LOCUS       c00132_gnlPro..        12562 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JADJOCNO_132.
ACCESSION   c00132_gnlPro..
VERSION     c00132_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 12:54:34
            Original ID  :: gnl|Prokka|JADJOCNO_132
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12562
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12562
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3542:7027]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3543..7027
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..12562
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12562
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             80..1903
                     /locus_tag="ctg132_1"
                     /transl_table=11
                     /translation="MNKTILLVVFCFSLFVSGYSQGIRFDSYPSHPRLLVKKGEEQKIK
                     SDLALNPEMLRLHNYLLGQCDDLITTPVLAYKKEGKRLLAVSREALRRIFYLSYAYRMT
                     GEDKYRLRAEQEMIAVCSFTDWNPSHFLDTGEMTMAVAIGYDWLFDRLSPDARRLVQEA
                     ILNKGFAPSRDKRYNWFLRATNNWNQVCNAGLVYGALAVLEDHPEEAREIIERALSTVG
                     LTLKGYGPDGAYPEGYNYWGYGTTFQVLLNAALESALGTDGGLSSAEGFLASARFMQFM
                     TGTTGKCFNFSDSRESVFALPAMYWFADKLQDPTLLWNEKDMLSRAELSFSDEESRFLP
                     LIPIYGSQYKMNELVPPAMKLWAANGQTPVVLVRTGWENGEGFYLGIKGGTASTSHAHM
                     DAGSFVFDASGVRWVQDLGMQEYYSLEKENVDLWNMSQNGQRWNVFRYNNLAHNTLTVN
                     GKYHDVNGFVPVTNIYSEAHKLGASLNMTDLFGGELENAVREVALINEKYLSVIDRVKA
                     GSQPATVRWTIVTGAIPRVLDSHMVELTKDGKCMQLIVDSPSVTSVSVLDNVSKNSYDA
                     SNEGTCRIVFDVSLESGQESDIKVRLVPAAD"
     CDS             complement(1907..3304)
                     /locus_tag="ctg132_2"
                     /transl_table=11
                     /translation="MLQRKMLSFLFMMIFIPSVRAQWKDSTRFINKEHEFETTYNKISE
                     NKVYQMLRVPVPLFAISAITYGQGDKFRTLRNTHTPNFHYRYDDFLQYTPLLAVYGMKL
                     GGVESRSSWPRMIVSNAFSATIMAATVNSMKYTIKRERPDGSKNNSFPSGHTATAFMAA
                     TIMHREYGLTRSPLYSIGGYTVATATAFSRQLNNRHWLSDVLAGAGIGILSTELGYFLA
                     DLIFKDKGLNLPDKLRESAPKGGRPSFLEFAVGYSIINGSIEVGKNIRLSSPGATNVSV
                     KGGYFFNPYFGIGGEITALASPMAFDMSLYTGTTPSTKYDITRIHADPTGVFTFTAGPY
                     FSLPVASKLLLGTKFQAGYSYLVKNEVEMDLQEKHPPYGTINNIAFMKGNGSSNYVLRT
                     GISATGIVSRNLGIRMFVDYDYTFLKAPYEILTSLRDSQPVYGESHLSKHKIHYFTIGA
                     TVTALFW"
     CDS             3543..4268
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg132_3"
                     /sec_met_domain="SucD_FumR (E-value: 2.1e-76, bitscore:
                     245.5, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSVSGLFLVLFLLFHLSMNVAAAFSGEAYNMI
                     CSLLGANWYAVAATLVLAAGVVIHFVYAVLLTLQNRKARGNDRYAINARPKGVEWASQN
                     MLVLGIIIILFMVLHFSQFWYKMMFAELLGNHMVTLCDGTTTVSPQDGAAFINYYFQGN
                     ILNTVLYLVWYVALWFHLTHGFWSAIQTIGWSNTIWMNRWICISKIVATVICVVFAIIT
                     IVFYLNGVGGDYVAVCAGH"
     CDS             4302..4688
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg132_4"
                     /sec_met_domain="FAD_binding_2 (E-value: 4.6e-13, bitscore:
                     38.6, seeds: 62, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQIDSKIPQGPLAEKWKNYKDHQKLVNPANKRRLDVIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVXXXXXXXXXX
                     XXXXPAKQTFIVWLKFPTLLSTSA"
     CDS             4856..6244
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 107.9; E-value:
                     2.1e-33)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg132_5"
                     /sec_met_domain="FAD_binding_2 (E-value: 4e-34, bitscore:
                     107.9, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 4.9e-39,
                     bitscore: 123.0, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYTRHEMLDVVKVDGRARGIIARNLITGQIERFSAHAVVVATGGY
                     VNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDYQSKLTLMSESLR
                     NDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDVASRAAKER
                     CDAGFGVNNTGLAVFLDFSDAINRLGKDVVKAKYGNLFDMYEEITNDDPYETPMMIYPA
                     LHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYFVLPYTIQN
                     YLSDQIQVPRFSTDLPEFAEAEKGIKDRIKKLMSIKGKESVDSIHKKLGHIMWEHVGMA
                     RDAKGLQEAIQMLKELKKEFWSNVYIPGEADNLNVELDKALRLADFIEIGTLMAHDALD
                     RAESCGGHFRTEHQTEEGEALRHDDKFMYVSCWEYQGEDKDPVMLKEDLNYQFVVPQTR
                     NYKK"
     CDS             6272..7027
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg132_6"
                     /sec_met_domain="Fer2_3 (E-value: 8.1e-27, bitscore: 83.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 2.7e-12, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.9e-06, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDIKVTLKVWRQKSPKDKGQFETYQIDKINQSVSFLEMLDILN
                     ERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANSIAIPRADAEMAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFICAKLQD"
     CDS             complement(7326..8171)
                     /locus_tag="ctg132_7"
                     /transl_table=11
                     /translation="MEDNIPKFDLPVDFIVGNSITGEILNQYGRFPCKIKAGIFVLCVQ
                     GTVHATVNLTEFTIRKNDFITLPPGCFIQIHEVSDDVKLCFAGFSSVFVSHINYIKTIT
                     NYLPVIFDSPIMPLPEHISLLYQQAFDLLINAYSMPKTIENKEIIKAIFTIFMQGVIEL
                     YRNHTPYSNAPMTRNMEICREFVQLAMENYTKEHSVSYYAKRLNITLQHFCYVIKKVSG
                     RTALDILSNIIIMDAKAQLKSTDMPVKKIAFALGFDNLSFFNKYFRQHVGMTPQEYRES
                     "
     CDS             8412..9626
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg132_8"
                     /sec_met_domain="Radical_SAM (E-value: 1.7e-14, bitscore:
                     44.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTKRTKSSFRTMSTNRKLESVFLFVTGRCNAKCKMCFYAEDMDK
                     KEKDLTFEEIKTISETAGQFNRLWVSGGEPTLREELPEIIEMFYKNNEIKDVNIPTNGL
                     KPDRIVAWVKQIRQNCPELNINLSLSLDGFGDTHDIQRGVPGNFYKAMGTLKLIEKNFA
                     DDGRVLKNLATVITKYNENEVEDLMIWMLGRFHLSNHIIEAARGMTRDDGVKVLTEPTL
                     RALQDKVVPIYNVYGERMAEETGGFRKPIARFFYLGFIRTLYNVRATNIDHPTPWGMDC
                     TAGETTLVIDYDGRFRACELREPLGNVKDYDCNIAKIMESDAMKQEIAAIGHGDKANCW
                     CTHGCWITSSLVFNPRKMITQVYKGYREMKKLNRPLNISEELLQSIERKYALDEQKLVE
                     LGVRN"
     CDS             9804..10388
                     /locus_tag="ctg132_9"
                     /transl_table=11
                     /translation="MTTKLKDLFDTFLNIAASSQKLGINLIRVAILIIFVWIGGLKFYN
                     YEAEGIVPFVANSPFMSFFYAKSAPEYKEYKLKEGEFNEAKHQWHVENNTYIFSHGLGI
                     MIMAIGILTFLGIFSPKIGLIGSGLAIIMTLGTLSFLVTTPEVWVPDLGSGEHGFPLLT
                     GAGRLVIKDTAIIAGAIVVLSDCAQRILKKK"
     CDS             10794..11543
                     /locus_tag="ctg132_10"
                     /transl_table=11
                     /translation="MNLRKNLFWAIPFIVVGVVWIMRNTGMITDDLFHIIVSWQMLVMY
                     IGIGSISRRHYIGGLITFLVGAAFLLPRLGWMDSDWLQVYWPAAFVIVGLMLIFEPRKK
                     NSYHYNSRREDTGGEDIRGNAVAGKVKSDFINTDGYVESDNTFGYVEQIILDPVFKGAR
                     IRTVFGGTVLDLRKTKLDSAKTYIDIDCKFAGVEIYLPGDWAVNFHGSPIMGACEDKRF
                     NASMEMDKEHILVVRGIVMFGGIEFKS"
     CDS             11546..12352
                     /locus_tag="ctg132_11"
                     /transl_table=11
                     /translation="MQTHPFINSVLCRMAGVALAVVSCSISALLLYYYGHTGWLVAWLD
                     SLVSVGIFCVSGFLFWYVTGILRPLQAQIALAVGVLIISVTGGYMAGALVYPDRMDWFA
                     STIPFRILLGLLGWIILAQWYYIRWKELQMEIQEEQRKEENAPAETGVSSPEEEAILDR
                     ISVKDGSRIHLIHLEELLYIQASGDYVALFTTDGQYIKDQTMKYFESHLPANLFIRIHR
                     SCIVNSEQIMRVELFGKESYQVRLKTGVCLRASLTGYKLLKERLSL"
     CDS             complement(12330..12521)
                     /locus_tag="ctg132_12"
                     /transl_table=11
                     /translation="MKKPQYKDKPETSVCQVFYRQYMLSLSGIVAKNCFRTQNFIQYRQ
                     KLLILTVKTAKSIEKDVL"
ORIGIN
        1 ggtctttatt tttattagac gcgcttataa atctcaattt ttatgtaagt ttgtaactcc
       61 aattaaatat aatacctgta tgaataaaac tatcctgctt gttgtgtttt gcttttccct
      121 gttcgtttcg gggtattcac agggaatacg ctttgattct tacccttctc atccccggtt
      181 gctggtaaag aaaggagagg agcaaaagat taaatccgat ctggctctta atccggagat
      241 gctccggttg cataactatc tacttgggca atgcgacgat ctgatcacga cgcctgtgct
      301 ggcatataaa aaagaaggga aacggttgct ggccgtatcg cgtgaagcct tgcggcgtat
      361 cttctatctt tcatatgctt accggatgac aggagaggat aagtatcgtt tgcgggcaga
      421 gcaggaaatg attgccgtgt gttcgtttac cgattggaac ccgtcccatt ttctggatac
      481 gggcgaaatg actatggcgg ttgcaatcgg ttatgactgg ttgttcgatc ggttatctcc
      541 ggatgcccgg aggctggtgc aggaggcgat tctgaataaa ggttttgccc cgtcgaggga
      601 taaaagatat aactggtttc tgagagcgac caataactgg aaccaggtct gtaatgccgg
      661 actggtttac ggtgcacttg ccgttttaga agatcatccg gaagaggccc gtgaaatcat
      721 tgaacgtgct ttatctacag tcggcttgac tttgaagggc tatggtcccg atggcgctta
      781 tcccgaagga tataattatt ggggatacgg gactaccttc caggttcttt tgaatgccgc
      841 gttggaatcc gccttgggga ctgacggcgg tctctcttcg gctgaaggtt ttctggcttc
      901 tgcccgtttt atgcagttta tgaccggaac gaccggtaaa tgctttaact tcagcgattc
      961 ccgtgagagt gtctttgctt tgccggctat gtactggttt gccgacaagc tgcaagaccc
     1021 tacactgctt tggaatgaaa aggatatgtt gagtcgggcg gagttgtctt tttcggatga
     1081 ggagagccgt ttccttccgt tgattccgat ttatggttca caatataaaa tgaatgaact
     1141 ggtgcctcct gctatgaaat tgtgggcggc taacggacag acgcctgtcg tgctggtccg
     1201 tacgggttgg gagaatggag aaggtttcta tctgggaata aaaggaggaa cggcttcgac
     1261 cagccatgcc catatggatg ccggatcgtt tgtgttcgat gcttcgggtg ttcgctgggt
     1321 gcaggacctg gggatgcagg aatattattc gctggaaaag gaaaatgtag atttatggaa
     1381 tatgtcgcag aacgggcagc gctggaatgt gttccgttat aataacctgg cgcataatac
     1441 actgactgta aacggtaaat accatgatgt aaacggtttt gtacctgtga caaatatcta
     1501 ttcggaagcg cataaactcg gagcttctct gaatatgacg gacttgttcg gcggagaatt
     1561 ggaaaatgcc gtccgtgaag ttgctctgat caatgaaaaa tatctgtcgg tgattgatcg
     1621 tgtaaaagct ggcagtcagc cggcaactgt cagatggacg attgtaaccg gggccattcc
     1681 ccgtgtattg gacagtcata tggtggaact gacaaaagac ggcaaatgta tgcaactgat
     1741 cgttgatagt ccatccgtaa cttctgtgtc cgtccttgat aatgtatcga agaatagcta
     1801 tgatgcttcc aatgagggaa cctgccgtat cgttttcgat gtaagtctgg aaagcgggca
     1861 ggagagcgat atcaaagtcc ggctggttcc tgctgctgac tgataattac cagaacagcg
     1921 ccgttacggt tgcccctatt gtaaaatagt gtattttgtg cttgcttaaa tggctctcgc
     1981 cgtagactgg ttggctgtct ctgaggctgg ttaagatttc gtaaggtgct ttcaggaacg
     2041 tataatcgta atctacgaac atacggatac ccaggttgcg gctgacgatc ccggtcgctg
     2101 aaatgcctgt gcgtaaaaca tagttgctgc taccgttgcc tttcataaaa gcaatattat
     2161 ttatggttcc gtatgggggg tgcttttcct gtaagtccat ttccacttca tttttcacca
     2221 gataggaata tccggcctgg aactttgttc ctaaaagcaa tttactggct acaggtaacg
     2281 agaaataagg ccctgccgta aaagtaaaaa caccggtcgg atcggcatgg atgcgggtga
     2341 tgtcatattt ggttgaaggg gttgttcctg tataaagcga catgtcgaat gccatcgggc
     2401 ttgccagcgc tgttatttcg ccgccgatac cgaaataagg attgaagaag taaccgcctt
     2461 ttacgctgac attggttgct cccggcgagc tcaggcgtat atttttacct acctcgatac
     2521 ttccgttgat gatactgtat cctacggcga actccaggaa agaagggcgc cctcctttgg
     2581 gggcagactc cctgagcttg tcagggagat tcaagccttt gtccttgaag atcaggtctg
     2641 ccagaaaata ccctaactct gtggataaga tgccgatacc ggccccggcc agtacgtcgc
     2701 tcagccagtg gcggttgttc agttgccggc tgaaagcggt ggctgtggcg actgtatatc
     2761 ccccgatact atataacggg ctgcgggtca gaccatattc ccggtgcatg atggtagcag
     2821 ccatgaaagc ggttgccgtg tgtcccgaag ggaatgagtt gttctttgag ccgtcggggc
     2881 gttcgcgttt gatcgtatat ttcatgctgt tgacggtagc ggccatgatc gttgccgaaa
     2941 aagcgttcga tacgatcatc cggggccatg aactacgact ttccacaccg ccgagcttca
     3001 tcccgtaaac agcaagcaac ggagtatatt gcagaaaatc atcgtatctg taatggaagt
     3061 tgggcgtatg cgtattgcgc aatgtccgga atttatcgcc ctgcccatat gttatggctg
     3121 aaatggcgaa aagaggaaca gggacacgca gcatctggta taccttattc tctgatattt
     3181 tgttgtaagt ggtttcaaat tcatgttctt tatttatgaa tctcgtacta tctttccact
     3241 gagcacgaac agacggtata aaaatcatca taaataagaa gctcagcatt ttacgttgta
     3301 acatacgatc ccctgattat gccacgaaga tataaaaatg ccggttagta ctggttacat
     3361 tttcgttaat ttatttattg aataggattt accgtttgtc cctcctgaaa tgtataggtt
     3421 tgattggcga aatatttctt taatcgtttg cgtgatacgt gtatttagca tacctttgcc
     3481 tgataattga gtatattgat atgaatttct aaaaacaatt aaataactta aattattatc
     3541 ttatgtggtt acttaattct tctatcggga agaagctgat aatgagtgta tcaggccttt
     3601 ttcttgtttt gttcttattg ttccacttgt caatgaatgt ggcggctgct ttctcgggag
     3661 aagcctataa catgatttgt tcattgttgg gagcaaattg gtatgccgtg gcagcaacat
     3721 tggtgctggc agcaggcgtt gtgattcact ttgtgtatgc tgttctcctt acactgcaaa
     3781 accgtaaggc tcgcggtaac gaccgttatg caattaacgc tcgtccgaaa ggtgtggaat
     3841 gggcatctca gaacatgctg gtactgggta ttatcattat cctgttcatg gtgttgcact
     3901 tcagccagtt ctggtataag atgatgttcg ccgaactcct aggcaatcac atggtaacac
     3961 tttgcgacgg aacaacaacc gtatctcctc aggacggtgc agcgtttatc aactactatt
     4021 tccagggtaa tatcctgaat acagtgctgt atctggtatg gtacgtagct ttgtggttcc
     4081 acctgactca cgggttctgg agcgctattc agactatcgg ttggagtaac acgatctgga
     4141 tgaaccgttg gatctgcatt tccaagattg tagcaaccgt tatttgcgta gtgtttgcta
     4201 tcattactat cgttttctac ctgaatggtg taggtggtga ctatgtagct gtttgtgcag
     4261 gacattaatt taaggtgtaa caatattgaa aataaatcat tatgactcaa atagattcta
     4321 aaatccctca gggcccgttg gctgagaagt ggaaaaatta taaagatcat cagaaactgg
     4381 tgaaccccgc aaacaaacgt cgtctggacg tgattgtagt tggtactggt ctggccggtg
     4441 cttctgctgc tgcctctctg gcagaaatgg gattcaacgt attgaacttc tgtatccagg
     4501 attctccccg tcgcgcacac tcaatcgccg cacagggtgg tatcaatgct gcaaagaatt
     4561 atcagaatga tggtgactct gtnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     4621 nnntgcccgc gaagcaaacg tttatcgtct ggctgaagtt tccaactcta ttatcgacca
     4681 gtgcgtagca cagggtgttc ctttcgctcg cgaatacggt ggtctgctgg ataaccgttc
     4741 attcggtggt gctcaggtat cccgtacgtt ctatgcccgc ggtcagaccg gacagcagtt
     4801 gttgctgggt gcttactctg ctttgagccg tatgatcggt ttgaacaaag taaagatgta
     4861 tacccgccac gaaatgctgg acgttgtgaa ggtggatggc cgtgcccgcg gtatcatcgc
     4921 acgtaacctg atcacaggtc agatcgaacg tttttctgct cacgcagtag tggtggcaac
     4981 aggtggttat gtaaatactt tcttcctgtc tactaacgca atggcttcca acggttctgc
     5041 tgcatggcag tgctacaaga aaggtgctta cttcgctaac ccttgtatgg tgcagatcca
     5101 cccgacttgt gtaccggtga aaggtgacta ccagtctaag ctgactttga tgtctgaatc
     5161 attgcgtaac gacggtcgta tctgggttcc gaagaaactg gaagatgcaa aagcattaca
     5221 ggccggaact aagaaaggga aagacattcc tgaagcagac cgcgactact atctggaacg
     5281 ccgttatccg gcattcggta acctggttcc gcgtgacgtg gcttcacgtg ccgctaaaga
     5341 acgttgcgac gccggcttcg gtgtgaacaa cacaggtctg gccgtgttcc tcgacttctc
     5401 cgacgccatc aaccgtctgg gtaaagatgt tgtaaaagct aaatatggta acttgttcga
     5461 catgtacgaa gaaattacca acgacgatcc atacgaaact ccgatgatga tttatcctgc
     5521 attgcactac tcgatgggtg gtctgtgggt tgactatgaa ttgatgactt ctattccggg
     5581 tctgttcgct atcggtgaag ctaacttctc tgaccacgga gctaaccgtc tgggtgcttc
     5641 tgcgttgatg cagggattgg ccgatggcta ctttgtattg ccttatacaa ttcagaacta
     5701 tctgtcagac cagatccagg ttccacgttt cagcaccgac ctgcctgagt ttgcagaagc
     5761 tgaaaagggg atcaaagacc gcatcaagaa attgatgagt atcaagggta aagagtcggt
     5821 agattctatc cataagaaac tgggtcatat catgtgggaa catgtaggta tggcacgtga
     5881 tgcaaaaggt ttgcaggaag cgatccagat gttgaaagag ctgaagaaag agttctggag
     5941 taatgtatat attccgggtg aagccgataa cctgaacgta gagttggata aggcattgcg
     6001 tttggctgac tttattgaga ttggtacatt gatggcacac gatgcattgg accgtgccga
     6061 atcttgtgga ggacacttcc gtacagagca ccagaccgag gaaggcgaag ccctgcgtca
     6121 tgacgataag ttcatgtacg tatcttgttg ggaataccag ggtgaagaca aagatccggt
     6181 tatgctgaag gaagatttga actatcagtt cgttgttcct caaacacgta actacaagaa
     6241 gtaataatca tcaatcacaa aaattagaat catggataaa gatataaaag taacacttaa
     6301 agtttggcgt cagaaaagtc cgaaagataa aggacaattt gagacttacc aaatagacaa
     6361 aatcaatcag agtgtttctt tcctggaaat gttagacatt ttgaatgaac gtttggtcag
     6421 tgaaggtaaa gagccgatcg tattcgatca cgactgtcgt gaaggtatct gcggtatgtg
     6481 ttctttgtat gtaaacggac atccgcacgg acctgcaacc ggcgcaacta cttgccagct
     6541 ttatatgcgt cgcttcaatg atggcgaaac tattacaatc gaaccgtggc gttctgccgg
     6601 tttcccggta atccgcgact tgatggtaga ccgttatgct tacgataaaa ttatccaggc
     6661 aggtggtttc gtatcagtga acacaggtgg tgtacctgat gccaattcaa tcgctattcc
     6721 tcgtgcagat gctgaaatgg ctatggatgc tgctgcatgt atcggttgcg gtgcttgtgc
     6781 tgctgcttgt aagaacggtt cggctatgtt gttcgtttct gcaaaggtta gccagttggc
     6841 tctgttgcct cagggtaagg tagaagctgc tcgtcgtgcg aaagcaatgg ttgccaagat
     6901 ggacgaactg ggcttcggta actgtaccaa cacgcgtgct tgcgaaatgg aatgtccgaa
     6961 gaacatctct gtcagcaaca tcgctcgttt gaaccgcgag ttcatttgtg ctaaattgca
     7021 agactaatat acattatata tgtatgtccg gagaggcgtt gcttatggca gcgcctcttc
     7081 ttttttgccc ctattttaac atttctgaag tcatagataa atatcttgaa tgttgttagt
     7141 gtttcttata tgctatacaa cactaattag cattttaact attgacaagt tggagaatac
     7201 ctgtatcttt gtactgtggt tttttcataa tagtattaga tttaaggtta acaaagttgg
     7261 ttagggcttg tcgtgagaca ggctttaatt gtttataggg gtttgcgtcc ggcatatccc
     7321 tttttttagc tctccctgta ttcctgcggg gtcattccta catgttgccg gaaatatttg
     7381 ttgaagaacg aaaggttgtc gaaacccagg gcgaatgcaa ttttcttgac cggcatatcg
     7441 gtcgatttaa gctgcgcttt ggcatccata atgatgatat tgctcaggat atccaatgca
     7501 gtccgtccgc tgaccttttt tatcacataa cagaaatgct gcaaggtgat gttgagcctt
     7561 ttggcgtaat aagacacgct atgctctttc gtgtagtttt ccatcgccag ttgtacgaac
     7621 tcccggcata tttccatgtt acgcgtcatg ggagcattgc tatatggcgt atgattcctg
     7681 tataattcaa taaccccttg catgaagata gtaaagattg ccttgataat ctccttgttc
     7741 tcgatggttt taggcatgga ataagcattg atcagcaagt cgaaagcctg ttggtagagt
     7801 aaggatatat gttccggcag aggcatgatc ggactgtcga atatgacagg cagatagttc
     7861 gtaatcgtct ttatataatt gatatggctg acgaatacgg aagaaaagcc tgcaaaacac
     7921 agttttacat catcggaaac ctcatgtatc tgaatgaagc aacccggggg taaggtgata
     7981 aagtcgttct tccggatggt aaactcagtt aagtttacag tcgcgtggac tgtcccttgt
     8041 acgcaaagca cgaatatgcc agccttgatc ttgcacggga aacgtccgta ctggttcagt
     8101 atttcacctg taatactgtt tcctacaata aaatctacgg ggaggtcgaa tttaggaata
     8161 ttgtcttcca tacttttata tacacttaat tgaatgtaca aagatagttt ttttgagaca
     8221 agttagtcga taatcttaaa tatagaacat cgaatcccac aaatggagat tgttttgtgc
     8281 tgtataatag ttgaaatttg cgaatgtttt caagtcttgc tgatagattt gttgggatgg
     8341 tatatatttg tctatctgct aaataagata tgggagctaa tactaataga gaaatctaat
     8401 cgataataac aatgagtacg aaaagaacaa agagctcttt caggacaatg agcacaaaca
     8461 gaaaattaga atctgttttc ctgtttgtca caggacggtg taatgctaaa tgtaaaatgt
     8521 gtttctatgc agaagacatg gataaaaagg agaaagacct gacttttgaa gaaatcaaga
     8581 caatctccga aacagccggg cagttcaacc gtttgtgggt atccggcggt gaaccgacac
     8641 tgcgtgagga gttacctgaa attatagaga tgttctacaa gaataacgag ataaaggacg
     8701 tgaatatccc taccaacgga ttgaagcctg accggatcgt cgcctgggta aaacagatcc
     8761 gccagaattg tccggaactg aatatcaacc tgagcctttc tttggacggt ttcggtgata
     8821 cgcatgatat acagcgcggc gttcccggca atttctacaa agcgatgggg acactgaagc
     8881 tgattgaaaa aaactttgct gacgacggca gggtgttgaa aaacctggcc accgtaatca
     8941 ccaaatataa cgagaatgag gtcgaggatc tgatgatatg gatgctggga cgtttccatc
     9001 tttccaatca tattattgaa gctgcacgcg gtatgacccg cgacgacgga gtgaaggttc
     9061 ttaccgagcc tactctacgc gccttgcagg ataaggttgt tcctatttat aatgtatatg
     9121 gggagcgtat ggcggaggaa accggtgggt tcagaaaacc tatcgcccgt ttcttctacc
     9181 tgggtttcat acgtacatta tataatgtac gtgcgaccaa tatcgatcat ccgacaccct
     9241 ggggtatgga ttgtacggcc ggcgaaacaa cactggtaat agactatgac ggtcgtttcc
     9301 gtgcctgtga acttcgcgaa ccgctcggta atgtcaagga ttatgactgc aatatcgcaa
     9361 agattatgga gagcgatgcc atgaaacaag agattgccgc tatcggtcat ggtgacaagg
     9421 ctaactgctg gtgtacgcat gggtgttgga tcacttcatc gcttgttttc aatccccgca
     9481 agatgatcac gcaggtctat aaaggatacc gggagatgaa gaagctgaac cgtcctctga
     9541 atatcagtga agagcttttg cagagtatcg aacgcaaata tgccttggac gaacagaaac
     9601 tggtggagct gggagttcgt aattaaaata gttccgataa cggatcattt ataaagccgg
     9661 ttgacgggaa atatacctct gttaaccggc tttattgtgt ttaagggaat aattgtcaaa
     9721 ttatccggta gaattgccat ttcccatagg ggaaaaatgt cggatctttg catcataagt
     9781 taaactgata aacaaagaaa gacatgacta ctaaattaaa agatttattc gacacatttc
     9841 tgaacattgc agcttcttca cagaaactgg gtattaacct gatccgcgta gctatcctga
     9901 ttatattcgt atggatcggc gggctgaaat tctataatta tgaagcggaa gggatcgttc
     9961 cttttgtggc aaacagtccg tttatgagct ttttctatgc aaagagtgca ccggaataca
    10021 aagaatataa gttgaaagaa ggtgaattca atgaagccaa gcatcagtgg catgtagaaa
    10081 acaataccta tattttttca catggactag gcattatgat catggcgatc ggtatcctga
    10141 ctttcctggg tatcttttct ccgaaaattg gcttgatagg ttccggactg gcgatcataa
    10201 tgacattggg tacgctttca ttcctggtga caacacctga agtgtgggtg cccgatttgg
    10261 gaagcggaga acatggtttc cccttactga ccggagcagg tcggctggta ataaaagata
    10321 cggcaatcat agccggagcg atcgtggtat tgtccgactg tgcacaacgt atattaaaga
    10381 agaaatagga ataaaaagtg tttattttaa cactttggaa gcaaaaaaca aacatattga
    10441 accttgttag cttttcttat agtgtatgaa acaccattta gcataaaacc tcttgacagg
    10501 tttggattaa gcagtatatt tgcatcgtgg ttttttcata atagtattag atttaaggtt
    10561 aacaaagttg gttagggctt gtcgtgagac aggctttaat tgtttatagg ggtttgcatt
    10621 cggaaatgca agcctttttt cttttaaata tggcattctc tgaaaaataa ctcccttttt
    10681 tatcggtaat attcggcaat tcaccgatat ttgactgtaa taggacgtat ttctattgcc
    10741 ggaaggctga caggagcata cttttgctct caaacaatta aactgtatat cgtatgaatc
    10801 ttaggaaaaa cttattttgg gccatcccgt ttattgtagt gggggtcgta tggatcatga
    10861 ggaacacagg catgatcacg gatgatcttt ttcatatcat tgtatcctgg cagatgcttg
    10921 taatgtatat aggtataggg agtatttccc ggagacatta tataggcggt ttgattacct
    10981 ttttggttgg tgcggcattt ttactgccac gactggggtg gatggatagc gattggttgc
    11041 aggtctattg gccggctgct tttgtcattg tcggtttaat gctgatcttc gaaccgcgta
    11101 aaaagaactc ctatcattac aatagccgga gagaggatac cggtggagaa gatatccggg
    11161 gaaatgccgt tgccggtaaa gtaaaaagtg attttattaa tacggacgga tatgtggaat
    11221 cggataatac atttggctat gtggaacaaa ttattttaga tccggtattt aaaggagcca
    11281 ggattaggac tgtgtttggg ggaacggtcc tggatttgcg gaaaacgaag ctggatagtg
    11341 ctaaaaccta tattgatatc gattgtaagt ttgccggtgt ggaaatctat cttcctgggg
    11401 attgggcggt caattttcat ggcagtccga tcatgggggc atgcgaggat aaacgtttta
    11461 atgcctctat ggaaatggat aaagaacata tactggttgt acggggaatt gttatgttcg
    11521 gtggcattga atttaagagt tgattatgca gacacatccg tttataaatt ctgtcctgtg
    11581 tagaatggct ggtgtggctt tggctgtggt cagttgcagc ataagcgcct tgctcctcta
    11641 ttattacgga catacgggat ggcttgtcgc atggttggat agtctggttt cggtcggtat
    11701 attctgtgtc tccggtttcc tgttctggta tgtaacaggc atattgcggc cattacaggc
    11761 ccagattgca ttggctgttg gcgtccttat catatccgtt accggaggat atatggccgg
    11821 ggcgctggtt tatccggata ggatggattg gtttgcatct accattccgt tccgtatttt
    11881 gttgggtttg ctgggatgga ttattttggc ccagtggtat tatatccgtt ggaaggagtt
    11941 gcagatggag atacaggagg aacagagaaa agaagaaaat gctccggcgg aaacaggcgt
    12001 atcgtcaccg gaagaggaag caatactgga tcgcatctct gtgaaggatg gcagccgtat
    12061 ccatctgatc cacctggagg agttacttta tatccaggcc agcggtgact atgtggcact
    12121 cttcacgacc gacggacagt atataaaaga tcagacaatg aaatattttg aatcgcatct
    12181 gccggcaaac ctgtttatcc gtattcaccg ttcctgtatc gttaatagcg aacagatcat
    12241 gcgtgtggaa ctgttcggca aggaaagtta ccaggttcgt cttaaaacag gtgtctgtct
    12301 gcgtgccagc ctgaccggat acaagttgct taaagaacgt ctttctctat agatttggct
    12361 gttttaactg ttaaaattag cagtttttgt ctgtattgta taaagttttg tgttcggaaa
    12421 caatttttag ctacaatgcc cgaaaggctt aacatatatt gtctgtaaaa gacttgacaa
    12481 acgcttgttt caggcttatc tttgtactgt ggttttttca taatagtatt agatttaagg
    12541 ttaacaaagt tggttagggc tt
//
