag
    11701 ggcggcttcc acctcttcca tagcaatctc accaacagac gtttcactgc ggttcaatac
    11761 aatcatcggc ttttggccgg tatagagtat ctccccctgg ggcaagtgct tcgtggtgga
    11821 gcaacctgcc agaaatatca atcctgcaat atataatatc agtcgtttca tatcacattc
    11881 ctactttttc atatcgctat tttcagcctc cggttttatc tttttcttcc tgaagatgaa
    11941 gagttcactc aatcggtcca tcttccggcg cagcacaagg ccgacacccg tttcggttat
    12001 ctcaccgtcg agtatgcttt cgtagttttt attatggaat acacggacat atcgagtacc
    12061 cgacgcatca agacggtatt ccagcgatat attgtcaatg aatgattccg catcgttcgt
    12121 ggcattggcc ccggtggaca cttttccacc gatgactatc tgtacgcggt cgttgaagaa
    12181 acgctgggaa taacgaaaac tgaagtcttt ctgcgtgtca cccgtttcag cagaggtacg
    12241 gtcttccaca cctacactga tattggcccc ttttatacct cccgccaagg agtttatctg
    12301 gctctgaagc actgagttca aggcggctcc cattgacaaa cctcctcctt tggcaccact
    12361 gttcaggtaa atacccgtgg caagcatggc aatggcctgc ttgctacgct cttctgcacc
    12421 cattgcctgc agctcattct ctactgcggc atcttcgggc gccgaaatat cgaatatcaa
    12481 atcgggagcg tcaagcctgt tcttgatgga aatggaaaca tcgaagttca ccatgcgcga
    12541 accgtccccg tcaccatcgg ccacagaagc acgcatacgt tccgtagcct tcaggctcag
    12601 cgtaggattc ataatattcc cccgccaatc cacataactg ccgggattga actggaactc
    12661 cttcaacggg atgataggca gcgaatattt catgacgcca cccgaaaggg tatagcgtcc
    12721 ggtaaggctc atatcccctt ggggagtata ctgcatattc aaatcaccgc caccttccag
    12781 ttcgatgtat ttgctacggt cgggactcag atcggcacga agacggacag catcgtcaat
    12841 atggacggac atatacattt ccaatcctcc caaagacatg gcaggaacct catctgcttt
    12901 taccgacgtc gtatcggtga acgaggtaaa ggtaaccagc ccactgagac ggtcttccac
    12961 cgttaaaggg gaatcggtca acacgtaggt tacgttggta ttgcccagca aattcatgtt
    13021 tccacgcatc gtgagcccgt caagcggccc cttcaccgtg gcatgcaagt cgacgaacac
    13081 ctttccatac accagacttt cgcgggtacg cggtgcatcc agcaacgtat agttctctgc
    13141 cagcagattg aggttggcag taggacgctc catattccgg aaatcaacct taccgtcaat
    13201 cgtaaacgga ttcttgctgg tggtataaat ggcaaactta tcaaatatca actgattgtc
    13261 ctttatctgt accggacggt tgtcgaacca gtaacgtgct cccgcctggc gtgcatagac
    13321 agacacactg tccaaaacaa tatcaccatg catttgaggc ttgtccagcg aaccataaat
    13381 ataaagccct ccatcaatat ctccggtaaa ggccaccgtt tggtcaggga tgaatgcatt
    13441 ggccatcttc aatggaaaat gctcgaaacg ggtggacact tccagggtat cctttccgtt
    13501 cttctgcgtc aagataccgt cggcggtcat cacttcttca ttatcatatg taaaataggt
    13561 attcagatag tgcgtattct tgtcgcccgg caaccaggta gcccccaggc cgatgtctcc
    13621 aaccggttgg cgttcgtagg tcagtttctc tacattggct tcggcggaca cctgcaggga
    13681 agtggcagtc tgtatataat ttgcttcggc ggagaacaat cccgtaagcc ggggcatata
    13741 aggaagtacc tccgtaagtt catccaagcg caatcggctc agttctacgt ttatattctg
    13801 caaggaaagg gtatcattct tgtcggattg catacggaaa cacagaccat cgtcgctgtc
    13861 catatcaata ttggcataga cgcgcatatt cttatgcaga taaatccagt tactattgtc
    13921 cgcaaagtgg aatttacgga aagcgataat cggctcggca ggaataaggt tcagcagcac
    13981 accattaccg cgaccgtgtc cttcggtcaa cggacgggca ttaataccga atagaacacc
    14041 ggtctgccct tttccattca cataatccac agtcagttcc gcatcttcat tacggacttc
    14101 acccgtcagt gtgctacgga acacaaactg cgggttcttg ggaccgttta tgacaccacc
    14161 ttgcaacttc atgcgggcag tatcctgctt tactgtaaaa aatatcgtat cgagctgcaa
    14221 ggagtccatg cgcaatccgt gaacagctgt acgtccattg atgccgactt gcggagtaaa
    14281 tccgaagctc agtttgaaat cattatagga aatacccttt gcagccagga aatagctgac
    14341 gggattctgg ttaccggctt ccagatgcat gcccgctgaa ggaaggactt ggcgcaaagc
    14401 ggcatggtcc aaacgccgtt catcaatctg ctttgtcagg atagagacaa atttatccga
    14461 ctgttccatc aacttcttca acgtgctgtg agcgcggaaa cgcagattca agtcaccggc
    14521 atcaagcctc aacttgagag aatcatgacg tgcctccgct cccattgtaa aggcaaacgg
    14581 gtgtttcaat ggtcggggca ccaaacccag cttatgcaga ttcacctctt ccacatttaa
    14641 atccaaagcg ccatccagat agctgcggtc aagacgcata tccgcatttc cctgcatctt
    14701 gagaaggaca ttatcgctgg caagacggac ggtagcaacg gatgacttga gtccggcatg
    14761 cacatctaca ccggaaatgt cccaatggcc atactgtagt ttttccaagg aggcattcaa
    14821 agcggccaca gtttttcgtg atgccacatc caccccttgc cccttagcgg acatctttgc
    14881 cgtaagagta tagatagagt ccttgggcag gaagtgatgc acctgcaagt tgttgatggc
    14941 aaggtcggca tggtaggctt ccgtagcaag attataggcg gcgtccaaat tcaaggcgcc
    15001 ttccttctcc ttcagtttca gggcggcagt gcactgcgcc ccctccatac cgagacgtgc
    15061 cgcaaggtgc atactgtccg gcacaatgat ggagccatcg ggagcaatgt cagctagtcc
    15121 ggtcaggaag ttcaagttct gcgtatgcat ttcgaagtcc atgcttccat tacgtttcac
    15181 actgtcggtc aagctccaga attctcctcc cccactcaac gaaaaggctc cgggcagctc
    15241 agccgtaaaa cgggaaatct gcatctgctt caggtttcct tccgtaccgg catgaatcac
    15301 caacggacgg aacggatagg cttccttgaa agcttccggc aagccaccgg caaaaagcag
    15361 tacatcctgt ttgccgatac gggcattgaa acgggctgtc agacggccgg tggtaggtat
    15421 atttatcagt tcccagtaag tctgtgccgt aaggttcatc tcactatgag gtgtcagcaa
    15481 cttcaaagaa gggatacgga taacggtaga atcggcaaac aaccgcccgg tcagggaagt
    15541 tacactcaaa ccggaacgct catacatgg
//
