LOCUS       c00136_gnlPro..        14139 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AOLIJMIF_136.
ACCESSION   c00136_gnlPro..
VERSION     c00136_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 09:48:14
            Original ID  :: gnl|Prokka|AOLIJMIF_136
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14139
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14139
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[9939:13497](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      9940..13497
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..14139
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14139
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             2..1168
                     /locus_tag="ctg136_1"
                     /transl_table=11
                     /translation="LHFADTLGNCPVWYSDFWMNHPQYWTNDPSQGWNSAGALDFSHKE
                     VREHKLAIIAEQLEKYEMIDGFDLDFMRFIVNFKTEEYAQNVEVMTQFVRDIRSKVDQI
                     SVKRGRKILLSARVPPTVRDCLDKALDVKTWIREGLVDFLSIGVHWRGNPAMPVARFKE
                     DLNGLKIPVYASIDDGGYKARELWSHGMHRGMASHALAQGADGLYLFNFYFGQYANAGK
                     KYTLEPGSLVCRAMIPELLQELGSLNTLKNRNKIYALSDGIREYRVDPGSPLPLNVVGN
                     AVAPFFIGDDVKKHPPLEAILFIRNNENTDFKVFVNDILLVEQRSEYVALYDKARGLKG
                     KECEYAFIVPVNEMIKGYNNIRFEGEGFVVKRIELALKYGEVETHGYF"
     CDS             1137..3674
                     /locus_tag="ctg136_2"
                     /transl_table=11
                     /translation="MGRWKRMGIFDKKRIIVVCFFVFFCQMIFSQSQKFRGYPQKDADI
                     LSGFSCPPKGYGNVPFYWWNGDSLNRERMKEQLEILSESATDGFAVSYIHLDPKVDVEN
                     MKDGYGLFGKTESGRPKIFSEDWWNTWSWFAKECASKNIGLGLDDYTVGWIGNGYYSDE
                     LQEMAKFRGYQGELNIQSVTVKGGTTFTYDIPDKFLTAVVWPGKTDLTKYISGDKLLWE
                     VPCDNSYKVYIISTKENHLLHPDIGKEYVRVYFDRFERRMSDAVPDGMNYFFQDELSYP
                     IKMGSWAEDFRDEFEKRKGYDITLYLPALKEFIGDITPKIRLDYCDVLMDLAEERYFRP
                     IYDWHVSRGLIYGSDNLRRGKDPLAYVDYFRANSWYTAPGNDAPSTGSSFLQTKVSSSI
                     THLYERQRTWLEAFHSMGWGSSASWLTKQMDHHFMAGGNLVCMHGLYYSTHGGWWEWAP
                     PCFHFRMPYWPHMKRWLEYTERLSYLMSQGTHVCDIALMYPTESLQAYPEANTKITFDQ
                     AMKLSNAGLDYDFMDYRSLQKAKVADGCLHVAGEKYKILILANMKALHYASMEKVLEFY
                     RAGGIVIATGELPKASTRIGENDPVVDAMVREIFGLTAGEVVRGKTTDKRVNTSGGTGI
                     YIAGDDLVEQIWSQITPDFKPVGGAGKALHRCIGERNVYMVMDVPKGTECFFRATGKVE
                     LWNASDGTIIDYPVVRQTEEGTWLLLEKESDNSYLFVFSPGIPVFLPEYRKESIQIYHT
                     AITGVWETELLPTMDNKWGDYRFPASDMIGAEARSFKHCAAALSPDNWMNPYFDDSGWK
                     ESIYGYGEQFVSYFKSAGESMSNISXXXXXCFG"
     CDS             3823..4815
                     /locus_tag="ctg136_3"
                     /transl_table=11
                     /translation="MVYAPAKDNYRVEVCGIKPDFLLVDGKAVNENLLLDQGWHQVVVA
                     YIGTPKTEFKFQKGAYRDFRERSAVVFFPASSLTPEKPSTYAKVISTRWALGDHLLYDP
                     YGGDNLMWNYRFRSAPGTEELEITVVGQDLKIWHNGKEITGKNVQLLSTDRSGICKYRV
                     IIPTPRKDAGLIAFSVRRKPGYQGTAVICEPIKIKTGKGILEAGNWSETGALKHYSGGM
                     YYRKEVVIPSIKSNNKVILDLGEVNASCEVKVNGQDVGIVMGSLYTVDISKQVKSGKNH
                     IEVLVYSTLSNHYQIIPTPYRGDGVAGLLGPVSLTVWETPSLKTKVPVR"
     CDS             complement(4942..5046)
                     /locus_tag="ctg136_4"
                     /transl_table=11
                     /translation="MKYILFITMDLAVYPFLLLFYIVKCIFDKIQPAH"
     CDS             5399..6265
                     /locus_tag="ctg136_5"
                     /transl_table=11
                     /translation="VLVLAASPSFVSCGGQRPVRFGVVTDLHYSRWEPYGTRYFPQTMD
                     KLKEAMEVFNSSNLDFVIEMGDLKDQDNVPRREQTITYLDEIENVFQSFRGPVYHVLGN
                     HDMDSISKDDFLQHTSNQGDADKKAYYSFAFDNIKFIVLDANYNLDGTPYDKGNFDWTK
                     AYIPEDQIGWLRKELKGNNKPVIIFIHQLLDRFSDISKSLCVSNADEIVPLLEENGNVL
                     AVFQGHHHAGHYSFRNNIHYWTMKGMIEGNLPDNNSFAVVEIDTQNNIHIDGFYNCEDK
                     DLNRFTV"
     CDS             complement(6488..7438)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MTHFR"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg136_6"
                     /sec_met_domain="MTHFR (E-value: 2.2e-64, bitscore: 206.9,
                     seeds: 12, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVIDLINGSKTTAFSFEILPPLKGNSIQKVYNVIDKLKEFDPKY
                     INITSHHSEYIYKTLPDGSFQKVNIRKRPGSVAIASAIQNKYGIPAVPHIICKGFTKDE
                     TEYALIDLNFLGVYDLLLLRGDVKTLEAGQNTDLYHEHATDLQEQVNNFNKGIAVDGST
                     FEANETPFSYGMACYPEKHEEAPNMESDIFYLKEKVKNGADYLVTQMFFDNEKYYSFVE
                     RCRAEGIDVPIIPGIKPVVFKNQLTVLPKIFRSDIPEPFATELRKCKNDDEVKAVGVEW
                     CIQQCKDLIAHGVPSLHFYTMMATDSVYKVAKEVY"
     CDS             7522..8541
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_4"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg136_7"
                     /sec_met_domain="Aminotran_4 (E-value: 7e-32, bitscore:
                     100.4, seeds: 70, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENMNWSDLAFGYMKTDYNVRCYYRDGKWGELEVSSSEIINIHMA
                     ATCLHYGQESFEGLKAFKGKDGKIRVFRMDENGKRMQASSRGIKMAELPVEMFEEAVRK
                     VVKLNERFVPPYESGAALYIRPLMIGLGAQVGVKPAPEYMFMVFVTPVGPYFKGGFQPS
                     KVCIMREFDRAAPYGTGTIKVGGNYAASLVAGEIAHSKGYAAVLYLDPKEKKYLDECGP
                     ANFFGIRGNSYITPQSHSILPSITNKSLQQLAEDMGLTVERRPVPFEEIATFDEAAECG
                     TAAVIAPISQIDDLDENKSYVIAKDGKPGPVCEKLYHKLRGIQYGDEPDTYGWVTIIE"
     CDS             8729..9907
                     /locus_tag="ctg136_8"
                     /transl_table=11
                     /translation="VEAFFKTHKYLVEHLHAPVRRGLMDEIDWNDRLIGIKGSRGVGKT
                     TFLLDYAREHFGADNKECLYINLNHFYFTERTLVDFASEFRAKGGKVLLIDQVFKYSGW
                     SKELRYCYDNFEDLKIIFSGSSVMRLKEENPDLSGKVVSYNLRGFSFREFLNLMSGNSF
                     PAYTFEEIIGNHQEIAKNICSVAKPMAYFQDYLHHGFYPFFLEKRNFSENLLKTMNMML
                     EVDVLYIKQIEQSYLPKLRKLLYLLAISAPCTPNVSQLSKEIETSRATVMNYIKYLTDA
                     RLMNMLYPVGESFPKKPSTVYMYNSNLMYPIRPMEVNVQAVRESFFYNQLLKDNTLNEG
                     MKNAHFLVNGKYNFRIEENMKVKNNPDLYYAVDKVEVGEENMIPLWLFGFLY"
     CDS             9940..13497
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg136_9"
                     /sec_met_domain="PFOR_II (E-value: 6.6e-20, bitscore: 60.9,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 3.5e-83, bitscore: 268.2,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 3e-32, bitscore: 101.5,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3e-13, bitscore:
                     39.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 3.5e-13, bitscore: 39.8,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 5.9e-08, bitscore: 21.9,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.6e-05, bitscore: 14.9,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 6.9e-25, bitscore: 76.2,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFLTCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTSTYTASQGLLLMIPNMYKIAG
                     ELLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFVNFFDGFRTSHEIQKIEALENDDLAPLIDQKALAEFRARALNPEKPEARGMAE
                     NPDHFFQHRESSNKYYEAVPAIVEEYMNEISKLTGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLTAQGEKVGLVSVHLYRPFSAKHFLAAVPKTAKRIAVLDRTKEPGATGE
                     PLYLDVKDCFYGQADAPVIVGGRYGLGSKDTTPAQIIAVYENLALPMPKNQFTLGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTNKYCQAYFSYDS
                     KKSGGFTCSHLRFGDHPIRSTYLVNTPNFVACHVQAYLRMYDVTRGLRENGTFLLNTVW
                     NGEELAKHLPNKVKRYFAQKNITVYYINATQIALEIGLGNRTNTILQSAFFRITGVIPV
                     DLAIEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYTQLTVDPDWANLPDDEVVANNDP
                     AFINEVVRPINAQDGDLLKVSAFEGIEDGTWHQGTAKYEKRGVAAFVPVWEPDNCIQCN
                     KCAYVCPHASIRPFVLDAAEQAAAPFNNSLKATGKQFEGMQFRIQVDVLDCLGCGNCAD
                     VCPGNPKKGGKALKMAALETQLDEAPNWDFCAEKVTTKQHLVDIKANVKNSQFATPLFE
                     FSGACSGCGETPYVKLVTQLFGDREMVANATGCSSIYSGSVPSTPYTTNDKGQGPAWAN
                     SLFEDFCEFGLGMELANEKMRARLTNAMNEIIAADNAPAEAKEVLKAWVENQNDADKTK
                     ELAPQVLAIAEEGITHGCPLSAQIKELSHFLVKRSQWIIGGDGASYDIGYGGLDHVIAS
                     GKNVNILVLDTEVYSNTGGQSSKATPVGAIAKFAASGKRIRKKDLGLMATTYGYVYVAQ
                     IAMGADQAQTLKAIREAEAYDGPSLIIAYAPCINHGLKKGMGKSQQEEADAVACGYWHL
                     WRYNPALEEEGKNPFSLDSKEPDWSKFQDFLKGEVRFASLTKQFPAEAAQLFQAAEDNA
                     KWRLNNYKRLAKQQWGVEE"
     CDS             13607..14137
                     /locus_tag="ctg136_10"
                     /transl_table=11
                     /translation="MAKNKSKQNQFQLLSPEKYIRLKARNLPIEVCYVSDDWKDERGAV
                     AEVIVVRRHAGGNYTFGVYVVDTLCLGVKHSVYRFNVPPDEYDDFVERTATDCGIKISY
                     NEAHNFIYGAIAFAEEFGIKPDKSFALTQYILEEDTEEIPLIEYKYGRGGRPHLVVETS
                     LEASKYIPILEEST"
ORIGIN
        1 cctacatttt gcagatactt tgggaaattg tcctgtatgg tatagtgatt tttggatgaa
       61 ccatccgcaa tattggacta acgatccttc acaaggatgg aatagtgccg gtgcactcga
      121 cttttcgcat aaggaagtgc gggaacataa actggctatc atcgccgagc aactggaaaa
      181 atatgagatg atagacggtt ttgatctgga ttttatgcgt tttattgtaa atttcaaaac
      241 ggaggaatat gcacaaaatg tggaagttat gacacaattc gtaagggata tacgaagcaa
      301 agtagatcaa atttcagtaa agcgtggaag aaaaatatta ttatcggcac gtgtcccgcc
      361 tactgttcgg gattgtttgg ataaagcttt ggacgtaaaa acatggatac gggaaggact
      421 ggttgatttt ttaagtatag gagtgcattg gcgcggaaat ccagctatgc cggtggctcg
      481 ttttaaagag gatttaaatg gtttgaaaat tcccgtttat gcaagtattg atgatggtgg
      541 ttataaggcc cgtgaattat ggtcacatgg tatgcatagg gggatggcgt cacatgcttt
      601 ggctcaggga gccgatgggt tatatttgtt taatttctat tttggtcaat atgctaatgc
      661 cggaaaaaaa tataccttgg agcctggtag tttggtatgc agggcgatga ttcctgaatt
      721 gttgcaggaa ctcggctcgt tgaatacatt aaaaaacagg aataaaatat atgctttatc
      781 agatggcata agggaatacc gtgttgatcc gggttctcct ttgccattga atgtagtagg
      841 aaatgctgta gctccatttt ttatagggga tgatgtaaaa aaacatccgc cattggaggc
      901 tattcttttc atccgtaata atgagaatac ggattttaag gtatttgtca atgatatcct
      961 tttagtagaa cagcgttcgg aatatgttgc tttatacgat aaagcacgcg gactgaaagg
     1021 taaagagtgt gaatatgcct ttattgttcc ggtaaatgaa atgattaaag gatataataa
     1081 cattcgtttt gaaggtgagg gttttgttgt aaaaaggatt gaattggcac taaaatatgg
     1141 ggaggtggaa acgcatgggt atttttgata agaaaaggat aatagtagtt tgtttctttg
     1201 tttttttctg tcagatgatt ttttcccaat ctcagaagtt tagaggatat ccgcaaaagg
     1261 atgcagatat tctttccgga ttttcctgcc ctccgaaagg ttatggaaat gttccctttt
     1321 attggtggaa tggtgatagt ctgaacagag aacggatgaa agaacaactt gagattttgt
     1381 cagagtcggc aacggatggt tttgctgtga gttatattca tttggatcct aaggtagatg
     1441 ttgaaaatat gaaagacggg tatggcttgt ttggaaaaac agaatcagga aggccaaaaa
     1501 tcttttcaga agactggtgg aatacctgga gttggtttgc aaaagaatgt gcatcgaaaa
     1561 atatcggatt aggattggat gattatacgg ttggttggat cggtaatggg tattattctg
     1621 atgagttaca ggaaatggca aaatttcgtg gttatcaggg ggaactgaat attcaatcgg
     1681 taactgtaaa gggaggaaca acttttactt atgatattcc tgataaattc ttgacagcag
     1741 tagtatggcc gggaaagaca gatttaacaa aatatatctc cggagacaaa cttttatggg
     1801 aagtaccgtg tgataacagt tataaagttt atatcatatc gacaaaagaa aatcaccttc
     1861 tgcatccaga tataggtaaa gagtatgttc gtgtatattt cgatcgtttc gaaagacgta
     1921 tgagtgacgc tgttcctgac ggaatgaatt atttttttca ggacgaattg tcatatccta
     1981 ttaaaatggg atcatgggca gaagattttc gggatgaatt tgaaaaaagg aaagggtatg
     2041 atataacttt atatctgccg gcattgaaag agtttatagg tgatatcact cctaaaatac
     2101 gtttggatta ttgtgatgtc ttgatggatt tggcggaaga acgttatttt cgtcctattt
     2161 atgattggca tgtttcgcgt ggattgatct atggtagtga taatctgcgc cgtggcaagg
     2221 atcctttagc atatgtggat tattttaggg caaattcctg gtatacagct cccggtaatg
     2281 atgctccatc aacaggctcc agttttctgc aaactaaggt gtcgagttct attactcatc
     2341 tgtatgaacg tcaacggaca tggttggaag cttttcatag catgggatgg ggaagttctg
     2401 cttcatggtt gactaagcag atggatcacc attttatggc tggtgggaat ttggtatgta
     2461 tgcatggatt atattattct acccatggag gttggtggga atgggcacct ccttgtttcc
     2521 attttagaat gccctattgg ccgcatatga aaagatggct tgaatacacc gaaaggctga
     2581 gttatttgat gagtcaggga acacatgttt gtgacatagc actgatgtat ccgacagaat
     2641 ctttgcaagc atatcctgaa gctaatacta aaattacttt cgatcaggct atgaagttga
     2701 gtaatgccgg tttggattat gactttatgg attatcggtc attacagaag gcaaaagtgg
     2761 cagatggctg tttacatgtg gcaggtgaga aatataaaat actcatactt gctaatatga
     2821 aagcattaca ttatgcatct atggaaaaag tgttggaatt ttaccgggca ggtgggattg
     2881 tcatagcaac aggggagttg ccaaaggcta gtacgcgcat cggggaaaac gatcctgttg
     2941 tggatgcgat ggttcgtgaa atatttggct tgactgcagg tgaagttgtt cggggcaaaa
     3001 caacggacaa gcgggttaat acatctggtg gaactggaat atatatagca ggcgatgatc
     3061 tggtggaaca gatctggtca cagattaccc cggacttcaa acctgttggt ggagctggaa
     3121 aggctttgca tcggtgtatc ggggaaagga atgtatatat ggtcatggat gttcccaaag
     3181 gtacggaatg ttttttcaga gctactggca aagtggaatt gtggaatgca tctgatggga
     3241 caattataga ttatcctgtt gtccgtcaga cagaagaggg aacatggctt ttgcttgaaa
     3301 aagaatcgga caactcgtat ttgttcgttt tttcaccggg aataccggtg tttttaccgg
     3361 aatatcggaa agaatcgata cagatttacc atactgctat tactggggta tgggaaacag
     3421 aattattgcc aacaatggat aataaatggg gggattatcg ttttcccgca tcggatatga
     3481 taggtgctga ggctcgttcg ttcaagcatt gtgcggctgc actatcacct gataattgga
     3541 tgaatcctta ttttgatgat tctggttgga aagaaagtat atatggttat ggggaacaat
     3601 ttgtaagtta tttcaaatcg gcaggggagt ctatgagcaa tatatctgnn nnnnnnnnnn
     3661 natgttttgg ctgaaagtag gaagccggga aaaatattgg aattttcatg gcagttcgga
     3721 gtctttgaca accccggttc acagggatgg catggactaa aaggaaaagt aagcgacggt
     3781 ttctttatct tggatcaggg gggccaccaa atataccgta gtatggttta tgcacccgca
     3841 aaggataatt accgagtgga agtgtgtggt attaaacctg attttctatt ggttgatggg
     3901 aaagctgtta atgaaaatct tttactagat caaggttggc atcaggtggt tgtcgcctat
     3961 atcggtaccc ccaaaacgga atttaaattc cagaaaggtg cttataggga ttttcgagag
     4021 agaagtgctg tagtgttctt ccctgcatct tctcttacac cagagaaacc gtctacttat
     4081 gccaaagtca tttctacgcg ttgggctttg ggagatcatc ttttgtatga tccttatgga
     4141 ggtgataacc ttatgtggaa ttaccgtttt cgttctgcgc caggtacgga ggaattagag
     4201 ataactgtag tagggcagga cctgaaaata tggcacaacg ggaaggaaat aacaggaaaa
     4261 aatgttcagc ttctttcaac ggatcgctcg ggtatatgca agtaccgggt tattattccc
     4321 actcctcgga aggatgcagg attaattgct ttctcggtta ggcggaaacc tggttaccaa
     4381 ggaacagctg tcatttgcga accgataaag ataaagactg gcaaaggtat actggaagct
     4441 ggtaactggt cggaaacagg ggctcttaag cattattcgg gggggatgta ttataggaaa
     4501 gaggttgtta taccctcaat aaaatcgaat aataaggtaa ttcttgattt gggcgaagtt
     4561 aatgcgtcgt gtgaggtaaa agtcaatgga caagacgtag gtatagttat gggttctctg
     4621 tacacggttg atatcagcaa acaggtcaaa tcagggaaga accatataga agttctggta
     4681 tacagcacat tgtctaatca ttatcaaatt atccctactc cctatagagg tgacggtgtg
     4741 gcaggtttgt taggtccggt gtcgctgacg gtttgggaaa ctccatcgct taagacaaaa
     4801 gtccctgtaa gataatgttt ccagcgaaga cacattataa gaagcaatta aaaaggcctt
     4861 nnnnnnnnnn attataccga atgaattttg tcaggatggt cattcggtat aatttgtttt
     4921 taagttcttt tgtattgaaa atcagtgagc tggttgtatc ttatcaaaga tgcattttac
     4981 tatataaaat agtagcagaa aaggatatac tgccagatcc atagtaatga atagtatgta
     5041 tttcatttct tttttctttt aaattccacc tgtaagacag aaatatttca aaaaccccta
     5101 tcggcctgac agattttttt gtatttgtat gaaaagaaga tgagtaaagg cattaaaaag
     5161 atgcatctgg gtttgaaatt ggtgtaattt aacaaataag cttttttcgg gagattgaaa
     5221 atttgttctc aactcatcca aaatccggga tggtagatat attgactttt tattattaat
     5281 attgtaagcc aatgctgata gcctgctaca tccggcaggt taccggcatg actctataac
     5341 ctatgaaatt tttaagatga tgaacagacg cttattttta aaaaaggcat gcggaggggt
     5401 gttggtcctg gcagcttctc cttcatttgt atcttgtggc ggacaacggc ctgtccggtt
     5461 tggggttgtt accgatctgc attattcgcg gtgggaacct tatgggaccc gttatttccc
     5521 tcagacaatg gataagttga aagaggccat ggaggtcttc aactcttcca atctggattt
     5581 tgtgatcgaa atgggcgatc tgaaagatca ggataatgtc ccccggcggg aacagacaat
     5641 tacttatctg gatgaaatag aaaacgtctt tcaatcgttc cggggaccgg tttatcatgt
     5701 cctgggaaat catgatatgg atagcatctc caaagacgat ttcctgcaac atacctccaa
     5761 tcagggggat gccgacaaga aagcttatta ttcatttgcc tttgataata taaaattcat
     5821 agtcctggat gcgaattaca atttggacgg tacaccgtat gataaaggta attttgactg
     5881 gacaaaggct tatatccctg aagaccagat aggctggctg agaaaagaat tgaaaggaaa
     5941 taacaaaccg gtcatcattt ttatccatca gttgttagac cgcttctccg atatcagtaa
     6001 atcgctttgt gtaagtaatg cggacgaaat agttcctctg ttggaagaaa atgggaatgt
     6061 gctagctgta ttccagggac atcatcatgc gggacattac agtttccgta ataatatcca
     6121 ctactggaca atgaaaggga tgatagaagg aaaccttccc gataacaaca gttttgctgt
     6181 tgtggagatc gatacgcaga ataatattca tatcgatggt ttctataatt gtgaagataa
     6241 ggatttgaat cgcttcacgg tgtaaagtta ttcagttgat ctgcgtaaag caatctaatg
     6301 ttttttcaga cagaggtagg tctaaataaa tttagaggta ggtgtaaatc gaattagagg
     6361 tacgtctaaa ttcatttaca cctacctcta atttataaga catagtaatg ttctccggat
     6421 ttagtcagta ttatgctttt tatccaaccc gttgtctcct ggcaatcgat tagttctacc
     6481 aacggtttta atatacttct tttgccactt tataaacact atccgtagcc atcattgtat
     6541 aaaaatgcag gctggggaca ccgtgggcga tcaggtcttt gcattgctgg atgcaccatt
     6601 cgacaccaac ggcttttact tcatcatcat ttttacattt ccgcaattcg gtagcaaacg
     6661 gttcgggaat gtctgaacgg aatattttag gtaatacggt cagctggttt ttaaagacaa
     6721 ccggcttgat gcctgggatg atcgggacat cgataccttc ggcacggcag cgttccacaa
     6781 atgaataata tttttcatta tcgaaaaaca tttgggtaac cagatagtcg gcaccgtttt
     6841 ttactttctc tttcagataa aaaatatccg attccatatt cggtgcttcc tcatgttttt
     6901 ccggatagca agccataccg tatgagaacg gtgtttcgtt tgcttcgaat gtggaaccgt
     6961 ctacggcaat acctttattg aaattgttta cctgttcctg aaggtcagtc gcatgttcgt
     7021 gatataaatc cgtattttgt ccggcttcca gtgtttttac atcaccacgc aacagcagca
     7081 ggtcgtaaac tcccaggaaa ttaagatcga tcaatgcata ttccgtttca tcttttgtaa
     7141 atcccttaca tataatatgt ggaactgccg gaataccata tttgttctgg atggcagaag
     7201 caatggcaac cgaacccgga cgcttgcgga tgttcacttt ttggaagctg ccgtcgggca
     7261 aggtcttata gatatattcg ctgtggtgag aagttatatt aatgtattta gggtcgaatt
     7321 ctttcagttt atcaatcaca ttatatacct tctgtatgct gttccctttc agaggaggta
     7381 gaatttcaaa tgaaaaagca gtcgttttac tgccgttgat cagatcaata actttcatat
     7441 tttaattatt tttgctgcaa aagtaacaat tatcatccga aatagcttac ttttgcgctc
     7501 ataatctaat tacgacaaga tatggaaaat atgaattggt ctgatctggc attcggttat
     7561 atgaagacag actacaatgt acggtgttac tatcgtgatg gtaagtgggg tgaattggaa
     7621 gttagctctt ctgaaattat taatattcac atggcagcta cttgcctcca ttacggacag
     7681 gagtcgtttg aaggtttgaa agcattcaag ggaaaagacg gtaaaatccg tgtgttccgt
     7741 atggatgaaa acggcaaacg tatgcaagct tccagccgtg gtatcaagat ggctgaactt
     7801 cctgtggaaa tgtttgaaga agcagtccgt aaagttgtga aattgaatga acgctttgtt
     7861 ccgccttatg agagcggggc agcattatat attcgcccgc tgatgatcgg cctgggtgca
     7921 caggttggtg tgaagccggc tcccgaatat atgtttatgg tgtttgtaac tccggtagga
     7981 ccttacttca aaggtggatt ccaaccttca aaggtttgta tcatgcgtga gttcgaccgt
     8041 gcagcacctt atggaacagg tacgatcaaa gttggtggta actatgcagc cagtttggtt
     8101 gccggtgaga tcgctcattc aaaagggtat gcagccgtgt tgtatctgga cccgaaagaa
     8161 aagaaatacc tggacgaatg tggtccggct aacttcttcg gtattcgtgg aaacagctat
     8221 atcactccgc aatctcattc catcctgcct tctattacaa acaagagttt gcagcaattg
     8281 gcggaagata tgggactgac ggttgaacgt cgtcctgttc cttttgaaga aatagctaca
     8341 ttcgatgagg cggcagaatg cggaacagca gccgtaatcg ccccgatttc acagattgat
     8401 gatttggatg aaaataaatc atacgtgatt gccaaagacg gcaaacccgg acctgtttgt
     8461 gaaaaactat atcacaaact gcgtggcatc caatacggtg acgaacctga tacatacggt
     8521 tgggtaacga taattgaata atcagataaa agatgttgac agttaatgct tttggataaa
     8581 tcgggagtgt taactgccaa ctctaaattc tcaaacgtca atacgctttg ccaactttgg
     8641 attgccaact gaaaataaaa ttgctatctc ggtgttgcaa agttgaggat attttctatc
     8701 tttgcggtct atatagtaag acagtcaggt ggaagcattc tttaaaacac ataaatacct
     8761 tgtagaacat ttgcatgcac cggtacgccg ggggctgatg gatgagattg attggaatga
     8821 ccggttgatc gggatcaaag gctctcgtgg agtagggaaa actacttttt tgctggatta
     8881 tgcccgcgaa cattttggtg ctgataataa agagtgcctg tatataaatc tgaatcactt
     8941 ttattttacg gaacgtacgc tggtcgactt tgcttctgag ttcagggcaa aaggagggaa
     9001 ggtgttgttg atcgaccagg ttttcaaata ttccggatgg tcgaaagagt tacgttattg
     9061 ttatgataat tttgaagatc tgaagattat cttttccggt tcgtcagtga tgaggttgaa
     9121 agaggaaaat ccggatctct caggtaaagt tgtttcatat aatttgcgtg gtttttcttt
     9181 ccgagagttt ttgaatctga tgtcgggaaa cagttttccg gcttatacgt ttgaagaaat
     9241 aatcgggaac catcaggaga ttgcgaagaa tatttgttcg gtagccaaac cgatggctta
     9301 ttttcaggat tatttgcatc atggttttta tccgttcttc ctggagaaac gcaatttctc
     9361 agagaacctg ctgaagacaa tgaatatgat gctggaggta gatgtcttgt acatcaagca
     9421 aatcgagcaa agctatctgc ccaaactccg caaactgttg tatctgctgg ctatcagcgc
     9481 accgtgtacg ccgaatgtta gccagttgag caaagaaata gaaacgtcac gggctacagt
     9541 gatgaattat ataaaatatc tgaccgatgc ccgtttaatg aatatgttat atccggtagg
     9601 cgagtcgttt ccgaaaaaac catctaccgt gtatatgtac aattcgaatc tgatgtaccc
     9661 catccgtccg atggaggtaa atgtgcaggc tgtgcgcgaa tcttttttct ataaccagct
     9721 tttgaaagac aatacgctaa atgagggaat gaagaacgca cactttttgg taaacggaaa
     9781 gtataatttc aggatagagg aaaatatgaa agtaaaaaac aatcccgatt tatactatgc
     9841 tgtagacaag gtcgaagtag gagaagagaa tatgatcccg ctttggctgt ttggcttttt
     9901 atactaagaa attcttttaa atactaatag taaaagtcta tgacaaaaca gaagaaattt
     9961 ttgacctgtg atggtaatca ggctgctgct catatttcat atatgttcag cgaagtagcc
    10021 gctatctatc ccatcactcc gtcgtctaca atggcagaat atgtagacga atgggctgcc
    10081 gccggacgta agaatatttt cggcgaaacg gttttggtac aggaaatgca atcagaaggt
    10141 ggtgctgcag gtgcagttca cggttctttg caagctggtg ccctgacttc aacttacacg
    10201 gcttctcagg gattgttgct gatgatccct aacatgtaca agattgccgg tgagttgctt
    10261 ccttgcgtat tccatgtatc tgcccgtaca ctggcatctc atgccttgtg tattttcggc
    10321 gatcatcagg atgttatgtc tgctcgtcag actggtttcg caatgttggc agaaggttct
    10381 gttcaggaag ttatggactt ggcgggtgta gctcacctgg ctactatcaa gtctcgcgtt
    10441 cctttcgtga acttcttcga cggtttccgt acatctcacg aaatccagaa gatcgaagct
    10501 ctggaaaatg atgacctggc tccgctgatc gaccagaagg cgttggctga attccgtgca
    10561 cgtgctttga atccggaaaa accggaagct cgcggtatgg ctgaaaaccc ggatcacttc
    10621 ttccagcaca gagaatcttc aaacaaatac tatgaagcag ttcctgctat cgtagaagaa
    10681 tatatgaacg aaatctccaa gctcacaggc cgtaaatatg gtttgttcga ttactacgga
    10741 gcagaagatg cagaacgcgt gattatcgca atgggttctg taaccgaagc tgcccgcgaa
    10801 gctatcgacc acctgactgc tcagggtgaa aaagttggtt tggtttctgt tcatttgtat
    10861 cgtccgttct cagctaagca tttcctggca gctgttccta agactgcaaa acgtatcgca
    10921 gttcttgaca gaacaaaaga accgggtgca actggcgaac ctttgtatct ggatgtaaaa
    10981 gactgtttct acggacaggc tgacgctccg gttatcgtgg gtggccgtta tggtttgggt
    11041 tctaaagata ctactccggc acagatcatc gctgtatacg aaaacctggc attgccgatg
    11101 ccgaagaacc agttcacact gggtatcgta gacgatgtta cattcacttc tcttcctcag
    11161 aaagaagaaa tcgctttggg cggcgaaggt atgttcgaag ctaagttcta cggattaggt
    11221 gctgacggta cggttggtgc taacaagaac tctgtaaaga ttattggtga caatacaaac
    11281 aaatattgcc aggcatactt ctcttatgat tctaagaagt ctggtggttt cacttgttct
    11341 cacctgcgtt tcggtgatca tccgattcgt tcaacttatt tggtaaatac tccgaacttc
    11401 gttgcttgtc acgttcaggc ttatctgcgt atgtacgatg ttactcgcgg tttgcgtgaa
    11461 aacggtacat tcctgttgaa cactgtctgg aatggcgaag agttggctaa acacctgccg
    11521 aacaaggtga aacgttattt cgctcagaaa aatattactg tttactatat caatgcaaca
    11581 cagattgctt tggaaattgg tttgggcaac cgtaccaata caatccttca gtctgcattc
    11641 ttccgtatca caggtgtaat tcctgttgat ttggctatcg aacagatgaa gaaattcatc
    11701 gtgaagtctt acggaaagaa gggtgaagat gtagttaaca agaactatgc tgctgtcgat
    11761 cgtggtggcg aatatactca actgacagtt gatccggact gggctaacct gccggacgat
    11821 gaagttgtag caaacaacga tcctgctttc atcaacgaag tagttcgtcc tatcaatgct
    11881 caggatggtg acttgctgaa ggtttctgca ttcgaaggta tcgaagacgg tacatggcat
    11941 cagggaacag ctaaatatga aaaacgtggt gtagccgctt tcgttcctgt ttgggaaccg
    12001 gataactgta tccagtgtaa caagtgtgcg tatgtttgtc ctcacgcttc tatccgtccg
    12061 ttcgtgttgg atgctgctga acaggctgct gctccgttca ataactcttt gaaagcaaca
    12121 ggtaaacaat tcgaaggaat gcagttccgt attcaggtag acgttcttga ctgtctgggt
    12181 tgtggtaact gtgccgatgt ttgtccgggt aatccgaaaa agggtggtaa agcacttaag
    12241 atggctgctt tggaaactca attggatgaa gctccgaact gggatttctg tgctgaaaag
    12301 gtgacaacaa aacaacatct ggttgacatc aaggctaacg tgaagaactc tcagtttgca
    12361 actccgttgt ttgagttctc cggtgcttgc tccggttgtg gtgaaactcc gtacgtgaag
    12421 ttggtaactc aactgttcgg tgaccgtgaa atggtagcta acgcaacagg ttgttcttct
    12481 atctattcag gttcagtacc ttctactcct tatacaacaa atgataaggg tcaaggtccg
    12541 gcttgggcta actcattgtt cgaagacttc tgcgaattcg gtctgggtat ggaactggct
    12601 aacgaaaaga tgcgtgcacg cctgacaaat gcgatgaacg aaattatcgc tgccgacaat
    12661 gctcctgctg aagctaagga agttctgaag gcttgggttg aaaatcagaa tgatgccgat
    12721 aagacaaaag aactggctcc tcaggtattg gctattgctg aagaaggtat cactcacggc
    12781 tgtccgctta gcgcacagat caaggagctt tctcacttcc tggtaaaacg ttcacagtgg
    12841 attatcggtg gtgacggtgc ttcttacgat atcggttacg gtggtcttga ccatgtaatt
    12901 gcttcaggta agaacgttaa catcctggta ttggatactg aagtttattc aaatacggga
    12961 ggtcagtctt ctaaagctac tccggtaggt gcaatcgcta agtttgctgc ttccggtaag
    13021 agaatccgca agaaagacct gggtctgatg gctacaactt acggttacgt ttatgttgct
    13081 cagatcgcaa tgggtgccga ccaggctcag acgttgaaag caatccgcga agctgaagct
    13141 tatgatggtc cttcattgat cattgcttat gctccttgta tcaaccacgg tttgaagaag
    13201 ggtatgggta agagccagca ggaagaagct gatgctgtag catgtggtta ctggcatttg
    13261 tggcgttaca acccggcttt ggaagaagaa ggcaagaatc cgttctcttt ggatagcaaa
    13321 gaaccggatt ggagcaaatt ccaggacttc ctgaagggtg aagtacgttt cgcatctctg
    13381 acaaaacaat tcccggcaga agccgctcaa ttgttccagg ctgccgaaga caatgctaag
    13441 tggagactta acaactacaa gcgtttggct aaacagcagt ggggtgttga agaataattg
    13501 attatttgat catctaaata gtaaaacgga atcttcgaaa gagggttccg tttttttgta
    13561 taagccaaat aaatcgtacc tttagcgaaa ctaaacaaac aagcaaatgg cgaaaaataa
    13621 aagcaagcag aatcagtttc agttactctc tcctgaaaag tatattcgtt tgaaagctag
    13681 aaatttaccg atagaggtgt gttatgtctc cgatgactgg aaagatgaaa gaggggctgt
    13741 agcggaagtg atcgtagttc gtcgtcatgc cggtggaaat tatacattcg gagtttacgt
    13801 cgtagatacg ttgtgtctgg gagtgaaaca ttctgtatat aggtttaatg tgccaccgga
    13861 tgagtatgac gattttgttg aaagaacggc cactgattgc ggtattaaaa tcagttataa
    13921 tgaagctcat aattttattt atggagctat agcgtttgcc gaagagttcg ggatcaaacc
    13981 ggataagagt tttgccctga cgcaatatat actggaagag gatacggaag agattccttt
    14041 gattgaatat aaatatggga gaggtggccg ccctcacctg gttgtcgaaa cttctcttga
    14101 ggcaagtaaa tatatcccta tactggaaga atccacagg
//
