LOCUS       c00010_gnlPro..        14154 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CEGGAMPB_10.
ACCESSION   c00010_gnlPro..
VERSION     c00010_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 08:35:05
            Original ID  :: gnl|Prokka|CEGGAMPB_10
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14154
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14154
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[664:4154]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      665..4154
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14154
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14154
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(665..1432)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.5; E-value: 8.6)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_1"
                     /sec_met_domain="Fer2_3 (E-value: 2.5e-23, bitscore: 74.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 8.4e-11, bitscore: 34.5,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.8e-06, bitscore: 19.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKTLNLTLKVWRQENREAKGRIETYAAKDIPVDASFLEMLDIVN
                     EGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPERQVTTCQLHMRKFKDGDTVWIE
                     PFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAPNANNIAVEKVKADAAFDAAAC
                     IGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSKRVLAMMKQMEAEGFGNCTNQY
                     ECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(1473..3404)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.2; E-value:
                     4e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_2"
                     /sec_met_domain="FAD_binding_2 (E-value: 4.5e-54, bitscore:
                     176.2, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.3e-37,
                     bitscore: 120.9, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVLVVGSGLAGA
                     SAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKGGD
                     FRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRTFYARGQTGQ
                     QLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEIKSYAGDTVL
                     LCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVKGDYQSKLTL
                     MSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFGNLAPRDISS
                     RAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEITDDDPHETP
                     MMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQGLSDGYFVI
                     PATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFHRELGLIMWE
                     DCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVADFLEFAQLLC
                     YDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLHKEPLTFENV
                     HLAIRSYK"
     CDS             complement(3453..4154)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg10_3"
                     /sec_met_domain="SucD_FumR (E-value: 2.9e-13, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             4355..4627
                     /locus_tag="ctg10_4"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             4660..5445
                     /locus_tag="ctg10_5"
                     /transl_table=11
                     /translation="MVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSADGFRDYFVQLT
                     ECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLGIGEIGLNRNT
                     SHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLDPCRVLVDHCE
                     EHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADWGDSDPLALTA
                     LACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(5479..5712)
                     /locus_tag="ctg10_6"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPD
                     EFLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(6141..6848)
                     /locus_tag="ctg10_7"
                     /transl_table=11
                     /translation="MNKLLSTLILSAGMSLSATAATSLLDSSIVGYSDFASQTADFGTL
                     KDSVSITSDDSNLTLSGITFNGYGANNRDVMSVTMVLDLSKINTPEAYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYNGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSATYYS
                     NSGLKFGNQQIDQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             complement(7068..7163)
                     /locus_tag="ctg10_8"
                     /transl_table=11
                     /translation="MQYNIHLPYYNETFLYGYGFGIPQSDLESVK"
     CDS             7274..8626
                     /locus_tag="ctg10_9"
                     /transl_table=11
                     /translation="MMEGLMPYRDLFDQKGPFIFLIYGFSYALCGSYWLVFVLEVFAVT
                     ASMIFCYKAALLFVSGKKAFIVSLLILYSMCSFHYYAGGGHPSEFILPFQFAAIYGVCR
                     LYRDPDRFVRTGVVFGAGIGMALLLKFNLAAFWFVPFLYVLYRARMTGKAWIFTGSVGG
                     TLLLMLTPCLWYFYSRGALLDLYEGYIVFNAGYGADAVSFKEMCRNYSQWVKRDIMYPS
                     MLMYIVGGAGVILSRMPAREKIYYTAAFLITCMGVQGNGKTHFNHYAQTLIPFAAVGYL
                     VVARMIHVEEVVSRKWRRWLFPLVVAGVMACTFLNCVDFSCRSRAREWMSAFALPDTSD
                     EPGGENACAVLGRHAVWFYCVNGLVPPIRTFTICASDKQGAERERMRQYQEIRRGKIDY
                     VVIAGEYFKPDNTESPSLRAMRDLLSTEYCRERSFFREVTNLDIYRRVKRD"
     CDS             complement(8623..9507)
                     /locus_tag="ctg10_10"
                     /transl_table=11
                     /translation="MTLFLAGPTGSGKSAVAVELAEMLDAEIVSSDAYQVYRELPILTA
                     APSPADRERVPHHMVSIIPVQRNWNATEHYHRAMRCMEEIHARGKIAIVTGGSGLYFKF
                     LSHGLSEAPPGDAALRAAFANCSTEALYARLSSLDPEGAASTDASNRRYVERNLEIVLA
                     GGKPLSFWKRNWLTPPRGPGWVISRDVPELDERIAHRAARMMQEGAVEETASLGPCSAT
                     AERTLGLALIRSMLRGEISRENCQGQLALATRQYAKRQRTWLKREQWLRKLPASPSDSP
                     RALAERIMEELGH"
     CDS             complement(9591..10331)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_11"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 1.5e-10, bitscore:
                     33.9, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFPKKIKACILFLLLTVPAALGAVWCAKHAYRYHLAVHPLPYSPE
                     QGALLEKHRQDKRNARLNPHAPVLFLGSSTMEFWLKEGKHSWETWFSPLGCLNLGTRSE
                     TTGNLLWRLNDGLTSPLAPRIIVLYSGVNNLGVQKSLGWTAFQGNVAIVKKIREIYSPE
                     TTAIIVIPPLIAQKGSRMETFRNCLLQHDFGENVHVLPLHFFLPGKDASLYTWDGLHLN
                     ALGYEAISPPLFRFLQQLLSRSSF"
     CDS             complement(10312..11415)
                     /locus_tag="ctg10_12"
                     /transl_table=11
                     /translation="MTPQNPTILLPSSREHWIDISRFLAACLIVCVHAPAFSFASLFQL
                     PVFNGRVAFFLILAGYFMGRNNSWNKAFKRGYTLLIPFLFWNIVISFLHPGIMNMGLPE
                     YLCNLAGFRSLFTPDFIPLSINGLTGEPFSPPTWFLRDIILCSLISPILLKLKYPVFVL
                     ILICFSTDWLQYPVPANKITLAPSTVSLFSLGLFLSSIKLAEVKHVYKNSFTPLVLLAV
                     GTGFLLSITNYLSVCQNNPEWNMHKILASYGVWNISWPAVHLNSLCPVFGALLLMALGI
                     WLEKKIPVARKLSNYAPACFLIFVLHYPLIMLIPSHIWKQSFFAPFVLIPAIIFLIVAF
                     YLFLRKFFPACLPYVANDRITHVPKKN"
     CDS             complement(11462..12079)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Hexapep_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg10_13"
                     /sec_met_domain="Hexapep_2 (E-value: 7.4e-15, bitscore:
                     46.7, seeds: 55, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLFLIHLLSGIGRLLLRLRGVRTGTGIILSGFPLIKKFPGASIT
                     IGNGVTIHSLTRMNPVLSHHTCLAALSHQASIILEDGCGISGATLVCVNGIRIGRHTLI
                     GADALILDNDMHYPRSGARWGSTLGKPEQGQPISIGEGCFIGARATILKGVTIGSGSVV
                     AAGAVVTRDVPPGCLAIGNPAVNKPLPERLKHPRETQKAICP"
     CDS             complement(12079..13224)
                     /locus_tag="ctg10_14"
                     /transl_table=11
                     /translation="MPIKRLRPVLAIAADLPLGRLLTSFRNKDRRTIPWIFSLFHALES
                     QEDFDIHWITLSKAVSAPETIRMRNQTIHILPLGSMGRNILTAHFLTVRRIRKTLNDIQ
                     PDLLHVWGVEQAYALAGIAFRGKKLLSYQGALTAYCQRAPQAFLLHMQALWERMAVKHY
                     DLITCESPWACGRVAEIAPHARLSCMEYGVEPSFYHLARKPSPEPSCLFAGTIYELKGI
                     SYLVEAFTHPSLSHVQLFIAGNGALRERLEALSTPNIHWLGSISRAELQQHLSTAWFLV
                     HPTLGDCCPNIVKEARVMGLPVITTEEGGQTQYVQDGVSGYIVPVRNSAAIREAAQKLS
                     VSLDKTMSMGMERHQECRRLLDVKQTVTGCLSRYHTMLYPH"
ORIGIN
        1 gagctgcctc catgccccgc ctgccggggc tgccgccggc tccaaagtac catttccggt
       61 aagcgggaac ggcagaacga tgggcggagg aggaacgatg aggcggattc atcaggtatt
      121 caagagtcgg gggtaatgaa ggaagcgagg ggggccgccc tttcctgatc gttttatcaa
      181 tagtatgatc tgaagtcggt gtcgatagaa ttttatttgt atgtttttga ttttttataa
      241 aagatggtca ttattttaca cgaaaagata atattataat tcttacgttc agtgcattcc
      301 cttaatagac atcaatgttg tctgtttgtt agaaaatgtt ttcctctcat gctgagccct
      361 tgacaggagg ccatcccttc cgggcatcag tccaattcct gtaatcaatg tttctttctc
      421 tcgaagaaag atgggggccg tcgctgtcgg acgggggctt gcttaggttt cgtccggcat
      481 ttccaagtac ggtctcctgg attactgggt gccttccggt gtaacaattt tttacgctgc
      541 gcgacgatga ggaagcaact gtctggtatt ttattcctgg ttcaaggaaa tctggtaatg
      601 aaaaaactcc cgacagccga tgccgccggg agtttttaca gagcgtctta agaaggaatc
      661 ttctttagaa acagaggcct tccttggcgt tggcccgcat gaagtcgcgg ttgaggcggg
      721 cgatgttgtc cacgctgatg cctttcgggc aggcggcttc acattcatac tggttcgtgc
      781 agttgccaaa gccttccgct tccatctgct tcatcatggc caggacgcgc ttggaacgtt
      841 ccggctggcc ctgcggcagc agattgagat gggcgatctt ggcggaggtg aacagcatgg
      901 cggaagcgtt tttacaggag gccacgcagg cgccgcagcc gatgcaggcg gccgcgtcaa
      961 aggcggcgtc cgccttcact ttttccacgg cgatgttgtt ggcgttcggc gcggaaccgg
     1021 tacgcacgtc aatatagcct ccagcggcga tgatgcggtc cagggcggag cggtccacca
     1081 tcaggtcccg caggattggg aaagccttcg cgcggaaggg ttcaatccag acggtatcgc
     1141 catccttgaa cttgcgcatg tgaagctggc aagtggtcac ctggcgttcc ggcccgtggg
     1201 gaatgccgtt gatggtcagg gagcacatgc cgcagatgcc ttcccggcag tcgtggtcaa
     1261 aatggatggg ttccttgcct tccttgacca ggccttcatt gacgatgtcc agcatttcca
     1321 ggaaggaggc gtccaccgga atgtccttgg cggcataggt ctcaatgcgg cccttggctt
     1381 cccggttttc ctggcgccag accttgagag tgagattgag tgttttagcc atgttataat
     1441 ctttcttttg agtgttaatg tattggctat ctttacttgt agctgcggat ggcaaggtgc
     1501 acgttctcga aggtcagcgg ttccttgtgg agaacaggca ggctgtccac gccagtgtat
     1561 tcccaggcgg ctacataggc gtattcatcg tcgttgcgct tagcttcgcc gtccggcagc
     1621 tggtattcca cgcggaagtg ggcgccgcag gattcctggc ggttcagggc gtcatagcag
     1681 agcagctggg cgaattccag gaagtcggcc acgcggcagg ctttttccag ttccgcgttg
     1741 atgccgtccg ccgtgccggt tacgcgcacg ttttcccaga attccttgcg gagctgggga
     1801 atgcgttcaa tggcgtgggt caggctttct tccgtgcggg ccatgccgca gtcttcccac
     1861 atgatgaggc ccagttcccg gtggaaggag tccaccgtct tggtgccctt cacattcagg
     1921 agcttgttga tgcgttcctt cacttcgtct tccgcagcct tgaattccgg ggcggcggtg
     1981 gtgacggcgc cgggcttggt ggtcgtcagg taagcgggca gcgtggcggg aatgacgaag
     2041 tagccgtcag acaggccctg catcagggcg gaggctccca ggcggttggc gccgtggtcg
     2101 gagaagttgg cttcaccgag gacgtgcagc cccttcacgt tggacatgag gttgtagtcc
     2161 acccacaggc cgcccatggt gtagtgggag gcggggtaga tcatcatggg cgtttcatgg
     2221 gggtcgtcgt ccgtgatttc ttcgtacatg tcaaacagat tgccgtattg gccgtcaatc
     2281 cattcgcggc ccatgcgctt gatttcatcc gcaaaatcca ggaagacgcc cttgccggtg
     2341 acggccacgc cgcggccgtc gtcgcaggct tccttggcgg cgcgggagga aatgtcgcgc
     2401 ggagccaggt tgccgaagga gggatacttg cgttccaggt agtagtcccg ttcttcttcg
     2461 ggaacatcgg aaggcttgat ttccttttta cggatttttt ctgcggtttc acgggacttg
     2521 ggcacccaga tgcggccact gttgcggagg gattccgaca tcagcgtcag tttggactgg
     2581 tagtcgccct tgaccggaat gcaggtgggg tggatttgcg tgaagcaggg gttggcgaag
     2641 aaggcaccgc gcttgtaggc cttgtaggcg gcagtgacgt tgcagcccat cgcgttggtg
     2701 gacaggaaga acacgttgcc gtagccgccc gtgcagagca ggacggtatc ccctgcgtag
     2761 gatttgattt cgccggtaac cagattgcgg gtgacgatgc ccttggcttc gccgtccacc
     2821 agcaccagat ccatcatttc atggcgggag aacatttcaa tgtgtccctt ggccacttcc
     2881 ttttccaggg cctggtaggc acccagcagg agctgctggc ccgtctgtcc gcgtgcgtag
     2941 aaggttcgct tgagctgggc gccgccgaag gagcggttgt ccagcaggcc gccgtattca
     3001 cggccgaagg gaacgccctg ggccacacac tggtcaatga tgttggagga gacttccgcc
     3061 agacggtaga cattggcttc acgggcgcgg aagtcgccgc ctttaacggt gtcgtaaaac
     3121 aggcggtaaa cggagtcgcc gtcgttctgg tagttcttgg ctgcgttaat gccgccctgg
     3181 gccgcaatgg agtgggcgcg gcgggggctg tcctggtagc agaagcattt gacgttgtag
     3241 ccaagttcgg caagcgtggc ggcagcggag gcgccagcca ggccggaacc taccacaagc
     3301 accgtgtact tgcgcttgtt gttcggattg atcagtttgg actcaagttt gtacttggac
     3361 catttgtcct gaatagggcc ggagggaatt ttggcatccg gcatccagtc gcttacggga
     3421 aaattaatca tgactttgag aggagttgat ggttatttga tgatacccag aagaaccgag
     3481 accggcacgg agatgaagcc caggcagata atcgcgccgt aggcgatggc gataaagttg
     3541 tagaagggcc ggattttgcg ggaatcgacg cccacagtct ggaagatgga ctgtaccccg
     3601 tggcgcagat ggctgaacag catcagaacg gccaggatgt agaaggcgga gcaccatacg
     3661 ttggagaatc cggtcacgat catcttgtac acgtcaaagg tttccaccgt accgtcggaa
     3721 atgaaggtgg tgaactgggc ggggtcgtat cccacgcgca gggtgtactg gtacaggtgg
     3781 tagatcagga acaccaggac ggtcaaaccg gtatagatca tgtagcggga ggagagcgtt
     3841 gccttaatgg tgttcttgaa cacgtagggt tcgcgggccg catggttttc cagcttcagc
     3901 tggatggtca gccagacgtg gatgatgaag atcaccgcaa gccccgcgcg gattccccag
     3961 agggctgctt ccggcatgga gtgcaggccg tgggcgtagg tgttgatcca ttcagggcct
     4021 ccgaagatga gaaggttgcc tgccaggtgt cccgcaagga acaagaccaa acataacccc
     4081 gtcagagcca caatgatttt gcggccgatg gaggatgtca cgaatgtaca tatggttttt
     4141 actagtgcat tcataggcgc tctaatgaaa taaatgcgtc ttcacaggat gcccggttca
     4201 agcccggatg gcaagcctct tcttgaattt ccggcgcttt tcggattttt gaaaaaccgg
     4261 ggaaagaggt tgctgtttat cagtttggaa tggttatcat tttgttgcct gttccggctt
     4321 gacgaggctt tccgcatagg cgtatcgtct gtgcatgaaa agaagtaaaa aggaggtgct
     4381 ggacgcggat ttcgcagcgg cgcgcgccgg cgttctggat gtggccgcat ttctggaccg
     4441 ggtggaccgc ggggaagggg aggcggattt ccgctaccat gccctgatgg atgttcttcc
     4501 cctcttgtcc gcatccggcc ccggacgcgt ccgggccatt ctggaagccc tttcctacag
     4561 ggatgacacc gtgccggaaa ccgccgcagc caaagcggcc tgcggagccc cgaacctcag
     4621 caaataagaa tgatggcttt catagaacct catatacata tggtgtgccg caccacggac
     4681 gaataccggg ccatggcgca ggccggctgc ctggcggtag gggaaccggc gttctgggcc
     4741 ggttacgacc gttcgtccgc ggacggtttc cgggattatt tcgtacagct tacggaatgc
     4801 gaacccgcca gggcggccaa gttcggcatg gaccattaca catggctgtg catcaatccc
     4861 aaggaggcgc aggacgtggc tttcgcgcgg gatgtgatga aactgattcc ggagttcatt
     4921 gaccggccca atgtcctcgg catcggggaa atagggctga accggaatac ttcccatgaa
     4981 atgactattt ttgaagagca tctggatctg gcggtgcgcc tcaaccagct tgtgctgatt
     5041 cacactcccc atctggaaga caagcttaag gggaccgtaa tgattctttc cgccctgaaa
     5101 aaccgtccgg atctggaccc ttgccgcgtg ctggtggatc actgtgagga acataccttc
     5161 ccgctggtga aggaggccgg ttactgggcc gggctgaccc tttatcccac cagcaagctg
     5221 aatcccaagc gggcggcgga tattctggaa ttgtacggaa tggaccgtgt ctgggccaat
     5281 tccgcggcgg actgggggga ttccgatccc ctggcgctga cggccctggc ctgcgagcta
     5341 cgcaggcgcg gtttttcccg gcaggaaacg gaacgtcttc tcctggaaaa tccggagaca
     5401 ttcatgggac agtccccgaa gttccggaaa gtgtcgtccc gctaattccg cccgaggcgc
     5461 ggcggagggt acggccctct agtccccgtc cgggaaaaag acggtgagga cggcgcccag
     5521 gatgaccgcc gcgtcatcca gaaggcccag cctgccgatt ccgtcaaaca ggaattcgtc
     5581 gggagtcagg atgtaggcgc cggcggcggc cagaaggcat atattccgtt tgttgaaaaa
     5641 acgcggttct ccttttctgc ttttgaaata ccggaacagg cgcagtagca gctgctgttt
     5701 ttgaaggttc atggacggga acgggggata aaggttcaag ctcagccatt ttcccactcc
     5761 ttttccctgt ttcggggaag gagtctgttg ccgacggacg gaaccgcagc gatccggacc
     5821 gtgcggggaa atggattgct gaaaggatgg gctgttccgg atgctgaggg aagccgggct
     5881 ttgcatgctc cggttccggc tgtcccggca tgggaaaaag gggcgtgtac ggaagtgggg
     5941 cggggccgga agctcttgaa atgaccctac cgggggagac tgaatgccat ttttccgtca
     6001 agtgctggcc gtgaggttgc cgcagcaaat ggaagctttt cccctctgtt ttttcggcag
     6061 atgtttgaac ggataaggaa aaggccggct cacgattttg tgagccggcc tttgaatata
     6121 gggaggcgga cggtacaggc ttatgccctg cggcggcgca tcatcagcgc ggccagtccc
     6181 agcaggccca gggaagccgt ggcgggttcc ggaatgctgg cgatttcact catcagctga
     6241 ccaacttgtt cctgggaaag gagggagtcg tggatgtaga gctgttcgat ggattcagcc
     6301 agtcctgcgt ccatgagaat ctgatcaatt tgctggttgc cgaatttcag gccgctgttg
     6361 gaatagtacg tagcgctgtc gccaaaatag atgcgggtgc caagatctcc ggtgactacg
     6421 gaaatggtca gggaaccttc cgtgcccagc ggggtgtcaa cgacgggccc gttgtatgag
     6481 gtgttgttcc ataatccctg gagtttccgg tccgtgttca ggcccacgcc ccagcttaca
     6541 ctgctgtttt tggcgttaaa cagagcggta taggcctccg gagtgttgat tttggacagg
     6601 tcaagaacca tcgtcacaga cataacgtcg cggttgttgg caccgtatcc gttgaaggtt
     6661 atcccggata acgtcagatt gctgtcgtca gacgtgatgg aaacggaatc tttcagggtg
     6721 ccgaaatccg ccgtttggga ggcaaagtcc gaatatccca cgatggagct atccagcaga
     6781 gaggtagccg cggtagcgct caggctcatg ccggccgaaa gaatcagggt ggataataat
     6841 ttattcatgg tcagtatctt aataaaatga ttcaaggttc aatgtatgta cttgtgcttg
     6901 aataacgaat ttggaatccg caagcaatta aaaatattaa gagttagtat attgtgttta
     6961 taattcattg aaaataatga ttttttaata tctctggtcc ttttgtcaag atgacgggtc
     7021 agtctttgtt attcattggt ttcatgattg atttggcctc tttttcatta cttgacggat
     7081 tccaaatccg attggggaat tccaaatccg tacccatata aaaatgtttc gttgtaatag
     7141 ggtaaatgga tgttgtattg catggtggtc tattttctca tttctgattt gttattattc
     7201 cagttatgtg tctccctatt atgaaattcc cgtaagttgt gatcccatta tttatcatct
     7261 catgggacgc ggaatgatgg aagggttgat gccttatcgg gatttgtttg atcaaaaggg
     7321 gcccttcatt tttttgatat atggcttttc ctacgccttg tgtggttctt actggcttgt
     7381 attcgttctt gaggtattcg cagtgacggc ctccatgatc ttttgttaca aggcggccct
     7441 tctcttcgta tctggaaaaa aagcgtttat cgtttcgctg ctcatccttt attccatgtg
     7501 cagtttccac tattatgcag gaggaggtca tccctccgaa tttattctgc ctttccagtt
     7561 tgccgcgatt tatggagtgt gccgcctgta tcgggatccc gatcgcttcg taagaacggg
     7621 cgtggtgttt ggcgcgggca tcgggatggc gcttctgttg aaattcaact tggccgcttt
     7681 ttggttcgtt cccttcctgt atgtcctgta tcgtgcgcgg atgaccggga aggcatggat
     7741 ttttacagga agcgtgggag gaacgctcct gttgatgctg acgccctgcc tctggtattt
     7801 ttacagccgc ggcgcgttgc tggatttata tgaaggatac attgttttta atgccggtta
     7861 cggcgccgat gcggtatcgt tcaaggagat gtgccggaat tattcccaat gggtgaaaag
     7921 ggatatcatg tatcctagca tgttgatgta catcgtggga ggagcggggg tgattttaag
     7981 ccggatgccc gccagggaaa agatttatta tacagccgct tttctgatta cctgcatggg
     8041 cgtccaggga aatggaaaga cgcatttcaa ccattacgcc cagacactta ttcccttcgc
     8101 tgctgtggga tacctggtgg tggccaggat gatccatgtg gaagaggttg tttcccgaaa
     8161 gtggcgccga tggctttttc ctctggttgt tgcgggagtg atggcttgca ccttcctgaa
     8221 ttgcgtggat ttttcatgca gaagccgcgc ccgcgaatgg atgtccgctt ttgctcttcc
     8281 agataccagt gatgaaccgg ggggggagaa tgcttgtgca gtccttgggc ggcatgccgt
     8341 atggttttac tgtgtcaatg gtttggtgcc gcccatacgc acgtttacga tttgcgcttc
     8401 cgacaaacag ggtgcagaac gggaaaggat gcgtcagtat caggaaatcc gccgcggaaa
     8461 gatagactat gtggtgatag cgggagaata cttcaagccg gacaacacgg aatctccctc
     8521 cctgagggct atgcgggatt tgctaagtac ggaatattgc cgggaacgat cctttttcag
     8581 agaagtgacg aacttggata tttaccgccg tgtgaagagg gattaatgcc ccagttcttc
     8641 catgatgcgt tctgcaagag cccggggaga gtcggaaggg gaagccggaa gtttccggag
     8701 ccattgttcg cgtttcagcc aggtgcgctg ccgtttggcg tattgccggg tggcgagggc
     8761 cagctggccc tggcagtttt cacgggagat ttccccgcgc agcatgcttc gtatcaacgc
     8821 caggcccagg gtgcgttccg ctgtggcgga gcatgggccg agggaagccg tttcctccac
     8881 ggccccctcc tgcatcatgc gtgcggcacg gtgggctatt ctttcgtcca gttcaggaac
     8941 atccctgctg atgacccagc cgggcccgcg cggcggggtc agccagttcc tcttccagaa
     9001 ggaaagaggt ttccccccgg caaggacgat ttccagattg cgttccacat aacgccggtt
     9061 ggaggcatcc gtcgaggccg ctccttccgg atccagggaa gagagtctgg cgtatagcgc
     9121 ttccgtggaa cagttcgcga aagcggcgcg gagagcagcg tcccccggcg gcgcttccga
     9181 caggccgtgg gagaggaatt tgaagtacag gccggaaccg cccgtgacga tggcgatttt
     9241 tccgcgtgcg tgaatttctt ccatgcagcg catggcgcgg tggtagtgtt ccgtggcatt
     9301 ccagttcctt tggaccggaa tgatggaaac catgtggtgg gggacccgtt cccggtctgc
     9361 cggggaaggc gccgccgtca ggatgggcag ctcccggtac acctggtaag cgtcggaact
     9421 gacgatttct gcgtccagca tctccgccag ttccacggct accgcggatt tgcccgatcc
     9481 ggtgggacct gccagaaaca gggtcatggg aagtgttgcc tgatggggtg gagaagattc
     9541 aatcatcacg tggagtaatg gcggataaag tttgttgttc ctgtgaagcc ctaaaagctg
     9601 ctcctgctta aaagctgttg gaggaagcgg aaaagcggag gcgaaatggc ttcatatccc
     9661 agggcgttga gatggaggcc gtcccaagta taaaggctgg cgtcttttcc cggaaggaag
     9721 aaatggaggg ggaggacatg gacattttct ccaaagtcgt gttgcagcag acaattcctg
     9781 aaggtttcca tgcgcgaccc tttttgtgcg atgagcgggg gaatgacaat gatggcggtc
     9841 gtttccgggc tgtaaatctc cctgattttt ttgacgatgg ccacgtttcc ctgaaaagcc
     9901 gtccatccca ggcttttttg tactcccaga ttgttgactc ccgaatacag gacgatgatt
     9961 ctgggcgcca gcgggcttgt caggccgtca ttgaggcgcc agagcaggtt gcccgtggtc
    10021 tcgctcctgg ttcccaggtt gaggcatccc agaggggaaa accaggtttc ccaggaatgt
    10081 ttcccttctt tcagccagaa ttccatggtg gaggaaccca ggaacaacac gggggcatgg
    10141 ggattcagcc gggcattgcg tttgtcctgc cggtgttttt ccagcagggc gccctgttcc
    10201 ggggaatagg gaaggggatg gacagccaaa tggtagcggt aggcgtgttt ggcgcaccag
    10261 acggcgccta atgcggccgg aacggttaaa agaagaaaga ggatacaggc cttaattttt
    10321 tttgggaaca tgggtgatgc ggtcgttggc gacgtagggc aggcaggccg ggaagaattt
    10381 tctcaggaaa agatagaatg cgacgatcag gaaaatgatg gccggtatta atacaaaggg
    10441 agcgaaaaag gattgtttcc agatgtggga ggggatcagc atgatcaaag gataatgaag
    10501 aacgaatatc aggaaacagg cgggagcata gttggacagc tttctggcaa cgggaatttt
    10561 cttttccagc cagattccaa gggccatgag aagaagcgcc ccgaagactg ggcagaggga
    10621 attcaaatgg acagccggcc aggagatatt ccatactcca taggatgcca gtattttgtg
    10681 catgttccat tccgggttat tctggcaaac gctcaagtaa ttggtgatgc tgagcagaaa
    10741 cccggttcct acggcgagca ggacgagggg agtaaaggaa tttttgtaaa cgtgttttac
    10801 ttcagccagt ttgatggaag acaggaaaag gcccagactg aacagggaga cggtggatgg
    10861 agcaagggta atcttgttgg ccggcacggg gtattggagc cagtccgtgc tgaagcagat
    10921 caggatcagg acaaaaaccg gatatttcaa tttcagcagg atgggggaaa tgagggaaca
    10981 gagaatgata tccctcaaaa accatgtggg aggggaaaag ggttctcccg tcaatccatt
    11041 gatggaaaga ggaataaaat cgggagtgaa aagggagcgg aagcctgcaa ggttgcataa
    11101 gtattccggc agtcccatat tcatgattcc cggatggagg aaagagatga ctatattcca
    11161 gaacagaaag ggaatgagaa gcgtataacc ccgtttgaac gctttgttcc aggaattatt
    11221 ccggcccatg aaatagcctg ccagaatcag gaaaaatgcc acgcggccgt tgaaaaccgg
    11281 aagctggaac aggctggcga aagagaaggc cggcgcgtgg acgcatacaa tcaggcatgc
    11341 cgcgaggaat cgggatatgt caatccaatg ttcccgggat gagggtaata aaattgtagg
    11401 attttgcggt gtcatgaaag agtctgcctt tggagccccc tgaggcaggc aggggaaatg
    11461 ctcaagggca gatggctttt tgtgtttccc ggggatgttt gagacgttcg gggagcggtt
    11521 tatttactgc gggatttccg atggccaggc agccgggagg cacatcccgg gtgacgacgg
    11581 ctcctgcggc gactacggaa ccggagccga tggtgactcc tttcaagatg gtggccctgg
    11641 cgccgatgaa gcatccttcc ccgatggaaa tgggttgtcc ctgttcgggc ttccccaggg
    11701 ttgatcccca cctggcgccg ctccggggat agtgcatgtc gttgtccaga atcagcgcgt
    11761 ctgctcctat cagcgtgtgg cgtccgatgc ggatgccgtt gacgcagacc agggtggctc
    11821 cgctgatgcc gcagccgtcc tccagaatga tgcttgcctg atgggaaagg gcggccaggc
    11881 aggtgtgatg ggaaagtacc ggattcatcc gagtcaggga gtggatggtg actccgttgc
    11941 cgatggtgat ggacgctccc gggaattttt taatgagggg aaatccggaa agaatgatgc
    12001 ctgttccggt gcgcaccccc ctgagcctga gcagcaggcg gcctatcccg gaaagcagat
    12061 ggataaggaa taatttcatc agtgtggata cagcatggta tgataacgtg acaggcaccc
    12121 ggttactgtc tgctttacgt ccagcaggcg gcggcattcc tgatgccgct ccattcccat
    12181 ggacatggtt ttatccaggc tgacggaaag tttctgcgcg gcctccctga tggcggcgct
    12241 gttgcggaca gggacaatat agccggatac gccgtcctga acatattgag tctgtccgcc
    12301 ttcttccgtg gtgattaccg gaaggcccat gactcttgcc tccttcacga tgttggggca
    12361 gcaatccccc agggtgggat gcaccaggaa ccacgccgtg gagaggtgct gctgaagttc
    12421 tgcgcgggaa atgctgccca gccagtggat attgggagtg gacagggctt ccagcctttc
    12481 cctgagggct ccgttgcccg caatgaacag ctggacatgg gaaagggacg gatgcgtaaa
    12541 ggcctccacc aggtaggaaa tgcccttcaa ctcgtaaatg gttccggcaa agaggcagga
    12601 aggttccggg gaaggttttc tggcaagatg gtaaaaggaa ggttccacgc cgtattccat
    12661 gcaggataga cgggcatggg gggcaatttc cgcaacgcgg ccgcacgccc agggggattc
    12721 gcacgtgata agatcataat gtttgacggc catccgttcc cagagggcct gcatatggag
    12781 gaggaaggcc tgcggagcgc gctggcagta ggcggtgagg gctccctggt aggaaaggag
    12841 cttctttccc cggaaggcaa tccccgccag agcgtaagcc tgctccacac cccatacgtg
    12901 caggaggtcc ggctggatat cattcagggt cttgcgtatt ctccggacgg tcaggaaatg
    12961 ggccgtcagg atattcctgc ccatgctgcc caggggaaga atgtggatgg tctggttgcg
    13021 catccggatg gtttccgggg cagaaacggc tttgctgagg gtgatccagt ggatgtcaaa
    13081 atcttcctga gattccagag catgaaaaag ggaaaaaatc cagggaatcg tacgccggtc
    13141 cttattacgg aaagacgtca gcagccggcc cagagggagg tccgctgcta tggctaatac
    13201 gggacggagg cgtttgatcg gcatggattg gaaagaggag gcaaggttag caggtgggta
    13261 aatgctcccg gacgatggaa gatgcgaacg gaggctttcc ttccgggcgg atggaggaaa
    13321 aaagcagttg ctcccattcc tggtttactg cgtcgggggc gaaacaggct tcccattgcc
    13381 ggcggccttt actccccagt agtttgcgtg ttttttcgtc cgtcaacgat tccacggctt
    13441 ttcccagcac ggagggggaa gtgtttttca ggacgattcc cccctccagg gtggaaagag
    13501 ctcctgcgtc cggagcgaac cagggaacgc cgcatgacat cgcctccaga atggagaggg
    13561 gctgctgttc ctgataagag taaaggaaaa cggcatcgct ttccataatg gcggcttcta
    13621 cttccaaacg ggggagcctg tagagaatcc tgaatctggg gtcatccccg atggcttgtt
    13681 ccatttgttc cgcgtaggca ttgtgctggg gaatcagaaa aagaaaaatg atatgccgca
    13741 gacgggagcg tttcacatgg cggatgaaga gaagctgccg tttcctcatg ctggcgccgg
    13801 cagggcaggt aaaaacgggg gcggaggaaa gtccgtattt ttcccggaaa aaaggagcgg
    13861 ttcttttcag agccgggaat gtgttgggaa tgcaggagta atgggcaagt ttgcttctgg
    13921 atgcgcagta ataatcaaag ctcttgaaca gtgtcccgta aggatcgaga aaaacgagac
    13981 ggtttaacgg tgatttccgg catacgttga ggatatccct gcgtacttga aaaaaggagc
    14041 agagccattt tttcaggccg aagaaaggag ggtaattgaa gcggaaaaaa gagcggaaat
    14101 tggtagctgc accatgggag cggagaaaaa acggaatgcc tgaatcccgt gccg
//
