LOCUS       c00074_gnlPro..        14739 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IABAIMCC_74.
ACCESSION   c00074_gnlPro..
VERSION     c00074_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 07:52:55
            Original ID  :: gnl|Prokka|IABAIMCC_74
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14739
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14739
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[180:5415]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      181..5415
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..14739
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14739
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(181..765)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg74_1"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.2e-64, bitscore:
                     207.3, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIMEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETALGMSAA
                     VAFVLTIATIVTFLIQKYVLDAFDLGYLQTITFILVIAALVQMVEIILKKVSPSLYQAL
                     GVFLPLITTNCCILGVAILVIQKDYDLLTGVVYAFSTALGFGLALTLFAGLREQMSLVS
                     VPKGMQGTPIALITAGLLAMAFMGFSGVVKI"
     CDS             complement(853..1419)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg74_2"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.1e-70, bitscore:
                     227.0, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMNGIIKENPTFVLLLGMCPTLGTTSSAINGMGMGLATMFVLICS
                     NVVISAIKNLIPDMVRIPSFIVVIASFVTLLQMIMQAYVPALYATLGLFIPLIVVNCIV
                     LGRAEAFAAKNNPVASLFDGLGMGLGFTIALTLLGAVREFLGTGKIFNLSILPEEYGML
                     VFVLAPGAFIALGYLIALINSMKKN"
     CDS             complement(1454..2089)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg74_3"
                     /sec_met_domain="FMN_bind (E-value: 2.4e-24, bitscore:
                     75.7, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVLTGVTAISVALLAYVNELTKEPIAQANAKTLSDAVSAVVPG
                     FDNDPIAEKKMQEVNGVQYSVYPATKGGEYIGAAVEAVAMGFGGELKVLVGFDAEGKII
                     DYSLLSHVETPGLGSKAADWFKKGNKGDITGMNPGEAALTVSKDGGKVDAITASTITSR
                     AFLNAVNAAYAAYAGQETADGTTGATQKNVEQPADSAAPEAVDTLSAK"
     CDS             complement(2116..3108)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg74_4"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 2.2e-119,
                     bitscore: 387.9, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKLIVSLSPHVHGGDSVKKNMYGVLIALIPAFLVSLYFFGLGAL
                     IVTATSVAACLFFEWAIGKFLMKKETTTITDGSAIITGVLLAFNLPSNLPIWIIILGAL
                     FAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFPVQMTTWPAVGQLTAYTDATTAATPLA
                     IMKGVINGAPGMSLSDLPGAFDLLIGNNGGCLGEVSALALLLGLFYMLWKKIITWHIPV
                     SILVTVFVFSGIMYLVNPELYVSPVVQLLSGGLMLGAVFMATDYVTSPMSHKGMLIYGV
                     CIGLLTVIIRLFGAYPEGMSFAILIMNAFTPLINTYVKPKRFGEVAKKK"
     CDS             complement(3115..4452)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg74_5"
                     /sec_met_domain="Fer4_10 (E-value: 2.1e-09, bitscore: 27.3,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 4.2e-16, bitscore: 48.5,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 1.1e-49, bitscore:
                     158.1, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 5e-30, bitscore: 93.4,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.9e-05, bitscore: 14.0,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIIKAEIPAKAAILLGQHIGAPAK
                     PIVAKGDVVKVGTKIAEPGGFVSAAIHSSVSGKVAKIDTIVDASGYAKPAIFIDVEGDE
                     WEESIDRSETLVKECSLTSEEIVKKIADAGIVGLGGACFPTQVKLCPPPAFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEIMVGVSILMKAVKVNKAFIGIENNKPDAIQLMTKVASS
                     YAGIEVVPLKVQYPQGGEKQLIDAVISRQVTAGALPISTGAVVQNVGTAFAVYQAVQKN
                     KPLFERVITVTGKSLAKPSNFLARIGTPMKQLIEACGGLPEDTGKIIGGGPMMGKALVN
                     TDVPTAKGSSGILIMNEKEAKRGEVQPCIRCAKCVGACPMGLEPYLLATVSAHGDFERV
                     EKEDIMSCIECGSCQFTCPSNRPMLDYIRLGKGKVGAMIRARQAKK"
     CDS             complement(4513..5415)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 37.6; E-value:
                     8.3e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg74_6"
                     /sec_met_domain="Fer4_7 (E-value: 1.7e-12, bitscore: 37.6,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 9.8e-10, bitscore: 27.9,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 5.3e-09, bitscore: 25.8,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 5.5e-09, bitscore: 25.8,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 1.2e-11, bitscore: 34.0,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6.3e-06, bitscore: 16.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNVILIAVISLGVIALVSAAILYVASKKFAVYEDPRIAQVAEVLP
                     QANCGGCGYPGCSGFADACVKAGSLDGKLCPVGGQPVMTKIAEILGLDAAAAEPMVAVV
                     RCNGTCANRPRVNQYDGAKSCAIAASLYGGETGCGYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEEKCTACGACAKACPKSIIEIRPQGKKSRRVYVQCVNKDKGAVARKACTVACI
                     GCGKCVKVCPFEAITLENNLAYIDPNKCKSCRKCEEACPQNTIIALNFPPRKPKADDAA
                     PQVKVAAPKAEVETPKAEV"
     CDS             complement(5453..5872)
                     /locus_tag="ctg74_7"
                     /transl_table=11
                     /translation="MANTIKHQGIVENINGSHLQVRIIQTSACASCSVKGHCTSADTKE
                     KLVDVADADAASYQPGDRVWVTGELSMGVMAVLFAFIFPFLILIISLFVFMAIWNDELR
                     SALCSLALLVPYYYILWLNKSRMGKKFSFSVRPMN"
     CDS             complement(6103..7503)
                     /locus_tag="ctg74_8"
                     /transl_table=11
                     /translation="MISSSVMAQNTLDTASKNSGQETTAKADTLPDIMKEYMILKLKPE
                     GMGYRLDTVSILYERYIGVLDYLNDPTTPERYIPSNPNYYRLFLPLTYYYAPMRRLSKV
                     DWHFQVPDTVPALTREMLPFDTLSFTSKDRANKLVDRTLLNTYVNCPNLVVMTEKEVMK
                     GKIFKDNIEKEVSSKPSVVKLFAQENMVGVKEEADVIIHKPNWWVTGGNGSLQITQNYI
                     SDNWYKGGESTNAVLANLQLFANYNDREKVQWENLLDAKLGFSSAPSDEFHNYLVSTDQ
                     LRLYSKLGIQAASKWYYTITTEFKTQFCNGYKANSEELVSAFFAPADWSSSIGMDYKLK
                     KQKFSLSVFMAPLTYMLRYVGNKGVNEVSFGLDEGKCVKHNFGSQIQPTLSWTIIPSIT
                     LDSRLDFQTSYEWTRIEWENTVNFVLNRYLSTKLYVHARYDDSAKPTEGDSYFQVKELL
                     SFGINYKW"
     CDS             complement(7575..7781)
                     /locus_tag="ctg74_9"
                     /transl_table=11
                     /translation="MPRAYTACRSRCILLPSVHVELKKRKIIKKRGSRESFDETIIKKY
                     DFIEESPSCLFLMAFLCFLNILS"
     CDS             7813..9432
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg74_10"
                     /sec_met_domain="GATase (E-value: 7.7e-55, bitscore: 175.4,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VGETKYIFVTGGVASSLGKGIISSSIGKLLQARGYKVTIQKFDPY
                     INIDPGTLNPYEHGECYVTVDGHEADLDLGHYERFLGIQTTKANNITTGRIYKSVIDKE
                     RRGDYLGKTIQVIPHITDEIKRNVKLLGNKYKFDFVITEIGGTVGDIESLPYLESIRQL
                     KWELGKDALCVHLTYVPYLAAAGELKTKPTQHSVKELQSAGIQPDVLVLRTEHELSTTL
                     RKKVALFCNVDENAVVQSIDAPTIYEVPILMQSQGLDVTILKKMGLPVGDTPGLGPWRA
                     FLERRHKAEETAPLHIALVGKYDLQDAYKSIREALSQAGTYNDRKVSVDFVNSEKLTDE
                     NVAEALKGMAGVLIGPGFGERGVAGKFVAIKYARTHDIPTFGICLGMQCIAIEFARNVL
                     GYADANSREMDEKTPHNVIDIMEEQKSITNMGGTMRLGAYECVLQKGSKAYEAYGTEHI
                     QERHRHRYEFNNSFKDAYEAAGMKCVGINPESDLVEIVEIPALKWFVGTQFHPEYSSTV
                     LHPHPLFVAFVKAAIENENEKK"
     CDS             9464..11317
                     /locus_tag="ctg74_11"
                     /transl_table=11
                     /translation="MDKNTITGLVLIAILLVGFSFLSRPSQEQLEAQQRYYDSIAQVQQ
                     READLKAKAEAALANESGAEASVDSTALFFDARQGTNSQVTIQNNLAEITVDTKGGRIA
                     SATLKEYMGQDKTTPVTLFSGNDASMNFLFYNKKETIQTEDYYFTAVNRTDSTVTMRLS
                     ADSNSYIDFTYSMHNDTYLIDFTIQAVNMEGKLAATNNYVDIEWSQRARQIEKGYTYEN
                     RLAELTYKITGEGTDYLSANKNDEKEVPERLDWIAFKNQFFSSVFLADADFEKTKLSSK
                     METQGSGYIKDYSAEMSTKFDPAGKEPTQLFFYFGPNHYKTLTALDKGRDDKWELNRLV
                     YLGWPLIRWINKWFTINIFDWLSSWGLSMGIVLLFMTLIVKAVVFPATWKTYMSSAKMR
                     VLKPKIDEINKKYPKQEDAMKKQQEVMGLYSQYGVSPMGGCLPMLIQFPILMALFMFVP
                     SAIELRQQSFLWADDLSTYDAFINFPFHIPFLGSHLSLFCLLMTVTNILNTKYMMQQQD
                     TGANPQMAAMKWMSYLMPVMFLFILNDYPSGLNYYYFISTLVSVVTTLIMRKTTNEEAL
                     LAQLEANKKDPKKMKKTGFAARLEAMQKQQEQMMKEKQNKK"
     CDS             11420..12751
                     /locus_tag="ctg74_12"
                     /transl_table=11
                     /translation="MQTKYTYKQIWLIAYPILISLLMEQMIGMTDTAFLGRVGEVELGA
                     SAIAGVFYMVIFMVAFGFSIGAQILIARRNGERQYKEIGDLFYQGIYFQVGMATVMFLL
                     SYCFSPIILKRIVASEHIYEAATSYLHWRVFGAFFSFSAVMFRAFFLGTTQTKTLTLNS
                     IVMVLSNVVFNYILIFGKFGFPALGIAGAAIGSSLAELVSLLFFILYTRSRIDCCKYGL
                     DRIPKFRLDVLKRMLNVSFWTMIQNFFSLSTWFLFFLYVEHLGERSLAVTNIVRNVSGI
                     LFMVLMAFASTCGSLVSNLIGAGHSDCVAGTIRQHVRIAYVFVLPLALLFAVFPKLILG
                     IYTDIPDLQDAAVHSLWVMCSTYLFLVPANVYFQAVSGTGNTRTAWGLEMATLVIYTAY
                     ITYIILILQLDVAICWTSEMVYSSFILIFCWLYIKRGNWQGRKI"
     CDS             12813..14738
                     /locus_tag="ctg74_13"
                     /transl_table=11
                     /translation="MSAAMTLASCGGTKDAGQQQDAATLIQRSDIKIEGKRMTPEALWA
                     MGRIGSVAVSPDEKQIAYTVSYYSVPQNKSNSEVFVMNADGSDNTQITHDAWQEGQPTW
                     FKDGKKLAFLCNESGSSQVWEMNPDGSGRKQLTQYEGDIEGFSFSPDGKKLLFIAQVKT
                     VKSTADKHPDLPKATGIIVTDLMYKHWDEWVTTAPHPFVADFDGNAISNVTDILEGEPY
                     ESPMKPWGGIEQLAWSPSSDKVAYTCRKKTGLAYAISTNSDIYIYDLASKETKNITEEN
                     KGYDTNPQYSPDGKYIAWQSMERDGYEADLNRLFIMNLETGEKRFVSKAFESNVDAFLW
                     NKDSQSIYFIGVWHGETQIYNIDLAGNDKLTRLTDGMYDYASLALCGDKIIAKRHSMSM
                     GDEIYAVNSARNGDAFAEAVQLTTENKQIYDQLEMGKVEARWMKTTDGKQMLTWVIYPP
                     QFDPNKKYPTLLFCEGGPQSPVSQFWSYRWNFQIMAANDYIIVAPNRRGLPGFGVEWNE
                     AISGDYGGQCMKDYFTAIDEMAKEPFVDKDRLGCVGASFGGFSVYWLAGHHDKRFKAFI
                     AHDGIFNMEMQYLETEEKWFANWDMGGAYWEKNNATAQRTFANSPHLFVDKWDTPILCI
                     HGEKDFR"
ORIGIN
        1 tgagaaccaa tataaccggt tccacccgta actaagattt tccctttcat ataaatatag
       61 ataatttagc ttttaggtta tcaatacgcc acaaatgtaa ggaaataaat taataaaaac
      121 agaaaaaggg ggataaattt tagtttatcc cccttccact ttatttccgg tttttcttct
      181 ttaaatcttc acaacccccg aaaagcccat gaatgccatt gccagcagtc cggcagtaat
      241 caaagctatc ggagtaccct gcataccttt cggtacacta accaggctca tttgctcgcg
      301 caggcctgca aacagtgtca gtgccaagcc gaaaccaagt gccgtggaga atgcataaac
      361 cactcccgtc agcaaatcat aatctttttg gataacaagg atagccacac cgagaataca
      421 gcagttggta gtaatcaacg gcaggaacac gcccaaggcc tgatacagag aaggagatac
      481 tttcttcagg ataatctcta ccatctgcac caatgcggca atcaccagga taaaggtaat
      541 agtctgcaaa tagcccaaat caaaagcgtc gagcacatac ttctgaataa ggaatgtcac
      601 gatagtggcg atggtgagca cgaatgccac cgctgccgac atgcccaatg cagtctccac
      661 tttcttggaa actcccaaga acgggcaaat tcccaagaat tgcgacaata cgatgttgtt
      721 tacaaagatt gccgagataa atatcaatat atattccata atcattaaat taagaattaa
      781 aaactaaaaa ttaaaagccc ggcagcctac cgccgatacg ttctcaattt tttcattttt
      841 aatttttcat tattaattct tcttcatact gttgattaaa gcaatgagat agcccaatgc
      901 gatgaatgca cccggagcaa ggacaaatac caacatgccg tattcttcag gaaggatact
      961 caagttgaat atcttgccgg ttcccaggaa ctcacgcacg gcacccagta atgtcagtgc
     1021 aatggtaaag cccaagccca tgcccagacc gtcgaacaag gaagccaccg gattgttttt
     1081 ggcagcaaat gcctcggcac gtcccaatac gatacagttt acaacaatca gtggaatgaa
     1141 caggcccagt gtggcgtaca atgcaggaac gtaagcttgc attatcatct gcaacagtgt
     1201 cacaaatgat gctatgacta caatgaatga agggatacgc accatatcgg gaatcagatt
     1261 cttgatggca gaaatcacca cattggaaca tatcagcacg aacattgtag ccagtcccat
     1321 acccataccg ttaatggcag aggaagtggt acccagtgta ggacacatac ccagcaggag
     1381 tacaaacgta ggattctctt tgataatccc gttcatcata actttaaaat tattcatatc
     1441 ttctactcct ttctcattta gcgctgagtg tatccacagc ttcgggagct gcggaatcag
     1501 caggttgttc aacattcttt tgagtagcgc cggtagtgcc gtcggcagtt tcctgaccgg
     1561 cataggcagc ataagccgca ttcactgcat tcaaaaaagc acgtgaggtg atggtagacg
     1621 ctgtaatggc atctacttta ccaccgtcct tgctcactgt caatgcagct tcacccggat
     1681 tcatgccggt gatgtcacct ttattgcctt tcttgaacca gtcggcagcc ttggaaccca
     1741 accccggagt ttccacatgc gacaacaagg agtagtcgat gattttgcct tcagcatcga
     1801 aaccgaccaa cactttcagc tcaccgccaa aacccatggc aacagcttcc acagcagctc
     1861 cgatatattc tccgcctttg gtggcaggat atacagaata ctgtactccg tttacttcct
     1921 gcatcttctt ctcggcgatg gggtcattgt cgaagcccgg aaccaccgca cttacggcat
     1981 cgctcaaggt ctttgcattg gcctgcgcaa tgggctcctt cgtcaattcg tttacataag
     2041 ccagcaacgc tacggagatt gcggtaacgc ccgtaagtac cagcaacata ttcttcaagg
     2101 atgattctaa ctttttcatt tcttcttcgc tacctcccca aagcgtttag gtttaacata
     2161 ggtgttgatg agcggagtga acgcattcat aatcagaatg gcaaacgaca taccctccgg
     2221 atatgcaccg aacagacgga tgatgacagt cagtaggccg atgcaaacac cataaatcag
     2281 catacctttg tggctcatcg gagaagtcac gtagtccgta gccataaaga cagcacccag
     2341 catcagacca ccggacaaca actgtacgac cggggataca taaagttccg gattgaccag
     2401 atacatgata ccggagaaca cgaataccgt caccagaata gataccggaa tgtgccaggt
     2461 gatgattttc ttccacaaca tgtagaacaa accaagcagc agcgccaagg cactcacctc
     2521 accgagacat cctccattat tacctatcag aaggtcgaaa gctcccggaa ggtcgctcag
     2581 ggacatgccc ggagcaccat tgatgacacc tttcataata gccagcggcg tagcagctgt
     2641 cgtggcatcc gtataggctg tcaactggcc tacagccggc catgtcgtca tctgcacggg
     2701 gaatgaaagc aacaggaaca cacgtcctgc cagtgcaggg ttaaagggat tgcaacccaa
     2761 acctccgaag gacatcttgc ctaccccgat ggcaaacaag gcaccaagga tgataatcca
     2821 gatgggcagg ttggaaggca ggttaaaggc cagcaacaca ccggtaatga tggcagaacc
     2881 gtcggtaatg gttgtggtct cttttttcat gaggaatttg ccgatggccc attcaaagaa
     2941 caagcaggct gctacggaag tggccgtaac aatcagcgca cccagtccga aaaagtaaag
     3001 cgaaacaagg aatgccggaa tcaatgcgat aagcacaccg tacatattct tcttcacgct
     3061 gtcaccgccg tgaacgtggg gcgaaaggga tacgattaat ttattcatac ttcgttattt
     3121 tttagcttga cgtgcacgga tcatcgctcc taccttaccc ttacccaagc ggatataatc
     3181 cagcatcgga cggttggaag gacaagtgaa ctggcatgaa ccgcattcta tacacgacat
     3241 aatgtcttct ttctctactc tttcaaaatc tccgtgggcc gaaacggtag ccagcagata
     3301 cggctccaac cccatcgggc aggctcccac gcacttagca caacggatac aaggctgtac
     3361 ttcgccgcgc ttggcttcct tctcgttcat aatcagaata ccggagcttc ctttggctgt
     3421 cggtacatcc gtatttacca gagctttacc catcatcggg ccaccgccga taatcttgcc
     3481 cgtatcttcg ggcagaccgc cgcaagcttc aatcagctgc ttcatcggcg taccgatacg
     3541 tgccaggaaa ttggacggct ttgccaacga cttaccagtc acggtaatga cacgctcaaa
     3601 cagaggtttg ttcttctgta cggcctggta aacggcaaat gcggtaccca cattctgcac
     3661 cacagctccc gtggagatag gcagcgcacc ggctgtaacc tggcgactga tgacagcatc
     3721 aatcaactgc ttttcaccac cctgcggata ttgtaccttc aagggtacca cctcgatacc
     3781 tgcatagctg gaagcaacct tcgtcatcag ctggatggca tcgggcttgt tgttctcaat
     3841 gccaatgaat gccttgttca cctttaccgc tttcatcaga atggatacac ctaccataat
     3901 ttcttccgca tgttccagca tcagctgatg gtcggcagtc agatacggtt cgcactctac
     3961 ggcgttgatg atgacacact ctgccttgaa tgcaggagga ggacacaact tgacctgcgt
     4021 aggaaagcat gcaccgccca gacctacgat accggcatca gcgattttct tcacgatttc
     4081 ctcggaggtc agactgcatt ccttcaccaa cgtttcggaa cggtcaatgg attcttccca
     4141 ttcatcccct tctacgtcaa tgaatatagc aggcttggcg taaccgctgg catcgacaat
     4201 cgtgtcaatc ttagcgactt tcccgctgac agacgaatga atggctgctg atacaaaacc
     4261 gccgggctcg gcaatcttcg tacccacttt cacaacatca cctttggcaa cgataggctt
     4321 ggcaggagca ccgatgtgct gtcccagcaa gatagcggcc ttggccggaa tctctgcctt
     4381 gatgataggc tgatgtgctg aaagtttatt ttcgtgtgga tggactccac caattgaaaa
     4441 tgtcttcaac atacaattct gtatttttag tcgtttattt actttattaa ttcatacctc
     4501 aacttgggaa gtctaaacct ctgctttggg agtctcaacc tcagctttag gagctgcaac
     4561 ctttacttgg ggagctgcat cgtcagcctt cggtttgcgc ggcgggaagt tgagggcaat
     4621 gattgtgttt tgcggacaag cttcctcgca cttgcgacag gatttgcact tattggggtc
     4681 aatgtaagcc agattgtttt ccagcgtgat agcctcgaac ggacaaacct tcacacactt
     4741 gccgcaaccg atacatgcca cggtacaagc cttgcgtgct acagccccct tgtccttgtt
     4801 tacacactgt acgtaaacac gacgtgattt cttgccttga ggacggattt caatgataga
     4861 tttcggacaa gccttggcac aagctccaca agccgtacac ttttcctcat ccacttcggg
     4921 aagtccggtc tccggattca tgtggatagc atcgaactgg caggcagcca cacagtcgcc
     4981 gcatcccaga cagccataac cacaacccgt ttcaccacca tagagagaag ccgcaatggc
     5041 acaactcttg gcgccatcgt attggttcac acgaggacgg ttggcacaag ttccattaca
     5101 tctcaccacc gcaaccatag gttcggcagc agcggcatcc aagcccagaa tctcggcaat
     5161 ctttgtcatg acgggctgtc cacccaccgg acaaagttta ccatccagcg aacctgcctt
     5221 tacgcaagca tctgcaaatc cgctacaacc ggggtaacca catccaccgc aatttgcctg
     5281 gggaagcacc tctgctacct gggcaatccg cggatcttca tacacggcga atttcttgga
     5341 agccacgtaa agaatagcgg ccgataccag cgctataact cccaatgaaa tcactgcaat
     5401 cagaattaca ttcataaatt agttgtttat taattatttg ttttattatt agttagttca
     5461 tcggtcgtac ggagaatgag aacttcttac ccatccgcga cttgttcagc cacaatatat
     5521 aataataagg tacaagaagt gctagcgaac aaagcgcgga acgcagctcg tcattccaga
     5581 tagccataaa gacaaacagt gagattatca gaataaggaa aggaaatata aaggcaaaca
     5641 gaactgccat cactcccatt gaaagttcgc ccgtcaccca tacacggtcg ccgggctggt
     5701 aggatgcggc atcggcatcg gccacatcga caagtttctc tttcgtatcc gcagaggtac
     5761 aatgtccctt gacactacac gaagcgcatg ctgaagtctg gatgattctc acttggagat
     5821 gagaaccgtt tatgttttcc acaatacctt gatgttttat agtattcgcc attttgcaaa
     5881 gtgtgcatta caaatcgtgg caaatttacg cattatttgt gaactgcaaa cctttcctat
     5941 gtattttctg tgttcgcaaa catgcttttt ctatgttttt atgttttttc acctgccaca
     6001 gactacaaaa agacaaaaaa cagacggtct gtcaagggaa aacagaccgt ctgactaact
     6061 aaaacagata atctgttcac tccgaacaga ccatttgttt atttaccatt tataattgat
     6121 accgaaactg agcaattctt ttacctgaaa atagctgtcc ccttccgtcg gcttggcact
     6181 gtcgtcatag cgggcgtgca catagagctt ggtggaaaga tagcggttca gcacaaagtt
     6241 caccgtgttt tcccattcaa tacgtgtcca ctcataactg gtctggaagt ccaagcggga
     6301 atccagcgtg atggaaggaa tgatggtcca tgaaagtgta ggctgtatct gcgaaccgaa
     6361 gttatgcttc acgcatttgc cctcatcaag accgaaactc acttcattca cccccttatt
     6421 tcctacatag cgcagcatgt acgtcagcgg agccatgaaa acggacaagc tgaatttctg
     6481 cttcttcaac ttgtagtcca taccgatact gctcgaccag tctgccggag caaagaaagc
     6541 cgaaaccagc tcttcactgt tggccttgta gccattgcag aactgggtct taaactcagt
     6601 cgtgatggta taataccact tggacgcagc ctgaataccc agtttactgt acagccggag
     6661 ttggtcggta cttaccagat agttatgaaa ctcgtcggaa ggtgcggagc tgaagcccag
     6721 cttggcatcg agcagatttt cccactgcac cttttcacgg tcattatagt tggcaaacaa
     6781 ttgcaggttg gcaagcacgg cgttagtgct ctcacctccc ttgtaccagt tgtcggagat
     6841 atagttctgg gtaatctgca atgaaccgtt tccacccgtc acccaccagt tgggcttgtg
     6901 gataatcacg tcggcttcct ccttcactcc caccatattc tcttgtgcaa acagtttcac
     6961 gacggacggc ttggaagaaa cctccttctc tatattatcc ttgaatatct tccctttcat
     7021 cacctccttc tcggtcatta caaccagatt gggacaattc acatacgtgt tcagcagcgt
     7081 acggtccacc agtttgttgg ctcggtcctt tgaggtgaaa ctcagtgtgt cgaacggcaa
     7141 catctcgcgc gtcagggcag gcaccgtatc aggcacctgg aaatgccagt ccaccttgga
     7201 aaggcgtctc atgggggcat aataataggt aaggggaagg aacaacctat agtagttcgg
     7261 attggaaggt atataacgct ccggagtcgt ggggtcattc aaataatcca gcactccgat
     7321 atacctttca tataatatgg aaacagtatc cagcctgtac cccatacctt ccggtttcaa
     7381 tttcagaatc atgtattctt tcattatatc cggcaaggtg tcggctttgg cagttgtttc
     7441 ctgtccactg ttcttcgagg cggtatccag cgtattctgt gccatcaccg acgaagaaat
     7501 catcgtagca attaaccaaa atgcaatgtg tctattcttc ataatgccct aaagtctatg
     7561 tttcgagcgc aaatttagct taaaatgttt agaaaacata gaaaagccat aagaaaaagg
     7621 caagaaggac tttcttcgat gaaatcgtat tttttaataa ttgtttcatc gaaactttct
     7681 ctacttcctc ttttttttat aattttgcgc tttttaagtt ctacgtgtac tgacgggagc
     7741 agtatgcacc ttgaacgaca agccgtatag gctcttggca ttagattaaa caattaataa
     7801 aataatatag ttgtgggaga aacaaagtat attttcgtca ccggtggtgt tgcctcttca
     7861 ttaggtaaag gtatcatctc atcctccatc ggtaaattgc tgcaagcaag aggttacaag
     7921 gtaaccatcc agaagtttga cccgtacatc aacatcgacc cgggtacact gaacccttat
     7981 gaacacggcg aatgctacgt taccgtggat ggccacgaag ccgacctcga tttgggccat
     8041 tacgaacgct tcctgggcat ccagaccacc aaggccaaca atatcacgac cggacgcatc
     8101 tacaaaagcg tcatcgacaa agagcgccgg ggtgactatc tgggaaagac catccaggtt
     8161 attccccata ttacagacga aatcaagcgt aatgtaaaac tgctgggaaa caaatacaaa
     8221 ttcgactttg ttattaccga gattggcggt acagtgggtg acatcgagtc tctgccctat
     8281 ctggaaagca tccgtcagct gaagtgggaa ctgggaaaag acgccttgtg cgtacacctt
     8341 acttatgtcc cctacctggc agctgccggt gagctgaaga ccaagcccac ccagcactcc
     8401 gtaaaggaac tgcaaagtgc cggtatccaa cccgatgtcc tcgtactgcg tacggagcac
     8461 gagttgagca ctaccctgcg caagaaggtg gctctgttct gcaatgtgga cgagaatgcc
     8521 gtggtgcaga gcatcgacgc gcctaccatc tacgaggtgc ccatcttgat gcagagccag
     8581 ggactggacg ttaccatttt gaagaaaatg ggacttcccg tcggtgatac tccgggactg
     8641 ggaccgtggc gtgctttcct cgaacgccgt cacaaagccg aagagactgc cccactgcac
     8701 atcgcattgg tgggcaaata tgacttgcag gatgcctaca agtccatccg cgaggccctt
     8761 tcacaagcag gaacctacaa tgaccgcaaa gtatcggtag acttcgtgaa cagtgaaaag
     8821 ctgactgacg agaatgtggc agaagccctg aaaggcatgg caggcgtact tatcggtcca
     8881 ggcttcggcg aacgcggcgt tgccggcaag ttcgtagcca tcaaatatgc gcgtacgcac
     8941 gacatcccca ccttcggtat ctgtctgggt atgcagtgta tcgccatcga atttgcccgt
     9001 aacgtactgg gttatgccga tgccaactca cgcgagatgg acgaaaagac accgcacaat
     9061 gtcatcgaca tcatggaaga gcagaagtcc atcaccaata tgggtggaac catgcgtctg
     9121 ggtgcctacg aatgtgttct gcagaaaggc agcaaggcat acgaggcata tggtaccgag
     9181 catatccagg aacgtcaccg tcaccgctac gagttcaaca acagcttcaa ggatgcctac
     9241 gaagcagcag gcatgaagtg tgtgggtata aaccccgaat cggacctggt ggaaattgtt
     9301 gagattcccg cattgaagtg gtttgtcggt acccagttcc atcccgaata cagcagtacg
     9361 gtattgcatc cgcacccact gttcgtagca ttcgtgaagg ccgccatcga aaatgaaaac
     9421 gaaaagaaat aatttgtaat aagtaatttg taatcaacaa agaatggata aaaataccat
     9481 cacaggtctt gttctgatag cgatattgtt agtaggtttc agctttctga gccgtcccag
     9541 ccaggagcag ttggaagcac agcaacgtta ctacgactcc atagcccagg tgcaacagcg
     9601 cgaagccgac ttgaaagcca aggcggaagc agccctggcc aacgaaagcg gagcggaagc
     9661 aagcgttgac tccactgccc tcttcttcga cgcccgtcaa ggaaccaact cgcaggtaac
     9721 catccagaac aacctggcag aaataaccgt agatacaaaa ggcgggcgca tagcttcggc
     9781 cacgctgaag gaatacatgg gacaagacaa gacgaccccc gtcacactgt tcagcggcaa
     9841 tgacgcctcc atgaatttcc tcttttacaa caagaaagag actatccaga cggaagacta
     9901 ttatttcacc gcagtaaacc gtacggacag taccgtcacc atgcgtttgt cggcagacag
     9961 caacagctat atcgacttta cctacagcat gcacaatgac acatacctga tagactttac
    10021 tatccaggca gtcaatatgg aaggcaagct ggcggctacc aacaattatg tggacatcga
    10081 gtggtctcag cgtgcccgtc agatagagaa gggttacacc tacgagaacc gtctggctga
    10141 actgacttac aaaatcaccg gagagggtac cgattatctg tccgccaaca agaacgacga
    10201 aaaggaagtt ccggaacgcc tggactggat tgctttcaag aaccagttct tctcttcagt
    10261 atttttggca gatgccgact ttgaaaagac caaactgagt tccaagatgg agactcaagg
    10321 cagcggctac atcaaggact attctgcgga gatgagcacg aagttcgacc ctgccggcaa
    10381 ggaacctacc cagctgttct tctacttcgg ccccaatcac tacaagactc tgaccgcact
    10441 cgacaaggga cgtgacgata agtgggagct gaaccgtctg gtctatctgg gctggccgct
    10501 catccgctgg ataaacaaat ggttcaccat caacatcttc gactggttgt ccagttgggg
    10561 tttgagcatg ggtatcgtac tgttgttcat gacgctgatt gtaaaggcag tggtattccc
    10621 ggctacgtgg aagacctaca tgtcttctgc caagatgcgc gtactgaaac cgaaaatcga
    10681 cgagataaac aagaagtacc ccaagcagga agatgccatg aagaagcagc aggaagtgat
    10741 gggcctctac agccagtacg gagtcagccc gatgggcgga tgtctgccga tgctgataca
    10801 gttccctatc ctgatggcct tgttcatgtt cgtgccgagt gccattgaac tccgccaaca
    10861 gagcttctta tgggcagacg acctttccac ttatgatgcg ttcatcaact tcccgttcca
    10921 tatcccgttc ctgggcagcc acctcagctt gttctgcctg ctgatgacgg ttaccaacat
    10981 attgaacacg aagtacatga tgcagcagca ggatacgggt gccaatccgc agatggctgc
    11041 catgaagtgg atgtcatacc tgatgcctgt catgttcctc ttcatattga acgactatcc
    11101 ttcgggattg aactattact acttcatctc tacgttagtc agtgtggtaa caacgctcat
    11161 catgcgcaag acaaccaatg aggaagccct tcttgctcag ttggaagcca acaagaaaga
    11221 cccgaagaag atgaagaaaa ccggtttcgc cgctcgtctg gaagccatgc agaaacagca
    11281 ggaacagatg atgaaagaaa aacagaacaa aaagtagtaa gactaccgtt caagatattc
    11341 ttttgcagaa agccggacaa tgacatttgc ccggctttct tatccttaca ccaacgaaaa
    11401 aattcacaga ctctaaatta tgcagactaa atacacttac aaacaaatct ggctcatagc
    11461 ctaccctatc ctaatcagcc tccttatgga gcagatgata ggtatgacgg acaccgcctt
    11521 cctcggacgt gtaggcgaag tcgagttggg agcatctgcc atcgccggtg tcttctatat
    11581 ggtcatcttc atggttgcct tcggtttcag catcggggca cagatactca ttgcccggcg
    11641 caacggcgaa cggcagtata aggaaatcgg tgacttgttc tatcagggca tctatttcca
    11701 agtcgggatg gcgacagtca tgttcctgct gtcctattgc ttctcgccga ttatcctgaa
    11761 acgcatcgta gcctcggaac atatctacga agcagccacc agctacctgc actggcgtgt
    11821 attcggtgcc ttcttctcgt tcagcgcagt catgttccgt gcctttttct tgggaaccac
    11881 ccagaccaag acactgacac tgaactctat cgtcatggtg ttgagcaatg ttgtattcaa
    11941 ctatatcctg attttcggta aattcggttt tcctgcactc ggcattgccg gagccgccat
    12001 cggctcctca ttggccgagc tggtttcgct gttattcttc atcctctata cccgtagccg
    12061 tatcgactgc tgcaagtacg ggctggaccg tattccgaag ttccggttgg acgtattgaa
    12121 acggatgctg aacgtctctt tctggaccat gatacagaat ttcttctccc tctccacctg
    12181 gttccttttc ttcctttatg tggagcatct gggagagcgc tcgctggcag tgaccaacat
    12241 tgtccgcaac gtgtccggca tactgttcat ggtactcatg gcgtttgcct ctacctgcgg
    12301 gtcactggtc agcaatctca tcggtgcagg ccactccgat tgcgtggcag gcaccatccg
    12361 gcagcacgta cgcatagcct acgtcttcgt acttccgctg gcattgcttt tcgcggtgtt
    12421 ccccaagctg attctgggaa tttataccga catacccgac ctgcaggacg ctgccgtaca
    12481 ttcgctctgg gtgatgtgct ccacctatct gttcctggtt cctgccaatg tctatttcca
    12541 ggcagtttcc ggaaccggca acacgcgtac ggcatggggg ttggagatgg ctacgctggt
    12601 catctacaca gcctatatca cctacattat tctgattctg caactcgacg tggccatctg
    12661 ctggacctcg gaaatggttt attccagctt tattctcatt ttctgctggc tatatatcaa
    12721 acgtgggaat tggcaaggaa ggaaaattta gtatctttgc attgaaataa ccgaaacaaa
    12781 aaacatatat gaaacaagta aatctactac ttatgtcagc agccatgaca ttggcctctt
    12841 gcggaggcac aaaagatgcc ggacagcagc aggacgcagc aacgctcatc cagcggtcgg
    12901 acatcaagat tgaaggaaag cgtatgacac ccgaggcact ctgggcgatg ggacgcatcg
    12961 gcagtgtggc cgtatccccc gacgaaaagc aaattgccta cacggtatcc tattacagcg
    13021 tgccccagaa caagagtaac agcgaagtct tcgtcatgaa tgccgacggt agtgacaata
    13081 cccagataac gcatgacgcc tggcaagaag gacagcccac atggttcaag gacggcaaga
    13141 agcttgcctt cctttgcaac gaaagcggca gcagccaggt atgggaaatg aatcccgacg
    13201 gcagcggacg caagcagctg acccaatacg agggagacat cgaagggttc tctttctcgc
    13261 ccgacggcaa gaaactcctt ttcattgccc aggtaaagac cgtgaagagt acggcagaca
    13321 aacatccgga ccttcctaaa gccaccggca tcatcgttac cgacctgatg tacaagcatt
    13381 gggacgaatg ggtgactact gctccccatc cattcgttgc cgatttcgac ggcaatgcca
    13441 tcagcaatgt cactgatatt cttgagggag agccatacga aagcccgatg aagccctggg
    13501 gcggtatcga gcagctggca tggagcccgt cttctgataa ggtggcctat acatgccgta
    13561 agaaaaccgg actggcgtat gccatttcca ccaactccga catttatatc tacgaccttg
    13621 cctccaagga aaccaaaaac atcacggaag aaaacaaggg atatgatacg aatccccaat
    13681 actctcccga cggcaaatac atcgcctggc agagcatgga gcgtgacggc tacgaagccg
    13741 acttgaaccg cttgtttatc atgaacctcg agaccggcga gaaacgtttt gtaagcaaag
    13801 ctttcgaatc gaacgtggac gccttcttgt ggaacaaaga ttcccagagc atctacttca
    13861 tcggtgtatg gcatggcgag acacagattt acaacatcga ccttgccgga aacgacaagc
    13921 ttacccggct caccgacggc atgtacgact atgcttcgct tgccctttgc ggagacaaga
    13981 ttatcgccaa acgccattcc atgagcatgg gcgacgaaat ctatgccgta aacagtgcac
    14041 gtaacggcga cgcttttgca gaagcagtgc aactgaccac agaaaacaag cagatttacg
    14101 accagctgga aatgggtaaa gtggaagccc gctggatgaa gaccaccgac ggcaagcaga
    14161 tgctgacctg ggtgatttat cctccgcagt tcgaccctaa caagaagtac cccaccctcc
    14221 tcttctgtga aggcggtcct cagagtcccg tcagccagtt ctggagctac cgttggaatt
    14281 tccagattat ggcggcaaac gactatatca tcgtagctcc caaccgtcgt ggtcttccgg
    14341 gcttcggtgt agagtggaac gaagccatca gcggtgatta tggcggccag tgcatgaagg
    14401 actacttcac tgccattgac gaaatggcca aggaaccttt cgtcgacaaa gaccgcctgg
    14461 gttgcgtagg cgccagcttc ggaggcttct ccgtatattg gcttgccgga caccatgaca
    14521 aacgcttcaa ggcattcatc gcacacgacg gtatcttcaa catggaaatg caatatctgg
    14581 aaacggaaga gaaatggttt gccaactggg atatgggcgg tgcttattgg gaaaagaaca
    14641 acgctacggc acaacgcact tttgccaact ccccgcatct cttcgtcgac aaatgggaca
    14701 cccctatcct ctgcatccac ggagagaagg acttccgca
//
