LOCUS       c00020_gnlPro..        13794 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FPBEGCCN_20.
ACCESSION   c00020_gnlPro..
VERSION     c00020_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 08:36:26
            Original ID  :: gnl|Prokka|FPBEGCCN_20
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 21606
            Orig. end    :: 35400
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13794
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[31606:35096]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13490
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13794
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13794
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(465..1055)
                     /locus_tag="ctg20_25"
                     /transl_table=11
                     /translation="MSGLANAFLALLPPDQASLPAAGAEARWLADTAVVQSAAIARDNR
                     TVLFGWLNNILVNSNLRDRGLCWQVQQDLYRDLRRRPVKYFRIGLTIRDRGTGREHSCV
                     YVNAAGKGLQGSIVLDAWKNCGHLVTLTQKDREGGKWEEDWREPFVSKAFPEGHSYGME
                     HHLVWPGWARKRPMLVQRIFQSDQQNEAKAAAE"
     CDS             1295..2905
                     /locus_tag="ctg20_26"
                     /transl_table=11
                     /translation="MLTIKNLTKSHAGRTLFRETEMTINWGERVALVGPNGAGKSTLFR
                     MILGEDTPDEGSISMDEYAIVGYLPQEASEPKDETVLEIALGITPEMEQAIHTIRTAEN
                     ANKTDTPEYAEAIDTFNAANGYQLEPKAKKILKGLAFRESDFHRPAREMSGGWIMRAYL
                     AKLLVLEPDLLMLDEPTNHLDLLSLLWLQRYLKNYPGAILMISHDRDFMDELVESVYDI
                     DNEELVEYRGNYSDFLQQKDVRFEQLQAAYRNQQKEIAHIQEFIDRFRSINSKAGQVQS
                     RIKQLEKMKIIQKPVARRKVFKFNFPQPPRSTQKVIELEKVCQSYGDRRVYENLDLLVE
                     RGERTVLVGPNGAGKSTLLKILAGIIPIDSGQRTPGTTTRIGYFSQARTENLNPENTVL
                     EEIMKCSAEIREEEARSILGSFLFRRLDVEKRVSVLSGGEKSRLSLVKFLVDPPNLLLM
                     DEPTTHLDLLSVEALVQALKHYEGTLVFISHDVHFIRSLAQKTLHVNRGTITAYAGGYD
                     YYLEKSGILDDEKGGITAE"
     CDS             2969..3487
                     /locus_tag="ctg20_27"
                     /transl_table=11
                     /translation="MKAFLVPLLYSALLSGASLAFGETAAGTASPAAAAPAEKIPSAES
                     LINQAFSFAINIQQTLAGVQDKESADNAVKTLQDIQKDIRHFLQLQDKLNDAEKEKEDA
                     LIEKMEKRMEMLDNRCRQEGKRLFEARYYGSAALKDILENSDEFSDLVEPDEDGTPPGA
                     LRENEEAGQ"
     CDS             3616..4362
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_28"
                     /sec_met_domain="adh_short_C2 (E-value: 1.6e-75, bitscore:
                     245.1, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKLAGKTAIVTGAGRGIGNAVARRFASEGARVILISRSPSSCGG
                     AAEEINKEFPDSCKAYPCDVADYAAVQETMAAILKDFPQIDILVNNAGITRDSLMLRMK
                     EEDWDAVLDTNLKSAFNTVKALQRVLMKSPAGRIINMSSVIGLVGNIGQANYAASKAGL
                     IGFTKSLAQEFAPRKVTCNAIAPGFISTEMSNSIPDNLKEEIVKKIPLKEQGSVEDIAA
                     LTAFLASDDARYITGQVIACDGGMTM"
     CDS             4743..5591
                     /locus_tag="ctg20_29"
                     /transl_table=11
                     /translation="MGSPAEEPHRKPDEGPQHKVSISPFWISETEIPWELYTAFMENGR
                     PRAKDGQLLEEQPDDELWDSVTQPTAPYTAMNLGMGHGYEHGLPAISMSHHAASKFCEW
                     LSAQTGHYYRLPTEAEWEYACRAGSPGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSKK
                     PNKWGLRDMHGNVAEWVLDSYVPDAYGKRSGLPAKDPLVIIPGAPHIVRGGSWEDDPDS
                     LRSAARRASTPAWSRQDPQNPKSIWYLTDGGMIGFRVVRPMNIPDIMTMHRLWNFSKGE
                     P"
     CDS             5605..5805
                     /locus_tag="ctg20_30"
                     /transl_table=11
                     /translation="MTIALRTEQSSDHAETEHVTREAFWNYFVPGCHEHYLLHIMRVSP
                     SFIPELDAVAVHGSRIVGKHR"
     CDS             5917..6051
                     /locus_tag="ctg20_31"
                     /transl_table=11
                     /translation="MYAAALQVCELQRGSLSGLKGHYVKAAVYHMDEKRAAEFDGIFR"
     CDS             complement(6269..7009)
                     /locus_tag="ctg20_32"
                     /transl_table=11
                     /translation="MKKTLTFLIAMGSFAVSSEAATVFNYYTPGTDNYNSTIHGFYLGL
                     GSSSLAPSDSSSPSSLSGEIRLDSFTLRGAANNLGANVTYGFLVLNGSDNSVIGWSTNT
                     GTTAAGINLTFSFSSLDGSPLLLDAALTYRFLAVSQSVMDLMQDTSKTYLYAAGGTAAP
                     TANTEGDTVTISGGLTAPGIRGHYDAEGAPGDSVVITGANGTNTFSLLSPIFTEIRGEM
                     VPEPATVSLGLLGLAALMMRRRRA"
     CDS             7184..7273
                     /locus_tag="ctg20_33"
                     /transl_table=11
                     /translation="MNYKYNILTLNIFNCLRIPNSLFKHKYIH"
     CDS             complement(7282..7569)
                     /locus_tag="ctg20_34"
                     /transl_table=11
                     /translation="VLILDRSRTIVTDITSRLLAPYPLKVIPDNVRLLSSDVMETESFR
                     VPKSAVWEAKSEYPTMELSNRAVAAVALRLMPAERIRVDNNLFMVSILIK"
     CDS             complement(7579..7761)
                     /locus_tag="ctg20_35"
                     /transl_table=11
                     /translation="MRVPRSPVTTEMVREPSVPSGVSTTGPLYEVLFHNPWSFRSVFRP
                     TPQLTLLFLALNRAV"
     CDS             7838..8011
                     /locus_tag="ctg20_36"
                     /transl_table=11
                     /translation="MDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGLL
                     GLAALMMRRRRA"
     CDS             8443..8676
                     /locus_tag="ctg20_37"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPD
                     EFLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(8710..9525)
                     /locus_tag="ctg20_38"
                     /transl_table=11
                     /translation="MMAFIEPHIHMVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSAD
                     GFRDYFVQLTECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLG
                     IGEIGLNRNTSHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLD
                     PCRVLVDHCEEHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADW
                     GDSDPLALTALACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(9528..9800)
                     /locus_tag="ctg20_39"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             10001..10702
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_40"
                     /sec_met_domain="SucD_FumR (E-value: 1.8e-13, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             10724..12682
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.1e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_41"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.9e-54, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 8.1e-38,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAITGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             12660..13490
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.6; E-value: 9.2)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_42"
                     /sec_met_domain="Fer2_3 (E-value: 1.9e-23, bitscore: 74.1,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 6e-11, bitscore: 34.2,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.2e-06, bitscore: 19.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LPSAATSKDSQYINTQKKDYNMAKTLNLTLKVWRQENREAKGRIE
                     TYAAKDIPVDASFLEMLDIVNEGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPER
                     QVTTCQLHMRKFKDGDTVWIEPFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAP
                     NANNIAVEKVKADAAFDAAACIGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSK
                     RVLAMMKQMEAEGFGNCTNQYECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(13504..13794)
                     /locus_tag="ctg20_43"
                     /transl_table=11
                     /translation="LDRMPSLPGISLIPVINVSLSRRKMGPSLSDGACLGFVRHFQVRF
                     PGLLGAFRCNNFLRCATMRKQLSGILFLVQGNLVMKKLPTADAAGSFYRAS"
ORIGIN
        1 gtaatgccgt gacatggaac aagaaaatct cttgatttct acttgccacc atttacattg
       61 gtgccagcaa acctccgtgg atgcggaggt tccagtagtt aacaaacact gtatttaatt
      121 cgaattatga agaacatcgc tatcctcgcc atcgccggcg ccgcttgcct ggtcgcttct
      181 tgctcccagc agcagcagca acagcaaacc accgctcctg ctcccgctcc ggttgtgcag
      241 gccaagggca agtaagtttg cagcggggtt ttgccctgca acactagcaa attatccaat
      301 taatccgcac tcggtgtacg cactgagtgc gtttttattt gccctgagtc cggattccct
      361 ccgccatttg ccgattcgcc gggattttcc ttaaaaacgg cggataccgc aaaccgccgc
      421 ggcgcagcac cgtgtgccgg ttcctgccgg atcaggcttc ccctttattc agcggccgcc
      481 ttcgcctcat tctgctgatc ggactggaat atccgctgaa ccagcatggg gcgtttcctg
      541 gcccacccgg gccagaccag gtgatgttcc atgccgtagg aatggccctc cggaaaggcc
      601 ttggaaacaa atggttcccg ccagtcctcc tcccatttgc cgccttcccg gtccttctgg
      661 gtcagcgtca ccagatgccc gcagttcttc caggcatcca gaacaatgga gccctgcaat
      721 cccttccccg cggcattgac atacacgcaa ctgtgctccc tgcccgttcc acggtctcga
      781 atcgtcagcc ctatgcggaa atacttcacg gggcggcggc gcaggtcccg gtacaaatcc
      841 tgctggacct gccagcacag ccccctgtcg cgcaggttgg aattgaccag aatattgttc
      901 agccagccaa acagcacagt cctgttgtcc cgggcaatcg ctgcggactg gaccacggcc
      961 gtgtccgcca gccacctggc ctccgctccg gcagcgggaa gagaggcctg atccggcggc
     1021 agcagcgcca ggaaggcatt agccagcccg gacatttgct gctgcacgta aggttgttgt
     1081 atataatcct ccgccggagg agtacagcag gaactccatc cgcacaaaag ggcggcagca
     1141 agcaaaagcc tgaatgtctg cgtggtcggc atggcgcgcc aaggctagca gactacgcgt
     1201 aaaaatccag taaagctttc aaaaatgcct gcctccgccc tgacggctct tgccttcccc
     1261 tttccatccc ggtagaatac atcctctctt caccatgctg acgatcaaaa atctcacaaa
     1321 atcccacgcc ggacggacct tgttcaggga aacggaaatg accattaact ggggggaacg
     1381 ggtggctctg gttggcccca acggagcagg caaatccacc ctgttccgca tgattctggg
     1441 agaagacacg ccggacgaag gctccatcag catggatgaa tacgccatcg tgggctatct
     1501 tccccaggaa gccagcgaac cgaaggatga aaccgttctg gaaatcgccc tgggcatcac
     1561 gccggaaatg gaacaggcca tccacaccat ccggacggcg gaaaacgcca acaaaacgga
     1621 tacgccggaa tacgcggaag ccattgacac tttcaacgcc gccaacggtt accagctgga
     1681 gcccaaagcc aagaaaattc tcaaagggct ggcctttcgg gaaagcgact tccatcgccc
     1741 cgcccgggaa atgtccggcg gctggatcat gcgcgcgtac ctggccaagc tccttgtcct
     1801 ggagccggac ctcctgatgc tggacgaacc taccaaccac ctggacctcc tgtccctgct
     1861 gtggctccag cgatacctga aaaactaccc cggagccatc ctgatgattt cccacgaccg
     1921 ggatttcatg gatgagctgg tggaaagcgt gtacgacatc gacaacgaag aactggtgga
     1981 ataccgcggc aattactcgg acttcctcca acaaaaggac gtgcgcttcg agcagcttca
     2041 ggcggcctac cgcaaccagc agaaggaaat agcgcacatt caggaattta ttgaccgttt
     2101 ccgctccatc aattccaaag ccgggcaagt ccagagccgc atcaagcagc tggaaaagat
     2161 gaaaatcatt caaaaaccgg tagcccgcag gaaagtattt aaattcaact tcccccagcc
     2221 tccgcgcagc acccagaaag tcattgagct ggaaaaagtc tgccaatcct atggcgaccg
     2281 cagggtttat gaaaacctgg acctgctggt ggaacgcggg gagcgcactg ttcttgtagg
     2341 cccgaacggc gcgggcaaat ccactcttct caaaatcctg gcgggcatca tccccattga
     2401 ctccggacaa cgcactcccg gtaccacgac gcgcatcggc tacttctccc aggcgcgaac
     2461 ggaaaacctg aatccggaaa ataccgtgct ggaggaaatc atgaaatgca gcgctgaaat
     2521 ccgggaggaa gaagcgcgtt ccatcctggg ttccttcctg ttccggaggc tggatgtgga
     2581 aaaacgcgtc agcgttcttt ccggcgggga aaaatcgcgg ctcagcctgg tcaaattcct
     2641 ggtggatccg cccaacctcc tgctgatgga cgagccgacc acccacctgg accttttgtc
     2701 cgtagaagcc ctggtgcagg ctctgaagca ttatgaagga acactggtct tcatctccca
     2761 cgatgtgcac ttcatccgtt ccctggcaca aaaaaccctg catgtgaacc gggggaccat
     2821 caccgcctac gcaggtggat atgactacta tctggaaaag tcaggcattc tggacgatga
     2881 aaaaggcggc atcacggcgg aataaggctc ttttttcagt ttcccctttt tccttgccgt
     2941 ggatttcatc ctgccttaaa agaacaggat gaaggctttt cttgttcctc tcttatattc
     3001 tgcgcttctg tccggagcct ctcttgcatt tggtgaaacg gccgccggaa cggcttcccc
     3061 cgcagcagcg gctccggcgg aaaaaattcc ttccgcggaa tccctgatca accaggcctt
     3121 ttcctttgcc atcaatatcc agcagacgtt ggcaggcgtt caggacaagg aaagcgcgga
     3181 caacgccgtc aaaacgctgc aggacattca gaaggacatc cggcatttcc tccagcttca
     3241 ggataaattg aacgatgcgg aaaaggagaa agaagacgcc ttgatagaaa aaatggaaaa
     3301 acgaatggaa atgctggaca accgctgcag gcaggaaggc aaacgcctgt ttgaggcccg
     3361 ctattacggt tccgccgcct taaaggacat tttggaaaat tcggatgaat tcagcgacct
     3421 ggtagaaccg gatgaagacg ggacgccccc cggtgcactc cgggaaaatg aagaggccgg
     3481 acagtagccc cccgccccgt ttctcccccc ctcttttttc attcccggca cgccccttcc
     3541 ccgtatgggt tcctgcgcgg ccaagtccat ttcaagcttg ccggaaccgt gaaaaacggg
     3601 tttactgtgg gcagcatgca aaagttagca ggtaaaacag ccatcgttac cggcgcgggc
     3661 cgcggaatcg gcaatgccgt cgcgcgccgc ttcgcttcgg aaggagccag ggtcatcctg
     3721 atcagccgca gtccatccag ctgcgggggg gccgcagaag aaatcaacaa ggaatttccg
     3781 gattcctgca aggcctaccc ctgcgacgta gcggattacg cggccgttca ggaaaccatg
     3841 gccgccattt tgaaagactt cccgcagatt gacatcctgg tgaacaacgc cggcatcacg
     3901 cgggactccc tgatgctccg catgaaagag gaagactggg atgctgttct ggacaccaac
     3961 ctgaaaagcg cgttcaatac ggtcaaggcc ctccagcgcg ttctcatgaa atccccggcc
     4021 gggcgcatca tcaacatgag ctccgtcatc ggtctcgtcg gcaacatcgg ccaggccaat
     4081 tacgccgctt ccaaggcggg tctcatcggt ttcaccaaat cactggctca ggaattcgct
     4141 ccgcgcaaag tcacgtgcaa cgccattgct cccggcttca tctccacgga aatgtccaat
     4201 tccattcccg acaatctcaa ggaagaaatc gttaagaaaa tacctttgaa agaacaaggt
     4261 tccgtggaag atatcgccgc cctgacggcc ttccttgcct ctgacgatgc ccgttacatc
     4321 accgggcagg tcattgcctg cgacggaggc atgacgatgt agggcattcc ggttttctcc
     4381 attccatgcg cggcattttc cttgtttcct gctttctggg aggaagcgcc ctgctggccg
     4441 ggtgccggga agaaaataat tccccccgcc cggccacgga agatgccgcg cgcattacca
     4501 gcgcacgcca gtggggagaa agccgatccg cgctgcaaaa acgggaactg gaccgcgctg
     4561 ccggtcctgc ccttcccatt ccggatgacc tgccgtcccg ggagctggtc ggcacaacgc
     4621 gccaaatcca tcagctcatt gaagcttccg gaaatccggc acgttttgaa tcctacacgg
     4681 aaacggttcc cgtggcggga gcttccctgc gcatggtcgc cataccggga ggaacgttcc
     4741 tcatggggag tcccgcggaa gagccgcacc ggaaaccgga cgaaggtccg cagcataaag
     4801 tgagcatctc ccccttctgg atctcggaaa cggaaatccc ctgggaactt tatacggcct
     4861 tcatggaaaa cgggcgtccg cgcgccaagg acggccagct tctggaggaa cagccggatg
     4921 acgaactgtg ggactccgtt acgcagccta ccgcccccta caccgccatg aacctgggca
     4981 tgggccacgg ctatgaacac ggtctgcccg ccatctccat gtcccaccac gccgccagca
     5041 aattctgcga atggctgagc gcccagaccg ggcattacta ccgcctgccc acggaggcgg
     5101 aatgggaata cgcctgccgg gccggctccc ccggcgccta ttcttacgga aacggggaag
     5161 cctctctgga ccagtacgcc tggtactgga acaactccaa tgaccgctac cagaaaacag
     5221 gctctaaaaa accaaataag tggggactcc gggacatgca cggaaatgtg gcggaatggg
     5281 ttttggactc ttacgttccg gatgcctacg gcaaacggag cggcttgccc gcgaaagacc
     5341 ccttggtcat catccccggc gcccctcaca tcgttcgcgg cggttcgtgg gaagacgacc
     5401 cggacagcct gagaagcgct gcgcgccgcg ccagcacccc cgcctggagc cgtcaggatc
     5461 ctcaaaaccc taaaagcatc tggtacctga cggacggagg catgatcggg ttccgcgtgg
     5521 tgcgccccat gaacattccg gacattatga cgatgcaccg cctctggaat ttctccaagg
     5581 gggagccgta aagaacaacc tttcatgacc attgcattaa gaacggaaca atcctcagac
     5641 catgccgaaa cggaacatgt cacgagagaa gcgttctgga actatttcgt ccccggctgc
     5701 catgaacatt acctgctcca tatcatgcgc gtcagtccgt ccttcatccc ggagctggat
     5761 gcagtcgccg tccacggcag ccgcatcgtc gggaaacatc gttgatgcaa cgtccgtcat
     5821 cagggcagac gatggaaaag aatatgaagt gctgggcatg gggcccattg ccgttcttcc
     5881 gaaataccag cgccggggaa taggacggcg aataatatgt atgcggcggc cctccaggtc
     5941 tgtgagctgc aaaggggttc cctatccggc ctgaaaggcc actatgtgaa agctgccgtg
     6001 taccatatgg acgaaaagcg cgctgccgaa tttgacggca ttttccggta aagaaaaagc
     6061 tttccggtac tgcgtctcaa aaacgtttcc agcaaattgc cgccatgccg aaaaaaccgg
     6121 atacggcccc ctgcccccgg aaattccgta ccttccggag ggcatgaatc ccgcatacgg
     6181 ataagcaatt cttcctctct ggatataaaa aacaagagct gttccgcaag aacagctctc
     6241 atccgccgat ttttcgccat caggaagctc aagccctgcg tcggcgcatc atcagcgcgg
     6301 ccagtcccag caggcccagg gaaaccgtgg ctggttccgg caccatttcc cctcggattt
     6361 ccgtgaaaat cggggataat aagctgaaag tattggttcc gttggctccc gtaataacga
     6421 cagaatcacc aggcgctccc tcggcgtcat aatggccgcg gatgccggga gcagtcaatc
     6481 cgccgctgat cgttacggta tctccttccg tgttagcagt aggggcggct gttccccccg
     6541 cagcatataa atacgtttta gacgtatcct gcatcaagtc catcacggac tggctcacgg
     6601 ccaggaaacg gtatgtcaat gccgcgtcaa gaagcagggg agaaccatcc agggaagaaa
     6661 aactgaacgt cagattaatc cctgctgcag tagttcccgt attggtgctc cagccgatga
     6721 ccgaattgtc ggagccattc agcaccagga agccgtaagt gacattagcg cccaaattgt
     6781 tggcggctcc gcgcagcgta aaactgtcca gtctgatctc tccggacagg gaggagggag
     6841 aagaggaatc ggaaggagcc agggaagaag accccaggcc aagataaaac ccatggatgg
     6901 tactattgta attatccgta ccgggagtgt aataattaaa aacggtcgct gcctccgagg
     6961 aaacagcaaa gcttcccatc gcgattaaaa atgtcagtgt tttcttcata tttattattc
     7021 cttttggatg gcaacttgta gcgaatttgg aattccccaa tcgaatttgg aatccgtcaa
     7081 gtaatgaaaa agaggccaaa tcaatcatga aaccaatgaa taacaaagac tgacccgtca
     7141 tcttagcaaa aggaccagag atattaaaaa atcattattt tcaatgaatt ataaatacaa
     7201 tatactaact cttaatattt ttaattgctt gcggattcca aattcgttat tcaagcacaa
     7261 gtacatacat tgaaccttga atcattttat taagatactg accatgaata aattattatc
     7321 caccctgatt ctttcggccg gcatgagcct aagcgctacc gcggctaccg ctctgttgga
     7381 tagctccatc gtgggatatt cggactttgc ctcccaaacg gcggatttcg gcacccggaa
     7441 agattccgtt tccatcacgt ctgacgacag caatctgacg ttgtccggga taaccttcaa
     7501 cggatacggt gccaacaacc gcgacgttat gtctgtgacg atggttcttg acctgtccaa
     7561 aatcaacact ccggagacct ataccgctct gtttaacgcc aaaaacagca gtgtaagctg
     7621 gggcgtgggc ctgaacacgg accggaaact ccagggatta tggaacaaca cctcatacaa
     7681 cgggcccgtc gttgacaccc cgctgggcac ggaaggttcc ctgaccattt ccgtagtcac
     7741 cggagatctt ggcacccgca tctattttgg agacagcgct acgtactatt ccaacagcgg
     7801 cctgaaattc ggcaaccagc aaattgatca gattctcatg gacgcaggac tggctgaatc
     7861 catcgaacag ctctacattc acgactccct cctttcccag gaacaagttg gtcaactgat
     7921 gagtgaaatc gccagcatcc cggaacccgc cacggcttcc ctgggcctgc tgggactggc
     7981 cgcgctgatg atgcgccgcc gcagggcata agcctgtacc gtccgcctcc ctatattcaa
     8041 aggccggctc acaaaatcgt gagccggcct tttccttatc cgttcaaaca tctgccggaa
     8101 aaaacagggg ggaagaagct tccatttgct gcggtaccct cacggccagc acttgacggg
     8161 gaaatggcat tcaggctccc ccgggagggt catttcaaga gcttccggcc ccgccccact
     8221 tccgtacacg cccctttttc ccatgccggg acagccggaa ccggagcatg caaagcccgg
     8281 cttccctcag catccggaac agcccatcct ttcagcaatc catttccccg cacggtccgg
     8341 atcgctgcgg tttccgtccg tcggcaacag actccttccc cgaaacaggg aaaaggagtg
     8401 ggaaaatggc tgagcttgaa cctttatccc ccgttcccgt ccatgaacct tcaaaaacag
     8461 cagctgctac tgcgcctgtt ccggtatttc aaaagcagaa aaggagaacc gcgttttttc
     8521 aacaaacgga atatatgcct tctggccgcc gccggcgcct acatcctgac tcccgacgaa
     8581 ttcctgtttg acggaatcgg caggctgggc cttctggatg acgcggcggt catcctgggc
     8641 gccgtcctca ccgtcttttt cccggacggg gactagaggg ccgtaccctc cgccgcgccg
     8701 cgggcggaat tagcgggatg acactttccg gaacttcggg gactgtccca tgaatgtctc
     8761 cggattttcc aggagaagac gttccgtttc ctgccgggaa aaaccgcgcc tgcgcagctc
     8821 gcaggccaag gccgtcagcg ccaggggatc ggaatccccc cagtccgccg cggaattggc
     8881 ccagacacgg tccattccgt acaattccag aatatccgcc gcccgcttgg gattcagctt
     8941 gctggtggga taaagggtca gcccggccca gtagccggcc tccttcacca gcgggaaggt
     9001 atgttcctca cagtgatcca ccagcacgcg gcaagggtcc agatccggac ggtttttcag
     9061 ggcggaaaga atcattacgg tccccttaag cttgtcttcc agatggggag tgtgaatcag
     9121 cacaagctgg ttgaggcgca ccgccagatc cagatgctcc tcaaaaatag tcatttcatg
     9181 ggaagtattc cggttcagtc ctatttcccc aatgccgagg acattgggcc ggtcgatgaa
     9241 ctccggaatc agtttcatta catcccgcgc gaaagccacg tcctgcgcct ccttgggatt
     9301 gatgcacagc catgtgtaat ggtccatgcc gaacttggcc gccctggcgg gttcgcattc
     9361 cgtaagctgt acgaaataat cccggaaacc gtccgcggac gaacggtcgt aaccggccca
     9421 gaacgccggt tcccctaccg ccaggcagcc ggcctgcgcc atggcccggt attcgtccgt
     9481 ggtgcggcac accatatgta tatgaggttc tatgaaagcc atcattctta tttgctgagg
     9541 ttcggggctc cgcaggccgc tttggctgcg gcggtttccg gcacggtgtc atccctgtag
     9601 gaaagggctt ccagaatggc ccggacgcgt ccggggccgg atgcggataa gaggggaaga
     9661 acatccatca gggcatggta acggaaatcc gcctcccctt ccccgcggtc cacccggtcc
     9721 agaaatgcgg ccacatccag aacgccggcg cgcgccgctg cgaaatccgc gtccagcact
     9781 tcctttttac ttcttttcat gcacagacga tacgcctatg cggaaagcct cgtcaagccg
     9841 gaacaggcaa caaaatgata accattccaa actgataaac agcaatctct ttccccggct
     9901 tttcaaaaat ccgaaaagcg ccggaaattc aagaagaggc ttgccatccg ggcttgaacc
     9961 gggcatcctg tgaagacgca tttatttcat tagagcgcct atgaatgcac tagtaaaaac
    10021 catatgtaca ttcgtgacat cctccatcgg ccgcaaaatc attgtggctc tgacggggtt
    10081 atgtttggtc ttgttccttg cgggacacct ggcaggcaac cttctcatct tcggaggccc
    10141 tgaatggatc aacacctacg cccacggcct gcactccatg ccggaagcag ccctctgggg
    10201 aatccgcgcg gggcttgcgg tgatcttcat catccacgtc tggctgacca tccagctgaa
    10261 gctggaaaac catgcggccc gcgaacccta cgtgttcaag aacaccatca aggcaacgct
    10321 ctcctcccgc tacatgatct ataccggtct gaccgtcctg gtgttcctga tctaccacct
    10381 gtaccagtac accctgcgcg taggatacga ccccgcccag ttcaccacct tcatttccga
    10441 cggtacggtg gaaacctttg acgtgtacaa gatgatcgtg accggatttt ccaacgtatg
    10501 gtgctccgcc ttctacatcc tggccgttct gatgctgttc agccatctgc gccacggggt
    10561 acagtccatc ttccagactg tgggcgtcga ttcccgcaaa atccggccct tctacaactt
    10621 tatcgccatc gcctacggcg cgattatctg cctgggcttc atctccgtgc cggtctcggt
    10681 tcttctgggt atcatcaaat aaccatcaac tcctctcaaa gtcatgatta attttcccgt
    10741 aagcgactgg atgccggatg ccaaaattcc ctccggccct attcaggaca aatggtccaa
    10801 gtacaagctt gagtccaaac tgatcaatcc gaacaacaag cgcaagtaca cggtgcttgt
    10861 ggtaggttcc ggcctggctg gcgcctccgc tgctgccacg cttgccgaac ttggctacaa
    10921 cgtcaaatgc ttctgctacc aggacagccc ccgccgcgcc cactccattg cggcccaggg
    10981 cggcattaac gcagccaaga actaccagaa cgacggcgac tccgtttacc gcctgtttta
    11041 cgacaccgtt aaaggcggcg acttccgcgc ccgtgaagcc aatgtctacc gtctggcgga
    11101 agtctcctcc aacatcattg accagtgtgt ggcccagggc gttcccttcg gccgtgaata
    11161 cggcggcctg ctggacaacc gctccttcgg tggcgcccag ctcaagcgaa ccttctacgc
    11221 acgcggacag acgggccagc agctcctgct gggtgcctac caggccctgg aaaaggaagt
    11281 ggccaaggga cacattgaaa tgttctcgcg ccatgaaatg atggatctgg tgctggtgga
    11341 cggcgaagcc aagggcatcg tcacccgcaa tctggttacc ggcgaaatca aatcctacgc
    11401 aggggatacc gtcctgctct gcacgggcgg ctacggcaac gtgttcttcc tgtccaccaa
    11461 cgcgatgggc tgcaacgtca ctgccgccta caaggcctac aagcgcggtg ccttcttcgc
    11521 caacccctgc ttcacgcaaa tccaccccac ctgcattccg gtcaagggcg actaccagtc
    11581 caaactgacg ctgatgtcgg aatccctccg caacagcggc cgcatctggg tgcccaagtc
    11641 ccgtgaaacc gcagaaaaaa tccgtaaaaa ggaaatcaag ccttccgatg ttcccgaaga
    11701 agaacgggac tactacctgg aacgcaagta tccctccttc ggcaacctgg ccccgcgcga
    11761 catttcctcc cgcgccgcca aggaagcctg cgacgacggc cgcggcgtgg ccatcaccgg
    11821 caagggcgtc ttcctggatt ttgcggatga aatcaagcgc atgggtcgcg aatggattga
    11881 cggccaatac ggcaatctgt ttgacatgta cgaagaaatc acggacgacg acccccatga
    11941 aacgcccatg atgatctacc ccgcctccca ctacaccatg ggcggcctgt gggtggacta
    12001 caacctcatg tccaatgtga aggggctgca cgtcctcggt gaagccaact tctccgacca
    12061 cggcgccaac cgcctgggag cctccgccct gatgcagggc ctgtctgacg gctacttcgt
    12121 cattcccgcc acgctgcccg cttacctgac gaccaccaaa cccggcgccg tcaccaccgc
    12181 cgccccggaa ttcaaggctg cggaagacga agtgaaggaa cgcatcaaca agctcctgaa
    12241 tgtgaagggc accaagacgg tggactcctt ccaccgggaa ctgggcctca ttatgtggga
    12301 agactgcggc atggcccgca cggaagaaag cctgacccac gccattgaac gcattcccca
    12361 gctccgcaag gaattctggg aaaacgtgcg cgtaaccggc acggcggacg gcatcaacgc
    12421 ggaactggaa aaagcctgcc gcgtggccga cttcctggaa ttcgcccagc tgctctgcta
    12481 tgacgccctg aaccgccagg aatcctgcgg cgcccacttc cgcgtggaat accagctgcc
    12541 ggacggcgaa gctaagcgca acgacgatga atacgcctat gtagccgcct gggaatacac
    12601 tggcgtggac agcctgcctg ttctccacaa ggaaccgctg accttcgaga acgtgcacct
    12661 tgccatccgc agctacaagt aaagatagcc aatacattaa cactcaaaag aaagattata
    12721 acatggctaa aacactcaat ctcactctca aggtctggcg ccaggaaaac cgggaagcca
    12781 agggccgcat tgagacctat gccgccaagg acattccggt ggacgcctcc ttcctggaaa
    12841 tgctggacat cgtcaatgaa ggcctggtca aggaaggcaa ggaacccatc cattttgacc
    12901 acgactgccg ggaaggcatc tgtggcatgt gctccctgac catcaacggc attccccacg
    12961 ggccggaacg ccaggtgacc acttgccagc ttcacatgcg caagttcaag gacggcgata
    13021 ccgtctggat tgaacccttc cgcgcgaagg ctttcccaat cctgcgggac ctgatggtgg
    13081 accgctccgc cctggaccgc atcatcgccg ctggaggcta tattgacgtg cgtaccggtt
    13141 ccgcgccgaa cgccaacaac atcgccgtgg aaaaagtgaa ggcggacgcc gcctttgacg
    13201 cggccgcctg catcggctgc ggcgcctgcg tggcctcctg taaaaacgcc tccgccatgc
    13261 tgttcacctc cgccaagatc gcccatctca atctgctgcc gcagggccag ccggaacgtt
    13321 ccaagcgcgt cctggccatg atgaagcaga tggaagcgga aggctttggc aactgcacga
    13381 accagtatga atgtgaagcc gcctgcccga aaggcatcag cgtggacaac atcgcccgcc
    13441 tcaaccgcga cttcatgcgg gccaacgcca aggaaggcct ctgtttctaa agaagattcc
    13501 ttcttaagac gctctgtaaa aactcccggc ggcatcggct gtcgggagtt ttttcattac
    13561 caggtttcct tgaaccagga ataaaatacc agacagttgc ttcctcatcg tcgcgcagcg
    13621 taaaaaattg ttacaccgga aggcacccag taatccagga aaccgtactt ggaaatgccg
    13681 gacgaaacct aagcaggccc cgtccgacag cgacggcccc atctttcttc gagagagaga
    13741 aacattgatt acaggaatta gactgatgcc cggaagggat ggcatcctgt caag
//
