LOCUS       c00047_gnlPro..        13222 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JKOJAHPC_47.
ACCESSION   c00047_gnlPro..
VERSION     c00047_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 07:32:07
            Original ID  :: gnl|Prokka|JKOJAHPC_47
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13222
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13222
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:3222]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..3222
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13222
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13222
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(3..500)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 76.1; E-value: 6.7e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_1"
                     /sec_met_domain="Fer2_3 (E-value: 2.3e-24, bitscore: 76.1,
                     seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKTLNLTLKVWRQENREAKGRIETYAAKDIPVDASFLEMLDIVN
                     EGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPERQVTTCQLHMRKFKDGDTVWIE
                     PFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAPNANNIAVEKVKADAAFDAAAC
                     IGW"
     CDS             complement(541..2499)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_2"
                     /sec_met_domain="FAD_binding_2 (E-value: 1.4e-54, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 4e-38, bitscore:
                     120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             complement(2521..3222)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg47_3"
                     /sec_met_domain="SucD_FumR (E-value: 8.7e-14, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             3423..3695
                     /locus_tag="ctg47_4"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             3728..4513
                     /locus_tag="ctg47_5"
                     /transl_table=11
                     /translation="MVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSADGFRDYFVQLT
                     ECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLGIGEIGLNRNT
                     SHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLDPCRVLVDHCE
                     EHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADWGDSDPLALTA
                     LACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(4547..4780)
                     /locus_tag="ctg47_6"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPD
                     EFLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(5206..5913)
                     /locus_tag="ctg47_7"
                     /transl_table=11
                     /translation="MKKLLSTLILSAGMSLSATANTTLLDSSIVGYSDFTSQTADFGTL
                     KDSVSITSDDSNLTLSGITFNGYGTNNRDVMSVTMVLDLSKINTPETYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYSGPVVDTPLGMEGSLTISVVTGDLGTRIYFGDSATYYS
                     NSGLKFGNQQIDQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             6208..6948
                     /locus_tag="ctg47_8"
                     /transl_table=11
                     /translation="MKKTLTFLIAMGSFAVSSEAATVFNYYTPGTDNYNSTIHGFYLGL
                     GSSSLAPSDSSSPSSLSGEIRLDSFTLRGAANNLGANVTYGFLVLNGSDNSVIGWSTNT
                     GTTAAGINLTFSFSSLDGSPLLLDAALTYRFLAVSQSVMDLMQDTSKTYLYAAGGTAAP
                     TANTEGDTVTISGGLTAPGIRGHYDAEGAPGDSVVITGANGTNTFSLLSPIFTEIRGEM
                     VPEPATVSLGLLGLAALMMRRLRA"
     CDS             complement(7166..7300)
                     /locus_tag="ctg47_9"
                     /transl_table=11
                     /translation="MYAAALQVCELQRGSLSGLKGHYVKAAVYHMDEKRAAEFDGISR"
     CDS             complement(7412..7612)
                     /locus_tag="ctg47_10"
                     /transl_table=11
                     /translation="MTIALRTEQSSDHAETEHVTREAFWNYFVPGCHEHYLLHIMRVSP
                     SFIPELDAVAVHGSRIVGKHR"
     CDS             complement(7626..8831)
                     /locus_tag="ctg47_11"
                     /transl_table=11
                     /translation="MRGIFLVSCFLGGSALLAGCREENNSPRPATEDAARITSARQWGE
                     SRSALQKRELDRAAGPALPIPDDLPSRELVGTTRQIHQLIEASGNPARFESYTETVPVA
                     EASLRMVAIPGGTFLMGSPAEEPHRKPDEGPQHKVSISPFWISETEIPWELYTAFMENG
                     RPRAKDGQLLEEQPDDELWDSVTQPTAPYTAMNLGMGHGYEHGLPAISMSHHAASKFCE
                     WLSAQTGHYYRLPTEAEWEYACRAGSPGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSK
                     KPNKWGLRDMHGNVAEWVLDSYVPDAYGKRSGLPAKDPLVIIPSAPHIVRGGSWEDDPD
                     SLRSAARRASTPAWNRQDPQNPKSIWYLTDGGMIGFRVVRPMNIPDIMTMHRLWNFSKG
                     EP"
     CDS             complement(8855..9784)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg47_12"
                     /sec_met_domain="adh_short_C2 (E-value: 1.7e-75, bitscore:
                     244.0, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTGRPPVHSGKMKRPDSSPPPRFSPLFFHSRHAPSPYGFLRGQV
                     HFKLAGTVKNGFTVGSMQKLAGKTAIVTGAGRGIGNAVARRFASEGARVILISRSPSSC
                     GGAAEEINKEFPDSCKAYPCDVADYAAVQETMAAILKDFPQIDILVNNAGITRDSLMLR
                     MKEEDWDAVLDTNLKSAFNTVKALQRVLMKSPAGRIINMSSVIGLVGNIGQANYAASKA
                     GLIGFTKSLAQEFAPRKVTCNAIAPGFISTEMSNAIPDNLKEEIVKKIPLKEQGSVEDI
                     AALTAFLASDDARYITGQVIACDGGMTM"
     CDS             complement(9729..10247)
                     /locus_tag="ctg47_13"
                     /transl_table=11
                     /translation="MKAFLVPLLYSALLSGASLAFGETAAGTAFPAAAAPAEKIPSAES
                     LINQAFSFAINIQQTLAGVQDKESVDNAVKTLQDIQKDIRHFLQLQDKLNDAEKEKEDA
                     LIEKMEKRMEMLDNRCRQEGKRLFEARYYGSAALKDILENSDEFSDLVEPDEDGAPPGA
                     LRENEEAGQ"
     CDS             complement(10311..11921)
                     /locus_tag="ctg47_14"
                     /transl_table=11
                     /translation="MLTIKNLTKSHAGRTLFRETEMTINWGERVALVGPNGAGKSTLFR
                     MILGEDTPDEGSISMDEYAIVGYLPQEASEPKDETVLEIALGITPEMEQAIHTIRTAEN
                     ANKTDTPEYAEAIDTFNAANGYQLEPKAKKILKGLAFRESDFHRPAREMSGGWIMRAYL
                     AKLLVLEPDLLMLDEPTNHLDLLSLLWLQRYLKNYPGAILMISHDRDFMDELVESVYDI
                     DNEELVEYRGNYSDFLQQKDVRFEQLQAAYRNQQKEIAHIQEFIDRFRSINSKAGQVQS
                     RIKQLEKMKIIQKPVARRKVFKFNFPQPPRSTQKVIELEKVCQSYGDRRVYENLDLLVE
                     RGERTVLVGPNGAGKSTLLKILAGIIPIDSGQRTPGTTTRIGYFSQARTENLNPENTVL
                     EEIMKCSAEIREEEARSILGSFLFRRLDVEKRVSVLSGGEKSRLSLVKFLVDPPNLLLM
                     DEPTTHLDLLSVEALVQALKHYEGTLVFISHDVHFIRSLAQKTLHVNRGTITAYAGGYD
                     YYLEKSGILDDEKGGITAE"
     CDS             12044..12751
                     /locus_tag="ctg47_15"
                     /transl_table=11
                     /translation="MPTTQTFRLLLAAALLCGWSSCCTPPAEDYIQQPYVQQQMSGLAN
                     AFLALLPPDQASLPAAGAEARWLADTAVVQSAAIARDNRTVLFGWLNNILVNSNLRDRG
                     LCWQVQQDLYRDLRRRPVKYFRIGLTIRDRGTGREHSCVYVNAVGKGLQGSIVLDAWKN
                     CGHLVTLTQKDREGGKWEEDWREPFVSKAFPEGHSYGMEHHLVWPGWARKRPMLVQRIF
                     QSDQQNEAKAAAE"
     CDS             complement(12961..13089)
                     /locus_tag="ctg47_16"
                     /transl_table=11
                     /translation="MKNIAILAIAGAACLVASCSQQQQQQQTTAPAPAPVVQAKGK"
ORIGIN
        1 ccccagccga tgcaggcggc cgcgtcaaag gcggcgtccg ccttcacttt ttccacggcg
       61 atgttgttgg cgttcggcgc ggaaccggta cgcacgtcaa tatagcctcc ggcggcgatg
      121 atgcggtcca gggcggagcg gtccaccatc aggtcccgca ggattgggaa agccttcgcg
      181 cggaagggtt caatccagac ggtatcgccg tccttgaact tgcgcatgtg aagctggcaa
      241 gtggtcacct ggcgttccgg cccgtgggga atgccgttga tggtcaggga gcacatgccg
      301 cagatgcctt cccggcagtc gtggtcaaaa tggatgggtt ccttgccttc cttgaccagg
      361 ccttcattga cgatgtccag catttccagg aaggaggcgt ccaccggaat gtccttggcg
      421 gcataggtct caatgcggcc cttggcttcc cggttttcct ggcgccagac cttgagagtg
      481 agattgagtg ttttagccat gttataatct ttcttttgag tgttaatgta ttggctatct
      541 ttacttgtag ctgcggatgg caaggtgcac gttctcgaag gtcagcggtt ccttgtggag
      601 aacaggcagg ctgtccacgc cagtgtattc ccaggcggct acataggcgt attcatcgtc
      661 gttgcgcttg gcttcgccgt ccggcagctg gtattccacg cggaagtggg cgccgcagga
      721 ttcctggcgg ttcagggcgt catagcagag cagctgggcg aattccagga agtcggccac
      781 gcggcaggct ttttccagtt ccgcgttgat gccgtccgcc gtgccggtta cgcgcacgtt
      841 ttcccagaat tccttgcgga gctggggaat gcgttcaatg gcgtgggtca ggctttcttc
      901 cgtgcgggcc atgccgcagt cttcccacat gatgaggccc agttcccggt ggaaggagtc
      961 caccgtcttg gtgcccttca cattcaggag cttgttgatg cgttccttca cttcgtcttc
     1021 cgcagccttg aattccgggg cggcggtggt gacggcgccg ggcttggtgg tcgtcaggta
     1081 agcgggcaac gtggcgggaa tgacgaagta gccgtcagac aggccctgca tcagggcgga
     1141 ggctcccagg cggttggcgc cgtggtcgga gaagttggct tcaccgagga cgtgcagccc
     1201 cttcacgttg gacatgaggt tgtagtccac ccacaggccg cccatggtgt agtgggaggc
     1261 ggggtagatc atcatgggcg tttcatgggg gtcgtcgtcc gtgatttctt cgtacatgtc
     1321 aaacagattg ccgtattggc cgtcaatcca ttcgcggccc atgcgcttga tttcatccgc
     1381 aaaatccagg aagacgccct tgccggtgac ggccacgccg cggccgtcgt cgcaggcttc
     1441 cttggcggcg cgggaggaaa tgtcgcgcgg agccaggttg ccgaaggagg gatacttgcg
     1501 ttccaggtag tagtcccgtt cttcttcggg aacatcggaa ggcttgattt cctttttacg
     1561 gattttttct gcggtttcac gggacttggg cacccagatg cggccactgt tgcggaggga
     1621 ttccgacatc agcgtcagtt tggactggta gtcgcccttg accggaatgc aggtggggtg
     1681 gatttgcgtg aagcaggggt tggcgaagaa ggcaccgcgc ttgtaggcct tgtaggcggc
     1741 agtgacgttg cagcccatcg cgttggtgga caggaagaac acgttgccgt agccgcccgt
     1801 gcagagcagg acggtatccc ctgcgtagga tttgatttcg ccggtaacca gattgcgggt
     1861 gacgatgccc ttggcttcgc cgtccaccag caccagatcc atcatttcat ggcgggagaa
     1921 catttcaatg tgtcccttgg ccacttcctt ttccagggcc tggtaggcac ccagcaggag
     1981 ctgctggccc gtctgtccgc gtgcgtagaa ggttcgcttg agctgggcgc cgccgaagga
     2041 gcggttgtcc agcaggccgc cgtattcacg gccgaaggga acgccctggg ccacacactg
     2101 gtcaatgatg ttggaggaga cttccgccag acggtagaca ttggcttcac gggcgcggaa
     2161 gtcgccgcct ttaacggtgt cgtaaaacag gcggtaaacg gagtcgccgt cgttctggta
     2221 gttcttggct gcgttaatgc cgccctgggc cgcaatggag tgggcgcggc gggggctgtc
     2281 ctggtagcag aagcatttga cgttgtagcc aagttcggca agcgtggcgg cagcggaggc
     2341 gccagccagg ccggaaccta ccacaagcac cgtgtacttg cgcttgttgt tcggattgat
     2401 cagtttggac tcaagtttgt acttggacca tttgtcctga atagggccgg agggaatttt
     2461 ggcatccggc atccagtcgc ttacgggaaa attaatcatg actttgagag gagttgatgg
     2521 ttatttgatg atacccagaa gaaccgagac cggcacggag atgaagccca ggcagataat
     2581 cgcgccgtag gcgatggcga taaagttgta gaagggccgg attttgcggg aatcgacgcc
     2641 cacagtctgg aagatggact gtaccccgtg gcgtagatgg ctgaacagca tcagaacggc
     2701 caggatgtag aaggcggagc accatacgtt ggagaatccg gtcacgatca tcttgtacac
     2761 gtcaaaggtt tccaccgtac cgtcggaaat aaaggtggtg aactgggcgg ggtcgtatcc
     2821 cacgcgcagg gtgtactggt acaggtggta gatcaggaac accaggacgg tcaaaccggt
     2881 atagatcatg tagcgggagg agagcgttgc cttaatggtg ttcttgaaca cgtagggttc
     2941 gcgggccgca tggttttcca gcttcagctg gatggtcagc cagacgtgga tgatgaagat
     3001 caccgcaagc cccgcgcgga ttccccagag ggctgcttcc ggcatggagt gcaggccgtg
     3061 ggcgtaggtg ttgatccatt cagggcctcc gaagatgaga aggttgcctg ccaggtgtcc
     3121 cgcaaggaac aagaccaaac ataaccccgt cagagccaca atgattttgc ggccgatgga
     3181 ggatgtcacg aatgtacata tggtttttac tagtgcattc ataggcgctc taatgaaata
     3241 aatgcgtctt cacaggatgc ccggttcaag cccggatggc aagcctcttc ttgaatttcc
     3301 ggcgcttttc ggatttttga aaaaccgggg aaagaggttg ctgtttatca gtttggaatg
     3361 gttatcattt tgttgcctgt tccggcttga cgaggctttc cgcataggcg tatcgtctgt
     3421 gcatgaaaag aagtaaaaag gaggtgctgg acgcggattt cgcagcggcg cgcgccggcg
     3481 ttctggatgt ggccgcattt ctggaccggg tggaccgcgg ggaaggggag gcggatttcc
     3541 gctaccatgc cctgatggat gttcttcccc tcttgtccgc atccggcccc ggacgcgtcc
     3601 gggccattct ggaagccctt tcctacaggg atgacaccgt gccggaaacc gccgcagcca
     3661 aagcggcctg cggagccccg aacctcagca aataagaatg atggctttca tagaacctca
     3721 tatacatatg gtgtgccgca ccacggacga ataccgggcc atggcgcagg ccggctgcct
     3781 ggcggtaggg gaaccggcgt tctgggccgg ttacgaccgt tcgtccgcgg acggtttccg
     3841 ggattatttc gtacagctta cggaatgcga acccgccagg gcggccaagt tcggcatgga
     3901 ccattacaca tggctgtgca tcaatcccaa ggaggcgcag gacgtggctt tcgcgcggga
     3961 tgtgatgaaa ctgattccgg agttcattga ccggcccaat gtcctcggca tcggggaaat
     4021 agggctgaac cggaatactt cccatgaaat gactattttt gaagagcatc tggatctggc
     4081 ggtgcgcctc aaccagcttg tgctgattca cactccccat ctggaagaca agcttaaggg
     4141 gaccgtaatg attctttccg ccctgaaaaa ccgtccggat ctggaccctt gccgcgtgct
     4201 ggtggatcac tgtgaggaac ataccttccc gctggtgaag gaggccggtt actgggccgg
     4261 gctgaccctt tatcccacca gtaagctgaa tcccaagcgg gcggcggata ttctggaatt
     4321 gtacggaatg gaccgtgtct gggccaattc cgcggcggac tggggggatt ccgatcccct
     4381 ggcgctgacg gccctggcct gcgagctgcg caggcgcggt ttttcccggc aggaaacgga
     4441 acgtcttctc ctggaaaatc cggagacatt catgggacag tccccgaagt tccggaaagt
     4501 gtcgtcccgc taattccgcc cgaggcgcgg cggagggtac ggccctctag tccccgtccg
     4561 ggaaaaagac ggtgaggacg gcgcccagga tgaccgccgc gtcatccaga aggcccagcc
     4621 tgccgattcc gtcaaacagg aattcgtcgg gagtcaggat gtaggcgccg gcggcggcca
     4681 gaaggcatat attccgtttg ttgaaaaaac gcggttctcc ttttctgctt ttgaaatacc
     4741 ggaacaggcg cagtagcagc tgctgttttt gaaggttcat ggacgggaac gggggataaa
     4801 ggttcaagct cagccatttt cccactcctt ttccctgttt cggggaagga gtctgttgcc
     4861 gacggacgga accgcagcga tccggaccgt gcggggaaat ggattgctga aaggatgggc
     4921 tgttccggat gctgagggaa gccgggcttt gcatgctccg gttccggctg tcccggcatg
     4981 ggaaaaaggg gcgtgtacgg aagtggggcg gggccggaag ctcttgaaat gaccctaccg
     5041 ggggagactg aatgctattt ttccgtcaag tgctggccgt gaggttgccg cagcaaatgg
     5101 aagcttttcc cctctgtttt ttcggcagat gtttgaacgg ataaggaaaa ggccggctca
     5161 cgattttgtg agccggcctt tnnnnnnnnn ncggacggta caggcttatg ccctgcggcg
     5221 gcgcatcatc agcgcggcca gtcccagcag gcccagggaa gccgtggcgg gttccggaat
     5281 gctggcgatt tcactcatca gttgaccaac ttgttcctgg gaaaggaggg agtcgtggat
     5341 gtagagctgt tcgatggatt cagccagtcc tgcgtccatg agaatctgat caatttgctg
     5401 gttgccgaat ttcaggccgc tgttggaata gtacgtagcg ctgtcgccaa aatagatgcg
     5461 ggtgccaaga tctccggtga ctacggaaat ggtcagggac ccttccatgc ccagcggggt
     5521 gtcaacgacg ggcccgctgt atgaggtgtt gttccataat ccctggagtt tccggtccgt
     5581 gttcaggccc acgccccagc ttacactgct gtttttggcg ttaaacagag cggtataggt
     5641 ctccggagtg ttgattttgg acagatcaag aaccattgtc acagacataa cgtcgcggtt
     5701 gttggtaccg tatccgttga aggttatccc ggataacgtc agattgctgt cgtcagacgt
     5761 gatggaaacg gaatctttca gggtgccgaa atccgccgtt tgggaggtaa agtccgaata
     5821 tcccacgata gagctatcca gcagagtggt attcgcggtg gcgctcaggc tcatgccggc
     5881 cgaaagaatc agggtggata ataatttctt catggtcagt atcttaataa aatgatgcaa
     5941 gattcaatgt atgcacttgc gcttgaataa cgaatttgga atccgcaagc aattaaaaat
     6001 attaagagtt agtatattgt atttataatt cattgaaaat aatgattttt taatatctct
     6061 ggtccttttg tcaagatgac ggggcaatct ttgttattca ttggtttcat gattgatttg
     6121 gcctcttttt cattacttga cggattccaa atccgattgg ggaattccaa attcgctaca
     6181 agttgccatc caaaaggaat aataaatatg aagaaaacac tgacattttt aatcgcgatg
     6241 ggaagctttg ctgtttcctc ggaggcagcg accgttttta attattacac tcccggtacg
     6301 gataattaca atagtaccat ccatgggttt tatcttggcc tggggtcttc ttccctggct
     6361 ccttccgatt cctcttctcc ctcctccctg tccggagaga tcagactgga cagttttacg
     6421 ctgcgcggag ccgccaacaa tttgggcgct aatgtcactt acggcttcct ggtgctgaat
     6481 ggctccgaca attcggtcat cggctggagc accaatacgg gaactactgc agcagggatt
     6541 aatctgacgt tcagtttttc ttccctggat ggttctcccc tgcttcttga cgcggcattg
     6601 acataccgtt tcctggccgt gagccagtcc gtgatggact tgatgcagga tacgtctaaa
     6661 acgtatttat atgctgcggg gggaacagcc gcccctactg ctaacacgga aggagatacc
     6721 gtaacgatca gcggcggatt gactgctccc ggcatccgcg gccattatga cgccgaggga
     6781 gcgcctggtg attctgtcgt tattacggga gccaacggaa ccaatacttt cagcttatta
     6841 tccccgattt tcacggaaat ccgaggggaa atggtgccgg aaccagccac ggtttccctg
     6901 ggcctgctgg gactggccgc gctgatgatg cgccgcctca gggcttgagc ttcctgatgg
     6961 cgaaaaatcg gcggatgaga gctgttcttg cggaacagct cttgtttttt atatccagag
     7021 aggaagaatt gcttatccgt atgcgggatt catgccctcc ggaaggtacg gaatttccgg
     7081 gggcaggggg ccgtatccgg ttttttcggc atggcggcaa tttgctggaa acgtttttga
     7141 gacgcagtac cggaaagctt tttctttacc gggaaatgcc gtcaaattcg gcagcgcgct
     7201 tttcgtccat atggtacacg gcagctttca catagtggcc tttcaggccg gatagggaac
     7261 ccctttgcag ctcacagacc tggagggccg ccgcatacat attattcgcc gtcctattcc
     7321 ccggcgctgg tatttcggaa gaacggcaat gggccccatg cccagcactt catattcttt
     7381 tccatcgtct gccctgatga cggacgttgc atcaacgatg tttcccgacg atgcggctgc
     7441 cgtggacggc gactgcatcc agctccggga tgaaggacgg actgacgcgc atgatatgga
     7501 gcaggtaatg ttcatggcag ccggggacga aatagttcca gaacgcttct ctcgtgacat
     7561 gttccgtttc ggcatggtct gaggattgtt ccgttcttaa tgcaatggtc atgaaaggtt
     7621 gttctttacg gctccccctt ggagaaattc cagaggcggt gcatcgtcat aatgtccgga
     7681 atgttcatgg ggcgcaccac gcggaacccg atcatgcctc cgtccgtcag gtaccagatg
     7741 cttttagggt tttgaggatc ctgacggttc caggcggggg tgctggcgcg gcgcgcagcg
     7801 cttctcaggc tgtccgggtc gtcttcccac gaaccgccgc gaacgatgtg aggggcgctg
     7861 gggatgatga ccaaggggtc tttcgcgggc aagccgctcc gtttgccgta ggcatccgga
     7921 acgtaagagt ccaaaaccca ttccgccaca tttccgtgca tgtcccggag tccccactta
     7981 tttggttttt tagagcctgt tttctggtag cggtcattgg agttgttcca gtaccaggcg
     8041 tactggtcca gagaggcttc cccgtttccg taagaatagg cgccggggga gccggcccgg
     8101 caggcgtatt cccattccgc ctccgtgggc aggcggtagt aatgcccggt ctgggcgctc
     8161 agccattcgc agaatttgct ggcggcgtgg tgggacatgg agatggcggg cagaccgtgt
     8221 tcatagccgt ggcccatgcc caggttcatg gcggtgtagg gggcggtagg ctgcgtaacg
     8281 gagtcccaca gttcgtcatc cggctgttcc tccagaagct ggccgtcctt ggcgcgcgga
     8341 cgcccgtttt ccatgaaggc cgtataaagt tcccagggga tttccgtttc cgagatccag
     8401 aagggggaga tgctcacttt atgctgcgga ccttcgtccg gtttccggtg cggctcttcc
     8461 gcgggactcc ccatgaggaa cgttcctccc ggtatggcga ccatgcgcag ggaagcttcc
     8521 gccacgggaa ccgtttccgt gtaggattca aaacgtgccg gatttccgga agcttcaatg
     8581 agctgatgga tttggcgcgt tgtgccgacc agctcccggg acggcaggtc atccggaatg
     8641 ggaagggcag gaccggcagc gcggtccagt tcccgttttt gcagcgcgga tcggctttct
     8701 ccccactggc gtgcgctggt aatgcgcgcg gcatcttccg tggccgggcg gggggaatta
     8761 ttttcttccc ggcacccggc cagcagggcg cttcctccca gaaagcagga aacaaggaaa
     8821 atgccgcgca tggaatggag aaaaccggaa tgccctacat cgtcatgcct ccgtcgcagg
     8881 caatgacctg cccggtgatg taacgggcat cgtcagaggc aaggaaggcc gtcagggcgg
     8941 cgatatcttc cacggaacct tgttctttca aaggtatttt cttaacgatt tcttccttga
     9001 gattgtcggg aatggcattg gacatttccg tggagatgaa gccgggagca atggcgttgc
     9061 acgtgacttt gcgcggagcg aattcctgag ccagtgattt ggtgaaaccg atgaggcccg
     9121 ccttggaagc ggcgtaattg gcctgaccga tgttgccgac gagaccgatg acggagctca
     9181 tgttgatgat gcgcccggcc ggggatttca tgagaacgcg ctggagggcc ttgaccgtat
     9241 tgaacgcgct tttcaggttg gtgtccagaa cggcatccca gtcttcctct ttcatgcgga
     9301 gcatcaggga gtcccgcgtg atgccggcgt tgttcaccag gatgtcaatc tgcgggaagt
     9361 ctttcaaaat ggcggccatg gtttcctgaa cggccgcgta atccgctacg tcgcaggggt
     9421 aggccttgca ggaatccgga aattccttgt tgatttcttc tgcggccccc ccgcagctgg
     9481 atggactgcg gctgatcagg atgaccctgg ctccttccga agcgaagcgg cgcgcgacgg
     9541 cattgccgat tccgcggccc gcgccggtaa cgatggctgt tttacctgct aacttttgca
     9601 tgctgcccac agtaaacccg tttttcacgg ttccggcaag cttgaaatgg acttggccgc
     9661 gcaggaaccc atacggggaa ggggcgtgcc gggaatgaaa aaagaggggg gagaaacggg
     9721 gcggggggct actgtccggc ctcttcattt tcccggagtg caccgggggg cgccccgtct
     9781 tcatccggtt ctaccaggtc gctgaattca tccgaatttt ccaaaatgtc ctttaaggcg
     9841 gcggaaccgt aatagcgggc ctcaaacagg cgtttgcctt cctgcctgca gcggttgtcc
     9901 agcatttcca ttcgtttttc cattttttct atcaaggcgt cttctttctc cttttccgca
     9961 tcgttcaatt tatcctgaag ctggaggaaa tgccggatgt ccttctgaat gtcctgcagc
    10021 gttttgacgg cgttgtccac gctttccttg tcctgaacgc ctgccaacgt ctgctggata
    10081 ttgatggcaa aggaaaaggc ctggttgatc agggattccg cggaaggaat tttttccgcc
    10141 ggagccgctg ctgcggggaa agccgttccg gcggccgttt caccaaatgc aagagaggct
    10201 ccggacagaa gcgcagaata taagagagga acaagaaaag ccttcatcct gttcttttaa
    10261 ggcaggatga aatccacggc aaggaaaaag gggaaactga aaaaagagcc ttattccgcc
    10321 gtgatgccgc ctttttcatc gtccagaatg cctgactttt ccagatagta gtcatatcca
    10381 cctgcgtagg cggtgatggt cccccggttc acatgcaggg ttttttgtgc cagggaacgg
    10441 atgaagtgca catcgtggga gatgaagacc agtgttcctt cataatgctt cagagcctgc
    10501 accagggctt ctacggacaa aaggtccagg tgggtggtcg gctcgtccat cagcaggagg
    10561 ttgggcggat ccaccaggaa tttgaccagg ctgagccgcg atttttcccc gccggaaaga
    10621 acgctgacgc gtttttccac atccagcctc cggaacagga aggaacccag gatggaacgc
    10681 gcttcttcct cccggatttc agcgctgcat ttcatgattt cctccagcac ggtattttcc
    10741 ggattcaggt tttccgttcg cgcctgggag aagtagccga tgcgcgtcgt ggtaccggga
    10801 gtgcgttgtc cggagtcaat ggggatgatg cccgccagga ttttgagaag agtggatttg
    10861 cccgcgccgt tcgggcctac aagaacagtg cgctccccgc gttctaccag caggtccagg
    10921 ttttcataaa ccctgcggtc gccataggat tggcagactt tttccagctc aatgactttc
    10981 tgggtgctgc gcggaggctg ggggaagttg aatttaaata ctttcctgcg ggctaccggt
    11041 ttttgaatga ttttcatctt ttccagctgc ttgatgcggc tctggacttg cccggctttg
    11101 gaattgatgg agcggaaacg gtcaataaat tcctgaatgt gcgctatttc cttctgctgg
    11161 ttgcggtagg ccgcctgaag ctgctcgaag cgcacgtcct tttgttggag gaagtccgag
    11221 taattgccgc ggtattccac cagttcttcg ttgtcgatgt cgtacacgct ttccaccagc
    11281 tcatccatga aatcccggtc gtgggaaatc atcaggatgg ctccggggta gtttttcagg
    11341 tatcgctgga gccacagcag ggacaggagg tccaggtggt tggtaggttc gtccagcatc
    11401 aggaggtccg gctccaggac aaggagcttg gccaggtacg cgcgcatgat ccagccgccg
    11461 gacatttccc gggcggggcg gtggaagtcg ctttcccgaa aggccagccc tttgagaatt
    11521 tttttggctt tgggctccag ctggtaaccg ttggcggcgt tgaaggtgtc aatggcttcc
    11581 gcgtattccg gcgtatccgt tttgttggcg ttttccgccg tccggatggt gtggatggcc
    11641 tgttccattt ccggcgtgat gcccagggcg atttccagaa cggtttcatc cttcggttcg
    11701 ctggcttcct ggggaagata gcccacgatg gcgtattcat ccatgctgat ggagccttcg
    11761 tccggcgtgt cttctcccag aatcatgcgg aacagggtgg atttgcctgc tccgttgggg
    11821 ccaaccagag ccacccgttc cccccagtta atggtcattt ccgtttccct gaacaaggtc
    11881 cgtccggcgt gggattttgt gagatttttg atcgtcagca tggtgaagag aggatgtatt
    11941 ctaccgggat ggaaagggga aggcaagagc cgtcagggcg gaggcaggca tttttgaaag
    12001 ctttactgga tttttacgcg tagtctgcta gccttggcgc gccatgccga ccacgcagac
    12061 attcaggctt ttgcttgctg ccgccctttt gtgcggatgg agttcctgct gtactcctcc
    12121 ggcggaggat tatatacaac aaccttacgt gcagcagcaa atgtccgggc tggctaatgc
    12181 cttcctggcg ctgctgccgc cggatcaggc ctctcttccc gctgccggag cggaggccag
    12241 gtggctggcg gacacggccg tggtccagtc cgcagcgatt gcccgggaca acaggactgt
    12301 gctgtttggc tggctgaaca atattctggt caattccaac ctgcgcgaca gggggctgtg
    12361 ctggcaggtc cagcaggatt tgtaccggga cctgcgccgc cgccccgtga agtatttccg
    12421 catagggctg acgattcgag accgtggaac gggcagggag cacagttgcg tgtatgtcaa
    12481 tgccgtgggg aagggattgc agggctccat tgttctggat gcctggaaga actgcgggca
    12541 tctggtgacg ctgacccaga aggaccggga aggcggcaaa tgggaggagg actggcggga
    12601 accatttgtt tccaaggcct ttccggaggg ccattcctac ggcatggaac atcacctggt
    12661 ctggcccggg tgggccagga aacgccccat gctggttcag cggatatttc agtccgatca
    12721 gcagaatgag gcgaaggcgg ccgctgaata aaggggaagc ctgatccggc aggaaccggc
    12781 acacggtgct gcgccgcggc ggtttgcggt atccgccgtt tttaaggaaa atcccggcga
    12841 atcggcaaat ggcggaggga atccggactc agggcaaata aaaacgcact cagtgcgtac
    12901 accgagtgcg gattaattgg ataatttgct agtgttgcag ggcaaaaccc cgctgcaaac
    12961 ttacttgccc ttggcctgca caaccggagc gggagcagga gcggtggttt gctgttgctg
    13021 ctgctgctgg gagcaagaag cgaccaggca agcggcgccg gcgatggcga ggatagcgat
    13081 gttcttcata attcgaatta aatacagtgt ttgttaacta ctggaacctc cgcatccacg
    13141 gaggtttgct ggcaccaatg taaatggtgg caagtagaaa tcaagagatt ttcttgttcc
    13201 atgtcacggc attacagaaa ag
//
