LOCUS       c00071_gnlPro..        14417 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HDJKMIGB_71.
ACCESSION   c00071_gnlPro..
VERSION     c00071_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 13:03:13
            Original ID  :: gnl|Prokka|HDJKMIGB_71
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1391
            Orig. end    :: 15808
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14417
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[11391:15579]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14188
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..14417
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14417
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(848..2071)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Oxidored_FMN"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg71_4"
                     /sec_met_domain="Oxidored_FMN (E-value: 4.4e-51, bitscore:
                     163.9, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESKLFTPVTFGPLTLRNRTIRSAAFESMCPGNAPSDMLLDYHRS
                     VAAGGIGMTTVAYAAVTQSGLSFDRQLWMRPEIIPGLRRLTDAIHAEGAAAGIQLGHCG
                     NMSHKSICGCMPVGASSGFNLYSPTFVRGLRADELPEMARAYGRSVNLAREAGFDSVEI
                     HAGHGYLISQFLSPSTNHRKDEFGGSLQNRMRFMDMVMEEVMKAAGSDMAVLVKMNMRD
                     GFRGGMELDETMQVARRLEQSGAHALVLSGGFVSKAPMYVMRGEMPIRSMTHYMTCWWL
                     KYGVRMVGKWMIPSVPFKEAYFLEDALKFRAALKIPLVYVGGLVSRDKIDEVLDDGFEA
                     VQMARALLNEPGFVNRMRAEENARCNCRHSNYCIARMYSIEMACHQHLKEELPPCLKKE
                     IEKIEAKG"
     CDS             complement(2130..2900)
                     /locus_tag="ctg71_5"
                     /transl_table=11
                     /translation="MNQETFQIFLWVMSAVALVVFIALYFVKAGYGMFRTASWGISINN
                     KLAWVLMEAPVFIVMFGLWGKSGAGFAVPVYFFFLLFQLHYLQRAFIFPFLLKGKSRMP
                     VAIMAMGIVFNLLNGMMQAGGLFYFAPEGLYADGWAYLLKPHALLGIILFFAGMFVNLH
                     SDYVIRHLRRPGDTKHYLPGKGLYRYVTSANYFGELVEWTGFAILTASPAAWVFVWWTF
                     ANLVPRADAIHRRYREEFGDEAVGKRKRIIPFLY"
     CDS             complement(3148..4491)
                     /locus_tag="ctg71_6"
                     /transl_table=11
                     /translation="MKKEYLIYKLSEDLKEATRIENELFRKFDVKRGLRNEDGTGVLVG
                     LTKIGNVVGYERIPGGGLKPIPGKLFYRGYDVDDLAHAIIKEKRFGFEEIAYLLLSGRL
                     PDKEELSSFRELINDNMPLEQKTKMNIIELEGNNIMNILARSVLEMYRFDPDADDTSRD
                     NLMRQSIELISKFPTIIAYAYNMLRHATHGRSLHIRHPQENLSIAENFLYMLKKDYTEL
                     DARTLDLLLVLQAEHGGGNNSTFTVRVTSSTGTDTYSSIAAGIGSLKGPLHGGANIQVA
                     DMFHHLQENIQDWTNVDEIDTYFTRMLNKEVYNKTGLIYGIGHAVYTISDPRAILLKEL
                     ARDLAREKGKEREFAFLELLEERAIDVFGRVKNNGKTVSSNVDFYSGFVYEMIGLPQEI
                     FTPLFAMARIVGWCAHRNEELNFEGKRIIRPAYKNVLDEVTYVPIKKR"
     CDS             complement(4504..5664)
                     /locus_tag="ctg71_7"
                     /transl_table=11
                     /translation="MEKITVPFITGDGVGAEVTPSMQAVVNAAVKKSYGDRRGIEWKEV
                     LAGERAFHETGSWLPDETMEAFRTYKVGIKGPLTTPVGGGIRSLNVALRQTLDLYVCQR
                     PVRWYKGIVSPLKEPQKVDMCVFRENTEDIYAGIEWEAGTPEAEKFYRFLRDDMGVTKV
                     RFPETSSFGVKPVSREGTERLVRAACRYALEHHLPSVTLVHKGNIMKFTEGGFKKWGYE
                     LAEREFGKELAEGRLVIKDCIADAFLQNTLLIPEEYSVIATLNLNGDYVSDQLAAMVGG
                     IGIAPGANINYKTGHAIFEATHGTAPNIAGKDIVNPCSIILSAVMMLEYLGWKEAASLI
                     ENALEESFTEARATADLARFMPGSVSLSTSTFTREIVRRIENGNNE"
     CDS             complement(5668..7911)
                     /locus_tag="ctg71_8"
                     /transl_table=11
                     /translation="MVYDLTMLKTFYAAYSEKIERVRNVLRRPMTLAEKILYAHLYDGD
                     KVKNYRRGEDYVNFRPDRVAMQDATAQMALLQFMNAGREQVAVPSTVHCDHLIQAYKGA
                     KEDVATATKTNEEVYNFLRDVSSRYGIGFWQPGAGIIHQVVLENYAFPGGMMVGTDSHT
                     PNAGGLGMVAIGVGGADAVDVMTGMEWELKKPRLIGVHLKGKLSGWVAPKDVILKLAGI
                     LTVKGGTNAIIEYFGPGTASLSATGKATICNMGAEVGATTSLFPYDERMGTYLKATGRE
                     EVAEMAASVAADLRADDEVLANPEKYYDRIIEIDLSLLEPYINGPFTPDAATPISKFAE
                     VVITNNYPRRMEVGLIGSCTNSSYQDLSRAASLARQVKEKNLKVASSLIVNPGSEQIRA
                     TAERDGMIAAFEDIGATIMANACGPCIGQWKRHTDDPERKNSIVTSFNRNFAKRADGNP
                     NTFAYVASPEITMALTIAGDLCFDPLRDTLVNAKGEVVKLSEPVGEELPAHGFIGGKEG
                     YIAPGKGQTEITVNPHSQRLQLLTPFPAWDGMDLLDMPLLIKVQGKCTTDHISMAGPWL
                     RFRGHLENISDNMLMGAVNAFNGETNKVWNRSTNTYGTVSGTAKLYKSEGIPSMVVAEE
                     NYGEGSSREHAAMEPRFLNVRVILAKSFARIHETNLKKQGMLALTFTDKADYDKIRERD
                     LISVMGLKDFAPGRTLKVVLHHEDGSKESFEVQHTYNEQQIAWFRAGSALNAR"
     CDS             8026..9939
                     /locus_tag="ctg71_9"
                     /transl_table=11
                     /translation="MITFATMKEQDSNSPIIHLQQQQVLLRMEYEYEKEEFKRQTENMG
                     VARKVKRGLCWYPATPGRSYYNSLNQLVIEITHTENTDIEHNFEFGRPVCFFRQSADGK
                     ITYMNFTATVSYADETRMVAIMPGAGAVMEVQETDNLGVQLYFDETSYRTMFEALEDTL
                     RSKGNRLAELRDILLGTSKAGFRELYPVRFPWLNSTQETAVNKVLCARDVAIVHGPPGT
                     GKTTTLVEAIYETLHREPQVLVCAQSNTAVDWISEKLVDRGVNVLRIGNPTRVNDKMLS
                     FTYERRFENHPLYPELWSIRKNLRELGSRARRGSYDEREGVRSRMSRLRDRATALEIQI
                     NAELFDGAHVIASTLVSSNHRLLNGRRFGTLFIDEAAQALEAACWIAIRKADRVVLAGD
                     HCQLPPTIKCYEAARGGLERTLMEKVVSNKPAVVSLLKVQYRMHEEIMKFPSQWFYNGE
                     LEAAPEVRYRGILDWDTPIHWIDTSEMDFKEEFVGETFGRINKAEADLLLSELKIYINR
                     IGGSRILEEKIDFGIISPYKAQVQYLRSKIKADASLKPYRSLFTVNTVDGFQGQERDVI
                     FISLVRANEEGQIGFLNDLRRMNVAITRARMKLVILGEAETLKHHGFYRKLLEFIQNIG
                     NQ"
     CDS             complement(10001..11044)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_10"
                     /sec_met_domain="IlvN (E-value: 5.4e-47, bitscore: 149.3,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 4.8e-41, bitscore: 130.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGVIENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     ACNLRDNGFNVIVGQRPGKTYEKAVADGWVPGETLFGIEEACQKGTIIMCLLSDAAVMS
                     VWPTIKPYLTPGKALYFSHGFAITWNDRTGVVPPKDIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAVYQDATGKAFDKTIALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMT
                     PFHDAIKPVVQKLYASVKSGNEAQISIDSNSKPDYREKLNAELKALRESEMWQTAVTVR
                     KLRPENN"
     CDS             complement(11095..11847)
                     /locus_tag="ctg71_11"
                     /transl_table=11
                     /translation="MMSENNKIGTYKFVAEPFHVDFTGRLTMGVLGNHLLNCAGFHASD
                     RGFGIATLNEDNYTWVLSRLAVELDEMPYQYEDFSIQTWVENVYRLFTDRNFAIIDKEG
                     KKIGYARSVWAMISMNTRKPADLLALHSGSIVDYVCDEPCPIEKPSRIKVASKEPVAAL
                     VAKYSDIDINGHVNSIRYIEHILDLFPIEMYKEKRIRRFEMAYVAESYYGDELTLFMDD
                     AGEGVYDVEVKKNGSEVVCRSKVIFTEK"
     CDS             complement(11844..12404)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_12"
                     /sec_met_domain="ALS_ss_C (E-value: 8.5e-20, bitscore:
                     60.8, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKLYTIIVHSENFAGLLNQVTAVFTRRQINIESLNVSASSIKG
                     VHKYTITAWTDKDTIEKVTKQITKKIDVLQAHYFTDDEIYQHEIALYKITTPTLEEKPE
                     VSKVIRKYNARIVEVNAVFAIVEKNGMSEEITNLYEELRQLDCVLQFVRSGRVAITTSC
                     FERVNEYLADREAKYRQSKHQES"
     CDS             complement(12437..14188)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg71_13"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.2e-47, bitscore:
                     151.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADNNKKSNFSSLSQGEGRGEALITGAEALMRSLEHQGVKTIFGY
                     PGGSIMPVFDALYDHRKELNHILVRHEQGATHAAQGFARVSGEVGVCLVTSGPGATNTI
                     TGIADAMIDSTPIVVIAGQVGTNFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAV
                     ARAFYVAKSGRPGPVVLDFAKNAQVEKTEYAPTKVDYVRSYLPVPEMEPEAIRKAAELI
                     NGAKRPLVLVGQGVELGEAQQELRAFIEKAGMPAGCTLLGLSALPTNHPLNKGMLGMHG
                     NLGPNINTNKCDVLIAVGMRFDDRVTGKLETYAKQAKIIHFDIDPAEIDKNVKTDVAVL
                     GDCKETLAAVTQLLEPANHQEWIDSFRQYEEVEEEKVIRPELHPAGKALSMGEVVRAVS
                     EATHNEAILVTDVGQNQMMSARYFKYSKERSIVTSGGLGTMGFGLPAAIGATFGRPDRT
                     VCVFMGDGGLQMNLQELGTIMEQKAPVKMILLNNNFLGNVRQWQAMFFNRRYSFTPMMN
                     PDYMKIASAYDIPARRVMTREELAKAIDEMIATDGPFLLEACVEEEGNVMPMTPPGGSV
                     NQMLLEC"
     CDS             complement(14280..14417)
                     /locus_tag="ctg71_14"
                     /transl_table=11
                     /translation="VKLTDEELAARPMTPVTRNREVSKALKAYASMVSSADKGAVRLID
                     "
ORIGIN
        1 tcctctccca cagttcttcc atctgtacat gccgggtgta cttctccgaa agagacttgg
       61 gacggcaact ggcattcaat gtccccgtac gtttaccggc atcctcatcc agcaataagc
      121 cgacagctgt tgcagctccc ttacggggag tacggatgaa aggcctgaaa agtatatctg
      181 tcagcgggtc aaaccacata tgcatggtaa tgatattggt agacacaatc cccgggtcgg
      241 ccgcattcac aacaatacct ttgtgcttga cacgactggc caagtcgatg gtgaacagag
      301 tcaatgccag cttcgtgttg ctatatatag gaatgcgcca aaagtccccc cttcttcccc
      361 ggaggaaaaa atccggaaag tcaagatgac cgatggcata cgtacaagat accatattca
      421 caatacggct cccctctccc atcaatggca gcagcttgcg agtcagcagg taaggcccta
      481 cataattgac actcaccgtc cgttccagtc cgtcctcggt aatgcggcgt tccgtttcca
      541 tggttccggc attgttcatc aacaacgcca acggctctcc ccgcttcaac agatgctctg
      601 caaatgcgac cactgaagcc agagatgcca aatcaatggg agcagtctca atacgcggat
      661 taccggtttc acgcatcagc agttgccgct tgggttcggc agcttggggg tcacggcatg
      721 ccatgatgac ctgatagccg gcagttgcca ctgcgcgggt aatttccatg cccatgccac
      781 cgtctgcccc agttataaca gctaaattca ctttaataat taaaaattga aaattaaaaa
      841 ctaaaaatca gcctttcgct tcgattttct ctatctcctt tttcagacaa ggtggaagtt
      901 cctccttcaa atgctgatgg catgccatct cgatggaata catccgggca atgcaataat
      961 tactatgccg gcagttgcaa cgtgcattct cttcggcacg catgcggttg acgaaccccg
     1021 gctcattgag cagagcgcgc gccatttgca cagcctcgaa gccgtcatcc agcacctcat
     1081 ctatcttgtc cctggaaacc aggccaccca cataaaccaa cggtatcttc aaggcggcac
     1141 ggaatttcaa ggcatcttcc aggaaataag cttccttaaa cggtacgctc ggtatcatcc
     1201 atttgcctac catgcgtaca ccgtatttca accaccagca ggtcatgtaa tgcgtcatgc
     1261 tgcggatagg catttcgccc cgcatgacat acatcggcgc cttactgacg aacccaccgc
     1321 tcaagaccag cgcatgtgct cccgactgct ccagcctccg ggccacctgc atcgtctcgt
     1381 ccagctccat ccctccacgg aaaccgtcgc gcatgttcat cttcaccagc acagccatat
     1441 cactgccggc agccttcatc acttcttcca tcaccatatc cataaaacgc atacggttct
     1501 gcaacgaacc tccgaactcg tctttccgat ggttggtgga cggggacaag aactggctga
     1561 tgagatagcc atgccctgca tgaatctcta cagaatcaaa tccggcctcc cgtgccagat
     1621 tcaccgaacg cccataagca cgcgccatct ctggcagctc atcggcacgc agtccgcgca
     1681 caaaggtagg agagtaaaga ttgaaaccgg aagatgcgcc gacgggcata caaccgcaaa
     1741 tgctcttatg ggacatgttg ccacagtgtc ccaactggat gcctgccgca gccccttccg
     1801 catgtatggc atcagtcagc ctacggagtc cggggataat ctcgggacgc atccacaact
     1861 ggcggtcaaa agacaggccg ctctgagtaa ctgccgcata ggcaacagta gtcataccta
     1921 taccgcccgc cgctaccgac cgatgatagt cgagcaacat gtccgacgga gcgtttccgg
     1981 gacacatgct ctcgaaagca gccgaacgga tggtacggtt acgcaaggtc aacggtccga
     2041 aagtgacggg tgtgaataac ttggattcca tcgttatgag ttataagtta tgaattattc
     2101 attttccatt ttcaactctc cattttccat taataaagaa atggaatgat gcgtttgcgc
     2161 tttcctaccg cctcatcacc aaactcctcc cgataacggc ggtgaatggc atcggcacgg
     2221 ggaacaaggt tggcaaacgt ccaccagacg aacacccagg cggcgggaga agctgtgagt
     2281 atggcaaacc ccgtccattc caccagctca ccgaagtaat tggcagaagt gacgtatcgg
     2341 taaagccctt ttccgggaag ataatgcttc gtatcacccg gcctgcgcag atgacgtatc
     2401 acatagtcgg aatgcaaatt gacgaacata cccgcaaaaa acagaatgat tcccaacaag
     2461 gcatgaggtt tcagcaaata ggcccagcca tcggcataca agccttcggg agcaaaatag
     2521 aacaaaccgc ccgcctgcat catcccgttc aaaaggttga agacgatacc catcgccata
     2581 atagctaccg gcatccggct tttacctttc agcaggaacg gaaaaataaa ggcccgctga
     2641 agatagtgca actgaaacag caggaaaaag aaatataccg gcacggcaaa tcccgctcca
     2701 ctcttccccc acaacccaaa catgacgatg aataccggcg cttccataag cacccacgcc
     2761 agtttattat tgatggagat tccccacgag gcagtacgga acatgccata acccgctttg
     2821 acaaaataga gcgcaataaa gacaaccaat gccacagcac tcattaccca cagaaatatc
     2881 tgaaaagttt cctgattcat agttctttat ttatgcgaag caaagataaa gaaaactcac
     2941 aacaaacaaa tcgttttccc cggataattg ttttttcatg caaaaaacag tgttttttta
     3001 ctgagaagat taagcagtag agatacaaaa atctaatcgt tccatcatgg agtaaatttc
     3061 attccaccat ggagaaaaaa tcgttccacc atggtggaac gatttttccc ccgtgatgga
     3121 acgatttaaa agatacaagt ctaatcctta ccgtttctta atgggcacat aagtcacctc
     3181 atccaaaaca ttcttatagg caggacggat aatacgctta ccttcaaagt tcaattcttc
     3241 attgcgatgt gcacaccaac cgacaatacg tgccatagca aacaaaggcg tgaagatttc
     3301 ctgcggcagt ccaatcatct cgtagacaaa gcccgaatag aaatccacat tgctcgaaac
     3361 cgtctttcca ttattcttca cacggccaaa cacatcaatg gcgcgctcct cgagcagttc
     3421 aaggaaagcg aactcacgtt ctttcccttt ttcgcgggca aggtcgcggg caagctcctt
     3481 cagcagaatg gcgcgcgggt cggaaatggt atagacggca tgtccgatac catatatcaa
     3541 accggtcttg ttatagactt ccttgttgag catgcgggtg aagtaagtat caatctcatc
     3601 cacgttcgtc cagtcctgaa tgttttcctg cagatggtgg aacatatcgg caacctgaat
     3661 attggcacct ccatgaagcg gccctttcaa ggaaccgata cctgccgcta tcgaagagta
     3721 agtatccgtc ccggtagaag aagtgacacg tacggtaaaa gtggagttgt taccaccacc
     3781 gtgctcggcc tgaagaacca acagcaggtc gagtgtgcgg gcatccagct ccgtgtagtc
     3841 cttcttcagc atatagagga aattctcggc aatggaaagg ttttcctgcg gatggcggat
     3901 atgcagtgaa cggccatggg tggcatggcg aagcatgtta taggcatacg caatgatggt
     3961 cgggaatttc gaaataagct caatgctctg ccgcatcaga ttatcgcggg aagtgtcatc
     4021 ggcatccggg tcgaaacggt acatctcgag cacgctgcgc gccaggatgt tcataatgtt
     4081 gtttccttca agttcaatga tattcatctt ggtcttctgc tccagcggca tgttgtcgtt
     4141 gatgagttca cggaaagaag agagttcttc cttgtcgggc aggcgaccgg aaagcaacaa
     4201 gtaggcaatt tcctcaaaac cgaaacgctt ctctttgatg atggcgtgtg ccaagtcatc
     4261 cacatcataa ccgcggtaga acaatttgcc gggaataggc ttcagccctc caccggggat
     4321 gcgttcatag ccgaccacat tgcctatttt ggtcaacccc accaagactc ccgtgccgtc
     4381 ctcattacgc aaaccgcgct tcacatcaaa cttcctaaac agttcattct caatccgggt
     4441 agcttccttc aaatcttcgg aaagcttgta aatcagatac tccttcttca taatcgtttc
     4501 gttttattcg ttattcccat tttctattct ccttacaatc tcccgggtga aagtcgaagt
     4561 ggacagcgag acgctacccg gcataaaacg ggccaagtcg gcagtagcac gggcttctgt
     4621 gaaactttcc tccaaggcgt tctctataag agaggctgct tccttccagc ccagatattc
     4681 aagcatcatc acagcggaaa ggatgatgga acagggattc acaatgtctt tcccggcaat
     4741 gttcggagcc gtcccgtgag tagcctcaaa aatggcatgc cccgttttat agttgatatt
     4801 cgcacccggt gcaatgccga tgccgcctac catggcagcc agttggtcgg acacataatc
     4861 accgttcaga ttcaacgtgg cgatcacgga atattcttcg gggataagca acgtgttctg
     4921 caagaatgca tcggcaatgc agtccttgat gaccagacgc ccttctgcca gctctttacc
     4981 aaactcacgt tctgccagtt cgtaccccca cttcttaaaa ccgccttccg taaatttcat
     5041 gatgtttcct ttgtgtacca aggtcacgga aggcagatga tgctcaagcg cgtatcggca
     5101 ggcggcacgc accaagcgct ctgttccttc tcttgaaacg ggcttcacgc caaacgagga
     5161 ggtttcggga aaacggactt ttgtcacccc catgtcatca cggagaaaac gatagaactt
     5221 ttcagcctcc ggagttccgg cttcccattc gatgcctgca taaatatcct cggtattctc
     5281 acggaatacg cacatatcca ccttctgcgg ctctttgagt ggagaaacaa tgcccttata
     5341 ccaacgtacc ggacgttggc agacatacaa atcaagtgtc tgacgcaagg ctacgttcaa
     5401 ggaacggata cctccgccga cgggagttgt caaaggacct ttgatgccca ccttataggt
     5461 gcggaaggct tccatggttt cgtccggcaa ccaggagccg gtttcgtgga aagcacgttc
     5521 tcctgccagc acttctttcc attcaatgcc acgccggtcg ccataggatt tcttgacagc
     5581 ggcattcacg acagcctgca tggatggggt cacttctgct cccactccat cgccggtaat
     5641 aaaaggtaca gtaatttttt ccatattcta tcttgcatta agtgcagaac cggcccggaa
     5701 ccaagctatc tgctgttcgt tatacgtatg ttgtacttca aaactttctt tactcccatc
     5761 ctcgtgatga agaaccacct tcaacgtgcg tcccggagca aaatctttca gccccatgac
     5821 agaaatcagg tcgcgttccc gaatcttgtc ataatcggcc ttatccgtaa aggtcagcgc
     5881 caacatgcct tgtttcttta agttcgtctc atggatacgg gcaaaactct tcgccaaaat
     5941 gacgcgtaca ttcaggaagc gcggttccat ggcagcatgc tcacggctgg aaccttcacc
     6001 ataattctct tcggcaacga ccatggaagg gataccttcg gacttataca gcttcgcagt
     6061 gcctgacact gttccatagg tattggtgga gcggttccaa accttgttcg tctctccatt
     6121 gaaagcattg acagccccca tcagcatatt gtccgaaata ttctccaaat gtccccggaa
     6181 acggagccat ggccccgcca tggaaatgtg gtcggtggta catttcccct gtactttaat
     6241 caataaaggc atgtccagca aatccatgcc atcccaggca gggaagggag tcagcagttg
     6301 caagcgctgt gaatgaggat tgaccgtaat ttccgtctgt cctttgcctg gagcaatgta
     6361 tccttccttt cctcctataa acccgtgtgc cggcaattct tcaccgaccg gttcggacag
     6421 tttcacaacc tctcctttgg cattgaccag cgtatccctc aacgggtcga aacaaaggtc
     6481 accggcaatg gtcagcgcca tcgttatctc cggggaagcg acgtaagcaa aagtgttggg
     6541 atttccatcg gcacgtttgg caaaattacg gttaaaagag gtgacgatgg aatttttgcg
     6601 ttcggggtca tcagtatggc gcttccactg gccaatacaa ggtccgcagg cattcgccat
     6661 tatcgttgcg ccaatatctt cgaaagcggc aatcatgccg tcgcgttcag cagtggcacg
     6721 tatctgctcc gagccggggt tgacaatcag cgaggaagca accttcaaat tcttttcctt
     6781 tacctgccgg gcaagggagg ccgcgcggct caaatcctga taggacgaat tggtgcacga
     6841 ccctatcaga ccgacttcca tccggcgggg atagttattg gttatcacta cctcggcaaa
     6901 tttcgatatc ggtgttgctg catccggcgt aaagggcccg ttgatatacg gttccaataa
     6961 cgagaggtct atttcaatga tgcggtcgta atatttttcc ggatttgcca gcacttcgtc
     7021 gtcggcgcga aggtcggcag ctacggaagc agccatttcc gccacttctt cacgtccggt
     7081 agctttcaag taggtaccca tacgctcatc gtaagggaaa agggaggtag tcgcccccac
     7141 ctctgccccc atattgcaga tggtagcctt tccagtggca gacaatgaag cggttcccgg
     7201 tccaaaatat tcaatgatgg cattggttcc cccttttaca gtaagaatac ccgccaactt
     7261 cagaataacg tctttgggag ctacccagcc actcaattta cccttcaagt gtacgcctat
     7321 cagacgcggc tttttcagtt cccattccat gccggtcatc acatccaccg catcggcacc
     7381 acccacacca atggccacca tgcccaaacc tccggcattg ggcgtatgag agtccgtgcc
     7441 taccatcatt ccacccggaa atgcgtagtt ctccaatacc acctggtgaa taatacctgc
     7501 tcccggctgc caaaaaccta tgccatagcg ggaagaaaca tcacggagaa aattatagac
     7561 ctcctcgttg gtcttcgtag cagtcgcaac atcttctttt gcacctttat atgcttgaat
     7621 caaatggtca caatgcacag tggaaggcac ggcaacctgc tcacggcctg cattcataaa
     7681 ttgcaataag gccatttgag ccgttgcatc ctgcatggcc acacggtcgg gacggaaatt
     7741 cacatagtct tctccccgtc tgtagttctt cactttatcc ccatcataca aatgagcata
     7801 caaaattttc tccgctaaag tcatcggacg ccgcagtacg ttccgtacgc gttctatctt
     7861 ctccgaataa gcagcataaa acgttttgag catcgttaaa tcatatacca taaccactat
     7921 tttttagttt ttcattattg taaagattac aaattaatat cataaacaaa taaaaaggct
     7981 gaatagttta acaaaataaa gcattttttc cgtcggaagc gaagaatgat tacctttgca
     8041 accatgaagg aacaagattc aaatagtcct attattcacc tccagcagca acaagttttg
     8101 ctgcgcatgg aatacgaata cgaaaaagag gaattcaaac gccaaaccga aaacatggga
     8161 gttgcccgga aagtgaaacg gggactttgc tggtatcctg ccactccggg acgaagttac
     8221 tataattcac tgaatcaatt agtaatagaa attacacaca cagaaaatac cgatatagaa
     8281 cataattttg agttcggccg tcccgtatgt tttttccgcc agtctgctga tggaaaaata
     8341 acctatatga acttcaccgc taccgtaagc tatgccgacg agacacggat ggtagcgata
     8401 atgcccggag ccggtgccgt tatggaagtg caggaaacgg acaacctcgg cgtgcaactt
     8461 tatttcgacg aaacatccta tcggaccatg ttcgaagcct tggaagatac gttacgctcc
     8521 aaaggcaacc gcctggccga attgcgggac atattgctgg gaacctcgaa agccggtttc
     8581 cgagagctct atcccgtacg gtttccctgg ctgaactcca cgcaggagac agctgtaaac
     8641 aaagtgctgt gtgcccgcga cgtggccatt gtacacggtc ctccgggaac cggaaaaacg
     8701 accaccttag tggaagccat ctacgaaacc ctgcatcggg aaccgcaggt actggtatgt
     8761 gcccaaagca atactgccgt cgactggatt tcggaaaaac ttgtggaccg tggcgtcaat
     8821 gtcctgcgta tcggcaatcc gacccgtgtc aacgacaaga tgctttcctt tacctacgag
     8881 cgtcgtttcg agaaccatcc gctttatccg gagctgtgga gcatccggaa aaatctccgt
     8941 gaactgggca gccgtgcccg ccgtggcagc tatgacgaac gcgaaggagt acgcagccgt
     9001 atgagccgcc tgcgcgaccg cgccaccgca ttggaaatac aaatcaatgc agagcttttt
     9061 gatggggcac atgtcatagc ctccacgcta gtaagcagca atcaccggct gctgaacgga
     9121 cgccgtttcg gcaccctttt cattgatgaa gcagcccagg ccttagaagc tgcctgctgg
     9181 atagctatcc gaaaagcaga ccgcgtggtg ttggcgggtg accactgcca acttccgccc
     9241 actataaaat gctacgaagc tgcccgtgga ggtctggaac gaacattgat ggagaaagtg
     9301 gtgtccaaca aacctgccgt tgtctctttg ctgaaagtac aataccgcat gcacgaggaa
     9361 atcatgaaat ttccttccca atggttttat aatggcgagt tggaagccgc tcccgaagtg
     9421 cgttaccggg gcatcctgga ctgggatacc cccatccact ggattgacac ctccgaaatg
     9481 gatttcaaag aagaatttgt gggagagact ttcggacgca tcaataaagc ggaagcggac
     9541 ctgctcctat cagaactgaa aatctacatc aaccgtatcg gtggcagccg cattctggaa
     9601 gaaaaaatag acttcggcat catctcccct tacaaggcac aagtgcaata tctccgcagc
     9661 aagataaagg cagacgcttc actcaagcct tatcgcagct tgttcactgt aaatacggtg
     9721 gatggcttcc aagggcaaga gcgcgatgtt atcttcatca gccttgtccg tgccaacgaa
     9781 gaaggacaga taggattcct gaatgattta aggagaatga atgtagccat cacccgggca
     9841 cgtatgaagc tggtgatatt gggagaggca gagacgctga aacatcacgg tttttaccgg
     9901 aagctattgg agtttattca aaatataggg aatcaataat aaagaaatac cccctccggt
     9961 aacaccgaag agggtatttc acctatttat ataaagctga ttaattgttt tccggacgaa
    10021 gtttacgaac tgtaacagct gtctgccaca tttcgctttc acgcaaggct ttcaattctg
    10081 cattcagctt ctcacgataa tcgggtttgg agttactgtc gatagaaatc tgagcttcgt
    10141 tgcccgactt cacacttgca tacaatttct gtacaaccgg cttgatggca tcatggaacg
    10201 gggtcatcca atccagcgca ccacgctgtg ccgtagtaga acagttggca tacatccagt
    10261 ccataccgtt cttggcaaac aatggcatca aagattgagt caactcttcc actgtttcat
    10321 tgaatgcttc agaaggagta tggccgtttt cgcgcaatac ttcatactga gccaacagca
    10381 atccctggat agcacccatc aatgaaccgc gttcaccggt caagtcggaa gtggcttcgc
    10441 ggatgaaagt tgtctcgaac aaatatcccg aaccgatgcc gatacccagt gcaatcgtct
    10501 tgtcaaaagc cttacccgta gcatcctgat agacggcata tgatgagttc aagccacgac
    10561 cctcaaggaa catggtacga agtgaagtac cggaaccttt gggagcaacc ataataacat
    10621 caatatcttt aggaggaacc acgccggtac ggtcgttcca ggtaatagca aaaccatgag
    10681 agaagtaaag agcctttccg ggagtcaaat aaggtttgat agtcggccat acagacatta
    10741 cagctgcgtc agacaacaga cacatgatga tagtaccttt ctgacaagcc tcttcgatgc
    10801 cgaacaaagt ctcacccggt acccatccgt cagccacagc cttttcgtat gtcttacccg
    10861 gacgttgtcc tacaatcaca ttgaaaccgt tatcacgcaa gttgcaagcc tggcccgggc
    10921 cttgtacgcc ataaccgatt actgcaattg tttcatcttt caaaatctca cgtgcttttt
    10981 ccaaaggaaa ttcttcgcgg gtcattacat tctcaataac accgccaaaa ttcaattgtg
    11041 ccattttttg ttttaatttt tatttgtggc ttacgccaac gttgataaat ttatttattt
    11101 ctctgtaaat atcactttag agcgacagac cacttcgctg ccattctttt tcacctccac
    11161 atcgtaaacg ccctcaccgg catcatccat gaacaaagtc aactcatccc cataatagct
    11221 ttcggctaca tatgccattt caaaacgacg gatgcgcttc tccttataca tctctatcgg
    11281 gaacaaatca aggatatgct cgatgtaacg gatgctgttc acatgcccgt taatgtcaat
    11341 atcactgtat ttggctacca aagcagcaac cggttccttt gaggccacct ttatccgcga
    11401 aggtttttct atcgggcaag gctcatcgca aacataatct acaatgctgc cactatgaag
    11461 agccagcaaa tctgccggct tacgggtatt catgctaatc atcgcccaaa cggaacgtgc
    11521 atacccaatc ttcttaccct ccttatcgat gatagcgaaa ttacggtctg taaaaaggcg
    11581 atagacattc tccacccaag tctgaatgga gaaatcttcg tactgataag gcatttcatc
    11641 cagttcgaca gccagacggg acaataccca agtataattg tcctcgttta gagtcgcgat
    11701 gccaaaaccg cggtcgctgg catggaaacc cgcacaattc aacaaatggt tgcccaatac
    11761 tcccattgtc agccgtccgg taaagtcgac atgaaacggt tcggcaacaa acttgtaggt
    11821 acctatttta ttgttctcgc tcatcatgat tcctggtgtt tactttgacg atattttgct
    11881 tcacggtccg ccagatattc attgacacgc tcaaagcagc tggtcgtaat ggctacgcga
    11941 cccgaacgga cgaactgaag tacgcaatcc aactggcgca actcctcata aagattggtt
    12001 atttcctcac tcatgccatt cttctcaaca atggcaaata cagcattcac ctccacaata
    12061 cgggcattgt acttacggat tactttggac acctccggtt tttcttccag cgtaggggtc
    12121 gttattttat aaagggcaat ctcgtgctga tagatttcat catccgtgaa ataatgggct
    12181 tgcagcacat ctattttctt ggtaatctgc ttggtcacct tttcaatggt atccttatcc
    12241 gtccaagcgg taatggtata tttatgtacc cccttgatgg aggaggccga tacattcaaa
    12301 ctctcgatgt ttatctgccg gcgggtaaac acagccgtca cctgattcag caaaccggca
    12361 aagttttccg aatgaacaat gattgtatat agttttttat ccatagatag agtaaattct
    12421 ttaatttcgc atgacttcag cattccaaca acatctgatt gaccgaaccg cccggaggtg
    12481 tcatcggcat tacatttcct tcttcctcca cacaagcttc gagcaggaac ggtccgtcag
    12541 tcgctatcat ctcgtcaatc gcttttgcca gctcctcgcg ggtcattacc ctgcgtgcag
    12601 gaatatcata tgccgaagca atcttcatat aatccggatt catcatcgga gtaaacgaat
    12661 aacgacgatt gaagaacatc gcctgccatt gacgaacatt gcccaagaag ttattgttca
    12721 acagaatcat cttcaccgga gccttttgtt ccatgatggt acccagttcc tgcaggttca
    12781 tctgcaagcc gccgtctccc atgaatacgc ataccgtgcg gtccggacgt ccaaaagtgg
    12841 caccgatagc tgccggaagg ccgaagccca tagtacccag gccaccggaa gtaacaatgc
    12901 tacgttcctt gctgtatttg aaataacggg cggacatcat ctgattctgg ccgacatcag
    12961 tcaccaatat cgcctcgtta tgggtagcct cactcacagc acgcaccacc tcacccatgc
    13021 ttagcgcttt tcctgccgga tgtaattccg gacggattac cttttcctct tccacttcct
    13081 cgtattgccg gaaactgtca atccattcct gatggttggc gggttccagc aattgggtaa
    13141 cggcagccag tgtctctttg caatctccca ggacagcaac atcagtcttt acattcttat
    13201 ctatttcggc agggtcaata tcaaagtgga taatcttcgc ctgcttggca tatgtttcca
    13261 atttacccgt cacacggtca tcaaagcgca tgcctacggc gataaggaca tcacatttat
    13321 tggtattgat attgggcccc aggttaccgt gcataccaag cattcctttg ttcaacggat
    13381 ggttcgtagg taatgcggaa agtcccaata aagtgcatcc ggcaggcatt ccggctttct
    13441 caatgaaagc acgaagctct tgctgggctt ctcccagctc cacgccttgt ccaaccagca
    13501 ccaaaggccg tttcgcacca tttattaatt cagcagcctt ccgtatggcc tccggctcca
    13561 tttcgggaac gggaagatag ctacggacat agtccacctt agtaggcgca tattctgttt
    13621 tctccacttg ggcgttttta gcaaaatcca gcacgaccgg tcccggacgt ccgctctttg
    13681 ccacatagaa agcacgtgcc actgcccagg ccacatcttc tgcacgacga atctggtaac
    13741 tccatttcgt gataggctga gtaatgccta ccaagtccac ttcctgaaat gcatccgtac
    13801 ccaagaagtt cgtccctacc tggccggcaa tgacaacgat aggcgtactg tcaatcatgg
    13861 catctgcaat gcccgtgata gtattggtag cacccggtcc actggtaacc agacaaacgc
    13921 caacctcgcc tgatacacgt gcaaagcctt gtgccgcatg ggttgctcct tgttcatgac
    13981 gaaccaagat gtggttcaat tccttccgat ggtcgtataa ggcatcgaat accggcatga
    14041 tgctccctcc cggataaccg aaaatagtct ttactccctg atgctccaga gagcgcatca
    14101 atgcttctgc gcctgttatt agagcctcac cccgaccctc tccttgggag agggaggaaa
    14161 agttactctt tttattatta tcagccatac tttatctatt cattatattt aaaagctcaa
    14221 tagtagcttg aaaaatttgt ttcattctct cctcccctcg ctttcggaaa ggggggcttt
    14281 taatcaatca gcctcacagc ccctttgtca gcggaactca ccatactggc atatgctttc
    14341 aatgctttgg agacttcacg gttgcgggtt accggagtca tagggcgtgc tgcaagctct
    14401 tcatccgtca acttcac
//
