LOCUS       c00466_gnlPro..         2936 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GDFPIDOG_466.
ACCESSION   c00466_gnlPro..
VERSION     c00466_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 13:50:54
            Original ID  :: gnl|Prokka|GDFPIDOG_466
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 2936
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..987)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg466_1"
                     /sec_met_domain="IlvN (E-value: 5.6e-48, bitscore: 150.7,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.3e-36, bitscore: 114.2,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQMNFGGVVENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRQGKTYDKAVEDGWVPGETLFGIEEACDKATIIMCLLSDAAVMS
                     VWPTMKPYLTAGKALYFSHGFAITWNDRTGVVPPADIDVIMVAPKGSGTSLRSMFLEGR
                     GLNSSFAIYQDATGKAMDRTLALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMG
                     PFHDAIKPVVEKLYANVKCGNEAQISIDSNSKPDYREKLEAELKALRE"
     protocluster    1..2936
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:2935]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1..2935
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..2936
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..2936
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             complement(1037..1762)
                     /locus_tag="ctg466_2"
                     /transl_table=11
                     /translation="MEKVGLFHFVAEPYLMDFRGRVTLPMIGNYLIHAASSHAGERGFG
                     FNDMSERHTAWVLSRLAIEMKEYPTAFDKINLYTWIDEVGRLFTSRCFELADENGKTFG
                     FARSIWAAIDVETRRPTLLDIEALGKYIDERPCPIEKPGKIMPAENKAEGIPYSIKYSD
                     LDINGHFNSVKYIEHLLDLFDIDQFKTREIGRLEIAYQSEGKQGMPLTLHKAESAPDKQ
                     DMAICHEGKAICRAAVTWR"
     CDS             complement(1769..2323)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg466_3"
                     /sec_met_domain="ALS_ss_C (E-value: 1e-17, bitscore: 52.4,
                     seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKKLYTVIIFSENIVGLLNQITIIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDMIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEGLIRKYNARILEMNEACVVLEKSGHYDETQALFNELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLADMERKLHEKQQ"
     CDS             complement(2339..2935)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg466_4"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.1e-52, bitscore:
                     165.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="QLKMGEVVRKVSEATGNDAVLVTDVGQNQMMGVRYFKYKQTRSVV
                     TSGGLGTMGFGLPAAMGAKFGAPDRTVCFFTGDGGMQMTIQELGTIMQEKLNVKIIILN
                     NNFLGMVRQWQELFFHERYSNTIMENPDFVAIAKAYGIAGRAVEKREELDDAIAEMLNH
                     DGAYVLVANVETCGMVYPMVPAGGSVTNMIMGDEK"
ORIGIN
        1 ctcgcgcaat gccttcaatt cagcctccaa tttctcacga taatccggct tagagtttga
       61 gtcgatagag atctgagcct cgttaccgca ttttacgttt gcgtacaatt tctcgacaac
      121 cggcttgatt gcgtcgtgga acggacccat ccagtccaaa gcgccacgct gggcggtagt
      181 agagcagttc gcgtacatcc agtccatacc attcttggcg aataaaggca tcaaggattg
      241 agtcaactcc tcgaccgtct cgttgaaagc ctcggaagga gtatgtccat tctcgcgcaa
      301 tacctcatac tgggccaaca acaaaccttg gatagcgccc atcaaggaac cacgctcacc
      361 agtcaaatcg gaagtagcct cacggatgaa agtcgtctcg aacaagtagc cggaaccgat
      421 accgataccc aacgccaacg tacgatccat cgccttgcca gtagcgtctt gatagatagc
      481 gaaagaagag ttcaagccac gaccctcaag gaacatggaa cgcaaagacg taccagaccc
      541 cttcggagcg accatgatca cgtcaatatc cgcgggagga acaacgcccg tacgatcgtt
      601 ccaagtgatc gcaaaaccat gagagaaata cagggccttg ccagctgtca aataaggctt
      661 catcgtaggc catacagaca ttacggcagc gtcggacaac aagcacatga tgatcgtggc
      721 cttgtcgcaa gcctcctcga taccgaacag agtctcaccc ggaacccatc cgtcctcaac
      781 cgctttatcg taagtcttac cttggcgctg gccaacgatt acgttgaagc cattgtcacg
      841 aaggttcaat gactgtcccg gtccctgtac gccatagccg ataacagcga ttgtctcatc
      901 ttttaatatc tctcttgcct tttccaacgg aaattcctcg cgggtcatta cattctctac
      961 aacaccgcca aaattcattt gtgccatttt ctttttaact attaatgttt aaaaacctat
     1021 ttatgtatct cttttattat ctccaagtaa ccgccgcacg acagatcgcc tttccctcat
     1081 ggcaaatagc catgtcttgc ttatcgggag cggactccgc cttatgaagc gtaagcggca
     1141 taccttgttt accctcggat tggtaggcga tctccagacg gccgatctca cgggtcttga
     1201 actgatcgat atcgaacaaa tccagcaggt gctcgatata cttcacgcta ttgaagtgac
     1261 cgttgatatc caagtcgctg tatttgatcg aatacgggat tccctccgcc ttattctccg
     1321 ccggcatgat cttgcccggc ttctcgatcg ggcacggacg ctcgtcgata tatttgccca
     1381 atgcctctat atccaataag gtaggacggc gggtctccac gtcgatagcc gcccaaatag
     1441 aacgggcgaa tccaaaggtt ttcccattct catccgccag ctcgaaacaa cgactggtga
     1501 agaggcgtcc gacctcatcg atccaagtgt atagattaat cttatcgaag gcggtaggat
     1561 attccttcat ctcgatagcc agacgggaca acacccaagc cgtatgacgc tccgacatat
     1621 cattgaaacc gaacccacgc tctccggcat ggctggaagc ggcgtgaatc aaatagttac
     1681 caatcatagg gagcgttaca cgtcccctga aatccatcaa atacggctcc gccacgaaat
     1741 gaaataatcc tactttctcc atatcttatt attgttgctt ttcatgtaac tttcgctcca
     1801 tatcggccaa catatcgctc aagcgctcca ccttgctctt cgtgatagcc acacgtccgg
     1861 agcggatgaa ttgcaggaca ccgatcgtct cgctcaactc attgaacaag gcttgtgtct
     1921 cgtcatagtg gccactcttc tccaacacca cgcaggcctc gttcatctcc aagatacgag
     1981 cgttgtattt acggatcaat ccctccacgg ttcccatctt gatgaaaagc tcggtactta
     2041 gcttataaag ggcgatctct tgataaacca gatcctcatc cgtattataa taagccttca
     2101 agatatccac acgtttatcg atctgtttca ccaccttatc gatcatatcc tcatcggcga
     2161 aggtcgtgat cgtaaactta tggatgccct tgatagcgga cggagagacg gacagagtct
     2221 cgatgttcag ctgtcggcgt gtaaagataa tcgttatctg gttcaaaaga cctacgatat
     2281 tctctgaaaa gataataacg gtatataatt tctttgttgt catagcttca tctcctcctt
     2341 atttctcgtc tcccataatc atgtttgtca cgcttccccc ggcaggaacc atcggatata
     2401 ccattccgca agtctccacg ttagcgacca acacgtaagc gccgtcgtgg tttagcatct
     2461 cggcgatagc gtcgtccaat tcctcccgct tttcaacggc acggccagcg ataccatagg
     2521 ctttagcgat cgccacgaaa tccggattct ccatgatggt gtttgaataa cgctcgtgga
     2581 agaacaattc ttgccactga cgtaccatac ctaagaagtt attattaaga atgataatct
     2641 tcacgttcag tttctcctgc atgatggtac ccaattcctg aatcgtcatc tgcatacccc
     2701 catcaccggt aaagaagcag accgtacggt ccggagcccc gaacttagcg cccatagcgg
     2761 ccggcagacc aaatcccatc gtacctaaac ctccggaagt caccacgcta cgggtttgtt
     2821 tatatttgaa atagcggaca cccatcatct ggttctgccc aacgtcggtc accaatacag
     2881 cgtcgttacc ggtcgcctcg gaaaccttac ggactacctc gcccattttc agttgg
//
