LOCUS       c00069_gnlPro..        13315 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FKPEBNDH_69.
ACCESSION   c00069_gnlPro..
VERSION     c00069_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 13:24:50
            Original ID  :: gnl|Prokka|FKPEBNDH_69
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13315
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13315
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[15:3315]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      16..3315
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..13315
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13315
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(16..1008)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg69_1"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 2.1e-119,
                     bitscore: 387.9, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKLIVSLSPHVHGGDSVKKNMYGVLIALIPAFLVSLYFFGLGAL
                     IVTATSVAACLFFEWAIGKFLMKKETTTITDGSAIITGVLLAFNLPSNLPIWIIILGAL
                     FAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTTWPAVGQLTAYTDATTAATPLA
                     IMKGVINGAPGMSLSDLPGAFDLLIGNNGGCLGEVSALALLLGLFYMLWKKIITWHIPV
                     SILVTVFVFSGIMYLVNPELYVSPVVQLLSGGLMLGAVFMATDYVTSPMSHKGMLIYGV
                     CIGLLTVIIRLFGAYPEGMSFAILIMNAFTPLINTYVKPKRFGEVAKKK"
     CDS             complement(1015..2352)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg69_2"
                     /sec_met_domain="Fer4_10 (E-value: 1.9e-09, bitscore: 27.3,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 3.9e-16, bitscore: 48.5,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 1e-49, bitscore:
                     158.1, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 4.6e-30, bitscore: 93.4,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.6e-05, bitscore: 14.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIIKAEIPAKAAILLGQHIGAPAK
                     PIVAKGDVVKVGTKIAEPGGFVSAAIHSSVSGKVAKIDTIVDASGYAKPAIFIDVEGDE
                     WEESIDRSETLVKECSLTSEEIVKKIADAGIVGLGGACFPTQVKLCPPPAFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEIMVGVSILMKAVKVNKAFIGIENNKPDAIQLMTKVASS
                     YAGIEVVPLKVQYPQGGEKQLIDAVISRQVTAGALPISTGAVVQNVGTAFAVYQAVQKN
                     KPLFERVITVTGKSLAKPSNFLARIGTPMKQLIEACGGLPEDTGKIIGGGPMMGKALVN
                     TDVPTAKGSSGILIMNEKEAKRGEVQPCIRCAKCVGACPMGLEPYLLATVSAHGDFERV
                     EKEDIMSCIECGSCQFTCPSNRPMLDYIRLGKGKVGAMIRARQAKK"
     CDS             complement(2413..3315)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 37.6; E-value:
                     8.3e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg69_3"
                     /sec_met_domain="Fer4_7 (E-value: 1.6e-12, bitscore: 37.6,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 9.1e-10, bitscore: 27.9,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 4.9e-09, bitscore: 25.8,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 5.1e-09, bitscore: 25.8,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 1.1e-11, bitscore: 34.0,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 5.8e-06, bitscore: 16.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVILIAVISLGVIALVSAAILYVASKKFAVYEDPRIAQVAEVLP
                     QANCGGCGYPGCSGFADACVKAGSLDGKLCPVGGQPVMTKIAEILGLDAAAAEPMVAVV
                     RCNGTCANRPRVNQYDGAKSCAIAASLYGGETGCGYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEEKCTACGACAKACPKSIIEIRPQGKKSRRVYVQCVNKDKGAVARKACTVACI
                     GCGKCVKVCPFEAITLENNLAYIDPNKCKSCRKCEEACPQNTIIALNFPPRKPKADDAA
                     PQVKVAAPKAEVETPKAEV"
     CDS             complement(3353..3772)
                     /locus_tag="ctg69_4"
                     /transl_table=11
                     /translation="MANTIKHQGIVENINGSHLQVRIIQTSACASCSVKGHCTSADTKE
                     KLVDVADADAASYQPGDRVWVTGELSMGVMAVLFAFIFPFLILIISLFVFMAIWNDELR
                     SALCSLALLVPYYYILWLNKSRMGKKFSFSVRPMN"
     CDS             complement(4003..5430)
                     /locus_tag="ctg69_5"
                     /transl_table=11
                     /translation="LVNCYDDFFVGDGTEYAGYRLEEQWTGXXXETTAKADTLPDIMKE
                     YMILKLKPEGMGYRLDTVSILYERYIGVLDYLNDPTTPERYIPSNPNYYRLFLPLTYYY
                     APMRRLSKVDWHFQVPDTVPALTREMLPFDTLSFTSKDRANKLVDRTLLNTYVNCPNLV
                     VMTEKEVMKGKIFKDNIEKEVSSKPSVVKLFAQENMVGVKEEADVIIHKPNWWVTGGNG
                     SLQITQNYISDNWYKGGESTNAVLANLQLFANYNDREKVQWENLLDAKLGFSSAPSDEF
                     HNYLVSTDQLRLYSKLGIQAASKWYYTITTEFKTQFCNGYKANSEELVSAFFAPADWSS
                     SIGMDYKLKKQKFSLSVFMAPLTYMLRYVGNKGVNEVSFGLDEGKCVKHNFGSQIQPTL
                     SWTIIPSITLDSRLDFQTSYEWTRIEWENTVNFVLNRYLSTKLYVHARYDDSAKPTEGD
                     SYFQVKELLSFGINYKW"
     CDS             complement(5486..5692)
                     /locus_tag="ctg69_6"
                     /transl_table=11
                     /translation="MPRAYTACRSRCILLPSVHVELKKRKIIKKRGSRESFDETIIKKY
                     DFIEESPSCLFLMAFLCFLNILS"
     CDS             5724..7343
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg69_7"
                     /sec_met_domain="GATase (E-value: 7.1e-55, bitscore: 175.4,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGETKYIFVTGGVASSLGKGIISSSIGKLLQARGYKVTIQKFDPY
                     INIDPGTLNPYEHGECYVTVDGHEADLDLGHYERFLGIQTTKANNITTGRIYKSVIDKE
                     RRGDYLGKTIQVIPHITDEIKRNVKLLGNKYKFDFVITEIGGTVGDIESLPYLESIRQL
                     KWELGKDALCVHLTYVPYLAAAGELKTKPTQHSVKELQSAGIQPDVLVLRTEHELSTTL
                     RKKVALFCNVDENAVVQSIDAPTIYEVPILMQSQGLDVTILKKMGLPVGDTPGLGPWRA
                     FLERRHKAEETAPLHIALVGKYDLQDAYKSIREALSQAGTYNDRKVSVDFVNSEKLTDE
                     NVAEALKGMAGVLIGPGFGERGVAGKFVAIKYARTHDIPTFGICLGMQCIAIEFARNVL
                     GYADANSREMDEKTPHNVIDIMEEQKSITNMGGTMRLGAYECVLQKGSKAYEAYGTEHI
                     QERHRHRYEFNNSFKDAYEAAGMKCVGINPESDLVEIVEIPALKWFVGTQFHPEYSSTV
                     LHPHPLFVAFVKAAIENENEKK"
     CDS             7375..9228
                     /locus_tag="ctg69_8"
                     /transl_table=11
                     /translation="MDKNTITGLVLIAILLVGFSFLSRPSQEQLEAQQRYYDSIAQVQQ
                     READLKAKAEAALANESGAEASVDSTALFFDARQGTNSQVTIQNNLAEITVDTKGGRIA
                     SATLKEYMGQDKTTPVTLFSGNDASMNFLFYNKKETIQTEDYYFTAVNRTDSTVTMRLS
                     ADSNSYIDFTYSMHNDTYLIDFTIQAVNMEGKLAATNNYVDIEWSQRARQIEKGYTYEN
                     RLAELTYKITGEGTDYLSANKNDEKEVPERLDWIAFKNQFFSSVFLADADFEKTKLSSK
                     METQGSGYIKDYSAEMSTKFDPAGKEPTQLFFYFGPNHYKTLTALDKGRDDKWELNRLV
                     YLGWPLIRWINKWFTINIFDWLSSWGLSMGIVLLFMTLIVKAVVFPATWKTYMSSAKMR
                     VLKPKIDEINKKYPKQEDAMKKQQEVMGLYSQYGVSPMGGCLPMLIQFPILMALFMFVP
                     SAIELRQQSFLWADDLSTYDAFINFPFHIPFLGSHLSLFCLLMTVTNILNTKYMMQQQD
                     TGANPQMAAMKWMSYLMPVMFLFILNDYPSGLNYYYFISTLVSVVTTLIMRKTTNEEAL
                     LAQLEANKKDPKKMKKTGFAARLEAMQKQQEQMMKEKQNKK"
     CDS             9331..10662
                     /locus_tag="ctg69_9"
                     /transl_table=11
                     /translation="MQTKYTYKQIWLIAYPILISLLMEQMIGMTDTAFLGRVGEVELGA
                     SAIAGVFYMVIFMVAFGFSIGAQILIARRNGERQYKEIGDLFYQGIYFQVGMAAVMFLL
                     SYCFSPIILKRIVASEHIYEAATSYLHWRVFGAFFSFSAVMFRAFFLGTTQTKTLTLNS
                     IVMVLSNVVFNYILIFGKFGFPALGIAGAAIGSSLAELVSLLFFILYTRSRIDCCKYGL
                     DRIPKFRLDVLKRMLNVSFWTMIQNFFSLSTWFLFFLYVEHLGERSLAVTNIVRNVSGI
                     LFMVLMAFASTCGSLVSNLIGAGHSDCVAGTIRQHVRIAYVFVLPLALLFALFPKLILG
                     IYTDIPDLQDAAVHSLWVMCSTYLFLVPANVYFQAVSGTGNTRTALGMELATLVIYTAY
                     ITYIILILQLDVAICWTSEMVYSSFILIFCWLYIKRGNWQGRKI"
     CDS             10724..12823
                     /locus_tag="ctg69_10"
                     /transl_table=11
                     /translation="MSAAMTLASCGGTKDAGQQQDAAVLIQRSDIKIEGKRMTPEALWA
                     MGRIGSVAVSPDEKQIAYTVSYYSVPQNKSNSEVFVMNADGSGNTQITHDAWQEGQPTW
                     FKDGKKLAFLCNESGSSQVWEMNPDGSGRKQLTQYEGDIEGFSFSPDGKKLLFIAQVKT
                     VKSTADKHPDLPKATGIIVTDLMYKHWDEWVTTAPHPFVADFDGNAISNVTDILEGEPY
                     ESPMKPWGGIEQLAWSPSSDKVAYTCRKKTGLAYAISTNSDIYIYDLASKETKNITEEN
                     KGYDTNPQYSPDGKYIAWQSMERDGYEADLNRLFIMNLETGEKRFVSKAFESNVDAFLW
                     NKDSRSIYFIGVWHGETQIYNIDLAGNDKLTQLTDGMYDYASLALCGDKIIAKRHSMSM
                     GDEIYAVNSARNGDAFAEAVQLTTENKQIYDQLEMGKVEARWMKTTDGKQMLTWVIYPP
                     QFDPNKKYPTLLFCEGGPQSPVSQFWSYRWNFQIMAANDYIIVAPNRRGLPGFGVEWNE
                     AISGDYGGQCMKDYFTAIDEMAKEPFVDKDRLGCVGASFGGFSVYWLAGHHDKRFKAFI
                     AHDGIFNMEMQYLETEEKWFANWDMGGAYWEKNNATAQRTFANSPHLFVDKWDTPILCI
                     HGEKDFRILANQAMAAFDAAVMRGVPAELLIYPDENHWVLKPQNGVLWQRTFFEWLDKW
                     LKPAK"
ORIGIN
        1 atgattctaa ctttttcatt tcttcttcgc tacctcccca aagcgtttag gtttaacata
       61 ggtgttgatg agcggagtga acgcattcat aatcagaatg gcaaacgaca taccctccgg
      121 atatgcaccg aacagacgga tgatgacagt cagtaggccg atgcaaacac cataaatcag
      181 catacctttg tggctcatcg gagaagtcac gtagtccgta gccataaaga cagcacccag
      241 catcagacca ccggacaaca actgtacgac cggggataca taaagttccg gattgaccag
      301 atacatgata ccggagaaca cgaataccgt caccagaata gataccggaa tgtgccaggt
      361 gatgattttc ttccacaaca tgtagaacaa accaagcagc agcgccaagg cactcacctc
      421 accgagacat cctccattat tacctatcag aaggtcgaaa gctcccggaa ggtcgctcag
      481 ggacatgccc ggagcaccat tgatgacacc tttcataata gccagcggcg tagcagctgt
      541 cgtggcatcc gtataggctg tcaactggcc tacagccggc catgtcgtca tctgcacggg
      601 gaatgaaagc aacaggaaca cacgtcctgc cagtgcaggg ttaaagggat tgcaacccaa
      661 acctccgaag gacatcttgc ctaccccgat ggcaaacaag gcaccaagga tgataatcca
      721 gatgggcagg ttggaaggca ggttaaaggc cagcaacaca ccggtaatga tggcagaacc
      781 gtcggtaatg gttgtggtct cttttttcat gaggaatttg ccgatggccc attcaaagaa
      841 caagcaggct gctacggaag tggccgtaac aatcagcgca cccagtccga aaaagtaaag
      901 cgaaacaagg aatgccggaa tcaatgcgat aagcacaccg tacatattct tcttcacgct
      961 gtcaccgccg tgaacgtggg gcgaaaggga tacgattaat ttattcatac ttcgttattt
     1021 tttagcttga cgtgcacgga tcatcgctcc taccttaccc ttacccaagc ggatataatc
     1081 cagcatcgga cggttggaag gacaagtgaa ctggcatgaa ccgcattcta tacacgacat
     1141 aatgtcttct ttctctactc tttcaaaatc tccgtgggcc gaaacggtag ccagcagata
     1201 cggctccaac cccatcgggc aggctcccac gcacttagca caacggatac aaggctgtac
     1261 ttcgccgcgc ttggcttcct tctcgttcat aatcagaata ccggagcttc ctttggctgt
     1321 cggtacatcc gtatttacca gagctttacc catcatcggg ccaccgccga taatcttgcc
     1381 cgtatcttcg ggcagaccgc cgcaagcttc aatcagctgc ttcatcggcg taccgatacg
     1441 tgccaggaaa ttggacggct ttgccaacga cttaccagtc acggtaatga cacgctcaaa
     1501 cagaggtttg ttcttctgta cggcctggta aacggcaaat gcggtaccca cattctgcac
     1561 cacagctccc gtggagatag gcagcgcacc ggctgtaacc tggcgactga tgacagcatc
     1621 aatcaactgc ttttcaccac cctgcggata ttgtaccttc aagggtacca cctcgatacc
     1681 tgcatagctg gaagcaacct tcgtcatcag ctggatggca tcgggcttgt tgttctcaat
     1741 gccaatgaat gccttgttca cctttaccgc tttcatcaga atggatacac ctaccataat
     1801 ttcttccgca tgttccagca tcagctgatg gtcggcagtc agatacggtt cgcactctac
     1861 ggcgttgatg atgacacact ctgccttgaa tgcaggagga ggacacaact tgacctgcgt
     1921 aggaaagcat gcaccgccca gacctacgat accggcatca gcgattttct tcacgatttc
     1981 ctcggaggtc agactgcatt ccttcaccaa cgtttcggaa cggtcaatgg attcttccca
     2041 ttcatcccct tctacgtcaa tgaatatagc aggcttggcg taaccgctgg catcgacaat
     2101 cgtgtcaatc ttagcgactt tcccgctgac agacgaatga atggctgctg atacaaaacc
     2161 gccgggctcg gcaatcttcg tacccacttt cacaacatca cctttggcaa cgataggctt
     2221 ggcaggagca ccgatgtgct gtcccagcaa gatagcggcc ttggccggaa tctctgcctt
     2281 gatgataggc tgatgtgctg aaagtttatt ttcgtgtgga tggactccac caattgaaaa
     2341 tgtcttcaac atacaattct gtatttttag tcgtttattt actttattaa ttcatacctc
     2401 aacttgggaa gtctaaacct ctgctttggg agtctcaacc tcagctttag gagctgcaac
     2461 ctttacttgg ggagctgcat cgtcagcctt cggtttgcgc ggcgggaagt tgagggcaat
     2521 gattgtgttt tgcggacaag cttcctcgca cttgcgacag gatttgcact tattggggtc
     2581 aatgtaagcc agattgtttt ccagcgtgat agcctcgaac ggacaaacct tcacacactt
     2641 gccgcaaccg atacatgcca cggtacaagc cttgcgtgct acagccccct tgtccttgtt
     2701 tacacactgt acgtaaacac gacgtgattt cttgccttga ggacggattt caatgataga
     2761 tttcggacaa gccttggcac aagctccaca agccgtacac ttttcctcat ccacttcggg
     2821 aagtccggtc tccggattca tgtggatagc atcgaactgg caggcagcca cacagtcgcc
     2881 gcatcccaga cagccataac cacaacccgt ttcaccacca tagagagaag ccgcaatggc
     2941 acaactcttg gcgccatcgt attggttcac acgaggacgg ttggcacaag ttccattaca
     3001 tctcaccacc gcaaccatag gttcggcagc agcggcatcc aagcccagaa tctcggcaat
     3061 ctttgtcatg acgggctgtc cacccaccgg acaaagttta ccatccagcg aacctgcctt
     3121 tacgcaagca tctgcaaatc cgctacaacc ggggtaacca catccaccgc aatttgcctg
     3181 gggaagcacc tctgctacct gggcaatccg cggatcttca tacacggcga atttcttgga
     3241 agccacgtaa agaatagcgg ccgataccag cgctataact cccaatgaaa tcactgcaat
     3301 cagaattaca ttcataaatt agttgtttat taattatttg ttttattatt agttagttca
     3361 tcggtcgtac ggagaatgag aacttcttac ccatccgcga cttgttcagc cacaatatat
     3421 aataataagg tacaagaagt gctagcgaac aaagcgcgga acgcagctcg tcattccaga
     3481 tagccataaa gacaaacagt gagattatca gaataaggaa aggaaatata aaggcaaaca
     3541 gaactgccat cactcccatt gaaagttcgc ccgtcaccca tacacggtcg ccgggctggt
     3601 aggatgcggc atcggcatcg gccacatcga caagtttctc tttcgtatcc gcagaggtac
     3661 aatgtccctt gacactacac gaagcgcatg ctgaagtctg gatgattctc acttggagat
     3721 gagaaccgtt tatgttttcc acaatacctt gatgttttat agtattcgcc attttgcaaa
     3781 gtgtgcatta caaatcgtgg caaatttacg cattatttgt gaactgcaaa cctttcctat
     3841 gtattttctg tgttcgcaaa catgcttttt ctatgttttt atgttttttc acctgccaca
     3901 gactacaaaa agacaaaaaa cagacggtct gtcaagggaa aacagaccgt ctgactaact
     3961 aaaacagata atctgttcac tccgaacaga ccatttgttt atttaccatt tataattgat
     4021 accgaaactg agcaattctt ttacctgaaa atagctgtcc ccttccgtcg gcttggcact
     4081 gtcgtcatag cgggcgtgca catagagctt ggtggaaaga tagcggttca gcacaaagtt
     4141 caccgtgttt tcccattcaa tacgtgtcca ctcataactg gtctggaagt ccaagcggga
     4201 atccagcgtg atggaaggaa tgatggtcca tgaaagtgta ggctgtatct gcgaaccgaa
     4261 gttatgcttc acgcatttgc cctcatcaag accgaaactc acttcattca cccccttatt
     4321 tcctacatag cgcagcatgt acgtcagcgg agccatgaaa acggacaagc tgaatttctg
     4381 cttcttcaac ttgtagtcca taccgatact gctcgaccag tctgccggag caaagaaagc
     4441 cgaaaccagc tcttcactgt tggccttgta gccattgcag aactgggtct taaactcagt
     4501 cgtgatggta taataccact tggacgcagc ctgaataccc agtttactgt acagccggag
     4561 ttggtcggta cttaccagat agttatgaaa ctcgtcggaa ggtgcggagc tgaagcccag
     4621 cttggcatcg agcagatttt cccactgcac cttttcacgg tcattatagt tggcaaacaa
     4681 ttgcaggttg gcaagcacgg cgttagtgct ctcacctccc ttgtaccagt tgtcggagat
     4741 atagttctgg gtaatctgca atgaaccgtt tccacccgtc acccaccagt tgggcttgtg
     4801 gataatcacg tcggcttcct ccttcactcc caccatattc tcttgtgcaa acagtttcac
     4861 gacggacggc ttggaagaaa cctccttctc tatattatcc ttgaatatct tccctttcat
     4921 cacctccttc tcggtcatta caaccagatt gggacaattc acatacgtgt tcagcagcgt
     4981 acggtccacc agtttgttgg ctcggtcctt tgaggtgaaa ctcagtgtgt cgaacggcaa
     5041 catctcgcgc gtcagggcag gcaccgtatc aggcacctgg aaatgccagt ccaccttgga
     5101 aaggcgtctc atgggggcat aataataggt aaggggaagg aacaacctat agtagttcgg
     5161 attggaaggt atataacgct ccggagtcgt ggggtcattc aaataatcca gcactccgat
     5221 atacctttca tataatatgg aaacagtatc cagcctgtac cccatacctt ccggtttcaa
     5281 tttcagaatc atgtattctt tcattatatc cggcaaggtg tcggctttgg cagttgtttc
     5341 nnnnnnnnnn cctgtccact gttcttcgag gcggtatcca gcgtattctg tgccatcacc
     5401 gacgaagaaa tcatcgtagc aattaaccaa aatgcaatgt gtctattctt cataatgccc
     5461 taaagtctat gtttcgagcg caaatttagc ttaaaatgtt tagaaaacat agaaaagcca
     5521 taagaaaaag gcaagaagga ctttcttcga tgaaatcgta ttttttaata attgtttcat
     5581 cgaaactttc tctacttcct ctttttttta taattttgcg ctttttaagt tctacgtgta
     5641 ctgacgggag cagtatgcac cttgaacgac aagccgtata ggctcttggc attagattaa
     5701 acaattaata aaataatata gttgtgggag aaacaaagta tattttcgtc accggtggtg
     5761 ttgcctcttc attaggtaaa ggtatcatct catcctccat cggtaaattg ctgcaagcaa
     5821 gaggttacaa ggtaaccatc cagaagtttg acccgtacat caacatcgac ccgggtacac
     5881 tgaaccctta tgaacacggc gaatgctacg ttaccgtgga tggccacgaa gccgacctcg
     5941 atttgggcca ttacgaacgc ttcctgggca tccagaccac caaggccaac aatatcacga
     6001 ccggacgcat ctacaaaagc gtcatcgaca aagagcgccg gggtgactat ctgggaaaga
     6061 ccatccaggt tattccccat attacagacg aaatcaagcg taatgtaaaa ctgctgggaa
     6121 acaaatacaa attcgacttt gttattaccg agattggcgg tacagtgggt gacatcgagt
     6181 ctctgcccta tctggaaagc atccgtcagc tgaagtggga actgggaaaa gacgccttgt
     6241 gcgtacacct tacttatgtc ccctacctgg cagctgccgg tgagctgaag accaagccca
     6301 cccagcactc cgtaaaggaa ctgcaaagtg ccggtatcca acccgatgtc ctcgtactgc
     6361 gtacggagca cgagttgagc actaccctgc gcaagaaggt ggctctgttc tgcaatgtgg
     6421 acgagaatgc cgtggtgcag agcatcgacg cgcctaccat ctacgaggtg cccatcttga
     6481 tgcagagcca gggactggac gttaccattt tgaagaaaat gggacttccc gtcggtgata
     6541 ctccgggact gggaccgtgg cgtgctttcc tcgaacgccg tcacaaagcc gaagagactg
     6601 ccccactgca catcgcattg gtgggcaaat atgacttgca ggatgcctac aagtccatcc
     6661 gcgaggccct ttcacaagca ggaacctaca atgaccgcaa agtatcggta gacttcgtga
     6721 acagtgaaaa gctgactgac gagaatgtgg cagaagccct gaaaggcatg gcaggcgtac
     6781 ttatcggtcc aggcttcggc gaacgcggcg ttgccggcaa gttcgtagcc atcaaatatg
     6841 cgcgtacgca cgacatcccc accttcggta tctgtctggg tatgcagtgt atcgccatcg
     6901 aatttgcccg taacgtactg ggttatgccg atgccaactc acgcgagatg gacgaaaaga
     6961 caccgcacaa tgtcatcgac atcatggaag agcagaagtc catcaccaat atgggtggaa
     7021 ccatgcgtct gggtgcctac gaatgtgttc tgcagaaagg cagcaaggca tacgaggcat
     7081 atggtaccga gcatatccag gaacgtcacc gtcaccgcta cgagttcaac aacagcttca
     7141 aggatgccta cgaagcagca ggcatgaagt gtgtgggtat aaaccccgaa tcggacctgg
     7201 tggaaattgt tgagattccc gcattgaagt ggtttgtcgg tacccagttc catcccgaat
     7261 acagcagtac ggtattgcat ccgcacccac tgttcgtagc attcgtgaag gccgccatcg
     7321 aaaatgaaaa cgaaaagaaa taatttgtaa taagtaattt gtaatcaaca aagaatggat
     7381 aaaaatacca tcacaggtct tgttctgata gcgatattgt tagtaggttt cagctttctg
     7441 agccgtccca gccaggagca gttggaagca cagcaacgtt actacgactc catagcccag
     7501 gtgcaacagc gcgaagccga cttgaaagcc aaggcggaag cagccctggc caacgaaagc
     7561 ggagcggaag caagcgttga ctccactgcc ctcttcttcg acgcccgtca aggaaccaac
     7621 tcgcaggtaa ccatccagaa caacctggca gaaataaccg tagatacaaa aggcgggcgc
     7681 atagcttcgg ccacgctgaa ggaatacatg ggacaagaca agacgacccc cgtcacactg
     7741 ttcagcggca atgacgcctc catgaatttc ctcttttaca acaagaaaga gactatccag
     7801 acggaagact attatttcac cgcagtaaac cgtacggaca gtaccgtcac catgcgtttg
     7861 tcggcagaca gcaacagcta tatcgacttt acctacagca tgcacaatga cacatacctg
     7921 atagacttta ctatccaggc agtcaatatg gaaggcaagc tggcggctac caacaattat
     7981 gtggacatcg agtggtctca gcgtgcccgt cagatagaga agggttacac ctacgagaac
     8041 cgtctggctg aactgactta caaaatcacc ggagagggta ccgattatct gtccgccaac
     8101 aagaacgacg aaaaggaagt tccggaacgc ctggactgga ttgctttcaa gaaccagttc
     8161 ttctcttcag tatttttggc agatgccgac tttgaaaaga ccaaactgag ttccaagatg
     8221 gagactcaag gcagcggcta catcaaggac tattctgcgg agatgagcac gaagttcgac
     8281 cctgccggca aggaacctac ccagctgttc ttctacttcg gccccaatca ctacaagact
     8341 ctgaccgcac tcgacaaggg acgtgacgat aagtgggagc tgaaccgtct ggtctatctg
     8401 ggctggccgc tcatccgctg gataaacaaa tggttcacca tcaacatctt cgactggttg
     8461 tccagttggg gtttgagcat gggtatcgta ctgttgttca tgacgctgat tgtaaaggca
     8521 gtggtattcc cggctacgtg gaagacctac atgtcttctg ccaagatgcg cgtactgaaa
     8581 ccgaaaatcg acgagataaa caagaagtac cccaagcagg aagatgccat gaagaagcag
     8641 caggaagtga tgggcctcta cagccagtac ggagtcagcc cgatgggcgg atgtctgccg
     8701 atgctgatac agttccctat cctgatggcc ttgttcatgt tcgtgccgag tgccattgaa
     8761 ctccgccaac agagcttctt atgggcagac gacctttcca cttatgatgc gttcatcaac
     8821 ttcccgttcc atatcccgtt cctgggcagc cacctcagct tgttctgcct gctgatgacg
     8881 gttaccaaca tattgaacac gaagtacatg atgcagcagc aggatacggg tgccaatccg
     8941 cagatggctg ccatgaagtg gatgtcatac ctgatgcctg tcatgttcct cttcatattg
     9001 aacgactatc cttcgggatt gaactattac tacttcatct ctacgttagt cagtgtggta
     9061 acaacgctca tcatgcgcaa gacaaccaat gaggaagccc ttcttgctca gttggaagcc
     9121 aacaagaaag acccgaagaa gatgaagaaa accggtttcg ccgctcgtct ggaagccatg
     9181 cagaaacagc aggaacagat gatgaaagaa aaacagaaca aaaagtagta agactaccgt
     9241 tcaagatatt cttttgcaga aagccggaca atgacatttg cccggctttc ttatccttac
     9301 accaacgaaa aaattcacag actctaaatt atgcagacta aatacactta caaacaaatc
     9361 tggctcatag cctaccctat cctaatcagc ctccttatgg agcagatgat aggtatgacg
     9421 gacaccgcct tcctcggacg tgtaggtgaa gtcgagttgg gagcatctgc catcgccggt
     9481 gtcttctata tggtcatctt catggttgcc ttcggtttca gcatcggggc acagatactc
     9541 attgcccggc gcaacggcga acggcagtat aaggaaatcg gtgacttgtt ctatcagggc
     9601 atctatttcc aagtcgggat ggcggcagtc atgttcctgc tatcttattg cttctcgccg
     9661 attatcctga aacgcatcgt agcctcggaa catatctacg aagcagccac cagctacctg
     9721 cactggcgtg tattcggtgc cttcttctcg ttcagcgcag tcatgttccg tgcctttttc
     9781 ttgggaacca cccagaccaa gacactgaca ctgaactcca tcgtcatggt gttgagcaat
     9841 gtcgtattca actatatcct gattttcggt aaattcggtt ttcctgcact cggcattgcc
     9901 ggagccgcca tcggctcctc attggccgag ctggtttcgc tgttattctt catcctctat
     9961 acccgtagcc gtatcgactg ctgcaagtac gggctggacc gtattccgaa gttccggctg
    10021 gacgtattga aacggatgct gaacgtctct ttctggacca tgatacagaa tttcttctcc
    10081 ctctccacct ggttcttgtt cttcctttat gtggagcatc tgggagagcg atcgctggca
    10141 gtgaccaaca ttgtccgcaa tgtgtccggc atactgttca tggtactcat ggcatttgcc
    10201 tctacctgcg gttcattggt cagcaacctc atcggtgcag gccactccga ttgcgtggca
    10261 ggcactatcc ggcagcacgt acgcatagcc tacgttttcg tacttccgct ggcattgctt
    10321 ttcgcgctgt tccccaagct gattctggga atttataccg acatacccga cctgcaggac
    10381 gctgccgtgc attcgctttg ggtgatgtgc tccacctatc tgttcctggt tcctgccaat
    10441 gtctatttcc aggcagtttc cggaaccggc aatacgcgta ctgcattggg catggagctg
    10501 gcaacgctgg tcatctacac agcctatatc acctacatta ttctgattct gcaactcgac
    10561 gtggccatct gctggacctc ggaaatggtt tattccagct ttattctcat tttctgctgg
    10621 ctatatatca aacgtgggaa ttggcaagga aggaaaattt agtatctttg cattgaaata
    10681 accgaaacaa aaaacatata tgaaacaagt aaatctacta cttatgtcag cagccatgac
    10741 attggcctcc tgcggaggaa caaaagatgc cggacagcag caggacgcag cagtgctcat
    10801 ccagcggtcg gacatcaaga ttgaaggaaa gcgtatgaca cccgaggcac tctgggcgat
    10861 gggacgtatc ggcagtgtag ccgtatctcc cgacgaaaag caaattgcct acacggtatc
    10921 ctattacagc gtgccccaga acaagagtaa cagcgaagtc ttcgtcatga atgccgacgg
    10981 tagtggcaat acccagataa cgcatgacgc ctggcaagaa ggacagccca catggttcaa
    11041 ggacggcaag aagcttgcct tcctctgcaa cgaaagcggc agcagccagg tatgggaaat
    11101 gaatcccgac ggcagcggac gcaagcagct gacccaatac gagggagaca tcgaagggtt
    11161 ctctttctcg cccgacggca agaaactcct tttcattgcc caggtaaaga ccgtgaagag
    11221 tacggcagac aaacatccgg accttcctaa agccaccggc atcatcgtta ccgacctgat
    11281 gtacaagcat tgggacgaat gggtgactac tgctccccat ccgtttgttg ctgatttcga
    11341 cggcaatgcc atcagcaatg tcactgatat tcttgaggga gagccatacg aaagcccgat
    11401 gaagccctgg ggcggtatcg agcagctggc atggagcccg tcttctgata aggtggccta
    11461 tacatgccgt aagaaaaccg gactggcgta tgccatttcc accaactccg acatttatat
    11521 ctacgacctt gcctccaagg aaaccaaaaa catcacggaa gaaaacaagg gatatgatac
    11581 gaatccccaa tactctcccg acggcaaata catcgcctgg cagagcatgg agcgtgacgg
    11641 ctacgaagcc gacttgaacc gcttgtttat catgaacctc gagaccggcg agaaacgttt
    11701 tgtaagcaaa gctttcgaat cgaacgtgga cgccttcttg tggaacaaag attcccggag
    11761 catctacttc atcggtgtat ggcatggcga gacacagatt tacaacatcg accttgccgg
    11821 aaacgacaag cttacccagc tcaccgacgg catgtacgac tatgcttcgc ttgccctttg
    11881 cggagacaag attatcgcca aacgccactc catgagcatg ggcgacgaaa tctatgccgt
    11941 aaacagtgca cgcaacggcg acgcttttgc agaagcagtg caactgacca cagaaaacaa
    12001 gcagatttac gaccagctgg agatgggtaa ggtggaagcc cgctggatga agaccaccga
    12061 cggcaagcag atgctgacct gggtgattta tcctccgcag ttcgacccta acaagaagta
    12121 ccccaccctc ctcttctgtg aaggcggtcc tcagagtccc gtcagccagt tctggagcta
    12181 ccgttggaat ttccagatta tggcagcaaa cgactatatc atcgtagctc ccaaccgccg
    12241 tggtcttcct ggcttcggtg tagaatggaa cgaagccatc agcggtgatt acggcggcca
    12301 gtgcatgaaa gactacttca ctgccattga cgaaatggcc aaggaacctt tcgtcgacaa
    12361 agaccgcctg ggttgcgtag gtgccagctt cggaggcttc tccgtatatt ggcttgccgg
    12421 acaccatgac aaacgcttca aggcattcat cgcacacgac ggtatcttca acatggaaat
    12481 gcaatatctg gaaacggaag agaaatggtt tgccaactgg gatatgggcg gcgcttattg
    12541 ggaaaagaac aacgctacgg cacaacgcac tttcgccaac tccccgcacc tcttcgtcga
    12601 caaatgggac acccctatcc tctgcatcca cggagagaag gacttccgca tccttgccaa
    12661 ccaggcaatg gccgccttcg atgcagccgt gatgcgtggc gttcctgccg aactgcttat
    12721 ctatccggac gaaaaccact gggtactgaa acctcagaat ggcgtgctgt ggcaacgtac
    12781 cttctttgaa tggctggaca aatggttgaa gccggctaag taaagcccct caaaaacgat
    12841 aaaaacaaat agtcccggat tctttgtcaa gaatccggga ctatttgttt ttattgtaca
    12901 ccgcccgatt cattttttat gactataatt tgggcagttc aaataaagtc aatacatttg
    12961 ctttatgcac actccgaaga agtgtaaaca atatgtccta atataacccg ataaaagatg
    13021 aatgaaaatt ggcctgagat tgtggaaaca ctgataccgt attttgaaac aaattcggta
    13081 gaaggtgact accagcggga aatagagaac tgcttgaaat ttcttggatg gaagaagacc
    13141 aatggaacaa tggtatccca atatacatta ccgataggca atagcaactc catacgcccg
    13201 gacattgtac tttggcgaaa gaacgagcat gacacacaat cccccgtact ccctattgaa
    13261 ataaagcgtc cgtctaatat acgaaatgaa agacaagaaa atcaactgat gtcgt
//
