LOCUS       c00045_gnlPro..        13703 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NCIMCMEO_45.
ACCESSION   c00045_gnlPro..
VERSION     c00045_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 06:58:00
            Original ID  :: gnl|Prokka|NCIMCMEO_45
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13703
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13703
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[514:4093](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      515..4093
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..13703
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13703
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(3..170)
                     /locus_tag="ctg45_1"
                     /transl_table=11
                     /translation="MSEQQQAHPTTTESELIAVRRDKLAKIRELGIDPYGARFDVTTTP
                     AGLKADFQEDK"
     CDS             515..4093
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_2"
                     /sec_met_domain="PFOR_II (E-value: 3.3e-18, bitscore: 55.4,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 2.5e-79, bitscore: 255.6,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 9.4e-33, bitscore: 103.1,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2e-12, bitscore:
                     36.6, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 6e-14, bitscore: 42.3,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 6.5e-11, bitscore: 31.5,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.1e-06, bitscore: 17.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.7e-26, bitscore: 81.3,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDQTTVTYSTIDANEAVASVAYRFSEVIAIYPITPSSPMGESAE
                     SWAAVNRKNLWGTVPSVVEMQSEGGAAGTVHGALQTGALATTFTASQGLLLMIPNMFKI
                     AGELTPAVFHVAARSLAYQALSIFGDHSDVMSARSCGWAMLCGSSTQEAADFAAISHAA
                     TLESRIPFINFFDGFRTSHEIGKIADITDDTLNGMIKQEWLDSFRERALTPDAPVLRGT
                     AQNPDVYFQGRETVNRFYEATPAIVQNAMDKFAELTGRSYHLVDYTGAPDAERVIILMG
                     SGAEAVEETVEAMMTRENAKVGVLKVRLFRPFPAAELVKALPATVRKIAVLDRTKEPGS
                     QGEPLHQDIIQALFDAQANGTLPFTNGMPKVVGGRYGLSSKEFTPAMVKGVYDNLALDT
                     PKNHFTIGINDDVLGTSLPYDEDYSTEADDVTRAMFFGLGSDGTVGANKDAIKIIGQHT
                     NLYVQGYFVYDSKKSGSSTISHLRFGPRPIKSTYLITKANFLALHQPSLLDLFDFLKNA
                     ANGATFLMNSPHPADKLWDTLPARMQQQILDKNIKLYTIDAFAVARKTGMGGRINMIMQ
                     TCFFKLASVIPADEAIGYIKKAIAKTYAKKGQEVVDKNIAAVDATLENLHQVDTTGKTV
                     NGHAIPPAMSPDAPDYVQNVLGKMMCGEGDSIPVSQMPVDGTFPNGTSQYEKRNLALDL
                     PEWDPTLCIQCGKCTAVCPHAVIRSKFFSPDALANAPEGFECLDAKHPDWKGEKFVIQI
                     SPNDCTGCTLCADVCPAKSKTDPTHKALTMVPAGKIHDKEEANWNFFLSLPDVDRTKVR
                     TDNIRSMQVLRPLFEFSGACAGCGETPYVKMLSQLFGNRLVVANATGCSSIYGGNLPTT
                     PWSHDSEGRGPAWANSLFEDNAEFGLGFRVSLDKQMEHAIELLHEAAGAVGQELVDRIL
                     ANPQKDEADIAQQRENIEELKKKIAGKPEYARLLTLADKLVRKSVWILGGDGWAYDIGY
                     GGLDHILASGRNVKVLVMDTEVYSNTGGQCSKSTPRAAVAKFATTGKPGVKKDLGLMAM
                     TYGNVYVASVALGAKDEHTLKAFVEAEAYDGPALIIAYSHCISHGINMAKGLQQQKAWV
                     DSGRVLLYRYNPDLTRQGKNPLIVEGKGPKGDLRDVLLSENRFKLLAKTNKEGFEKLLE
                     EAQKDVWHRWNLYQSIAGMGADKPAE"
     CDS             complement(4559..4996)
                     /locus_tag="ctg45_3"
                     /transl_table=11
                     /translation="MNKIIIANYRETEPQVISREGNSFAVKPVIREADAGKCAASFVEV
                     EPGRYAYGYHYHEVNEEVFYIIRGHAVVRTPEGEKNLKEGDAIAFPASPEGAHVIRNGS
                     ATEKLVYLDVGTRLTPDVVHFPDTASGMVYSSSGVHHFRES"
     CDS             5120..5440
                     /locus_tag="ctg45_4"
                     /transl_table=11
                     /translation="MTYYNSSCPVETTLQLISSRWKVLILRDLLEGTRRFGELRKSIGP
                     VTQKVLTANLRSMEKDGLLTRKVYAEVPPRVEYTLTELGRSLRPVLASMAEWGSKYQRE
                     NR"
     CDS             complement(5524..7662)
                     /locus_tag="ctg45_5"
                     /transl_table=11
                     /translation="MRMRCLFFPLCSAIALTSFVQAQSLERHPLYEPALVSAGTPGDAG
                     NLFAGAKVTASGHYGSDRPELAVDGQTNNAGKYWGCEGIPVWLQIDMGKPRTLSSLHVW
                     PYWEGGRIYKYKIEGSEDGKNWKMLADQSSNSIAATPEGVPFKFNPQTVRYVKITFLGN
                     SAGNEKGGHLVEIKGYGPDAALSLQVAAVKDYDRIPYNGAPGQEMLQDAVRLFGWRGER
                     AGGQIAVWSSQAQPQLSASCAGVKNAAGQIIPVRTAMIRYTRGGNRLISDIIGSENSCD
                     LQAGGVRPVWVEVNIPPSAKPGVYKGKVVVSAESGFPVSVLVILEVAPESLPAPAHWQV
                     HLDLWQHPQAVARWHDVEPWSPEHFALMKPVMKRLADAGQKAITCSLIDEAWNAQTYDW
                     FPPMIEWVKGKNGTMRWNYANFDKWVSFMMNEVGVKGQISCYTMIPWNMKIRYLDEATG
                     KYKFLDLKPNDPSYEAIWGPFLTDFRKHVKSRGWLGKTCIGLDERPDAMVRAAKNVLDK
                     YAPEFKIVSAVNRPTAMTRDVYDVSPVIDHAGTVTGDLLAQRKKEGKKTTFYVCVHPKK
                     PNTFTISPLAEAEWLPLFAAANHLDGFLRWAYNSWNRNPFEKTDFGNWPAGDCYLVYPG
                     NLSSLRFEKLRDGLEEFEKVNILRARAAKNPKAKAAVARMDEELSKLFTVEKSRGNSHE
                     EDVRKAREIIRKTTEISR"
     CDS             complement(7710..8477)
                     /locus_tag="ctg45_6"
                     /transl_table=11
                     /translation="VLAKRIIPCLDVTDGRVVKGTNFINLRDAGDPVECARAYDAQQAD
                     ELVFLDITASSDGRATMADVVRRTAACCFMPLTVGGGIRSVKDMREMLLAGADKVSLNT
                     AAINRPELINEGAAAFGSQCIVVAIDAKRQASGKWGVSTHGGRKFVGLDAVEWAVEAER
                     RGAGEILLTSMDADGAKTGYDIELTRAVSSAVRIPVIASGGAGNLDHMVDVLVEGKADA
                     VLAASIFHFGEYTVPEAKAYFASRGIPVRPLAE"
     CDS             8537..8737
                     /locus_tag="ctg45_7"
                     /transl_table=11
                     /translation="MPFDKHVPFLTKALFGSASIPHIHGKRNLLKFINITIPLTFRPAL
                     PRHEETQCGICPFPARMHKTA"
     CDS             8791..10539
                     /locus_tag="ctg45_8"
                     /transl_table=11
                     /translation="MTTTRSGFTKLAAVCIAILLGAVVWELGWPLTRAEHEWSRLIAAV
                     ATLGHLTGILGSYFRKEINRPSLRLLIFQIISCLMIFLLIAREQQEAGYMRFTELSRLM
                     ITAGLIAIPTLMSLTRIFEWLVGKQKKGRPLMAPAMQFVASLGVVILAGTGLLLLPNST
                     YPGITLSFTDALFTSTSAVCVTGLNAVDFAHTFTPLGEMFTLALIQIGGFGIMTFAYFV
                     AMVAGQGFSLRDRVLLTDLLDEGNLGAVVSFITTIVVSTLFIELCGAVLLYFSWEGKDI
                     NLMGEPLWWHSLFHSVSAFCNAGFSTFPMNLMEPGIRLCYSGQAVIMALIVCGGLGFGI
                     YKEINSRLANRFFSKHRRLHMQWTPYFKLVMISTGILLAGGALAIFAVSSPHAAEPLGE
                     HLWICLFDSVTARTAGFNISDYGRYLPAASLIMCGLMMVGGSPGGTAGGMRTTTCAIAG
                     AEILRILRGRDHVEFFRRRIDQRTVARCVITVVVSCAWIGCFTVLICALEPSMSSLDIF
                     FENCSAFATVGVSRGITPDLSGPSKYLLIVNMLSGRVGLFAFLIALAGTPTPRHYRYPS
                     VKIPLT"
     CDS             10550..11254
                     /locus_tag="ctg45_9"
                     /transl_table=11
                     /translation="MRYTVIGLGQFGQELCTELSARNIEVVAVASTDEELEQIKDLVTY
                     AVVTDYTNPAALRELELDDQSAVIVAIGDSFEENLLVVTHLQKMGVRYIYARVMSPVHE
                     HILSQMNVYALINLSRVASKQLASQLESPEFLRVSPMDENHSIVEIAVPRIWVGKRLRD
                     VGLRTEHHLNLLTIRRGEAQTPQGRREILSIPRIPVIGTPSPDLVFEDHDILVLFGKET
                     NLIEFAQLSKGL"
     CDS             complement(11347..13701)
                     /locus_tag="ctg45_10"
                     /transl_table=11
                     /translation="GLGIMDPRERPADAAQKADQAHAQWKEEDSDFLSLLKLWKAAWQF
                     REGRRWRKNQLRKWCGKNFLNFNRMMEWFNLWEDLSRLVRETLKCRISPLEEETERQAS
                     FAMIHRSILAGVPRQFGLWDADNREYRGAGGRSFGIFPGSGLFRRKKRSEWVMGVELVD
                     TTRLWMRRASILEPEWVELVAPHLCESHYSGARWDREQGAVYAVERVVCGGLRIIDNRR
                     VHYGRINPAHAREIMIREGLLGGGFRTKPACIRHLETLREEVRQIELKLRRPDQVWCEE
                     GVFEFFNRLVPPDCCTARAFLRWAAGMEKKNPEALHVPPQEAMYEFWGKDLLDGFPDEI
                     TCKGAEYAVYYQNDPGAEDDGVTLGVHIDQLPDIPEWLPEWGVPGHLAQRAECLLRSLP
                     KDLRVFLQPISQKAAYFAELRHGLEPDGPLAGKLAEFVEVETGKFCAPSFFDMNRLPAE
                     LVTKIWVCDDEGEELAMGTDVAELNNRLGKKLSRRFQETAEDIVSVTGMKEWSCGDLEY
                     TVDVAGRPGYVALVDEGASVGVRVFEDELDAAESHREGCLRFMRLRQTDQLNHLRRKFP
                     LKLEGKLSLHMLGREPSTNAEDLVDVAAEIAMGRPLPRTAEQFAAAEMNLRQNLFDAAH
                     NVADIWELVAGTEHAVRDFTALQKGVRHTERITADLQRQLDWLLRPRFLWAHGAERLPD
                     LKRYMQGIAERIRRIGQQPLARELERLDLFERVYFPWHQVLKEHAGDLRWMQYGYLLEE
                     YRLAVFAPAISVKGRVSEKRLVASFEALSSQ"
ORIGIN
        1 tgtttgtctt cctggaaatc ggctttcaat ccggcgggag tggtggtcac gtcaaatctt
       61 gcgccgtagg ggtcaattcc cagctcacgg attttggcga gcttgtcgcg gcgcacggca
      121 ataagttcgg attccgtcgt ggtcggatgt gcctgctgtt gttcggacat agtgcgggga
      181 ttctaaaggc tcgcttccgt tttggctagc gcattgtcag gcagagggga catttttggc
      241 ggccggtttt gacccgaagg ttcctccccc cctttttcgg aagccggatg ccggaacatg
      301 ccccagtatt tcagccgttt tgcaaaaagc ctgaacagaa ccacataaag cacgatattc
      361 aaaggaattg aaacaaaact ggtcttatta ttaaaaaatg gccggcaaat ccccacatac
      421 gcataattgc ttttaccttt ggcaccagac atgttataaa tgtttccgtt aagacgcacc
      481 ttatttatca attatatact atccgtgcag acttatgagt gatcagacaa ccgtaactta
      541 cagcacgatt gacgctaacg aagccgtagc ctccgtagcc tatcgttttt ctgaagtcat
      601 tgccatttac cccattacac catcttctcc gatgggtgaa tcagctgaaa gctgggccgc
      661 tgtcaacagg aagaatctat ggggcaccgt tccctccgtg gtggaaatgc agagtgaagg
      721 cggcgcggca ggcaccgttc acggcgccct ccagaccgga gcgcttgcaa ctacgttcac
      781 cgcatcccaa gggctcctgc tgatgatccc gaacatgttc aaaatcgcag gggaactgac
      841 tcccgccgtg ttccacgtag ccgcccggtc cctggcttac caggcccttt ccatttttgg
      901 cgaccacagc gacgtgatga gcgcccgctc ctgcggatgg gccatgctgt gcggctcctc
      961 cactcaggaa gcggcggact tcgccgctat ttcccacgcc gctacactgg aatcccgcat
     1021 tcctttcatc aatttctttg acgggttccg cacgtcccac gaaatcggca agattgcaga
     1081 catcacggac gacaccctga acggcatgat taaacaggaa tggctggatt ccttccggga
     1141 acgagccctg acccctgatg ctcccgttct gcgcggcact gcccaaaacc cggacgttta
     1201 tttccagggg cgtgaaacgg tcaaccgttt ctatgaagcc actccggcta ttgtccagaa
     1261 cgccatggac aagttcgcgg aacttaccgg ccgttcctac catctggtgg attacaccgg
     1321 cgctccggac gccgaacgcg tcattatcct gatgggatcc ggcgctgaag ctgtggaaga
     1381 aacggtagaa gccatgatga cccgggaaaa cgccaaggta ggcgtgctga aggtgcgcct
     1441 gttccgcccc ttccccgccg ccgaactcgt caaggccctc cccgctacgg tcaggaaaat
     1501 cgccgtgctg gaccgcacca aggaacccgg ctcccaggga gaaccgctcc accaggacat
     1561 catccaggcc ctcttcgacg cccaggccaa cggcacgctg cccttcacca acggcatgcc
     1621 caaggtggta ggcggacgct acggcctctc ctccaaggaa ttcacccccg ccatggtcaa
     1681 gggcgtctat gacaacctgg ctctggacac tcccaagaat catttcacca tcggcattaa
     1741 cgacgacgta ctgggcacca gcctcccgta tgatgaagat tattccacgg aagcggacga
     1801 cgtgacgcgg gccatgttct tcggcctcgg ctccgacggc accgtgggcg ccaataagga
     1861 tgccatcaag atcatcggcc agcatacgaa cctgtatgtg cagggctatt tcgtgtatga
     1921 ctccaagaaa tcggggtcct ccaccatttc ccacctgcgc ttcggtcccc gtccgatcaa
     1981 atccacatac ctgatcacca aggcaaactt cctggccctg caccagcctt ccctgctgga
     2041 tttgttcgac ttcctgaaga atgccgccaa cggcgccact ttcctgatga acagcccgca
     2101 cccggcggac aagctctggg acacgctgcc cgcccgcatg cagcagcaga ttctggacaa
     2161 gaacatcaag ctctacacga ttgacgcttt tgccgtggcc cgcaaaacgg gcatgggcgg
     2221 ccgcatcaat atgattatgc agacctgctt cttcaagctg gccagcgtga ttcccgcgga
     2281 tgaagccatc ggctacatca agaaggccat tgccaaaacc tacgccaaga agggccagga
     2341 agtggtggac aaaaacatcg ccgccgtgga cgccacgctg gaaaacctgc accaggtgga
     2401 cacaaccgga aaaactgtaa acggacacgc cattccgccc gccatgtccc cggacgctcc
     2461 ggactacgta caaaacgtcc ttggcaagat gatgtgcggt gaaggcgaca gcatcccggt
     2521 cagccaaatg cccgtggacg gcacattccc gaacggaacg tcccagtacg aaaaacgcaa
     2581 tctggccctg gatctgccgg aatgggatcc gaccctctgc atccagtgcg gcaagtgtac
     2641 cgccgtctgc ccgcacgcgg ttatccgcag caaattcttc tctcctgatg ctcttgcaaa
     2701 cgctccggaa gggtttgaat gcctggatgc caagcatccg gactggaagg gagagaaatt
     2761 cgtcatccag atttccccga acgactgtac gggctgtacg ctctgcgcgg acgtctgccc
     2821 ggccaagagc aagacggacc cgacgcacaa ggccctgacc atggtcccgg ccgggaagat
     2881 tcacgacaag gaagaagcca attggaattt cttcctgagc cttccggacg tggaccgcac
     2941 caaggtaaga acggacaaca tccgctccat gcaggtgctg cgcccgctgt tcgaattctc
     3001 cggcgcctgt gccggctgcg gtgaaacccc gtatgtaaaa atgctctccc agctcttcgg
     3061 caaccgcctg gtggtcgcca atgctacggg ctgctcctcc atttacggcg gcaacctgcc
     3121 caccaccccg tggtcccatg actctgaagg gcgcggcccc gcctgggcca actccctgtt
     3181 tgaagacaac gccgaattcg gtcttggctt ccgcgtctct ctggacaagc agatggaaca
     3241 cgccattgag cttcttcatg aagctgccgg tgccgtgggc caggaactgg tggatcggat
     3301 actggctaat ccgcagaagg atgaagcaga catcgcccag cagcgtgaaa acattgaaga
     3361 actcaagaag aaaatcgccg gcaagccgga atacgcgcgc ctcctgaccc ttgcggataa
     3421 acttgtccgc aagagcgtgt ggattctggg cggcgacggc tgggcctacg acatcggcta
     3481 cggcggcctg gaccacattc tggccagcgg ccggaacgtg aaggtgctgg tcatggatac
     3541 ggaagtatac tccaacaccg gcggccagtg ctccaaatcc accccgcgcg ccgcagtagc
     3601 caaattcgcc acgaccggca agcccggagt gaaaaaggat ctgggcctca tggccatgac
     3661 ttacggcaac gtgtacgtgg cctccgtcgc tctcggcgcc aaggacgaac acacgctgaa
     3721 agcctttgtg gaagcggaag cctatgacgg cccggctctc atcatcgcct actcccactg
     3781 catctcccac ggcatcaata tggccaaggg cctgcagcag cagaaggcat gggtggattc
     3841 cggccgagtc ctgctttacc gctataatcc ggatctgacc cgccagggca agaatccgct
     3901 gattgtggaa ggcaaaggcc cgaaaggcga tctgcgcgat gtgctgctca gcgaaaaccg
     3961 cttcaagctt ctggcgaaga ccaataagga aggattcgaa aaactccttg aagaagccca
     4021 gaaggatgtc tggcaccgct ggaacctgta ccaaagcatt gccggcatgg gtgccgacaa
     4081 acctgcggaa taaggtacag gccgcttaat ttcaacgccc ctgtccggct tatccggcag
     4141 gggcgttttt tactgccgga tttcatgaaa aacaaaccat gaatatttcg gggaggggac
     4201 tgcctttccg ccccgccata cagccacgca agcaggcttc ctgcgccagt actttccctt
     4261 cctgaaaacc ggagaattca tccttccccc gcagcacaaa aaaggggcac accttgctgc
     4321 aaggccgggt tttaatatat ctcaccttat acgggttaat ttccgcatgg aggttttgaa
     4381 ggccttcaag gaaccgcagc ctttgctgcc agccatgtcc aaggtaaaga cgtgcatctc
     4441 atgcggccaa gggaatactg ttttctcaca ccttcctccc cataggagcg cggcccgctt
     4501 tcctgcggac cgcgccggtg gaaaaaccgg aaaaaggctt taaaacaggg atgctgcttc
     4561 aagattcccg aaaatggtgc acaccggagg aggaatatac cattccggat gccgtatccg
     4621 ggaagtgcac cacatcagga gtcaggcgag tgcccacatc cagatagacc agcttctccg
     4681 tagcggatcc gttgcggata acatgcgccc cctccgggct ggcggggaat gcaatcgcat
     4741 ccccctcttt taaattcttt tcaccctcag gcgtacgcac aacggcatgg cccctgatga
     4801 tgtaaaatac ctcttcattc acttcatgat aatggtagcc ataggcgtac cgccccggct
     4861 ccacttccac gaaactggcc gcacattttc cggcatccgc ttcccgaatg acgggcttta
     4921 ccgcaaagga attgccctcc cggctgataa cctgaggttc cgtctccctg taattggcaa
     4981 tgatgatctt gttcatggca ttatctgttc tgcttgccgt aacggcaagt acctattaaa
     5041 ataggcggca acattctttc tgtaaagtag gcagaaaata gtaacctgaa ttcctgaaag
     5101 aaaccattgc gtaaactaaa tgacttacta caattcatca tgccctgttg aaactactct
     5161 ccaactgatt tcctcccgct ggaaagtgct catcctccgc gatctgctcg aaggcacccg
     5221 gcggtttgga gaactccgca aatccattgg acctgtgacg cagaaagttc tgaccgcgaa
     5281 cctgcgttct atggaaaagg acggcctgct tacgcgaaag gtgtatgcgg aagtacctcc
     5341 gcgcgtggaa tatactctta cggaactggg gcgcagtctg cgtcccgtcc tggcctccat
     5401 ggcggaatgg ggatcgaaat accaaagaga aaaccgctga tcctcccctc cctttccgga
     5461 gcttaaccga acctccggaa agacatggaa atacagcggt tttccttttt cccgcaagaa
     5521 aggtcagcgg gaaatttccg tcgttttacg gataatttca cgggctttcc gcacgtcttc
     5581 ctcatgggaa ttcccgcggc ttttttccac ggtaaagagc ttggaaagct cttcatccat
     5641 gcgggctacg gcagctttcg ccttaggatt ttttgcggca cgagcgcgca ggatattgac
     5701 cttttcaaat tcctccagtc cgtcccggag tttttcaaac cgcagagaac tgagattgcc
     5761 gggataaaca aggtagcagt ctcccgcggg ccagttcccg aaatccgtct tttcaaacgg
     5821 attgcggttc caggaattat aagcccatct caaaaagccg tccaaatgat tggcggcggc
     5881 aaagagggga agccattccg cctccgccag cggggaaata gtgaaggtgt tgggcttttt
     5941 gggatggaca cagacgtaga acgtcgtctt ttttccctcc tttttgcgct gcgccagcag
     6001 atcgcccgta accgtgcctg catggtcaat tacaggagag acgtcataaa cgtcccgggt
     6061 catggccgta ggccgattga cggcggaaac gattttgaat tccggggcat acttgtccag
     6121 cacattcttg gccgccctga ccatagcgtc cggccgttca tccagcccga tgcaggtttt
     6181 gcccagccag cccctgctct tgacgtgttt gcgaaaatcc gtcaggaaag gcccccagat
     6241 agcttcatag gagggatcgt tcggcttaag atccagaaat ttgtactttc cggtcgcctc
     6301 atccagataa cggattttca tgttccaggg aatcatggta tagcaggata tctgtccctt
     6361 gacgcccacc tcgttcatca tgaaggaaac ccacttgtca aaattggcgt aattccagcg
     6421 catggttccg tttttgccct tgacccattc aatcatgggc gggaaccagt cataagtctg
     6481 ggcattccag gcttcatcaa tcagggagca tgtaatggcc ttttgcccgg catccgccag
     6541 ccttttcatc accggcttca tcagcgcgaa atgctccgga gaccacggtt ccacatcatg
     6601 ccagcgggcc acggcctgcg gatgctgcca caagtccaga tgaacttgcc aatgcgcggg
     6661 agcagggagg gattccggcg ccacctccag aattaccagc acactgacgg gaaaaccgct
     6721 ttctgcggaa actaccactt ttcctttgta cacgccgggt ttggcagacg ggggaatatt
     6781 gacctccacc cataccggac gcacgcctcc ggcttgcaaa tcgcagctgt tttcgctgcc
     6841 gatgatatct gaaatcagcc tgttgccccc cctggtgtag cgtatcatgg cagtccggac
     6901 aggaataatc tgtccggcag cgttttttac cccggcgcag gaggccgata actggggctg
     6961 cgcctgggaa gaccagacgg caatctgccc gccggcgcgt tcgcctctcc agccgaacag
     7021 acgcacggca tcctgaagca tttcctgccc gggagcgccg ttgtaaggaa tacggtcata
     7081 atccttcacc gctgcaacct gcaggctcag ggcggcatcg ggtccgtacc ctttgatttc
     7141 caccagatgc ccccccttct cattgccggc gctattgccc aaaaaagtga ttttaacgta
     7201 acggaccgtc tgcggattga atttgaaggg aacgccttcc ggagtggcgg caatgctgtt
     7261 ggaagactga tccgccaaca ttttccagtt ctttccgtct tcggaacctt ctattttata
     7321 tttgtaaatg cgccctccct cccaataggg ccatacatgc agggaggaaa gcgtccgagg
     7381 ctttcccata tctatctgga gccagacggg aatgccctcg caaccccagt atttgccggc
     7441 gttattcgtc tgcccgtcca cggccagttc cggacggtca ctgccgtaat gaccggaagc
     7501 ggttactttg gctccggcaa ataaattacc tgcatcaccc ggagttcctg cggaaacaag
     7561 ggcgggttca tacaggggat gcctctccag ggactgggct tggacaaaag acgttaaggc
     7621 aatagcggaa cacagaggaa aaaaaagaca gcgcatacgc atattacgca ccggaatttc
     7681 attttctctc aaaagaaaag ctgtttccgc tattccgcca aaggacgcac gggtattcct
     7741 ctggaagcaa agtaagcctt ggcttccggc accgtgtatt ccccaaaatg gaaaatggaa
     7801 gccgccagca cggcatccgc cttcccttcc accagcacgt ccaccatgtg atccaaatta
     7861 cccgcacccc cgctggcgat taccggaatg cgcaccgcac tgcttacggc gcgggtcaat
     7921 tcaatatcat aacccgtttt ggctccgtcc gcatccatgc tggtcaacaa gatttccccg
     7981 gctccgcggc gttccgcctc cacagcccat tccacggcat ccagccccac gaatttccgg
     8041 cctccatggg tggaaacgcc ccacttgccg gaagcctggc gcttggcgtc aatagcgacg
     8101 acgatgcact ggctgccaaa agccgccgca ccttcattaa tcagctccgg cctattgatg
     8161 gccgccgtat tcagggaaac cttgtccgca cccgccagaa gcatttcgcg catgtccttt
     8221 acggaacgga tgccgccgcc taccgtcagc ggcatgaagc agcatgccgc cgtgcggcgc
     8281 accacgtccg ccatggtggc acggccatcg gaagaagcgg taatatccag aaaaacaagt
     8341 tcatccgcct gctgggcatc atacgccctg gcacattcta caggatcccc ggcatctctc
     8401 agattaatga aattggtccc cttgacgacc ctgccgtccg ttacgtccag acacggaatg
     8461 attcttttag ccagcacggc cctatcaagc catcaccgcc gccaaaggaa aagcctaaaa
     8521 tacggcttgc cgcgggatgc cttttgataa acatgttccc tttttgacca aggccctctt
     8581 cggcagcgct tccatcccgc atatccacgg taagagaaat ttactgaaat tcatcaatat
     8641 cactattcca ctcactttcc ggccggccct gccccgccat gaagaaacgc agtgcggcat
     8701 ctgccccttt cccgcccgca tgcataaaac ggcctaagag cttttctttc catgtccagg
     8761 tggtagagtc cgcataaggt atttccattc atgaccacta cacgctcggg attcaccaaa
     8821 cttgcagccg tctgcattgc cattcttctg ggggcggtgg tctgggagct aggctggccc
     8881 ttgacgcggg cggaacatga gtggtcgcgg ctgattgcag ccgttgccac gctgggccac
     8941 ctgacgggca ttctgggttc ctatttccgg aaggaaatca accgcccttc cctgaggctc
     9001 ctgattttcc aaatcatcag ctgcctcatg atttttctcc tgattgccag ggaacaacag
     9061 gaagcgggat acatgaggtt cacggagctt tcccgcctga tgattacggc cgggctgatt
     9121 gccatcccca cgctgatgtc cctgaccagg atttttgaat ggctggtggg caagcaaaaa
     9181 aaaggccggc ctcttatggc ccccgccatg cagtttgtag cttctctggg agtagtcatc
     9241 ctggcaggca ccggattgct tctgctgcct aattccacat atccgggtat tacactcagt
     9301 tttacggatg ccctgttcac cagcaccagc gcagtatgcg tcaccggtct gaacgccgtg
     9361 gattttgccc atactttcac cccgctggga gaaatgttca cgcttgccct tatccagatt
     9421 ggcggattcg gcatcatgac gttcgcctac ttcgtagcca tggtggcagg ccagggtttt
     9481 tccctgaggg accgcgtgct gctgacggat ctgcttgatg aaggcaacct gggggccgtc
     9541 gtctccttta ttaccactat tgtggtcagt acgctgttca tcgaactgtg cggcgccgtc
     9601 cttctttatt tctcctggga agggaaggac atcaacctga tgggggagcc tttgtggtgg
     9661 cattccctgt ttcactccgt ttccgccttt tgtaatgctg gtttttcaac tttcccgatg
     9721 aatttgatgg agccgggcat ccgcctgtgc tacagcgggc aggcggtcat catggcgctg
     9781 atcgtatgcg gcggcctggg attcggcatt tataaggaaa tcaattcacg cctggcaaac
     9841 cgcttttttt ccaaacaccg ccgcctgcac atgcagtgga ccccttattt caaactggtg
     9901 atgatctcca cggggatttt gctggcggga ggcgccctgg ccatctttgc cgtttcctct
     9961 ccccatgccg cggaaccgtt gggggaacac ctctggattt gccttttcga cagcgtcacg
    10021 gcacgcacgg cgggattcaa tatcagcgac tacggccgct atctgcccgc agccagcctc
    10081 attatgtgcg gtctgatgat ggtgggaggc agccccggcg gcacggcagg cggcatgaga
    10141 accactacct gcgccattgc aggtgcggaa atcctgcgca tcctacgcgg cagggatcat
    10201 gtggaattct tccgccgccg catcgaccag cgcaccgtgg cgcgctgcgt aattaccgtg
    10261 gtggtctcct gcgcctggat cggctgcttt accgtcctga tttgcgcctt ggagccctcc
    10321 atgagctctc tggatatctt ctttgaaaac tgcagcgctt ttgctacggt aggcgtgtcg
    10381 cggggcatta ctccagattt aagcggtcct tccaaatacc ttcttatcgt caacatgctc
    10441 tccggccgcg tggggctctt cgcttttctc attgcgctgg ccggcacccc tactccgagg
    10501 cattaccgct atccatccgt caaaatcccg ttaacctgaa tataccatta tgagatacac
    10561 cgttatcggc ctgggccagt ttgggcagga actctgcaca gaactttccg cccgtaatat
    10621 tgaagtagta gccgttgcct ccacggatga agaattggag caaatcaagg atctggtgac
    10681 ttatgccgtg gtgacggatt acactaatcc ggccgctttg cgtgagttgg aactggacga
    10741 ccagtccgcc gtcattgtcg ccatcggaga cagttttgaa gaaaaccttc tcgtcgtcac
    10801 gcaccttcag aaaatgggcg tccgctacat ctacgcccgc gtcatgagtc cggtgcacga
    10861 acacatttta agccagatga acgtgtatgc gctcatcaac ttgtcccgcg tggcttccaa
    10921 gcaactcgct agccagttgg aatccccgga attcctgcgc gtctccccca tggacgaaaa
    10981 ccacagcatc gtggaaatag ccgtgccgcg catctgggtg ggcaagcgcc tgcgggatgt
    11041 aggcctgcgc acggaacacc accttaacct gctcaccatc cgccgcgggg aggcccagac
    11101 tccgcagggg cgccgggaaa tcctgtccat accgcgcatt cccgtcattg gcaccccttc
    11161 cccggatctc gtttttgaag accacgacat tctggtcctg ttcggcaaag aaaccaattt
    11221 gattgaattc gcccaattat ccaaaggatt gtaaaccatc ctccgcgagc aggctgaggg
    11281 tatccctctc catttcagaa aaaggcgccg gataagccgc ctgtgcaaac agcctccgtc
    11341 ctggttttac tggcttgaca atgcctcaaa agaagccacc agacgttttt cggagacgcg
    11401 gcccttgacg gagatggcgg gagcgaaaac ggccaggcgg tattcttcca gcaaataacc
    11461 gtattgcatc cagcgcaggt ctccggcatg ttccttcaaa acctgatgcc agggaaaata
    11521 cacgcgttca aagagatcca agcgttccaa ttccctggca aggggttgct ggccgatgcg
    11581 tctgatacgc tccgcaattc cctgcatgta ccgtttcagg tccggcaagc gttccgctcc
    11641 atgcgcccac aggaaacggg ggcgtaacaa ccagtcaagc tggcgctgaa ggtcagccgt
    11701 aatgcgctcc gtatggcgca cacccttttg cagcgccgta aagtccctga cggcatgttc
    11761 cgtacccgcc accagttccc atatatccgc cacgttatgc gccgcgtcaa aaaggttttg
    11821 gcgcagattc atttccgcag cagcgaattg ctccgccgtg cgcggcaaag gacggcccat
    11881 ggctatctcc gcggcaacgt ccaccaggtc ttccgcattg gtagacggct cccgtccgag
    11941 catatgaaga gagagctttc cttccagctt caacggaaat tttctgcgga gatggttaag
    12001 ctgatccgtc tggcgcaggc gcatgaaacg caggcacccc tcccggtggg attccgcagc
    12061 atccagttca tcctcaaaga cacggacgcc cacggatgct ccttcatcca ccagagccac
    12121 ataacccggc cttcccgcca catccaccgt gtattccaaa tctccgcagc tccattcctt
    12181 catgccggtt acggacacga tatcctccgc tgtttcctgg aaccgacggg aaagtttttt
    12241 acccaggcgg ttattcagtt ccgcaacatc cgtgcccatg gcaagctctt ccccttcatc
    12301 atcgcacacc catattttcg taaccagctc cgcaggaaga cggttcatgt caaaaaagga
    12361 gggcgcgcaa aattttcccg tttccacttc cacaaattcc gccagtttcc ccgccagcgg
    12421 cccgtccggt tccaggccat gcctcagttc cgcaaagtaa gcggcctttt ggctgatagg
    12481 ctggagaaag acgcgcaaat ccttgggaag ggaacgcagc aggcattccg cccgctgggc
    12541 cagatggccg ggaacccccc actccggcaa ccattcggga atatccggca actggtcgat
    12601 gtggacgccc agggtcacgc cgtcatcctc cgcgccggga tcattctggt aatacacggc
    12661 atattccgct cctttacagg tgatttcatc cggaaaacca tccagcaggt ctttccccca
    12721 gaattcgtac atagcttcct gtggcggaac atgcagagct tccgggtttt tcttctccat
    12781 accggcggcc caccgcaaaa aagccctggc cgtacagcag tccgggggaa caagcctgtt
    12841 aaagaattca aaaactcctt cctcacacca gacctggtcc ggacggcgca acttcagctc
    12901 tatctgccga acctcttccc ggagtgtttc cagatgcctg atacaggcgg gtttcgtgcg
    12961 gaaaccaccg cccaacaggc cttcgcgtat cattatttcc cgcgcatggg cgggattgat
    13021 acggccatag tgcacacgcc tgttatcaat aatgcgcaag ccgccgcaca cgacgcgttc
    13081 cactgcgtaa acagccccct gctccctgtc ccaccgcgct ccggaatagt gtgattcgca
    13141 cagatggggc gctaccagct ccacccattc cggttccaaa atggaggcgc ggcgcatcca
    13201 caggcgcgtg gtgtccacca actccacgcc cattacccat tcactccttt ttttacggcg
    13261 gaacaggccg gaaccgggaa aaatgccgaa ggaacgtcct ccggcgccgc gatattcccg
    13321 gttgtctgca tcccagaggc cgaactggcg cggaacgccc gccaggatgc tccggtgaat
    13381 catggcaaag gaagcctgcc gctccgtttc ttcttccaaa ggggaaattc tgcatttcag
    13441 tgtttccctg accagccggg aaaggtcctc ccataaattg aaccattcca tcatgcggtt
    13501 gaaattgagg aaatttttcc cgcaccattt ccgaagctgg tttttacgcc agcgccttcc
    13561 ctcccggaat tgccatgcag ccttccataa tttgagcaga gacaggaagt cactatcttc
    13621 ttccttccac tgcgcgtggg cctggtccgc tttctgagcg gcatccgcag ggcgttcacg
    13681 gggatccatg atgcccaggc cgg
//
