LOCUS       c00056_gnlPro..        16504 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HEGDOLKO_56.
ACCESSION   c00056_gnlPro..
VERSION     c00056_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 07:59:41
            Original ID  :: gnl|Prokka|HEGDOLKO_56
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16504
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16504
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3033:6504]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3034..6504
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..16504
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16504
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(134..1366)
                     /locus_tag="ctg56_1"
                     /transl_table=11
                     /translation="MKILLVTRGSQGDVLPYLAIAAELERRGHKVTINLPQIFEETVKP
                     YGFKYVLQQFDDIGGMIDSAAQNSHKFRPFLKWMRNVIDKQFDQLIPLLKEHDILVSTN
                     SEFAVASIAEYCKKPLIRTAYAPFLPGKKIPPAVLPFPKPNPIITPAILWKLMNRMTNF
                     MVKDTINKNRAKYGLAPIRNFGYHAGERSYNYLLFSQHLGNVDPDWTFEWSIGGYCFND
                     TFQYDEKAYEEMISFVDSAQSPIIFFTLGSCSSKDGNRFSKALVDICKKHDYRLIIGSG
                     WAKTGITLQADKHLFLMKQPVPHNLIFPHCDGVIHHGGCGTTHSVGRAGKPQLITPLII
                     DQPYWSYRIHQLGLGPEGVKIAKASEQEIERKVCDLVTNPLYKKNAAHIGEMIQKEGGI
                     KNICDSIERFQ"
     CDS             complement(1400..2611)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg56_2"
                     /sec_met_domain="Radical_SAM (E-value: 6.2e-16, bitscore:
                     49.1, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKRTTSSFRAMSTERKLESIFLFVTGRCNAKCAMCFYAQEMDK
                     KQPDLTFDEIKKISETAGQFNRLWISGGEPTLREDLPEILELFYKNNHIKDVNIPTNGL
                     KPARIVEWVKRFRQNCPDCNINVSLSLDGFGTTHDTQRGVPGNFYKALETLRKIQENFG
                     DDGKVLKNIATVITKYNIDQVEDFMTWVYGRFRTSTHTIEAARGMTRDDGVKILTESTL
                     RKIQDDISPIYSAYADRMVADTTGLRKPITRFFYLGLIRTLYNVRASNIDHPTPWGMDC
                     TAGETTLVIDYDGRFRACELRKPLGNIKEYGCDISKVMNSEAMKQEIAAIGHGYKANCW
                     CTHGCWITSSVIFNPRKMIRSVYKGYRETKRLNHPLAINEQKLQTMEAKYHLDIERLRQ
                     LNIR"
     CDS             2887..2997
                     /locus_tag="ctg56_3"
                     /transl_table=11
                     /translation="MKKPRCKYTDFSIPVKGYNAKLCFTTYNKNKKAPFF"
     CDS             complement(3034..3789)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg56_4"
                     /sec_met_domain="Fer2_3 (E-value: 1.6e-26, bitscore: 82.5,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 3.1e-12, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.3e-06, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDISVTLKVWRQRGPKEKGQFETYKIEKINQSVSFLEMLDILN
                     EQLVNEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFHDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFTSVNTGGVPDANAIPIPKKDADLAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFICAKLQD"
     CDS             complement(3820..5763)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 194.5; E-value:
                     1.1e-59)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg56_5"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.5e-60, bitscore:
                     194.5, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.2e-38,
                     bitscore: 122.0, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEINSKIPQGPLAEKWTNYKNHQKLVNPANKRRLDVIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRQIGLGKVKMYTRHEMLDVVKVDGRARGIIARNLITGKIERYAAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDFQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNSTGLAVFLDFSDAINRLGKEVVKQKYGNLFDMYEEITNDNPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFVEAEKAIKDRIQKLMNVKGKETVDTIHRKLGHI
                     MWEHIGMARDAKGLQEAIQMLKDLKKEFWSNVFIPGNADNLNTELEKALRVADFIEIGT
                     LMAHDALDRAESCGGHFRTEHQTEEGEALRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     EFVVPQTRNYKK"
     CDS             complement(5812..6504)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg56_6"
                     /sec_met_domain="SucD_FumR (E-value: 1.4e-74, bitscore:
                     239.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSISGLFLVLFLLFHLSMNVAAVFSGEAYNMV
                     CSLLGSNWYAVAATLVLAAGVVIHFVYAIILTLQNRKARGNDRYAINARPKGVEWASQN
                     MFVLGLIVILFMLLHFSQFWYKMMFAELIGHHEVALGSAMVSPQDGAAFINYYFQGNAV
                     ITVLYLIWYVALWFHLTHGFWSAIQTIGWNNTIWMNRWECISKIVATVICGLFAIITII
                     FFLNGVGA"
     CDS             6627..8105
                     /locus_tag="ctg56_7"
                     /transl_table=11
                     /translation="MGEVRACAPTHEIMRKEKAFLMNNLYTFAYMRKDLNGARHFSIGI
                     KFTILLFTIAILVLVLFSYRSDKHGNLFWQVEKLIPHHPDSALVLLEKVTDINGLSLRE
                     KARYCLLWTESRDEAGLRHTSDSIISIATDYYRTTRGCYWPPKAWFYRGKVYEDMDQPS
                     LALECYLRALEYEGGNWDYEFWGRLYNQIGRLYAEQELYGKAMSFLRKASAQYQLLNDT
                     AGQGRILEEVKKYEALRDSIGSLSARESIYQITSRYDVRPVREDLYRKELMLSQRGQER
                     YLYAFIIGIILFICFLLYRRWRNTQENALRREEALRRSIASQQQRMREEKEENERQIAL
                     LEKRITKMKEEKDQELMLVSLQLEKQRLEICNESIHNKESKHLLSVAILRKSEVYEKFH
                     DRDAGKIISEDWELLEVLLNKAYDDFTLRLKKLYPVISDTELKACMLTKIGVPANQITR
                     VLKYNSSVLRPRLFRKIFKKEGSTEAFVEFISNF"
     CDS             8215..9438
                     /locus_tag="ctg56_8"
                     /transl_table=11
                     /translation="MKSVKLASILFYLNSVFVVFCFVSCGSSPTEASSLLTADIRGGMD
                     KPGLLGLGDEIKGVTFVPLEVTTDDASLIDGVYDYAVTDRYIYVLPVKEPRIVLFDRQG
                     RFIRTLVKEGQGPGEFRGILPCIQVDERNDRLFLFSNNRVWEYTLEGEFIGQSTHEYSV
                     IYMRHIGKDRFAAISFPFQPFNGGGFGLGLFSRKGDTIAIKNDFYSFLLPHEKSGFTTS
                     IAPAYSDAQNSVLFKTGSNDTVFCISADRISAACVLDLKNSDAEVIRSLDVTDMSNLRI
                     EKKDPKDIFVQDMIEFPGHYYFRLLYNQGYYIASVDKKTGKTLVEKCVMPGSIYELADA
                     NLQHGMQGTRSYRNFPVWGRVIKDELVQVVTPYELNLYKSLRSITIPQELDLKGEEGNP
                     VFVFYSLI"
     CDS             9849..10340
                     /locus_tag="ctg56_9"
                     /transl_table=11
                     /translation="MKKAIMNTMIILFALAMCVGCGQSSEQKEESVPTDVTKAEKQEQV
                     QVEAEDEDTLENGEQVFRVVEVMPKFPGGDAELLKFIAKNVKYPQESQDKGEQGRVICS
                     FVVTKDGTLTNYKVLRGISPALDQEAVRVLQMMPRWTPGTQRGEPVAVKYTVPITFKLQ
                     "
     CDS             10456..10818
                     /locus_tag="ctg56_10"
                     /transl_table=11
                     /translation="MEKLTMQEEEAMRWIWRIGPCFVKDVLAKYEDPKPPYTTLASVIK
                     NLERKKYVKAKRYGNTYEYRPLIEETEYKRTFLGGVVTNYFANSYKEMVSFFAKDQKIS
                     TDDLKDIIDLIEKGKE"
     CDS             10836..12659
                     /locus_tag="ctg56_11"
                     /transl_table=11
                     /translation="MTPEFAYLLKVNVAFVLFYAFYRLFFYKDTFFKLRRAILLAFFGL
                     ALFYPLLNIQDWVRQQEPIADVIYMYSAMLPEATAKADAAASVDWYGWLLGSLGFIYWG
                     IVAFLCGRFLVQLSSILWLAHTSERVVIHETPVYALRKAAGPFSFFRMVFLHPESHSDK
                     ETDEILTHECTHVSQWHSIDVILSEMMCMACWFNPFVWLLKREVRHNLEYLADNTVIQS
                     GYDSKSYQYHLLGLAHHQSVTTLYNSFNVLHLKNRIMMMNKKRSPGIVRTKYLIFIPLV
                     GILMLLSNIEAVARLTVRLANEATVSNAVVTATGILVDETGQPLIGASVVVKGGKEGTI
                     TDRKGAFSLEVPANAILRCSYQGRESQEVLAADMTNNTHLSLSSKSREMNEQVFTVVEK
                     MPSFPGGDAELLKYIATNIKYPKESQDNGEQGRVICSFIVGRDGSVNNPEVLRGVTPLL
                     NEEAVRVINTMPRWNPGMQRGKAVAVKYTVPITFRLKSPVEEMKEETLTVVDVMPQYPG
                     GDRELLKFIAQSIKYPTDAQEAGVQGRVICSFVVDKKGNIVEPKIIRGIDPSLDAEALR
                     VIGMMPRWTPGRQDGKAVRVLYTVPITFRLQ"
     CDS             12716..14578
                     /locus_tag="ctg56_12"
                     /transl_table=11
                     /translation="MNAKCNLVTVLLLCCLIFPGNAQEFNWQDLVNRKQYAAVIAHADS
                     LTLADSSNYEIMNAIGQAYEGMLRYQKAYDYYRLCFSMDMTNLDILNILARTATNLGRA
                     EDAERYFHQVLSADSSNFYANYQLARLYFQLGEYEKAVDAYEKLQAQNEDNTVLYRAIG
                     DCYTRMEQYPSATTAYFQAYNLNRENAGLAVALVNSLYRMGASSPDYISEGIAICDTAL
                     FYNPGNRQLLRSKGLGLYIVKQFVQADSVYSSLLADGDSTYLTLKYGGASKYYAGLYMP
                     SVDILDMAYEQDTTSVEVCLLLGSALGKTYDRKRAYDLFDRAEKGLEPNRFLVNQLLAF
                     RAETYQKDGRYKEASRLYYEAWKKNPERLDFLAAISHMYSEIDVSKFQSEEDRQRGLFI
                     LVLYMNESLKKKADERTMVFSRALLQSFYEDMFFRNVAEETMIDPDGKKSKISIVDLRN
                     LINQLPEESEMVMEIRAMSARSSGKIEEAARLLYRAWKVKGTRVELLREIANLYSHPDI
                     SGFKNAEELQRGVFAQVTYAKELLKNESDLSNLTFTRPFLESLNSDMSKRGITEQTMLA
                     PDNRKSQLSIDELQSLIQQLPETFDEVKEMIRMMNKEKALKSKK"
     CDS             14610..15767
                     /locus_tag="ctg56_13"
                     /transl_table=11
                     /translation="MRKLTTNAVAMLLALVGCMGCGNRSASSVDNLIRVDVMADYPEKE
                     LILQDLMDVEYIALETTDDFITKGAVKAIGKDIMLVTNRGSDGDILVFDRNGKGLRKIN
                     RLGQSGEEYTQLTGLVLDEDNDEIFVKDNPARKIGVYDLLGNYKRSFKFTDTSYYNYIF
                     NYDRDHLICYKSYPSEKGKRECHLIISKQDGRIIHEIQIPSKGTETPVVTEGEFIITPE
                     FYLTFPDRDKWILVNTSSDTIFHYLPDGNLSPFIVRSPSISSMDTKVFLFPTVITDRYC
                     FMRTMRKEVDFTTFKGFLGEDLVYDKQENALFSYILYNDDFINKEEVSLTSEPRNPEIA
                     ICQTLDAPDLVEAYEKGQLKGKLKEIAANLDEESNPVAMLLKKKK"
ORIGIN
        1 ttgttaacct taaatctaat actattatga aaaaaccacg atgcaaatat acggagttac
       61 tgttatttgt caatggttta agtgctaaat tgtgttttgt aacatgtaat aaaatctaat
      121 aggaacttat gcctcattga aatctttcga tagagtcgca tatattcttt atacctccct
      181 ctttttggat catctcgcct atatgagcgg catttttctt ataaagcgga ttggtgacca
      241 gatcacaaac cttgcgttcg atctcctgct cgctcgcttt cgctatctta accccttccg
      301 gccctaaccc taattggtgg attcgatagg accaataggg ttgatcgata atcaacggag
      361 tgattaattg gggctttccc gcccttccta cgctatgggt cgtgccgcaa cctccatgat
      421 ggataacgcc gtcgcagtgc gggaatatca aattatgcgg aaccggctgc ttcattaaga
      481 ataaatgttt atccgcttgt aaggtgattc ctgtctttgc ccaaccggaa ccgatgatga
      541 gccgataatc atgtttcttg caaatatcga ccaaggcttt gctgaaacgg ttaccatcct
      601 tggaactaca actcccgagg gtaaaaaaga taatagggct ttgagcgctg tcgacgaatg
      661 atatcatttc ctcgtaagcc ttctcatcat attgaaaagt gtcattgaag caatagcctc
      721 cgatcgacca ttcgaacgtc cagtccggat ctacgtttcc taggtgctgg ctgaaaagca
      781 agtaattata tgaacgctct cccgcgtgat agccaaaatt gcggatcgga gcgagtccgt
      841 atttagcccg gttcttgttg atcgtgtctt tgaccatgaa attggtcatc cggttcatca
      901 acttccatag gatggcaggg gtgatgatcg ggttgggttt gggaaatggc aatacggccg
      961 ggggaatctt cttacccggc aagaacgggg cgtaggcggt acgtatcaag ggcttcttgc
     1021 aatactcggc gatacttgcg acagcaaatt ccgagttggt cgatactaaa atatcatgct
     1081 cttttagtag gggaatcaat tgatcgaact gtttatcgat cacgttcctc atccatttaa
     1141 ggaatggccg gaatttatgt gagttttgcg ctgcgctatc gatcatgccg ccgatatcgt
     1201 caaactgctg caatacgtat ttaaatccgt agggtttaac ggtctcctcg aatatttgag
     1261 ggagattgat ggtcacctta tggccacgtc tttccaattc ggccgctatg gccaaataag
     1321 gaaggacgtc gccttgtgag cctctggtta ctaatagtat tttcatgcta cgtttattta
     1381 tgggctatga gggtcttgtt caccggatat tcagttgacg caaacgctcg atgtccagat
     1441 ggtatttggc ttccatcgtt tgtagtttct gctcattgat ggctagggga tgattcaatc
     1501 gtttcgtttc ccggtatcct ttatatacgg agcgaatcat cttacgtgga ttgaaaatga
     1561 cggatgaggt gatccagcag ccgtgcgtac accaacagtt ggctttatac ccatgtccga
     1621 tagcggctat ttcctgtttc atcgcttcgc tattcatcac tttacttata tcgcaaccat
     1681 actcttttat atttccgagc ggtttccgta gctcgcaggc acgaaaacgt ccgtcgtagt
     1741 cgattaccaa ggtagtctct ccggccgtac aatccatccc ccaaggggtc gggtgatcta
     1801 tgttgctggc acgcacatta tataaggtac gtataaggcc gagatagaag aagcgtgtga
     1861 tcggtttcct taagccggtg gtatccgcta ccatccgatc cgcataagca gaatagatag
     1921 gggatatgtc gtcttgtatt ttgcgtagcg ttgactcggt taggattttc acgccatcgt
     1981 cacgggtcat gcctctggcg gcctcaatcg tatgcgtgga ggtgcggaaa cgtccgtata
     2041 cccaagtcat gaagtcttct acctggtcta tattgtattt cgtgataacg gttgctatat
     2101 ttttcaggac cttgccgtcg tctccgaaat tctcctgtat cttacgcagg gtttccaagg
     2161 ccttatagaa gtttcccggt acgcctctct gtgtatcgtg ggtcgtaccg aaaccatcca
     2221 aggaaaggct tacgttaata ttacaatccg ggcagttctg gcggaaccgt tttacccatt
     2281 cgacgatccg ggctggtttt aagccgttcg tagggatgtt cacatctttg atatggttgt
     2341 ttttgtagaa taactccaat atttccggta gatcctcacg cagggtaggc tcacctccgg
     2401 atatccataa tcggttgaat tgcccggcgg tttctgatat cttcttgatt tcatcgaaag
     2461 tgaggtcggg ttgcttctta tccatttctt gggcatagaa acacatcgcg catttggcgt
     2521 tgcatcggcc tgttacgaaa aggaagatcg actcgagttt tctttccgtg ctcattgccc
     2581 tgaaagaact ggtggttcgt tttttgtcca ttttattttt gttttaccat ttgtcttatc
     2641 tggcgcatga ttttttcctt gtgtttgatc aacacccgga gaaaataaca taagaagcca
     2701 aataaaatac ttattagcat atactatatg atctttaaag gcaaagatcg acgataaaat
     2761 gacgctaaac aatctctatt tgcagtattt tatggtccat gtttaaaagg taggtctata
     2821 aacaattaaa gcctgtctca cgacaagccc taaccaaact ttgttaacct taaatctaat
     2881 actattatga aaaaaccacg atgcaaatat acggactttt caattcctgt caagggctat
     2941 aatgctaaat tatgttttac gacatataac aaaaacaaaa aggcgccttt cttttagaga
     3001 aagacgcctt ttccatgata tactaatcaa atattagtct tgtaatttag cgcaaatgaa
     3061 ctcgcggttc aaacgagcga tgttgctaac ggagatattc ttcggacatt ccatctcgca
     3121 agcacgtgtg ttcgtacagt taccgaagcc aagctcatcc attttagcga ccatagcttt
     3181 ggcacggcga gcagcctcga ctttaccttg aggcaacaaa gccagctggc taaccttagc
     3241 ggatacgaat aacatagcgg aaccattctt acaagcggca gcacaagcgc cacaaccgat
     3301 acaagcggca gcgtccatgg ctaagtctgc gtccttcttt gggataggta tcgcattagc
     3361 gtcgggtaca ccacctgtgt tgacagatgt gaaaccaccc gcttggatga ttttgtcgta
     3421 agcgtagcgg tctaccatca agtcgcggat aacagggaaa cctgcggaac gccacggttc
     3481 gatcgtgatc gtctctccat cgtggaaacg acgcatatat aactggcaag tcgtagctcc
     3541 agttgccggt ccgtgcgggt gtccgtttac atacaatgaa cacatgccac agataccctc
     3601 gcggcagtcg tgatcgaata cgatcggttc cttaccctcg ttgaccaact gctcgttcaa
     3661 gatatccaac atttccaaga aagagacact ctgattgatc ttctcaattt tgtatgtctc
     3721 gaactgtcct ttctccttcg gacctctctg acgccaaacc ttaagtgtta cacttatatc
     3781 tttatccatg attctaattt tttctgagat tgatgattat tacttcttgt agttacgtgt
     3841 ttgaggaaca acgaactcat agttcaaatc ctctttcaac atgacaggat ctttgtcctc
     3901 gccttggtac tcccagcaag atacgtacat gaacttatcg tcatgacgca aggcctcacc
     3961 ttcttctgtc tggtgctccg tacggaagtg accaccacaa gactcagcgc ggtccaaagc
     4021 atcgtgtgcc atcaatgtac cgatctcgat aaagtcggct acacgtaatg ctttctctaa
     4081 ctcggtattc aagttgtctg cgttgcctgg gatgaatacg ttgctccaga actctttctt
     4141 caagtctttc agcatctgga tagcttcttg caaacctttt gcgtcgcgtg ccataccgat
     4201 atgttcccac atgatatgac ctagtttgcg gtggatagtg tctacggttt ctttaccctt
     4261 gacgttcatc aatttttgga tacgatcctt gatggccttt tctgcctcga cgaactccgg
     4321 cagatccgtg ctgaagcgag gaacttggat ttggtcggac aaatagttct ggatcgtgta
     4381 tggtaatacg aaataaccat cggccaatcc ctgcatcaaa gcggaagcac ctaaacggtt
     4441 cgctccgtga tcggagaagt ttgcctcacc gatagcgaac agacccggaa tggaggtcat
     4501 caactcatag tcaacccaca atccacccat tgagtagtgc aatgccgggt agatcatcat
     4561 cggagtctcg tatggattat cgttcgtgat ctcttcgtac atatcgaaca agttaccgta
     4621 tttctgctta acgacctctt tacccaagcg attgatcgcg tcggagaaat ccaagaatac
     4681 ggccaagccc gtgctgttca cgccgaaacc tgcgtcgcaa cgctctttag cggcacgaga
     4741 agccacgtcg cgaggaacca agtttccgaa tgccggataa cgacgctcca aataataatc
     4801 acggtctgcc tcgggaatat ctttaccttt cttcgttccg gcctgtagag ctttagcgtc
     4861 ttccagtttc ttcggaaccc agatacggcc gtcgttacgc aaggattcgg acatcaaagt
     4921 caatttagat tggaagtcac ctttcaccgg tacgcaagtc gggtggatct gaaccataca
     4981 aggattagcg aagtaagcgc ctttcttgta gcattgccat gcggcggaac cgttagatgc
     5041 catagcgttg gttgacaaga agaacgtatt aacgtaacca cccgtagcta caactacagc
     5101 gtgagcggcg taacgctcga tcttacctgt aatcaagttg cgggcgatga taccacgagc
     5161 acgaccgtct accttaacta catccaacat ctcatgacga gtgtacatct taaccttacc
     5221 caaaccgatc tgacggctca acgctgaata agcgcctaac aaaagctgct gacccgtctg
     5281 gccacgggcg tagaacgtac gcgatacctg agcgccaccg aatgaacggt tatccaacaa
     5341 accaccatat tcgcgagcga aaggaacgcc ttgagccacg cactggtcga tgattgagtt
     5401 agaaacctca gccaaacgat aaacgttagc ctcacgagca cggtagtcac cacctttgat
     5461 cgtatcgtag aacaaacggt aaacagagtc accatcattc tggtagttct tagcggcgtt
     5521 gataccacct tgagcggcga tagagtgcgc acggcgggga gaatcttgga tacagaagtt
     5581 caatacgttg aatcccatct ctgccaaaga tgcggcagcg gaagctccgg ccaaacctgt
     5641 accgactacg ataacatcca aacgacgctt gttagcgggg ttcaccaatt tctggtgatt
     5701 tttataatta gtccacttct cagccaacgg gccttgaggt attttagaat ttatttcaga
     5761 cataatgatt taatttcaaa agttcttaat tataaaacct gtagcttgca attaagcacc
     5821 tactccgttt aggaagaaga tgatagtaat gatcgcgaaa agtccgcaaa taaccgtagc
     5881 tacgatctta gagatacatt cccaacggtt catccagatc gtattattcc aaccaattgt
     5941 ttggatagcg ctccagaacc cgtgagtcaa gtggaaccac aaagccacgt accagatcaa
     6001 ataaagaacg gtgatcacgg cattaccttg gaagtaatag ttgataaaag cggctccgtc
     6061 ttgtggagat accatagctg accccaatgc tacttcgtga tgaccgatca attcggcgaa
     6121 catcatctta taccagaact ggctgaagtg caacagcatg aacaggataa cgatcaaacc
     6181 caaaacgaac atgttctgag atgcccattc cacgcctttc ggacgagcgt tgatagcgta
     6241 acggtcgtta ccacgtgcct tacggttttg caaggtaaga atgatagcgt acacgaagtg
     6301 gatcacaacg cctgcggcca atacgagagt agctgccaca gcgtaccaat tagagcccaa
     6361 cagcgaacaa accatgttat aagcctctcc ggagaaaacg gccgccacgt tcatcgacag
     6421 gtggaacaat aagaacagaa caagaaagag gcctgatata ctcattatca gcttcttccc
     6481 gatagaagaa ttaagtaacc acataagata ataatttaag ttatttaatt gtatttagaa
     6541 atttctactt aaactatgta attatcacgc aaaggtatgc taaatccata tatcgcgcaa
     6601 acgattaaag aaatatttct gcattaatgg gagaggtcag ggcatgtgcc ccgacacatg
     6661 aaataatgcg gaaggaaaag gctttcctta tgaataattt atatacattt gcctatatgc
     6721 gtaaggattt gaatggggca cggcattttt ctatagggat caagtttacg atcttattgt
     6781 ttacgatcgc aatcttggtt cttgtgcttt tttcgtatag gagcgacaag catggcaacc
     6841 tgttctggca ggtagagaaa ttgattccgc atcatccgga cagcgctttg gtgttattag
     6901 agaaagtgac ggatatcaat ggattatcgc ttcgagagaa agcccgttat tgtctgttat
     6961 ggaccgaatc acgggatgag gcgggattga ggcatacatc ggattccata atctctatcg
     7021 ctacggatta ttataggacg acacgaggct gttactggcc tcccaaagcg tggttttacc
     7081 gggggaaagt ctatgaggat atggatcaac cgtccctagc tttggaatgc tatttacgtg
     7141 cgttggaata tgagggaggg aattgggatt acgaattttg gggacggtta tataaccaga
     7201 taggaaggct gtacgccgag caggaattat atggcaaggc catgtctttt ttgagaaaag
     7261 cgagtgccca atatcagctc ttgaatgata cggccggaca aggccggata ctggaggaag
     7321 tcaagaaata cgaggcgtta cgggattcta tcggatcgct gtcagcgaga gaatcgattt
     7381 atcagatcac ttcccggtat gatgtaaggc cggttcgtga ggacttgtat aggaaagaat
     7441 tgatgctatc gcaaagggga caggagcgtt atctgtacgc atttattatc ggcataatcc
     7501 tatttatttg cttcctcctt tatcggcgat ggagaaatac gcaggaaaac gctcttcgaa
     7561 gggaagaagc cttgcgacgc tcgattgcta gccagcaaca acgtatgcga gaagaaaaag
     7621 aagagaatga acggcaaatc gcccttttgg aaaagagaat tacgaaaatg aaggaagaaa
     7681 aggatcaaga gttgatgttg gtttccttac aattggaaaa acaacggctg gagatttgta
     7741 acgagtcgat tcataataag gagagtaagc atttattatc tgttgcgatc ttgcggaaat
     7801 cggaggtcta tgagaagttt cacgatcggg atgccggcaa gattatctct gaggattggg
     7861 agcttttgga ggttttgttg aataaggctt atgatgactt taccttacgg ctgaaaaagc
     7921 tatatcctgt tatttccgat acggagttga aggcctgtat gctcacgaaa atcggtgttc
     7981 ccgccaacca gatcacacgg gtattgaaat ataatagttc ggtacttcgt cctcgtctat
     8041 tccggaagat ttttaagaaa gaaggttcta cggaggcatt tgtggagttt atatcaaact
     8101 tttgattatt atatatttat agtggtcttg gcaggtttgt tctcattttt gttctcattt
     8161 atcatgtgat ttgtgagata tacgggatat ttttggaggc aaaaaagcat ggttatgaaa
     8221 agtgtaaagt tagcctctat cttgttttat ttaaatagtg tttttgtcgt tttttgtttc
     8281 gtgtcatgcg gttcttcgcc aacggaagcg tcctctcttt taaccgcaga tataagaggg
     8341 gggatggata aaccggggct attgggatta ggcgatgaga tcaagggggt tacttttgtc
     8401 cctttagagg tgaccacgga tgatgcctcg ttgatagacg gagtttatga ttatgccgtg
     8461 acagatcgat atatctatgt gcttcccgta aaagagcccc gtatcgtcct gttcgatcgg
     8521 caagggcgtt ttatccggac gttggtaaaa gaagggcagg ggccgggtga atttagaggt
     8581 attctgccat gtatccaagt ggacgaacgt aatgatcgcc tttttttatt tagtaataat
     8641 cgagtttggg aatatacgtt ggaaggtgaa tttatcggac aatccaccca tgagtattcg
     8701 gtaatctata tgcgtcatat cggaaaggat cgtttcgccg ccatatcatt cccttttcag
     8761 cctttcaacg gaggaggatt cggattaggc ctattttcga ggaaagggga tacgatagcg
     8821 atcaagaatg atttttattc ctttttatta ccccatgaga agagcgggtt cacgacaagt
     8881 atcgcccccg cttattctga tgcgcaaaac tctgtgttgt ttaagaccgg tagtaatgat
     8941 acggtcttct gtatctcggc ggatcgaata agtgcggctt gtgtccttga tctgaaaaac
     9001 tcggatgcgg aagtgattcg ttcgttggat gttacggaca tgagtaattt gcgaattgaa
     9061 aaaaaggacc ccaaggatat ctttgtgcaa gatatgattg agtttccggg acattattat
     9121 ttccgtttat tgtataacca aggctattat atagcctctg tagataaaaa gacgggaaag
     9181 acacttgtgg aaaaatgtgt gatgccgggt tctatctatg aactggcgga tgcgaacctt
     9241 caacatggca tgcagggtac gagaagttat cggaatttcc cggtctgggg gagggtcata
     9301 aaagatgagc tggtacaagt agtgaccccg tatgagctaa acttatataa atcgcttcgc
     9361 tcgatcacga ttccgcagga gttggactta aaaggagagg agggcaatcc ggtttttgtg
     9421 ttttattcgc ttatctgact tcgatatgta tcgctcggtt gtacttcttg taataatcta
     9481 gcgatagaag ctatagtatt catggttact atctatagaa aatctgattt actattgata
     9541 gtaatctgat ttattataga tagtaattgg atcggtaata ggcgtgtatg tataactgct
     9601 tagatatcag ccatatacta atatttacgt gcaaagtggg catattgtgt attttaactg
     9661 ttcggtaaat aatcgtgttc ttttatcttt tctatgcctt tgatggctat tagtgttaat
     9721 taatgtattg tttatattta tattacgagt atttcgtata tttgcgaaac caacgtaata
     9781 tccggatatg cttagaggtt ggtaagtatg tgtaataacg gtataaataa cattaaaacg
     9841 gattgaaaat gaaaaaggcg attatgaaca caatgatcat cctgttcgct ttggcgatgt
     9901 gcgtaggatg cggacagtct tcggaacaaa aagaagaaag tgttccgaca gatgtaacaa
     9961 aggcagaaaa acaagagcaa gtacaggtgg aagcggagga cgaagatacg ctggaaaatg
    10021 gagagcaggt atttagggta gtagaggtga tgccgaagtt tcccggcggt gatgcggagc
    10081 ttttgaaatt tatagccaag aatgtaaagt atccacaaga gagccaagac aaaggagagc
    10141 aagggcgtgt gatttgttcg tttgtggtaa cgaaggatgg aacgcttacg aattacaagg
    10201 tccttagagg aatctccccg gcattagacc aagaggcggt tcgagttttg caaatgatgc
    10261 ctcgttggac accgggcacg caaagaggcg agccggtagc cgtgaaatat acggtgccga
    10321 tcacgtttaa gttgcaataa ttcacgattg caggtcttgt gattcttatt taatgttaat
    10381 taacgtgcct tccgcatgcc gtttacgact atttcgtagc tttgtggata tacattaaat
    10441 aaaaggataa gatttatgga gaagctaacg atgcaggaag aagaggcgat gcgctggatt
    10501 tggcggatcg gtccttgttt tgtgaaagat gtgctggcca aatacgagga cccgaaacct
    10561 ccttatacga cgctcgcttc cgtgatcaag aatctggagc gaaagaagta cgtgaaggcg
    10621 aaacgttatg gaaatacgta tgaataccgt cctttgatag aggaaacgga atataaacgt
    10681 acgttccttg ggggcgtggt aacgaattat ttcgctaact cgtataaaga aatggtttct
    10741 ttctttgcga aagatcagaa aatctctacg gatgatttaa aggatatcat cgatttgatt
    10801 gagaaaggaa aagaataacc taaatcccac ataccatgac accggaattt gcctacttat
    10861 tgaaggtaaa tgtagccttt gtactctttt acgccttcta ccggttgttc ttctataagg
    10921 acacgttctt caagctacgt cgtgcgatct tgctggcgtt ctttggcttg gctctgtttt
    10981 atcctttgct gaacatccaa gattgggtaa ggcaacaaga gcctatagcg gacgtgattt
    11041 atatgtattc cgctatgttg cctgaggcga cggcgaaagc ggatgccgcg gcgtccgtgg
    11101 attggtatgg atggttgttg ggatctttgg ggtttattta ttgggggatc gtagcgttct
    11161 tatgcggacg ttttctcgtg caattaagca gtatcttatg gttggctcat accagtgagc
    11221 gtgttgttat tcatgaaact ccggtttatg cgttgcggaa ggccgccggg ccattctcct
    11281 ttttccgtat ggtcttcttg catccggaga gtcattcgga taaggaaacg gatgagatat
    11341 tgacacatga atgtacgcac gtatcccaat ggcactcgat tgacgtgatc ttgagcgaga
    11401 tgatgtgtat ggcttgctgg tttaatcctt ttgtatggtt attgaagcgt gaggttaggc
    11461 ataatctgga gtatctggcg gataacacgg tgatccagtc tggttacgat agtaagagct
    11521 atcaatacca tttattggga ttggctcatc atcagtccgt tactactttg tataatagtt
    11581 tcaatgtgct gcatctgaag aaccggatta tgatgatgaa caagaagcgg agcccgggta
    11641 tcgtacgtac gaaatatctg atatttattc cattggtagg gatcttgatg ctgttaagta
    11701 atatcgaggc ggtagcccgt ttgactgtcc gtctggcgaa tgaggctacg gtctcgaacg
    11761 ctgtggtgac ggctacgggc attctggttg atgagactgg gcagcctttg atcggggcat
    11821 cagttgtggt gaagggcggt aaagagggga ctatcacgga taggaaaggg gctttctctt
    11881 tggaggtccc tgcgaatgcg attttgcgat gcagctatca aggaagggag tcccaagagg
    11941 tcttggctgc tgatatgaca aataataccc atttgtcctt atcttccaaa tcccgtgaga
    12001 tgaacgagca agtatttacc gtggtagaga agatgcctag ttttccgggt ggggatgcgg
    12061 agttgttgaa atacatagcc acgaatataa agtatccgaa agagagccag gataacgggg
    12121 agcaagggcg tgtaatctgc tcgtttatcg tcgggcgtga tggttctgtc aataatccgg
    12181 aggtgcttcg gggagtgact cctttattga atgaggaggc cgtaagggta ataaacacta
    12241 tgcctcgctg gaatccggga atgcaacgtg gaaaggcggt cgccgtgaaa tatacggtcc
    12301 cgattacgtt ccgtttgaaa agtccggtag aagaaatgaa ggaagagact ttgacggtag
    12361 tggacgtgat gccgcaatat cccggagggg atcgtgaatt attaaagttt atcgctcaaa
    12421 gcataaagta tccgacggat gcgcaggaag cgggagtgca aggtcgtgtg atctgttcgt
    12481 ttgtggtaga taagaaagga aatatcgtgg aacctaaaat catacggggg atagatccct
    12541 ccttggatgc ggaagctttg cgagtcatcg gaatgatgcc ccggtggact cccggtcgtc
    12601 aggacggaaa ggcggtccgc gtcttatata cggtgcctat tactttccgg ttacagtgaa
    12661 ataagaatag aggctatgtt ggtcgcttaa tcagtaatct taaaaatata cagatatgaa
    12721 tgcgaaatgt aatttagtta cagttctgtt actttgttgc cttatttttc ccggaaatgc
    12781 tcaagagttt aattggcaag acttggtgaa ccgtaagcaa tatgcggctg tgatcgctca
    12841 tgctgatagc cttacactag ctgattcttc gaattatgag attatgaacg ctatcgggca
    12901 ggcttatgag ggtatgcttc ggtatcagaa ggcttatgac tattaccgtc tttgcttttc
    12961 tatggatatg acgaacttgg atatcttaaa catcttggct cggacggcga cgaacttagg
    13021 ccgtgcggag gatgccgagc gatattttca tcaggtatta tccgccgata gctcgaactt
    13081 ctacgctaat tatcagttgg cacgtctgta tttccaattg ggggagtatg agaaagcagt
    13141 tgatgcctat gagaaattgc aagctcagaa tgaggataat actgtcttat accgtgcgat
    13201 tggcgattgc tatactcgaa tggaacaata tccttctgct acgaccgctt attttcaggc
    13261 gtataacttg aatcgtgaga atgcggggtt ggcggttgcg ttagtgaatt cattgtatcg
    13321 gatgggggct agtagcccgg attatatatc ggaaggaata gcgatttgcg ataccgcctt
    13381 gttttataat cccgggaatc gtcaattatt gcgtagtaaa ggattggggc tatatatcgt
    13441 gaaacaattt gttcaggcgg attctgtcta ttccagtttg ttggctgatg gtgattccac
    13501 ctaccttacc ttgaaatatg ggggagcctc gaagtattat gccggtctgt atatgccctc
    13561 ggtagatatt ttggatatgg catatgagca ggatacgacc tcggtcgagg tatgcctctt
    13621 attgggttcc gccttgggta agacgtatga ccggaagcgg gcttacgact tatttgaccg
    13681 ggcggaaaag ggattggaac ccaatcgttt cttggtaaat caattattgg ccttccgtgc
    13741 ggagacttac caaaaggatg ggagatacaa ggaagcgtcc cgtctctact atgaggcatg
    13801 gaagaagaat ccggaacgac tggatttcct ggcggcgatc tcgcatatgt atagtgagat
    13861 tgacgtgtct aaattccaga gcgaggagga tcgccagcga gggcttttta tcttggtact
    13921 ttatatgaat gagagtttaa agaaaaaagc ggacgagagg acgatggtgt ttagccgggc
    13981 gcttctgcaa tccttctatg aggatatgtt cttccgtaat gtggcggagg agactatgat
    14041 agacccggat ggaaaaaaga gcaagatttc tatcgtggat ttgcgtaact tgatcaatca
    14101 attgccggag gaatcggaga tggtcatgga gattcgtgcc atgagcgcca gaagctcggg
    14161 taagatagag gaggcggccc gtctgcttta tcgggcgtgg aaggtgaagg gtactcgtgt
    14221 agaattgctt cgtgagatcg cgaacctata tagccatccg gatatctccg gattcaagaa
    14281 tgcggaggag ctacagagag gtgtattcgc tcaagtgact tacgcaaagg aactgttgaa
    14341 aaacgagtcg gatctgagta acctgacttt tacccggcct ttcttggagt cattaaattc
    14401 ggatatgtcc aaacggggta tcacggagca aaccatgctg gctccagata accggaaaag
    14461 ccagctttct atagatgaac tccaatctct gatccaacaa ctgccggaga cattcgatga
    14521 ggtaaaagag atgatacgga tgatgaacaa agagaaagcg ctaaagagca agaaatgaca
    14581 tcgaacgaaa gactttaaac atcatgaaaa tgagaaaatt aactacgaac gcagtggcta
    14641 tgctactcgc tttagtcgga tgtatgggat gtggcaatcg gtccgcttcc tctgtcgata
    14701 accttataag ggttgatgtc atggccgatt atccggaaaa ggaactgata cttcaagacc
    14761 tcatggacgt ggaatacatc gcgttggaaa ccacggatga ttttataact aaaggtgccg
    14821 tgaaagcgat cggaaaggat atcatgctgg tgacgaatcg gggcagtgat ggggatattc
    14881 ttgttttcga tagaaacgga aagggactaa ggaagataaa ccgtttaggg caaagcggtg
    14941 aggaatacac gcaacttaca gggcttgtct tggatgagga taacgatgag atattcgtca
    15001 aggataatcc ggcgagaaaa ataggtgtct atgacttatt gggaaactat aaaaggagtt
    15061 ttaagttcac ggataccagt tattataatt atatatttaa ttatgatcgt gatcatttga
    15121 tttgctataa gagttatcca tcggaaaaag gcaagcggga gtgtcatttg attatttcca
    15181 agcaagatgg ccgtatcatt catgagatcc aaattccctc taaggggact gagactccgg
    15241 ttgtaacaga aggggagttt atcattacgc cggaatttta tcttacgttc ccggatcggg
    15301 ataaatggat acttgtcaat acatcgtctg ataccatatt ccattacttg ccggatggta
    15361 atctgagtcc ttttatcgta agaagccctt ccatatcctc catggatact aaagtatttc
    15421 tttttccaac cgtcatcacc gatcgctact gtttcatgag aaccatgaga aaagaggttg
    15481 actttacgac gtttaaaggt ttccttggtg aagatctggt gtatgataaa caagaaaatg
    15541 ccttattcag ctatattcta tacaatgatg atttcatcaa taaggaagaa gtctctctaa
    15601 catcagagcc aagaaacccc gaaatagcta tctgccaaac tctagatgcc ccggacttag
    15661 ttgaggctta cgagaaaggc cagctaaaag gaaagttgaa ggagatcgcc gcaaacttgg
    15721 atgaagagtc gaatcctgtg gccatgctgc tgaaaaagaa aaagtaatat attgctccgg
    15781 ctgctacctt gctggaaaaa agtaagttga tggctatatt attttttgat aaacacgtac
    15841 atacctgatt cataatacgt aaatcgattt tagagagaaa tgcctattaa ttctagggag
    15901 actgtatcaa atactatcta ttgcccactt atgttccgga aataaaatgt tcctctcctg
    15961 ttgaaatagt tctccgataa cctatacatt ccatagcgaa taagtattta ttcttaaatc
    16021 agcgccgtga actgtataaa ccacgccgtg gaatgtgcag accacgcctt ggtttataca
    16081 gttcacggca tggtttatag aatagatgag atagcgataa actttatata taggtaaaca
    16141 tacgttttat tctagatgaa tccgtttgcg ttttcgagta aaccagctac atttgccgga
    16201 aagaatatct agatgaggaa gttcctttta ttgtggttgg ttgggttgat gttggtgcct
    16261 tctgtgatgg ctgagcggaa aaaggttggc ttggtgctgg gaggcggtgg ggcgaaaggt
    16321 gtcgctcata tcggggtgtt gaaggtattg gaggaggccg gtatcccgat tgattatatt
    16381 gccggaacca gtatgggagc tatcgttggt ggcttgtatt ccgttggcta tactgccgct
    16441 gagatcgata gcatggtacg ttggcaggat tggagcatgt tgctaagtga ccgtgtgaaa
    16501 cgta
//
