LOCUS       c00092_gnlPro..        14849 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JADJOCNO_92.
ACCESSION   c00092_gnlPro..
VERSION     c00092_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 12:54:34
            Original ID  :: gnl|Prokka|JADJOCNO_92
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14849
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14849
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[707:4849]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      708..4849
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..14849
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14849
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(3..671)
                     /locus_tag="ctg92_1"
                     /transl_table=11
                     /translation="MEKNKVGEFHFVTESYLTDFRGRITIPMIGTYLLHAASCHAADRG
                     FGYNDMTERHTAWVLSRLAIEMTSYPAMSESVTLYTWVDEVGKLFTSRCFELVNGEGKT
                     FGFARSIWAAIDMETRRPTLLDVEGLSAYITDRPCPIEKPGKIAPVENNTSGEPYRVKY
                     SDLDVNGHLNSIKYMEHLLDLFDISLFREKEISRFEIAYQSEGKYGMELTLHNQEVSLD
                     K"
     CDS             complement(708..1274)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg92_2"
                     /sec_met_domain="ALS_ss_C (E-value: 1.5e-12, bitscore:
                     37.2, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKQLYTVIIFSENTVGLLNQITVIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDTIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEDLIRKYNARILEMNEDCVVLEKSGHYDETQALFKELSETIGVLQFIXXXXXXXXXA
                     ITKSKVERLSDMLSAMEKKLQEKHV"
     CDS             complement(1287..2987)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg92_3"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.7e-51, bitscore:
                     162.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRDQ
                     LKHILVRHEQGATHAAQGYARVSGKVGVTVVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRRPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGLVDYEYQKVDYVRSYQPEPDIREERIEAAASLINNAKKPFCLVGQGVILGG
                     AEEELKEFLLKNDIPAGSTVLGLSALPSDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVPVDVKVLGNAKHTIPMITALLEERK
                     RPEWNAEFEPDEKEEYNKVIEKELYPTEGQLKMGEVVRKVSEATDNDAILVTDVGQNQM
                     MGVRYFKYKQTRSVVTSGGLGTMGFGLPAAIGAKLGAPDRTVCFFTGDGGIQMTIQELG
                     TIMQENLNVKIIVLNNNFLGMVRQWQELFFNERYSNTIMKNPDFVAIAKAFGIASRAVD
                     KREDLDEAIAEMLNHDGAYMLVANVETCGMVYPMVPAGGSVTNMILGDK"
     CDS             complement(3014..4849)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg92_4"
                     /sec_met_domain="ILVD_EDD (E-value: 2.8e-218, bitscore:
                     715.1, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKNPLRSSYSTEGRRMAGARALWRANGMKEEQFGKPIIAIVNSF
                     TQFVPGHVHLHEIGQQVKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIAD
                     SVEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTIFVSGGPMEAGNLDGRALDLI
                     DAMIEAADDSISDEQVEKVERSACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTVVAT
                     HANRTRLFKKAAKMIVDNAFKYYRDGDDSVLPRSIATRQAFLNAMSLDIAMGGSTNTVL
                     HLLAVAHEAEVDFTMKDIDMLSRKTPVICKVAPSCSYHVEDVNRAGGIIGIMNELVKAG
                     LVDGSVKRADGLTLNEAIDQYCITSVNVTEEAINIYKSAPAHRFNLVLGSQESYYKELD
                     TDRATGCIRDVEHAYVKDGGLAVLYGNIAQDGCVVKTAGVDESIFRFAGPAKVFDSQDA
                     ACEGILKDQVVSGDVVVITYEGPKGGPGMQEMLYPTSYIKSKHLGKECALITDGRFSGG
                     TSGLSIGHISPEAAAGGAIGLVKDGDIIEINIPERTIHVKVTDEELAKRREAEEARGTK
                     AFTPPFRQRTVSKALKAYAKMVASADKGGVRIVED"
     CDS             complement(5167..6714)
                     /locus_tag="ctg92_5"
                     /transl_table=11
                     /translation="MAALYPIGIQNFEKIRKEGYLYVDKTALIYQMVKTGSYYFLSRPR
                     RFGKSLLVSTLEAYFQGKEELFEGLAMEKLEQDWLEYPILHLDLNAERYSEASSLDSIL
                     QRHLNLWEDTWGKDEREKTLSDRFIGVIRRAKARSGRRVVILVDEYDKPLLQAIGDELL
                     QDEYRSILKPFYGVLKTMDGDIRFALLTGVTKFGKVSVFSDLNNLMDISMDDRYVEICG
                     MTETEIHAYMEQGVLDLTRNLQMDYEEVCMELKRRYDGYHFTHRSQGMYNPFSLLNTFA
                     KSDFGDYWFETGTPSYLVELLKHTDYDLYNMAHTETNADVLNSIDAVSRNPIPVIYQSG
                     YLTIKSYNPRFKIYTLGFPNQEVEEGFLNYLLPYYTSVNVIDTSFQLFKFIKEIESGDV
                     DAFLSRLQSFFADTPYELIRNLEVHYQNVLFIVFKLVGFYVKVEYRTSRGRIDLVLQTD
                     HYIYIMEFKLDGTTEEAMRQIEEKQYALPFASDERKLFKIGVNFDNETRNIAGWSVD"
     CDS             complement(6790..7386)
                     /locus_tag="ctg92_6"
                     /transl_table=11
                     /translation="VVVVCNVLVAGCASGKVFDRVEKIPHRKVGLLLGTAPVTPWGTKN
                     LYFTYRIDAAVKLFHAKKVDYFIVSGDNHSTDYDEPTCMRDSLVACGVPDERIISDYVG
                     FRTLDLEVRCKAIFGQDSVTVISQSFHNERAIYLAGHNQIDAIAFNAQDVTSVWTTWLR
                     GHSRELLARVKIFIDLIIGKQPRFWGEKVKIPEIR"
     CDS             complement(7908..9116)
                     /locus_tag="ctg92_7"
                     /transl_table=11
                     /translation="MEKLDDMKLTVLYIEYRNFFIDVLSRFYGFEKYDIYHYSEILNVD
                     ELCRNEALNWDMYLIEFWGKEKINWEYLSGNKCLSWTADLFDKYYDYWEWDILSSNEGI
                     FWNELLLNKYKSKLNWNLLSLNKSLPWSIDFINRYVDRLNWVNLSANLSLPWSDYLLEY
                     YENLWDWNLISANPSLPWTDDLIIKYMDRLNWAGLSMNPALPWSSEFIQKYKYNWIWGY
                     SSDWVMTDDIGLCGNSGIHWNEELIEMFDGFIDWGELSLNTGDMWNECLIDKYLCKLHW
                     EECWCPPLGMGGLSSNPSLPWSLDFVDKYKPYLNIKEICSNMSFPWREEDFRNNNGGII
                     NDCDKSYWKLLSMNEGLPWSVGVLYDNRCWFDWNLMKGNVKVYDNCLSVLEKEKMKFLL
                     ELV"
     CDS             complement(10158..11678)
                     /locus_tag="ctg92_8"
                     /transl_table=11
                     /translation="MKGRSELLLIGPSYIRKIRMKKQFIYFLSLFVMCLAACSNPVDPT
                     ALNLDSANINRLIPFRGELNNGVKQLYPEEPYKAFWAENWKTPEQSISWKVNTDGEDYM
                     AEMIVSVNRMGDGEETELVLSNGTDSVICRINTTGWQRCRFPRPLHFNKGTSVLSLKIG
                     KPGKQDDFNVYLYSLEVTRPETYEQLRAEATSLRSNTSWMADLPYGFFFHWNSKSMPQS
                     GEPLAYEDAVNNFDVDRFARTVYECGGKLIFFTTSWAEYYFPAPIQAIDSILPGRTTKR
                     DLVADLSDALGKYGIRLILYYHVGHGDKEWWDKQHYTRDNAGDLFTNVEKIVGEISQRY
                     GNRLAGLWMDDGIGYYPNGASFEKIAKAAKSGNKELAICFNSWILPKLTDFQDYYAGEL
                     GLSLASAGVNDPSLPLDGDGLFHGGPQDGLQATFSGTLEPGDWTHIYKDSIIGDPVLSI
                     DELTQVVKESNKRKNLPMINVRIYQDGTISPKSYALLKELNNRISKGE"
     CDS             complement(11693..13135)
                     /locus_tag="ctg92_9"
                     /transl_table=11
                     /translation="MKRMKTLIKNILLAVPVILSASCSDWLEEDPKTFISPSSFYQTVE
                     DFDGALKGLYPQGQNLNLTEVFADYNDKPESAEQVGDIWANNPGYGFYAFRNAWSGPYS
                     TIKNANMILESIEDKDFTAETKNRIIGEAKCLRAWSYFTLVQFFGDVPLRDKVVTSDAD
                     VAIDRTPQADIYQFIFDDILDAEQKLPEEAQDMGRVNKWVVKAIMARIYLTSAGFPMNQ
                     KENYAKAKEKALEVINSGQYSLMPTFDKVFKTERYTAETIWAQLFSAPDSYSGMHNESS
                     PIGSQTALYLPTDAFIASFDKGDMRKEWGIKPEYVNAKGNKVIARTYYNKYINEEYLEQ
                     ELPASNTNILTWQTQLIRLAEMYLIAAEAENEINGPAGAYQYINAIRKRARVDQNDPTN
                     VPDLSGLSQDQFREAVLLERQHELYEEGFAWYDLKRTQTFDKVQKARGSRLNVPIGAYN
                     NTWLIPDTEILNNNIPQNPDYR"
ORIGIN
        1 tatttatcga gggatacttc ctggttatgg agagtcagct ccatcccata ctttccttcg
       61 gactgataag ctatttcgaa acggcttatc tctttttctc ggaacagact gatatcgaac
      121 aagtcgagca ggtgttccat gtatttgata ctgttcaggt ggccgtttac gtccaggtca
      181 ctatacttca cacggtaagg ttcgccggaa gtgttgtttt ccaccggagc aattttaccc
      241 ggtttttcaa tcggacaggg acggtcggtg atataagcac tcaggccctc cacatcgagc
      301 aaggtcgggc ggcgggtttc catatcgata gccgcccaga tagagcgggc aaagccaaag
      361 gtcttgcctt cgccgttcac cagttcaaag caacggctgg taaacaactt accgacctca
      421 tccacccagg tatataaagt tacggattca gacatggcag gataagaagt catctcgata
      481 gccagacggg aaagaaccca ggcggtatgc ctttcggtca tatcgttata tccgaatcca
      541 cggtcggcgg catggcaaga agcagcatgc aacaaataag ttccgatcat agggattgta
      601 atacgtcccc ggaagtccgt cagataagac tctgttacga aatgaaattc tcctactttg
      661 ttcttctcca taatttactt tatttacaaa atgtttcctt attattctca gacatgtttt
      721 tcctgcaact tcttttccat tgcagataac atgtcgctca gacgttctac cttactcttc
      781 gttatagcaa nnnnnnnnnn nnnnnnnnnn nnnnngataa attgcaggac accgatcgtc
      841 tcactcaatt ctttaaacaa agcctgtgtc tcatcataat gaccactctt ttccaacacc
      901 acacaatcct cattcatttc aaggatacgg gcattgtact tacggatcag atcctcaacc
      961 gtccccatct tgataaagag ttcggtactc agtttataaa gagcgatttc ctggtaaacc
     1021 aggtcttcat ccgtattata ataggctttc aggatatcca cacgcttgtc gatctgtttt
     1081 acgaccttgt cgatcgtatc ctcgtcggca aaggtagtaa ttgtaaactt atgtattccc
     1141 tttatagcag agggagaaac agaaagcgtc tcaatgttca gttgccggcg cgtaaagata
     1201 acagttatct gattcagaag accaacagtg ttttccgaaa agataataac ggtatataat
     1261 tgttttgtat tcatagtttc tcctccttac ttatcaccca aaatcatgtt tgtcacgctt
     1321 cctccggccg gaaccatcgg atataccata ccacaagttt ccacattggc aaccaacata
     1381 taggcaccat cgtgattcaa catttcagca atcgcctcat ccaagtcttc ccgtttatct
     1441 accgcacggg aagcaatacc aaaagccttg gctatcgcta caaaatccgg attcttcatg
     1501 atggtattcg aataccgttc gttgaagaac agctcctgcc actggcgtac cattcccagg
     1561 aaattgttgt taagaacgat gatctttaca ttcagatttt cctgcatgat agttcccaac
     1621 tcctggatag tcatctggat accaccgtcg ccggtaaaga aacagaccgt acggtcaggc
     1681 gctcccagct tcgctccaat ggcggcggga aggccaaagc ccatcgttcc caaacctcct
     1741 gaagtaacta cgctgcgtgt ttgtttatat ttgaaatagc gaacacccat catctggttc
     1801 tgacctacat ccgtaaccag aatcgcatca ttatcggttg cttcggaaac cttacggact
     1861 acttcgccca ttttcagttg gccttcggta ggatagagtt ctttttctat taccttatta
     1921 tattcctctt tttcatccgg ttcgaattca gcattccatt ccggacgctt ccgttcttcc
     1981 agtaaagccg taatcatcgg aatcgtatgc ttggcatttc ccagcacttt cacgtcgacc
     2041 ggcacattct ttccgatctc cgaattgtcg atatccaggt ggataatctt tgcctgcttg
     2101 gcataagtct tcaggtcgcc ggttacgcga tcatcgaaac gcataccgat agcaatcagc
     2161 acgtcacatt cgtttgtctt gcggttcggt ccgacatttc catgcatccc caacatacct
     2221 ttatttaatg ggaagtccga aggtaatgca gacaagccca atacggtaga accggctggt
     2281 atatcgtttt tcaacaagaa ttctttcagt tcttcttcag ctcctcccag gataaccccc
     2341 tgccctacca gacagaatgg ctttttggca ttatttatca atgaagcagc cgcctcgata
     2401 cgttcctccc tgatatccgg ttcaggttgg taactacgaa cataatccac tttctgatac
     2461 tcataatcta ccaaacccac ctgtgcatct ttcgccaaat ccagtaccac aggtcccggg
     2521 cgaccggtcg atgcgatata gaaagcacgg gaaacggccc aagcaatttc ttccgggcgg
     2581 cgtatctggt aagcccattt ggtaatcggt tgtgtgatac cgatcacatc aacttcctgg
     2641 aaagcatctg ttccaagcag cggagacgga acctggccgg caatcaccac catcggtgta
     2701 ctgtccatca gcgcatcggc aataccagtg atggtattgg ttgccccggg acccgaagta
     2761 accaccgtta ctcccacttt tccggaaaca cgggcatatc cctgtgcagc atgtgttgca
     2821 ccttgttcgt ggcgcaccag aatatgtttt aactgatctc tgtaatcgta taaactatcg
     2881 taaattggta tcgcctgccc acccggataa ccgaagatag tatctactcc ttcagcgatc
     2941 agcgctttca gcaaagcttc cgaaccggtt atcttttgtt tgtccatctc taaaatatag
     3001 tatttggtgt ttattaatct tctactattc gtacaccgcc cttatcggcc gaagcaacca
     3061 tctttgcata tgctttcagt gctttcgata ccgtacgttg gcggaaagga ggtgtaaagg
     3121 cttttgttcc gcgggcttct tccgcttcac ggcgtttggc cagttcttcg tctgtcacct
     3181 ttacatgtat ggttctttcg ggaatattaa tttcgataat atcgccgtct ttcactaagc
     3241 caatcgctcc gcctgcagcc gcttcgggag aaatatgtcc gattgacaaa cccgatgttc
     3301 caccgctgaa gcgtccgtct gtgattaacg cacattcttt acccagatgt ttactcttta
     3361 tataagaggt aggatacaac atttcctgca tacccggacc acccttagga ccttcatagg
     3421 tgataacgac gacatcgccg gagacgactt gatctttcag gataccttcg caagcggcat
     3481 cctgcgaatc gaatactttg gcagggccgg caaaacggaa gatactttca tctaccccgg
     3541 ctgttttaac cacacaaccg tcctgtgcaa tatttccata cagaacagcc agaccgccgt
     3601 ctttcacata agcatgttcc acatcgcgga tacatccggt tgcacggtcg gtatccagtt
     3661 ctttataata actttcctgc gatccgagca ccagattgaa acggtgggcc ggagcacttt
     3721 tataaatatt gattgcttct tccgttacat ttacagaggt aatgcagtat tggtcgatag
     3781 cctcattcaa agtcagacca tccgcacgtt tcacggaacc gtccaccaga ccggctttta
     3841 ccagctcatt cataataccg ataatacctc cggcacggtt cacatcttcc acatgataag
     3901 aacaactcgg agccacttta cagataaccg gtgttttgcg tgaaagcata tcgatgtctt
     3961 tcattgtaaa atcgacttcc gcttcatgag ccacggccaa caggtgaagg actgtattcg
     4021 tcgatccccc catggcaata tccagcgaca tagcattcag aaaggcctga cgggtggcaa
     4081 tactgcgagg caatacggaa tcatcgccgt cacgataata tttaaaggca ttatcaacaa
     4141 tcatcttcgc ggcttttttg aacaggcggg tacggttggc atgtgttgca acaactgttc
     4201 cgttgccggg aagagccaat ccaatcgctt cgttcagaca gttcatagag ttagccgtga
     4261 acataccaga acagcaaccg caggtcgggc aagcggaacg ttccaccttt tctacttgtt
     4321 catcgctgat agaatcgtca gccgcttcaa tcatggcgtc gatcaaatcg agtgcacgtc
     4381 cgtccagatt accggcttcc atcggaccgc cggatacaaa gattgtcgga atattcagac
     4441 gcatactggc catcagcata cccggagtaa tcttgtcgca gttactgata caaaccattg
     4501 catcagcctt atgcgcattc accatatatt ccacactgtc agcaatgatg tcgcgggaag
     4561 gcagagaata aagcattccg tcgtgtccca tagcaatacc gtcatcaata gcgatcgtat
     4621 taaattctgc ggcaaagcaa ccgagctttt cgatttccgc ttttacctgc tgtccgatct
     4681 cgtgtagatg cacatggccc ggtacaaact gggtaaatga attcacaatg gcaatgatcg
     4741 gtttaccgaa ctgttcttct ttcatgccgt tggcacgcca taatgcacgg gctccggcca
     4801 tacgtctgcc ttctgtgcta taggagcttc ttaacggatt cttcatcata tctgttttta
     4861 tcttttagtc aataaaaaag cccttctcta tatggagaaa ggcttaagaa atatctttta
     4921 cgacttcaca acttcttaca cacctttctc cttacctact aatgactaga aggaccacca
     4981 cgagaataat atgtaataca ttgttcatca tcttttctta tcgtctttat tttgtttgac
     5041 gctgcaaatg tagaataata atttgtacga gcaaaggatt taaaagaaaa atcttacttt
     5101 ttctttcatt tatcaataaa agagggcggt tcatcttgca ttttaacagt attattaaaa
     5161 tctacatcaa tcgaccgacc aaccggctat gttccgtgtt tcattatcaa agttcacccc
     5221 tatcttaaaa agtttccgtt catccgaggc aaaaggcaag gcatactgct tctcttcgat
     5281 ctgcctcatc gcctcctctg tcgtgccatc caacttaaac tccattatat aaatgtaatg
     5341 atcggtttgc aacaccaggt caatgcgacc acgggaagta cgatattcca ccttcacata
     5401 gaaaccgacc agtttgaaga cgatgaacag gacgttctgg tagtgcactt ccagatttcg
     5461 aatcaattca tatggcgtat cggcaaaaaa actttgcaac cggctaagga aagcatccac
     5521 atccccagac tcgatttctt taatgaattt aaaaagctgg aaggaagtat caataacatt
     5581 gacagaagtg taatatggaa gcaaataatt cagaaacccc tcttctactt cctgatttgg
     5641 aaagcccaat gtatatattt taaatctagg attataggat ttgatcgtca aataaccact
     5701 ttggtaaata accggtatcg ggttacgcga aacggcatcg atactgttca acacatctgc
     5761 attcgtttcc gtatgtgcca tattgtacaa gtcatagtcg gtatgcttca acagctcgac
     5821 caagtaagag ggggtacctg tctcaaacca gtaatctcca aagtcagact tcgcaaatgt
     5881 gtttaacaaa ctgaacggat tgtacatgcc ttgcgaccta tgagtaaaat gataaccatc
     5941 ataacggcgt ttcaattcca tgcaaacttc ttcataatcc atttgcagat tacgagtcaa
     6001 atccaacacc ccttgttcca tatacgcatg gatttccgtc tcggtcatac cacaaatctc
     6061 aacataacga tcatccatcg aaatatccat caaattgttc aaatcactga acacacttac
     6121 tttaccgaac tttgtcacac ctgtcagcaa agcaaaacgg atatcaccgt ccatcgtctt
     6181 caacacccca taaaacggtt ttaatataga acggtattca tcctgcaaca gctcatcccc
     6241 aatagcctgc aacaaaggtt tgtcgtattc atccaccaaa atgaccacac gccttcccga
     6301 tcgagctttt gcccggcgga tcacccctat aaaacgatcg gacaaagtct tttcccgttc
     6361 atcttttccc catgtatctt cccacaggtt caaatgacgt tgcaaaatac tatccaagga
     6421 cgaagcctcc gaatacctct ccgcatttaa atccaaatgc aatatcggat actccaacca
     6481 atcctgttcc agcttctcca tcgccaatcc ctcgaacaac tcctccttac cctgaaaata
     6541 ggcctccaaa gtcgaaacca acaacgattt gccgaaacgg cgcggacgac tcaggaagta
     6601 ataactcccg gtcttcacca tttgataaat caacgctgtt ttatcaacat agagataccc
     6661 ctccttacga atcttctcga aattttgtat gccaatagga taaagtgcag ccataaaccg
     6721 tttttatatt atctatcaag acaaaggtaa cttatttttt atcaataagt atcttattat
     6781 attacatttt catcggattt ccggaatctt gaccttctcc ccccaaaaac ggggttgctt
     6841 accaataatc aagtctataa atattttaac ccgagccaaa agctcacgac tatgtcccct
     6901 caaccaggtt gtccacacag aagtcacatc ttgggcattg aatgcaatcg catctatttg
     6961 attatgaccc gccaaataga tcgcacgctc gttatgaaaa gactgcgaaa taacagtaac
     7021 gctatcctgt ccaaaaatgg ctttacatcg cacttccaaa tcaagcgttc gaaaaccgac
     7081 ataatccgaa ataattcgct catccggtac accacaggca actaacgaat cacgcataca
     7141 agtcggctca tcataatctg ttgaatgatt atcaccactt acaataaagt aatcaacctt
     7201 ttttgcatga aacaatttga ctgccgcatc aatacgatac gtaaaataaa gatttttcgt
     7261 tccccaagga gtaaccggag cagtccccaa caacaaaccg actttacgat gtggtatctt
     7321 ttccaccctg tcaaatacct tacctgaggc acaacctgcc accaacacgt tacaaactac
     7381 aaccactatg tttatgacag aaatgagcag aaataatggt taattgtatg attttcttct
     7441 tactttgaat tacttttttt cacagacttg ctcttttatt ataaaggatt gtcaccaaca
     7501 aaataacaat cctaataaaa caatctattt cttcttagga atatttttgt aaaaggcata
     7561 tagcaaaggt attatttcca gacatatcca aagccataag catgtcatat ttcatttgac
     7621 aggaaagctt ccgtcttcac caatcattac cggataaaac atatcatccc tgcaaagaac
     7681 gattgctcca acctatcaga gtaatataaa ttttgcagac tgtattaact aataatattt
     7741 tcactgtccc caaaatacga tgtcatattt ttcaacacac gatctttact tgtattagca
     7801 tagcaataga cttttctata aaatataggc gcatattctt ttcttcagct tcgtcactta
     7861 tataactatc ctacccaatc atccacgacc attttttgat acttcaatca aactaattca
     7921 agtaaaaatt tcatcttttc tttttctaaa acacttaaac agttatcgta tactttcaca
     7981 tttcctttca ttagattcca atcaaaccaa catctattat catatagtac tcctacagac
     8041 caaggtaaac cttcattcat actcaataat ttccagtaag atttatcaca atcatttatt
     8101 attccaccat tattatttct aaaatcctct tcacgccaag ggaaagacat attagaacaa
     8161 atttctttta tatttaaata aggtttatat ttatccacaa agtccaagct ccaaggcaat
     8221 gaaggattac tactgagacc tcccataccc aaaggaggac accagcattc ttcccaatgc
     8281 aatttacata aatatttatc aatcaaacat tcattccaca tatctcctgt atttaaacta
     8341 agctctcccc aatcaataaa accatcaaac atctctatca attcctcatt ccagtgaata
     8401 cccgaattgc cacataaacc tatatcatcg gtcattaccc aatctgatga atatccccag
     8461 atccagttat atttatactt ttgtataaac tcagaactcc aaggtaacgc tggattcata
     8521 cttaatccag cccaatttaa acgatccata tatttaatga ttaaatcatc agtccaaggc
     8581 aacgatggat tggcacttat caagttccaa tcccataaat tctcataata ttccaacaaa
     8641 tagtcagacc aaggcaatga cagattagca cttaaattaa cccaatttaa tctatcaaca
     8701 tagcgattta taaaatcaat tgaccacggt aacgatttat ttaagctcaa caaattccaa
     8761 tttaacttag atttatactt attaagcagc aactcattcc agaatattcc ctcattagaa
     8821 gacaagatat cccattccca ataatcataa tatttatcaa aaagatctgc tgtccatgac
     8881 aaacacttat ttccactcaa atattcccaa ttaatttttt ctttacccca aaattctatc
     8941 agatacatat cccaatttaa agcttcattt ctacacaatt catcaacatt caaaatttca
     9001 ctataatgat atatatcata tttttcaaaa ccataaaatc tacttaatac atcaataaaa
     9061 aaatttctat attcaatata taatacagtt aatttcatat catccaactt ttccataata
     9121 attagagcct gtttaaattt cacagtttga aataaataaa gtgtttcctc tttctgctaa
     9181 aataattatt tttaattact aagtttcaaa taattatgta ttgtacggat ttagaagaaa
     9241 cacagtggca agttatcaag aaaatcttga acttgcaaga aagaaagcga aaatacaggg
     9301 caaccgcacc aaaatagttc tcgcccgaaa gaaaacggat ggggaaatgt tctttttttg
     9361 ataagtgcca tttttgccaa cacaaaacac cgttttacat aattgaaatg gtagtttaaa
     9421 atcaatgaga aagtccgcga cggaaacaat cttccccctc catggttttc atacctctgc
     9481 cttcacactc gtaacacact gtattatatc cttttgtggt gaaaccagcc ttttcactat
     9541 tgtttttgga accgtaacag gaacccttcc gatgagtagg catctgtggg gaaatagata
     9601 gttatctatg tggacacgga tagttatccg ttggggaaga accactcgtc ttcacacagt
     9661 catgtgagta gtgctgacac tacgatgccg gccggatggg atagcagtac cggtatgacg
     9721 gtacacctac cctataacgt acataccaat agggtatagg gtaccggacg ctactttaca
     9781 gggtataatc tgccggacta taggggaaaa tcgtacgtat tcttgggaaa agacgtacgc
     9841 ttttgttcga acaatatttt atctcccttc acagcaaaca actgtcctat aatatgttac
     9901 aaacactgaa agatgaaatc aaatttataa aactccattg ggagattgat tttttcccct
     9961 aaaaacgaga aggtgtgtca aaacactatt accgaacgca gacggagcgc agacaataat
    10021 tattttttaa taaaagtttg tgcctgtctg cgtgttctga gtcgttagcg ttcagtaatt
    10081 actattttga cacatcaccc aatcaattga attcttattt ctgagcctcc attcgcttca
    10141 tattcgataa tttccggtca ttctccttta ctgatacgat tgttcagttc tttcaacaaa
    10201 gcatacgatt tcggagaaat cgttccatcc tgataaatcc ggacattaat catcggaaga
    10261 ttttttcgtt tgttagattc tttcactacc tgcgtcaatt cgtcaatgga aagaacagga
    10321 tcaccgataa tggaatcttt ataaatgtgc gtccagtcac ccggctccaa tgttccggag
    10381 aaagttgcct gtaagccatc ctgagggcca ccgtgaaaca atccgtcccc atccaacgga
    10441 agagaaggat cgttaacacc ggcactggcc aaagacaaac ccagttcgcc agcataataa
    10501 tcctgaaagt ccgtcagttt cggcaatatc caggaattaa aacaaatcgc caactcctta
    10561 tttccacttt tggcggcttt agcaatcttt tcaaacgaag cgccgttagg ataataaccg
    10621 ataccgtcat ccatccacaa accggccaga cgatttccat accgctggct aatctctccc
    10681 actatctttt ccacatttgt aaacaaatct cctgcattat cacgtgtata atgctgcttg
    10741 tcccaccatt ctttatctcc atgaccgaca tggtaataca gaatcagacg aatgccgtat
    10801 ttacccaacg catcagataa atcagccact aaatctctct ttgtggtacg ccccggcaaa
    10861 atagaatcga ttgcctgtat cggagccggg aaataatatt ccgcccacga cgttgtaaaa
    10921 aatatcaact tcccgccaca ttcgtaaaca gttcgtgcaa agcggtccac atcaaagtta
    10981 ttgaccgcat cctcataggc taacggctct cctgactgag gcatactctt tgaattccag
    11041 tggaagaaaa agccataagg caaatccgcc atccaggatg tattactgcg aagtgatgta
    11101 gcttccgccc gcagctgctc ataagtctcc ggccgggtga cttccaacga gtacagatac
    11161 acattaaaat catcctgctt accgggtttg ccaatcttta aagataaaac ggaagtcccc
    11221 ttattaaaat gtaaaggacg ggggaaccgg caacgctgcc atccggttgt atttatccgg
    11281 caaataacac tgtccgttcc attggataat accaactccg tttcttcccc atctcccatc
    11341 cggttgacag aaacgatcat ttcagccatg tagtcttcac cgtccgtatt gactttccag
    11401 gatattgact gctcgggagt tttccagttc tccgcccaga atgctttata aggttcttcc
    11461 ggataaagtt gtttcacacc attattcagt tctccacgaa aaggaatcaa ccggtttatg
    11521 ttcgccgaat ccaggtttaa tgccgtcgga tcaaccggat tactgcaagc ggccagacac
    11581 ataacaaaca aagacaaaaa ataaataaat tgctttttca ttcgtatttt acggatatag
    11641 gaagggccaa tcaataataa ctcagaccgg cccttcatgt attctacatt aattatctgt
    11701 aatccggatt ctgaggtatg ttgttattca gaatttcggt atcaggaatc aaccaagtat
    11761 tgttgtaagc accgatgggg acattcaatc tgctgccacg cgctttctgt accttatcga
    11821 atgtctgggt acgtttcaaa tcgtaccagg caaaaccctc ttcatacaat tcatgctgac
    11881 gttccagcag aacggcttca cggaactggt cctgagaaag tccgctcaag tcaggcacgt
    11941 ttgtcgggtc gttctggtcg acacgggcac gtttacggat agcattgata tattgataag
    12001 caccggccgg tccgtttatc tcattttcag cttcggcggc aatcagatac atttcagcca
    12061 aacgaatcaa ttgagtctgc caggtcaaaa tattggtatt agatgctggc aactcctgtt
    12121 ccagatactc ttcattgata tacttattat aatatgtacg cgcgatgact ttatttcctt
    12181 tcgcatttac atattcaggt ttaattcccc attctttacg catatcacct ttatcgaagc
    12241 tggcgataaa agcatctgtc ggaagataca aggctgtctg gctgccaatc ggtgaagatt
    12301 cattatgcat accgctatag ctatcgggag cggaaaacaa ctgagcccag atagtttcag
    12361 ccgtataacg ttccgtctta aagactttat cgaaggtagg catcaaagaa tactgaccgc
    12421 tgttgattac ttcaagcgct ttctctttgg ctttcgcata attttctttc tgattcatcg
    12481 ggaagccggc tgatgtcaga tagatacgtg ccataatcgc ttttacgacc catttattta
    12541 cacgtcccat atcctgcgct tcttccggaa gtttttgttc cgcatccaga atatcgtcaa
    12601 aaataaactg atagatatca gcctgcggcg tacggtctat tgccacgtcg gcatcactgg
    12661 tcacgacttt atcccgcaaa gggacatctc caaagaactg gaccaatgta aaataagacc
    12721 aggcacgcaa acatttcgcc tcaccgataa tacgattctt ggtttcggca gtaaaatcct
    12781 tatcttctat cgactccaat atcatattcg cattctttat cgtactgtat gggccggacc
    12841 aggcatttct aaaggcataa aaaccatatc ccggattatt tgcccagata tccccgacct
    12901 gttcagccga ttcaggctta tcattatagt cggcaaaaac ttccgtcaga ttcagatttt
    12961 gtccctgagg atataaccct ttcaaagctc cgtcaaaatc ttccaccgtt tgatagaagg
    13021 aagagggaga aataaatgtt ttcgggtctt cttccagcca atcggagcaa gaagcagaca
    13081 gaataaccgg tacagccagc aatatatttt taatcagtgt tttcattctt ttcatacgta
    13141 ttaaaattta acctgtaaac ccaaagtaaa tgatttcgca gacgggtaaa cccctctgtc
    13201 ccatccgttc acggcagaag acgtccagga tgcttccggg tcataatgag aatagcttgt
    13261 aatcgtaatc agattctgtc cgctcagata aaccgagata ttaggtttac gggaacccgc
    13321 gaaccattga gacggcaacg tataagccag tttgatatct ttgaatcgca gatacgaacc
    13381 gttttccacc caaaccgaac tcgggtcacc gaaggccaga taatccttgg tcgcaacaga
    13441 agcacgtgca tatttggcat tcggattttc aggagtccaa tggttttccc agacatcttt
    13501 gcggatattc catgtgccac cgatattagt gatactttta ttaaattcat taacgatatc
    13561 accaccaaca ctacctatta acaggaatga taactcgaag ttattccaat tgataatatt
    13621 cgtcagaccg aaagtaaact taggctgcgt atttgcaata atcgttttat cacctgttgt
    13681 aataccagct ttcccgtccg tgtctttata ccggtaatca cctgctttct tggttgcttc
    13741 gccattcaaa cgagcttctt catccgtctg ataaatacct tctatttcgt agccatacaa
    13801 ttggaacgga gctttaccga caaacagagg gaaccagttt ccgccaccga taggagcatc
    13861 tatccgctga atcttatttc catacacatc cgaacccaaa tctttcacga ttgatctatt
    13921 ggatgtaata ttcaaattag tcgtccagtt cacttttcct ttcatattga ttgtattgat
    13981 agatatttca aaacctttat tatcaatacg tcctaagttt ctcagcatag aagaatatcc
    14041 ggaagacggg ggaagagtcg cattatacag caaatcgcgc gtttgtttcc aataatagtc
    14101 aaaaccgata ttcaggcggt tggaaaagaa tccgaagtcg acacctatat ccgtttgtgt
    14161 agttgtttcc catttcaagt cgtcgtttgc catggaggat aaaccgaaac caatatcttt
    14221 tccatcaccg aaaataggac cggaagttcc cagacgggcg aaagtctgat acgggctaat
    14281 agattgatta ccggtctgtc cgatactggc acgcagtttc agattgctca gccaatcaat
    14341 atcttgcata aaattctctt ccgacaaacg ccaggccaat gcggcggaag ggaagaaagc
    14401 gaatttatgg ttcttactga atttagacga accgtcatat cgtgcggtga cagtcaacag
    14461 atatctttcc atcaggttat aattggcacg tcccaggaaa gaagccatcc ggtaatcgct
    14521 gtaaccggaa gacggagttc cgggtgtaga agctactccc aaattattcg tttcatagac
    14581 atcgcgcaga aatcctgtac ctgagccgcc caaatcatta tactgatagg tctggaaagt
    14641 aacaccaccc atcaggttca atgcatgatt cttattgaac cgcttgtcgt aggtcaaaat
    14701 attctcatta ataatagtat aataattaga ttttgactta gacgcatcac catccaattt
    14761 acctccggca gacaaaccaa tcggaatgta ccggtcggaa ctacccgcat tgacttcagc
    14821 accggcattc acccggaaag tcaatccgt
//
