LOCUS       c00119_gnlPro..        14409 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JADJOCNO_119.
ACCESSION   c00119_gnlPro..
VERSION     c00119_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 12:54:34
            Original ID  :: gnl|Prokka|JADJOCNO_119
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14409
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..1491
                     /locus_tag="ctg119_1"
                     /transl_table=11
                     /translation="GLSLVSIEQARLNMDTELAPLQYDFDRVVAQTRNKWNELLGRIEI
                     EGTNEVDKTKFYTNLYRAYAGKQTWNDVNGQYRDACENIQQLDHGNMYGGDAFWNSFWN
                     LNGLWSIISPRIVDDWVTTQLEMFKHTGWTSKGPAGLEYSGIMEGSHETALMVAAYQKG
                     IRKDGEAIYEAVLKNVTETGIDHPCGGSCGNPLLDVYIKQGYMPMEKGVVSKTLDYAYD
                     DWCVSQLALALGKKKEGKALLARSMNYKNVFHPEKKFVMRRDSLGNWDPDFDVFSNKGF
                     IEGNSWQYSWYVPHDIPGLVDFLGKDLFNSRLEEGFIKSEKHKFAAHVFDRTTGQSAEF
                     YINQGNEVNMCTPFLFNYSGKPWLAQKWSRAILDSFYGSTPYHGWEGDEDEGQMGGWYV
                     MSALGLFEMNGGVSLKPELELSSPLFNKITIRLDPGYYKGKTFTIEARNNSKENIYIQK
                     AYLNGKELKQPRIPFAAIVSGGTLLLEMGDKPKFDCFN"
     protocluster    1..14409
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4286:7144]"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      4287..7144
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
     cand_cluster    1..14409
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Fer4_7 and TPP_enzyme_C and POR and
                     POR_N and PFOR_II and not (EKR or Fer4_16))"
                     /kind="single"
                     /product="porA"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14409
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="porA"
                     /region_number="1"
                     /rules="(Fer4_7 and TPP_enzyme_C and POR and POR_N and
                     PFOR_II and not (EKR or Fer4_16))"
                     /tool="gutsmash"
     CDS             1532..2776
                     /locus_tag="ctg119_2"
                     /transl_table=11
                     /translation="MPLFKKDEQPRQPNLEQLLSEFNRSLTLIVDKSLLIGNIVAKVKQ
                     ICPVESVYIFLLDENTGKFKLQNEAKNKPVTLTNRSRLISWLSVNEKHLIISRHPDIVS
                     YFPPEEQEIIRQLGAELIFPLKIMNQINGTIFLGKKTDGAPFTEQELNLLSILINQATF
                     AIEHASLYEQQTERLKKMYRTDRLATLGELAAGAAHEIRNPLTAIRSTIQYLSKDFSAD
                     PVKSEMVTELISEVERINKIVQGLLSFARPSDLNTSDINIEQLINQTLLLVTNTLRKQN
                     VEVEFEYFTDNTTIQGDAEQLKQVFLNIILNAVEAMGKNPPERSRTLIISIEKGTPINT
                     HSRYLIISFEDSGKGIEQKNIENVFNPFFTTKEEGTGLGLAICYGIINRHEGEIEVKSV
                     PDKGTCINIKLPQRI"
     CDS             2828..4147
                     /locus_tag="ctg119_3"
                     /transl_table=11
                     /translation="MIARLLTDEGYDVMPVENGREAVEALLSFQPDVILLDQQMPVLTG
                     VEALEEIRRISPTQVVLFVTAFGSISLAVDAVKKGAYDFIEKPFDNDKLLLTVKRAVEH
                     SRMKGEISTLKKTLGEKRSNVIGENTGLKQVMAQVLRVAETNATVLIHGESGTGKELIA
                     RAVHHNSLRANGPFVAINCGAIPLTLMESELFGHERGAFTDAKEAKAGTFERANGGTLF
                     LDEVGELPLDAQVKLLRVLEERKITRIGGKKAIPVDVRIVAATNRNLDDEVKGGHFRLD
                     LLYRLNVFTLILPPLRERKEDIPLLANFFIRKYNQALSLDVQSITPEAVKLLSSYDWPG
                     NVRDLENALQSAMILCTDGTIRPEHLPDRVKGYDSTEEATIAGSGGSIREINAQMEKEL
                     ILEALKKHNFNRTLTAEALAISRKTLFNKMKRYGLSTDEI"
     CDS             4287..4514
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg119_4"
                     /sec_met_domain="Fer4_7 (E-value: 1.8e-14, bitscore: 44.0,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 6.4e-08, bitscore: 22.2,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 1.1e-08, bitscore: 24.7,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6e-07, bitscore: 19.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKIKGAVVVNQERCKGCNLCVVACPSDVLELHPREVNNKGYHYV
                     YMKNPDACIGCASCGLVCPDGCLTIYKVKI"
     CDS             4522..5607
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     PFOR_II"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg119_5"
                     /sec_met_domain="PFOR_II (E-value: 3.5e-29, bitscore: 91.0,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7.2e-48, bitscore: 153.1,
                     seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEEIKLMKGNEAIAHAAIRYGADGYFGYPITPQSEILETLMAEM
                     PWETTGMVVLQAESEVAAINMVYGGAGTGKRVLTSSSSPGVSLKQEGVSYIAGAELPCL
                     IVNVMRGGPGLGTIQPSQADYFQTVKGGGHGDYRLITLAPSSVQEMADFVGLGFDLAFK
                     YCNPAIILADGIIGQMMEKVVMPPFRPRKTETEIIAECPWAAQGKLKSRKANVITSLEL
                     DPAKMEENNLRFQAKYRKIEENEVRYEEFHCDDAEYLLVAFGSSARICQKVVEIARAEG
                     IKLGLLRPITLWPFPKKAIADYAEKVKGMLSVELNAGQMVEDIRLAVNGKVKVEHFGRL
                     GGIVFTPDEVLNALKELIIEN"
     CDS             5624..5794
                     /locus_tag="ctg119_6"
                     /transl_table=11
                     /translation="MTRGSKTDSILTILFMVLAAAAIICYFAVDDRHVFLYCGGAAICF
                     RLVQYLLRFIS"
     CDS             5808..6584
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg119_7"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.6e-24, bitscore:
                     76.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNEIIKPENLVYTKPELMNDNPMHYCPGCSHGVIHKLIAEVIA
                     EMGMEEKTIGVSPVGCAVFAYNYXXXXXXIDWEEAAHGRAPAIATAIKRLNPEKMVFTY
                     QGDGDLAAIGTAETIHAANRGENIVIVFVNNAIYGMTGGQMAPTTLEGMPTATCPYGRN
                     IALNGYPLKIGDLLAQLEGTCLVTRQSVQTAAAVRKAKKMLRKAFENSMAGKGTSVVEF
                     VSTCSSGWKMTPEKANKWMEENMFPFYPLGDLKNKE"
     CDS             6602..7144
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg119_8"
                     /sec_met_domain="POR (E-value: 3e-37, bitscore: 118.2,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQEIIIAGFGGQGVLSMGKILAYSGLMEGKEVSWMPSYGPEQRG
                     GTANVTVILSDDPISSPILNEYDIAIILNQPSMDKFESKVKPGGILIYDGYGIHTPVKR
                     TDISVYRVDAMDAATEMKNEKAFNMLILGGLLKIVPMVKLENVLLGLKKSLPERHHKLI
                     PMNEAAIKKGMEIIQKM"
     CDS             7215..9350
                     /locus_tag="ctg119_9"
                     /transl_table=11
                     /translation="MKHCLYILLLLIVSATTVQAQRGASRADQKGGGKRGGFSLSNLTS
                     SQKDIPDSLLVADSAALNSKRITAYRLTPSLGEAYVAPLDTNKLNFSNSTLVESKSLAI
                     GYLANLGAPAQTKIFSERQEARDFIFADAYDYYITTPENAYFYNTKIPYTNVLYTTAGG
                     STNKEEQLKGTMTMNFGKKINVGADIDYIYGRGHYKNNGNKLLSYRFFGSYQTDRYEMH
                     AYLSNFNFVNYENGGMANDSTISHPDEYFPEGRPSDTKSYDIRYLTNAWNRVRGKRYFL
                     TQRYNLGFTRELEEEDEEGNPKEMFVPVSSIIHTIDYEDNRRRFIADNTALMDSSYIVD
                     DNGLRFPRIYGLGATLNDQTSSWNLKNTIGLSLREGFQDWVKFGLTAFVRLEKRRFKLE
                     PRIEGLDYGEYGRGPYFSVDNIDLKNLPTAKLYDEFSTYVGAELSKRQGSILTYNARGE
                     LCMVGSDVGEFRVTGDLQTRFKLFNKDAVIKADAYIKNVTPAFYMRHNHSRYYWWDNPN
                     FNMTQQIYAGGEVYLESSKTTLKAGVESIQNYIYFNKQGFPVQHGSNLQVVSARIKQDF
                     RFRAFGWENEACWQLSSDESVLPLPSLSAYSNMYLAIKVAKVLTVQLGANVYYNTAYYA
                     PYYEPATQQFQVQDEVKVGNYPLVNAYVNFHLKQARFFVMAYNLSSKFADPNYFSLAHY
                     PLNPMVLKMGIAVTFNN"
     CDS             9356..10174
                     /locus_tag="ctg119_10"
                     /transl_table=11
                     /translation="MKSRKLLVVYIVLLACVLIAMFRLWPYKQEPVPPRDYPEIKSEGI
                     LRLVTEYNQSGYYVAGDTIEGFQYELSQAISALSGLEVQTQLEMSLAESFKQLSNNQCD
                     VIARNIPITSDIKEDYLFTDPIVFNKQVLVQRTEEANNGIKPIRNQLDLAQKTLYIPKN
                     SPALLRLQNLAHEIGDTIYVIEDELYSSEQLAIMVAKGDIDYAVCDQQIARVSKGNLPE
                     IDIDTDISFTQLQSWAVRKDSPILLDSLNSWLSQIKESGLYDQIYKRYYK"
     CDS             complement(10185..11327)
                     /locus_tag="ctg119_11"
                     /transl_table=11
                     /translation="MGTDDSCNSSQKKVTLNEPDTVHELLNTILDHLPLGVFVKDPEDH
                     FNYLYWNKFMEEITGIDTSQIEGHDDSEVYYNALMSVEERLEVDKKVISSGKVAEFHGW
                     LKDASGAMKYLEVEKYPISLSNGKPLLLALWRDATVKRAIEKRLEDERDKAEMADKLKS
                     KYLADMSHEIRTPLNAITGFSEMMAFADTDEERMSYYEIIKANNQLLMQLINDILDLSK
                     IEADAIKISYAPIDLNEMMDTTYASVKPRMPKDVKLILEKGLDSCTFGTDYIRLLQLVN
                     NLVNNAIKNTKKGSITMGYKALEDGRLNFYVKDTGQGIAEEQLQNLFNRFVKVNDYVEG
                     IGLGLAICKGLVTKMGGSIRVESQLGEGSTFSFILPSREE"
     CDS             11511..12806
                     /locus_tag="ctg119_12"
                     /transl_table=11
                     /translation="MRFDELDLEEAVLDGLDAMNFQDTTPVQELTIPVILEGKDIIACA
                     QTGTGKTAAYVLPLINQLSKGNHPDNAVNAVIMAPTRELAQQIDQQIEGFTYFVPVSAV
                     AVYGGTDGVAWEQQKRGMEMGADIVIATPGRLLSHLKLGTVDLSQVSYFVLDEADRMLD
                     MGFYDDIMQVYKQLPPTCQTIMFSATMPPKIRTLAKTILKNPEEVKIAISRPPETIMQT
                     AYICYDPQKLKILEDLFLQSRPQRVIIFSSSKMKVKELASTLKRMKFNVAAMHSDLEQS
                     QREEVMKEFKNGHIDILVATDVVSRGIDINDIKLVINYDIPHDPEDYVHRIGRTARGTG
                     GEGLAITFISIEEQAQFKRIEDFLEKEVYKIPIDPKFGETPLYEPEKYGNMRRGRGRPR
                     KDGNNGGRNPGNKRPGGNPKSGNRRGRPRKES"
     CDS             complement(13001..14407)
                     /locus_tag="ctg119_13"
                     /transl_table=11
                     /translation="AAEAPAANEPKRVVFRHPDTKSVLDQLFPFSPSPAKQEKAAPQQP
                     EPQAAPQPQQQNTPRQNNNNRQNNQNNNHNNQRNNNNNNASQEKQYEFDGILIGTGVLE
                     MMQDGYGFLRSSDYNYLTSPDDIYVSQSQIKLFGLKTGDVVEGAIRPPKEGEKYFPLVK
                     VDKINGRSPEEVRDRVPFDHLTPLFPDEKFMLTARKAPKVYDNIAVRVVDLFSPIGKGQ
                     RGLIVAQPKTGKTMLLKDIANAIAANHPEVYMIILLIDERPEEVTDMARSVDAEVIAST
                     FDEPAERHVKIAEIVLNKAKRMVECGHDVVILLDSITRLARAYNTVQPASGKVLSGGVD
                     ANALQKPKRFFGAARNIENGGSLTILATALTETGSKMDDVIFEEFKGTGNMELQLDRKL
                     SNKRIYPAVDITASSTRRDDLLQDESTLNRMWILRKYLSDMNSIEAMEFVKKRMEQTYD
                     NMEFLASMNG"
ORIGIN
        1 ggtttatcgc tggtaagtat cgaacaggca cggctgaata tggacaccga actcgccccc
       61 ttgcaatatg acttcgaccg ggtagtcgcc cagacccgca acaaatggaa cgaactgctc
      121 ggcagaatag aaatagaagg aacgaacgag gtggacaaaa cgaaattcta caccaacctg
      181 taccgtgcct atgccggcaa acaaacatgg aacgatgtga acggccaata tagagacgct
      241 tgtgaaaaca tacaacaact ggatcacgga aatatgtatg gcggcgatgc cttctggaac
      301 agtttctgga atctaaacgg cctctggtcg atcatctccc cccgcatcgt ggacgattgg
      361 gtaaccaccc agctggagat gttcaaacat accggatgga caagcaaagg gccggccgga
      421 ctggaatact ccggcatcat ggaaggttcg cacgaaacag ccctgatggt tgccgcctat
      481 caaaaaggca tacgcaaaga cggtgaagca atctatgaag ccgtgctgaa aaacgtcacg
      541 gaaacaggta tcgaccatcc ctgcggaggc agctgcggta accctctgct ggacgtttat
      601 atcaaacaag ggtatatgcc gatggaaaag ggagtggttt ccaaaacgct cgattatgcg
      661 tacgacgact ggtgcgtctc ccaactggcc ctggcactcg gaaagaaaaa agaaggaaaa
      721 gcgctgctgg cacgttcgat gaattataag aacgtattcc acccggagaa aaagttcgtc
      781 atgcggcgtg acagcctggg taactgggac ccggatttcg atgtgttctc caataaggga
      841 ttcattgaag gcaacagctg gcaatactcc tggtacgtgc cgcacgatat tcccggactg
      901 gtagacttcc tggggaaaga cctcttcaac agccggctgg aagagggatt tatcaaatcg
      961 gaaaagcata agtttgccgc ccatgtattc gaccgtacca caggacagtc ggctgagttt
     1021 tacatcaatc agggaaacga agtaaatatg tgtaccccgt tcctgttcaa ctattccggt
     1081 aaaccctggc tggcccagaa atggtcgcgt gccatcctgg acagtttcta cggctcaacc
     1141 ccttatcatg gttgggaagg cgacgaggat gaaggtcaga tgggcggttg gtacgtgatg
     1201 agcgcactgg gtctgttcga aatgaacgga ggagtttccc tgaagccgga actggaactg
     1261 agcagcccgc tattcaacaa aataacgatc cgtctggacc ccggttatta taaagggaag
     1321 actttcacga tcgaagcccg caacaactca aaagaaaaca tctatatcca aaaggcttat
     1381 ctgaacggaa aagaactgaa acaaccccga ataccattcg ctgccatcgt atccggaggg
     1441 acgttgttgc tcgagatggg agataaaccg aagttcgatt gtttcaatta atacgatttt
     1501 gcgtactttt gcacaaagat caagaaaaag tatgccacta ttcaagaagg acgaacaacc
     1561 cagacaaccg aacctggagc agctactctc ggagtttaac cggtcgctca ctctgatcgt
     1621 cgacaagtca ctgcttatcg gcaatatcgt tgccaaggta aagcaaatat gcccggtaga
     1681 aagtgtttat atcttcctgc tggatgaaaa cacaggcaaa ttcaaactgc agaacgaagc
     1741 gaagaacaag cctgtgacgc tgaccaaccg cagccggctg atcagctggc tgtctgtcaa
     1801 cgaaaagcac ctgatcatct ccaggcatcc ggatatcgtc tcctattttc ctcccgaaga
     1861 acaggaaata atcaggcaac tgggtgccga actgatcttc cccctcaaga tcatgaacca
     1921 gatcaacggt acgatctttt tagggaagaa aaccgatggc gccccattca ccgaacagga
     1981 actgaacctg ctttccatcc tgatcaacca ggctacattc gccatcgaac atgcttcgct
     2041 ttacgagcag cagaccgaac gtctgaaaaa gatgtaccgt accgaccgcc tggcaacact
     2101 cggcgaactg gcagccgggg cggcccatga gatacgtaac ccgctgacag ccatccggag
     2161 cacgatacaa tatctgagca aagacttcag cgccgaccca gtaaaaagcg aaatggtgac
     2221 ggagctgatc tcggaagtgg aacgtatcaa caagatcgta caaggtctgt tgtctttcgc
     2281 ccgtccgtct gacctgaaca cgtccgatat aaatatcgaa cagctgatca accagacgct
     2341 tctgctggtg accaatacat tacgtaaaca aaacgtagag gtggaattcg aatatttcac
     2401 cgacaacacg accatccagg gggatgcgga acagctgaaa caggttttcc tgaatatcat
     2461 cctgaatgcc gtcgaagcga tggggaagaa tccgccggaa cgctcgcgta cattaataat
     2521 aagtatagaa aagggaactc ccatcaatac ccattcccgt tacctgatca tctcgttcga
     2581 ggatagcggc aaggggatcg aacagaagaa catcgagaat gtattcaacc ccttcttcac
     2641 gaccaaggaa gaagggaccg gactcgggct cgccatctgc tacggtatca tcaaccgcca
     2701 tgaaggcgag atcgaagtaa aaagcgtgcc ggacaaaggc acttgtataa atataaaatt
     2761 accgcaacgc atatgannnn nnnnnnnnnn nnnnnnnnnn nnngacgacg agccgcgcat
     2821 ccgcaagatg atcgcccgtt tgctgaccga tgaaggatat gatgtaatgc ccgtcgaaaa
     2881 cggacgggag gcggtagagg ctctcctctc cttccagccc gacgttattc tgctggacca
     2941 gcagatgccg gtactgaccg gtgtggaagc attggaggag atcaggcgta tctccccgac
     3001 ccaggttgtc ctttttgtga cagccttcgg ttccatctcc ctcgccgtcg acgctgtgaa
     3061 gaaaggggct tacgacttta tagaaaagcc tttcgacaac gataaattat tactcaccgt
     3121 caaacgtgcc gtcgaacaca gccgcatgaa aggtgaaatc tccaccctga aaaagacact
     3181 gggggaaaaa cgaagcaacg tgatcggcga gaacacagga ctgaaacaag tgatggcaca
     3241 ggtcctgcgg gtagcggaaa ccaatgcgac cgtcctgatc cacggcgaga gcggtacagg
     3301 aaaagaactg atcgcccgtg ccgtccacca caacagcctg cgggcaaacg gtcctttcgt
     3361 tgcgatcaac tgcggcgcca ttcccctgac attgatggaa agcgaactat tcggccatga
     3421 acgcggtgcc tttaccgatg ctaaagaagc aaaggcgggt actttcgagc gggcaaacgg
     3481 cgggacattg tttctcgacg aagtgggaga acttcccctg gatgcacagg ttaaattgct
     3541 ccgtgtgctg gaagagcgga agatcacccg aatcggcgga aagaaagcga taccggtaga
     3601 tgtgcgtatc gtagccgcca ccaaccgtaa tctggacgat gaagtaaaag gcggacattt
     3661 ccgtctcgac ctgttgtatc gtctgaatgt atttaccctg atccttcccc cgctcaggga
     3721 aaggaaagaa gatattcccc tgctggctaa tttctttatc cgtaaataca accaggcgtt
     3781 gagcctcgat gtgcagtcta tcactcccga agcggtaaag ctactctcct cttacgactg
     3841 gcccggcaat gtgcgtgacc tggagaacgc cctgcaaagt gccatgatct tatgcacgga
     3901 cggcacgatc cgccccgaac atttgcccga ccgggtaaaa ggatatgatt cgacggaaga
     3961 agcaaccatc gccggaagcg gaggaagcat ccgcgaaatc aatgcgcaaa tggaaaagga
     4021 actgattctg gaagccctaa agaagcacaa cttcaaccgg acactgacag ccgaggctct
     4081 tgctatcagc cggaaaacgt tgtttaacaa aatgaagcgt tacggactgt ctacagatga
     4141 aatttgacag acagccatta ctattcattg gctatctgtt atcattagag gctaacgact
     4201 attaaaaaac taaacaatcc ttgtttttac aacattagtt cttaactttg ccgacctaca
     4261 cgacataaaa cataattagt tatactatgg caaagataaa aggagcggtc gttgtaaacc
     4321 aggaacgctg caaagggtgc aacttatgtg tagttgcctg ccccagcgat gttctggaat
     4381 tacacccgcg tgaagtgaac aacaaagggt accattatgt gtacatgaaa aacccggatg
     4441 cttgcatcgg ttgcgccagt tgcggattgg tttgtcccga cggctgttta accatctaca
     4501 aagtaaaaat ataaaacaga tatggcagaa gagataaaat taatgaaggg gaacgaagcc
     4561 atcgcccacg cagctatccg ctacggtgcc gacggatact tcggataccc tatcactccg
     4621 caatcggaga tcctggaaac cctgatggct gaaatgccct gggaaactac cggtatggta
     4681 gtactgcaag ctgaaagcga agtggcagcg atcaatatgg tgtatggcgg tgccggaaca
     4741 ggtaaacgtg tattgacttc atcttccagc cccggcgtca gcctgaaaca ggaaggtgtt
     4801 tcctatattg caggggcgga acttccttgt ctgattgtaa acgtcatgcg tggcggtccc
     4861 ggcctgggaa caatccagcc aagccaggca gactacttcc agactgtgaa aggtggcgga
     4921 cacggtgact atcgcctgat taccctggcc ccttcttccg tacaggagat ggcagacttt
     4981 gtcggactgg gtttcgacct tgccttcaaa tattgcaatc cggctattat ccttgccgac
     5041 ggtatcatcg gccagatgat ggaaaaagtg gtgatgcctc ctttccgtcc gcgtaagaca
     5101 gaaactgaaa tcatcgccga atgtccgtgg gccgcacagg gcaaactgaa aagccgcaaa
     5161 gcgaacgtga tcacttcact ggagctcgac ccggccaaaa tggaagagaa caacctccgc
     5221 ttccaggcta aataccgtaa gattgaagaa aacgaagtac gctacgaaga gttccattgc
     5281 gacgatgcgg aatatctgct ggttgccttc ggttcttccg cacgtatttg tcagaaagtt
     5341 gtggagatcg cacgtgccga aggtatcaaa ctcggcctgt tgcgcccgat cacgctgtgg
     5401 ccgttcccga aaaaagccat tgccgattat gccgaaaagg taaaaggcat gctttccgtc
     5461 gaactgaatg ccggccagat ggtggaagat atccgcctgg ctgtaaacgg aaaagtaaag
     5521 gttgaacact tcggccgcct gggtggtatc gtgttcactc cggatgaagt actgaacgcg
     5581 cttaaggaat tgataattga gaattgaaaa ttaagaatta tcgatgacac gcggaagtaa
     5641 aacagacagc atattgacaa tcctgttcat ggtattggcg gcagcagcga ttatctgcta
     5701 ctttgccgtc gacgaccgtc acgtatttct ctattgcggc ggagcagcca tatgcttcag
     5761 acttgttcaa tatctactga gatttattag ttaatttagt aacaattatg gaactcaacg
     5821 aaataattaa accggagaat ctggtctata caaaaccgga attgatgaac gacaatccca
     5881 tgcactactg tcccggttgc agccacggtg tgatacataa gctgatcgcc gaagtgatcg
     5941 ccgaaatggg aatggaagaa aaaacaatag gtgtctcccc ggtgggttgc gccgttttcg
     6001 catataacta tcnnnnnnnn nnnnnnnnta tagactggga agaagcagct cacggacgtg
     6061 ctccggcgat tgctactgcc atcaaacgtc tgaatccgga aaagatggtc ttcacctatc
     6121 agggtgacgg cgacctggcc gctatcggta cagccgaaac catccatgct gccaaccgcg
     6181 gtgagaacat tgtgatcgta ttcgtgaaca atgccatcta tggtatgacc ggcggacaga
     6241 tggctcctac cacactggaa ggtatgccga cagccacttg cccatacggc cgtaacatcg
     6301 ccctgaacgg ttacccattg aagatcggtg atctgctggc tcagctggaa ggaacctgtc
     6361 tggttacccg ccaaagcgta cagacagccg ccgccgttcg taaagccaag aagatgcttc
     6421 gcaaagcctt cgaaaactct atggcaggca aaggcacgtc agttgtcgaa ttcgtttcca
     6481 cctgttcatc cggttggaag atgacacctg aaaaagcaaa caaatggatg gaggaaaaca
     6541 tgttcccgtt ctatccgctg ggtgatctaa aaaataaaga ataagtaaat acaaaaacga
     6601 catgaaacaa gaaataatta tagcaggctt tggtggacaa ggtgttctgt cgatgggtaa
     6661 gatacttgct tattccggac tgatggaagg caaagaggtt agctggatgc cttcatacgg
     6721 gcctgaacag cgtggcggta cggctaacgt gaccgttatc ctgagcgacg acccgatcag
     6781 ttctccgatc ctgaacgaat acgatatcgc gatcatcctg aaccagcctt ccatggacaa
     6841 gttcgaaagc aaagtaaaac cgggtggtat cctgatctat gacggatatg gaatccatac
     6901 tccggtgaaa cgtacggata tcagcgttta tcgtgtggat gctatggacg cagctaccga
     6961 aatgaagaat gaaaaagcat tcaatatgct tatcctgggt ggtctgctga agatcgttcc
     7021 gatggtgaaa cttgaaaacg tattgctggg tctgaagaag tccctgcccg aacgtcacca
     7081 caagttaatc ccgatgaacg aagccgccat caagaagggg atggaaatta tacagaaaat
     7141 gtaatcttgc aaaaagaata taaagaaggg cgtttctttc gtagaaatgc ccttttgttt
     7201 tatctttgca acccatgaag cattgcttat acatattatt attgctgata gtatctgcca
     7261 caaccgttca ggcccaacgt ggagccagca gggcagatca gaaaggtgga ggaaaacgtg
     7321 gcggcttctc cttgtcaaac ctgacttctt ctcagaaaga tataccggac agtctgctgg
     7381 tagcggatag tgccgcctta aattcaaagc gtataaccgc ctatcggctt accccttccc
     7441 tgggtgaggc atatgtggcg ccactggata cgaacaagct gaatttcagc aactcgacac
     7501 tggtggaaag taaatcgctc gccatcggtt acctggctaa cctgggagca ccggcacaga
     7561 cgaaaatatt ctccgaacgg caggaagcac gcgattttat cttcgccgat gcctacgatt
     7621 actatatcac aacgccggaa aacgcttatt tctacaacac aaagattcct tataccaacg
     7681 ttctgtacac caccgccggc ggtagtacaa acaaagaaga acagttgaaa ggaaccatga
     7741 ccatgaattt cggtaaaaag atcaatgtgg gtgccgatat cgactatatt tatggccgcg
     7801 gacattataa aaacaacggt aataaactgt taagctaccg tttcttcggc agctaccaga
     7861 ccgaccggta cgaaatgcat gcctacctga gcaacttcaa cttcgtaaac tacgaaaacg
     7921 gaggaatggc aaacgactca accatcagtc atcccgacga gtatttcccg gaaggacgtc
     7981 cctccgatac aaaatcgtac gacatacgtt atctgaccaa tgcctggaac cgtgttcgcg
     8041 ggaaacggta tttcctgacc cagcgttata acctcggttt cacacgtgag ttggaggaag
     8101 aggatgaaga agggaatccc aaagaaatgt tcgtcccggt atccagcatt atccatacga
     8161 tcgattatga agataaccgt cgccggttca tcgccgacaa tacggcgctg atggattcgt
     8221 cctatatagt cgacgacaac ggcctgcgtt tcccacgtat ttatggacta ggagctacac
     8281 tcaacgacca gacatcttca tggaatctga aaaatacgat cggactttcc ctgcgtgaag
     8341 gtttccagga ctgggttaag tttggtttga cagctttcgt cagactcgaa aaacgccggt
     8401 tcaaactgga acccagaata gaagggctcg attatggcga atatggccgg ggtccatact
     8461 tctctgttga taatatcgac ctgaagaacc tgcctacggc aaagctttac gacgagtttt
     8521 ctacttacgt tggagccgaa ctttccaaac gccagggtag catcctgacc tataatgcac
     8581 gcggagaact ttgtatggta ggtagcgacg tcggtgagtt ccgtgttacc ggggatttgc
     8641 aaacccgttt caagttgttc aataaagatg ctgtgatcaa agcagacgcc tatataaaga
     8701 atgtaacgcc ggccttttac atgcgccata accattcccg ttattactgg tgggataacc
     8761 ccaactttaa catgacgcag caaatctatg cgggcggtga agtgtatctg gaatcttcaa
     8821 agactacttt gaaagccgga gtggaaagta ttcagaatta tatctatttc aataaacagg
     8881 gattcccggt acagcatggc agcaacttac aggtagtcag tgcacgcatc aaacaagact
     8941 tccgcttccg tgctttcggc tgggaaaatg aagcatgctg gcagttaagc agcgatgaaa
     9001 gcgtactccc gcttccgtca ttaagtgcct attcaaatat gtatctggcc atcaaggtgg
     9061 cgaaagtact gaccgtacag ctaggtgcca atgtatatta taatacagct tattatgcac
     9121 cttactacga accggcaaca cagcagttcc aggttcagga tgaagtaaaa gtcggtaatt
     9181 atccactggt taacgcctac gtaaacttcc acctgaaaca ggcccggttc tttgtgatgg
     9241 cttacaacct gagcagtaag tttgctgatc cgaactattt ctccctggca cactatccgt
     9301 tgaatccgat ggtgttgaaa atgggtattg ccgttacatt caataactaa gccgtatgaa
     9361 atcccggaag ttactggtag tctatattgt cctcctggca tgcgtactga tagccatgtt
     9421 ccgtttatgg ccgtacaagc aggaacctgt cccacccagg gattatccgg aaattaagtc
     9481 agaaggtatt ctgcgactgg ttaccgaata taaccagtcc ggctattatg tagccggcga
     9541 tacgatcgaa ggtttccaat acgaactgag ccaggccatc tccgctttat ccggactgga
     9601 agtacagact cagctggaga tgagcctggc cgaaagtttc aaacaattat ccaataacca
     9661 atgcgacgta atcgcccgca atattcctat caccagcgac atcaaagagg actatctgtt
     9721 caccgatccg atcgtcttca ataaacaagt actggtgcaa cgcacggaag aagccaataa
     9781 cggcatcaaa ccgatccgta atcaactcga cctggcacaa aagaccttgt atattccgaa
     9841 aaactccccc gccttactgc gcctgcaaaa tctggcacac gaaataggag atacaatcta
     9901 tgtgatagaa gatgaacttt attccagcga acagctggct attatggttg ccaaaggcga
     9961 catcgactat gccgtatgcg accagcaaat agcccgcgta tctaaaggaa atttaccgga
    10021 aatagatatc gacacggata tcagtttcac ccaactccag tcgtgggcag tacgcaaaga
    10081 ctcccctatc ctgctcgaca gcctgaacag ctggctgtca caaatcaaag aaagcgggtt
    10141 atacgatcag atttacaaac gctactataa ataaaagtat atcctcattc ttctcgtgaa
    10201 ggcaggataa acgaaaaagt ggaaccttcc cctagttgcg attctacacg gatcgagcct
    10261 cccattttag taacgagtcc tttgcatata gcaagtccca ggccgatacc ttccacatag
    10321 tcattgactt taacaaagcg gttaaagagg ttttgtagct gctcctcggc tatcccctgt
    10381 ccggtatcct tcacatagaa attcagccgg ccatcttcca gcgccttata ccccatcgta
    10441 atactaccct ttttagtatt cttgatcgca ttattgacca ggttattcac taattggagt
    10501 aagcggatat aatcggttcc aaaggtacag ctgtccaatc ctttttccag aatcaacttc
    10561 acatctttcg gcatacgggg ctttacggaa gcataggtcg tatccatcat ctcgttcagg
    10621 tcgatcggag cataactaat ctttatcgca tccgcctcaa tcttcgacaa gtccagaata
    10681 tcgttgataa gctgcataag caattgatta ttcgccttga tgatctcgta ataagacata
    10741 cgctcctcgt ccgtatccgc aaacgccatc atttctgaaa aaccggttat tgcattcaac
    10801 ggcgtacgga tctcatgact catgtctgcc agatattttg atttcaactt atcagccatt
    10861 tccgccttat cacgctcatc ttcgagacgt ttttctattg cccgcttaac agtggcatca
    10921 cgccacaaag ccaacaacaa aggttttcca ttgcttaaag aaatcggata cttttctact
    10981 tcaagatatt tcatcgcgcc ggaagcatcc ttgagccagc cgtgaaattc ggccaccttt
    11041 cccgaactga tgaccttctt atctacctcc agtcgttcct ctaccgacat caaggcatta
    11101 taatacactt cagagtcatc atgtccctcg atctgggaag tatcgatccc cgttatctct
    11161 tccataaatt tattccagta aagataattg aaatgatctt ccggatcttt tacaaataca
    11221 cccagtggca aatgatctaa tatcgtattc agtaactcat gaacagtatc cggctcattt
    11281 aaggttactt tcttttgaga gctgttacag ctatcatctg ttcccataat ataactcgct
    11341 atttttccaa tgtgggcaaa gatattaatt ttttatgtta ccccactata tagatatatc
    11401 aattttcaac gcttacagaa atttacagga caattgttac aagagccggt gttactattg
    11461 tagaatttga caaatattat ttacctttac ggagaattta atgatagaag atgagatttg
    11521 acgaattgga tttagaagag gccgtattgg acggactcga tgctatgaat tttcaggata
    11581 caactcctgt acaggaatta acgattcctg ttattttaga agggaaggat attattgcct
    11641 gcgcacaaac cggtacaggg aaaacagcag cctacgtgct gccattaatt aatcaattaa
    11701 gtaaaggcaa tcatcctgac aatgcggtca atgcagttat catggctcca acccgcgagt
    11761 tggcccagca gatagaccag cagatcgaag gttttacata ttttgttccg gtatcggctg
    11821 tggccgtata cggtggtacc gacggagttg cctgggagca acagaagcgt ggtatggaaa
    11881 tgggggccga tattgttatc gccactccgg gacgtttgtt gtcccacctg aaactgggaa
    11941 cggtagacct ttcacaggtt tcctattttg tactggatga agcagaccgt atgctggata
    12001 tgggatttta cgacgacatc atgcaggtat acaaacaact gcctcctact tgtcagacta
    12061 tcatgttctc ggctaccatg cctcccaaaa tccggacgtt agcaaaaaca atcctgaaga
    12121 atcccgaaga agtcaaaata gccatctcac gtcctcccga aacaattatg cagacggcct
    12181 atatctgcta tgatcctcag aagctaaaga tactcgaaga cctgttcctg caaagccgcc
    12241 cgcagcgtgt cattattttc tcttcctcca aaatgaaagt gaaagaactt gcctccaccc
    12301 tgaaacggat gaagttcaat gtagctgcca tgcactccga cctggagcag tcgcagcgcg
    12361 aggaagtaat gaaagaattc aagaacggac atatcgatat actggtggca accgatgttg
    12421 tttcgcgcgg tatcgacatc aacgacatca aactggtgat taactacgat atcccccacg
    12481 acccggaaga ttacgtacac cgcatcggcc gtaccgcccg tggtaccgga ggcgaaggat
    12541 tagccatcac attcatcagc attgaagagc aggcacaatt caaacgtatt gaagacttcc
    12601 tggaaaaaga agtttataag attcctatcg acccgaagtt cggcgaaacc ccgctatacg
    12661 aacctgaaaa gtacggaaac atgcgccgcg gacgcggacg tccccggaaa gatggtaata
    12721 acggaggaag aaaccccgga aacaaacgtc cgggaggcaa ccccaaaagc ggcaaccgcc
    12781 gcggaaggcc ccggaaagaa tcttaataat ctatcgaaat acaatacaga caaatagaat
    12841 agcctcatag agacttctga aaatagcccc gagccatgct tggggttttt atttatccgc
    12901 atattcccct tcagcataaa aaacccggag tcaagaaaac tccgggctaa ttaaaaaatc
    12961 ctatgggact ttcgatatat tttctttgat tccgaatgaa ttatccgttc atggaagcca
    13021 ggaactccat attgtcataa gtctgttcca tacgtttctt tacaaactcc atcgcttcga
    13081 tcgagttcat atccgacaga tatttacgaa ggatccacat acggttcaat gtactttcat
    13141 cctgcaacag gtcgtcgcga cgagtacttg aagcagtaat gtcgacagcc ggataaatac
    13201 gtttgttgga cagcttgcga tccaactgca attccatatt acctgtaccc ttgaactctt
    13261 caaagatcac atcgtccatc ttagaaccag tctcggtcaa tgctgttgcc agaatcgtca
    13321 ggctaccgcc gttttcgata ttacgggctg caccaaagaa acgtttcggc ttctgtaatg
    13381 cgttcgcatc cacaccaccg gaaagaacct taccggaagc cggctgaact gtgttataag
    13441 cacgtgccag acgagtaatg gaatctaaca ggatcactac atcgtgaccg cattcaacca
    13501 tacgttttgc cttgttcaaa acgatttcgg caatctttac gtggcgttct gccggttcgt
    13561 cgaaagtaga agcgatcact tccgcatcga cgctacgagc catatcggtt acttcctccg
    13621 gacgttcgtc aatcaacagg atgatcatat atacttccgg atggtttgct gcaatcgcat
    13681 tggcgatatc tttcagcaac atggttttac cggtcttagg ctgtgctacg atcagaccac
    13741 gctgtccttt accgatcggc gagaacaggt cgactacgcg aacggcgata ttgtcgtata
    13801 ctttcggagc cttgcgtgct gtaagcatga atttttcatc cgggaaaagc ggtgtcagat
    13861 gatcgaaagg aacgcggtcg cgcacttctt ccggcgaacg gccgttgatc ttgtccactt
    13921 ttaccagcgg gaaatatttt tcaccttcct tcggcggacg gatagcacct tccaccacgt
    13981 caccagtctt cagtccgaac agtttgatct gcgactgcga tacataaata tcgtccggtg
    14041 aagtcagata gttataatcg gaagaacgca gaaaaccata accatcctgc atcatttcca
    14101 atacgcctgt accgatcagg ataccgtcaa actcgtattg cttttcctgc gatgcattat
    14161 tattgttatt gttgcgctga ttattgtggt tgttattctg gttgttctgt ctgttgttgt
    14221 tattctgacg gggcgtgttc tgttgctgcg gttgcggagc ggcctgcggt tcaggctgct
    14281 gcggtgcagc tttttcctgt ttggcaggtg aaggagagaa cgggaagagt tggtcgagaa
    14341 ccgacttggt gtccgggtgt ctgaatacaa cccttttagg ttcgttcgct gccggagcct
    14401 ctgctgccg
//
