LOCUS       c00043_gnlPro..        10510 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HIFOIJLJ_43.
ACCESSION   c00043_gnlPro..
VERSION     c00043_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 07:17:53
            Original ID  :: gnl|Prokka|HIFOIJLJ_43
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 10510
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..10510
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[7249:10508]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      7250..10508
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..10510
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..10510
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             2..487
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg43_1"
                     /sec_met_domain="Aminotran_5 (E-value: 5e-15, bitscore:
                     44.9, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="AGVTLAIVRVDALGHVDRPIPTMLNYATHIKKDSMFNTPPVLPIY
                     AALQTLKWYKEQGGIAAMEKKDLENAAILYDEIDRNKLFRGTVAEEDRSIMNVCFVMND
                     EYKELEDEFSKYATAAGMVGIKGHRSVGGFRASLYNAMPKSSVEALVACMKEFEKQH"
     CDS             505..1428
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Hacid_dh_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg43_2"
                     /sec_met_domain="Hacid_dh_C (E-value: 2.3e-36, bitscore:
                     114.5, seeds: 144, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKILVATEKPFAAVAVKGIREVVEGAGMELALLEKYTEKAQLLD
                     AVKDADAVIIRSDKVDAEVLDAAKNLKIVVRAGAGYDNVDLDAATAHKVCVMNTPGQNS
                     NAVAELVFGMLVYGVRNFYNGTSGTELKGKKLGILAYGNVGRNVARIAKGFGMEVYAYD
                     AFCPASVIEADGVKAVASTADLFKACQIVSLHIPATAETKGSINFELMNSMPKGAIVVN
                     TARKEVMDEAGLAKMLEERPDFKYLTDIMPAIHAELAEKYAGRYFSTPKKMGAQTAEAN
                     INAGIAAAKQIVDFLVNGNEKYRVNK"
     CDS             1501..2748
                     /locus_tag="ctg43_3"
                     /transl_table=11
                     /translation="MAKIKPFKGVRPPKEFIEEVASRPYDVLNSQEARVEAEGNEKSLY
                     HIIKPEIDFPEGTDEHDPAVYLKAAANFNNFQEKGWLVQDQKECYYVYAQTMNGKTQYG
                     LVVGAYVPDYMNGTIKKHELTRRDKEEDRMKHVRVNNANIEPVFFAYPDNSELDAIVMK
                     YTAREPEYNFVAKLDGFGHTFWIIDEDKDIARITELFGEMPALYIADGHHRSAAAALVG
                     AEKAKQNPGHKGDEEYNYFMAVCFPANQLTIIDYNRVVKDLNGLTEEQFVERLTKNFVV
                     EEKGSAIYKPGALHNFSLYLGGKWYSLTAKPGTYDDNDPIGVLDVTISSNLILDEILGI
                     KDLRSDKRIDFVGGIRGLGELKRRVDSGEMKVALALYPVTMKQLMDIADTGNIMPPKTT
                     WFEPKLRSGLVIHKLD"
     CDS             2871..3503
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg43_4"
                     /sec_met_domain="HAD_2 (E-value: 1.4e-09, bitscore: 27.9,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGKIKNIVFDLGGVIIDLDRDEPVRRLIEIGVKDADGLIDPYEQK
                     GVFQDLETGKIGVEEFCRYLRKYTGKDLSYEDICWAWFGFIGGVPQYKLDYILKLREKY
                     QVYLLSNTNPIIQLEWAQTKEFTPAGRPLNDYFDKLYLSYEIGVTKPDREIFDRMVLDS
                     GIRPEETLFVDDGKNNIVVGQELGFHTYQPLNGEDWRGRLDEILSKS"
     CDS             3542..4078
                     /locus_tag="ctg43_5"
                     /transl_table=11
                     /translation="MTNTTLNLEELLCGVNELVDTLWIVTLGNEKVEIIKDSMTPEREG
                     ECLDYTELCQTYIQEYVYPADLGKWEEILSLNSLRQMAASGVANKKFDMRFCNDLFGFE
                     WHEAFIRILKDKSGIPDRVILFSRYVNHCRKAQIVEAAVQTEYDYVVYIEANTNSYVMY
                     TSNRESGTPVPPDSE"
     CDS             4250..5923
                     /locus_tag="ctg43_6"
                     /transl_table=11
                     /translation="MRFSFFDKERNILLLTRTDIMEVREEERQRQLLQDALQVAKSANQ
                     AKSDFLSRMSHDIRTPMNAIIGMTTIASMHIDDRERIVDCLKKIMVSSKLLLNLINEVL
                     DMSKVESGHILLTDEEFDMGELLQSVITMVQTSVSQKFQDFRVHLFQVKHEKLIGDVQR
                     IQQVLLNLLSNAIKYTPDYGKITLEIREKPIKNGNYGLFEVTVIDNGIGIKPDFLHKVF
                     EPFERAEDATLRNIQGTGLGMAISRNIAHMMNGEIQVESEYGKGSVFTFTMQLKLQDQG
                     CFEDDHLRDLPVLVVDDDIVCCENACMRINEIGMKGEYAISGEEAIGKVERAHHLNDDY
                     FAVILDLKMPGMDGIETATRIRKVVGRDIPIIILSAYDCPHFEEIAQRAGVDGFISKPL
                     MKSKLFYLMKSFAIKQEKKEEETEKPQYPFGNFEGKRILLVEDNSLNREIATVLLEETG
                     AVVEEAENGLVAVNMVKNSSPGYYDLVFMDIQMPVMNGYDSTRHIRALERPDIKSMPIV
                     AMSANAFAEDIKLCKESGMNEHIAKPIDFGKVLEILEKYL"
     CDS             complement(5994..7034)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg43_7"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 7.9e-50, bitscore:
                     159.7, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKKILVAGGTGYIGSHTTVELQNAGYEVVIIDDLSNSNIEVLDG
                     IEKITGIRPEFIQLDLKDKEGTRKALEAHPGIKGIILFAASKAVGESVQQPLKYYRNNI
                     VTLVNLLEMMPEFNIEGIVFSSSCTVYGQPDPENLPVTENAPIKPAMSPYGNTKQINEE
                     IIRDTIHAGAPFKSIILRYFNPIGAHPSAEIGELPNGVPQNLIPYLTQTAMGIRKELSV
                     FGDDYDTADGSCIRDYINVVDLAKAHVIAMDRMLENKSDEHIEIFNLGTGNGVSVLELI
                     NTFEQTTGVKVPHKIVGRREGDIEKVWANPEHANKVLGWTAKETLADTLQSAWNWQKRL
                     RERGIQ"
     CDS             complement(7250..7642)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_8"
                     /sec_met_domain="Rnf-Nqr (E-value: 2.2e-26, bitscore: 82.6,
                     seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFIAAVFVNNVVLAQFLGICPFLGVSKKVETAAGMGAAVT
                     FVLTIATIVTFLVQKYILDAFGLGFMQTISFILIIXXXXRLGSDGGNHIEEGLSRPLSS
                     VGCIPSVDHHELLYLGCGYPCNPKRV"
     CDS             complement(7655..8239)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_9"
                     /sec_met_domain="Rnf-Nqr (E-value: 5.5e-69, bitscore:
                     221.3, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNLKILMNGIITENPTFVLLLGMCPTLGTTSSAINGMSMGLATM
                     FVLICSNIVISALKNVIPDLVRIPGYIVVIATFVTVVQMCMEAFVPALYASLGLFIPLI
                     VVNCIVLGRAEAFAAKNGVIPSAFDGIGIGLGFTMALTLLGACREFLGTGKLFNVTLMP
                     EEYGSLIFVLAPGAFIALGYLVAIVNKLRKA"
     CDS             complement(8257..8841)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_10"
                     /sec_met_domain="FMN_bind (E-value: 4.3e-26, bitscore:
                     81.1, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLSLTGICLVAGAILAGVNQFTAGPIAVAKATALEEAIKAVAPE
                     FDNKPTEDVYMAVSSDGDSLKIYPAKKGGQVVGGAVESNTKKGFSGEIRVIVGFDMDGK
                     ILNYSVLQHAETPGLGAKMQEWFRADKNKQSVLGRTIPDGGLKVTKDGGDVDAITAATI
                     SSRAFLDAVNRAYSAFAGVDGLTGATSTDNK"
     CDS             complement(8874..9842)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_11"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 5.8e-117,
                     bitscore: 379.8, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENNLYVSPSPHIHGGDSISKNMYGVLIALIPAFLVSLYFFGLGA
                     LIVTVVSVLACMIFEYLIQRFLMKKEPTLCDGSAILTGVLLAFNLPSNLPVWIIIIGAL
                     AAIGIGKMSFGGLGNNIFNPALVGRVFLLISFPAQMTTWPVVDALNVFPMTYTDAQTGA
                     TVLSLMNEGVTELPSYGNMLVGAMGGSLGEVSAVALILGLLFMLWKKIITWQIPVSILA
                     TVFVFTGIMHLVNPVQYASPFVHLLSGGLLLGSIFMATDYVTSPMSKNGMLVYGVGIGI
                     LTTVIRLFGSYPEGMSFAILIMNAFTPLINSYIKPKHFGGK"
     CDS             complement(9855..10508)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_12"
                     /sec_met_domain="Fer4_10 (E-value: 6.6e-10, bitscore: 28.8,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 9.4e-18, bitscore: 53.7,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 3.7e-14, bitscore:
                     42.6, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6.1e-06, bitscore: 16.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="EIMPLKVQYPQGGEKQLIDAVIRRQVKSGALPISAGAVVQNVGTA
                     YAVYEAVQKNKPLFERVVTITGKAVANPSNFLVRMGTPISCLIEAAGGLPENTGKIIGG
                     GPMMGKALISAEVPVCKGSSGVLLLTTEESVRKPIRDCIRCAKCVGVCPMGLNPTLLMN
                     ATEFQNWELAEKNYITDCIECGSCSYTCPANRPLLDQIRLGKGKVMGIIRSRKS"
ORIGIN
        1 tgccggcgtg actttggcta tcgttcgtgt ggacgcttta ggacatgtag accgtccgat
       61 cccgaccatg ttgaactacg ctacccatat taaaaaggat tccatgttca atacacctcc
      121 tgtattgcct atttacgcgg ctttacagac cttgaaatgg tataaggaac aaggtggtat
      181 cgccgctatg gagaagaagg atcttgagaa cgcggcgatc ttatacgatg agatcgatcg
      241 caataagttg ttccgtggta cggtagcgga ggaagatcgt tcgatcatga atgtttgttt
      301 cgtgatgaat gatgagtata aggagttgga ggacgagttc agtaaatatg ctactgccgc
      361 tggtatggta ggtatcaagg gacaccgttc tgtaggtggt ttccgtgcct ctctttataa
      421 tgcgatgccg aagagcagcg tggaggcttt ggtagcttgc atgaaagagt tcgagaaaca
      481 acattaatta aggaggattc agacatggca aagatattag ttgctacaga gaaacctttc
      541 gccgctgtcg ctgtgaaagg catccgggag gtagtggaag gcgctggcat ggaactggct
      601 cttttggaga aatatacaga gaaggcgcaa ttgctggatg cggttaagga tgccgatgcc
      661 gtgattatcc gtagcgataa ggtggacgct gaggtattgg atgccgctaa gaacctgaag
      721 atcgtggttc gtgccggtgc ggggtatgat aacgtggact tggatgcggc tactgcccat
      781 aaggtatgcg tgatgaatac gccgggacaa aactctaacg ctgtcgccga attggtattc
      841 ggtatgttgg tgtacggggt tcgtaatttc tataacggta cttccggaac agagttgaaa
      901 ggaaagaaat tgggtatctt ggcttatgga aacgtgggcc gtaacgtggc tcgtatcgct
      961 aaaggcttcg gtatggaggt ttacgcttac gatgcgttct gtccggcttc cgtgattgag
     1021 gccgatggtg tgaaggctgt agcttctaca gccgatttgt ttaaggcttg ccaaatcgtc
     1081 tctttgcata ttccggctac ggccgagacg aagggttcta tcaatttcga gttgatgaat
     1141 tccatgccga agggagctat cgtagtgaat acggctcgta aggaggtgat ggatgaggct
     1201 ggactcgcta agatgttgga agagcgtccg gacttcaagt acttgacaga tattatgccc
     1261 gctatccatg cggaattggc cgagaaatat gccggtcgtt atttcagcac cccgaaaaag
     1321 atgggtgccc agaccgccga ggctaatatc aacgctggta tcgccgccgc caagcagatc
     1381 gttgatttct tggtgaatgg caatgaaaag tatcgggtta ataaataaga atatccggtt
     1441 gtagagacgg ggcacgcccc gtctctacat tgatacataa accaattaga tttaattacc
     1501 atggcaaaaa taaaaccttt caagggagtt cgtccgccaa aagaatttat agaggaggtg
     1561 gcttcccgtc cctatgacgt attgaactcg caagaagctc gtgtggaagc ggaaggaaac
     1621 gagaaatccc tttaccatat cattaaaccg gaaatcgatt tcccagaagg gacggatgag
     1681 catgatccgg ctgtttacct gaaggccgcc gccaatttca ataattttca ggaaaaaggt
     1741 tggttggttc aggatcagaa agaatgctat tatgtttatg cccaaaccat gaatggcaag
     1801 actcaatatg ggttggtagt cggggcttat gttcccgatt atatgaatgg cacgatcaag
     1861 aaacatgagc tgacccgccg tgacaaggag gaggatcgca tgaaacacgt acgtgtcaac
     1921 aacgctaata tcgagccggt attcttcgct tatcccgaca actcagagct agacgctatc
     1981 gttatgaaat atacggctcg tgagcccgaa tataatttcg tggcgaaatt agacggtttc
     2041 ggccatacgt tctggattat cgatgaggat aaggatatcg ctcgcatcac ggagttattc
     2101 ggggagatgc ctgcgttgta tattgccgac ggacatcatc gttccgccgc cgctgctttg
     2161 gtaggagcgg agaaggccaa gcaaaacccg ggtcataagg gagacgagga gtataactat
     2221 ttcatggctg tttgcttccc ggccaaccaa ttgaccatta tcgattacaa ccgtgtggta
     2281 aaagacttga acggcttgac cgaggaacaa ttcgttgaga gattaacgaa aaacttcgtg
     2341 gtagaggaga agggctctgc tatttacaaa ccgggtgcct tgcacaattt ctccctgtat
     2401 ttaggaggga aatggtattc tttgaccgct aagcccggta cgtacgatga taatgacccg
     2461 ataggcgtat tggatgtcac gatctcttcg aacttgattc tggatgagat tttaggcatt
     2521 aaggatttac gttcggacaa gcgaatcgat ttcgtgggag gtatccgtgg cctgggtgaa
     2581 ttgaaacgcc gtgtggatag cggtgagatg aaggttgcct tggctttgta tcccgttacg
     2641 atgaagcaat tgatggatat cgccgatacg ggtaatatca tgccgccgaa gacgacgtgg
     2701 ttcgaaccga agcttcgctc cggtttggtg atccataaat tggattaagt cttatataca
     2761 taaatatagc tttggattgg ggtataatcg ttgaagatta tacccttttt tatccttgta
     2821 acctagatat acggaataaa ttgtatcttt gggacttaaa tagtatcgca atgggtaaaa
     2881 taaaaaatat agtattcgat ctggggggcg ttatcataga tttggaccgg gatgaacctg
     2941 ttcgccgttt aatagagatt ggggtcaaag atgccgatgg attgatagat ccttacgaac
     3001 aaaaaggggt ttttcaagat ctggagaccg gaaagatcgg agtagaggag ttttgtcgct
     3061 atttacggaa gtatacgggt aaagaccttt cttatgagga tatttgttgg gcttggtttg
     3121 gcttcattgg cggcgttccc caatataaat tggactacat attaaaactc cgtgagaaat
     3181 atcaagtcta tttattgagc aatacaaatc cgatcataca gcttgaatgg gcacagacaa
     3241 aagagtttac gccggcgggc cgtccattaa atgattattt cgataaattg tatctctctt
     3301 atgagatcgg tgtcacgaag ccggatcgtg aaatttttga tcgcatggtc ttggattcag
     3361 gaatcagacc agaggaaaca ttatttgtag atgatggtaa gaataatatc gtagtggggc
     3421 aggaactagg gttccatacc tatcagcctt tgaatggaga ggattggaga gggaggctcg
     3481 atgaaatact ctcaaaatca taggatctct attcctctta attaaatcta tatcattgaa
     3541 aatgacaaat actactttaa atttggaaga actactctgt ggtgtaaacg agctagttga
     3601 tacgctttgg atcgtcacat taggtaatga aaaggttgag ataatcaaag attcgatgac
     3661 tcccgaaagg gaaggagaat gtttggatta tacagaactt tgccagactt acattcaaga
     3721 atatgtatat cctgcggatt tagggaaatg ggaggagatc ttatccttga attcattgcg
     3781 gcaaatggcg gctagcggcg tagcgaataa gaagttcgac atgcgtttct gtaatgattt
     3841 gtttggtttt gagtggcatg aggcttttat tcgtatcttg aaagataaga gtggaattcc
     3901 ggatcgtgtc attcttttca gccgctatgt gaatcattgt cgcaaggcac agatcgtaga
     3961 ggctgccgtt cagactgagt atgattatgt cgtttatata gaggcaaaca cgaatagcta
     4021 tgtcatgtat acttccaatc gtgaaagtgg gacgccggtc ccccccgata gcgagtaatg
     4081 actatgaaaa agaggtagcc gagttccacc acaaatatgt gccggaggat cagcgagatg
     4141 agttaacccg aaatctttcc ctagatcatg tcttatctgt cttacgaaat tcccgtgagt
     4201 atgtcttgtt ctgtcaggtg atggagaatg gcgttttagg gataagaaga tgcgttttag
     4261 ctttttcgat aaggagagga atatacttct tttgacccgg accgatatta tggaggttcg
     4321 tgaggaagag cggcaaaggc aattacttca agatgcccta caagtggcta aatcggcaaa
     4381 tcaggctaaa tcggatttct tatcccgtat gagccatgat atacgtactc cgatgaatgc
     4441 cattatcggt atgaccacta tcgccagtat gcatatcgac gatcgggagc gtatagtgga
     4501 ttgcttgaag aagattatgg tttcttccaa attgttattg aacttgatca atgaggtctt
     4561 ggatatgtct aaggtagaga gcggacatat tttgctgaca gacgaggagt tcgatatggg
     4621 cgagttattg caaagcgtaa ttactatggt tcagacttcg gtcagtcaga agtttcagga
     4681 tttccgggtt cacttgtttc aagtcaaaca tgaaaagctg attggcgatg tgcaacggat
     4741 tcagcaagta ttgttgaatt tgctgtcgaa cgccataaag tatacgccgg actatgggaa
     4801 aataacactt gagatacggg aaaagccaat taaaaatggt aattatggtt tatttgaggt
     4861 tacggttata gacaatggta tcgggataaa gccggatttc ttacacaagg ttttcgagcc
     4921 atttgaacgt gcggaagacg caaccctgcg gaatatacaa ggaaccggct taggcatggc
     4981 aataagccgt aatatcgctc atatgatgaa tggtgagatt caggtggaga gtgaatatgg
     5041 caaaggttcc gtttttacat ttacgatgca gttgaaattg caggatcaag ggtgttttga
     5101 ggatgatcat ttaagggatt taccggttct cgtggtagac gatgatatcg tgtgttgcga
     5161 gaacgcatgt atgaggatta acgagatcgg aatgaaaggc gagtatgcca tttctggtga
     5221 ggaggctatc gggaaagtag agagggcaca tcatcttaat gatgactatt ttgccgttat
     5281 ccttgatctg aaaatgccgg gaatggatgg gatcgagacc gctacccgta tccgaaaagt
     5341 cgttggccgg gatattccga tcattattct ttccgcttat gattgtccgc attttgagga
     5401 aatagcccaa cgagccggtg tcgatggatt cataagtaag ccgttgatga aatccaagtt
     5461 attttatttg atgaaaagtt tcgctatcaa gcaagagaaa aaagaggaag agacggagaa
     5521 gcctcaatat cctttcggta actttgaggg taagcggatc ttgctggtgg aagataatag
     5581 cttgaatagg gaaatagcga ctgtgttgct agaagagacc ggtgcggtgg tagaggaggc
     5641 ggaaaatggc cttgtcgcgg tgaatatggt aaaaaactct agtccgggat attatgactt
     5701 ggtatttatg gatatccaga tgccggtcat gaacgggtac gactctactc gccatattcg
     5761 ggcattagaa cgtccggata tcaagtccat gccgatagta gccatgtctg cgaacgcatt
     5821 tgcggaagac atcaagttgt gtaaagaatc cggaatgaat gagcatatcg ctaagccgat
     5881 cgatttcggg aaggttcttg agatcttaga gaagtacttg tagatataag gatataaaaa
     5941 aggccgtatc cttagctaag cgctatcaga tacggcctct ttttttgtgt tatttactgg
     6001 atgccacgtt ctctcaaacg tttctgccag ttccatgcgg attgcagggt gtcggctaaa
     6061 gtctccttgg cggtccagcc taatacctta ttcgcgtgct ccggattggc ccataccttc
     6121 tcgatatcac cttcacgacg gcccacgatc ttgtgcggaa ccttaacgcc tgttgtctgc
     6181 tcgaaggtat tgatcagttc aaggacagaa acaccattgc cggtacctag gttgaatatc
     6241 tcgatatgct catcagactt attctcaagc atacggtcca tagcgattac atgtgctttc
     6301 gccaagtcta cgacattgat atagtcacgg atgcaagaac cgtctgctgt atcataatca
     6361 tcgccgaata cgcttagttc cttgcggata cccatagccg tctgtgtcaa gtacgggatc
     6421 aagttctggg gaacaccatt cggcaactcg ccgatctctg cgcttgggtg tgcgcctatc
     6481 gggttgaagt agcgcaagat gatactcttg aaaggcgctc ctgcgtggat cgtatcccgg
     6541 ataatctcct cgttgatctg cttcgtgttt ccataaggag acatagcggg tttgatcggg
     6601 gcattctcgg ttaccggcaa gttctccggg tccggttgtc cgtataccgt acaagaggaa
     6661 gagaatacga taccttcgat attgaattca ggcatcatct ccaacaagtt caccaaagtg
     6721 acaatattat tgcgataata cttcaaaggc tgctgtacgg attctcctac cgccttgcta
     6781 gcggcgaaca agataatgcc tttgatgccc ggatgagctt ccaatgcctt gcgagtacct
     6841 tccttatcct ttagatccaa ttggataaac tccggacgga tgcccgtgat tttctcgata
     6901 ccatcgagca cctcgatatt cgagtttgac aaatcgtcga taatgactac ctcatatccg
     6961 gcgttctgca attctactgt ggtgtgtgag ccgatataac cggttccgcc cgctactaaa
     7021 atcttctttt tcattctagt gttcatttag ataagtttgt tatacgatac ccgagaatcc
     7081 cataaaagcc atagctagca aaccggccgt tatcaaggcg ataggagtgc ctttcatgcc
     7141 ttccggaaca tgcgtcatgg ctagttgctc ccgaataccc gcgaagataa tcaaagctag
     7201 cgcaaatcca atagcggtcg agatagcata taccacagat tctaataaat tatactcttt
     7261 ttggattaca aggatagcca cacccaagat acagcagttc gtggtgatca acggaaggaa
     7321 tacacccaac gcttgataaa gggcgggaga gaccttcttc aatatgattt ccaccatctg
     7381 aaccaaggcg gnnnnnnnnn ncgatgatca agatgaaact gatcgtctgc atgaacccta
     7441 atccgaaagc gtccaatatg tatttttgca cgaggaatgt aacaatcgtg gcgatcgtaa
     7501 gcacgaacgt aacggcggct cccatgcctg cggcagtctc cactttctta gataccccca
     7561 agaacggaca aattcccaag aactgtgcca gtacaacgtt attaacgaat acggcggcga
     7621 taaatatcaa tatatattcc atatgatccg tttattatgc tttacgtagt ttgtttacta
     7681 ttgctaccag ataacccaag gcgataaacg ctcccggagc caatacgaag atcagcgaac
     7741 catattcctc gggcatcaag gttacgttga ataacttacc ggttcccaag aactcacggc
     7801 aagcgcccag cagcgtaaga gccatcgtaa agcccagtcc gataccgatt ccgtcgaaag
     7861 cggatgggat tacgccgttc ttcgcagcga aagcctcggc acgtcctagt acgatacagt
     7921 ttaccacgat caacgggata aataatccca agctagcgta taaagccggg acgaacgctt
     7981 ccatgcacat ctgcactacg gtcacgaacg tcgcgatcac aacgatatat cccgggatac
     8041 gcaccaagtc ggggattacg tttttcaagg cggaaatcac gatattcgag caaatcaata
     8101 cgaacatcgt agccaatccc atactcatgc cgttgatggc cgaagaggtc gttcccaagg
     8161 taggacacat acctaacagt aatacaaatg tcgggttctc cgtgatgata ccattcatca
     8221 atatttttag attactcatt gctctgtcct ccctttttat ttgttatcag ttgaagtggc
     8281 acccgttaat ccgtctacgc ctgcgaatgc gctatacgca cggttcacgg catcgaggaa
     8341 cgcacggctg gagatggtcg ctgccgtgat agcgtccacg tcgccaccat cttttgttac
     8401 ttttaagcct ccgtccggaa tcgtacgtcc caagacactt tgcttgttct tgtccgcacg
     8461 gaaccattct tgcatcttgg ctcccaagcc cggagtctcg gcgtgttgca atacggaata
     8521 gttcaagatc ttgccatcca tatcgaaacc tacgataacc cgtatctcac cgctaaagcc
     8581 ttttttcgta ttactctcta cggctccgcc aacgacttgt ccgcctttct tggcaggata
     8641 aatcttgagg gaatcaccat cggaggagac ggccatatag acgtcctcag tcggtttgtt
     8701 gtcgaactcg ggagcaacgg ctttaatcgc ttcctccaag gcggtcgctt tagctaccgc
     8761 tatagggccg gcggtaaact ggttcactcc ggctaggatc gcccctgcta ccaagcaaat
     8821 gcctgttagt gaaaggagca tattgggtaa tgttgatttt aattttgcca tgcttacttt
     8881 cctccgaaat gtttaggttt gatatagctg ttgattagcg gagtaaatgc gttcatgatc
     8941 aggatagcga acgacatacc ttccgggtaa gacccgaaca aacggatcac cgtggtaagg
     9001 attccgattc ccacgccgta gacaagcatt ccgttcttgc tcatcggcga ggttacgtag
     9061 tcggtcgcca taaagatgga gcctaataac aaaccgccgg ataataagtg aacgaacggg
     9121 ctggcgtatt gtaccggatt caccaagtgc atgatgcccg tgaatacgaa tacggtagcc
     9181 aagatggata ccgggatctg ccaagtgatg atctttttcc atagcatgaa taaaagaccg
     9241 aggatcaagg ccacggcgct cacttcaccg agactacctc ccatagcccc tacaagcata
     9301 ttcccgtaag acggaagctc ggtcacgcct tcgttcatca acgacaatac cgttgcgccg
     9361 gtctgggcat ccgtataagt catcgggaaa acgttcaagg catctaccac cggccaagtc
     9421 gtcatctgtg ccgggaagga gatcaataag aatacacgtc cgactaacgc cggattgaaa
     9481 atattattac ctaatccacc gaaagacatc ttgccgatgc cgatcgccgc caacgctccg
     9541 atgataatga tccagaccgg aaggttggaa ggtaggttga aggccagcaa tacgcccgtc
     9601 aggatagcgg agccatcgca aagggtcggt tcctttttca tcaggaatcg ctggatcaaa
     9661 tactcgaata tcatacaggc cagaaccgat acgaccgtaa cgatcaacgc tcccagaccg
     9721 aagaaataaa gggataccaa gaaagccggg ataagggcaa tcagtacacc atacatattt
     9781 ttgcttatgc tgtcgcctcc atggatgtgg ggcgagggcg atacgtataa attattttcc
     9841 atgttgctct tgttttatga ctttctagac cggataatac ccataacttt tcctttaccc
     9901 aaccggatct gatccagcaa cggacggttg gccggacagg tataactaca cgacccgcac
     9961 tcgatacagt cggtgatata gttcttctcc gccaattccc aattctggaa ttccgtggcg
    10021 ttcatcaata gggtagggtt caatcccatc gggcagacac ctacgcattt ggcgcaacgg
    10081 atgcaatccc ggatcggctt gcggacagat tcctccgtcg tcagtaataa aacaccggag
    10141 cttcctttgc aaaccggcac ctcggcgctg atcaacgctt tacccatcat cggtccgcca
    10201 ccgataatct tacccgtatt ctcgggcagg ccacctgcgg cctcgatcaa gcaactgatc
    10261 ggggttccca tacgaaccaa gaaattggaa ggattagcta ccgccttacc cgtgatcgtc
    10321 accacacgct cgaacaacgg tttgttcttt tgtaccgcct cgtaaacggc ataagcagtt
    10381 cctacgttct gtaccacggc acccgccgag ataggaagcg caccactttt tacctgacgg
    10441 cgaataacgg cgtcgatcaa ttgtttctcg cctccttgcg gatattgtac cttaagcggc
    10501 atgatctcta
//
