LOCUS       c00008_gnlPro..        14242 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PAGLIMPC_8.
ACCESSION   c00008_gnlPro..
VERSION     c00008_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 11:57:33
            Original ID  :: gnl|Prokka|PAGLIMPC_8
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14242
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..117)
                     /locus_tag="ctg8_1"
                     /transl_table=11
                     /translation="MKNWSKSRIWSLKIPKNRSDRNLNVTTDGERMDNRVVCE"
     protocluster    1..14242
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[6668:10247](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(6669..10247)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..14242
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14242
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(59..214)
                     /locus_tag="ctg8_2"
                     /transl_table=11
                     /translation="MRYTVIGLGQFGQELCTELSARNIEVVAVASTDEELEQIKDLVLE
                     NSKEPF"
     CDS             complement(225..1973)
                     /locus_tag="ctg8_3"
                     /transl_table=11
                     /translation="MTTTRSGFTKLAAVCIAILLGAVVWELGWPLTRAEHEWSRLIAAV
                     ATLGHLTGILGSYFRKEINRPSLRLLIFQIISCLMIFLLIAREQQEAGYMRFTELSRLV
                     ITAGLIAIPTLMSLTRIFEWLVGKQKKGRPLMAPAMQFVASLGVVILAGTGLLLLPNST
                     YPGITLSFTDALFTSTSAVCVTGLNAVDFAHTFTPLGEMFTLALIQIGGFGIMTFAYFV
                     AMVAGQGFSLRDRVLLTDLLDEDNLGAVVSFITTIVVSTLFIELCGAVLLYFSWEGKDI
                     NLMGEPLWWHSLFHSVSAFCNAGFSTFPMNLMEPGIRLCYSGQAVIMALIVCGGLGFGI
                     YKEINSRLANRFFSKHRRLHMQWTPYFKLVMISTGILLAGGALAIFAVSSPHAAEPLGE
                     HLWICLFDSVTARTAGFNISDYGRYLPAASLIMCGLMMVGGSPGGTAGGMRTTTCAIAG
                     AEILRILRGRDHVEFFRRRIDQRTVARCVITVVVSCAWIGCFTVLICALEPSMSSLDIF
                     FENCSAFATVGVSRGITPDLSGPSKYLLIVNMLAGRVGLFAFLIALAGTPTPRHYRYPS
                     VKIPLT"
     CDS             2286..3053
                     /locus_tag="ctg8_4"
                     /transl_table=11
                     /translation="VLAKRIIPCLDVTDGRVVKGTNFINLRDAGDPVECARAYDAQQAD
                     ELVFLDITASSDGRATMADVVRRTAACCFMPLTVGGGIRSVKDMREMLLAGADKVSLNT
                     AAINRPELINEGAAAFGSQCIVVAIDAKRQASGKWGVSTHGGRKFVGLDAVEWAVEAER
                     RGAGEILLTSMDADGAKTGYDIELTRAVSSAVRIPVIASGGAGNLDHMVDVLVEGKADA
                     VLAASIFHFGEYTVPEAKAYFASRGIPVRPLAE"
     CDS             3101..5239
                     /locus_tag="ctg8_5"
                     /transl_table=11
                     /translation="MRMRCLFFPLCSAIALTSFVQAQSLERHPLYEPALVSAGTPGDAG
                     NLFAGAKVTASGHYGSDRPELAVDGQTNNAGKYWGCEGIPVWLQIDMGKPRTLSSLHVW
                     PYWEGGRIYKYKIEGSEDGKNWKMLADQSSNSIAATPEGVPFKFNPQTVRYVKITFLGN
                     SAGNEKGGHLVEIKGYGPDAALSLQAAAVKDYDRIPYNGAPGQEMLQDAVRLSGWRGER
                     AGGQIAVWSSQAQPQLSASCAGVKNAAGQIIPVRTAMIRYTRGGNRLISDIIGSENSCD
                     LQAGGVRPVWVEVNIPPSAKPGVYKGKVVISAESGSPVSVPVILEVAPESLPAPAHWQV
                     HLDLWQHPQAVARWHDVEPWSPEHFALMKPVMKRLADAGQKAITCSLIDEAWNAQTYDW
                     FPPMIEWVKGKNGTMRWNYANFDKWVSFMMNEVGVKGQISCYTMIPWNMKIRYLDEATG
                     KYKFLDLKPNDPSYEAIWGPFLTDFRKHVKSKGWLGKTCIGLDERPDAMVRAAKNVLDK
                     YAPEFKIVSAVNRPTAMTRDVYDVSPVIDHAGTVTGDLLAQRKKEGKKTTFYVCVHPKK
                     PNTFTMSPLAEAEWLPLFAAANHLDGFLRWAYNSWNRNPFEKTDFGNWPAGDCYLVYPG
                     NLSSLRFEKLRDGLEEFEKVNILRARAAKNPKAKAAVARMDEELSKLFTVEKSRGDSHE
                     EDVRKAREIIRKTTEISR"
     CDS             complement(5321..5641)
                     /locus_tag="ctg8_6"
                     /transl_table=11
                     /translation="MTYYNSSCPVETTLQLISSRWKVLILRDLLEGTRRFGELRKSIGP
                     VTQKVLTANLRSMEKDGLLTRKVYAEVPPRVEYTLTELGRSLRPVLASMAEWGSKYQRE
                     NR"
     CDS             5766..6203
                     /locus_tag="ctg8_7"
                     /transl_table=11
                     /translation="MNKIIIANYRETEPQVISREGNSFAVKPVIREADAGKCAASFVEV
                     EPGRYAYGYHYHEVNEEVFYIIRGHAVVRTPEGEKNLKEGDAIAFPASPEGAHVIRNGS
                     ATEKLVYLDVGTRLTPDVVHFPDTASGMVYSSSGVHHFRES"
     CDS             complement(6669..10247)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_8"
                     /sec_met_domain="PFOR_II (E-value: 4e-18, bitscore: 55.4,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 3e-79, bitscore: 255.6,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 1.1e-32, bitscore: 103.1,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.3e-12, bitscore:
                     36.1, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 7.2e-14, bitscore: 42.3,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 7.7e-11, bitscore: 31.5,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.5e-06, bitscore: 17.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 2e-26, bitscore: 81.3,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDQTTVTYSTIDANEAVASVAYRFSEVIAIYPITPSSPMGESAE
                     SWAAVNRKNLWGTVPSVVEMQSEGGAAGTVHGALQTGALATTFTASQGLLLMIPNMFKI
                     AGELTPAVFHVAARSLAYQALSIFGDHSDVMSARSCGWAMLCGSSTQEAADFAAISHAA
                     TLESRIPFINFFDGFRTSHEIGKIADITDDTLNGMIKQEWLDSFRERALTPDAPVLRGT
                     AQNPDVYFQGRETVNRFYEATPAIVQNAMDKFAELTGRSYHLVDYTGAPDAERVIILMG
                     SGAEAVEETVEAMMTRENAKVGVLKVRLFRPFPAAELVKALPATVRKIAVLDRTKEPGS
                     QGEPLHQDIIQALFDAQANGTLPFTNGMPKVVGGRYGLSSKEFTPAMVKGVYDNLALDT
                     PKNHFTIGINDDVLGTSLPYDEDYSTEADDVTRAMFFGLGSDGTVGANKDAIKIIGQHT
                     NLYVQGYFVYDSKKSGSSTISHLRFGPRPIKSTYLITKANFLALHQPSLLDLFDFLKNA
                     ANGATFLMNSPHPADKLWDTLPARMQQQILDKNIKLYTIDAFAVARKTGMGGRINMIMQ
                     TCFFKLASVIPADEAIGYIKKAIAKTYAKKGQEVVDKNIAAVDATLENLHQVDTTGKTV
                     NGHAIPPAMSPDAPDYVQNVLGKMMCGEGDSIPVSQMPVDGTFPNGTSQYEKRNLALDL
                     PEWDPTLCIQCGKCTAVCPHAVIRSKFFSPDALANAPEGFECLDAKHPDWKGEKFVIQI
                     SPNDCTGCTLCADVCPAKSKTDPTYKALTMVPAGKIHDKEEANWNFFLSLPDVDRTKVR
                     TDNIRSMQVLRPLFEFSGACAGCGETPYVKMLSQLFGNRLVVANATGCSSIYGGNLPTT
                     PWSHDSEGRGPAWANSLFEDNAEFGLGFRVSLDKQMEHAIELLHEAAGAVGQELVDRIL
                     ANPQKDEADIAQQRENIEELKKKIAGKPEYARLLTLADKLVRKSVWILGGDGWAYDIGY
                     GGLDHILASGRNVKVLVMDTEVYSNTGGQCSKSTPRAAVAKFATNGKPGVKKDLGLMAM
                     TYGNVYVASVALGAKDEHTLKAFVEAEAYDGPALIIAYSHCISHGINMAKGLQQQKAWV
                     DSGRVLLYRYNPDLARQGKNPLIVEGKGPKGDLRDVLLSENRFKLLAKTNKEGFEKLLE
                     EAQKDVWHRWNLYQSIAGMGADKPAE"
     CDS             10594..12075
                     /locus_tag="ctg8_9"
                     /transl_table=11
                     /translation="MSEQQQAHPTTTESELIAVRRDKLAKIRELGIDPYGARFDVTTTP
                     AGLKADFQEDKQVAVAGRLLAIRDMGKSQFFVIGDVRGKIQGFLHKNEVDETTWKLWKL
                     LDRGDWVGIRGTTFLTRTGEPTVKVSGLTILSKSLRPLPDKWHGLADKEVTYRKRHLDL
                     ISNEESASLFVTRSLMIAEIRRFLQERGYLEVETPMLQDVAGGAAAKPFETYHNALDMP
                     LTLRIAPELFLKRLMVGGFTKIFELNRSFRNEGIDRRHNPEFTMLEAYCACGDFETMAN
                     MVEELICHLAEKFCGGLQIDHKDAEGNVLYTIDLSRPWRRADYQDLIRGVAGEDWFDIS
                     PEARRARCEELGVEISPDMKDVDVSQQVYEKLVEEKTMNPCFVTHVAKDLVPLAKLNRE
                     NPDVVDVYELVINGQEISPGYSELNDPDVQKERLEHQAAGETQRVDYDFIETLEYGMPS
                     AGGIGIGIDRVVMMLTGASSIRDVLLFPQLKRKDS"
     CDS             12093..12878
                     /locus_tag="ctg8_10"
                     /transl_table=11
                     /translation="MVPRTPDILDCASAQWIGKRREQEDVVKSLPAAGGMLGIVCDGMG
                     GHLRGDCASCVVAQEFAAVFAESGIEDIPERLTAALHAANRALSAIQKEPEESGTTLLA
                     VFIRDHFLWWISVGDSPLYLWSGADSFRMDRLNEDHSMRPIADSLYRKGKMSLQGALRQ
                     RCILRSAVMGGPMELVDISAMPLLLHPGDAVLACSDGLQVWSELLREPSFLALQKARDC
                     SSRELVGIIMEQVKDMLEPQQDNASVWAAVMRKPCEGGK"
     CDS             13131..13775
                     /locus_tag="ctg8_11"
                     /transl_table=11
                     /translation="MIAWIVFYYLIGAIPFGYLAGRIRGIDLRQQGSRNIGATNAWRVL
                     GWKWGLSVFILDFLKGFIPVFGALNWLPFLTGDAGGWDFNVLVVLSCFAVILGHTYTCF
                     LGFRGGKGVATTAGVLFALNPVVACVALASWLVVMGISGIVSLASLVAAVVMIAAGWWI
                     YPLCQDGDVSPQILYVAFFTVVGALVILKHRSNIARLLNGTEHSFYSKKSK"
     CDS             13780..14241
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_Gly3P_dh_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_12"
                     /sec_met_domain="NAD_Gly3P_dh_N (E-value: 6.3e-43,
                     bitscore: 136.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNRLHKIAVIGAGSWGTALSMVLATRECEVVLWTPEEAQARQLAE
                     TRRSPVLSKTALPLAPNIHPTCDLGQVKDAELIVVVVPSVAMRSVAQRLRSLPVQPDAV
                     IVSCTKGIEQGTHKRMTEILQEYLPSNPIGVLSGPNHAEDICLGLPSASL"
ORIGIN
        1 ctcacacacc acacggttgt ccatacgctc gccatcggtg gtgacgttga gattcctatc
       61 agaacggttc tttggaattt tcaaggacca gatccttgat ttgctccaat tcttcatccg
      121 tggaggcaac ggctactact tcaatattac gggcggaaag ttctgtgcag agttcctgcc
      181 caaactggcc caggccgata acggtgtatc tcataatggt atattcaggt taacgggatt
      241 ttgacggatg gatagcggta atgcctcgga gtaggggtgc cggccagcgc aatgagaaaa
      301 gcgaagagcc ccacgcggcc ggcgagcatg ttgacgataa gaaggtattt ggaagggccg
      361 cttaaatctg gagtaatgcc ccgcgacacg cctaccgtag caaaagcgct gcagttttca
      421 aagaagatat ccagagagct catggagggc tccagggcgc aaatcaggac ggtaaagcag
      481 ccgatccagg cgcaggagac caccacggta atcacgcagc gcgccacggt gcgctggtcg
      541 atgcggcggc ggaagaattc cacatgatcc ctgccgcgga ggatgcgcag gatttccgcg
      601 cctgcaatgg cgcaggtagt ggttctcatg ccgcctgccg tgccgccggg gctgcctccc
      661 accatcatca gaccgcacat aatgaggctg gctgcgggca gatagcggcc gtagtcgctg
      721 atattgaatc ccgccgtgcg tgccgtgacg ctgtcgaaaa ggcaaatcca gaggtgttcc
      781 cccaacggtt ccgcggcatg gggagaggaa acggcaaaga tggccagggc gcctcccgcc
      841 agcaaaatcc ccgtggagat catcaccagt ttgaagtaag gggtccactg catgtgcagg
      901 cggcggtgtt tggaaaaaaa gcggtttgcc aggcgtgaat taatttcctt gtaaatgccg
      961 aatcccaggc cgccgcatac gatcagcgcc atgatgaccg cctgcccgct gtagcacagg
     1021 cggatgcccg gctccatcaa attcatcggg aaagttgaaa aaccagcatt gcagaaggcg
     1081 gaaacggagt ggaacaggga atgccaccac aaaggctccc ccatcaggtt gatgtccttc
     1141 ccttcccagg agaaataaag aaggacggcg ccgcacagtt cgatgaacag cgtactgacc
     1201 acaatagtgg tgataaagga gacgacggct cccagattgt cttcatcaag cagatccgtc
     1261 agcagcacgc ggtccctcag ggaaaaaccc tggcctgcca ccatggctac gaagtaggcg
     1321 aacgtcatga tgccgaatcc gccaatctgg ataagggcaa gcgtgaacat ttctcccagc
     1381 ggggtaaaag tatgggcaaa atccacggcg ttcagaccgg tgacgcatac tgcgctggtg
     1441 ctggtgaaca gggcatccgt aaaactgagt gtaatacccg gatatgtgga attaggcagc
     1501 agaagcaatc cggtgcctgc caggatgact actcccagag aagctacaaa ctgcatggcg
     1561 ggggccataa gaggccggcc ttttttttgc ttgcccacca gccattcaaa aatcctggtc
     1621 agggacatca gcgtggggat ggcaatcagc ccggccgtaa tcaccaggcg ggaaagctcc
     1681 gtgaacctca tgtatcccgc ttcctgttgt tccctggcaa tcaggagaaa aatcatgagg
     1741 cagctgatga tttggaaaat caggagcctc agggaagggc ggttgatttc cttccggaaa
     1801 taggaaccca gaatacccgt caggtggccc agcgtggcaa cggctgcaat cagccgcgac
     1861 cactcatgtt ccgcccgcgt caggggccag cccagctccc agaccaccgc ccccagaaga
     1921 atggcaatgc agacggctgc aagtttggtg aatcccgagc gtgtagtggt catgaatgga
     1981 aatgccttat gcggactcta ccacctggac atggaaagaa aagctcttag gccgttttat
     2041 gcatgcgggc gggaaagggg cagatgccgc actgcgtttc ttcatggcgg ggcagggccg
     2101 gccggaaagt gagtggaata gtgatattga tgaatttcag taaatttctc ttaccgggat
     2161 atgcgggatg gaaacgctgc cgaagagggc cttggtcaaa aagggaacat gtttatcaaa
     2221 aggcatcccg cggcaagccg tattttaggc ttttcctttg gcggcggtga tggcttgata
     2281 gggccgtgct ggctaaaaga atcattccgt gtctggacgt aacggacggc agggtcgtca
     2341 aggggaccaa tttcattaat ttgagagatg ccggggatcc tgtagaatgt gccagggcgt
     2401 atgatgccca gcaggcggat gaacttgttt ttctggatat taccgcttct tccgatggcc
     2461 gtgccaccat ggcggacgtg gtgcgccgca cggcggcatg ctgcttcatg ccgctgacgg
     2521 taggcggcgg catccgttcc gtaaaggaca tgcgcgaaat gcttctggcg ggtgcggaca
     2581 aggtttccct gaatacggcg gccatcaata ggccggagct gattaatgaa ggtgcggcgg
     2641 cttttggcag ccagtgcatc gtcgtcgcta ttgacgccaa gcgccaggct tccggcaagt
     2701 ggggcgtttc cacccatgga ggccggaaat tcgtggggct ggatgccgtg gaatgggctg
     2761 tggaggcgga acgccgcgga gccggggaaa tcttgttgac cagcatggat gcggacggag
     2821 ccaaaacggg ttatgatatt gaattgaccc gcgccgtaag cagtgcggtg cgcattccgg
     2881 taatcgccag cgggggtgcg ggtaatttgg atcacatggt ggacgtgctg gtggaaggga
     2941 aggcggatgc cgtgctggcg gcttccattt tccattttgg ggaatacacg gtgccggaag
     3001 ccaaggctta ctttgcttcc agaggaatac ccgtgcgtcc tttggcggaa tagcggaaac
     3061 agcttttctt ttgagagaaa atgaaattcc ggcgcgtaat atgcgtatgc gctgtctttt
     3121 ttttcctctg tgttccgcta ttgccttaac gtcttttgtc caggcccagt ccctggagag
     3181 gcatcccctg tatgaacccg cccttgtttc cgcaggaact ccgggtgatg caggtaattt
     3241 atttgccgga gccaaagtaa ctgcttccgg tcattacggc agtgaccgtc cggaactggc
     3301 cgtggacggg cagacgaata acgccggcaa atactggggt tgcgagggca ttcccgtctg
     3361 gctccagata gatatgggaa agccccggac gctttcctct ctgcatgtat ggccctattg
     3421 ggagggaggg cgcatttaca aatataaaat agaaggttcc gaagacggaa agaactggaa
     3481 aatgttggcg gatcagtctt ccaacagcat tgccgccact ccggaaggcg ttcccttcaa
     3541 attcaatccg cagacggtcc gttacgttaa aatcactttt ttgggcaata gcgccggcaa
     3601 tgagaagggg gggcatctgg tggaaatcaa agggtacgga cccgatgccg ccctgagcct
     3661 gcaggctgca gcggtgaagg attatgaccg tattccttac aatggcgctc ccgggcagga
     3721 aatgcttcag gatgccgtgc gtctgtccgg ctggagaggc gaacgcgccg gcgggcagat
     3781 tgccgtctgg tcttcccagg cgcagcccca gttatcggcc tcctgcgccg gggtaaaaaa
     3841 cgctgccgga cagattatcc ctgtccggac tgccatgata cgctacacca gggggggcaa
     3901 caggctgatt tcagatatca tcggcagcga aaacagctgc gatttgcaag ccggaggcgt
     3961 gcgtccggta tgggtggagg tcaatatccc cccgtctgcc aaacccggcg tgtacaaagg
     4021 aaaagtggta atttccgcag aaagcggctc tcccgtcagt gtgccggtaa ttctggaggt
     4081 ggcgccggaa tccctccctg ctcccgcgca ttggcaagtt catctggact tgtggcagca
     4141 tccgcaggcc gtggcccgct ggcatgatgt ggaaccgtgg tctccggagc atttcgcact
     4201 gatgaagccg gtgatgaaaa ggctggcgga tgccgggcaa aaggccatta catgctccct
     4261 gattgatgaa gcctggaatg cccagactta tgactggttc ccgcccatga ttgaatgggt
     4321 caagggcaaa aacggaacca tgcgctggaa ttacgccaat tttgacaagt gggtttcctt
     4381 catgatgaac gaggtgggcg tcaaggggca gatatcctgc tataccatga ttccctggaa
     4441 catgaaaatc cgttatctgg atgaggcgac cggaaagtac aaatttctgg atcttaagcc
     4501 gaacgatccc tcctatgaag ctatctgggg gcctttcctg acggattttc gcaagcacgt
     4561 caagagcaag ggctggctgg gcaaaacctg catcgggctg gatgaacggc cggacgctat
     4621 ggtcagggcg gccaagaatg tgctggacaa gtatgccccg gaattcaaaa tcgtttccgc
     4681 cgtcaatcgg cctacggcca tgacccggga cgtttatgac gtctctcctg taattgacca
     4741 tgcaggcacg gtcacgggcg atctgctggc gcagcgtaaa aaggagggaa aaaagacgac
     4801 gttctatgtc tgtgtccatc ccaaaaagcc caacaccttc actatgtccc cgctggcgga
     4861 ggcggaatgg cttcccctct ttgccgccgc caatcatttg gacggctttt tgagatgggc
     4921 ttataattcc tggaaccgta atccgtttga aaagaccgat ttcgggaact ggcccgcggg
     4981 agactgctac cttgtttatc ccggcaatct cagttccctg cggtttgaaa aactccggga
     5041 cggactggag gaatttgaaa aggtcaatat cctgcgcgcc cgcgccgcaa aaaatcctaa
     5101 ggcgaaagct gccgtagccc gcatggatga agagctttcc aagctcttta ccgtggaaaa
     5161 aagccgcggg gattcccatg aggaagacgt gcggaaagcc cgcgaaatta tccgtaaaac
     5221 gacggaaatt tcccgctgac ctttcttgcg ggaaaaaggg aaactgctgt atttccatgt
     5281 ctttccggag gttcggttaa gctccggaaa ggggggagga tcagcggttt tctctttggt
     5341 atttcgatcc ccattccgcc atggaggcca ggacggggcg cagactgcgc cccagttccg
     5401 taagagtata ttccacgcgc ggaggtactt ccgcatacac ctttcgcgta agcaggccgt
     5461 ccttttccat agaacgcagg ttcgcagtca gaactttctg cgtcacaggc ccaatggatt
     5521 tgcggagttc tccaaaccgc cgggtgcctt cgagcagatc gcggaggatg agcactttcc
     5581 agcgggagga aatcagttgg agagtagttt caacagggca tgatgaatta tagtaagtca
     5641 tttattttaa gcaatagttt ctttcaggaa tccagggtac tattttctgc ctactttaca
     5701 aaaagaatgt taccgcctat tttaataagt gcctgccgtt acggcaagca tgaacagata
     5761 atgccatgaa caagatcatc attgccaatt acagggagac ggagcctcag gttatcagcc
     5821 gggagggtaa ttcctttgcg gtaaagcccg tcatccggga agcggatgcc ggaaaatgtg
     5881 cggccagttt cgtggaagtg gagccggggc ggtacgccta tggctaccat tatcatgaag
     5941 tgaatgaaga ggtattttac atcatcaggg gccatgccgt tgtgcgtacg cctgagggtg
     6001 aaaagaattt aaaagagggg gatgcgattg cattccctgc cagcccggag ggagcgcatg
     6061 ttatccgcaa cggatccgct acggagaagc tggtctatct ggatgtgggc actcgcctga
     6121 cgcctgatgt ggtgcacttc ccggatacgg catccggaat ggtatattcc tcctccggtg
     6181 tgcaccattt tcgggaatct tgaagcagca tccctgtttt aaagcctttt tccggttttt
     6241 ccaccggcgc ggtccgcagg aaagcgggcc gcgctcctct ggggaggaag gtgtgaggaa
     6301 acagtattcc cctggccgca tgaaatgccc ctctttgcct tggacatggc tggccgcaaa
     6361 ggctgcggtt cattgaaggc cttcaaaacc tccatgcgga aattaacccg tataaggtga
     6421 tctattaaaa cccggccttg cagcaaggtg tgcgcccttt tttgtgctgc gggggaagga
     6481 tgaattctcc ggctttcagg aagggaaagt actggcgcgg gaagcctgct tgcgtggctg
     6541 tatggcgggg cggaaaagca gtcccctccc cgaaatattc atggtttgtt tttcatgaat
     6601 atccggcagt aaaaaacgcc cctgccggat aagccggaca ggggcgttga aattaagcgg
     6661 cctatacctt attccgcagg tttgtcggca cccatgccgg caatgctttg gtacaggttc
     6721 cagcggtgcc agacatcctt ctgggcttct tcaaggagtt tttcgaatcc ttccttattg
     6781 gtcttcgcca gaagtttgaa gcggttttcg ctgagcagca catcgcgcag atcgcccttc
     6841 gggcccttgc cttccacaat cagcggattc ttgccctggc gagccaggtc cggattatag
     6901 cggtaaagca ggactcggcc ggaatccacc catgccttct gctgctgcag gcccttggcc
     6961 atattgatgc cgtgggagat gcagtgggag taggcgatga tgagagccgg gccgtcatag
     7021 gcttccgctt ccacaaaggc tttcagcgtg tgttcgtcct tggcgccgag agcgacggag
     7081 gccacgtaca cgttgccgta agtcatggcc atgaggccca gatccttttt cacgccgggt
     7141 ttgccgttcg tggcgaattt ggctactgcg gcgcgcgggg tggatttgga gcactggccg
     7201 ccggtgttgg agtatacttc cgtatccatg accagcacct tcacgttccg gccgctggcc
     7261 agaatgtgat ccaggccgcc gtagccgatg tcgtaggccc agccgtcgcc gcccagaatc
     7321 cacacgctct tgcggacaag tttatccgca agggtcagga ggcgcgcgta ttccggcttg
     7381 ccggcaattt tcttcttgag ttcttcaatg ttttcacgct gctgggcgat gtctgcttca
     7441 tccttctgcg gattagccag tatccggtcc accagttcct ggcccacggc gccggcagct
     7501 tcatgaagaa gctcaatggc gtgttccatc tgcttgtcca gggagacgcg gaagccaagg
     7561 ccgaattcgg cgttgtcttc aaacagggag ttggcccagg cggggccgcg cccttcagag
     7621 tcatgggacc acggggtggt gggcaggttg ccgccgtaaa tggaggagca gcccgtagca
     7681 ttggcgacca ccaggcggtt gccgaagagc tgggagagca tttttacata cggagtttca
     7741 ccgcaaccgg cacaggcgcc ggagaattcg aacagcgggc gcagcacctg catagagcgg
     7801 atgttgtccg ttcttacctt ggtgcggtcc acgtccggaa ggctcaggaa gaaattccaa
     7861 ttggcttctt ccttgtcgtg aatcttcccg gccgggacca tggtcagggc cttgtacgtc
     7921 gggtccgtct tgctcttggc cgggcagaca tccgcgcaga gcgtacagcc cgtacagtcg
     7981 ttcggggaaa tctggatgac gaatttctct cccttccagt ccggatgctt ggcatccagg
     8041 cattcaaacc cttccggagc gtttgcaaga gcatcaggag agaagaattt actgcggata
     8101 accgcgtgcg ggcagacggc ggtacacttg ccgcactgga tgcagagggt cggatcccat
     8161 tccggcagat ccagggccag attgcgcttt tcgtactggg acgttccgtt cgggaatgtg
     8221 ccgtccacgg gcatttggct gaccgggatg ctgtcgcctt caccgcacat catcttgcca
     8281 aggacgtttt gtacgtagtc cggagcgtcc ggggacatgg cgggcggaat ggcgtgtccg
     8341 tttacagttt ttccggttgt gtccacctga tgcaggtttt ccagcgtggc gtccacggcg
     8401 gcgatgtttt tgtccaccac ttcctggccc ttcttggcgt aggttttggc aatggccttc
     8461 ttgatgtagc cgatggcttc atccgcggga atcacgctgg ccagcttgaa gaagcaggtc
     8521 tgcataatca tattgatgcg gccgcccatg cccgttttgc gggccacggc aaaagcgtca
     8581 atcgtgtaga gcttgatgtt cttgtccaga atctgctgct gcatgcgggc gggcagcgtg
     8641 tcccagagtt tgtccgccgg gtgcgggctg ttcatcagga aagtggcgcc gttggcggca
     8701 ttcttcagga agtcgaacag atccagcagg gaaggctggt gcagggccag gaagtttgcc
     8761 ttggtgatca ggtatgtgga tttgatcgga cggggaccga agcgcaggtg ggaaatggtg
     8821 gaggaacccg atttcttgga gtcatacacg aagtagccct gcacatacag gttcgtatgc
     8881 tggccgatga tcttgatggc gtccttattg gcgcctacgg tgccgtcgga accgaggccg
     8941 aagaacatgg cccgcgtcac gtcgtccgct tccgtggaat aatcttcatc atacgggagg
     9001 ctggtgccca gtacgtcgtc gttgatgccg atggtgaaat gattcttggg agtgtccaga
     9061 gccaggttgt catagacgcc cttgaccatg gcgggggtga attccttgga ggagaggccg
     9121 tagcgtccgc ctaccacctt gggcatgccg ttggtgaagg gcagcgtgcc gttggcctgg
     9181 gcgtcgaaga gggcctggat gatgtcctgg tggagcggtt ctccctggga gccgggttcc
     9241 ttggtgcggt ccagcacggc gattttcctg accgtagcgg ggagggcctt gacgagttcg
     9301 gcggcgggga aggggcggaa caggcgcacc ttcagcacgc ctaccttggc gttttcccgg
     9361 gtcatcatgg cttctaccgt ttcttccaca gcttcagcgc cggatcccat caggataatg
     9421 acgcgttcgg cgtccggagc gccggtgtaa tccaccagat ggtaggaacg gccggtaagt
     9481 tccgcaaatt tgtccatggc gttctggaca atagccggag tggcttcata gaaacggttg
     9541 accgtttcac gtccctggaa gtaaacgtcc gggttctggg cagtgccgcg cagaacggga
     9601 gcatcagggg tcagggctcg ttcccggaag gaatccagcc attcctgctt aatcatgccg
     9661 ttcagggtat cgtccgtgat gtctgcaatc ttgccgattt cgtgggacgt gcggaacccg
     9721 tcaaagaaat tgatgaaagg aatgcgggat tccagtgtag cggcgtggga aatagcggcg
     9781 aagtccgcag cttcctgagt ggaggagccg cacagcatgg cccatccgca ggagcgggcg
     9841 ctcatcacgt cgctgtggtc gccaaaaatg gaaagggcct ggtaagccag ggaccgggcg
     9901 gctacgtgga acacggcggg agtcagttcc cctgcgattt tgaacatgtt cgggatcatc
     9961 agcaggagcc cctgggatgc ggtgaacgta gttgcaagcg ctccggtctg gagggcgccg
    10021 tgaacggtgc ctgccgcgcc gccttcactc tgcatttcca ctacggaggg aacggtgccc
    10081 cacaggttct tcctgttgac agcggcccag ctttcagctg attcacccat cggagaagat
    10141 ggtgtaatgg ggtaaatggc aatgacttca gaaaaacgat aggctacaga agctacggct
    10201 tcgttagcgt caatcgtgct gtaagttacg gttgtctgat cactcataag tctgcacgga
    10261 tagtatataa ttgataaata aggtgcgtct taacggaaac atttataaca tgtctggtgc
    10321 caaaggtaaa agcaattatg cgtatgtggg gatttgccgg ccatttttta ataataagac
    10381 cagttttgtt tcaattcctt tgaatatcgt gctttatgtg gttctgtcca ggctttttgc
    10441 aaaacggccg gagtactggg gcatgttccg gcatccggct tccgaaaaag ggggggggag
    10501 gaaccttcgg gtcaaaaccg gctgccaaaa atgtcccctc tgcctgacaa tgcgctagcc
    10561 aaaacggaag caagccttta gaatccccgc actatgtccg aacaacagca ggcacatccg
    10621 actacgacgg aatccgaact tattgccgtg cgccgcgaca agctcgccaa aatccgtgag
    10681 ctgggaattg acccctacgg cgcaagattt gacgtgacca ccactcccgc cggattgaaa
    10741 gccgatttcc aggaagacaa acaggtagcc gtcgccggcc gccttctggc tattcgcgac
    10801 atgggcaaat cccagttttt cgtcattggg gacgtacggg gaaaaatcca ggggttcctg
    10861 cataaaaatg aggtggatga aaccacctgg aagctttgga agctcctgga ccgcggggac
    10921 tgggtcggca tcaggggaac cacgttcctg acccgtaccg gagaacctac cgtaaaggta
    10981 tccggactga ccattctttc caaaagcctc cgccccctgc cggacaagtg gcacgggctg
    11041 gcggacaagg aggtgaccta ccgcaagcgc cacctggacc tcatttccaa tgaggaaagc
    11101 gcctccctgt tcgttacgcg ctccctcatg attgcggaaa tccgccgctt tctccaggaa
    11161 cgcggttatc tggaagtgga aacccccatg cttcaggatg tggccggtgg ggccgccgcc
    11221 aagccgtttg aaacgtacca taacgcgctg gatatgccgt tgacgctgcg cattgccccg
    11281 gagcttttcc tcaaacgcct gatggtgggc ggcttcacga aaattttcga actcaaccgc
    11341 agcttccgca atgaaggaat tgaccgccgc cacaacccgg aattcaccat gctggaagcc
    11401 tattgcgcct gcggtgattt tgagaccatg gcgaatatgg tggaggagct catctgccat
    11461 ctggcggaaa aattctgcgg tggccttcag attgaccaca aggacgcgga aggcaacgtt
    11521 ctttacacaa tcgacctcag ccggccctgg agacgcgccg actaccagga cctgatccgg
    11581 ggcgtggcgg gggaagactg gtttgacatc tcccccgaag cgcgccgcgc ccgctgtgaa
    11641 gagctgggag tggaaatcag cccggatatg aaagatgtgg atgtttccca gcaggtgtat
    11701 gaaaaactgg tggaggaaaa gaccatgaac ccctgctttg ttacccacgt ggccaaggac
    11761 ctggttcccc tggccaagct gaaccgggaa aatccggacg tagtggacgt atatgaactg
    11821 gtgatcaacg ggcaggaaat ttcccccggc tattcggaat tgaacgatcc cgacgtgcaa
    11881 aaggaacgcc tggagcacca ggctgccggg gagacccagc gcgtggacta tgatttcatt
    11941 gaaacgctgg aatacggaat gccctccgca ggcggcatcg gtatcggcat cgaccgcgtc
    12001 gtcatgatgc tgacgggggc ctcttccatc cgtgacgtgc tgctcttccc gcagttgaaa
    12061 cgtaaggaca gttaatccga accaccggcc gcatggttcc ccgcaccccg gatattctgg
    12121 actgcgcttc cgcccaatgg attggcaaac gccgcgagca ggaagacgtg gttaaaagtc
    12181 ttcccgccgc cggcgggatg ctgggcatcg tgtgcgacgg catgggaggg catcttcgcg
    12241 gagattgtgc ctcctgtgtg gtggcgcagg aatttgccgc ggtatttgcg gaaagcggca
    12301 tcgaggatat cccggaacgt ttaacggcgg ctttgcatgc tgccaacagg gcattgtccg
    12361 ccattcagaa ggaaccggag gaatccggaa ccacattgct ggccgtcttc atccgcgacc
    12421 atttcctgtg gtggatcagc gtgggagact cccccctgta tttatggagc ggggcggaca
    12481 gctttcgcat ggaccggctg aatgaagacc attccatgag gccgattgcg gatagccttt
    12541 accggaaggg gaaaatgtca cttcagggtg cgctccggca gcgttgcatt ctccgttccg
    12601 ccgttatggg cggtcccatg gaactggtgg acatcagcgc catgcccctg ctcttgcatc
    12661 cgggagatgc ggtgctggcc tgctcggatg gcttgcaggt ttggagcgag ctgttgagag
    12721 aaccttcttt cctggctctt caaaaggcca gggattgttc cagcagggag ctggtgggaa
    12781 tcatcatgga acaggtgaag gatatgctgg agccccagca ggataatgcc tccgtctggg
    12841 ctgccgtcat gcggaaaccc tgcgagggcg gtaaataagc ttattccggc gaaggaagtg
    12901 cgggagcatg gttctgggcg ggcgggaaga tgttcgcgct gttcttattg cgccttaaac
    12961 agggcttttc cgcagaccgg ggcacggaga gtcttgaaaa tgaggatctg gaggaggctg
    13021 tcaggtatgg tgttctttta cgggagcaac ccctccggaa agaaccgggc cggaggtgat
    13081 ttccccattg tcatttgacc ggcgggggat taaaatgcac tccgcacaac atgattgcct
    13141 ggatagtttt ctattacctg atcggagcga ttccgttcgg ctaccttgcc ggcagaatca
    13201 gagggattga cctgaggcag cagggttccc gcaacatagg cgctaccaat gcgtggcgcg
    13261 tactgggctg gaagtggggc ctttccgttt tcattctgga cttcttaaag gggttcatcc
    13321 ctgtgttcgg cgccttgaac tggctgccgt tcctgacggg ggatgcgggc ggctgggatt
    13381 tcaatgtctt ggtagttctc tcctgtttcg ctgttatact aggtcatact tacacctgtt
    13441 tcctgggatt caggggagga aaaggcgtag cgacaaccgc gggggtttta tttgccctca
    13501 atccggtggt ggcttgcgta gctctggctt cttggctggt ggttatggga atctccggca
    13561 tcgtgtccct ggccagcctg gtggccgctg tggtgatgat cgccgccgga tggtggattt
    13621 atccgctttg ccaggacggg gatgtctccc cccagatact ttacgtcgcc tttttcacgg
    13681 tggtaggcgc actggtgatt ctcaagcacc gttccaatat cgcaaggctt ctcaacggaa
    13741 cggagcactc cttctattcc aaaaagtcca agtaagatga tgaatcggtt acataaaata
    13801 gcagtcattg gagccggttc ctggggcacg gccctctcca tggttctggc gacccgggaa
    13861 tgtgaagtcg tcctgtggac gccggaagag gctcaggcca ggcagcttgc cgaaacaaga
    13921 cgcagccccg tcctttcgaa aactgccctt cccctggccc ccaatatcca tcctacttgc
    13981 gatctgggcc aggtgaagga tgcggaactc attgtagtag tggtgccttc cgtagccatg
    14041 cgttccgtgg cccagcggct gcgcagcctg ccggtgcagc cggatgccgt catcgtctcc
    14101 tgcaccaagg gcattgaaca gggaacccat aaaagaatga cggaaatcct tcaggaatat
    14161 ctgccctcca accccatagg cgtgctttcc ggtcccaatc atgcggaaga tatctgcctg
    14221 ggccttccgt ccgcttcctt ga
//
