LOCUS       gnlProkkaFDPLMDMP_24   21557 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FDPLMDMP_24.
ACCESSION   gnlProkkaFDPLMDMP_24
VERSION     gnlProkkaFDPLMDMP_24
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-18 03:53:43
            Original ID  :: gnl|Prokka|FDPLMDMP_24
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 149
            Orig. end    :: 21706
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..21557
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:11557]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11557
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..21557
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..21557
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             98..367
                     /locus_tag="ctg24_2"
                     /transl_table=11
                     /translation="MYLDSAKKKELFEKYGKSATNTGSAESQIALFTFRISHLTEHLKV
                     NHKDYATERSLKMLVGKRRRLLDYLIKTDIERYRAIIKELGIRK"
     CDS             527..1108
                     /gene_functions="other (smcogs) SMCOG1148:hypothetical
                     protein (Score: 92.5; E-value: 6.5e-28)"
                     /gene_kind="other"
                     /locus_tag="ctg24_3"
                     /transl_table=11
                     /translation="MGNNKIIGAKIKNIRESKQLSIEEVAERSGLGIEQIERIEGNLDF
                     PSLAPLIKIARVLGVRLGTFLDDQAELGPVVCRKKDSEADGIGFTNNATQGHKHMDYHS
                     LSQDKSGRHMEPFLIEIAPSEEGEDFILSTHEGEEFIYVLNGVVEINYGKNTYILEEGD
                     SIYYDSIVAHHVHAAADNKARILGVVYTPY"
     CDS             1121..2770
                     /NRPS_PKS="Domain: AMP-binding (11-443). E-value: 1e-97.
                     Score: 319.2. Matches aSDomain:
                     nrpspksdomains_ctg24_4_AMP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     380.5; E-value: 1.7e-115)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg24_4"
                     /sec_met_domain="AMP-binding (E-value: 1.7e-108, bitscore:
                     355.0, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELHNRTLGQWLEHWAENTPDKEYIVYSDRDLRFTWSEFNKRVDD
                     MAKGMLAIGITHGTHVGVWATNVPDWLTFLYAGAKIGAVLVTINTNYKQSELEYLVENA
                     DIHTMCITDGVFDGSYVDMVYTMLPELKTSQRGYLKSERFPRLRNVVYIGQEKYRGMYN
                     TPEMLLLGQNIKDETLEAAKARVNCHDVVNMQYTSGTTGFPKGVMLTHYNIANNGFLTG
                     EHMKFTADDKLCCCVPLFHCFGVVLASMNVLTHGCTQVMVEKFDPLLVLASIHKERCTA
                     VYGVPTMFIAELNHPMFEMFDLTSLRTGIMAGSLCPVELMKTVDEKMHMRVTSVYGLTE
                     TSPGMTHSRIEDPAEVRYNTVGHEFEFTEVRVIDPETGEECPVGVQGEMCNRGYNNMKG
                     YYKNEAATNEAIDKDGFLHSGDLGVRDENGNFRITGRIKDMIIRGGENIYPRELEEFLY
                     HFPGVKDVQVAAVPSKKYGEEVGAFIILHDGVTATEEEVKDFCRGKIARHKIPKYIFFV
                     DTFPMTGSGKIQKFKLKDLGLKLLQEQGITPA"
     aSDomain        1154..2449
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg24_4_AMP-binding.1"
                     /evalue="1.00E-97"
                     /label="ctg24_4_AMP-binding.1"
                     /locus_tag="ctg24_4"
                     /protein_end="443"
                     /protein_start="11"
                     /score="319.2"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="LEHWAENTPDKEYIVYSDRDLRFTWSEFNKRVDDMAKGMLAIGIT
                     HGTHVGVWATNVPDWLTFLYAGAKIGAVLVTINTNYKQSELEYLVENADIHTMCITDGV
                     FDGSYVDMVYTMLPELKTSQRGYLKSERFPRLRNVVYIGQEKYRGMYNTPEMLLLGQNI
                     KDETLEAAKARVNCHDVVNMQYTSGTTGFPKGVMLTHYNIANNGFLTGEHMKFTADDKL
                     CCCVPLFHCFGVVLASMNVLTHGCTQVMVEKFDPLLVLASIHKERCTAVYGVPTMFIAE
                     LNHPMFEMFDLTSLRTGIMAGSLCPVELMKTVDEKMHMRVTSVYGLTETSPGMTHSRIE
                     DPAEVRYNTVGHEFEFTEVRVIDPETGEECPVGVQGEMCNRGYNNMKGYYKNEAATNEA
                     IDKDGFLHSGDLGVRDENGNFRITGRIKDMIIR"
     CDS_motif       1703..1753
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg24_4_0001"
                     /evalue="2.10E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg24_4"
                     /protein_end="211"
                     /protein_start="194"
                     /score="23.3"
                     /tool="antismash"
                     /translation="QYTSGTTGFPKGVMLTH"
     CDS_motif       2264..2350
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg24_4_0002"
                     /evalue="1.40E-03"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg24_4"
                     /protein_end="410"
                     /protein_start="381"
                     /score="11.2"
                     /tool="antismash"
                     /translation="PVGVQGEMCNRGYNNMKGYYKNEAATNEA"
     CDS             2864..3682
                     /gene_functions="regulatory (smcogs) SMCOG1287:AraC family
                     transcriptional regulator (Score: 53.5; E-value: 3.3e-16)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg24_5"
                     /transl_table=11
                     /translation="MDGINTLRYSDLFLAMYFDGGKSCLHRNHSHVLVYVYSGEMVIDE
                     KGQITRLHKGECAFIRKDFSVQMTKQAWNGEQFKAIFLMFTMKFLRDFYSKLDRNTLPK
                     DAKRDQVSLYKLPSNRPDIVSLFESMTPYFNSKIQPTDELLQLKMVEGVYVLLNTDKNL
                     YASIFDFTDPWKIDILEFMERNYMNDISMEEIANYTGRSLSTFKRDFKKCSALSPREWL
                     IRRRLEAAHGLIRKGGRKVSEICFEVGFKNLSHFSKIYKIAYGVPPTEDI"
     CDS             3792..4547
                     /NRPS_PKS="Domain: PKS_KR (8-162). E-value: 2.2e-16. Score:
                     52.1. Matches aSDomain: nrpspksdomains_ctg24_6_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     227; E-value: 4.4e-69)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg24_6"
                     /sec_met_domain="adh_short (E-value: 2.1e-37, bitscore:
                     121.1, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 3.6e-31, bitscore:
                     101.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKTTEEKVALVTGSAMGIGLACAEAFAKAGYITVLADIREPREQ
                     VEKLVAEGHKAVAYRCDVSNTQAVKEMIDWIVATYGRLDAALNNAGIQTPQRPMAEITD
                     DEFDRTVAVDLKGVWNCMRYEILQMLKQGGGAIVNTSSQGGVTGFPGQAAYIACKHAVI
                     GLTRTAAIDYAAKNIRINAVCPGVIRTPMAEDLMRRDPSLEKELVRDIPAGRLGKPEEI
                     ANAVLWLCSPQASFVDGHALLVDGAFSIH"
     aSDomain        3816..4277
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg24_6_PKS_KR.1"
                     /evalue="2.20E-16"
                     /label="ctg24_6_PKS_KR.1"
                     /locus_tag="ctg24_6"
                     /protein_end="162"
                     /protein_start="8"
                     /score="52.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VALVTGSAMGIGLACAEAFAKAGYITVLADIREPREQVEKLVAEG
                     HKAVAYRCDVSNTQAVKEMIDWIVATYGRLDAALNNAGIQTPQRPMAEITDDEFDRTVA
                     VDLKGVWNCMRYEILQMLKQGGGAIVNTSSQGGVTGFPGQAAYIACKHAV"
     CDS_motif       4203..4262
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg24_6_0001"
                     /evalue="2.10E-04"
                     /label="PKSI-KR_m4"
                     /locus_tag="ctg24_6"
                     /protein_end="157"
                     /protein_start="137"
                     /score="13.8"
                     /tool="antismash"
                     /translation="VNTSSQGGVTGFPGQAAYIA"
     CDS             4778..6151
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 2-Hacid_dh_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg24_7"
                     /sec_met_domain="2-Hacid_dh_C (E-value: 1.7e-08, bitscore:
                     26.3, seeds: 135, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLAEFGRKEIEIAEHEMPGLMALRQKYADQKPLKGARITGSLHM
                     TIQTAVLIETLVALGADVRWASCNIFSTQDHAAAAIAADGVPVFAWKGETLEEYWWCTD
                     MALRFPEGKGPHMIVDDGGDASLLIHMGYRAENDAETINRKGGNHEEQVILDTLNRILQ
                     EDNGRWHRTVAEMKGVSEETTTGVHRLYQMMEKGELLVPAINVNDSVTKSKFDNLYGCR
                     ESLADGIKRATDVMIAGKVVVVAGYGDVGKGCSHSMRSYGARVLVTEIDPICALQAAME
                     GFEVTTMEEAVKEGNIFVTTTGNCDIITIEHMTQMKDQAIVCNIGHFDNEIQVDKLVNY
                     PNIKHTNIKPQVDKYTFPNGNSIFLLAEGRLVNLGCATGHPSFVMSNSFTNQVLAQMDL
                     WQMAYEVGVYRLPKRLDEEVARLHLERIGVKLSTLSQKQADYIGVPVEGPYKADHYRY"
     CDS             6254..7381
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 98.1;
                     E-value: 1.1e-29)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg24_8"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1e-18, bitscore:
                     59.8, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFAILSPIYPYRGGIAQFSGMLYTELVKEGHEVKAFNFKRLYPD
                     ILFPGKTQYVEAGDRAIEIESVRVLDSVNPVSYFSTVNAIRSYAPDVLIISYWMSFFVP
                     GYAHVANRMKKHCKVITLIHNAIPHEPRFFDKPLASLLFKQCHGFIVMSDNVRYDLRKL
                     YPGAKYIQNPHPLYNHFGSKINKNEACRKLGIHPSKKNLLFFGLIRDYKGLDLLIEAMG
                     QLNEDYHLIIAGECYGSFEKYQALIDASPAKERIFVHCEYISDEEIPIYFSAADALVLP
                     YRSATQSGVVSVAYNYDLPMLSTPVGDFKNSIEKPGTGIVVPEISATALAQGIEELFTP
                     SQQATIPANISKEKAALSWETLTRKLLDFINSGFI"
     CDS             7525..8367
                     /locus_tag="ctg24_9"
                     /transl_table=11
                     /translation="MRKQILIICIYIGELPWYFKFFLKSCSFNKDIDFLILCDQDMTSK
                     GISNNIKIKRYDLQDFKKDVHRSLNINTPIQNGYKLCDFKPAYGYIFSRYIEGYDFWGY
                     CDIDVIFGNIRAFITENILSKYEIITVRQDYLSGCFTLFKNEHKTNTLFMQSKNYLKVF
                     LSEKNFCFDETNFAFDEFAKSKDAYNINTEIESMTHVVLKMKDKGLLKPYFNLHILEGL
                     PGNMTWKKGTLLYKNKYEVLLYHLIFFKDFFKQYNKSTVPDEFIIEQTRITEISAFSY"
     CDS             8379..8708
                     /locus_tag="ctg24_10"
                     /transl_table=11
                     /translation="MEDLFKTYKRNVALGINIDNLYYIYDRSSNNILEVSKYIYENLDY
                     LSLFESSIENIFINKKLSANYFNQWIPKLNTLKQNIDNTLSELTLNITETCNFRCKYCF
                     FNKKK"
     CDS             8729..9763
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg24_11"
                     /sec_met_domain="TIGR04085 (E-value: 9.6e-11, bitscore:
                     34.3, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 2.3e-07, bitscore: 23.6,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLKTAKKAVDFYFKNSNNCNHQISFIGGEPLLKFNLIKKIVEYI
                     KTFNNKVSFTIITNGSLLKEDILNYLIENMFHITISFDGEKEIQGLNRLSKDKKNSFDI
                     VYNNIRKIQLNNTRYFEQYVTINSVYSINITSSLSEFTNYLEAHFKNKFAINIQSSEIN
                     DEYTKFHNNFTKSFLSIYENIHIQGFENSSPPLFIISSDLHKKMMFFSRRSNNILQEET
                     RFIPIKSCLPYLNKIYISPTGDIFMCSDLYYIKGFNIGNIDKSIELNKLQDIMTQYTNF
                     RNKTCKKCWVYRFCDFCFYTLYASKERKGINKYCKIIKYDYAQVIKSYIKILKSNGSAF
                     DIYY"
     CDS             9784..9957
                     /locus_tag="ctg24_12"
                     /transl_table=11
                     /translation="MKQKTKKISWENFKDEIKVISAGQQKLLTGGGCACCICSPGNGNS
                     GLGGSTKASISH"
     CDS             10001..11557
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_13"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 5.7e-08,
                     bitscore: 25.2, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.8e-15, bitscore: 49.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.1e-09, bitscore: 31.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 9.2e-09, bitscore:
                     27.9, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKLEYKNSPVLGFILNSKYYLYDRYSNSIFTVPRIFFEYLDDLI
                     SLDTDEFTQKYHNIFSKEEIIDLFKTLDYCQNDKKLIKPNRIPKFTISSIYSNAKKVEK
                     KLKKELTFLCINITEECNLRCEYCIFSGKYTKSRRHNSNNQIEWNYIEKGVNLFLEHST
                     DSNIRKIGFYGGEPLLYFDIIRKTINYVRSKCDNAIFTITTNATLLKDKILSFFVENNV
                     EITISLDGPQNIHDKNRIFPNGVGSFNTVIKNIESIKRLHHDFFENNIKFSATLSPGKY
                     KIKDLIDFFTYDMFPTLKRADLPLSLNYINYEENKYLSEVKYLDWTKKTENEIFKLYKK
                     IHIKGINKTSEIPAVLRALPIHREMMYINLRSNIAFDEFKFFWPNGACIPGMRSIFLNS
                     KGIFLPCEKLNSETEFCIGDVSTGFDIKKISQLIADYSREIAPLCSNCWAFRFCGECWT
                     TAVKNGQISKDFRSQYCSYIKSYWARRLFLYTEIIEKNPKAFSYQGSIDYPEFMSHMIN
                     E"
     CDS             11570..12697
                     /locus_tag="ctg24_14"
                     /transl_table=11
                     /translation="MNKYITYLFLLLLSCGKPQDNNGIFTMDLSKDDLPKTTVSLDDYT
                     TKWTRIDLETTEDCLLDPSFNIYPTDHFIVAYSFNRILVFDHTGHFIREISHFGEGPDE
                     HGLLFNCTVNPTSEQLVFVEMGNTEEIIRYDLSSGKQLTAIPIVAKKQLCDLLFIKDST
                     LVCFPYAGNQKQMAYKQNLAGEWIGTPPIPISEPAGPYNPIPISLFQVDNQWIYKGIYE
                     DTLYLVNNLEPFARFSRKDISPSKTELEVQNSSFINHLFTSNGMSLFGYPQYQLKEVSE
                     GIFDLVLVDFRAFLFNHADKQILEIEKMNCPPLSIIYEQKNLNDLFMLISSRNPKKLVL
                     KVPAEFMGKEEDENPVLFISDLIYPKKKQPTRGKP"
     CDS             complement(12860..15364)
                     /locus_tag="ctg24_15"
                     /transl_table=11
                     /translation="MRSIMSKWGKHIAAIAVFLVLTVIYFSPAVFEGKVVRQGDTEKAI
                     GMGNSQMDEYEKTAQPGEFSAWSDAMFGGMPYVSGYGNPAPRFPGYLLVEKPLKALGYM
                     DAGMVFTGFVCFYILMCVMGVNWWLAIAGAIAFALASYNLIIIEAGHVTKAYVIAYMPL
                     TLAGMALLFKRKYLWGAVVFLLGVAFSIANTHLQITYYLLLLCFFVYLGYLFNKLKEKA
                     YKELGTVTAIMAGCVILAVLPNAQNMYAQWDLGQNSIRGATELTTTTPSGEKISSGLDK
                     DYAFAWSYGKGELLTLLVPNAYGGSSGGMLGPDSELYKELRAKGAQVGKEVQAPTYWGE
                     KTFTSGPVYFGALVCFLFVLGMFVIRNPMKWWLFGGSVFLILLALGRNFDSFNDFMFHY
                     LPMYNKFRTVEMALVIPGMVFPIIAIWGLKEVLSETVSDALLKKGLIAALAITGGISLI
                     LWLMPSMLLDFRSSFDAQYQLPDWYYNALLMDRASLASADALRSLVFILLGAALLFWFY
                     TSKDRKKVATFVGIGVAVLMLVDLWTVDKRYLNDSNFIRQKPTEVYKETVADQEIMKDK
                     DLSYRVLNLNNPFLETTTSYYHHSVGGYYAAKLRRYQELIDHRLQGELNSVIEAFQKAQ
                     IAEDLMGAFAACPSLNMLNTRYIIYNPEQPPLRNPFAFGNAWFVDKVEVVENADAEIAA
                     LNTINPLTTAVVDKRFADEVKGFTPQLDSTATITLDSYRPNKLVYTTKTNSEQLAVFSE
                     IYYQPGWEATIDGKPAPHFRADWILRAMLVPAGEHQIVFEFRPQGYITAAYITSFSSLI
                     ILLLLIGAIGYSIWRAKKDKTA"
     CDS             complement(15388..16149)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg24_16"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.6e-30,
                     bitscore: 97.3, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQQPTFSIITITYNAERWLERTILSVLSQSYPNIEYILIDGASK
                     DKTVEIIKQYESGIASWISEPDKGLYDAMNKGLKRATGDYVWFLNAGDTLYTADTVQRI
                     VASLKKKVSLPDVIYGETQIVDAEGRSLGMRRLKAPEKLTWKSFRMGMLVCHQSFISKR
                     EIAPLYNTEYRLTADYDWCIQCLRRSKRIHNTRLTLSNFLEEGLSSVNRKASLKERYEV
                     MCKYYGKVSTILLHGWFAVRFYFAKWFKGRV"
     CDS             complement(16162..18024)
                     /locus_tag="ctg24_17"
                     /transl_table=11
                     /translation="MDDQHKPEWIKVDEWDFVEYVDSLLRSQEAVDLEFKTARAGFPNS
                     VWETYSSFANTDGGTIVLGIKEKNGALFVEGLLPEQIVSYRQIICNQLNNPDCVNVNLL
                     TDKNIQEVDYRGKSLLLIYVPRASRSQRPVYLTRNPLNGHTYKRNNEGDYKCTDTEVRR
                     MIADADEEHPRDSRILCNYSMEDIDLDSLKQYRLLLSSRQPDHPWLTLDDMAFLRKLGG
                     YRQDRQTGQEGFTLAGILMFGRTESITDNECAPSYFPDYQEKMSVDENVRWTDRICMDG
                     TWEANLFQFYRRVYPKLSSVLPKPFRLENGVRLEDTTTHVALREAFVNTLVHCDYMEEG
                     NITIEQWKDRYVFKNPGTLLVSKAQYYAGGESICRNKSLQKMFMLIGFSEKAGSGVNKI
                     FMGWKNANWRPPFVEEQSHPDRVVLNLPMESLYPEEVLEELKRLFGREIERIPYDQFTV
                     LALCYSEKQVSNERLQYILNQHSSNITKLLKSMCNAGFLESIGNGRGTRYRLLFLEKDE
                     SKPQKDESKLKKDESKSQKDESKLEKDESKKYMRYEDLSRLILSVCEDYVALEIIAEAV
                     HREASYLINRVIPRMLEDGLLERLYPSSPKHPLQKYRVRQVGNL"
     CDS             complement(18123..19385)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 121.7;
                     E-value: 6.9e-37)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg24_18"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.3e-25,
                     bitscore: 82.2, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKILILNTSELTGGAAVAANRLAKALGKSGVEVSMLVRDRKTDHV
                     KVFSVNNSWTSHRLNSFRFIWERLIIFICNFFSKKNLFQVSIANTGTDLSKHPLVQQAD
                     VIHLHWVNQGFLSLSDIKKLVNTGKPIVWTMHDLWPATAICHYPGGCEKYISNCYQCPM
                     LKRNPFFDLAASVFKEKGKIGLSKITFVGCSRWIMEEAQKGNWLRTACFTSIPNPIDVT
                     AFKRMEKRVARKRFDLPEGKFLLLFAAAKLSDTRKGAIFLIEACEKLKEKYQDRIEIVL
                     MGNSSEELISQFPFKVNTLGYISDQDSMISVYACADMFVIPSLEDNLPNTIMESMACGT
                     PCVGFETGGIPEMIDHLKNGYVAKYKDTNDLAVGIKWIIDNQETFRFSEACVRKVHDCY
                     RESVIAEKYIALYQSLCNKRK"
     CDS             complement(19382..20713)
                     /locus_tag="ctg24_19"
                     /transl_table=11
                     /translation="MEENQHTEFKESWHDEYTRYISAFCNTEGGVLYIGIDDKGEVVGI
                     EQPKKLIEKLPNFIAQKTGIMPLIHLREKAGKEYLEIEVQPSAMPISVHGRYYTRSGSV
                     TSELQGNQLNMFLAAKMGLTWESVIEEDFSLEDIDTDTVERFKLLAKDRVPSIEQETDL
                     LALMERLNLIVGGRFKRAAVVLFGKNVQRYVLQARIKIGKFLTDTEVLTTDIVEGNLIQ
                     QVDRALDILRTKYLLSYISYEGIHRREKLVYPYEALREALLNSIIHREYFVSSEIQVRV
                     YEDKLVIGNEARLHDITVEDLSRPHPSRPHNKLIADVFYKAGFIESWGRGTQRIIDNCL
                     AEGLSAPVYEHKMGFLYLTFFHERINERINERINERINELSDMEREVYQILREEPTIRQ
                     IDLANRLDLTEQYIRKLIKKLKEHGWIERIGARKNGYWKIIEKS"
ORIGIN
        1 aaaaaagata gtagaatcta ttgcaaatca aaaaggaatg tctacctttg cgaccgctta
       61 gataacatag tattaattta ttaaagtaaa aagaatcatg tatttagatt cagcgaagaa
      121 aaaagaatta tttgaaaagt atggcaaatc agcaactaac acaggttctg ctgagagcca
      181 aatcgcattg ttcacattcc gtatctctca cttgacagag cacttgaaag tgaatcacaa
      241 agattacgct acggaaagat cattgaagat gttggtaggt aaacgtcgtc gtttattgga
      301 ctatctgatc aagactgaca tcgagagata ccgcgctatc atcaaagaac ttggtatcag
      361 aaagtaagaa aaagcttact cgaaaatatt aaaaagggca atcccaaatg ggtattgccc
      421 tttttatttg tcttaatcct agatataata aaatattaat gtaaatttgc gccgtttagt
      481 atcaaattat caaacattac aggactataa ataacaaatc atacacatgg gaaacaacaa
      541 aattataggc gcgaaaatta aaaatatccg ggaatcgaaa caactctcta tcgaggaggt
      601 agccgaacgc tccgggttag gtatcgaaca gatagaacgt atcgagggta acttggattt
      661 tccatctttg gcccctctta tcaaaatagc acgggtatta ggggtacgtt tgggtacatt
      721 cttggatgat caagcggagc taggcccagt cgtatgccgc aaaaaggaca gcgaggccga
      781 tggtatcggg ttcacgaaca acgcgacaca aggacacaag catatggatt accactcgct
      841 ctcacaagat aagtccggcc gccatatgga acccttcttg atcgagatcg ctccctccga
      901 ggaaggcgag gatttcatcc tgtccacgca tgagggagag gagtttatct acgtattgaa
      961 tggcgtcgta gagatcaatt acggaaagaa cacctatatc ctagaggaag gcgatagcat
     1021 ctattatgat tctatcgtgg cgcatcatgt acatgcggca gccgacaaca aggcccgaat
     1081 cctaggagtt gtctatacac cttattaaat ccggcgtttt atggaattac ataacagaac
     1141 ccttggccaa tggctggaac attgggccga gaatacaccg gataaggagt atatcgttta
     1201 ttcagaccgt gacttacgtt tcacttggag cgaattcaac aagcgtgtgg acgacatggc
     1261 gaaaggtatg ttggcgatcg gtatcaccca tggcacacat gtcggcgtat gggcgacgaa
     1321 cgtaccggat tggttgacat tcctatatgc aggcgcgaag atcggtgccg tattggtcac
     1381 gatcaatacg aactataaac aaagcgagct ggaataccta gtagagaacg ccgatatcca
     1441 tacgatgtgt atcacagacg gcgtgtttga tggaagttac gtggacatgg tctataccat
     1501 gttgccggaa ttgaagacct ctcaacgggg gtatttgaaa agcgagcgtt tcccacgctt
     1561 gagaaatgta gtatatatcg gacaggagaa atacaggggt atgtacaata cgcccgagat
     1621 gttgctcctc ggacaaaata tcaaggatga gaccttagag gctgccaaag cgagagtaaa
     1681 ttgccacgac gttgtcaata tgcaatatac ttccggtacg accggcttcc cgaaaggggt
     1741 catgttgact cactacaaca tcgccaacaa cggtttcttg acgggtgagc atatgaaatt
     1801 caccgccgac gataagcttt gttgctgcgt acctctcttt cattgctttg gcgtggtatt
     1861 agcttccatg aacgtattga cgcatggatg tacgcaagtg atggtcgaga aattcgatcc
     1921 gctattggta ttagcttcta tacataaaga gcgttgcacg gccgtgtacg gcgtgcctac
     1981 catgttcatt gccgagctga accacccgat gttcgagatg ttcgacctca cgtcgttacg
     2041 taccggtatt atggcaggtt ctctttgccc ggttgaactc atgaaaaccg tggacgagaa
     2101 gatgcatatg cgtgtaacca gcgtgtatgg attgacagag acctcaccgg gtatgaccca
     2161 ctcccgtatc gaagatccgg ccgaggtgcg ttataatact gtaggccatg agttcgaatt
     2221 taccgaggta cgggttatcg atccggagac tggcgaggaa tgccccgtcg gcgtacaggg
     2281 cgagatgtgt aaccgcggtt ataataacat gaaaggttac tataaaaacg aagccgccac
     2341 caatgaggcg atcgacaagg atggtttcct gcattccggc gacttgggcg ttcgtgatga
     2401 gaatggaaac ttccgtatca ccggccgtat caaggatatg attatccgtg gaggcgagaa
     2461 tatctatcca cgtgagctgg aggaattcct ttatcatttc cccggcgtga aagacgtgca
     2521 agtagccgct gttccttcca agaaatatgg agaggaagtg ggtgccttta tcatccttca
     2581 cgatggtgtg acggctacgg aggaagaggt gaaagatttc tgccgcggaa agatcgcccg
     2641 gcataagatc ccgaaataca tcttcttcgt cgataccttc ccgatgaccg gaagcggaaa
     2701 gatacagaag ttcaagttga aagacctcgg gctgaaacta ttgcaagagc aaggtatcac
     2761 gccggcctga cgatttagtg gacagctaac agttgacagt tactttaaaa tcttcataat
     2821 gggcggtacg atcttctcgt gttgcccatt ttcctaaaga actatggacg gaatcaacac
     2881 gctgcgttac tcggatttat ttttagcgat gtatttcgat ggcgggaaga gctgcctgca
     2941 ccggaatcat tcgcatgtgt tggtgtatgt atattccgga gagatggtaa tcgacgagaa
     3001 aggccaaatc acccggttac ataaaggaga atgcgctttc atccgcaagg acttcagtgt
     3061 gcagatgacg aaacaagcat ggaatggcga gcagttcaag gcgatcttct tgatgttcac
     3121 catgaagttc ctacgcgact tttacagcaa attagatcga aatactctcc ctaaagatgc
     3181 caagcgagat caggtaagcc tttacaagct accgtccaac cgtcccgata tcgtaagctt
     3241 gtttgagtcg atgacccctt atttcaattc caagatccaa ccgacagacg aattgctgca
     3301 actaaaaatg gtcgagggcg tttatgtgtt gctcaatacc gacaagaatc tatatgcctc
     3361 tatcttcgat tttaccgatc catggaagat agacatactg gaattcatgg agcggaatta
     3421 catgaacgat atttccatgg aagaaatcgc caactatacg ggacgcagtc tctccacatt
     3481 taaacgtgat ttcaagaaat gtagcgctct ctcgccccgg gaatggctca tccgacgccg
     3541 ccttgaagcc gcacacgggc tgatacgtaa aggggggcgt aaggtctcgg agatttgttt
     3601 cgaagtaggc ttcaagaacc tttcccattt ctcgaaaatc tataagatag cgtatggcgt
     3661 accgccaacc gaggatatat aatattaatg gcccacacaa caaagctatt tgaaccacat
     3721 aacaaagcct ctataccact ccctccttat cttcgcgaca taaataataa caaaatgtaa
     3781 atcaaatgat catgacaaag acaacggaag agaaagtagc tttagtaacc ggttctgcga
     3841 tgggtatcgg actcgcttgc gccgaagcct tcgccaaggc tggatacata accgtattgg
     3901 cagacatccg tgagccgaga gaacaggtag agaaattagt agccgaggga cataaggccg
     3961 tagcgtatcg gtgcgacgta tcaaacacgc aagccgtaaa ggagatgatc gactggatcg
     4021 tagctaccta cggaagactg gacgcggctc ttaacaacgc aggcatacaa acaccgcaac
     4081 gcccaatggc agaaatcacc gacgatgaat tcgaccgtac cgtggctgtg gatttgaaag
     4141 gtgtctggaa ctgcatgcgt tatgagatcc tgcaaatgct gaaacaaggc ggcggagcca
     4201 tcgtcaacac ctcatcgcaa ggcggagtca cgggatttcc ggggcaagcg gcctacatag
     4261 cctgtaagca tgccgttatc ggactgacac gtaccgccgc tatcgactat gcggcaaaga
     4321 acatccgcat caatgccgta tgtccgggcg ttatccgtac gccgatggcg gaagacttaa
     4381 tgcggcgtga cccttccttg gagaaggagc tggtgcgcga cattcccgca gggcggctcg
     4441 gtaaaccgga agagatcgcc aacgccgtac tttggctatg cagcccgcaa gcgagcttcg
     4501 tcgatggcca cgcgctattg gtagatggag ccttcagtat tcattaaagc gcaaaactac
     4561 agagagccca atactgcatg gctgttgcag aactactgca aggcaggttg cagtaacgaa
     4621 cccacctacc cctcggcaag cctctgccct agatggaaat tcatagataa agaacaccta
     4681 ctatcaacgc tttttcgtac cttcgcgtct caaccattta tagtattaat ttatgtcaca
     4741 attatttcca actaatctgc cttataaagt ggcagatatg agtttggctg aattcggtcg
     4801 caaagagatc gagatcgccg aacacgaaat gccgggatta atggcgctac gccagaaata
     4861 cgccgatcag aaacccttga aaggcgcacg tatcaccggc tcactgcata tgactattca
     4921 gacggcggtg ttaatcgaaa cattagttgc gttgggagcg gacgttcgct gggctagctg
     4981 taacatcttc tccacacagg accatgcggc agccgctatc gcggcggacg gcgtaccggt
     5041 attcgcttgg aaaggcgaga cgctggaaga atattggtgg tgtacggaca tggcgcttcg
     5101 ttttccggaa ggtaaaggcc ctcacatgat tgttgacgat ggcggcgacg cttccttgct
     5161 gattcacatg ggctatcgtg cggagaacga cgcggagacc atcaaccgca aaggcgggaa
     5221 tcatgaggaa caggtaatcc tggatacatt aaatcgcatc cttcaagaag ataacggccg
     5281 ttggcaccgt acggtagccg agatgaaagg tgtgtcggaa gagacgacca ccggcgttca
     5341 ccgtctgtat cagatgatgg agaaaggtga gttgctggtt ccggctatca atgttaatga
     5401 ctccgtgacg aaatccaagt tcgataactt atacggttgc cgtgagtctt tggcggacgg
     5461 catcaaacgg gctacagacg tgatgatcgc cggcaaggta gtagtcgtgg ccggatacgg
     5521 tgacgtaggt aaaggctgct ctcactccat gcgctcttac ggggctcgcg tactcgtgac
     5581 cgagatcgat ccgatctgcg ccctgcaagc cgctatggaa ggtttcgagg ttacgaccat
     5641 ggaagaggcc gtgaaagagg gtaacatctt cgttacaacc accggaaact gcgatatcat
     5701 cacgatcgag catatgacac agatgaaaga tcaagcgatc gtatgtaaca tcggtcactt
     5761 cgacaacgag atccaagtgg acaagcttgt caactatccg aatatcaagc acacgaatat
     5821 caaacctcaa gtggacaaat atacgttccc gaacggaaac tccatcttct tattggcaga
     5881 gggacgcttg gtaaacttag gttgcgctac gggacacccg tcattcgtaa tgagtaactc
     5941 gttcacgaac caagtgcttg cccagatgga cttatggcaa atggcttatg aggtaggtgt
     6001 ataccgctta ccgaaacgct tggatgagga agttgcccgc ctacacttgg aacgtatcgg
     6061 cgtgaaatta tctacattat cacaaaagca agctgattat atcggtgtac cggtagaagg
     6121 accgtacaag gctgatcatt acagatacta attaattgaa gattgaaagt tgagaattga
     6181 taatgaaggg agggcagctc ctgtagttct cgattcttaa ttttcaattt tcaattctta
     6241 attttcaatt accatgcgtt tcgctattct ctcccctatt tatccctatc gtggcggtat
     6301 cgcccaattc agcgggatgc tctatacgga attagtaaaa gaaggtcatg aagtaaaggc
     6361 tttcaacttc aaacgtcttt atccggatat cttatttccc ggcaagactc aatacgtaga
     6421 agcgggagac cgtgcgatcg aaatcgagag cgtgcgagta ttagatagcg tcaacccggt
     6481 tagttatttc agtaccgtaa acgccattcg ttcctatgcg ccggacgtac tgattatctc
     6541 ttactggatg tcctttttcg ttcccggata cgcccacgta gcgaaccgga tgaagaagca
     6601 ttgcaaggta atcaccctta tccacaatgc gattccccat gagccgcgtt tcttcgacaa
     6661 gcctttagct tcgttacttt tcaagcaatg ccatggcttt atcgtgatga gcgataacgt
     6721 gcggtatgat ttgcggaaac tttacccggg cgctaaatat atccagaacc cacacccgct
     6781 ttacaatcat ttcgggagta agatcaacaa gaacgaggcg tgccggaaat taggaatcca
     6841 tccgtccaaa aagaatcttc tattctttgg actgatacgg gattataaag gattagatct
     6901 gctgatagaa gcgatgggac agcttaacga ggattaccat ctcattatag ccggcgaatg
     6961 ttacggtagt ttcgagaagt atcaggctct gatcgatgca tctccggcaa aagaacgtat
     7021 attcgtccac tgtgaatata tcagcgacga ggaaatcccc atttatttct cagcggcgga
     7081 tgccttggta ctcccctatc gctccgccac tcaaagcggt gtcgtatccg tagcctacaa
     7141 ttacgattta cctatgttaa gtactcccgt aggcgatttc aagaacagca tcgaaaagcc
     7201 gggtacaggc atcgtagtgc ctgagatatc cgcaacggcc ctcgcccaag gtatcgagga
     7261 acttttcacc ccctcacagc aagccaccat ccctgcgaac atatccaaag aaaaagcagc
     7321 cctctcgtgg gaaaccctaa cgagaaaact gctcgatttt atcaatagcg gtttcatcta
     7381 ggacttactg actattttcc acttgacatt ctcttcaaac agcacagata gatgcatttt
     7441 atttttttaa cgcaaaaaaa ataaaagaca tacatactta tttctctaaa atcattacat
     7501 tgcgaaatca cgttaaatac aagaatgaga aaacaaatat tgataatatg catctacata
     7561 ggagaattac cttggtattt taaattcttc ctaaaatctt gttccttcaa caaggacatt
     7621 gactttctca tcctttgcga tcaagacatg actagtaaag ggatctctaa caatattaaa
     7681 atcaaaagat atgatctaca agactttaaa aaagatgttc atagatcttt aaacatcaat
     7741 actccaattc aaaatggata caaactatgt gattttaaac cggcatatgg ttacatattt
     7801 tctagatata tagaaggcta tgatttttgg ggatactgtg atattgatgt catttttggg
     7861 aatataagag catttataac agaaaatata ctttctaaat atgaaattat aactgtccgt
     7921 caagattatt tatccgggtg ttttacattg ttcaagaacg aacataaaac aaacacacta
     7981 tttatgcaaa gcaaaaatta tctaaaagtt tttctatctg aaaaaaactt ttgctttgac
     8041 gaaacaaact ttgcttttga tgaatttgca aaatcaaaag atgcatataa tataaataca
     8101 gagatagaaa gcatgactca tgttgtatta aaaatgaaag ataaaggctt attaaagcca
     8161 tacttcaacc ttcatatcct tgaaggacta cctggaaata tgacatggaa gaaaggaacc
     8221 ctattatata aaaacaagta tgaggtttta ttatatcacc taatattctt taaagatttc
     8281 ttcaaacaat ataacaaaag tactgtaccg gatgaattca ttatagagca aacaagaata
     8341 actgagattt ccgcatttag ctattaaaat ctattcatat ggaagatcta tttaaaacat
     8401 acaaaaggaa tgttgcatta ggtattaata tagacaacct atattacata tacgacaggt
     8461 cttctaataa cattttagaa gtcagtaaat atatctatga aaatctagat tatctatcac
     8521 tttttgaaag ttccattgaa aatattttta ttaataaaaa actttcagca aactacttta
     8581 atcaatggat tcctaagctc aacacattaa aacaaaacat agataatacg ttatctgaat
     8641 taacactaaa tattacagaa acgtgcaact tcagatgcaa gtattgtttc tttaacaaaa
     8701 aaaaatagaa gaatcatact ccaaatcaat gtccttaaaa acagcaaaaa aagcagttga
     8761 tttttatttc aaaaacagca ataattgcaa ccaccaaata tcattcatag gaggagagcc
     8821 tctactcaag ttcaacttaa taaaaaaaat tgttgaatac ataaaaacat tcaacaacaa
     8881 agtatcattc acaatcataa caaatggctc tttattaaaa gaagacatat taaattatct
     8941 aattgaaaac atgtttcata taactataag ttttgatgga gaaaaagaaa ttcaaggatt
     9001 gaacagatta tcaaaagata aaaaaaacag ttttgatata gtatataaca atatacgcaa
     9061 aatacaacta aacaacacaa gatacttcga acaatatgta acaataaatt ccgtatattc
     9121 aatcaatata acaagttccc tttccgaatt caccaactat ctagaagcac atttcaaaaa
     9181 taaatttgct ataaatattc aatcatctga gataaacgat gaatacacga aattccataa
     9241 taatttcaca aaatcctttt tatcaatata tgaaaatata cacatacaag gattcgaaaa
     9301 tagctccccc cctttattta taatttccag cgacttacat aaaaagatga tgttcttttc
     9361 aagaagatca aacaacatcc tgcaagaaga aacaagattt attcccataa aaagctgcct
     9421 tccttactta aacaagatat atatatcacc gacaggtgac attttcatgt gcagcgattt
     9481 atattacata aaaggattta atatcggaaa tattgataaa tctatagaat taaacaagct
     9541 acaagatata atgacacaat acactaactt cagaaataaa acatgtaaaa aatgttgggt
     9601 ttatagattc tgcgattttt gtttttatac attatatgct tctaaagaac gaaaaggaat
     9661 aaataaatat tgtaaaataa taaaatatga ttacgcccaa gtcatcaaat catatattaa
     9721 gatattaaaa tcaaacggga gtgcgtttga tatatattac taacatataa aattattcag
     9781 cgtatgaaac aaaaaacgaa gaaaatctca tgggaaaact ttaaagacga gattaaagta
     9841 atctctgccg gacagcaaaa gttactcacc ggaggtggat gtgcttgctg catctgtagc
     9901 ccaggtaatg ggaatagcgg tttaggaggc tcaaccaaag cttcaatttc acattaataa
     9961 cctgcgggga gatttctctc cccgcataag ctttcacttt atggaaaaac tagaatacaa
    10021 aaatagccca gtactaggtt tcattttaaa ttcaaaatat tacctatacg atagatattc
    10081 caattccatt tttacagttc caagaatatt ttttgagtat ttagacgatc taattagcct
    10141 tgacacagat gaattcactc aaaaatatca taatattttt tcaaaagagg agattataga
    10201 tctatttaag acattagatt attgccaaaa cgacaaaaaa ctaataaaac ctaatagaat
    10261 acctaaattc accatttcat ccatctattc taacgctaaa aaagtagaaa agaaactcaa
    10321 aaaagaatta accttcctat gcataaatat aactgaagaa tgtaatctca gatgcgagta
    10381 ctgcatattc tctgggaaat atacgaaatc aagaagacat aacagcaaca atcaaatcga
    10441 gtggaattat atagaaaaag gtgttaattt attcttagaa cacagcacag actctaatat
    10501 tagaaaaata ggtttctatg gaggcgaacc tcttctatat tttgacataa taagaaaaac
    10561 tatcaattat gtccgaagta aatgtgataa cgcaattttc acaattacca caaatgcaac
    10621 tttactaaaa gacaaaattt tgtctttctt tgtagaaaat aatgtagaga tcaccattag
    10681 cctagatggt cctcaaaaca ttcatgataa aaacaggatt tttcctaatg gcgttgggag
    10741 ttttaacacc gtcataaaaa acatagaatc tatcaaacga ttacatcatg atttttttga
    10801 aaataatata aaattctcag cgacattatc acctgggaaa tacaaaatca aagatttaat
    10861 tgactttttt acatacgata tgttccctac gctgaaaaga gcagaccttc cattaagtct
    10921 taattatata aattacgaag aaaataaata tttaagcgaa gtaaaatatt tagattggac
    10981 aaaaaaaact gaaaacgaaa tttttaagtt atataaaaaa atccatataa aaggaatcaa
    11041 taaaacttct gaaataccag cagttctaag agccctacct attcatcgag aaatgatgta
    11101 tatcaattta agaagtaata tagcttttga tgaatttaag ttcttttggc ctaatggagc
    11161 ctgcatacct gggatgagaa gtattttctt gaattctaaa gggatctttt tgccatgcga
    11221 gaaactaaat tcagaaacag agttttgcat aggtgatgta tcaacaggat ttgacataaa
    11281 aaaaatatca caactcatag cagattactc aagagaaata gctccactat gttccaactg
    11341 ctgggcattt aggttttgtg gggaatgctg gacaaccgca gtaaagaatg gacaaatatc
    11401 aaaagatttt agatcgcaat attgcagtta tataaaaagt tattgggcaa gaaggctatt
    11461 tttgtataca gaaataatcg aaaaaaatcc caaagcattc tcttatcaag gaagtataga
    11521 ttatcctgaa tttatgtctc acatgattaa cgaataaact aaaacaacca tgaacaaata
    11581 cattacatat ctattccttt tattattatc ttgcggaaag ccccaagata ataacggtat
    11641 attcacaatg gatctatcca aagatgacct tcccaaaaca acggtatcat tggatgatta
    11701 tacaaccaaa tggacaagga tagatcttga gactactgaa gattgcctac ttgatccatc
    11761 gtttaacatc taccctacag atcattttat tgtcgcttat tcctttaatc gaatcctcgt
    11821 attcgaccat acaggacatt ttatccgcga gatctcccat ttcggagaag gtcccgacga
    11881 acatggtctt ttattcaact gtacagtcaa tcctacgagt gaacaacttg tcttcgtaga
    11941 aatgggaaat accgaagaaa taattcgtta tgatctatcg agtggcaaac aattgactgc
    12001 gataccaatc gtcgcaaaaa agcagttatg tgacttatta tttatcaagg actctacact
    12061 tgtctgcttc ccatacgcag gcaatcaaaa gcaaatggcc tacaaacaaa atctagccgg
    12121 ggaatggatt ggaacacccc ccattcccat ctccgaaccg gcaggtccat ataatcccat
    12181 acctatcagt ctatttcaag tggataatca atggatctat aaagggatct acgaagacac
    12241 gctttactta gtgaataatt tagaaccttt cgctcgtttt tcaaggaaag acatcagtcc
    12301 atcaaaaaca gaattagagg tacagaacag ctcttttata aatcatctgt ttacctctaa
    12361 cggaatgtca ttattcggat acccgcaata tcagttaaaa gaagtatctg aaggcatatt
    12421 cgatttagtt ttagttgatt ttcgagcctt cctttttaat cacgcagaca aacaaattct
    12481 tgaaatagaa aaaatgaact gcccacctct gtcaattatt tatgaacaaa aaaatttaaa
    12541 tgatctattc atgctgatct cctcccggaa cccgaagaaa ttggtactaa aagttccagc
    12601 ggaattcatg ggaaaagaag aagatgaaaa cccagtctta ttcatatccg acttgatata
    12661 tccaaagaaa aagcagccca ctcgtgggaa accctaacga gaaaactgct tggctttatc
    12721 cataacgaat aatcgttacc aatttccacc tagttgtaga gacggggcgt gccccgtctc
    12781 atctcctcaa aatggaaact ttaaaatacc cattagtctg tgccgagacg gggcacgccc
    12841 cgtctctaca actggatatt taggctgtct tgtctttttt agctctccag atcgagtaac
    12901 cgatcgctcc aatcaataac aaaaggatta tcaatgaact aaatgaggtt atataagccg
    12961 ccgtaatata accttgcggt ctaaactcaa atacgatctg atgctctccc gcaggaacta
    13021 acatagccct taatatccaa tccgcccgga aatgaggagc gggcttccca tcaatcgtag
    13081 cctcccatcc cggttgataa tagatctcag agaatactgc taattgctca gaattagtct
    13141 tcgtcgtata aactaactta ttagggcgat aactatccaa tgttatcgta gcggtagagt
    13201 ccaattgagg cgtgaaacct ttcacctcat cagcgaaacg tttatcgaca accgccgtcg
    13261 ttaacggatt aatcgtattc aacgccgcta tttccgcatc cgcattctcc acgacctcca
    13321 ctttatccac aaaccaagcg ttgccgaaag cgaacggatt cctcaaaggc ggttgctccg
    13381 gattatagat aatataacgt gtatttagca tattcaagga cgggcaagca gcgaacgccc
    13441 ccatcaaatc ctccgcgatc tgcgctttct ggaaagcctc gataaccgag ttaagctctc
    13501 cttgcagacg gtggtcgatc agttcttggt accgtctcag cttcgcggca taataaccac
    13561 caacggaatg gtgatagtac gaggtcgttg tctccaagaa aggattattc aaattcaaga
    13621 cacgataaga aaggtcctta tccttcatga tttcttgatc ggctaccgtc tctttatata
    13681 cctctgtagg tttctggcgg ataaagttac tatcgttcaa ataccgttta tccaccgtcc
    13741 ataagtcaac caacatcaag accgcaacac cgatccctac gaatgtcgcc acctttttcc
    13801 gatctttcga ggtatagaac cagaacaaca aagccgcccc taataagata aagaccaaag
    13861 agcgcaacgc atccgccgaa gccaaggaag cacgatccat taacaaggcg ttgtaatacc
    13921 aatctggcaa ctgatattga gcgtcgaaag aagaacggaa atccaacagc atactcggca
    13981 tcaaccaaag gattaaagaa atgccccccg tgatagccaa agcagcgatc aatcctttct
    14041 tcaacaaggc atcgctcacg gtctcggata acacctcttt caatccccat atagcgataa
    14101 taggaaatac catacccgga ataaccaatg ccatctctac ggtacggaac ttattataca
    14161 tcggcaagta atggaacata aagtcattga agctatcaaa attacgtccc aatgccagca
    14221 atatcaaaaa gacagaacct ccgaataacc accatttcat cggattccgg atcacgaaca
    14281 ttcccagaac aaacaagaag cagaccaatg ccccgaaata aaccggcccg gaagtaaatg
    14341 tcttctctcc ccaataggta ggagcctgta cctcttttcc gacttgagcg cctttcgccc
    14401 ttaattcctt atatagctca gaatccgggc ctagcattcc acctgaactt ccaccatagg
    14461 cattcgggac caacaaggtc aacaactccc cttttccata gctccaagcg aacgcataat
    14521 ccttgtctaa gccggaagaa atcttctcgc ccgaaggggt cgttgtcgtt aattccgtag
    14581 ccccacggat agagttctgt cccaaatccc attgagcata catattctgg gcattcggca
    14641 acaccgccaa tatcacgcat ccagccataa tagcggttac cgtacccagt tctttataag
    14701 ctttttcctt cagtttattg aacaaatatc ccaaataaac gaagaagcaa agtaataata
    14761 aataataagt gatttgcagg tgcgtattcg cgatagagaa tgcgacaccc aacaagaaca
    14821 cgaccgcccc ccataaatac ttacgcttga acaacagggc catacccgcc aacgttaatg
    14881 gcatataagc gattacatac gctttcgtga catggccggc ctctataatg atcagattat
    14941 aagatgctaa agcgaaagcg atagcaccag cgatcgccaa ccaccaattt acgcccatga
    15001 cacacatcaa gatatagaaa caaacgaatc cggtaaacac catccccgca tccatatacc
    15061 ccagcgcttt taaaggcttc tccactaaaa gatatccggg aaatcgtgga gccggatttc
    15121 catatcccga cacataaggc attccgccaa acatagcatc agaccatgcg ctgaattctc
    15181 ccggttgggc cgtcttctca tattcatcca tctggctatt ccccataccg atagcctttt
    15241 ccgtatcccc ttgccggact accttaccct caaatacggc cggagaaaaa taaatcaccg
    15301 tcaataccaa gaatacggct atcgctgcga tatgttttcc ccatttactc attatactcc
    15361 gcataaaact tatctataat ttattgttta tactctacct ttaaaccatt tggcaaaata
    15421 gaatctcacg gcgaaccaac catgcaacag aatcgtcgac accttgccat aatacttaca
    15481 catgacctca tatcgctcct ttaaggaagc tttccggttc acactactta atccttcctc
    15541 taaaaaatta gacagggtca aacgtgtatt atgtattctt ttcgatcgtc tcagacattg
    15601 gatacaccaa tcataatccg ccgtcaaacg gtattccgta ttatataacg gagcgatctc
    15661 ccgttttgat ataaacgact ggtgacaaac caacattccc atccggaaac ttttccaagt
    15721 cagtttctcc ggtgctttca atctgcgcat ccctaatgat ctaccctccg catcaacgat
    15781 ctgggtctct ccgtaaatca cgtctggcaa agatactttc tttttcaaag acgccacaat
    15841 tctttgcacg gtatctgcgg tataaagtgt atcccccgca ttcaggaacc acacataatc
    15901 ccccgtagcc cgcttcaatc ccttattcat agcatcatac aagcctttat caggctcgct
    15961 tatccaagaa gcgataccgg actcatattg cttgatgatc tctacggtct tatccttcga
    16021 cgctccgtca atcaatatat actcgatatt cggatacgac tggctaagta cgctcaatat
    16081 cgtacgctcc aaccatcgct ccgcattata ggtgatcgtt atgatcgaaa atgtaggttg
    16141 ctgattcatt tccattatct cttataaatt tccgacttgt ctcacacgat atttttgtaa
    16201 aggatgctta ggagaagacg gatataatct ctctagtagc ccatcctcta acattcttgg
    16261 tataacccga ttaattaaat aagaagcctc tctatgaaca gcttccgcta ttatttccag
    16321 agctacataa tcctcacaaa cagatagtat taacctcgac aaatcctcat aacgcatata
    16381 tttcttactt tcatccttct ccagtttgct ttcatctttt tgagacttgc tttcatcctt
    16441 cttcagtttg ctttcatcct tttgaggctt gctttcatcc ttctccaaaa acagcaaacg
    16501 gtacctagtt ccccggccat ttcctataga ctccaaaaaa ccagcattgc acatactttt
    16561 tagtagcttt gtaatatttg agctatgttg gttcaaaata tattgaagtc tttcattaga
    16621 tacttgtttt tcagagtaac aaagagccaa aaccgtgaat tgatcatatg gaattctttc
    16681 aatttcccgt ccaaacagac gcttaagttc ttctaagact tcctctggat acaaactttc
    16741 catcggtaaa ttcaacacca cccgatccgg gtgactttgc tcctccacaa atggaggtct
    16801 ccaattcgca tttttccaac ccataaaaat cttattcacc ccacttcctg ctttctcaga
    16861 gaagccaatc agcataaaca tcttttgcaa gctcttatta cggcatatac tttcacctcc
    16921 ggcataatac tgggccttac tcactagcag tgttccggga tttttaaata cataacgatc
    16981 tttccattgt tctatcgtta tatttccttc ctccatataa tcacaatgca ccaatgtatt
    17041 tacaaatgcc tcacgtaaag cgacatgcgt ggtagtatct tccaatctca caccattctc
    17101 caaacggaat ggcttaggca gtacagatga taatttagga tacacacgcc gataaaattg
    17161 aaaaagattc gcttcccaag ttccatccat acaaatgcga tctgtccatc taacattctc
    17221 atctaccgac attttttcct gataatccgg aaaataagat ggagcacatt cattatccgt
    17281 tatactttct gtccttccaa acattaatat acccgctaaa gtaaaccctt cttgacctgt
    17341 ttgcctatct tgtcgatatc ctcccaattt tctcaaaaaa gccatatcat caagtgtcaa
    17401 ccaagggtga tctggctgac gactagaaag tagcagtcga tattgtttaa gtgagtccaa
    17461 atcaatatct tccattgaat aattacataa aatacgagaa tctctcggat gttcctcatc
    17521 cgcatcggca atcattctgc gaacttccgt atccgtacat ttataatctc cctcattatt
    17581 tcgtttataa gtatgtccat tcaagggatt tcttgttaaa tatacaggac gttgtgaacg
    17641 agatgctctc ggaacataaa tcagcaaaag agattttcct ctatagtcta cctcttgaat
    17701 attcttgtca gtaagtaaat taacattaac gcaatccgga ttattcaatt ggttacaaat
    17761 gatttgccga taagacacaa tttgctctgg aagaagtccc tccacaaata gtgccccatt
    17821 tttctccttt attcccagaa cgatagttcc tccatctgta ttcgcaaatg aagaatacgt
    17881 ttcccacaca ctatttggga atccggcacg agcggtctta aactctaaat cgacagcctc
    17941 ttgactacgc aacaagctat ccacatattc tacaaaatcc cactcgtcca ccttaatcca
    18001 ttcaggctta tgctgatcgt ccatttattc catttttcca caaatgtagc aattttcatt
    18061 tgctttcaat cacttaccag caagcattca ttcttacttc gatatgctga tcttctttca
    18121 cgctattttc tcttattaca caggctctga tacaaagcta tatatttttc ggcaataacc
    18181 gattccctat agcaatcatg caccttgcgg acgcaagcct cactaaatcg aaaagtctct
    18241 tggttgtcaa ttatccactt aatccctaca gccaaatcat ttgtatcctt atatttagct
    18301 acatacccat tcttcaaatg atctatcatc tccggaatcc ctcctgtctc aaatcccaca
    18361 caaggcgtac cgcatgccat cgactccata atcgtattgg gtaagttatc ctccaacgaa
    18421 ggaataacga acatatcggc acaggcataa acggaaatca tagagtcttg atccgatata
    18481 tatcccagcg tattcacctt aaaaggaaac tggctaatca attcttccga gctatttccc
    18541 atcaacacga tttctatgcg atcttggtat ttctctttta gtttttcgca agcctcgatc
    18601 aaaaaaatcg ctcctttccg ggtatctgaa agcttagcgg cggcaaaaag aagaaggaac
    18661 ttaccttccg gcaggtcgaa tcgtttacgg gccacccgct tttccatacg cttaaaggct
    18721 gtcacgtcaa tcgggttagg aatcgaggta aaacaggctg ttctcaacca attgcctttt
    18781 tgggcctctt ccattatcca tcggctacaa ccgacaaatg taatcttaga taaccctatt
    18841 ttccctttct ccttaaaaac agaagccgct aaatcaaaaa acggatttcg tttcagcatc
    18901 gggcactgat aacaattcga tatatacttc tcacatcctc ccggataatg acaaatagcc
    18961 gtagctggcc acaaatcatg catagtccac acaataggtt ttccggtatt tactaatttc
    19021 ttaatatcag aaagagacaa aaatccttga ttcacccaat gcagatgaat cacatccgcc
    19081 tgttgcacta atgggtgctt cgataaatcc gtgcctgtat tggctatgga aacttgaaag
    19141 aggttcttct tgctaaagaa gttacagata aagattatca gtcgttccca aatgaagcga
    19201 aaagaattaa gcctatgtga agtccatgaa ttatttacag agaaaacttt tacatggtct
    19261 gttttccgat cacgtactaa catagaaacc tctacaccag atttacccaa tgctttcgct
    19321 agtcggtttg cggcgactgc cgctccaccg gttaattcag aggtatttaa tatcaatatc
    19381 ttcatgactt ctctattatt ttccaataac catttttcct agctccaatg cgttcaatcc
    19441 aaccatgctc tttcaacttt tttataagct tccggatata ctgctctgtc aaatccaaac
    19501 gatttgctaa atctatttga cggatagtag gctcctctcg caagatctga tatacctccc
    19561 gttccatatc cgacaattca tttatccgct catttatccg ctcatttatc cgctcattta
    19621 tccgctcatg aaaaaaagtc aagtataaaa aacccatctt atgctcatat acaggagcgg
    19681 ataatccttc tgccaagcag ttgtcaataa tacgttgtgt tccccgtccc caactctcga
    19741 taaagccagc tttgtaaaaa acatccgcta tcaacttatt atgaggtcta gaggggtgag
    19801 gacgagacaa gtcctcaacc gtaatatcgt gcaaacgagc ttcattccct atcaccagct
    19861 tgtcctcgta aacacgtacc tgaatttcgg aagaaacaaa atattctcga tggataatcg
    19921 aattcaataa ggcttcccgc agagcctcgt agggataaac cagtttctca cgcctatgaa
    19981 tcccctcata cgatatataa cttaataaat atttcgttcg caatatatcc aaagcccgat
    20041 caacctgctg aatcaggttc ccctcgacaa tatcggttgt cagtacctcc gtatcggtaa
    20101 ggaactttcc tattttaata cgagcttgta acacatatct ctgcacattc tttccaaaca
    20161 agactacagc ggctctcttg aaacggcctc ctacgatcaa attcaaccgc tccatcaaag
    20221 ccagcagatc cgtttcctgc tcgatggaag gaacccggtc tttagccaat agcttaaaac
    20281 gttctaccgt atcggtatct atgtcctcca atgagaaatc ctcctcgatc acactttccc
    20341 atgtcaaacc cattttcgca gccaaaaaca tatttagctg attcccttgt agctcggaag
    20401 taacgcttcc actccgggta taataccgtc catgcacgga aatcggcatg gcagaaggtt
    20461 ggacttctat ttccaaatat tctttaccgg ccttctccct caaatggata agaggcataa
    20521 tacccgtttt ctgagcgata aagttcggca gtttctcaat caacttcttt ggctgctcta
    20581 tccctacaac ttctccttta tcatcgatac cgatatataa tacaccaccc tccgtattac
    20641 agaaagctga tatataacgg gtatattcgt catgccatga ctctttgaat tcggtatgtt
    20701 ggttttcttc cataatctaa aattatatca aacttttttt ctaaatatcc tccgaacaca
    20761 agtatttaat ttaactaaca aggaatatgg taaacaattt aaaaacaaat gatagttaca
    20821 atccaaattc aataatcccc aaggcaataa acgtatatac tccaaaaatg cacttttctt
    20881 atcattatca aaaacaaaga ttacaaatct tatcttgtac caaagataaa cataattatc
    20941 taagtctttt atctgataag agcagtttag cctccaaagc tctataccaa catagtcttc
    21001 ttttattgct ggctgcatat ttttcttaac actcaaatag caactgctat ctcttctata
    21061 caatgctagg tttgatttcg aataagctat tttatacaag caagctaatt tagcccaaac
    21121 gattacatct tcacctaaag aaatgccctc agggaaacaa ccaatagata aaatagcctt
    21181 ttttcgaaca gccacagctg aagtccaaat aggtcctctc gcttttgagg ccatcgtaaa
    21241 ataattatct aaaataccct cattctcttt aaaagaataa taatcaattg atgcgggagt
    21301 tatcatatta ttcatcttaa atgaataagc tgtaccaaaa atatcacatt ccggatattt
    21361 ttcaaccaag aaagcgatag tttttaaata atcaggtaac cactcgtcat cagcatcaag
    21421 aaaggcaata atctcacctc tagcttcttt aataccttgg ttcctcgctg cagaaacacc
    21481 tttgttctcc tgttcaatca atcgaactga atttttaaac acagcttcat tttctgaaag
    21541 aaaatccatc aaaacag
//
