LOCUS       c00067_gnlPro..        17641 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CJFJKPBL_67.
ACCESSION   c00067_gnlPro..
VERSION     c00067_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 08:49:29
            Original ID  :: gnl|Prokka|CJFJKPBL_67
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 7647
            Orig. end    :: 25288
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17641
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[17647:20618]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12971
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..17641
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17641
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             460..768
                     /locus_tag="ctg67_9"
                     /transl_table=11
                     /translation="MEIRELLSKPVWQMTGEEFILLNRHALQEREARAAQPAADTEKKY
                     VYGIGGIARLFGCSMPTANRIKKSGKIDRAITQIGRKIIVDADMALELAGHKSGGRR"
     CDS             781..1806
                     /locus_tag="ctg67_10"
                     /transl_table=11
                     /translation="MEYRERKEVTPEAAVILWQASRLDLSEDYERAPEILKVHGSVIGT
                     LGNFSASIGKAKSKKTFNVSAIVAAALKNGTVLSYTAELPENRRKILYVDTEQSSYHCA
                     KVAKRILRMAGLPTGRNHKDLEFLVLRKYTPEERIAIVREAIYRTENVGLVVIDGIRDM
                     VYDINSPSESTKVISLLMTWTGERHIHIHTILHQNKGDENARGHIGTELSNKAETVLQV
                     EKDEKDPDISTVKAAHIRAMNFEPFAFRINEEALPELQDEYLFKHKDPGKGKREKFDPY
                     KDRSEEHTSELQSXXXXSLHDALPICSTPTRTSQRSSTASHWKRHSHSKMNTATRSLRK
                     N"
     CDS             complement(1921..2217)
                     /locus_tag="ctg67_11"
                     /transl_table=11
                     /translation="MCNGLHPLYFTLLYICPQTKVKRFPVCAVMVEAGYETIPFFRTVI
                     PLFLSSVNIIFSFRPYLFVYYGLYPLYFTSVYIWYGTKVKWFPYNTANSENRF"
     CDS             2272..3240
                     /locus_tag="ctg67_12"
                     /transl_table=11
                     /translation="MNMNEAKQICIEEYLHSLGYSPVRQQGGSLWYNSPFRDEQEPSFK
                     VNTERNLWYDFGAGKGGNIIALAQELYASDSLPYLLERIKEQAQNVRPASFSFGKQPLS
                     KPSFRQLEVVPLSSPALYAYLRQRGINTELAKRECREVRYLTGETPYYAIGFPNRSGGY
                     EIRNKHFKGCIAPKDITHIRQSEPKEACYIFEGFMDYLSFLTLRLERCPDRPELDGQDY
                     IVLNSTSNLSKAIRPLGGYGCIHCFLDNDKAGMEAVQELREEYGLRVRDASHIYGGYND
                     LNDCLRSKQNGQAEHQQQRPEPEKGQRQAEQLKKKNKGIRM"
     CDS             3628..4764
                     /locus_tag="ctg67_13"
                     /transl_table=11
                     /translation="VSANQVKAIRILLTGSNKDMKQMEAEGRIEDWCNDSLKWIRETYG
                     EQNLVSAVLHMDEKTPHIHATVIPIVTGERRKAGQEEQNGKKKYRKKNPQDVRLCADDV
                     MARHRLKHYQDTYAQAMNKYGLQRGVDGSLAKHISTMQYYKQLVEQQDSLQENIENLLG
                     LEEEAMKKLKQVKGEINVQKMKGAAVNATTAIADGVSSLFGGSKVKRLEEENENLKRNI
                     VNLQKQVQAEQREQTKMENRHSSEINRVDWSYRQKIAEYDNRLELIDTYFPIVKELMPI
                     AEQCREVGFTEELTRRIVSLQPVEFKGRLYSKEYKEKFRTEHSTATVERNPQEKGKFRL
                     CIDGIPILDWFRKKFQEIKEKLRLNTPVENKQRKGLKI"
     CDS             complement(4897..5406)
                     /locus_tag="ctg67_14"
                     /transl_table=11
                     /translation="MKKVCMLLLWLFICNIGLVLAQGRRFEFELGANYPIGLQKNGYKE
                     NHVGFYLNGIYRFSTNPLSVNLKLGYESYTIVLNNTFNGRSLSLMPAANYHFLRNESVD
                     SYVGLGTGVSIDNIDVGVFNEGYKLHFAVAPQVGIRFINHINVYLQYYVTHKDFSRLVL
                     GVGYVF"
     CDS             complement(5472..7019)
                     /locus_tag="ctg67_15"
                     /transl_table=11
                     /translation="MRILRYTLFLFAIGLISCEQEFDKKEQQSDCCSFQNLPKYPEQVV
                     NINVHNYIPDMGDKVLSSPSHIHTRASEIISETLWDNGFGKTIHAQADESIVLDNLNRY
                     IYPGSILDGASVANQDYKTISVHYKPINVSVSFPAQKVTGVLEKPSLSSCRQLVMDLMH
                     QKGIGQQSASVHFDIHRFTSYDELKMTFGSNANTSFLFWGSSSSQQEHKERISKSSGLY
                     IRFIQKYFTIDMDIPEKSFIEGSINAQYSPVYVSSIAYGRVGILTLETDEIYENAESIV
                     KKAVNGFLYNKKEFLTVEEKGFFDEARMKVYVGGGNGDSGVKTLTGFDDFIKFISEGGH
                     FSAETPGKPIFCSFAYLSDHSPYKVKFKIDIDSDPVYARIEYRNLKNDSYVGRSLQREK
                     IIGDVHLAFYADRTAKIPTVAPRYISFNIVEHSRHYLKARIPRTEKDDTTVEEFVKSNN
                     SRGTELQLKHDLLLTEFVWTHNNPRRTRYEQNTFRYSLSEGGFYKILPAINEPKKWR"
     CDS             complement(7035..8141)
                     /locus_tag="ctg67_16"
                     /transl_table=11
                     /translation="MKQYVYLLILPIMFLISCSDDTVEEMGGSNHVLLERYPQEVINIS
                     MDNPESFASFNKTSVTRSSELLKDSVWSSGNGHTLIYETNEHIPTQGLMRYIYLGSILQ
                     GGSIEKQRFVPIVKPMDPITISYSFPARWVTDIIAKPSLSAQRQSLQNIMNKEGMTGKQ
                     LGSFTYNMRQFSYFEELKLAFGANVNIGGLLNIDVSLDKGKIRKKTGLFAKIVQRNYTV
                     DMDLPADGNILLNHDDMGSVGKYDPIYISSITYGRMALISIESSESYDKVRIALQAALQ
                     AKVVNGKLSFNLEQEKILKEAEVNVMVYNGEGEGTVKTAKGWNEFQDFIIQGGRFSKDL
                     PGDAIFYTASYLSDNSPFYSKFKIHLEN"
     CDS             complement(8174..9013)
                     /locus_tag="ctg67_17"
                     /transl_table=11
                     /translation="MKKIFILLFVSLALFSCEKEENNKIFKYQLLPSENVSKPFSCLGE
                     KRTITFTIIQKTLIDDILDSEVPIIPKDVSIEFDKTLFSDIETKIKGDQVVLNITSNIN
                     KEDKILNVDLQISYSTINGIKVEKIPLIIDKGKLTFVYKIHSEQNPFVLPAEGGKFELP
                     FICKKQTYLNDQFIEETYSSLNGLRFKTISTGNVWFLTVRKDGEKIGFYKFTFVGEGPY
                     NQKTDPECYFNIYTHDANLITDNPTEIFRQDFIQPQTPGEDYYKPSRSSYKHGTFDF"
     CDS             9033..9251
                     /locus_tag="ctg67_18"
                     /transl_table=11
                     /translation="LQIKGFFLYNKIPINWYFITNNHSISLLCPKHENKSITYKSCKQI
                     HDQHNKINRLCIFAICIYAKSYKFLYQ"
     CDS             complement(9848..9997)
                     /locus_tag="ctg67_19"
                     /transl_table=11
                     /translation="MIKLEVVVILFFRAHKVTIIFHIISINMLYFMLFNIKYLLIAILR
                     KRLD"
     CDS             10001..12229
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg67_20"
                     /sec_met_domain="Gly_radical (E-value: 1.7e-46, bitscore:
                     148.1, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1173.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSSEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERENNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     KFEEVMDNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIEGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATDEDRIENLVTMMDGYFTKGAHHLNVNVLN
                     RDMLYDAMEHPENYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             12243..12971
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.5;
                     E-value: 1.4e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg67_21"
                     /sec_met_domain="Radical_SAM (E-value: 5e-29, bitscore:
                     92.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGITFSGGEPTFQAKALVPLVRELKEKGIHVCLDSN
                     GGLWNEDVEELFRLTDLVLLDIKEFNPNRHQTLTGRSNEQTIRTAAWLEEQEKPFWLRY
                     VLVPGYSDFEEDIRALGEALGKYKMIQRVEILPYHTLGVHKYEAMGQEYKMKGVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(12964..13413)
                     /locus_tag="ctg67_22"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRVDCDFTAKDVDTAHRYRGFSCWGYHYYIRK
                     SGEIEPMRDKDTVGAHARGYNAISLGVCYEGGLDENGKAADTRTPRQKEALHRLVHELL
                     QRYPEAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVIGEFSIN"
     CDS             complement(13400..13567)
                     /locus_tag="ctg67_23"
                     /transl_table=11
                     /translation="MKEIVSRILDVIMYLIPFFGKRKRDRVVREVRYHTTCKEVCKVKT
                     TEREKEHEKD"
     CDS             complement(13627..14130)
                     /locus_tag="ctg67_24"
                     /transl_table=11
                     /translation="MAMTVSYSVVPRKNPAKKSEPAKYYAQAQASGELDFEELCEAITS
                     RSTCTETDVRAAISGILYEVKRALKAGRIARLGDLGSLQIGLNSEGAASVKEFSGSMIK
                     GAHLIFRPGKTLAELMKILSYQQVQTRAVAQAGAGDGGGEDPDKNPDSGGDGSGDEEAP
                     DPTV"
     CDS             14641..16755
                     /locus_tag="ctg67_25"
                     /transl_table=11
                     /translation="MKHFTIFQGFYYAIAEMTEEEIVSTIGSFTYREKVEEIRRIFAEQ
                     GEKAANEKKKELPAIAFSASYRGRRTKVNLVKYLGHIVIDIDHLSKEELARILPIIKRC
                     DYTRIAFISPKGMGVKIIVRACHPDETLPETLQEIEDFHHAAYTRLVSFYTELCQIEID
                     TSGQDVARTCLFSYDPEIYFNPNADAFLVDQPQASYKVSNRKNLSGSKQQTPPDGPPTN
                     EDTALNAHSANASLVLTLTYYHNKSEKYIVGNRNNYLHHLSCTFNRYGIPQEEASAFIK
                     SQFTDFPADETASLINSAYAHTDEFNTCKLNGTQKRILRIEQYISEHYETRYNEVLHIM
                     EYRRRHPDTEKPEPFRILDEMMENSIWIEINELGYACTVKTIENLIYSDFSQSYHPIRE
                     YFELLPEWDGTDYIRILADSVQTSHQEFWAECLERYLVAMCAAATQENIVNHTVLLLCS
                     EIQNIGKTTFINNLLPPELRAYLSTGLINSNNKDDLAKITQAMLINLDEFEGMSGRELN
                     AFKDLVTRKVISFRLPYARRSQNFPHTASFAGTCNYQEVLHDTTGNRRFLCFHPYSIQF
                     ITINYAQLYAQIKYLLNKPGYQYWFTQADNERLEENNEAFIFHSPEEEMVLTHIRKPER
                     FEKVYYLTVSEIAELIRERTGYQYSIGSKIQLGKVMTKHHFESKKGNNGRRYAVFIIDI
                     EQVKSNRLYE"
     CDS             complement(16956..17156)
                     /locus_tag="ctg67_26"
                     /transl_table=11
                     /translation="MEAKTNEEFFNVSALIDERFGKEGTASRAEAEEKAYAFYTGQIIE
                     XXXXPYTTLFRSKRLKSLRLN"
     CDS             complement(17137..17469)
                     /locus_tag="ctg67_27"
                     /transl_table=11
                     /translation="MKREIIAYKGYFKEFFENLDAGTQDKILYVLMLLQTQDRIPLKFM
                     RLIEEGLYELRIEYQSNIYRIFFCFDEGRIVILFNGFQKKTEKTPKKEIDKAKILRKEY
                     YGSKNK"
ORIGIN
        1 cgagcagatt aaaggtgaga aaggatgaaa aggcacgtgt atgctacctg atatttctca
       61 tgggagaaac actttccaaa cccgacagag aaaaatggaa ggaggaaatc atgaaactgc
      121 tggagataga tataaaatat tacaagtcca aatacaaggc acccgtaccc cggaccgatt
      181 tacccagtga cagcaatcag atatttgcga aggaaatgca gtcaatattc cgatagtcag
      241 cgatacgcca cgacattcca cgaaacaacc acttttacca cccgaaatat ttttcaccac
      301 tctttattat cttctgatat ttagtgagat agcgtgatac tccattcacg ctatccacat
      361 ccttaccacc cgtatccggg attaactttg cactgttcga acgaaacaaa aaaagcccgt
      421 gcgcagggct tacagtacaa acgttaaatt cattccaaca tggaaatcag agaactttta
      481 tcaaagcccg tatggcagat gacgggagaa gaattcatat tactgaaccg acacgcctta
      541 caggaaaggg aagcgagagc agcacagccc gcagccgata cggaaaagaa atacgtgtac
      601 gggataggcg gcatagcacg cctgttcggg tgcagtatgc ccacagcaaa ccgcatcaaa
      661 aaaagcggga agatagacag agccattacg cagataggac gcaaaatcat cgtagatgcg
      721 gacatggcac tcgaactggc aggacacaaa agcgggggac gcagataagg aggtacggac
      781 atggagtaca gagaaagaaa agaagtcacg cccgaagcgg cggtgatact gtggcaagcc
      841 tcacggctcg acctttcgga agactacgag agggcacccg aaatactgaa agtacacggt
      901 tccgtcatag gcacgctggg gaacttcagc gcatcaatcg gaaaagcaaa gagcaagaaa
      961 accttcaatg tttccgcaat cgtggcggct gcactgaaaa acgggacagt gctaagctac
     1021 acggcggaac tgcccgaaaa caggaggaaa atactctatg tggataccga acaaagttcc
     1081 taccactgtg cgaaagtggc aaaaagaata ttgcgcatgg cgggactgcc gacaggcagg
     1141 aaccataaag accttgaatt ccttgtccta aggaagtaca cgcccgagga acgaatagca
     1201 atcgtgaggg aggctattta ccgcaccgaa aatgtagggc tggtagtcat tgacggaata
     1261 cgggatatgg tgtacgacat caacagtcct agcgagtcca cgaaggtaat ctccctgctg
     1321 atgacatgga cgggggaaag acacatacac atacacacca tactgcatca gaacaagggg
     1381 gacgagaacg caaggggaca catcggaacg gagcttagca acaaggccga aacagtgctg
     1441 caagtggaga aggacgaaaa ggaccccgac atcagtacgg tcaaggcagc acatatcagg
     1501 gcgatgaact tcgaaccgtt cgcattccgc atcaacgagg aggcattgcc cgaactgcag
     1561 gacgaatacc tgttcaaaca caaggatccg ggaaaaggga aaagggagaa gttcgacccc
     1621 tacaaggaca gatcggaaga gcacacgtct gaactccagt cacnnnnnnn nnnttcccta
     1681 cacgacgctc ttccgatctg ttcgacccct acaaggacat cacagagaag cagcaccgca
     1741 tcgcactgga agcggcattc acactcaaag atgaatacgg ctacaaggag cttgcggaag
     1801 aattgaggaa aacctacgcc tctgtcggtg tcatgcttgg gggaaacagg ctgacagacc
     1861 tcattacagt actgaaaaac aaacggatga tagtacagga gaacggcagg aaatacacct
     1921 tcaaaaccga ttttcactat tagcggtatt gtatgggaac cactttactt tagtcccgta
     1981 ccatatatat acggaagtaa agtaaagtgg atatagcccg taatatacaa aaagatacgg
     2041 gcgaaaagaa aaaataatat tcacacttga caagaacaac ggtatgacag tacgaaaaaa
     2101 gggtatggtc tcatacccgg cctccaccat gacggcacag accggaaacc gctttacttt
     2161 agtctggggg catatatata gcaaagtaaa gtaaagcgga tgcagcccgt tacacatgaa
     2221 agggtacggg cgaaaacccc aaaaacaata tctacttaaa acagaaatat gatgaacatg
     2281 aatgaagcga agcagatatg catagaggaa tatctgcaca gtcttggata cagtccggta
     2341 aggcaacagg gtggtagtct atggtacaac tcaccgttca gggacgaaca ggaaccctcc
     2401 ttcaaggtga acaccgaacg caacctatgg tatgattttg gcgcaggcaa aggtggtaat
     2461 atcatcgcac tggcacagga gctatacgca tccgacagtc tgccctacct cttggaaagg
     2521 ataaaggagc aggcacaaaa cgtgcgcccg gcctctttct cttttggcaa gcaacccttg
     2581 tcaaagccga gtttccggca gttggaggta gtaccgctct cctctcccgc cctgtatgcc
     2641 tacctgcggc aaaggggaat aaatacggaa ttggcaaaaa gagaatgcag ggaggtccgc
     2701 tatctgaccg gggaaacccc atactatgct ataggcttcc ccaaccgttc gggaggatac
     2761 gagatacgca acaagcattt caagggatgc atagcaccga aggacatcac ccatatacgg
     2821 caatcggagc cgaaggaggc atgctacatc ttcgagggat tcatggacta cctctctttc
     2881 ctcaccctgc ggctggaaag gtgtcccgac cgtcccgaac ttgacgggca ggactacatc
     2941 gtactgaact cgacttccaa cctctccaag gcaatccgac cattgggcgg ttacgggtgc
     3001 atccactgtt tcctcgacaa cgacaaagcg ggaatggaag ctgttcagga actgcgggag
     3061 gaatacgggc tgcgcgtccg ggacgcgtcg cacatatacg gaggctacaa cgacctgaac
     3121 gactgcctgc ggagtaagca aaacggacaa gccgaacatc agcagcagag accggagccg
     3181 gagaaaggac aacggcaggc agagcaactg aaaaagaaaa acaaaggtat caggatgtaa
     3241 ccgtagagcc accggaaggc tttgaaaaaa gccatagctc attagggctt tttcttaacg
     3301 caatgcacac attgctaaaa aagccccaac gagccatagg ggcgccgccc ctttggaaac
     3361 cccgtctgcc atgcggcata aaagcaaggc aggggaagta ttaacctgaa attattgaca
     3421 gttatgggat atgcagtttt gcatctggaa aaggcaaaag ggacggacag caggatgtcc
     3481 gcacacatag agcgcaccgt tcacccgaag aatgcggaca gaacgcgcac acacctgaac
     3541 cgggagctcg tacagtttcc cgaaggggtg aggaaccgca cgcaggcgat agcccaccgg
     3601 atagaaacgg caggcatcag acgcaaggtg agcgccaatc aggtgaaggc aatccggata
     3661 ctccttaccg gaagtaacaa ggacatgaag caaatggaag cggaaggacg gattgaagac
     3721 tggtgtaacg acagtctgaa atggatccgg gaaacatacg gggagcagaa cctcgtatcg
     3781 gcagtactgc acatggacga gaagacacca cacatacacg ccacagtcat accgatagtg
     3841 accggagagc gaaggaaagc cggacaggaa gaacagaacg ggaaaaaaaa gtacagaaag
     3901 aagaacccgc aggacgtgag actctgcgca gatgatgtaa tggcaaggca caggctaaaa
     3961 cactatcagg acacttatgc ccaagccatg aacaagtacg gcttgcagag aggcgtggac
     4021 ggctcattgg caaagcatat ttccaccatg caatactaca agcagctggt ggagcagcag
     4081 gacagcctgc aagagaacat agaaaacctg ctggggctgg aagaggaagc aatgaaaaaa
     4141 ctgaagcagg taaaggggga aatcaacgtg cagaaaatga agggggcggc ggtgaacgcc
     4201 accacagcca tagcggacgg ggtgagctca cttttcggag gcagcaaggt taagaggctg
     4261 gaagaggaga atgaaaattt gaaacggaac attgtgaatc tgcaaaagca ggtgcaagcc
     4321 gaacagaggg agcagacaaa aatggaaaac cgtcacagca gcgagataaa cagagttgac
     4381 tggagctacc ggcagaaaat cgcagaatac gacaatcggc tggaactgat agacacctac
     4441 tttcctattg taaaggaact gatgcccata gcagaacaat gccgggaagt gggcttcacc
     4501 gaagaactga caagacgaat tgtcagcctg caacccgtgg agttcaaggg aaggctctat
     4561 tcaaaggagt acaaggagaa gttcaggacg gagcactcaa cggcaacagt ggagaggaac
     4621 ccgcaggaga aaggaaaatt caggctgtgc attgacggaa tacccatact cgattggttc
     4681 aggaagaaat ttcaggaaat taaagaaaag ttaaggctaa acacacctgt tgaaaacaag
     4741 caacgaaaag gattgaaaat ataatcactt aataacgaga ggctataaat tattagtgcc
     4801 agtaaaagaa tatactcttt actggcacct gttaaacgca aattgacacc ctaaatctaa
     4861 caaatataaa aaaatctatt cttcacttgg acaatatcag aaaacataac caactcccaa
     4921 taccaacctg gaaaaatctt tatgtgtcac ataatactgt aaatatacat ttatatggtt
     4981 tataaatcta ataccaactt gtggagccac cgcaaagtgc aacttataac cttcattgaa
     5041 aactcccaca tctatattat caattgaaac accagttccc aaaccaacat aggaatcaac
     5101 agattcattc cgtaagaaat gataattagc tgccggcata agagataaag atcttccatt
     5161 aaaagtatta ttcagtacaa ttgtgtaact ttcataacct aattttagat ttacacttaa
     5221 cggattggtg gaaaacctat atattccatt taaataaaac ccaacatgat tttctttata
     5281 tccattcttt tgtagcccaa ttggataatt ggctcctaat tcaaattcga atctccttcc
     5341 ttgtgctaat accagcccaa tattgcatat aaataaccaa agaagtaaca tacatacttt
     5401 tttcataacc aatttatctt ttaataccat atctcttatt tatttgttcg acaaggagtg
     5461 ctaacttcaa attatcgcca cttctttggc tcatttatag cagggagaat tttgtaaaaa
     5521 ccaccttcac taagactata tctgaaagtg ttttgttcat atcgagttct tcttgggtta
     5581 ttatgcgtcc aaacaaattc tgtgagcaac aaatcatgtt ttaattgtaa ttcagtccca
     5641 cggctattat tactcttaac aaattcttct actgttgtat catccttttc tgttcttggt
     5701 attcgagcct tcaaataatg tctgctatgt tctacaatat taaaagaaat gtatcttgga
     5761 gcaactgtcg gaatcttagc cgttctatca gcataaaagg caagatgtac atcgccaatt
     5821 atcttttctc tttgtaaaga tctacccaca taggagtcat tttttagatt ccgatattca
     5881 attcttgcat atacaggatc gctatcaata tcaattttaa atttaacttt ataaggtgaa
     5941 tgatccgaca aatacgcaaa gctgcaaaat ataggtttac caggtgtctc tgcagaaaaa
     6001 tgccctcctt cacttataaa tttgataaaa tcgtcaaatc cggtaagggt ctttacacca
     6061 ctgtcaccat ttcctccccc tacatatact ttcattctgg cctcatcaaa aaagcccttt
     6121 tcttcaactg tcagaaattc ttttttgtta tataaaaagc cattaacggc cttctttaca
     6181 atggactccg cattctcgta tatttcatcg gtttcaagag ttaatatgcc gacccttcca
     6241 taagctatgg agctcacata gacaggagag tattgggcat tgatactacc ttcaataaaa
     6301 ctcttctcag gaatatccat atcaatcgta aaatatttct gaataaacct tatatataag
     6361 ccactacttt tactaattcg ttccttatgt tcttgttggg aagatgacga cccccaaaat
     6421 aaaaagctcg tattggcatt tgatccaaaa gtcattttca gctcatcata agatgtaaaa
     6481 cggtgtatat caaagtgtac ggaagctgat tgttgcccta tacctttctg atgcatcaaa
     6541 tccattacca actgcctaca tgaagacaaa gatggctttt caagtacacc tgtaactttt
     6601 tgggcaggaa aggacacaga gacatttata ggcttatagt ggacactgat tgttttataa
     6661 tcctgattgg caacgcttgc cccatccaag atagagccag gataaatata tcgattcaga
     6721 ttatccaaaa ctatcgactc atctgcctgt gcatgaattg ttttaccaaa cccattatcc
     6781 cataatgtct cagaaatgat ttctgaagct cttgtatgga tatgtgaagg agaagataaa
     6841 accttatctc ccatatcagg aatatagtta tgcacattta tattcaccac ttgttcggga
     6901 tacttaggta gattttgaaa agaacagcaa tcagattgct gttctttttt gtcaaattct
     6961 tgttcacatg aaattaatcc tatagcaaat aaaaacagag tatatcttaa gattctcatg
     7021 gttctaagtt attgtcaatt ttctaaatgg attttaaatt tggagtagaa gggagagtta
     7081 tcagataaat aactcgcagt ataaaaaatt gcatctcccg gcaggtcttt agaaaatcga
     7141 cctccttgaa ttataaaatc ttgaaactca ttccacccct tcgcagtttt aacagtgcct
     7201 tctccttctc cattatacac catgacgttc acctctgctt ctttaagaat cttttcttgt
     7261 tcaagattaa aagataattt cccatttaca actttagctt gtaaggcagc ttgtaaggca
     7321 attcttactt tatcataact ttcagaagat tctatcgaaa ttaaggccat tcttccataa
     7381 gtaatggaac tgatataaat aggatcatac ttaccgacag atcccatatc atcatgattt
     7441 aaaagaatat ttccatcagc aggaaggtcc atgtcaacag tgtaattacg ttgtactatt
     7501 ttcgcaaaca atccggtttt ctttcttatt tttcccttat caagactgac atcaatatta
     7561 aggagcccgc ctatgttgac atttgctcca aaagcaagtt ttaactcttc aaaataggaa
     7621 aattgcctca tattataagt aaaagacccc aactgtttac ctgtcatgcc ttctttattc
     7681 attatattct gcaaagattg cctttgtgct gaaaggctcg gttttgcgat aatatcagta
     7741 acccaacgag ctggaaaaga atatgatatt gtaattggat ccataggttt tacaatagga
     7801 acaaagcgct gcttttcaat agatccacct tgaagaattg aacctaaata aatatacctc
     7861 attaaccctt gagttggtat atgttcattt gtttcataaa ttaatgtatg tccatttcca
     7921 ctactccata cactatcttt caataattca gaagaacgag taacggaggt tttattaaat
     7981 gaagcaaagc tttctggatt atccattgaa atatttatca cttcttgagg gtatctctca
     8041 agaagaacat gattagagcc acccatttct tcaactgtat catcggaaca tgaaattaaa
     8101 aacataattg gcaaaatcaa caaatataca tactgtttca taattaatat aattaaggtt
     8161 aatactgaat atgttaaaaa tcaaaagtac catgtttata agaggatcga gaaggtttat
     8221 aataatcctc acccggggtc tggggttgta tgaaatcctg tctgaatatt tccgtaggat
     8281 tatctgtaat caaatttgca tcatgggtat atatgttaaa ataacactct ggatctgttt
     8341 tttggttata tggtccttct cccacaaaag tgaatttgta aaaacctatt ttttctccgt
     8401 cttttctgac cgtaagaaac cagacattac cagtacttat cgttttaaat ctcaatccat
     8461 ttaatgatga ataagtttcc tctataaact gatcattcaa atatgtttgt tttttacaaa
     8521 taaagggcaa ttcaaatttc ccaccttcag ctggtagaac aaaaggattc tgttccgaat
     8581 ggattttata cacaaatgtc aacttccctt tatctataat taggggaatt ttttctactt
     8641 ttataccatt aatagtagag taagaaatct gtagatcaac attcaaaatt ttatcttcct
     8701 tattaatatt tgaggttata tttaatacaa cttgatcacc ctttattttt gtctctatat
     8761 cagaaaaaag agttttatca aattctatcg aaacatcctt gggaataatc ggaacctctg
     8821 aatctaaaat atcatctatc aatgtttttt gaataattgt aaaagtaata gtacgtttct
     8881 cccccaaaca actaaatggt ttagatacgt tctcacttgg cagcaactga tatttaaaaa
     8941 ttttattatt ttcttctttt tcacaggaaa ataatgctaa ggaaacgaac agaagaatga
     9001 atattttttt catattaata caatttagtt ttttgcaaat taaaggattt ttcctgtaca
     9061 ataaaatacc aattaattgg tattttatta caaataacca ttcaatttca ttattatgcc
     9121 caaagcatga aaataaaagt ataacataca agagctgtaa acaaatccac gatcaacaca
     9181 ataaaataaa tcgtttatgc atctttgcga tatgcattta tgcaaaatca tacaaatttc
     9241 tttatcagta attcattgac aaaatgaaat gtactttaaa agcccaaagt tatattcaat
     9301 tcataaccta aatgcctatc caatataaaa ataatgcgtt tagcaccaag atacaaacag
     9361 aacaacacaa aatcaagctc taaaggaatg tattactatt ataaaagaca gaattattcg
     9421 ggagattccc tactctaaaa aagttaaaga aagaaaatga ttcaaataaa tattagtata
     9481 acaatatcac caacaacaca atatcccctt ttcaaattat acaataaata atagttaaag
     9541 caactaaaga cagtgcaaag ccaaataagt aataaaagag caaagtatta aataaagcaa
     9601 aaacacccaa ttttactttt tagggtgtaa aattgggtgc cattcttgta aatcactgat
     9661 tatcagcatt tattgcggag agacagggat tcgaaccccg ggtacctcgc ggtacaacgg
     9721 ttttcaagac cgccgcaatc gaccactctg ccacctctcc aaaacttcct tatcagaagt
     9781 gcttttcgtt aaaagcggtg caaaggtacg aagatatttt aaacttgcaa gagttttcac
     9841 taaaaattta atctaatctt ttcctaagga tagcaattaa taggtatttt atgttgaaaa
     9901 gcataaaata gagcatattt atgctgatta tatgaaaaat gattgtaact ttgtgcgctc
     9961 taaagaatag gataactaca acctctaatt ttatcatttt atggaattaa acaagatctt
    10021 taaagacggt ctttggagca gcgaaatcaa cgtcagagat ttcgtaagtc ataacatcac
    10081 tccgtattac ggagatgctt cattcctcga aggacctaca gaacgtacca aagccgtatg
    10141 gaaccgctgc ctcgaagcac tggcagaaga aagagaaaac aacggtgtcc gctcattaga
    10201 taatgttacc gtatcaacca tcacttccca caaggccgga tatatcgaca aggaaaacga
    10261 actgatcgtc ggcctgcaga cagacgaact tctgaaacgt gccatcaagc ctttcggagg
    10321 tatcaacgta gtcagcaaag cctgtcacga aaacggcgtg gaagtggacg accgcgtaaa
    10381 agatattttc actcactacc gcaagacgca caacgacgga gtattcgacg tatatacgga
    10441 agaaatccgt tccttccgtt cgctgggatt ccttaccgga cttcccgaca attatgcacg
    10501 cggacgcatc atcggtgact accgccgtat ggcactttac ggcatcgacc gtctgatcga
    10561 agcaaagaag gaagatttgc acaacctcac cggtccgatg acagaggccc gcatccgcct
    10621 gcgcgaagaa gtggcagaac agatcaaggc actgaaagac atgaaagtga tgggcgaata
    10681 ctacggtctc gacctgagcc gtcccgctta cacggcacaa gaagccgtac agtgggtata
    10741 tatggcttac cttgccgccg tcaaagaaca agacggtgcc gccatgtcac tgggtaacgt
    10801 ttcttctttc ctcgatatct atctggaata tgaactgagc aaaggaacca tcaccgaatc
    10861 attcgcgcaa gagctgatcg accagtttgt catcaaactg cgtatggtcc gccacctgcg
    10921 tatgcaatca tacaacgaca tctttgcagg cgacccgacc tgggtaaccg aatctctggg
    10981 cggacgtctc aacgacggac gtaccaaagt gacaaagacc tccttccgtt tcctgcagac
    11041 attgtacaac ctcggccctt caccggaacc gaacctgacc gtactctgga gcccggaact
    11101 tccggaagga ttcaaagaat tctgtgcaaa ggtttctatc gacacttctt ctatccagta
    11161 cgaaaatgac gacctgatgc gcgaagtacg tcagtccgac gactacggaa tcgcctgctg
    11221 cgtatcatac caggaaatag gtaagcagat tcagttcttc ggtgcccgtt gcaacctggc
    11281 caaagccctg ttgcttgcca tcaacggcgg acgttgcgag aataccggta cagtcatggt
    11341 gaagaacatc cccgtactga ccagtgacac gctgaagttc gaagaagtaa tggacaacta
    11401 caaaaaagtg ctgaccgaaa tcgcccgcgt atataacgaa gcgatgaaca tcatccacta
    11461 tatgcacgac aagtattact acgagaaggc ccaaatggct cttgtagata cgaacccgcg
    11521 catcaaccta gcttacggtg tagccggact ttccatcgcc ctcgattcac tgtctgccat
    11581 caaatatgcg aaagtaactg cccgccgcaa tgatatcggt ctgacagaag gcttcgacat
    11641 cgaaggagaa ttcccttgct tcggtaacga caacgacaag gtagaccacc ttggcgtaga
    11701 cctggtatac ttcttcagcg aagaattgaa gaaattgcct gtttacaaga atgcccgtcc
    11761 taccctctcc ttgctgacta tcacttccaa tgtgatgtac ggcaaaaaga ccggtgctac
    11821 tcccgacgga cgtgccaaag gtgttgcctt cgctccgggt gccaacccga tgcacggacg
    11881 cgacaagaat ggtgcgatcg cttctctgag ttctgtagcg aaacttcgtt accgtgactc
    11941 acaggacggt atcagcaaca ccttctctat cgttccgaaa tcactgggtg ctacggacga
    12001 agaccgtatc gagaacctcg taacgatgat ggacggttac ttcaccaaag gtgcccacca
    12061 cctgaacgta aacgtactga accgtgatat gctgtacgat gccatggagc atccggaaaa
    12121 ctatccgcag ctgactatcc gcgtttccgg ctatgccgta aacttcgtga agctgagccg
    12181 cgaacaccaa ctggaagtta tcagccgtag cttccacgaa cgtatgtaat ctattactct
    12241 atatgatgat aaacgtacat tcatacgaaa gtatgggaac attcgacggg ccgggcttac
    12301 ggctcgtcgt ttttcttcaa ggatgcaact tccgttgtct ctattgcgcc aatccggata
    12361 cgatagcagg aaagggaggc acgcctaccc caccggaaga aatcgtccgc atggcaatga
    12421 gccagcgccc cttcttcggg aaacgaggag gaatcacttt ctccggaggc gaaccgacgt
    12481 ttcaggcgaa agcactcgtc ccgctggtcc gcgaactgaa agaaaaaggc atccatgtct
    12541 gtctggacag caacggagga ctttggaacg aagacgtaga agaattattc agactgaccg
    12601 atcttgtgtt attggatata aaggaattca accctaaccg ccatcaaacg ctcaccggaa
    12661 gaagcaacga gcaaaccatc cgcacggccg cctggctgga agaacaggag aaacctttct
    12721 ggctacgcta cgtgctagtg cccggataca gcgattttga agaagacata cgcgcactgg
    12781 gagaagcact cggaaaatac aagatgatcc aacgggtgga aatactgcct taccatacac
    12841 tgggcgtaca taagtacgaa gcgatgggac aggaatacaa gatgaaaggg gtaaaagaaa
    12901 atacccccga acagcttgaa aaagctgcgg aggtattcaa agagtatttc actacggtgg
    12961 tagttaatta atggagaatt ctccaatgac ctcaaagcaa gggcattctt taatccgttc
    13021 ccaaggatct acgatcccat tatagttggt gtcgggactt aaatcccgat gccctactac
    13081 tttagcttcc ggataacgct gcaacaattc gtgtaccaag cgatgtagcg cctccttctg
    13141 acggggtgta cgcgtatccg cagcttttcc attctcatcc agaccgccct cataacatac
    13201 acctaagctg atcgcattat agccacgtgc atgagctccg accgtatctt tatcccgcat
    13261 cggctcaatc tcgcccgact tgcgtatata ataatgatac ccccagcacg aaaagccacg
    13321 ataacggtga gccgtatcca catcctttgc cgtaaagtcg caatcgacac gggtggcgga
    13381 acaatggatc acaatcagac taatctttct catgttcctt ttccctttcc gtcgttttca
    13441 ctttgcacac ctccttacaa gtagtatgat agcgcacttc tctcaccacc ctgtcccgct
    13501 ttctctttcc gaagaaagga atcagataca tgatcacatc taaaatccga cttactattt
    13561 ctttcatctt atcaaaatat taatggaagt tattctaatt cgttattacc ttgacccgtc
    13621 tgccaattat accgtagggt ccggagcctc ttcatcaccg gagccatcac caccggaatc
    13681 cggattcttg tcagggtctt ctcccccgcc atcgcctgca cccgcctgcg ccaccgcacg
    13741 agtctgcact tgctgataac tcagaatctt catcaactcc gccagcgtct taccggggcg
    13801 gaaaataaga tgcgccccct taatcattga accggaaaat tccttgaccg atgccgcacc
    13861 ttcactgttg agtcctatct gcaaactgcc caaatcgccc agtctcgcaa ttcttcctgc
    13921 cttcaacgca cgcttcactt cgtaaagaat acccgaaata gccgcacgta catccgtttc
    13981 cgtacaagta gaacgactgg tgatcgcttc gcacaactct tcaaagtcca actctcccga
    14041 cgcctgcgcc tgtgcataat actttgccgg ttcgctcttt tttgcaggat tcttgcgcgg
    14101 caccactgaa taagatactg tcattgccat aataaaataa ttttaaagtt tataatacat
    14161 aggatgcatc cccttcttgt taacagcaca aagataagga tagccggaca agccatattc
    14221 cccaacgaag tttcttgatt cccaacgaat aaaaacgaag tcaaaccttt gaataacaag
    14281 gaattttatg taactttata gcataaaaca agaagaaaac atcatgaatt acaaagaaga
    14341 ttctttcctt atccgcacct ataccaaagc ggaactggct cacctttaca atccccatgt
    14401 ctgcctcaaa gttgctttac aaatacttcg tcgttggatt atttacaacc tccctctcct
    14461 gcacgaactc gaacaggaag gctaccgcgc acgcaaccgt ctcctttcgc cgaaacaagt
    14521 ggcaactatc atacactttt tgggcgaacc gtagtaactt attgccattt tatacaaagt
    14581 tcctttacac atttccgcaa agaagttcct ttgcatcgac aaacaataat caaaataaaa
    14641 atgaaacatt tcaccatatt tcaaggtttc tactacgcaa tagcagagat gaccgaagaa
    14701 gaaatagtgt ccactatcgg cagttttacc taccgggaaa aagtcgaaga aatacgccgc
    14761 atctttgcag agcaaggaga aaaggctgcc aatgagaaga aaaaagaatt gccggcaatc
    14821 gccttctccg ccagctaccg aggaaggcgt accaaagtga acctcgtcaa atatctggga
    14881 cacatcgtga tagacatcga ccacctcagc aaagaagaat tggcacgcat cctccctatc
    14941 atcaagagat gcgattacac ccgcatcgcc tttatcagcc ccaaagggat gggcgtgaaa
    15001 atcatagtac gcgcatgcca tccggatgag acattgcccg aaacccttca ggaaatagaa
    15061 gacttccatc atgcagctta caccagactc gtttcttttt acaccgaact ctgtcagata
    15121 gaaatcgaca cctccggtca ggatgtggca cgcacttgtc tgttctctta cgatccggag
    15181 atttatttca atccgaacgc tgacgctttt cttgtagatc aacctcaggc atcctacaag
    15241 gtttcaaatc gtaaaaatct ctccggcagt aaacaacaga ctcctccgga cggccccccg
    15301 acgaatgaag acacagcgct caacgcccat tccgccaacg cttctctggt gctgacttta
    15361 acctactatc acaacaagtc cgaaaaatac atagtgggca accggaacaa ttatctgcac
    15421 catctctcat gtaccttcaa tcgctacggc attccgcagg aggaagcatc cgcctttatc
    15481 aaaagccagt ttacagactt tccggcggac gagacagcct ctttgatcaa tagcgcctac
    15541 gctcataccg acgaatttaa tacctgtaag ctaaatggca cgcagaaacg aatattacgg
    15601 atagagcaat atatcagcga gcactacgaa acacgctaca acgaagtgct gcatatcatg
    15661 gaatatcgca gaaggcatcc cgacaccgag aaaccggagc ctttccgcat cttggatgag
    15721 atgatggaaa acagtatctg gatagaaatc aacgaactgg gatatgcctg cactgtcaaa
    15781 acaatcgaaa atctgattta ctccgatttc agccagtcgt atcatcccat tcgcgagtat
    15841 tttgaattac tgcccgaatg ggacggaacc gactatatcc gtatcctggc ggatagtgtc
    15901 cagacgagtc atcaggagtt ttgggcggaa tgcctggaac gttatctggt ggcgatgtgc
    15961 gcagcggcta ctcaagagaa tattgtcaat cacacggtac ttctgctatg cagcgagata
    16021 cagaacatag gaaagactac ctttatcaat aatctcctgc ctcccgaact gcgtgcttat
    16081 ctctctaccg gactaatcaa ttcgaacaat aaagatgatt tagccaaaat aacgcaggcc
    16141 atgctgatca atctcgacga gtttgaaggg atgagcggtc gggaactgaa tgcattcaaa
    16201 gatttggtaa cgcgcaaagt gatcagtttc cgtctgcctt atgcacgccg ttcgcaaaac
    16261 ttccctcata cggcctcttt tgcaggaacc tgcaattatc aggaagtgct tcacgacacg
    16321 acaggcaacc ggcgtttcct ttgttttcat ccttattcca tccaatttat taccatcaat
    16381 tatgcgcagc tctatgctca gatcaaatat ctgctgaata agccgggata tcaatactgg
    16441 ttcacgcaag cggacaatga acggcttgaa gagaataacg aggctttcat ctttcattca
    16501 ccggaagaag aaatggttct tacgcatatc cgcaagccgg aacgtttcga gaaggtttat
    16561 tatctgactg tcagtgagat tgcggaacta atacgtgagc gtaccggtta tcagtattcc
    16621 atcggatcaa aaatacagtt ggggaaggtg atgactaagc accattttga atctaaaaaa
    16681 ggaaataacg ggcgccgata tgccgtattt attatagata tcgagcaggt aaaatcaaac
    16741 aggctgtatg aatagaagcg ggaaagcctt gtgaatatag caaaatgcag agtcatcttg
    16801 acagatactc tgcatttatt gtttttacaa aatcattgaa aattcgattt tacagcctaa
    16861 cgcattcatt atacgataga aagtagatac tttaggctct gtctgaccac tttctactct
    16921 tgaaatataa gaacggtcag agccgatacg ccgggctaat tcagcctgag tgattttagc
    16981 cttttagatc ggaagagcgt cgtgtaggga annnnnnnnn nctcgataat ctgtcctgta
    17041 taaaaggcgt aggccttttc ttctgcctct gcacgagaag ctgttccttc cttaccaaaa
    17101 cgctcatcta ttaatgcact gacattaaag aattcctcat ttgtttttgc ttccataata
    17161 ctcctttctt aatatctttg ctttatcaat ttctttcttt ggtgtttttt cggttttctt
    17221 ttgaaaaccg ttaaacagaa tcacaatacg cccttcgtcg aaacaaaaga atattctata
    17281 tatattgctt tggtactcga tacgaagttc ataaagtcct tcttctatca accgcataaa
    17341 tttcaaaggt attctgtctt gtgtctgcaa taacattagc acatacaata tcttatcttg
    17401 ggtgccagca tctaaatttt caaagaattc tttgaagtat cctttatatg ctattatttc
    17461 tcttttcata acgcaaatat aaggaatgtt gttcaactat acaacacatt tcctcgtttt
    17521 atattatttt tcatcatctt cacccccaaa agtgagagga gtgagagagg aattgaaact
    17581 ttttctattt tatttcttta tttctacttt ctatatttct ctaaaaaaaa atacgaatgt
    17641 t
//
