LOCUS       c00075_gnlPro..        14733 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IBDMOJGJ_75.
ACCESSION   c00075_gnlPro..
VERSION     c00075_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 12:00:03
            Original ID  :: gnl|Prokka|IBDMOJGJ_75
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14733
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..1080)
                     /locus_tag="ctg75_1"
                     /transl_table=11
                     /translation="MLQRKMLSFLFMMIFIPSVRAQWKDSTRFINKEHEFETTYNKISE
                     NKVYQMLRVPVPLFAISAITYGQGDKFRTLRNTHTPNFHYRYDDFLQYTPLLAVYGMKL
                     GGVESRSSWPRMIVSNAFSATIMAATVNSMKYTIKRERPDGSKNNSFPSGHTATAFMAA
                     TIMHREYGLTRSPLYSIGGYTVATATAFSRQLNNRHWLSDVLAGAGIGILSTELGYFLA
                     DLIFKDKGLNLPDKLRESAPKGGRPSFLEFAVGYSIINGSIEVGKNIRLSSPGATNVSV
                     KGGYFFNPYFGIGGEITALASPMAFDMSLYTGTTPSTKYDITRIHADPTGVFTFTAGPY
                     FSLPVASKLLLGTKFQAGYS"
     protocluster    1..14733
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1318:4816]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1319..4816
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14733
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14733
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             1319..2044
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg75_2"
                     /sec_met_domain="SucD_FumR (E-value: 2.3e-76, bitscore:
                     245.5, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSVSGLFLVLFLLFHLSMNVAAAFSGEAYNMI
                     CSLLGANWYAVAATLVLAAGVVIHFVYAVLLTLQNRKARGNDRYAINARPKGVEWASQN
                     MLVLGIIIILFMVLHFSQFWYKMMFAELLGNHMVTLCDGTTTVSPQDGAAFINYYFQGN
                     ILNTVLYLVWYVALWFHLTHGFWSAIQTIGWSNTIWMNRWICISKIVATVICVVFAIIT
                     IVFYLNGVGGDYVAVCAGH"
     CDS             2078..4033
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 195.7; E-value:
                     4.8e-60)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg75_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 1e-60, bitscore:
                     195.7, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 9.9e-39,
                     bitscore: 122.1, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQIDSKIPQGPLAEKWKNYKDHQKLVNPANKRRLDVIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRMIGLNKVKMYTRHEMLDVVKVDGRARGIIARNLITGQIERFSAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDYQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSDAINRLGKDVVKAKYGNLFDMYEEITNDDPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTXXXXIQNYLSDQIQVPRFSTDLPEFAEAEKGIKDRIKKLMSIKGKESVDSIHKK
                     LGHIMWEHVGMARDAKGLQEAIQMLKELKKEFWSNVYIPGEADNLNVELDKALRLADFI
                     EIGTLMAHDALDRAESCGGHFRTEHQTEEGEALRHDDKFMYVSCWEYQGEDKDPVMLKE
                     DLNYQFVVPQTRNYKK"
     CDS             4061..4816
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg75_4"
                     /sec_met_domain="Fer2_3 (E-value: 8.8e-27, bitscore: 83.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 2.9e-12, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.1e-06, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDIKVTLKVWRQKSPKDKGQFETYQIDKINQSVSFLEMLDILN
                     ERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANSIAIPRADAEMAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFICAKLQD"
     CDS             complement(5115..5960)
                     /locus_tag="ctg75_5"
                     /transl_table=11
                     /translation="MEDNIPKFDLPVDFIVGNSITGEILNQYGRFPCKIKAGIFVLCVQ
                     GTVHATVNLTEFTIRKNDFITLPPGCFIQIHEVSDDVKLCFAGFSSVFVSHINYIKTIT
                     NYLPVIFDSPIMPLPEHISLLYQQAFDLLINAYSMPKTIENKEIIKAIFTIFMQGVIEL
                     YRNHTPYSNAPMTRNMEICREFVQLAMENYTKEHSVSYYAKRLNITLQHFCYVIKKVSG
                     RTALDILSNIIIMDAKAQLKSTDMPVKKIAFALGFDNLSFFNKYFRQHVGMTPQEYRES
                     "
     CDS             6201..7415
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg75_6"
                     /sec_met_domain="Radical_SAM (E-value: 1.8e-14, bitscore:
                     44.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTKRTKSSFRTMSTNRKLESVFLFVTGRCNAKCKMCFYAEDMDK
                     KEKDLTFEEIKTISETAGQFNRLWVSGGEPTLREELPEIIEMFYKNNEIKDVNIPTNGL
                     KPDRIVAWVKQIRQNCPELNINLSLSLDGFGDTHDIQRGVPGNFYKAMGTLKLIEKNFA
                     DDGRVLKNLATVITKYNENEVEDLMIWMLGRFHLSNHIIEAARGMTRDDGVKVLTEPTL
                     RALQDKVVPIYNVYGERMAEETGGFRKPIARFFYLGFIRTLYNVRATNIDHPTPWGMDC
                     TAGETTLVIDYDGRFRACELREPLGNVKDYDCNIAKIMESDAMKQEIAAIGHGDKANCW
                     CTHGCWITSSLVFNPRKMITQVYKGYREMKKLNRPLNISEELLQSIERKYALDEQKLVE
                     LGVRN"
     CDS             7593..8177
                     /locus_tag="ctg75_7"
                     /transl_table=11
                     /translation="MTTKLKDLFDTFLNIAASSQKLGINLIRVAILIIFVWIGGLKFYN
                     YEAEGIVPFVANSPFMSFFYAKSAPEYKEYKLKEGEFNEAKHQWHVENNTYIFSHGLGI
                     MIMAIGILTFLGIFSPKIGLIGSGLAIIMTLGTLSFLVTTPEVWVPDLGSGEHGFPLLT
                     GAGRLVIKDTAIIAGAIVVLSDCAQRILKKK"
     CDS             8583..9332
                     /locus_tag="ctg75_8"
                     /transl_table=11
                     /translation="MNLRKNLFWAIPFIVVGVVWIMRNTGMITDDLFHIIVSWQMLVMY
                     IGIGSISRRHYIGGLITFLVGAAFLLPRLGWMDSDWLQVYWPAAFVIVGLMLIFEPRKK
                     NSYHYNSRREDTGGEDIRGNAVAGKVKSDFINTDGYVESDNTFGYVEQIILDPVFKGAR
                     IRTVFGGTVLDLRKTKLDSAKTYIDIDCKFAGVEIYLPGDWAVNFHGSPIMGACEDKRF
                     NASMEMDKEHILVVRGIVMFGGIEFKS"
     CDS             9335..10141
                     /locus_tag="ctg75_9"
                     /transl_table=11
                     /translation="MQTHPFINSVLCRMAGVALAVVSCSISALLLYYYGHTGWLVAWLD
                     SLVSVGIFCVSGFLFWYVTGILRPLQAQIALAVGVLIISVTGGYMAGALVYPDRMDWFA
                     STIPFRILLGLLGWIILAQWYYIRWKELQMEIQEEQRKEENAPAETGVSSPEEEAILDR
                     ISVKDGSRIHLIHLEELLYIQASGDYVALFTTDGQYIKDQTMKYFESHLPANLFIRIHR
                     SCIVNSEQIMRVELFGKESYQVRLKTGVCLRASLTGYKLLKERLSL"
     CDS             complement(10119..10310)
                     /locus_tag="ctg75_10"
                     /transl_table=11
                     /translation="MKKPQYKDKPETSVCQVFYRQYMLSLSGIVAKNCFRTQNFIQYRQ
                     KLLILTVKTAKSIEKDVL"
     CDS             10442..11662
                     /locus_tag="ctg75_11"
                     /transl_table=11
                     /translation="MEYIGLHEDKISLADIIKYLSLLKGNMDELNLLEFKTIKGWLVYS
                     LSLVLLLCIPCVIILLITGLLSGNIDSGLLLAVSFIPFLFILPLTLLLTFINNYRKPKK
                     LRELMQTVLMRYEWDGPINQTGRLQLECRKDHFLFRTEVLRQMNPKGRNVSLIFISVPF
                     YVPIEKELIHAEDIIAYLKGKSLFVIEPDMACLGMSFKMFQKLDLREDIDQLIYVMKRF
                     SLRPGTLFKAQDITLKVPETLEIQALFIFGQKIDQRFLNWANLMLDAGFVSDNMKIMAE
                     QASLTLPQKELKKRVEVIFLEFNLYFSKETVLNNYLIFLILEEQEERRSVLEIIQCLAS
                     LYQSSRLPLLQEYDLLYKAKRALDETGEQNFWTADPPLTVDNVDTYILTYLTRRLADLI
                     ASREKDQ"
     CDS             11841..14045
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_36C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_36N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Melibiase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg75_12"
                     /sec_met_domain="Glyco_hydro_36C (E-value: 2.3e-21,
                     bitscore: 66.0, seeds: 330, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_36N (E-value: 3.2e-49,
                     bitscore: 157.5, seeds: 284, tool: rule-based-clusters)"
                     /sec_met_domain="Melibiase (E-value: 1.3e-125, bitscore:
                     408.6, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKALLLTVALLLGCVTVSSQDKDTGIITVSTNDLSMVFSISPDKK
                     VVYNYFGDKFQDVSPFLHKKYKEQPDNGIGYAPVIYPAYGGRFFLNPALKLTHDDGVQT
                     TELIYAAHQVKNIDNNRIETVIQLKDPLYPVFVNLNFTAYQKENVICQSVSISHQEKNK
                     LAVENIASAYLPLHADSYYLTHFHGAWASEMQLVEEQLTPGVKRVESKKGIRTTQSENS
                     SFLLSLNGPANEDMGEVYAGSLAWLGNYLSSFEIDECGLLHVMSGMNDFASTYNLEPGK
                     TLQTPEMVWTYSSTGKGQVSRNLHDWSRNYALAHGDQELPIVLNSWEGAYFDFNEKTIT
                     DMIDDAAAFGVEMFVLDDGWFGNKYPRNSDKVGLGDWQVNRKKLPRGIDYLAKHAVSKG
                     LKFGIWIEPEMVSPKSELAEKHPEWIVKSGKRDIIPMRNQWLLDLSNPEVQDFVVKTFD
                     EVIALSPDISYIKWDANRHVDNFGSEYLSKENQTHFWIDYTKGLYSVYERIRAKHPDVL
                     IQLCSSGGGRLDFGALKYHDEFWASDNTNSLDRIFIQYSTNLFFPAKATAAHVSTTPNH
                     QTGMMAPLKFRFDVAMTGRLGMELQPEDLTGDELPFAEQAIKNYKRIRPIVQFGDLYRL
                     KSPYDGTGWASHMYISKDKKESVFFAYSLKYHGRTTFFETRLKGLDPAKMYKITELNKA
                     GNSTFYGDGQVFPGDYLMKAGISLTIGNTYESTVLLITEQ"
     CDS             14069..14731
                     /locus_tag="ctg75_13"
                     /transl_table=11
                     /translation="MKLINLNLLLLLALLVSCGESSVSSGKWTVSYDQVQKGHRIEKEN
                     QLLSDGVYASYKLGNKLVTTRDYKKSSSKVTAISDAFGQGSLLQVTYTDSNLPTLVQSF
                     YIYPEKDYLLTEFTLQGGAADVESNYMAPVTIDRMPAVLAEGDNRALFQPFDNDCWIRY
                     QSHPLTFDQLRSYEVATVFNNDDRKGFVIGSVEHSDWKTGIDMGKGDRNNIGSLVCFG"
ORIGIN
        1 ggaatatccg gcctggaact ttgttcctaa aagcaattta ctggctacag gtaacgagaa
       61 ataaggccct gccgtaaaag taaaaacacc ggtcggatcg gcatggatgc gggtgatgtc
      121 atatttggtt gaaggggttg ttcctgtata aagcgacatg tcgaatgcca tcgggcttgc
      181 cagcgctgtt atttcgccgc cgataccgaa ataaggattg aagaagtaac cgccttttac
      241 gctgacattg gttgctcccg gcgagctcag gcgtatattt ttacctacct cgatacttcc
      301 gttgatgata ctgtatccta cggcgaactc caggaaagaa gggcgccctc ctttgggggc
      361 agactccctg agcttgtcag ggagattcaa gcctttgtcc ttgaagatca ggtctgccag
      421 aaaataccct aactctgtgg ataagatgcc gataccggcc ccggccagta cgtcgctcag
      481 ccagtggcgg ttgttcagtt gccggctgaa agcggtggct gtggcgactg tatatccccc
      541 gatactatat aacgggctgc gggtcagacc atattcccgg tgcatgatgg tagcagccat
      601 gaaagcggtt gccgtgtgtc ccgaagggaa tgagttgttc tttgagccgt cggggcgttc
      661 gcgtttgatc gtatatttca tgctgttgac ggtagcggcc atgatcgttg ccgaaaaagc
      721 gttcgatacg atcatccggg gccatgaact acgactttcc acaccgccga gcttcatccc
      781 gtaaacagca agcaacggag tatattgcag aaaatcatcg tatctgtaat ggaagttggg
      841 cgtatgcgta ttgcgcaatg tccggaattt atcgccctgc ccatatgtta tggctgaaat
      901 ggcgaaaaga ggaacaggga cacgcagcat ctggtatacc ttattctctg atattttgtt
      961 gtaagtggtt tcaaattcat gttctttatt tatgaatctc gtactatctt tccactgagc
     1021 acgaacagac ggtataaaaa tcatcataaa taagaagctc agcattttac gttgtaacat
     1081 acgatcccct gattatgcca cgaagatata aaaatgccgg ttagtactgg ttacattttc
     1141 gttaatttat ttattgaata ggatttaccg tttgtccctc ctgaaatgta taggtttgat
     1201 tggcgaaata tttctttaat cgtttgcgtg atacgtgtat ttagcatacc tttgcctgat
     1261 aattgagtat attgatatga atttctaaaa acaattaaat aacttaaatt attatcttat
     1321 gtggttactt aattcttcta tcgggaagaa gctgataatg agtgtatcag gcctttttct
     1381 tgttttgttc ttattgttcc acttgtcaat gaatgtggcg gctgctttct cgggagaagc
     1441 ctataacatg atttgttcat tgttgggagc aaattggtat gccgtggcag caacattggt
     1501 gctggcagca ggcgttgtga ttcactttgt gtatgctgtt ctccttacac tgcaaaaccg
     1561 taaggctcgc ggtaacgacc gttatgcaat taacgctcgt ccgaaaggtg tggaatgggc
     1621 atctcagaac atgctggtac tgggtattat cattatcctg ttcatggtgt tgcacttcag
     1681 ccagttctgg tataagatga tgttcgccga actcctaggc aatcacatgg taacactttg
     1741 cgacggaaca acaaccgtat ctcctcagga cggtgcagcg tttatcaact actatttcca
     1801 gggtaatatc ctgaatacag tgctgtatct ggtatggtac gtagctttgt ggttccacct
     1861 gactcacggg ttctggagcg ctattcagac tatcggttgg agtaacacga tctggatgaa
     1921 ccgttggatc tgcatttcca agattgtagc aaccgttatt tgcgtagtgt ttgctatcat
     1981 tactatcgtt ttctacctga atggtgtagg tggtgactat gtagctgttt gtgcaggaca
     2041 ttaatttaag gtgtaacaat attgaaaata aatcattatg actcaaatag attctaaaat
     2101 ccctcagggc ccgttggctg agaagtggaa aaattataaa gatcatcaga aactggtgaa
     2161 ccccgcaaac aaacgtcgtc tggacgtgat tgtagttggt actggtctgg ccggtgcttc
     2221 tgctgctgcc tctctggcag aaatgggatt caacgtattg aacttctgta tccaggattc
     2281 tccccgtcgc gcacactcaa tcgccgcaca gggtggtatc aatgctgcaa agaattatca
     2341 gaatgatggt gactctgttt accgtctgtt ctacgataca atcaaaggtg gtgactatcg
     2401 tgcccgcgaa gcaaacgttt atcgtctggc tgaagtttcc aactctatta tcgaccagtg
     2461 cgtagcacag ggtgttcctt tcgctcgcga atacggtggt ttgctggata accgttcatt
     2521 cggtggtgct caggtatccc gtacgttcta tgcccgcggt cagaccggac agcagttgtt
     2581 gctgggtgct tactctgctt tgagccgtat gatcggtttg aacaaagtaa agatgtatac
     2641 ccgccacgaa atgctggacg ttgtgaaggt ggatggccgt gcccgcggta tcatcgcacg
     2701 taacctgatc acaggtcaga tcgaacgttt ttctgctcac gcagtagtgg tggcaacagg
     2761 tggttatgta aatactttct tcctgtctac taacgcaatg gcttccaacg gttctgctgc
     2821 atggcagtgc tacaagaaag gtgcttactt cgctaaccct tgtatggtgc agatccaccc
     2881 gacttgtgta ccggtgaaag gtgactacca gtctaagctg actttgatgt ctgaatcatt
     2941 gcgtaacgac ggtcgtatct gggttccgaa gaaactggaa gatgcaaaag cattacaggc
     3001 cggaactaag aaagggaaag acattcctga agcagaccgc gactactatc tggaacgccg
     3061 ttatccggca ttcggtaacc tggttccgcg tgacgtggct tcacgtgccg ctaaagaacg
     3121 ttgcgacgcc ggcttcggtg tgaacaacac aggtctggcc gtgttcctcg acttctccga
     3181 cgccatcaac cgtctgggta aagatgttgt aaaagctaaa tatggtaact tgttcgacat
     3241 gtacgaagaa attaccaacg acgatccata cgaaactccg atgatgattt atcctgcatt
     3301 gcactactcg atgggtggtc tgtgggttga ctatgaattg atgacttcta ttccgggtct
     3361 gttcgctatc ggtgaagcta acttctctga ccacggagct aaccgtctgg gtgcttctgc
     3421 gttgatgcag ggattggccg atggctactt tgtattgcct tatacaatnn nnnnnnnnat
     3481 tcagaactat ctgtcagacc agatccaggt tccacgtttc agcaccgacc tgcctgagtt
     3541 tgcagaagct gaaaagggga tcaaagaccg catcaagaaa ttgatgagta tcaagggtaa
     3601 agagtcggta gattctatcc ataagaaact gggtcatatc atgtgggaac atgtaggtat
     3661 ggcacgtgat gcaaaaggtt tgcaggaagc gatccagatg ttgaaagagc tgaagaaaga
     3721 gttctggagt aatgtatata ttccgggtga agccgataac ctgaacgtag agttggataa
     3781 ggcattgcgt ttggctgact ttattgagat tggtacattg atggcacacg atgcattgga
     3841 ccgtgccgaa tcttgtggag gacacttccg tacagagcac cagaccgagg aaggcgaagc
     3901 cctgcgtcat gacgataagt tcatgtacgt atcttgttgg gaataccagg gtgaagacaa
     3961 agatccggtt atgctgaagg aagatttgaa ctatcagttc gttgttcctc aaacacgtaa
     4021 ctacaagaag taataatcat caatcacaaa aattagaatc atggataaag atataaaagt
     4081 aacacttaaa gtttggcgtc agaaaagtcc gaaagataaa ggacaatttg agacttacca
     4141 aatagacaaa atcaatcaga gtgtttcttt cctggaaatg ttagacattt tgaatgaacg
     4201 tttggtcagt gaaggtaaag agccgatcgt attcgatcac gactgtcgtg aaggtatctg
     4261 cggtatgtgt tctttgtatg taaacggaca tccgcacgga cctgcaaccg gcgcaactac
     4321 ttgccagctt tatatgcgtc gcttcaatga tggcgaaact attacaatcg aaccgtggcg
     4381 ttctgccggt ttcccggtaa tccgcgactt gatggtagac cgttatgctt acgataaaat
     4441 tatccaggca ggtggtttcg tatcagtgaa cacaggtggt gtacctgatg ccaattcaat
     4501 cgctattcct cgtgcagatg ctgaaatggc tatggatgct gctgcatgta tcggttgcgg
     4561 tgcttgtgct gctgcttgta agaacggttc ggctatgttg ttcgtttctg caaaggttag
     4621 ccagttggct ctgttgcctc agggtaaggt agaagctgct cgtcgtgcga aagcaatggt
     4681 tgccaagatg gacgaactgg gcttcggtaa ctgtaccaac acgcgtgctt gcgaaatgga
     4741 atgtccgaag aacatctctg tcagcaacat cgctcgtttg aaccgcgagt tcatttgtgc
     4801 taaattgcaa gactaatata cattatatat gtatgtccgg agaggcgttg cttatggcag
     4861 cgcctcttct tttttgcccc tattttaaca tttctgaagt catagataaa tatcttgaat
     4921 gttgttagtg tttcttatat gctatacaac actaattagc attttaacta ttgacaagtt
     4981 ggagaatacc tgtatctttg tactgtggtt ttttcataat agtattagat ttaaggttaa
     5041 caaagttggt tagggcttgt cgtgagacag gctttaattg tttatagggg tttgcgtccg
     5101 gcatatccct ttttttagct ctccctgtat tcctgcgggg tcattcctac atgttgccgg
     5161 aaatatttgt tgaagaacga aaggttgtcg aaacccaggg cgaatgcaat tttcttgacc
     5221 ggcatatcgg tcgatttaag ctgcgctttg gcatccataa tgatgatatt gctcaggata
     5281 tccaatgcag tccgtccgct gacctttttt atcacataac agaaatgctg caaggtgatg
     5341 ttgagccttt tggcgtaata agacacgcta tgctctttcg tgtagttttc catcgccagt
     5401 tgtacgaact cccggcatat ttccatgtta cgcgtcatgg gagcattgct atatggcgta
     5461 tgattcctgt ataattcaat aaccccttgc atgaagatag taaagattgc cttgataatc
     5521 tccttgttct cgatggtttt aggcatggaa taagcattga tcagcaagtc gaaagcctgt
     5581 tggtagagta aggatatatg ttccggcaga ggcatgatcg gactgtcgaa tatgacaggc
     5641 agatagttcg taatcgtctt tatataattg atatggctga cgaatacgga agaaaagcct
     5701 gcaaaacaca gttttacatc atcggaaacc tcatgtatct gaatgaagca acccgggggt
     5761 aaggtgataa agtcgttctt ccggatggta aactcagtta agtttacagt cgcgtggact
     5821 gtcccttgta cgcaaagcac gaatatgcca gccttgatct tgcacgggaa acgtccgtac
     5881 tggttcagta tttcacctgt aatactgttt cctacaataa aatctacggg gaggtcgaat
     5941 ttaggaatat tgtcttccat acttttatat acacttaatt gaatgtacaa agatagtttt
     6001 tttgagacaa gttagtcgat aatcttaaat atagaacatc gaatcccaca aatggagatt
     6061 gttttgtgct gtataatagt tgaaatttgc gaatgttttc aagtcttgct gatagatttg
     6121 ttgggatggt atatatttgt ctatctgcta aataagatat gggagctaat actaatagag
     6181 aaatctaatc gataataaca atgagtacga aaagaacaaa gagctctttc aggacaatga
     6241 gcacaaacag aaaattagaa tctgttttcc tgtttgtcac aggacggtgt aatgctaaat
     6301 gtaaaatgtg tttctatgca gaagacatgg ataaaaagga gaaagacctg acttttgaag
     6361 aaatcaagac aatctccgaa acagccgggc agttcaaccg tttgtgggta tccggcggtg
     6421 aaccgacact gcgtgaggag ttacctgaaa ttatagagat gttctacaag aataacgaga
     6481 taaaggacgt gaatatccct accaacggat tgaagcctga ccggatcgtc gcctgggtaa
     6541 aacagatccg ccagaattgt ccggaactga atatcaacct gagcctttct ttggacggtt
     6601 tcggtgatac gcatgatata cagcgcggcg ttcccggcaa tttctacaaa gcgatgggga
     6661 cactgaagct gattgaaaaa aactttgctg acgacggcag ggtgttgaaa aacctggcca
     6721 ccgtaatcac caaatataac gagaatgagg tcgaggatct gatgatatgg atgctgggac
     6781 gtttccatct ttccaatcat attattgaag ctgcacgcgg tatgacccgc gacgacggag
     6841 tgaaggttct taccgagcct actctacgcg ccttgcagga taaggttgtt cctatttata
     6901 atgtatatgg ggagcgtatg gcggaggaaa ccggtgggtt cagaaaacct atcgcccgtt
     6961 tcttctacct gggtttcata cgtacattat ataatgtacg tgcgaccaat atcgatcatc
     7021 cgacaccctg gggtatggat tgtacggccg gcgaaacaac actggtaata gactatgacg
     7081 gtcgtttccg tgcctgtgaa cttcgcgaac cgctcggtaa tgtcaaggat tatgactgca
     7141 atatcgcaaa gattatggag agcgatgcca tgaaacaaga gattgccgct atcggtcatg
     7201 gtgacaaggc taactgctgg tgtacgcatg ggtgttggat cacttcatcg cttgttttca
     7261 atccccgcaa gatgatcacg caggtctata aaggataccg ggagatgaag aagctgaacc
     7321 gtcctctgaa tatcagtgaa gagcttttgc agagtatcga acgcaaatat gccttggacg
     7381 aacagaaact ggtggagctg ggagttcgta attaaaatag ttccgataac ggatcattta
     7441 taaagccggt tgacgggaaa tatacctctg ttaaccggct ttattgtgtt taagggaata
     7501 attgtcaaat tatccggtag aattgccatt tcccataggg gaaaaatgtc ggatctttgc
     7561 atcataagtt aaactgataa acaaagaaag acatgactac taaattaaaa gatttattcg
     7621 acacatttct gaacattgca gcttcttcac agaaactggg tattaacctg atccgcgtag
     7681 ctatcctgat tatattcgta tggatcggcg ggctgaaatt ctataattat gaagcggaag
     7741 ggatcgttcc ttttgtggca aacagtccgt ttatgagctt tttctatgca aagagtgcac
     7801 cggaatacaa agaatataag ttgaaagaag gtgaattcaa tgaagccaag catcagtggc
     7861 atgtagaaaa caatacctat attttttcac atggactagg cattatgatc atggcgatcg
     7921 gtatcctgac tttcctgggt atcttttctc cgaaaattgg cttgataggt tccggactgg
     7981 cgatcataat gacattgggt acgctttcat tcctggtgac aacacctgaa gtgtgggtgc
     8041 ccgatttggg aagcggagaa catggtttcc ccttactgac cggagcaggt cggctggtaa
     8101 taaaagatac ggcaatcata gccggagcga tcgtggtatt gtccgactgt gcacaacgta
     8161 tattaaagaa gaaataggaa taaaaagtgt ttattttaac actttggaag caaaaaacaa
     8221 acatattgaa ccttgttagc ttttcttata gtgtatgaaa caccatttag cataaaacct
     8281 cttgacaggt ttggattaag cagtatattt gcatcgtggt tttttcataa tagtattaga
     8341 tttaaggtta acaaagttgg ttagggcttg tcgtgagaca ggctttaatt gtttataggg
     8401 gtttgcattc ggaaatgcaa gccttttttc ttttaaatac ggcattctct gaaaaataac
     8461 tccctttttt atcggtaata ttcggcaatt caccgatatt tgactgtaat aggacgtatt
     8521 tctattgccg gaaggctgac aggagcatac ttttgctctc aaacaattaa actgtatatc
     8581 gtatgaatct taggaaaaac ttattttggg ccatcccgtt tattgtagtg ggggtcgtat
     8641 ggatcatgag gaacacaggc atgatcacgg atgatctttt tcatatcatt gtatcctggc
     8701 agatgcttgt aatgtatata ggtataggga gtatttcccg gagacattat ataggcggtt
     8761 tgattacctt tttggttggt gcggcatttt tactgccacg actggggtgg atggatagcg
     8821 attggttgca ggtctattgg ccggctgctt ttgtcattgt cggtttaatg ctgatcttcg
     8881 aaccgcgtaa aaagaactcc tatcattaca atagccggag agaggatacc ggtggagaag
     8941 atatccgggg aaatgccgtt gccggtaaag taaaaagtga ttttattaat acggacggat
     9001 atgtggaatc ggataataca tttggctatg tggaacaaat tattttagat ccggtattta
     9061 aaggagccag gattaggact gtgtttgggg gaacggtcct ggatttgcgg aaaacgaagc
     9121 tggatagtgc taaaacctat attgatatcg attgtaagtt tgccggtgtg gaaatctatc
     9181 ttcctgggga ttgggcggtc aattttcatg gcagtccgat catgggggca tgcgaggata
     9241 aacgttttaa tgcctctatg gaaatggata aagaacatat actggttgta cggggaattg
     9301 ttatgttcgg tggcattgaa tttaagagtt gattatgcag acacatccgt ttataaattc
     9361 tgtcctgtgt agaatggctg gtgtggcttt ggctgtggtc agttgcagca taagcgcctt
     9421 gctcctctat tattacggac atacgggatg gcttgtcgca tggttggata gtctggtttc
     9481 ggtcggtata ttctgtgtct ccggtttcct gttctggtat gtaacaggca tattgcggcc
     9541 attacaggcc cagattgcat tggctgttgg cgtccttatc atatccgtta ccggaggata
     9601 tatggccggg gcgctggttt atccggatag gatggattgg tttgcatcta ccattccgtt
     9661 ccgtattttg ttgggtttgc tgggatggat tattttggcc cagtggtatt atatccgttg
     9721 gaaggagttg cagatggaga tacaggagga acagagaaaa gaagaaaatg ctccggcgga
     9781 aacaggcgta tcgtcaccgg aagaggaagc aatactggat cgcatctctg tgaaggatgg
     9841 cagccgtatc catctgatcc acctggagga gttactttat atccaggcca gcggtgacta
     9901 tgtggcactc ttcacgaccg acggacagta tataaaagat cagacaatga aatattttga
     9961 atcgcatctg ccggcaaacc tgtttatccg tattcaccgt tcctgtatcg ttaatagcga
    10021 acagatcatg cgtgtggaac tgttcggcaa ggaaagttac caggttcgtc ttaaaacagg
    10081 tgtctgtctg cgtgccagcc tgaccggata caagttgctt aaagaacgtc tttctctata
    10141 gatttggctg ttttaactgt taaaattagc agtttttgtc tgtattgtat aaagttttgt
    10201 gttcggaaac aatttttagc tacaatgccc gaaaggctta acatatattg tctgtaaaag
    10261 acttgacaaa cgcttgtttc aggcttatct ttgtactgtg gttttttcat aatagtatta
    10321 gatttaaggt taacaaagtt ggttagggct tgtcgtgaga caggctttaa ttgtttatag
    10381 ggggttcttt tctcatcatt ttgtatgaat ctttgatttt gaggtgttat ctttgcaagc
    10441 tatggaatat ataggactgc atgaagataa aatatcactt gctgatatta taaaatatct
    10501 ttctcttttg aaaggtaata tggatgaatt gaatttgctt gaattcaaaa ccattaaagg
    10561 ttggttggtt tattctttgt cattagttct tttgttgtgt ataccttgtg taatcatttt
    10621 attaataaca ggtcttttat ccggaaatat agatagcgga ttattattgg ctgtttcttt
    10681 tatccctttc ctctttattt tgcctttgac attgttattg actttcatca acaattacag
    10741 aaaacccaaa aagttgaggg aactaatgca gacggttttg atgcgttacg aatgggatgg
    10801 tcctatcaat caaaccggac ggttgcagtt ggaatgcagg aaggaccatt ttctgtttag
    10861 aacggaagtt ttgcggcaaa tgaatcccaa agggcgtaat gtgtctttga ttttcatatc
    10921 cgttcctttc tatgtaccga tagaaaagga gctgatacat gccgaagata taattgctta
    10981 tctgaaaggc aagtctcttt tcgtgattga gccagatatg gcatgtttgg gaatgtcgtt
    11041 taaaatgttt cagaaactgg atttgcgtga agatattgat cagttgattt atgtgatgaa
    11101 acgtttttcc cttcgccccg gaacactctt caaggcgcag gatataactt tgaaagttcc
    11161 tgaaacactg gaaatacagg cactgtttat tttcggtcaa aaaatagacc aaaggtttct
    11221 gaattgggct aacctgatgc ttgatgccgg atttgtgagt gataatatga aaattatggc
    11281 tgaacaagca tctctgactc tccctcaaaa agaattgaag aaaagagtgg aggtgatttt
    11341 cctggagttt aatttgtatt tctctaaaga gactgtatta aataattatt tgatattcct
    11401 tatactggaa gaacaggaag aacgaaggtc tgttttggag attatacaat gtctggccag
    11461 tctctatcaa tcttccaggc tgcctctgtt gcaagaatat gatctgttat ataaagctaa
    11521 aagggcattg gatgaaacag gagaacaaaa tttctggacg gcagacccgc ctttgacggt
    11581 cgataatgtg gatacttata tattaaccta tttgaccaga aggctagctg acctgatagc
    11641 ctctcgagaa aaggatcagt gatcgatcat ccctttgtaa cagatgcgtc aaaaaatgac
    11701 gtaaatgttg catttttatt aaacctctat gaattaagcg cataattaca aataattggc
    11761 gagttcgtgc tttttgtgct attgtttatt gatttagttt gcaccatcaa ccttgaataa
    11821 gtaaaataaa tttgatagac atgaaagcac tattgttaac tgttgccctg ctgctggggt
    11881 gcgtaaccgt ttcctcacag gataaagata cggggataat taccgtctct acaaacgatc
    11941 tgagtatggt cttttcgatc tctccggata agaaagtagt gtataactat tttggcgata
    12001 aattccagga cgtttcccct ttccttcata agaagtataa agaacaaccg gataacggaa
    12061 tcggttatgc tccggtaatc tatccggctt acggaggacg tttcttcctg aatccggcat
    12121 tgaaactgac ccatgacgac ggcgttcaga caaccgaatt aatatatgca gctcatcagg
    12181 taaagaatat agataataat agaatagaaa cagtgataca attgaaagat cctttgtatc
    12241 cggttttcgt taacctgaac ttcacggctt atcagaaaga aaatgtaatc tgccagtcag
    12301 tctccatatc ccatcaggag aaaaacaagc tggctgtcga gaatattgcc tccgcttatc
    12361 ttccccttca tgcagattct tattatctga cccatttcca cggggcctgg gcttccgaaa
    12421 tgcaactggt agaagaacaa ctgacaccgg gtgtgaaacg ggtggaatcc aagaagggga
    12481 tacgtactac ccagtctgaa aactcttctt tcctgctttc cctgaatggc cctgccaatg
    12541 aagacatggg cgaagtgtat gccggctccc tggcctggtt aggtaactat ctgtcttcct
    12601 ttgagataga cgaatgcggt ttgctgcatg tcatgagcgg gatgaatgat tttgcctcta
    12661 cttataatct ggaaccgggt aaaacgttgc agactccgga aatggtctgg acatacagtt
    12721 ctaccggtaa gggacaggta tcgagaaacc tccatgactg gtcgcgtaac tatgcattgg
    12781 cccatggaga tcaggaattg cctatcgtcc tgaatagctg ggaaggcgct tatttcgatt
    12841 ttaatgaaaa aacgattacg gatatgatcg atgacgctgc tgcttttggc gttgaaatgt
    12901 tcgtactcga tgacggatgg ttcggaaata aatatccccg caattcggat aaggttggtt
    12961 tgggcgattg gcaggtgaac aggaaaaaac tgccacgcgg aatcgattat ctggcgaagc
    13021 atgcggtaag taaaggattg aagttcggta tctggattga gcctgaaatg gtaagtccca
    13081 agagtgaact ggcagagaag catccggaat ggatcgtcaa gagcggtaaa cgtgatataa
    13141 tcccgatgcg taaccagtgg ttactcgatt tgagtaatcc ggaggtacag gactttgttg
    13201 taaagacgtt tgatgaagtg atcgctttgt ctcctgatat ctcttatata aaatgggatg
    13261 caaaccgtca cgtggataat ttcggttccg aatatctgtc caaagaaaat cagactcatt
    13321 tctggattga ctatacaaag ggcttgtaca gtgtttacga acggattcgt gcaaaacacc
    13381 cggatgttct tattcagttg tgttcttcgg gtggcggccg tctcgacttc ggtgcattga
    13441 aatatcatga cgagttctgg gctagcgata acaccaattc gcttgaccgt atattcatcc
    13501 aatacagcac aaatcttttc ttcccggcaa aggctacggc cgcccatgtt tcgactactc
    13561 cgaatcatca gacgggtatg atggcgccgc tgaagttccg ttttgatgtg gctatgacag
    13621 gccgcctggg catggagctg caacccgaag acttgaccgg cgacgaacta cctttcgctg
    13681 agcaagctat aaagaattat aaacgtatcc gcccgatcgt acagtttgga gacctctatc
    13741 gcctgaaatc tccttacgac ggaaccggct gggcttcaca tatgtatata tctaaggata
    13801 aaaaggaatc ggtgtttttt gcttatagcc tgaaatacca cggacgtaca acattctttg
    13861 agaccagatt gaaaggactg gacccagcta aaatgtataa gatcacagag ttgaacaaag
    13921 ccgggaacag caccttctat ggcgacggtc aggttttccc cggtgattat ctgatgaaag
    13981 ccggaatcag cctgacgata gggaatactt atgaaagtac cgttctgttg ataacggaac
    14041 aatgaaacta tctataaatt atcaatacat gaaactcatc aatttaaatc tgctgctatt
    14101 gctcgccctg cttgtatcct gcggcgaatc atccgtttct tcgggaaagt ggacggttag
    14161 ctatgaccag gtgcagaaag gccaccgtat cgagaaggag aaccagcttc tttccgatgg
    14221 ggtttatgcc tcctacaagt tgggtaataa gttggtcacg acccgtgact acaaaaagag
    14281 cagttcgaaa gtcaccgcta tcagcgatgc tttcggtcag ggttcattgt tgcaggtgac
    14341 ctacacggat agcaacctgc ctacgcttgt acaatctttc tacatctatc cggagaaaga
    14401 ttatctgctg acggaattta ctcttcaggg aggagccgct gacgttgaat cgaattatat
    14461 ggccccggtt actatcgacc gcatgccggc cgtgttggct gaaggtgata accgcgcgtt
    14521 attccagcct ttcgataacg attgctggat acgttatcag tctcatccgc tcactttcga
    14581 tcaattacgt agctatgaag tagcgactgt cttcaacaac gacgaccgta aaggttttgt
    14641 catcggttca gtggaacact ccgactggaa gaccggtatc gatatgggga aaggcgaccg
    14701 taataatatc ggttcattgg tttgcttcgg cgg
//
