LOCUS       c00016_gnlPro..        14504 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KGBLIONN_16.
ACCESSION   c00016_gnlPro..
VERSION     c00016_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 07:27:58
            Original ID  :: gnl|Prokka|KGBLIONN_16
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 50428
            Orig. end    :: 64932
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14504
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[60428:64844]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14416
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
     cand_cluster    1..14504
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /kind="single"
                     /product="Glycine_cleavage"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14504
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Glycine_cleavage"
                     /region_number="1"
                     /rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T, GDC-P,
                     SoxG]) and GCV_H and GCV_T_C)"
                     /tool="gutsmash"
     CDS             complement(251..1018)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_53"
                     /sec_met_domain="HAD (E-value: 5.5e-36, bitscore: 116.8,
                     seeds: 107, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDDWKKRGAALFDMDGTLLPWDTQYVFSCFVVRRHPWRRLLIFL
                     FLACIPLYILRIWDENRMKRAYLMYLWGLPAETVREYGRKFAEMAQEWIYPELKERLAG
                     YRKKGYLCLMVSASPSFYVKPLGELLGFDEVLGTDVLLEERMPAMPELPNGNNKGAVKV
                     ERLRERNVLPEHGVLENAVAYSDSAADLPMLLSCRRRVLVNPSPALKEDRLLDGAECLY
                     PARPWKGRFGKIWRIGFFVMGLVNVNNVKSMIC"
     CDS             complement(1149..1760)
                     /locus_tag="ctg16_54"
                     /transl_table=11
                     /translation="MARYTGPRDKVSRRFGVALFGSTKALEKRPFPPGQHGMRAGRKKK
                     SDYGVMLAEKQKLRFQYGVLEGQFRKYYAEAARRRGITGDILLQLLELRLDNVVYRLGF
                     SNTRAGARQLVSHGHITVNGKKTNIASYSCRPGDVIAVGGKASSQQLVTRFLDLTQATV
                     VPDWLECDRDKLTGKIARVPSKEEIAPIVNEQLIVEFYSR"
     CDS             complement(1796..2347)
                     /locus_tag="ctg16_55"
                     /transl_table=11
                     /translation="MASEEITNETAEQPVEAAASAPVAETPAAAVSAPEEIKKPEPRKD
                     IFAELGLGGDDDKPKILKAKGSKNVSTGVVHVSSTFNNTVVTVTDQRGNVIGWSSAGKM
                     GFKGSRKSTAYAGQVVCQDACRQAMGHGLREVEVRVKGPGSGRESAVRAVQTIGIEITS
                     IKDVTPIPHNGCRPPKARRV"
     CDS             complement(2381..2758)
                     /locus_tag="ctg16_56"
                     /transl_table=11
                     /translation="MARLFGTEIPNEKRIEASLPYIYGIGRSTSKRILEQAGINPDIRT
                     GQLTDEQLTKIVQVITTDGILIEGDLRREKQSILKRLTSINCYRGQRHRRGLPVRGQRT
                     RTNARTRKGKKKTVGAQAKKK"
     CDS             complement(2877..3779)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_16"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:4Fe-4S dicluster domain (Score: 66.9; E-value:
                     7.9e-21)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_57"
                     /sec_met_domain="Fer4_16 (E-value: 8.2e-21, bitscore: 66.9,
                     seeds: 227, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARSPERRTDPAEVLPGCRSVICLSYDYDSPGRRPEGEGSICLYA
                     HGKDYHGILEEKLADLQELLSIYGGKQRGYVDSGPVMERDHAEACGLGWRGKSGLIVRR
                     KGGSRFFIATLLTTLELEPDAPVSNGCGSCRRCAALCPTGAIMENGQVDAGRCLSYWTI
                     EHRGAIPEEIRPLIGTRLYGCDTCVTVCPWNGKPLPDVDERFRMSRLLASIPLRGLLSL
                     DAGGFAALFRNSPLKRLKREGLLRNGCVVLGNAGTPDDIDFLKALYGESPLVEEHASWA
                     VERILRRHGRHASSSGARD"
     CDS             3834..4964
                     /locus_tag="ctg16_58"
                     /transl_table=11
                     /translation="MRAFFRTGHPAAGKTKLPGHGAQGIFNNRGIRSQHAGIMNKSMPP
                     TKNFLLSGGNWIACTPPPLHNAAYMNIRILSDGKQGHLNQSLGLAQALISKAGGTVETV
                     DLQGLSLLGKIRKVVTGSDIPRPDLFISAGHATHIPLICARHHFKTRAVLCMKPTLPCS
                     FFDLCLIPRHDLDSGRDYTDTDIFPTQGALHPMRPDPSVPKDTTLILIGGPSKDFDWDD
                     ESMLNQLASISIHTPGHLVLTTSRRTPDGFAEKIRTAVPELTVVPVEETRPGWVARHLA
                     HASAAWVSQDSVSMVYEALGSGAPVGILSVPRRHGSRKSRILSGLETLEKEGMVTGYSD
                     WKKQNFRLTAPGSPLLEADRAADYILSRFFPQLRAL"
     CDS             4988..6073
                     /locus_tag="ctg16_59"
                     /transl_table=11
                     /translation="MESGGVEQVVMELGSGLSSRGVENIVVSGGGRLVPRLEKEGSRHI
                     LMPIGKKSISTLFRIGALRALLQAVRPDILHLHSRVPAWAGYLAWKKLPPEDRPGLVTS
                     VHGFYSVNRYSAIMSRGERVIAVSNCIRDYILDHYPSTPPDHIRIIPNAISPDQYHPAY
                     SPSREWLTGWFMSYPELKGKFTLCLPGRITRLKGHLDLIPVVRQLLEQGIPAHAVIVGE
                     AKKGKEEYKNEVLRAIERSGVSQSFTWTGHRQDLREILSTCSVTLSLTKSPEAFGKSTL
                     EALALGKPVAGYAHGGVKEQLDAFLPEGNVAVGDTAAMADLLARWHAQPPPLPRQIPSP
                     YNMQDMIQAHLDVYQELTPYS"
     CDS             6070..7197
                     /locus_tag="ctg16_60"
                     /transl_table=11
                     /translation="MTPREAAIALNLIPGLGPVRIMRLLQVFASPELILESPSSLLMEI
                     PGVGAQLACRISSWRSIVNPYRELELADNAGAAVTTVFDDSYPSSLRALPDPPIVLYSW
                     GNWTGTDAERSIAVVGSRMATHYGRLCARNISHDLAEAGVTVISGLARGVDTEAHTGAM
                     DAEGRTIAVIGAGLNKLYPRENRNLAQRIADGHGAVVSEFPMDLPPSRTTFPMRNRIVS
                     GWSRATLVVEASGRSGALITARTAAEQGRDVFCIPGPVDRHSSDGCHALIRDGAILATG
                     ASDILQDMNWAVPEQGLPLFSPCPPAGASTPPLPTLEEKEILHAIRLGFNTIDTLCTSL
                     GKTAHTITPLLAKMQIAGQITPDAGGYFSINGREL"
     CDS             7759..8682
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S11"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg16_61"
                     /sec_met_domain="Peptidase_S11 (E-value: 7.1e-56, bitscore:
                     181.3, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLFALLAGFSLCLSSTSCQSYGDSSDYIPLATPVPPQLSQPVSH
                     ALPRPANFPTRPVAIPSSAPRTPRCASACVMDALTGKVLFSHNGLQHRQVASTQKLVTA
                     MVVMEHGSLDKKVVIQPSDTKADPTKLGFRAGEVYSRRELLNAMMIRSFNDVALALARD
                     TAGSVPRFAQLMNAKARQMGMYNSRFANPNGLPADQYSTAIDMARCAYYVYRNPELRNI
                     ICKRQYAFTRANGRTLLLRNTNKLLTQNPWVTGMKTGYTNAAGRCLVSSAGVNGRHVIV
                     VVLGCHPSRIWTESENLIRWALGSAA"
     CDS             8741..9862
                     /locus_tag="ctg16_62"
                     /transl_table=11
                     /translation="MLQAGIVGLPNVGKSTLFNAVTRTRKAQAANYPFCTIDPNVGMVT
                     VPDPRLQVLSDMSGSEKIIPTLIEFVDIAGLVKGASEGAGLGNQFLANIREVDAIVQVV
                     RCFDNDDIIHELGSVDPLRDIDIINSELILADIATMEKRLSSRERKARSGDKEAKAEVA
                     LITKLLPHLNEGNPALTLEPQLDDDERKLLHSFQLLSDKKSIFACNVNEDELADAISNP
                     DAHPYVSQVKKYVAEHHNAEAIVISARIEEELIDVSEEESREFLESLGVKDSGVSDLIR
                     AVYHLLGLRTYLTTGIKETRAWTIPAGAKAPQAAGVIHTDFERGFIAAEVVHYDDLVSC
                     GGKAGAREHGKLRIEGKEYVVKDGDVIEFRFNV"
     CDS             10001..11023
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_63"
                     /sec_met_domain="GCV_T (E-value: 2.3e-83, bitscore: 271.5,
                     seeds: 72, tool: rule-based-clusters)"
                     /sec_met_domain="GCV_T_C (E-value: 2e-23, bitscore: 74.3,
                     seeds: 348, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVPFAGWNMPVQYTGILDEHKAVRETCGIFDISHMGQFTVAGGSA
                     AAWLNSMLTNDINKLNVGQGQYSVMLNDRAGVIDDLILYRMEPETFFVVVNASKIDEDF
                     AWLSAHQPAGVTLENHSDEYVGLAVQGPECGEVFSRVIPGVELPPRNGISRITAEGTDL
                     IICRTGYTGEDGFEFFCPAKEGVKWFEAFLGAGAKPCGLGARDSLRLEMCYPLNGSDLS
                     PDKTPLEAGLGFFCALDTDFIGSDILREQKANGLSRRLAAIEYTGKGAPPRAHYAVHVP
                     GGEAIGELTSGVLSPSLMKGIALAYLPAAYAKVGTELEIDVRGRKFPAVVVKKPFYKKG
                     "
     CDS             11094..11474
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_H"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_64"
                     /sec_met_domain="GCV_H (E-value: 1.1e-47, bitscore: 153.0,
                     seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDVPENLLYSKDHEWIEIDGDIGTIGISDHAQAELSDVVFVDLP
                     EVGATVAAGDPVAVVESVKAASDVYTPVSGEILEVNEELSNDPSLINSDPYGAGWLYKI
                     RLDVPTETEDMMNATDYEEYCS"
     CDS             11570..14416
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GDC-P"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Beta_elim_lyase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg16_65"
                     /sec_met_domain="Beta_elim_lyase (E-value: 1.1e-09,
                     bitscore: 30.0, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="GDC-P (E-value: 4.9e-179, bitscore: 587.6,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTHSDFASRHIGPQGEERREMLDSLGYRTLDELIADIVPADIRM
                     KAPLDLPAAKSETEALEELRSILRKNKLLKTFIGQGYYGTITPSVILRNVLENPGWYTA
                     YTPYQPEIAQGRLEMLMNFQTMVSSLTGLPVANASLLDEGTAAAEAVTMCRNARPKANT
                     FFVADTCHPQTISVIRTRAAFQGVNIIVGDCSSFDPASIGADLAGVLVQYPDTLGRICD
                     YTDFFSRVHATGALCVVAADLMALTIIREPGAFGADICIGNTQRFGIPMGFGGPHAAYM
                     SCTDALKRRMPGRLIGMSIDTLGRPAYRLALQTREQHIRRDKATSNICTAQVLLAVLAA
                     FYAVYHGQEGLKRIGTEIHLKTKSLYKALTEAGIAIENKNFFDTLLLSVPGQADAMVQK
                     ALEAGYNIRRVDADHAAISLDETATCADIAALASALAGAETSATCDCDAPAWDPVHTRQ
                     TPFCTEKAFNSYHSETEMMRYIRRLESRDLALNEAMIPLGSCTMKLNAASEMIPITWPE
                     ANSLHPFVPADQSEGIREMLSVLSDRLAKITGFAAVSLQPNAGAAGEYAGLLAIRRYQK
                     HAGEGHRNVCLIPTSAHGTNPASSAMAGLKVVPVKCDERGNIDMVDLKSQAEAHKDNLS
                     CIMVTYPSTHGVYEQTIKELCDIVHANGGQVYMDGANMNAQVGLTCPGCIGADVCHLNL
                     HKTFAMPHGGGGPGIGPIGVAEHLVPFLPGHLTLGHEEGAVASAAWGSASIAAICWMYL
                     SMMGPDGLREATEMAILNANYIAKKLGHLFPVLYSGNKGLVAHECILDPRQLTHDAGLT
                     VDDIAKRLMDYGFHGPTMSFPVPGTLMVEPTESEPKKELDRFIEAMERIHAEITAIING
                     TADKEDNVLKNSPHTAEMVSADEWRHPYSRSEAAYPVSGLLIHKFWPYVGRVDNVYGDR
                     NLVCTCDTVEEFSKAVEL"
ORIGIN
        1 ctggaagtcg ccacaggagc gggaaccgga gtcggagcaa caatcttgac gggagtaccc
       61 gcaagagcag ctccggcaaa ggatgccaca actgccgcaa cactgatgat gttcttggtt
      121 tgcatgacta ttacttggtt agggtattaa ttgttgattt gctaacatgg aaagaaaaat
      181 gctttttccc cccttgttaa gaaaagtgaa acattttcgt cacaaaagta aagaattttc
      241 tcttgataaa tcagcaaatc attgatttca cattatttac attcaccagt cccatgacaa
      301 aaaatccaat tctccatatc ttgccaaacc ttcccttcca aggcctggcc ggatacagac
      361 actccgcacc atccagaagc ctgtcttctt tcagggcagg agaaggattc accagaaccc
      421 tccgcctgca ggaaagcagc atgggcagat ccgcggcact gtcgctgtaa gcaacggcgt
      481 tttccagaac accatgttcc ggcagtacat tccgctcccg cagacgctcc accttcaccg
      541 cccccttatt attaccgttc ggcagttccg gcattgccgg catgcgttcc tccagaagca
      601 catccgttcc cagaacttcg tcaaatccca gcagttcgcc cagaggcttc acgtaaaatg
      661 atggagaagc ggaaaccatg agacacaaat aacccttctt ccgataccct gccagccgct
      721 ccttcagctc cggataaatc cattcctgcg ccatctcggc aaacttccgt ccatattccc
      781 gcaccgtttc agcgggaagc ccccacaaat acatgagata agccctcttc atccggttct
      841 catcccatat tctcaaaata tagagcggga tacaggccag gaaaagaaaa atcagcaagc
      901 gcctccaagg gtggcgcctc accacaaaac aggaaaaaac atattgcgta tcccagggaa
      961 ggagcgtgcc gtccatatcg aaaagcgctg cgcctctttt tttccaatcg tccgtcatgc
     1021 tttcatccta tacccgcttc ccttaactct caacacccaa ctcttccatg cccctccccc
     1081 tgaatgccca aaaccccggt cgccgaaagg caaccggggt tttgaagcaa atccagaagg
     1141 aaataagatt aacgggagta gaattccacg atgagctgct cgttgacgat gggagcaatc
     1201 tcttccttgg aaggcacgcg ggcaatcttg cccgtgagct tgtcacggtc gcattccagc
     1261 cagtcaggaa ccacagtagc ctgagtcagg tcaaggaaac gggtaaccag ctgctgggaa
     1321 gaagccttgc cgcctacggc aatgacgtcg cccggacggc aggagtagga cgcgatattc
     1381 gtcttcttgc cgttcacggt gatgtgaccg tgggaaacaa gctgacgggc gccggcacgg
     1441 gtattgctga agccgaggcg gtacacaaca ttgtccagac gaagctcaag gagctgaagc
     1501 agaatatcgc cggtaatgcc gcggcggcgg gcggcttctg cataatactt gcggaactgg
     1561 ccttcaagca caccgtactg gaaacgcagt ttttgttttt cagcaagcat cacgccatag
     1621 tcggatttct tcttgcggcc ggcgcgcatg ccatgctggc cgggagggaa ggggcgcttt
     1681 tcaagagcct tggtggaacc gaaaagggca acgccaaaac ggcgggacac tttatcgcgg
     1741 ggaccggtat aacgagccat gatatattag atctatatag gtaaaagatt ctcaattaga
     1801 cgcggcgggc cttcggagga cggcagccgt tgtgggggat gggggtcacg tccttgatgg
     1861 aggtgatttc aataccgatc gtctgcacgg cacgtacggc ggattcacga ccggaaccgg
     1921 gcccctttac gcgcacttcc acttcacgca agccgtgacc catggcttgg cggcaggcgt
     1981 cctggcacac cacctgcccg gcataggccg tgctcttgcg ggaaccctta aagcccatct
     2041 tgccggcgga ggaccagccg atgacattgc cgcgctggtc agtcacagtt acgacggtgt
     2101 tattgaacgt ggaggaaacg tgaaccacgc ccgtggaaac gtttttgctg cccttggcct
     2161 tcaggatttt gggcttgtca tcatcgccgc ccagaccaag ttccgcaaag atatccttgc
     2221 ggggttcggg cttcttgatt tcttcaggag cggaaacagc ggcggccgga gtttcagcga
     2281 cgggagcgga agctgccgct tccacaggct gttcggcggt ttcgttggtg atttcttcgc
     2341 tagccatagt aaagctatat taaaaattca ggttggcgga ttacttcttc ttggcctgcg
     2401 cgccaacggt cttcttcttg cctttacggg tgcgggcatt cgtgcgggta cgctgaccgc
     2461 gtaccggaag gccgcggcgg tggcgctgac cacgatagca gttgatggag gtcagacgct
     2521 tgagaatgga ttgcttttca cgacgaaggt caccttcaat caaaatgccg tcggtggtga
     2581 ttacttgaac aatcttcgtg agctgttcgt cggtaagctg tcccgtgcgg atgtcgggat
     2641 tgatgcctgc ttgttccagg attctcttag aagtcgagcg accaattccg taaatatacg
     2701 gaagggaagc ctcgatgcgc ttctcgttgg gtatttctgt accgaaaagg cgtgccataa
     2761 tggattggat ttgctagctg ttatttttct ctgcctcgcg cagagctatt gcttggggca
     2821 agatggatac cataaattga ggttttgaca agaccaaaac atcatttttt ctatttttaa
     2881 tctcttgcac cgcttgaaga tgcatgccgc ccgtggcggc ggaggatgcg ctccacagcc
     2941 caggaagcgt gttcctccac cagaggagac tccccgtaaa gcgccttcag aaaatcaatg
     3001 tcatccggag tccccgcatt ccccagcaca acgcagccgt tacgcagcag cccttccctc
     3061 ttgagccttt tcaacgggga attccggaac agggccgcaa aaccgccggc atccagggaa
     3121 agaagaccac gcaggggaat ggaagccagc agacgggaca tgcggaaccg ttcgtcaacg
     3181 tccggcaaag gcttaccatt ccagggacag accgtcacgc aggtatcgca cccgtacagg
     3241 cgcgtgccta tcaggggacg gatttcttcc ggaatagccc cccggtgttc aatcgtccag
     3301 taggaaaggc agcgtccggc atcaacctga ccgttttcca taattgcgcc cgtcggacac
     3361 agggccgcac aacggcggca actgccgcat ccgtttgaaa ccggagcgtc cggttccagt
     3421 tccagcgtag tcagcagggt agcgataaaa aagcgagagc cccctttcct gcgcacgatc
     3481 aaaccgcttt tcccgcgcca gcccaggccg caggcctccg catggtcccg ttccataaca
     3541 gggccggagt ccacataccc cctctgcttc ccgccgtaaa tggaaagcag ctcctgcaaa
     3601 tccgccagtt tttcctccag aattccgtgg taatcctttc catgggcgta aaggcaaatg
     3661 ctaccctccc cctccgggcg cctaccgggg ctgtcataat cataggacag gcaaatgacg
     3721 gaacggcatc cgggaagcac ttccgcagga tccgtgcgcc gctccgggga acgcgccatc
     3781 cactccatcc cggcgtgcca tccgcgctcc agccattgaa acaatttttc cgcatgcggg
     3841 cttttttccg cacgggccac ccggcagccg gaaaaaccaa gctgccggga cacggcgcac
     3901 aaggaatctt taataacaga ggaatccgga gtcagcacgc cggaatcatg aacaagagca
     3961 tgcctcccac caagaatttt cttctgtccg gtggaaattg gattgcctgc accccgccgc
     4021 cgcttcataa tgccgcatat atgaacatcc ggattctgag cgatgggaaa cagggccacc
     4081 tcaaccagtc cctggggctg gcgcaggctc tgatctccaa agcgggggga accgtggaaa
     4141 cggtggacct gcaggggctt tcccttttgg ggaaaatccg gaaggtcgtc acaggcagcg
     4201 acattccacg gccggatctg ttcatttccg ccggacatgc aacgcatatc ccgctcatct
     4261 gcgcgcggca ccatttcaaa acccgggccg tcctctgcat gaagcctacg cttccctgct
     4321 cctttttcga cctctgcctt attccccgcc atgacctgga ttccggccgc gattacacgg
     4381 atacggatat cttccccacc cagggagctc tccaccccat gaggccggat ccctccgtac
     4441 caaaggatac cacactgatt ctcataggag ggcccagcaa agattttgac tgggatgacg
     4501 aaagcatgct caaccagctc gcgtccatca gcatccacac ccccggacac cttgttctaa
     4561 ccacctcgcg ccggacgccg gacggctttg cggaaaaaat ccggacggcc gttccggaac
     4621 taaccgtcgt tcccgtggag gaaacccggc cggggtgggt agcccggcat ctggcgcacg
     4681 cctccgccgc ctgggtcagc caggacagcg tctccatggt atatgaggct cttggctccg
     4741 gcgcgcctgt aggcatcctt tccgtaccgc gccgacacgg cagccgcaaa tcccgcatcc
     4801 tgtccggcct ggagacactg gaaaaggaag gcatggttac tggatacagt gactggaaaa
     4861 aacagaactt ccgcctgacg gctcccggtt ccccgcttct ggaagcggac cgtgcagcag
     4921 actacatcct ctccagattt ttccctcagc tccgcgccct atgaaaatag tacatctcgt
     4981 cccctccatg gaatccggag gcgtggaaca agtcgttatg gaactgggca gcggcctttc
     5041 ttcccggggc gtggaaaata tcgtcgtttc cggaggcgga cgcctggtgc cccgtctgga
     5101 aaaggaaggc tcccgccaca tcctgatgcc gataggcaaa aaaagcatct ccactctctt
     5161 ccgcatcggg gccctccgcg ccctgcttca ggccgtcagg ccggatatcc tgcatctcca
     5221 ttcccgcgtt cctgcgtggg caggctacct ggcatggaaa aagctcccgc cggaagaccg
     5281 ccccggcctc gtcaccagcg ttcacggctt ctactccgtc aaccggtact ccgccatcat
     5341 gagccgggga gagagggtga tcgccgtctc caactgcatc agggactaca tccttgacca
     5401 ttatccgtcc acccctccgg accatatcag aatcataccc aatgctattt ccccggacca
     5461 atatcacccg gcctactccc cctcccggga atggctcacg ggctggttca tgtcctatcc
     5521 tgaactgaag gggaaattca ccctgtgcct gccgggccgc atcacgcgcc tgaaagggca
     5581 tctggatctg attccggtcg tcaggcagct tctggaacag ggaatcccgg cccacgccgt
     5641 cattgtagga gaagcaaaga agggaaaaga agaatataaa aacgaggtcc tgcgggcaat
     5701 agaacgttcc ggcgtctccc agtccttcac ctggacagga catcgccagg atctgaggga
     5761 aatcctttcc acatgttccg tcaccctctc cctgaccaaa agcccggaag ccttcggcaa
     5821 atcaaccctg gaggcgctcg ccctgggcaa acccgtggcc ggatacgccc acggcggagt
     5881 caaggaacag ctggacgcct tccttcctga agggaacgtc gccgtaggag ataccgccgc
     5941 catggcggac ctgctggccc gctggcatgc ccagcccccc cccctgcccc ggcaaattcc
     6001 ttccccttac aatatgcagg atatgattca agcccatctg gacgtttacc aggaactgac
     6061 cccttattca tgacaccccg ggaagcagcc atagccctga acctgatacc gggcctgggt
     6121 cctgtcagaa tcatgcgtct cctgcaggta ttcgcctctc cggaactgat tctggaatcc
     6181 ccttcctccc tgttgatgga aattcccggc gtgggagcgc agctggcttg ccgcatttcc
     6241 tcttggcgga gcatcgtcaa cccgtacagg gaactggaac tggcggataa cgcgggggcc
     6301 gcagtaacca cggtttttga cgactcctac ccatcctccc tgcgtgctct cccagacccg
     6361 cccattgtcc tctactcctg gggaaactgg accgggacgg atgccgaacg ctccattgcc
     6421 gtcgtcggct cacggatggc cacccattac ggcaggcttt gcgccagaaa catctcccat
     6481 gacctggcgg aagccggagt caccgtcatt tccggactgg cgcgcggtgt ggacacggaa
     6541 gcccataccg gggccatgga cgcggagggg cgcaccatcg ccgttatcgg ggcaggactc
     6601 aacaaactgt atcctcggga aaacagaaac ttggcgcagc gcattgcgga cgggcatgga
     6661 gcggtagtct ccgagtttcc aatggacctg cccccctccc gcaccacttt tcccatgcgc
     6721 aaccgcatcg tgagcggctg gagccgcgct acgctggtgg tggaggcgtc cggacgcagc
     6781 ggggccctga tcacggcccg aacggcggcc gaacagggtc gagacgtttt ttgcattccc
     6841 ggaccggttg accggcattc ttccgacgga tgccatgccc tcatccggga cggagccatc
     6901 ctggctaccg gagcctccga tattctgcag gacatgaact gggccgttcc ggaacaggga
     6961 ctgcctctct tctcgccatg tccccctgcc ggagcctcaa ccccaccgct tcccactttg
     7021 gaagaaaagg agattctcca cgccatcaga ctgggtttca atactattga caccctctgc
     7081 acctctctgg gaaaaacggc gcataccatc accccgcttt tggccaaaat gcaaattgca
     7141 gggcaaatta ctccggacgc cggagggtat ttctccatta acggcaggga actttaggca
     7201 gattccgctt ttccgccggg gaaaacgcca ggtccgggcc tcctctccct gaccatggaa
     7261 ccggaaggga gcgccgtcca tctcccgtat aaaaaccttt ccatccggac gcaaaaaaaa
     7321 cgtctcaaaa tagtcgccaa atcctttcct tcaataattt ttattccaaa aattaaatat
     7381 atcggcagga catccccggc attttaaatg cctgcggcaa atttacatgc ccgcgaaaaa
     7441 caaaatatgt tcggaaaaaa tttctgccat atttactgga cgcaggctcg ggcgcatacg
     7501 gcaacacctc ttaaaaagaa ctgttgacga atatattttg aacgcatccc tcctgcctgg
     7561 agtctcatcc ttcacaagat ctgtccgacg gatggaaaaa gcaattcaaa atccgttcag
     7621 ggtggttttt ggttccatag gtagttaata gagagaaaag gccgcggatt gtccgatccg
     7681 cggccttttt cgtccggctc tctttcaaat gcggagtttg ggcttgatga acgaaacttc
     7741 ttactgtagc aacaagacat gcgtttattc gcccttcttg caggattctc cctttgcctg
     7801 agctccacaa gctgccaatc gtacggggat tcaagtgact acatccccct cgcaacgccc
     7861 gttcccccac aactctccca gccggtttcc catgccctcc cccgaccggc caatttcccc
     7921 acacgtcctg tagccatccc ctcaagcgcc ccacgcacgc cccgctgcgc cagcgcctgc
     7981 gttatggacg ccctcaccgg caaagtgctc ttttcccaca acggcctcca gcaccgccag
     8041 gtagccagca cgcagaaact cgtgacggcc atggtcgtga tggaacacgg cagcctggac
     8101 aaaaaagtgg tcatccagcc ttccgatacc aaagcggacc ccaccaaact gggattccgg
     8161 gcgggggaag tctattcacg ccgcgaactg ctcaatgcca tgatgatccg cagtttcaac
     8221 gacgtagccc tggctctggc ccgcgatacg gcgggttccg ttccccgttt cgcccagttg
     8281 atgaatgcca aagcccggca gatgggcatg tacaactcac gcttcgccaa tcccaacggc
     8341 ctcccggcag atcaatattc cactgccatt gacatggccc gctgcgccta ttacgtgtac
     8401 cgcaacccgg aactgcgcaa tattatctgt aaacgccaat atgcctttac ccgagccaac
     8461 ggcagaacgc ttctgctgag aaacaccaac aagctgctca cacagaaccc ctgggttacc
     8521 ggaatgaaaa ccggatacac gaacgccgcc ggacgctgcc tggtttcctc agccggcgtc
     8581 aacgggcgcc atgtcatcgt cgtcgtcctc ggctgccatc cgtcccgtat ctggacggaa
     8641 tcggaaaacc tgatcagatg ggctttggga tccgccgcat aaatgcccgt cggcaattgg
     8701 tatttgactt tcacggcgtg acccgctatc agtcctgcct atgttacagg caggtattgt
     8761 aggtctcccc aacgtcggca aatccactct attcaatgcg gtcacccgga cgcgcaaggc
     8821 ccaggcggcc aactatccct tctgcaccat tgacccgaac gtgggtatgg taacagtccc
     8881 ggatccccgc ctgcaggttc tttccgacat gtccggttct gaaaaaatca tccccacgct
     8941 tattgaattc gtggatattg ccggtctggt caagggagcc tcggaaggag ccggcctggg
     9001 caaccagttt ctggcgaaca tccgtgaagt ggacgccatc gtgcaggtag tccgctgctt
     9061 tgacaatgat gatattatcc atgaactcgg ttccgtggat cctctgcgcg acattgacat
     9121 catcaactcg gaactcattc tggcggatat cgccaccatg gaaaagagac tctcttcccg
     9181 cgaacgcaag gcacgcagcg gcgacaagga agccaaggcc gaagtggccc tcatcaccaa
     9241 actcctgccc cacctgaacg aaggcaatcc cgccctcacc cttgaaccgc agctggacga
     9301 cgacgaacgc aagctgctcc attctttcca gctgctttcg gataaaaaaa gcattttcgc
     9361 ctgcaatgtc aatgaagacg aactggcgga cgccatctcc aacccggacg cccatcccta
     9421 cgtctcccag gtgaaaaaat acgtagcgga acaccataac gcggaagcca ttgtcatctc
     9481 cgcccggatt gaagaggaac tcatcgacgt ctcggaggaa gaatcccgcg aattcctgga
     9541 atccctgggt gtgaaggact ccggtgtttc cgaccttatc cgcgccgtgt accaccttct
     9601 gggcctgcgc acctacctca ccacgggaat caaggaaacg cgggcctgga ccattccggc
     9661 cggggcaaaa gcaccccagg cggccggcgt catccacacg gactttgaac gcggttttat
     9721 cgccgcggag gtagtgcact acgacgactt ggtttcctgc ggcggcaagg ccggagcgag
     9781 ggaacacggc aagctgcgca tcgaaggaaa agaatatgtc gtcaaagacg gggacgtcat
     9841 cgaattccgc ttcaatgtct agacggaagc gttaccggaa ttccattgac ttttactgat
     9901 ataaggggca gattgctcat aaccttcaca tcgcctcatg actgatacag acgtcaaatc
     9961 cacccccctg gcaactaaac acgttgaact gggagccaga atggttcctt tcgccggctg
    10021 gaatatgccg gtgcagtaca ccggcattct ggacgaacac aaagcagtgc gcgaaacctg
    10081 cggcattttt gacatctccc acatggggca gttcacggta gccggcggtt ccgctgcagc
    10141 atggctgaac tccatgctga ccaatgacat caacaaactg aatgtagggc aggggcaata
    10201 ctccgtcatg ctcaatgaca gggccggagt cattgacgac ctcatcctgt accggatgga
    10261 accggaaacc ttcttcgtag tggtgaacgc ctccaagatt gatgaagact tcgcatggct
    10321 ttccgcccat caacctgcag gcgtaactct ggaaaaccac tccgacgaat acgtggggct
    10381 ggctgttcaa ggtcccgaat gcggagaagt attctcccgc gtcatccccg gcgtggaact
    10441 tcccccccgc aatggaatct cccgcatcac ggcggaaggg acggatctca ttatctgccg
    10501 caccggctat accggggaag atggttttga attcttctgc ccggctaagg aaggcgtcaa
    10561 atggtttgaa gcctttcttg gagcaggagc caaaccctgc ggcctgggcg cccgcgacag
    10621 cctgcgtctg gaaatgtgct atcctctgaa cggctccgac ctctctccgg acaaaacgcc
    10681 tctggaagcc gggctcggat tcttctgcgc gctggatacg gacttcatcg gttccgatat
    10741 tctccgggaa caaaaagcca acggcctcag ccgtcggctg gccgctattg aatacaccgg
    10801 caagggagct cctccccgcg cccactatgc cgtgcacgtc cccggcggag aagccatcgg
    10861 agaacttacc agcggcgtgc tctctccttc gctgatgaag ggcattgccc tggcctacct
    10921 gcctgccgcc tatgccaagg tcggcacgga gctggaaatt gacgtaaggg gaaggaaatt
    10981 cccagccgtg gtcgtaaaaa aaccctttta taaaaaaggc tgacactacg gcgcaaaaat
    11041 aaactgacaa acacctcatt ttactacact ctcacttcaa acaattacat cttatgcacg
    11101 acgtaccaga aaatctgctg tattccaaag atcacgaatg gattgaaatt gacggggaca
    11161 tcggcaccat cggcatttcc gaccatgccc aggccgaact ctccgatgtc gtctttgtag
    11221 accttcccga agtaggcgcc accgtcgcag ccggcgaccc tgtcgctgtc gtggaatctg
    11281 tcaaagccgc cagcgacgtg tacacccccg tttcaggaga aatcctggaa gtgaacgaag
    11341 agctttccaa tgatccgtcc ctcattaact ccgaccccta cggcgcaggc tggctgtaca
    11401 aaatccgcct ggacgttccc acggaaacgg aagatatgat gaacgccacg gattacgagg
    11461 aatactgctc ctgaaccatt cttccctccc ccgccccggt gattccatcc cggggcattt
    11521 tgtttggccc gttccgcggc cggacgctat taccagccag agataccaca tgaataccca
    11581 ctcagatttt gccagccggc acatcggccc ccagggggaa gaacgccggg aaatgcttga
    11641 cagcctcggc taccggacgc ttgacgaact cattgcggac atcgtccccg cagatatccg
    11701 catgaaggcc ccgctggacc tgcccgcagc caaatcggaa acggaagccc tggaggaact
    11761 ccgttccatt ctgcggaaaa acaagctcct gaaaaccttc attggccagg gctattacgg
    11821 caccatcact ccctccgtca tcctccgcaa tgtactggag aaccccggct ggtacacggc
    11881 ctacacccct tatcaaccgg aaatcgccca gggacggctg gaaatgctca tgaatttcca
    11941 gaccatggtc tcttccctga caggactgcc ggtagcgaac gcctccctgc tggatgaagg
    12001 caccgcagca gcagaagccg tcaccatgtg ccggaacgcg cgccccaaag caaacacctt
    12061 ctttgtggcg gacacctgcc acccccagac catcagcgtc atccgtaccc gcgccgcctt
    12121 ccagggcgtt aacatcatcg tgggagattg ctcatccttt gaccccgcat ccatcggtgc
    12181 ggatctggcc ggagtgcttg tccaatatcc ggacacgctc ggccgcatct gcgactacac
    12241 ggacttcttt tcccgcgtgc atgccacggg cgcgctctgc gtcgtggcgg cggatctcat
    12301 ggcccttacc atcatccggg aacccggcgc cttcggagcc gatatctgca tcggcaacac
    12361 gcagcgcttc ggcatcccaa tgggcttcgg cggcccccat gccgcctaca tgtcctgcac
    12421 ggacgctctc aaacgccgca tgcccggccg ccttatcggc atgtccatag ataccctggg
    12481 ccgcccggcc taccgcctgg ccctgcaaac gagggaacag catattcgcc gcgacaaggc
    12541 gacctccaac atctgcaccg cccaggtgct cctggccgtg cttgccgcct tttacgccgt
    12601 ataccacggc caggaaggcc tcaaacgcat cggcacggaa atccacttga aaaccaaaag
    12661 cctgtacaag gcgctcacgg aagccggcat cgccattgaa aacaaaaact tctttgacac
    12721 cctgctgctg tccgttcccg gacaagcgga cgccatggtg caaaaagccc tggaagccgg
    12781 gtataacatc cgcagggtgg atgccgacca cgcagccatc tctctggatg aaaccgcaac
    12841 ctgtgcggat atagcggcac tggcctccgc ccttgcaggt gcggaaacat ccgccacctg
    12901 cgattgcgac gctcctgcct gggatcccgt ccacacgcgc cagacgcctt tctgcacgga
    12961 aaaggctttc aactcctacc attccgaaac ggaaatgatg cgctacatcc gccgcctgga
    13021 atcccgggac ctggctctaa atgaagccat gatccctctg ggctcctgca cgatgaagct
    13081 gaatgccgcc tctgaaatga ttcccatcac gtggccggaa gccaactccc tgcatccctt
    13141 tgttccggcg gaccagtcgg aaggcatccg ggaaatgctc tccgtcctgt ccgaccgtct
    13201 ggcgaaaatc accggctttg ccgccgtctc cctccagccc aacgcgggcg ccgcagggga
    13261 atatgccggg ctactggcca tccgccgtta ccagaagcac gccggagaag gccaccgcaa
    13321 tgtctgcctc attcccacct ccgcccacgg aacaaatccc gcctcctccg ccatggccgg
    13381 cctcaaggtg gtgcccgtca aatgcgacga aagaggcaac atcgacatgg tagacctgaa
    13441 atcccaggcg gaagcccata aggacaatct ttcctgcatc atggtcacgt acccctccac
    13501 gcacggggta tatgaacaga caatcaagga actctgcgac atcgtccatg ccaatggcgg
    13561 ccaggtgtac atggacggcg ccaacatgaa tgcccaggta ggtctgactt gccccggctg
    13621 cattggcgcg gacgtctgcc acctgaacct gcataaaacc tttgccatgc cgcacggcgg
    13681 cggcggtccc ggcatcgggc ccatcggcgt agcggaacac ctcgtaccct tcctgcccgg
    13741 acacctcacg ctgggccatg aagaaggggc cgtagcgtct gcggcgtggg gaagcgcctc
    13801 catcgccgcc atctgctgga tgtatctctc catgatgggg ccggacggcc tcagggaagc
    13861 cacggaaatg gccatcctta acgccaacta cattgccaag aaactcggac atctcttccc
    13921 ggttctctac tccggcaaca aggggctggt ggcgcatgaa tgcattctgg atccgcgcca
    13981 gctcactcat gacgccggcc tcacggtgga tgacattgcc aaaaggctca tggactacgg
    14041 cttccacggc cccaccatgt ccttccccgt tccgggcacc ctgatggtgg agccgacgga
    14101 atcggaaccc aaaaaagaac tggaccgctt cattgaagcc atggaacgca ttcatgcgga
    14161 aatcacggcc attatcaacg gtacagcaga caaggaagac aacgtcctga aaaactcgcc
    14221 ccataccgca gaaatggtct ctgccgacga atggcggcat ccctactccc gcagtgaagc
    14281 ggcttatccg gtctccggtc tccttattca caaattctgg ccgtatgtag gccgggtgga
    14341 taatgtgtac ggagaccgca atctggtctg cacctgcgac acggtggagg aattctccaa
    14401 ggccgtagag ttataaaaat ctcatccttc ctttcaaaaa ggctgttcca ttcatttgga
    14461 gcagcctttt tcttatgttc aagaatcgga tttctaatcc gaag
//
