LOCUS       c00067_gnlPro..        15314 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FIMJPNFJ_67.
ACCESSION   c00067_gnlPro..
VERSION     c00067_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 09:14:37
            Original ID  :: gnl|Prokka|FIMJPNFJ_67
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15314
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15314
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[4825:7907]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      4826..7907
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..15314
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15314
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             2..214
                     /locus_tag="ctg67_1"
                     /transl_table=11
                     /translation="YTRTYTLSLHDALPISRPVYGAKVGSTAFQIGAGLSVPVGTQGVI
                     FVDGNADIRSGSSSINGSIGYRYNF"
     CDS             complement(336..746)
                     /locus_tag="ctg67_2"
                     /transl_table=11
                     /translation="MTDHYYTSETENVGQFRCETTFIPSNVTFATDLPASFEGRAEFPS
                     PGVLLGSTLASCMMSLVSVVAARKGVDLKGMRVLARAAESSKGIEKIELKAIMPLEGSH
                     PLRAMLEKTALSCPVRQALRPDLETPIEWEWK"
     CDS             complement(945..2108)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg67_3"
                     /sec_met_domain="Abhydrolase_1 (E-value: 5.5e-30, bitscore:
                     94.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLPAVQTKFLDLPNSFSLRNGATLDKVRVAYEQYGTLTPNKDNA
                     ILLFHALSGSQHAYGYNPEVPGIGSLWKPENHEGWWNSIIGPGKPLDTNRFCIICANYL
                     GGCYGTTGPATPCPADGQPYGSRFPHVEAADQARLQALLLDSLGIERVHLMGPSVGGLI
                     ALSFACQFPERVRSFISIGSGYRASIEHRLSLFEQILAIELDPDFQGGDYYRGLAPKKG
                     LAFARIIGHKSFVYQEGLEQRARKEVGGNYGLLTWMTPTRSTQSYMLHQGTKFAERFDA
                     NAYIRIADMWAEFDIRDHTPDGTFQTALEGFRRAGIPALIFSIDTDCCFRPAEQQDFAA
                     QLEAAHIPTEFHTIASTKGHDSFLLEPELYAEPIRRILEARKPKGTA"
     CDS             complement(2195..2497)
                     /locus_tag="ctg67_4"
                     /transl_table=11
                     /translation="MLYCIFLIKASLRRRHLTFGKEMTLQFLTKRYISSPEPNTKPELY
                     TMKVLSSLASMKRRHADCQIVKRKGTLYVICKSNPKFKARQGATAGTRLSKKGVK"
     CDS             2647..3621
                     /locus_tag="ctg67_5"
                     /transl_table=11
                     /translation="MTDSSSPDSSPASRNTFAHHLGMKGFLLMEGLLKLVGMKTLYRLG
                     RAAGAVAWHLLPQRRNIVERNLRIVLDPALRGKELQKLSRENFKRTIANFLCSAKTATL
                     TDEQLKHCVTVGGHEQFAAPVLEGRGQVCAIAHSGNWEALARIRAFYPEVERYGSMYRQ
                     FDNPLMEEYVYQRRTERGTQMFSKEGGIKAPMKMLKEGGALGVLSDQFVWEGVYVPFFG
                     KVTGTTPLPALLRKRAGADMVAIAVRTDAPGHWIADMGNVVDFSRSDGSLAGDTIEVNR
                     GLETLIRESVLDVFWMHHRWKSVDXXXXPRRIKKRLRSWKIWS"
     CDS             3612..4577
                     /locus_tag="ctg67_6"
                     /transl_table=11
                     /translation="MELKPYRILVAVPRALDEALATVPLIRALKTVRCDMQVNIVCPSA
                     QLGIWKTVPEVTHVLPHDSLKQLREALAADEFYNDGPLDLGVMLDGDMETLKALEPYGP
                     MMFSGLDTHPGARKYKFRVKAPVLRAAPPAHRVQLYLQLGGLHGLDAATPSLFPVKKAA
                     PAEDAPILIAPFSRLGSASEWSWEQWRELVSLLPGRTVLAALEEDRERAASLAEHLNVE
                     LAVGAPEALFPVMDGAAAAVAVDGDLPSLCSFRGLPVVTLFSTRLPDVYRPMGTFNRSL
                     YSHQCCSPCFRKECDRDVPCNRHIAVRDVLEALREISGKE"
     CDS             complement(4826..5623)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 53.6;
                     E-value: 9.5e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg67_7"
                     /sec_met_domain="Radical_SAM (E-value: 1.7e-30, bitscore:
                     96.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQVFPQNHDPDGESSVTGLVHSVESCGTVDGPGIRFVLFLSGCS
                     LRCRYCHNPDTSYVRRGRLRSADDVLKEIARYRDFLQAAGGGVTLSGGDPLFQPDFAGA
                     VLKGCRKLGLHTCLDTSGHLGVNAGEEMLADTDLVLLDIKAWNPKRYRALTGGELHPTL
                     EFAERLASLRKPVWLRYVLVPGVTDXXXXADNLEEIEELSRHAALLGNVERVDVLPFHQ
                     LGRFKWDELKLDYTLKDVPEASAELAEQVRGIFRQGGFPDCVH"
     CDS             complement(5640..7907)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg67_8"
                     /sec_met_domain="Gly_radical (E-value: 1.7e-45, bitscore:
                     144.0, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 7.3e-282, bitscore:
                     926.0, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISIVKDLKESTALPQEWQGFKPGTWTESIDVRDFIQHNYTPYSG
                     NEEFLSGPSQRTLRLWDELKVLLKREIDNGGVLDADEEVVSSITSHKPGYIDKELEVVV
                     GLQTDAPLKRALMPFGGLRMAQQALESYGFKMCEKTADIFKKIRKTHNEGVFDAYTSDI
                     RAARSAGIITGLPDAYGRGRIIGDYRRVALYGTDKLIAERRKDLKNREHSPLTDELIRL
                     REEMSEQIRALEELAQLGASYGCDLTRPAANAREAVQWTYLGYLAAVKEQNGAAMSLGR
                     VSTFFDIYFTRDLEQGLITEEEVQEIIDQFVMKLRIVRFIRTPDYNNLFSGDPTWVTES
                     IGGMGEDGRTLVTRSSFRMLQTLYNLGPAPEPNLTVLWSRNLPEAFKSFCAKVSIETSS
                     VQYENDDLMRPHWGDDYGIACCVSAMRIGKQMQFFGARANLAKCLLYALNGGVDELKGK
                     QVAPPSPRYTEEILNYDEVMALYDKMQDWLAKTYIDALNIIHYMHDKYCYERIEMALHD
                     PEILRTMATGIAGLSVAADSLSAIKYATVKAIRNEEGLIVDFKTEGEFPCYGNNDPRVD
                     DIACSLVSNFMEKLRRLHTYRNSLPTQSILTITSNVVYGKKTGNTPDGRRAGEPFAPGA
                     NPMHGRDRNGAVASMLSVAKLSYDDSLDGISYTFSIVPQALGKEERERRVKLVSLLDAY
                     FAATGHHINVNVLERKTLLDAMDHPEKYPQLTIRVSGYAVNFIKLTREQQQEVINRTFH
                     TR"
     CDS             8188..8970
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg67_9"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 5.8e-24, bitscore:
                     75.4, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSYACLCLLLAGVFCVACFSGACADELPPTLKPQVNPRAVYDWK
                     KRHEAVMERNRTVKPEYVVFGDSITHRWGGEPSGDNRALGTGKTAWHSLFSSHAVTNMG
                     FGSDYVDNAYYRLQLGELDGISPRVIIVLLGTNNLGGRKDAPRACADNLKAFVSLARRK
                     CPSSKILLLGILPREGKKLAPLIRETNKMISGLADGNSVFFANPGEEFLGEDGVSPKPG
                     LLEDGLHPSARGYDILGKSLSVLLKKMDDKYGKLPAPR"
     CDS             9193..9981
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg67_10"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 9.8e-24, bitscore:
                     74.7, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFLSYMLAILLGSSSLAFSAPSIPASALPATLKPEPHQRDPYDW
                     NARHEAVKKRNRAVKPEYVMIGDSITHHWGGEPSGDGKNTGSGSWEKLFGPHAATNMGF
                     GFDYVDNAYYRVQNGELDGISPRVIIVLLGTNNLGHRKDTPQACADNIRAFVRLVRRKC
                     PSSKILLLGVLPRKEKNLAEPVKQTNRLLAELHNGKDIFFADPGKALLSADGASPQNEF
                     MKDVVHPNARGYEVLEKELAVLLKKLDAKYRGGKQAGKHS"
     CDS             10066..11853
                     /locus_tag="ctg67_11"
                     /transl_table=11
                     /translation="MKNLLFALLTGSFCCCYAQQKAAPVPEPEVVATPPADAGRGLIRV
                     DSREIRHYSGTRKEPDYLVSRDNGKTWEMKAAPAGYPPNYGGIPKESPAIVRNPLTREF
                     IRVQPIGGFVFLSRGGLDGKWLAVTNDGKLEEDWKDPEKRKNLKKLGGIMRTPVFVNKG
                     RRVIVPFHNMGGGTKFHISDDGGLTWHVSRNGVTSPRHEARPPHQGVRWFNNAVEATVL
                     EMKDGTLWALARTSQDQAWQAFSKDYGETWSKPEPSRFFGTLTMNTLGRLDDGTIVSLW
                     TNTMALPENATAGNGTWEDVFTNRDSHHIAMSGDEGKTWYGFREIILDEHRNHPGYATL
                     DGPEDRGKHQSEMVQLDKNRILISLGQHKNHRRLVIVDRRWVGAKTRATQTGKDLDSQW
                     TIHTYIPQKKGHCSYNRKPSAELVQDPSGGTKKVLQIKRLDDPELVNEKSNVDYRNGGA
                     TWNFPNGTTGLVKFRFRVADGEQADDSGLQVSLTDRLFNACDSTTKDYALFTFPIRLRP
                     APHLLLGMKKVPFSPGAWHEISLLWQGGQAVVSLDGKKAGTLKMANKSPNGVSYIHFIS
                     TGSQPDAGILLDTVNARVK"
     CDS             complement(11867..13228)
                     /locus_tag="ctg67_12"
                     /transl_table=11
                     /translation="MIHMTLRKKTLWFLGALSFFASLAAAFAVFWLNRNDSSPAEWNFN
                     PIWTKAEKEQILTAANFTAHRSPERFIYRGLSLNSRHIDWHMFSEVSMRQYMKDEIRER
                     LQMIRDTAESADGRCITPSHETLLHLAAGLGEVQLLNRLLQRHADPNVQIILPQQAFPS
                     IPDSEQGNTPLTYACQPGMDDSTPLPVHNRLSCLNLLIQYGADVNKPGPLGWPPLIITC
                     VAGIGGAPYEEAALFLLKCGADISLQPELKGKKTSLLTWAAAAGYPLLVRKLCEAGYDP
                     NFRGEMAPPLLSLNLNTPNAALQIAHILLEYGADVNAAMPASTTLPETAGDTALLNLCR
                     QLAFIDVSCLPQIRDLVNLFIKEGADVNHQNAAGETPLMACCRGMLLGDDSLDRLKLGI
                     ARLLLDHHANPSLKDKYGRTALQRIGNRSNEHLQMVLKYLPELSAPPLPKKENH"
     CDS             13707..14606
                     /locus_tag="ctg67_13"
                     /transl_table=11
                     /translation="MLSEAALALEVRINDDSGSVMDSVKLIASDMDGTLLNGKGELDPA
                     FFPLFRELELRGIRFAAASGRQYDGLLRTFAPVADRMLFIAENGAYAAAGRKEWLLLDM
                     DHETVAGLIAGIRRIEGTCIVLAGRDSAYIEDKQPEFVREARKYYTRCQEVGDLLDVRG
                     DKLLKIAVYDFLGAGENSFPRLKHLEHGFQVAVSGEKWMDISRKGANKGAALELIQRKL
                     GVSPEETMVFGDQMNDAPMMRQARFSYAMANAVPEIRSMAAFEAPSNEENGVMQVLGKM
                     LDAHSPQGRSGNCRKPRF"
     CDS             14642..14824
                     /locus_tag="ctg67_14"
                     /transl_table=11
                     /translation="MLLSDFFNMLAMAVFACIGGVFLGMGFLLLKLAGIFFGILAGCII
                     LMEAAGRWISHLMGA"
     CDS             15224..15313
                     /locus_tag="ctg67_15"
                     /transl_table=11
                     /translation="MNQEFFSVLVQVAAALGLAGMILLLSILMG"
ORIGIN
        1 ctacaccagg acgtacactc tttccctaca cgacgctctt ccgatctcgc gtccggtgta
       61 tggcgccaag gtcggaagca cggccttcca gattggcgcg gggctgagcg ttcccgtggg
      121 cacccagggc gtcatttttg tggacggcaa cgcggatatc cgcagcggct ccagctccat
      181 caacgggagt atcggctacc gctacaactt ctaaaggaaa aaacgtcggc cgattggaaa
      241 gccgctgcgg atgattccgc agcggctttt ttcatgaatg ggcgggattt ctttaaggat
      301 aacttcaagc ttgggttgac gtccctgatg gctgcttact tccattccca ttcaatgggc
      361 gtttccagat caggccgcag cgcctggcgc acagggcagg acaaggcggt tttttccagc
      421 atggcgcgga gagggtggct gccttccagg ggcatgattg ccttcagttc aattttttca
      481 attcccttgg atgattccgc cgcacgcgcc agaacgcgca tgcctttcaa atccactcct
      541 tttctggccg cgaccacgga aaccaggctc atcatgcagg aggcgagcgt ggaaccgagc
      601 aaaactccgg gggaggggaa ttctgcgcgg ccttcaaaag aagcgggcag gtccgtggca
      661 aacgtaacgt tggaaggaat aaaggtggtt tcgcagcgga attgtccgac gttctccgtt
      721 tcggaggtgt aataatgatc agtcatgaag gtgtgacagc gaaaaccctg ttcgggttca
      781 tccggttcag gttattttca cgttgaagag ccgtgaagtt ccgctttgca gggaacctgg
      841 ccgttccttc atgacatggt tgatttttcc ctcttgcttc cggttcccgg catcacttct
      901 ttttaagcgt tgctccgccg tgtcttcttg cggcgggaaa aagcttacgc cgtccccttc
      961 ggcttccttg cctccagaat gcgccggatg ggttccgcat aaagttccgg ctccagcagg
     1021 aaggaatcgt gtcccttggt ggaagcgatg gtatggaact ccgtgggaat atgggcggct
     1081 tcaagctgcg ccgcgaaatc ctgctgttcc gccgggcgga aacagcagtc tgtatcaatg
     1141 gaaaagataa gcgcgggaat ccctgcgcgg cggaagcctt ccagggcagt ttgaaatgtt
     1201 ccgtccgggg tgtggtcgcg gatgtcgaac tccgcccaca tatccgcaat acggatatag
     1261 gcgttggcgt caaagcgctc cgcgaacttg gttccctggt gaagcatgta gctttgcgtg
     1321 ctgcgggtgg gggtcatcca cgtgagcagg ccgtagttgc ctcccacctc ttttctggcg
     1381 cgctgttcca gcccctcctg gtaaacaaat gatttgtggc cgatgatacg ggcgaacgcc
     1441 agcccttttt tgggcgccag tccccggtag taatccccgc cttggaaatc cgggtcaagc
     1501 tcaatggcca ggatttgttc aaacagggac aggcggtgtt cgatggaagc ccggtaaccg
     1561 gagccgatgg agatgaagct ccggacccgt tccgggaact ggcacgcgaa gctgagggcg
     1621 atcaggccgc ccacggaggg gcccataaga tgaacgcgtt ctatgcccag gctgtccagc
     1681 agaagggcct ggagacgtgc ctggtctgcg gcctccacat gcgggaagcg ggagccgtag
     1741 ggctggccgt ccgcagggca gggggtagcg gggcctgtgg tgccgtagca gcctcccagg
     1801 taattggcgc agatgatgca gaagcggttt gtgtccagcg gcttgccggg gccgatgatg
     1861 ctgttccacc agccctcgtg gttttccggt ttccagaggg aaccgatgcc cgggacttcc
     1921 ggattgtaac cgtaggcgtg ctggctgccg gaaagagcat ggaacagcag gatggcgttg
     1981 tctttattcg gcgtcagggt tccgtattgt tcgtaggcga cgcgaacctt gtccagcgta
     2041 gctccatttc tcagggagaa ggagttggga agatccagga atttggtttg gacggcagga
     2101 agctgcatgg atgtacggaa aggggcttgg tcagcaaaaa aagaccggca cccggcgggc
     2161 ggcggtcttc ttgaaatctg tgctgggcca gggattactt aacgcccttt ttggaaaggc
     2221 gcgtgcctgc cgtagcgccc tggcgggcct tgaacttggg attgctcttg cagatcacat
     2281 acagcgtgcc cttgcgcttc acgatttggc agtctgcgtg gcggcgcttc atagaggcta
     2341 aggaagaaag aactttcatg gtgtataact ccggtttggt gttcggttcg ggagacgaaa
     2401 tataccgttt agttaagaat tgtaaagtca tttctttgcc aaaagtaaga tgccgtctcc
     2461 gcagagatgc ttttatgagg aagatgcagt aaagcatggg atggctttgg attccgcgcc
     2521 ggcggaaaaa tttagggaag acgtcattta gccgggaaaa taaaatgcgg gaagggatct
     2581 ctgccggggg aataaagggt ttgtggaccg gaggggattc gtataacatc ttttccggtt
     2641 ttccttatga ctgattcttc ctctcctgat tcctccccgg cttcccggaa tacgtttgcc
     2701 catcatttgg gaatgaaagg gtttctgctc atggaagggc tgttgaagct cgtgggcatg
     2761 aaaacgctgt accggctggg gcgcgcggca ggggccgtgg cgtggcatct gcttccccag
     2821 cgccggaaca ttgtggaaag gaatctgcgc atcgttttgg atccggccct gcgcggaaag
     2881 gaactgcaga aattaagccg ggaaaatttc aaaaggacca ttgccaattt tttgtgttcc
     2941 gcgaagacgg ccaccctgac ggatgagcag ttgaagcatt gcgtgacggt cggagggcac
     3001 gaacagtttg ccgcgcctgt gctggaaggg cgcgggcagg tttgcgccat agcccactcc
     3061 ggcaactggg aggcgctggc gagaatacgc gcattttacc cggaggtgga gcgttacggg
     3121 tccatgtacc gccagtttga caatccgctg atggaggaat acgtgtacca gcggcgcacg
     3181 gaacgtggaa ctcagatgtt ctccaaggag ggaggcatca aggctcccat gaaaatgctc
     3241 aaggaagggg gagccctggg cgtgctgagc gaccagttcg tatgggaggg ggtgtatgtc
     3301 ccctttttcg gcaaggtgac cggcacgact ccgctgcccg ctctgctgag aaaaagggct
     3361 ggcgcggaca tggtggccat agcggtgcgc acggatgctc ccggccactg gatagcggat
     3421 atggggaatg tggtggattt ttccaggtcg gacggctctc tggcggggga cacgattgaa
     3481 gtgaacaggg ggctggaaac attgatccgg gaatccgtgc tggatgtgtt ctggatgcac
     3541 catcgctgga aatccgttga cnnnnnnnnn ntgccccgca ggataaaaaa acggctgcgc
     3601 tcctggaaaa tatggagctg aagccgtacc gcattctggt agccgttccc agggcgctgg
     3661 atgaagccct ggcgactgtt cccctgattc gagctttgaa aaccgtccgg tgcgacatgc
     3721 aggtgaacat cgtctgcccg tctgcccagc tggggatatg gaagacggtg ccggaagtca
     3781 cccatgtgct gccgcacgac tccctgaagc agcttcggga agctttggca gcagatgaat
     3841 tttacaatga cggaccgctg gatctgggcg tcatgctgga tggagatatg gaaaccctga
     3901 aagcgctgga accgtatggc cccatgatgt tttccgggct ggacacgcat cccggtgccc
     3961 ggaagtacaa gttccgggta aaggcccccg tcctgcgcgc cgcccccccg gcgcaccggg
     4021 tgcagcttta tctgcaattg ggggggctgc atgggctgga cgccgccacc ccgtctttgt
     4081 tccctgtgaa aaaagcggcc ccggcggaag atgcccccat tttaatcgct ccgttttccc
     4141 gcctggggag cgccagtgaa tggagctggg agcagtggag ggagctggtt tcccttctgc
     4201 cgggacggac ggtgctggcg gctctggaag aagaccggga gcgcgccgcg tccctggcgg
     4261 aacatttgaa tgtggagctg gcggtgggtg cgccggaagc tctctttccc gtcatggacg
     4321 gcgctgcggc ggcagtagcc gtggatggcg acttgccgtc cctctgttct ttccgggggc
     4381 ttccggtggt gactctgttt tccacccggc ttccggatgt ttaccgccct atgggcacat
     4441 tcaaccgttc cctttacagc caccagtgct gttctccctg cttccggaag gaatgtgacc
     4501 gggatgttcc ctgcaaccgc cacattgccg tgcgggacgt actggaagcc ttgcgggaaa
     4561 tttccgggaa agaataatct gggaagggac ggaatgccgt cccccggcgt tggcggaaaa
     4621 aacggcggga atgctgccgt tgccgtaaag aatgatgaaa taacgaaagg aattgcggaa
     4681 atgccgtatt ccggagcaat tccagaaatg cgtcttcctt tttgcatgga ttctgcagtg
     4741 gaggggagag ggcccctcat ccggaagagg gggatgcctg cgtccggttt gctgcggttg
     4801 gtggcgccaa agcgcgaaaa tccggttaat gcacgcaatc cggaaagccg ccctgccgga
     4861 aaatgccgcg gacctgttcc gccagttctg cggacgcttc cgggacgtcc ttcaaggtat
     4921 agtccagctt caattcatcc catttgaatc tccccagctg gtggaaaggg agcacgtcca
     4981 cgcgttccac gttgcccaga agcgccgcat ggcgggagag ttcctcaatt tcttccagat
     5041 tgtccgcnnn nnnnnnnttg tccgtaacgc caggtaccag cacatacctc agccacacgg
     5101 gcttgcggag ggaggccagg cgttccgcaa actccagtgt agggtgcagt tccccgcctg
     5161 tcagggcgcg ataccgtttc ggattccatg ccttgatatc cagcaggacc agatccgtat
     5221 ccgccagcat ttcttcgccc gcattcacgc ccagatggcc ggaggtgtcc aggcaggtgt
     5281 gcaggcccag tttccggcag cctttcagca cggcaccggc aaaatccggc tggaagaggg
     5341 ggtccccgcc ggagagggtg acgccgccgc ccgccgcctg caaaaaatcc cggtaacggg
     5401 ctatttcctt gaggacatca tctgcgctcc tgagccggcc cctccgcacg taggaggtat
     5461 ccggattatg gcagtagcgg cagcgcaggc tgcaaccgga caggaaaagg acgaagcgga
     5521 tgccggggcc gtccacggtg ccgcaggatt ccacggaatg aaccaaaccg gtgacggagc
     5581 tttctccgtc cggatcatgg ttttgtggaa aaacctgcgg catccgcttg cagtccgggt
     5641 taacgggtgt ggaaagtgcg gttgatgacc tcctgctgct gttcccgggt cagcttgatg
     5701 aaattcacgg catagccgga aacgcggatg gtaagctgcg ggtatttttc cgggtgatcc
     5761 atggcgtcga gaagcgtttt ccgttccagt acgttcacat taatgtggtg acctgtagcg
     5821 gcaaagtagg cgtccagcag ggagacgagc ttgacgcggc gttcacgttc ttccttgccc
     5881 agggcctgag gaacgatgga gaaggtgtag gagatgccgt ccagggagtc gtcataggac
     5941 agcttggcta cggagagcat ggaggccacg gctccgttcc tgtcccttcc gtgcatgggg
     6001 ttggctccgg gggcgaacgg ttccccggct cggcggccgt ccggcgtgtt gcccgtcttt
     6061 ttgccgtaca ccacgttgga ggtgatcgtc aggatggact gggtgggcag ggaattgcgg
     6121 taagtgtgga gcctgcgcag tttttccatg aaattgctga ccaggctgca tgctatgtcg
     6181 tccacgcgcg ggtcattgtt cccgtaacag gggaattccc cttccgtctt gaagtccaca
     6241 atcagccctt cttcattgcg gatggctttt acggtggcat acttgatggc ggacagggag
     6301 tccgccgcca cggaaagccc ggcgattccc gtagccatcg tgcgcagaat ttccggatca
     6361 tgcagcgcca tttcaatgcg ttcatagcag tatttgtcgt gcatgtagtg gatgatgttc
     6421 agcgcgtcaa tgtaagtttt ggcgagccag tcctgcatct tgtcgtacag ggccatcacc
     6481 tcatcatagt tgagaatttc ctccgtgtag cggggggagg gcggggccac ctgcttgccc
     6541 ttgagttcat ccacgccgcc gttcagggcg tagagaaggc acttggcgag gttggcgcgc
     6601 gctccgaaga actgcatctg cttgccgatg cgcatggcgg acacgcagca tgcgatgccg
     6661 tagtcgtcgc cccaatgcgg gcgcatcagg tcgtcgttct cgtattggac ggaggacgtt
     6721 tcaatggaaa ccttggcgca gaagcttttg aaggcttccg gcaggttccg ggaccacaga
     6781 acggtcaggt tcggttccgg agccggcccc aggttgtaca gggtctgcag catgcggaag
     6841 gaactgcggg tgacgagggt gcgcccgtcc tctcccatgc cgccgatgga ttccgtcacc
     6901 caggtggggt ctccggagaa caggttattg taatcaggcg tgcggatgaa acggacgatg
     6961 cgcagcttca tcacgaactg gtcgatgatt tcctgaactt cctcttccgt gatgagcccc
     7021 tgttccaggt cgcgggtgaa ataaatgtcg aagaaagtgg aaacgcggcc cagggacatg
     7081 gccgctccat tctgttcctt cacggcggct aggtagccca ggtacgtcca ttgcacggct
     7141 tcgcgggcgt ttgcggcggg gcgagtgagg tcgcagccgt aggaggcgcc cagctgggcg
     7201 agttcttcca gggcgcgtat ttgttcgctc atttcttcgc gcagacggat cagctcatcc
     7261 gtaagggggg aatgttcacg gtttttgagg tccttgcggc gttcggcaat cagcttatcc
     7321 gtgccgtaca gggccacccg gcggtagtcc ccgatgatgc ggccgcggcc ataggcgtcc
     7381 ggaaggccgg taataatccc ggcggaacgg gccgcccgga tatcggaagt gtaggcgtcg
     7441 aaaacgcctt cattgtgcgt cttgcgtatc tttttgaaaa tgtctgcggt tttctcgcac
     7501 atcttgaacc cgtaggattc cagggcctgt tgggccatgc gcaagccgcc aaagggcatc
     7561 agggcccgtt tcaggggggc gtccgtctgg aggcctacga ccacttccag ttccttgtca
     7621 atgtagccgg gcttgtggga tgtgatggag gataccactt cttcatcagc atccagcacg
     7681 ccgccgttgt ctatttcccg tttcagcagg actttcagct cgtcccataa acgaagcgtg
     7741 cgctgggagg ggccggaaag aaactcttca ttgccggaat agggcgtgta gttatgctgg
     7801 atgaaatccc gtacgtcaat ggactccgtc catgttcccg gcttgaatcc ctgccattcc
     7861 tgcggaaggg cggtggactc cttcaagtct tttactatgc tgatcataaa tagaatgtag
     7921 tgaagaagac tggagaaaaa cgttccgcag cccctgaaag gctggaaacg gcaaaactcc
     7981 gcgccgcgta attatatcgt gaattccggg ggacaacaag gctaattctt tgcgaagaga
     8041 acgcgggtgc gctggctttg gcatgtttca cctgtctgtc cgttgcggag cggaaaatga
     8101 ggggaacatg cgattgcgga aaagtgacgg aagattattt ctctttactt tcctaatctc
     8161 tattgcagta tctcaacgct taccgttatg aaatcttatg catgcctttg tttattgctg
     8221 gcgggagttt tttgcgttgc ttgtttctcc ggtgcctgtg ctgatgaatt gccgcccacg
     8281 ctgaagcccc aggtgaaccc gcgggccgtg tatgactgga aaaaacgtca tgaagcagtg
     8341 atggagcgga accggaccgt caaaccggaa tatgtcgtct ttggtgacag cattacccac
     8401 cgctggggcg gcgagccttc cggggacaac agggctctcg gaacaggaaa aaccgcctgg
     8461 catagcctgt tttcttccca tgcggtaacc aatatggggt ttggttccga ttacgtggat
     8521 aatgcctatt accgcttgca gctgggagag ctggacggca tttctccgcg ggtcatcatc
     8581 gtgctgctgg gaaccaataa tcttggcggg cggaaggatg ctccccgggc ctgcgcagac
     8641 aatctcaagg cttttgtgag cctggcgcgc cggaagtgtc cctcttccaa aatcctgttg
     8701 ctgggcattc tccccaggga gggaaaaaag ctggctcccc tgattaggga aaccaataaa
     8761 atgatatccg gcctggctga cggaaacagc gtgtttttcg ccaatcccgg cgaggaattc
     8821 ctgggggagg acggagtgtc cccaaaaccc gggctgctgg aggatgggct gcatcccagt
     8881 gccagggggt acgacatact ggggaagtcg ttgagcgtat tgctgaagaa aatggacgac
     8941 aagtacggca agctgcccgc tccccggtag atgaatacgg gggagggcgt tcctgttccg
     9001 ggagaggccg ggggatggat gaaatggagc gcgccttgga agaggccgga cacggtgctc
     9061 gcctggccgt ggttgcggca ggatttgccg gacgggcagt ggtctttttt actctgccgg
     9121 aggaagtgac gcctgcgatc ttgatgcacg gcagaatttg cttaaactga aaaccggttt
     9181 tactttttga ttatgaattt cctctcctac atgctcgcca tattgctggg gagttccagt
     9241 ctggcatttt ctgcgccttc cattccggcc tccgcgttgc ccgctaccct gaagccggag
     9301 ccccatcagc gggacccgta tgattggaat gcccggcatg aagccgttaa aaaaagaaac
     9361 cgggccgtca agcctgaata cgtgatgata ggggacagca ttacccacca ttggggaggg
     9421 gagccttccg gggacggaaa aaatacggga tcggggtcct gggagaaatt attcggtccg
     9481 catgcagcga cgaatatggg ctttggattt gattatgtgg ataatgccta ttaccgtgtc
     9541 caaaacgggg agctggacgg catttctccg cgggtcatca ttgtgttgct ggggaccaat
     9601 aatctggggc accgcaagga tacgccgcag gcatgtgcgg acaatatcag ggcatttgtc
     9661 cgcctagtgc gccggaagtg cccctcttcc aaaatcctgt tgctgggcgt tctcccacgg
     9721 aaggagaaaa acctggcgga accggtgaag cagacgaaca gactgttggc ggaactgcat
     9781 aacggaaagg acattttctt tgccgatccg ggaaaggcgc ttctttccgc agatggtgct
     9841 tctccgcaga atgaattcat gaaggatgtg gtgcatccca atgccagggg gtacgaggtt
     9901 ttggaaaagg aactggccgt actcctgaaa aagcttgatg caaaataccg gggagggaag
     9961 caggcgggaa agcattcctg atgatcgtct tctgatggaa ggtaggattt tgcttgaagg
    10021 gaaagccccg gttgaggaaa atatacggcc tttgatattt agtttatgaa aaacctgttg
    10081 tttgcattgt tgaccggttc cttttgttgc tgttatgccc aacagaaggc cgcacccgtt
    10141 ccggaacctg aagttgtcgc cactccgccg gctgatgcgg ggcgcggcct tatccgtgtg
    10201 gactcccgtg aaatacgcca ttattccggt acccgcaagg aaccggatta cctggtcagc
    10261 agggataacg gaaaaacatg ggaaatgaag gccgctccgg ctggctaccc tcccaactac
    10321 ggtggcattc ccaaagaatc tccggctatt gtgcgcaacc ctctgaccag ggaattcatt
    10381 cgtgtgcagc ctatcggggg ctttgtattt ctttccaggg gtgggctgga cggcaagtgg
    10441 cttgccgtca cgaatgacgg caaactggaa gaagactgga aagacccgga aaagaggaaa
    10501 aacctgaaaa aactgggcgg catcatgcgg acccccgttt ttgtgaacaa gggccgcagg
    10561 gtgatcgtgc cgttccacaa catgggcggc ggcaccaagt tccatatttc cgatgacggg
    10621 gggctgacct ggcatgtatc caggaacggt gttacttccc ccagacatga agccaggccc
    10681 ccccaccagg gcgtcagatg gttcaacaat gccgtggaag ccacggtttt ggaaatgaaa
    10741 gacggtacgt tgtgggcgct tgcccgcacc tcccaggacc aggcgtggca ggctttttcc
    10801 aaggattacg gggaaacgtg gagcaaaccg gagccttccc gctttttcgg caccctgacc
    10861 atgaacacgt tgggacgcct ggatgacgga actatcgttt ccctgtggac gaatacaatg
    10921 gctctgcctg aaaatgccac agctggcaac ggaacgtggg aggatgtatt caccaaccgt
    10981 gattcccacc acattgctat gtccggggac gagggcaaaa cctggtacgg gttccgggag
    11041 attatcctgg acgaacaccg caaccatccc ggctatgcta cgctggatgg tccggaagac
    11101 cgcggcaaac accagagcga aatggtgcag ctggacaaaa accgcatcct tatttccctg
    11161 gggcagcata aaaaccaccg ccgcctggtt attgtggacc gccgctgggt aggggccaag
    11221 acgcgtgcca cgcagacggg gaaagatttg gattcccagt ggaccattca cacttatatc
    11281 ccccagaaaa aaggccattg cagttataac cgcaagcctt ccgccgagct ggttcaggat
    11341 ccgtccgggg gcacgaagaa ggtgttgcaa atcaagcgtc tggatgatcc cgaactggtc
    11401 aatgaaaaat ccaatgtgga ttaccggaac ggcggagcta cctggaactt tccgaacggg
    11461 accacggggt tggtcaaatt ccgcttccgt gtagcggacg gggagcaggc ggatgattcc
    11521 ggccttcagg tctctctgac ggaccggctg ttcaatgcct gtgattccac tacgaaggat
    11581 tatgccctgt ttaccttccc gatcaggctg agacctgcgc cccatctgtt gctggggatg
    11641 aaaaaagtgc ctttctcgcc cggcgcgtgg catgaaattt cccttctttg gcagggtggg
    11701 caggccgtgg tgtctctgga cggaaagaag gccggaacgt tgaaaatggc taataagtcc
    11761 cctaatggag tcagttatat ccatttcatc agcaccgggt cccaaccgga tgccggcatt
    11821 ctgctggata cggtgaatgc ccgggtgaag taaggatcgg cgggattcaa tggttttcct
    11881 tcttcggaag cggcggagcg cttaattccg gcaggtattt cagcaccatc tggagatgtt
    11941 cgtttgaccg gttgcctatc ctctggaggg ctgtgcgtcc gtatttgtct ttcagggatg
    12001 ggtttgcgtg gtggtccagc agaagacgcg caatacccag tttcagccgg tccagggaat
    12061 cgtctcccag cagcatgcct cggcagcatg ccatgagggg agtttctccg gcggcgtttt
    12121 gatggttgac gtcagctccc tctttgatga agagattgac cagatccctg atttgaggga
    12181 ggcaggacac atcaatgaaa gccagctggc ggcacaggtt tagcagggcc gtgtctcccg
    12241 ctgtttccgg cagggtggtg gacgcgggca tggccgcatt cacgtccgct ccgtattcca
    12301 gcagaatatg tgcaatttgc agtgcggcgt tcggagtgtt caggttcagg gaaagaaggg
    12361 gcggggccat ttccccgcgg aaattgggat cgtacccggc ttcgcaaagc ttgcggacca
    12421 gcagggggta tccggcggcc gcggcccatg tgagcagact tgttttttta cctttcaatt
    12481 caggctggag ggaaatatcc gcaccgcatt tcagaagaaa cagggccgct tcctcatagg
    12541 gtgctcctcc aataccggct acacaggtga tgatgagggg cggccagccc agcggccccg
    12601 gtttattcac atccgcaccg tactgaatca ggagattaag gcaggagagc ctgttatgca
    12661 ccggcagggg cgtggagtcg tccatgcctg gctggcaggc gtaagtcagg ggggtatttc
    12721 cctgttcgga gtccggaatg gagggaaagg cctgttgcgg caggatgatc tggacgttcg
    12781 ggtccgcatg gcgctgtaaa aggcggttca gcaactgcac ttctccgagc ccggcggcga
    12841 gatgcagcag ggtttcatgg gatggagtga tgcagcgtcc gtctgcgctt tccgccgtgt
    12901 cccgtatcat ctgaagccgt tccctgattt cgtccttcat atattggcgc atggaaacct
    12961 cggaaaacat gtgccagtca atatggcgtg aattgaggga aagcccgcgg taaatgaaac
    13021 gttccgggct tcgatgggct gtgaaattcg ctgcggtaag aatttgttct ttttccgctt
    13081 ttgtccagat agggttgaaa ttccattctg cgggagaaga atcattcctg ttcagccaga
    13141 aaacagcgaa agccgcggca agagaggcaa aaaagctcaa agctccaaga aaccagagag
    13201 ttttctttct taaagtcatg tgtatcataa gcaggggtac tgcgaaaggc catgatgcag
    13261 gaatccataa ctccgggcaa tgaaaaaata gtatgagcaa agaatgcccg gggcaaacca
    13321 tgtgggaatt cgggtggcgg attgcaaatt cggaggagaa tttttttcct cttcatctgg
    13381 gaaaaaagct cgtggataaa gagaattacg aaggaaacgg aaaatatggt gtcatgggcc
    13441 ggacttcaca aaaattatgg agtttatggc gtggatcatt taactccaat tatttgaatt
    13501 gtatccgaat ttgcaattcg gtgtgatacg ctaaatattg cggatgtgcg gatggtttca
    13561 aattatttgc atttgccgct gctgcactca cggtagaatg aaggaagctg aaacttatgg
    13621 aagaaatgga gattctcccg taaaatgatg gagagaactg tatccttgct gctggcctcc
    13681 tggtctttcc tttcgctgtc cgctccatgc tgtctgaagc cgctcttgcc ctggaagtaa
    13741 ggataaacga tgattctggc agcgttatgg attccgtcaa acttattgcg tccgatatgg
    13801 atgggacgct gcttaatgga aaaggtgaat tggaccctgc gttttttccc ttgtttaggg
    13861 aacttgagct tcgcggcatt cgttttgcgg cagcaagcgg ccgccagtat gacggattgc
    13921 tccggacctt tgcccccgtg gcggaccgga tgctgtttat tgccgagaat ggcgcttatg
    13981 cggcggcggg tagaaaagaa tggctgcttc tggacatgga tcatgaaacg gtagccggtt
    14041 tgattgccgg gatcaggcgc attgaaggaa cctgcatcgt cctcgcaggg cgggattccg
    14101 catatattga ggacaaacag ccggaattcg tccgggaggc ccgcaaatat tacacacgct
    14161 gtcaagaagt gggggacctg ctggacgtgc ggggggacaa acttttgaaa atagcagtat
    14221 atgacttcct gggagccggg gaaaacagtt ttccccggct gaagcatttg gaacatggct
    14281 tccaggtggc tgtctccgga gagaaatgga tggatatcag ccggaaaggg gccaataagg
    14341 gggccgccct ggaattgatt cagcggaaac tgggagtttc tccggaggag acgatggttt
    14401 tcggggatca gatgaatgac gctccaatga tgcggcaggc gcgtttcagt tatgccatgg
    14461 cgaatgccgt gccggaaatc cgttccatgg ccgcatttga ggcgccgtcc aatgaggaaa
    14521 acggagtgat gcaggtgctt ggaaagatgt tggacgccca ttctccgcag ggaaggtccg
    14581 ggaattgcag gaaaccccgt ttctaattgc cgggtaatgg aataaaatca gggttatgtt
    14641 gatgttattg tcagattttt ttaatatgct ggcgatggcc gtgttcgctt gcattggcgg
    14701 tgtttttctg ggaatgggct ttctgctgct taaattggcg ggaatttttt tcggaatatt
    14761 ggcggggtgt attattctga tggaagcggc cggaaggtgg atttcccatt tgatgggggc
    14821 gtgagtccgt tattcccggc aatgaagggg attcctgtac gctttccgtg aggggagggc
    14881 tttctgatgg ctgggtcatt gccggctgct gttgttgccg gttcattgcc gaatgctgaa
    14941 gtggaaggct gcatcctgcc tggattctgc gtgttaaaac cggatagcgg agttttgtga
    15001 taaacagacg tttgccgtaa gatgccctgg aagacagagc cccgcagaaa ggaagtccca
    15061 gggatatgaa atgccgggcg tccccatgga agggactgtt gtctttgtac tatttgacag
    15121 ggcgggagac ggaattttac cgtccctccc gtcagcatga aagctgttgt cctttttagt
    15181 tttgcttttc cgcaatgtct gtggtacacc cgtgccagac gtcatgaatc aggaattttt
    15241 ttcagtgctc gtgcaggtgg cggccgccct ggggctggcc ggcatgatct tgttgctcag
    15301 tatcttgatg ggca
//
