LOCUS       c00003_gnlPro..        14417 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IDJHALKJ_3.
ACCESSION   c00003_gnlPro..
VERSION     c00003_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 08:12:06
            Original ID  :: gnl|Prokka|IDJHALKJ_3
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14417
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..693)
                     /locus_tag="ctg3_1"
                     /transl_table=11
                     /translation="MLQRKMLSFLFMMIFIPSVRAQWKDSTRFINKEHEFETTYNKISE
                     NKVYQMLRVPVPLFAISAITYGQGDKFRTLRNTHTPNFHYRYDDFLQYTPLLAVYGMKL
                     GGVESRSSWPRMIVSNAFSATIMAATVNSMKYTIKRERPDGSKNNSFPSGHTATAFMAA
                     TIMHREYGLTRSPLYSIGGYTVATATAFSRQLNNRHWLSDVLAGAGIGILSTELGYFLA
                     DLIFKDKGL"
     protocluster    1..14417
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[931:4417]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      932..4417
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14417
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14417
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             932..1657
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_2"
                     /sec_met_domain="SucD_FumR (E-value: 4.7e-76, bitscore:
                     245.5, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLLNSSIGKKLIMSVSGLFLVLFLLFHLSMNVAAAFSGEAYNMI
                     CSLLGANWYAVAATLVLAAGVVIHFVYAVLLTLQNRKARGNDRYAINARPKGVEWASQN
                     MLVLGIIIILFMVLHFSQFWYKMMFAELLGNHMVTLCDGTTTVSPQDGAAFINYYFQGN
                     ILNTVLYLVWYVALWFHLTHGFWSAIQTIGWSNTIWMNRWICISKIVATVICVVFAIIT
                     IVFYLNGVGGDYVAVCAGH"
     CDS             1691..3634
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 195.7; E-value:
                     4.7e-60)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 2e-60, bitscore:
                     195.7, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 2e-38, bitscore:
                     122.1, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQIDSKIPQGPLAEKWKNYKDHQKLVNPANKRRLDVIVVGTGLA
                     GASAAASLAEMGFNVLNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTIKG
                     GDYRAREANVYRLAEVSNSIIDQCVAQGVPFAREYGGLLDNRSFGGAQVSRTFYARGQT
                     GQQLLLGAYSALSRMIGLNKVKMYTRHEMLDVVKVDGRARGIIARNLITGQIERFSAHA
                     VVVATGGYVNTFFLSTNAMASNGSAAWQCYKKGAYFANPCMVQIHPTCVPVKGDYQSKL
                     TLMSESLRNDGRIWVPKKLEDAKALQAGTKKGKDIPEADRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSDAINRLGKDVVKAKYGNLFDMYEEITNDDPYE
                     TPMMIYPALHYSMGGLWVDYELMTSIPGLFAIGEANFSDHGANRLGASALMQGLADGYF
                     VLPYTIQNYLSDQIQVPRFSTDLPEFAEAEKGIKDRIKKLMSIKGKESVDSIHKKLGHI
                     MWEHVGMARDAKGLQEAIQMLKELKKEFWSNVYIPGEADNLNVELDKALRLADFIEIGT
                     LMAHDALDRAESCGGHFRTEHQTEEGEALRHDDKFMYVSCWEYQGEDKDPVMLKEDLNY
                     QFVVPQTRNYKK"
     CDS             3662..4417
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_4"
                     /sec_met_domain="Fer2_3 (E-value: 1.8e-26, bitscore: 83.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 6e-12, bitscore: 36.8,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6.4e-06, bitscore: 17.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKDIKVTLKVWRQKSPKDKGQFETYQIDKINQSVSFLEMLDILN
                     ERLVSEGKEPIVFDHDCREGICGMCSLYVNGHPHGPATGATTCQLYMRRFNDGETITIE
                     PWRSAGFPVIRDLMVDRYAYDKIIQAGGFVSVNTGGVPDANSIAIPRADAEMAMDAAAC
                     IGCGACAAACKNGSAMLFVSAKVSQLALLPQGKVEAARRAKAMVAKMDELGFGNCTNTR
                     ACEMECPKNISVSNIARLNREFICAKLQD"
     CDS             complement(4565..4705)
                     /locus_tag="ctg3_5"
                     /transl_table=11
                     /translation="MPDANPYKQLKPVSRQALTNFVNLKSNTIMKKPQYKDTGILQLVN
                     S"
     CDS             complement(4716..5561)
                     /locus_tag="ctg3_6"
                     /transl_table=11
                     /translation="MEDNIPKFDLPVDFIVGNSITGEILNQYGRFPCKIKAGIFVLCVQ
                     GTVHATVNLTEFTIRKNDFITLPPGCFIQIHEVSDDVKLCFAGFSSVFVSHINYIKTIT
                     NYLPVIFDSPIMPLPEHISLLYQQAFDLLINAYSMPKTIENKEIIKAIFTIFMQGVIEL
                     YRNHTPYSNAPMTRNMEICREFVQLAMENYTKEHSVSYYAKRLNITLQHFCYVIKKVSG
                     RTALDILSNIIIMDAKAQLKSTDMPVKKIAFALGFDNLSFFNKYFRQHVGMTPQEYRES
                     "
     CDS             5907..7016
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Radical_SAM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_7"
                     /sec_met_domain="Radical_SAM (E-value: 1.4e-09, bitscore:
                     29.4, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MCFYAEDMDKKEKDLTFEEIKTISETAGQFNRLWVSGGEPTLREE
                     LPEIIEMFYKNNEIKDVNIPTNGLKPDRIVAWVKQIRQNCPELNINLSLSLDGFGDTHD
                     IQRGVPGNFYKAMGTLKLIEKNFADDGRVLKNLATVITKYNENEVEDLMIWMLGRFHLS
                     NHIIEAARGMTRDDGVKVLTEPTLRALQDKVVPIYNVYGERMAEETGGFRKPIARFFYL
                     GFIRTLYNVRATNIDHPTPWGMDCTAGETTLVIDYDGRFRACELREPLGNVKDYDCNIA
                     KIMESDAMKQEIAAIGHGDKANCWCTHGCWITSSLVFNPRKMITQVYKGYREMKKLNRP
                     LNISEELLQSIERKYALDEQKLVELGVRN"
     CDS             7194..7778
                     /locus_tag="ctg3_8"
                     /transl_table=11
                     /translation="MTTKLKDLFDTFLNIAASSQKLGINLIRVAILIIFVWIGGLKFYN
                     YEAEGIVPFVANSPFMSFFYAKSAPEYKEYKLKEGEFNEAKHQWHVENNTYIFSHGLGI
                     MIMAIGILTFLGIFSPKIGLIGSGLAIIMTLGTLSFLVTTPEVWVPDLGSGEHGFPLLT
                     GAGRLVIKDTAIIAGAIVVLSDCAQRILKKK"
     CDS             complement(7897..8046)
                     /locus_tag="ctg3_9"
                     /transl_table=11
                     /translation="MPYLKEKRLAFPNANPYKQLKPVSRQALTNFVNLKSNTIMKKPRC
                     KYTA"
     CDS             complement(8202..8348)
                     /locus_tag="ctg3_10"
                     /transl_table=11
                     /translation="MSPGNTPYTYIHYKHLPGYNDMKKIIRDHACVPHDPYDPHYNKRD
                     GPK"
     CDS             8361..8933
                     /locus_tag="ctg3_11"
                     /transl_table=11
                     /translation="LITFLVGAAFLLPRLGWMDSDWLQVYWPAAFVIVGLMLIFEPRKK
                     NSYHYNSRREDTGGEDIRGNAVAGKVKSDFINTDGYVESDNTFGYVEQIILDPVFKGAR
                     IRTVFGGTVLDLRKTKLDSAKTYIDIDCKFAGVEIYLPGDWAVNFHGSPIMGACEDKRF
                     NASMEMDKEHILVVRGIVMFGGIEFKS"
     CDS             9020..9742
                     /locus_tag="ctg3_12"
                     /transl_table=11
                     /translation="LLLYYYGHTGWLVAWLDSLVSVGIFCVSGFLFWYVTGILRPLQAQ
                     IALAVGVLIISVTGGYMAGALVYPDRMDWFASTIPFRILLGLLGWIILAQWYYIRWKEL
                     QMEIQEEQRKEENAPAETGVSSPEEEAILDRISVKDGSRIHLIHLEELLYIQASGDYVA
                     LFTTDGQYIKDQTMKYFESHLPANLFIRIHRSCIVNSEQIMRVELFGKESYQVRLKTGV
                     CLRASLTGYKLLKERLSL"
     CDS             10034..11263
                     /locus_tag="ctg3_13"
                     /transl_table=11
                     /translation="LQAMEYIGLHEDKISLADIIKYLSLLKGNMDELNLLEFKTIKGWL
                     VYSLSLVLLLCIPCVIILLITGLLSGNIDSGLLLAVSFIPFLFILPLTLLLTFINNYRK
                     PKKLRELMQTVLMRYEWDGPINQTGRLQLECRKDHFLFRTEVLRQMNPKGRNVSLIFIS
                     VPFYVPIEKELIHAEDIIAYLKGKSLFVIEPDMACLGMSFKMFQKLDLREDIDQLIYVM
                     KRFSLRPGTLFKAQDITLKVPETLEIQALFIFGQKIDQRFLNWANLMLDAGFVSDNMKI
                     MAEQASLTLPQKELKKRVEVIFLEFNLYFSKETVLNNYLIFLILEEQEERRSVLEIIQC
                     LASLYQSSRLPLLQEYDLLYKAKRALDETGEQNFWTADPPLTVDNVDTYILTYLTRRLA
                     DLIASREKDQ"
     CDS             11442..13646
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_36C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_hydro_36N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Melibiase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_14"
                     /sec_met_domain="Glyco_hydro_36C (E-value: 4.8e-21,
                     bitscore: 66.0, seeds: 330, tool: rule-based-clusters)"
                     /sec_met_domain="Glyco_hydro_36N (E-value: 6.6e-49,
                     bitscore: 157.5, seeds: 284, tool: rule-based-clusters)"
                     /sec_met_domain="Melibiase (E-value: 2.8e-125, bitscore:
                     408.6, seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKALLLTVALLLGCVTVSSQDKDTGIITVSTNDLSMVFSISPDKK
                     VVYNYFGDKFQDVSPFLHKKYKEQPDNGIGYAPVIYPAYGGRFFLNPALKLTHDDGVQT
                     TELIYAAHQVKNIDNNRIETVIQLKDPLYPVFVNLNFTAYQKENVICQSVSISHQEKNK
                     LAVENIASAYLPLHADSYYLTHFHGAWASEMQLVEEQLTPGVKRVESKKGIRTTQSENS
                     SFLLSLNGPANEDMGEVYAGSLAWLGNYLSSFEIDECGLLHVMSGMNDFASTYNLEPGK
                     TLQTPEMVWTYSSTGKGQVSRNLHDWSRNYALAHGDQELPIVLNSWEGAYFDFNEKTIT
                     DMIDDAAAFGVEMFVLDDGWFGNKYPRNSDKVGLGDWQVNRKKLPRGIDYLAKHAVSKG
                     LKFGIWIEPEMVSPKSELAEKHPEWIVKSGKRDIIPMRNQWLLDLSNPEVQDFVVKTFD
                     EVIALSPDISYIKWDANRHVDNFGSEYLSKENQTHFWIDYTKGLYSVYERIRAKHPDVL
                     IQLCSSGGGRLDFGALKYHDEFWASDNTNSLDRIFIQYSTNLFFPAKATAAHVSTTPNH
                     QTGMMAPLKFRFDVAMTGRLGMELQPEDLTGDELPFAEQAIKNYKRIRPIVQFGDLYRL
                     KSPYDGTGWASHMYISKDKKESVFFAYSLKYHGRTTFFETRLKGLDPAKMYKITELNKA
                     GNSTFYGDGQVFPGDYLMKAGISLTIGNTYESTVLLITEQ"
ORIGIN
        1 caagcctttg tccttgaaga tcaggtctgc cagaaaatac cctaactctg tggataagat
       61 gccgataccg gccccggcca gtacgtcgct cagccagtgg cggttgttca gttgccggct
      121 gaaagcggtg gctgtggcga ctgtatatcc cccgatacta tataacgggc tgcgggtcag
      181 accatattcc cggtgcatga tggtagcagc catgaaagcg gttgccgtgt gtcccgaagg
      241 gaatgagttg ttctttgagc cgtcggggcg ttcgcgtttg atcgtatatt tcatgctgtt
      301 gacggtagcg gccatgatcg ttgccgaaaa agcgttcgat acgatcatcc ggggccatga
      361 actacgactt tccacaccgc cgagcttcat cccgtaaaca gcaagcaacg gagtatattg
      421 cagaaaatca tcgtatctgt aatggaagtt gggcgtatgc gtattgcgca atgtccggaa
      481 tttatcgccc tgcccatatg ttatggctga aatggcgaaa agaggaacag ggacacgcag
      541 catctggtat accttattct ctgatatttt gttgtaagtg gtttcaaatt catgttcttt
      601 atttatgaat ctcgtactat ctttccactg agcacgaaca gacggtataa aaatcatcat
      661 aaataagaag ctcagcattt tacgttgtaa catacgatcc cctgattatg ccacgaagat
      721 ataaaaatgc cggttagtac tggttacatt ttcgttaatt tatttattga ataggattta
      781 ccgtttgtcc ctcctgaaat gtataggttt gattggcgaa atatttcttt aatcgtttgc
      841 gtgatacgtg tatttagcat acctttgcct gataattgag tatattgata tgaatttcta
      901 aaaacaatta aataacttaa attattatct tatgtggtta cttaattctt ctatcgggaa
      961 gaagctgata atgagtgtat caggcctttt tcttgttttg ttcttattgt tccacttgtc
     1021 aatgaatgtg gcggctgctt tctcgggaga agcctataac atgatttgtt cattgttggg
     1081 agcaaattgg tatgccgtgg cagcaacatt ggtgctggca gcaggcgttg tgattcactt
     1141 tgtgtatgct gttctcctta cactgcaaaa ccgtaaggct cgcggtaacg accgttatgc
     1201 aattaacgct cgtccgaaag gtgtggaatg ggcatctcag aacatgctgg tactgggtat
     1261 tatcattatc ctgttcatgg tgttgcactt cagccagttc tggtataaga tgatgttcgc
     1321 cgaactccta ggcaatcaca tggtaacact ttgcgacgga acaacaaccg tatctcctca
     1381 ggacggtgca gcgtttatca actactattt ccagggtaat atcctgaata cagtgctgta
     1441 tctggtatgg tacgtagctt tgtggttcca cctgactcac gggttctgga gcgctattca
     1501 gactatcggt tggagtaaca cgatctggat gaaccgttgg atctgcattt ccaagattgt
     1561 agcaaccgtt atttgcgtag tgtttgctat cattactatc gttttctacc tgaatggtgt
     1621 aggtggtgac tatgtagctg tttgtgcagg acattaattt aaggtgtaac aatattgaaa
     1681 ataaatcatt atgactcaaa tagattctaa aatccctcag ggcccgttgg ctgagaagtg
     1741 gaaaaattat aaagatcatc agaaactggt gaaccccgca aacaaacgtc gtctggacgt
     1801 gattgtagtt ggtactggtc tggccggtgc ttctgctgct gcctctctgg cagaaatggg
     1861 attcaacgta ttgaacttct gtatccagga ttctccccgt cgcgcacact caatcgccgc
     1921 acagggtggt atcaatgctg caaagaatta tcagaatgat ggtgactctg tttaccgtct
     1981 gttctacgat acaatcaaag gtggtgacta tcgtgcccgc gaagcaaacg tttatcgtct
     2041 ggctgaagtt tccaactcta ttatcgacca gtgcgtagca cagggtgttc ctttcgctcg
     2101 cgaatacggt ggtctgctgg ataaccgttc attcggtggt gctcaggtat cccgtacgtt
     2161 ctatgcccgc ggtcagaccg gacagcagtt gttgctgggt gcttactctg ctttgagccg
     2221 tatgatcggt ttgaacaaag taaagatgta tacccgccac gaaatgctgg acgttgtgaa
     2281 ggtggatggc cgtgcccgcg gtatcatcgc acgtaacctg atcacaggtc agatcgaacg
     2341 tttttctgct cacgcagtag tggtggcaac aggtggttat gtaaatactt tcttcctgtc
     2401 tactaacgca atggcttcca acggttctgc tgcatggcag tgctacaaga aaggtgctta
     2461 cttcgctaac ccttgtatgg tgcagatcca cccgacttgt gtaccggtga aaggtgacta
     2521 ccagtctaag ctgactttga tgtctgaatc attgcgtaac gacggtcgta tctgggttcc
     2581 gaagaaactg gaagatgcaa aagcattaca ggccggaact aagaaaggga aagacattcc
     2641 tgaagcagac cgcgactact atctggaacg ccgttatccg gcattcggta acctggttcc
     2701 gcgtgacgtg gcttcacgtg ccgctaaaga acgttgcgac gccggcttcg gtgtgaacaa
     2761 cacaggtctg gccgtgttcc tcgacttctc cgacgccatc aaccgtctgg gtaaagatgt
     2821 tgtaaaagct aaatatggta acttgttcga catgtacgaa gaaattacca acgacgatcc
     2881 atacgaaact ccgatgatga tttatcctgc attgcactac tcgatgggtg gtctgtgggt
     2941 tgactatgaa ttgatgactt ctattccggg tctgttcgct atcggtgaag ctaacttctc
     3001 tgaccacgga gctaaccgtc tgggtgcttc tgcgttgatg cagggattgg ccgatggcta
     3061 ctttgtattg ccttatacaa ttcagaacta tctgtcagac cagatccagg ttccacgttt
     3121 cagcaccgac ctgcctgagt ttgcagaagc tgaaaagggg atcaaagacc gcatcaagaa
     3181 attgatgagt atcaagggta aagagtcggt agattctatc cataagaaac tgggtcatat
     3241 catgtgggaa catgtaggta tggcacgtga tgcaaaaggt ttgcaggaag cgatccagat
     3301 gttgaaagag ctgaagaaag agttctggag taatgtatat attccgggtg aagccgataa
     3361 cctgaacgta gagttggata aggcattgcg tttggctgac tttattgaga ttggtacatt
     3421 gatggcacac gatgcattgg accgtgccga atcttgtgga ggacacttcc gtacagagca
     3481 ccagaccgag gaaggcgaag ccctgcgtca tgacgataag ttcatgtacg tatcttgttg
     3541 ggaataccag ggtgaagaca aagatccggt tatgctgaag gaagatttga actatcagtt
     3601 cgttgttcct caaacacgta actacaagaa gtaataatca tcaatcacaa aaattagaat
     3661 catggataaa gatataaaag taacacttaa agtttggcgt cagaaaagtc cgaaagataa
     3721 aggacaattt gagacttacc aaatagacaa aatcaatcag agtgtttctt tcctggaaat
     3781 gttagacatt ttgaatgaac gtttggtcag tgaaggtaaa gagccgatcg tattcgatca
     3841 cgactgtcgt gaaggtatct gcggtatgtg ttctttgtat gtaaacggac atccgcacgg
     3901 acctgcaacc ggcgcaacta cttgccagct ttatatgcgt cgcttcaatg atggcgaaac
     3961 tattacaatc gaaccgtggc gttctgccgg tttcccggta atccgcgact tgatggtaga
     4021 ccgttatgct tacgataaaa ttatccaggc aggtggtttc gtatcagtga acacaggtgg
     4081 tgtacctgat gccaattcaa tcgctattcc tcgtgcagat gctgaaatgg ctatggatgc
     4141 tgctgcatgt atcggttgcg gtgcttgtgc tgctgcttgt aagaacggtt cggctatgtt
     4201 gttcgtttct gcaaaggtta gccagttggc tctgttgcct cagggtaagg tagaagctgc
     4261 tcgtcgtgcg aaagcaatgg ttgccaagat ggacgaactg ggcttcggta actgtaccaa
     4321 cacgcgtgct tgcgaaatgg aatgtccgaa gaacatctct gtcagcaaca tcgctcgttt
     4381 gaaccgcgag ttcatttgtg ctaaattgca agactaatat acattatata tgtatgtccg
     4441 gagaggcgtt gcttatggca gcgcctcttc ttttttgccc ctattttaac atttctgaag
     4501 tcatagataa atatcttgaa tgttgttagt gtttcttata tgctatacaa cactaattag
     4561 cattttaact attgacaagt tggagaatac ctgtatcttt gtactgtggt tttttcataa
     4621 tagtattaga tttaaggtta acaaagttgg ttagggcttg tcgtgagaca ggctttaatt
     4681 gtttataggg gtttgcgtcc ggcatatccc tttttttagc tctccctgta ttcctgcggg
     4741 gtcattccta catgttgccg gaaatatttg ttgaagaacg aaaggttgtc gaaacccagg
     4801 gcgaatgcaa ttttcttgac cggcatatcg gtcgatttaa gctgcgcttt ggcatccata
     4861 atgatgatat tgctcaggat atccaatgca gtccgtccgc tgaccttttt tatcacataa
     4921 cagaaatgct gcaaggtgat gttgagcctt ttggcgtaat aagacacgct atgctctttc
     4981 gtgtagtttt ccatcgccag ttgtacgaac tcccggcata tttccatgtt acgcgtcatg
     5041 ggagcattgc tatatggcgt atgattcctg tataattcaa taaccccttg catgaagata
     5101 gtaaagattg ccttgataat ctccttgttc tcgatggttt taggcatgga ataagcattg
     5161 atcagcaagt cgaaagcctg ttggtagagt aaggatatat gttccggcag aggcatgatc
     5221 ggactgtcga atatgacagg cagatagttc gtaatcgtct ttatataatt gatatggctg
     5281 acgaatacgg aagaaaagcc tgcaaaacac agttttacat catcggaaac ctcatgtatc
     5341 tgaatgaagc aacccggggg taaggtgata aagtcgttct tccggatggt aaactcagtt
     5401 aagtttacag tcgcgtggac tgtcccttgt acgcaaagca cgaatatgcc agccttgatc
     5461 ttgcacggga aacgtccgta ctggttcagt atttcacctg taatactgtt tcctacaata
     5521 aaatctacgg ggaggtcgaa tttaggaata ttgtcttcca tacttttata tacacttaat
     5581 tgaatgtaca aagatagttt ttttgagaca agttagtcga taatcttaaa tatagaacat
     5641 cgaatcccac aaatggagat tgttttgtgc tgtataatag ttgaaatttg cgaatgtttt
     5701 caagtcttgc tgatagattt gttgggatgg tatatatttg tctatctgct aaataagata
     5761 tgggagctaa tactaataga gaaatctaat cgataataac aatgagtacg aaaagaacaa
     5821 agagctcttt caggacaatg agcacaaaca gaaaattaga atctgttttc ctgtttgtca
     5881 caggacggtg taatgctaaa tgtaaaatgt gtttctatgc agaagacatg gataaaaagg
     5941 agaaagacct gacttttgaa gaaatcaaga caatctccga aacagccggg cagttcaacc
     6001 gtttgtgggt atccggcggt gaaccgacac tgcgtgagga gttacctgaa attatagaga
     6061 tgttctacaa gaataacgag ataaaggacg tgaatatccc taccaacgga ttgaagcctg
     6121 accggatcgt cgcctgggta aaacagatcc gccagaattg tccggaactg aatatcaacc
     6181 tgagcctttc tttggacggt ttcggtgata cgcatgatat acagcgcggc gttcccggca
     6241 atttctacaa agcgatgggg acactgaagc tgattgaaaa aaactttgct gacgacggca
     6301 gggtgttgaa aaacctggcc accgtaatca ccaaatataa cgagaatgag gtcgaggatc
     6361 tgatgatatg gatgctggga cgtttccatc tttccaatca tattattgaa gctgcacgcg
     6421 gtatgacccg cgacgacgga gtgaaggttc ttaccgagcc tactctacgc gccttgcagg
     6481 ataaggttgt tcctatttat aatgtatatg gggagcgtat ggcggaggaa accggtgggt
     6541 tcagaaaacc tatcgcccgt ttcttctacc tgggtttcat acgtacatta tataatgtac
     6601 gtgcgaccaa tatcgatcat ccgacaccct ggggtatgga ttgtacggcc ggcgaaacaa
     6661 cactggtaat agactatgac ggtcgtttcc gtgcctgtga acttcgcgaa ccgctcggta
     6721 atgtcaagga ttatgactgc aatatcgcaa agattatgga gagcgatgcc atgaaacaag
     6781 agattgccgc tatcggtcat ggtgacaagg ctaactgctg gtgtacgcat gggtgttgga
     6841 tcacttcatc gcttgttttc aatccccgca agatgatcac gcaggtctat aaaggatacc
     6901 gggagatgaa gaagctgaac cgtcctctga atatcagtga agagcttttg cagagtatcg
     6961 aacgcaaata tgccttggac gaacagaaac tggtggagct gggagttcgt aattaaaata
     7021 gttccgataa cggatcattt ataaagccgg ttgacgggaa atatacctct gttaaccggc
     7081 tttattgtgt ttaagggaat aattgtcaaa ttatccggta gaattgccat ttcccatagg
     7141 ggaaaaatgt cggatctttg catcataagt taaactgata aacaaagaaa gacatgacta
     7201 ctaaattaaa agatttattc gacacatttc tgaacattgc agcttcttca cagaaactgg
     7261 gtattaacct gatccgcgta gctatcctga ttatattcgt atggatcggc gggctgaaat
     7321 tctataatta tgaagcggaa gggatcgttc cttttgtggc aaacagtccg tttatgagct
     7381 ttttctatgc aaagagtgca ccggaataca aagaatataa gttgaaagaa ggtgaattca
     7441 atgaagccaa gcatcagtgg catgtagaaa acaataccta tattttttca catggactag
     7501 gcattatgat catggcgatc ggtatcctga ctttcctggg tatcttttct ccgaaaattg
     7561 gcttgatagg ttccggactg gcgatcataa tgacattggg tacgctttca ttcctggtga
     7621 caacacctga agtgtgggtg cccgatttgg gaagcggaga acatggtttc cccttactga
     7681 ccggagcagg tcggctggta ataaaagata cggcaatcat agccggagcg atcgtggtat
     7741 tgtccgactg tgcacaacgt atattaaaga agaaatagga ataaaaagtg tttattttaa
     7801 cactttggaa gcaaaaaaca aacatattga accttgttag cttttcttat agtgtatgaa
     7861 acaccattta gcataaaacc tcttgacagg tttggattaa gcagtatatt tgcatcgtgg
     7921 ttttttcata atagtattag atttaaggtt aacaaagttg gttagggctt gtcgtgagac
     7981 aggctttaat tgtttatagg ggtttgcatt cggaaatgca agcctttttt cttttaaata
     8041 tggcattctc tgaaaaataa ctcccttttt tatcggtaat attcggcaat tcaccgatat
     8101 ttgactgtaa taggacgtat ttctattgcc ggaaggctga caggagcata cttttgctct
     8161 caaacaatta aactgtatat cgtatgaatc ttaggaaaaa cttattttgg gccatcccgt
     8221 ttattgtagt gggggtcgta tggatcatga ggaacacagg catgatcacg gatgatcttt
     8281 ttcatatcat tgtatcctgg cagatgcttg taatgtatat aggtataggg agtatttccc
     8341 ggagacatta tataggcggt ttgattacct ttttggttgg tgcggcattt ttactgccac
     8401 gactggggtg gatggatagc gattggttgc aggtctattg gccggctgct tttgtcattg
     8461 tcggtttaat gctgatcttc gaaccgcgta aaaagaactc ctatcattac aatagccgga
     8521 gagaggatac cggtggagaa gatatccggg gaaatgccgt tgccggtaaa gtaaaaagtg
     8581 attttattaa tacggacgga tatgtggaat cggataatac atttggctat gtggaacaaa
     8641 ttattttaga tccggtattt aaaggagcca ggattaggac tgtgtttggg ggaacggtcc
     8701 tggatttgcg gaaaacgaag ctggatagtg ctaaaaccta tattgatatc gattgtaagt
     8761 ttgccggtgt ggaaatctat cttcctgggg attgggcggt caattttcat ggcagtccga
     8821 tcatgggggc atgcgaggat aaacgtttta atgcctctat ggaaatggat aaagaacata
     8881 tactggttgt acggggaatt gttatgttcg gtggcattga atttaagagt tgattatgca
     8941 gacacatccg tttataaatt ctgtcctgtg tagaatggct ggtgtggctt tggctgtggt
     9001 cagttgcagc ataagcgcct tgctcctcta ttattacgga catacgggat ggcttgtcgc
     9061 atggttggat agtctggttt cggtcggtat attctgtgtc tccggtttcc tgttctggta
     9121 tgtaacaggc atattgcggc cattacaggc ccagattgca ttggctgttg gcgtccttat
     9181 catatccgtt accggaggat atatggccgg ggcgctggtt tatccggata ggatggattg
     9241 gtttgcatct accattccgt tccgtatttt gttgggtttg ctgggatgga ttattttggc
     9301 ccagtggtat tatatccgtt ggaaggagtt gcagatggag atacaggagg aacagagaaa
     9361 agaagaaaat gctccggcgg aaacaggcgt atcgtcaccg gaagaggaag caatactgga
     9421 tcgcatctct gtgaaggatg gcagccgtat ccatctgatc cacctggagg agttacttta
     9481 tatccaggcc agcggtgact atgtggcact cttcacgacc gacggacagt atataaaaga
     9541 tcagacaatg aaatattttg aatcgcatct gccggcaaac ctgtttatcc gtattcaccg
     9601 ttcctgtatc gttaatagcg aacagatcat gcgtgtggaa ctgttcggca aggaaagtta
     9661 ccaggttcgt cttaaaacag gtgtctgtct gcgtgccagc ctgaccggat acaagttgct
     9721 taaagaacgt ctttctctat agatttggct gttttaactg ttaaaattag cagtttttgt
     9781 ctgtattgta taaagttttg tgttcggaaa caatttttag ctacaatgcc cgaaaggctt
     9841 aacatatatt gtctgtaaaa gacttgacaa acgcttgttt caggcttatc tttgtactgt
     9901 ggttttttca taatagtatt agatttaagg ttaacaaagt tggttagggc ttgtcgtgag
     9961 acaggcttta attgtttata gggggttctt ttctcatcat tttgtatgaa tctttgattt
    10021 tgaggtgtta tctttgcaag ctatggaata tataggactg catgaagata aaatatcact
    10081 tgctgatatt ataaaatatc tttctctttt gaaaggtaat atggatgaat tgaatttgct
    10141 tgaattcaaa accattaaag gttggttggt ttattctttg tcattagttc ttttgttgtg
    10201 tataccttgt gtaatcattt tattaataac aggtctttta tccggaaata tagatagcgg
    10261 attattattg gctgtttctt ttatcccttt cctctttatt ttgcctttga cattgttatt
    10321 gactttcatc aacaattaca gaaaacccaa aaagttgagg gaactaatgc agacggtttt
    10381 gatgcgttac gaatgggatg gtcctatcaa tcaaaccgga cggttgcagt tggaatgcag
    10441 gaaggaccat tttctgttta gaacggaagt tttgcggcaa atgaatccca aagggcgtaa
    10501 tgtgtctttg attttcatat ccgttccttt ctatgtaccg atagaaaagg agctgataca
    10561 tgccgaagat ataattgctt atctgaaagg caagtctctt ttcgtgattg agccagatat
    10621 ggcatgtttg ggaatgtcgt ttaaaatgtt tcagaaactg gatttgcgtg aagatattga
    10681 tcagttgatt tatgtgatga aacgtttttc ccttcgcccc ggaacactct tcaaggcgca
    10741 ggatataact ttgaaagttc ctgaaacact ggaaatacag gcactgttta ttttcggtca
    10801 aaaaatagac caaaggtttc tgaattgggc taacctgatg cttgatgccg gatttgtgag
    10861 tgataatatg aaaattatgg ctgaacaagc atctctgact ctccctcaaa aagaattgaa
    10921 gaaaagagtg gaggtgattt tcctggagtt taatttgtat ttctctaaag agactgtatt
    10981 aaataattat ttgatattcc ttatactgga agaacaggaa gaacgaaggt ctgttttgga
    11041 gattatacaa tgtctggcca gtctctatca atcttccagg ctgcctctgt tgcaagaata
    11101 tgatctgtta tataaagcta aaagggcatt ggatgaaaca ggagaacaaa atttctggac
    11161 ggcagacccg cctttgacgg tcgataatgt ggatacttat atattaacct atttgaccag
    11221 aaggctagct gacctgatag cctctcgaga aaaggatcag tgatcgatca tccctttgta
    11281 acagatgcgt caaaaaatga cgtaaatgtt gcatttttat taaacctcta tgaattaagc
    11341 gcataattac aaataattgg cgagttcgtg ctttttgtgc tattgtttat tgatttagtt
    11401 tgcaccatca accttgaata agtaaaataa atttgataga catgaaagca ctattgttaa
    11461 ctgttgccct gctgctgggg tgcgtaaccg tttcctcaca ggataaagat acggggataa
    11521 ttaccgtctc tacaaacgat ctgagtatgg tcttttcgat ctctccggat aagaaagtag
    11581 tgtataacta ttttggcgat aaattccagg acgtttcccc tttccttcat aagaagtata
    11641 aagaacaacc ggataacgga atcggttatg ctccggtaat ctatccggct tacggaggac
    11701 gtttcttcct gaatccggca ttgaaactga cccatgacga cggcgttcag acaaccgaat
    11761 taatatatgc agctcatcag gtaaagaata tagataataa tagaatagaa acagtgatac
    11821 aattgaaaga tcctttgtat ccggttttcg ttaacctgaa cttcacggct tatcagaaag
    11881 aaaatgtaat ctgccagtca gtctccatat cccatcagga gaaaaacaag ctggctgtcg
    11941 agaatattgc ctccgcttat cttccccttc atgcagattc ttattatctg acccatttcc
    12001 acggggcctg ggcttccgaa atgcaactgg tagaagaaca actgacaccg ggtgtgaaac
    12061 gggtggaatc caagaagggg atacgtacta cccagtctga aaactcttct ttcctgcttt
    12121 ccctgaatgg ccctgccaat gaagacatgg gcgaagtgta tgccggctcc ctggcctggt
    12181 taggtaacta tctgtcttcc tttgagatag acgaatgcgg tttgctgcat gtcatgagcg
    12241 ggatgaatga ttttgcctct acttataatc tggaaccggg taaaacgttg cagactccgg
    12301 aaatggtctg gacatacagt tctaccggta agggacaggt atcgagaaac ctccatgact
    12361 ggtcgcgtaa ctatgcattg gcccatggag atcaggaatt gcctatcgtc ctgaatagct
    12421 gggaaggcgc ttatttcgat tttaatgaaa aaacgattac ggatatgatc gatgacgctg
    12481 ctgcttttgg cgttgaaatg ttcgtactcg atgacggatg gttcggaaat aaatatcccc
    12541 gcaattcgga taaggttggt ttgggcgatt ggcaggtgaa caggaaaaaa ctgccacgcg
    12601 gaatcgatta tctggcgaag catgcggtaa gtaaaggatt gaagttcggt atctggattg
    12661 agcctgaaat ggtaagtccc aagagtgaac tggcagagaa gcatccggaa tggatcgtca
    12721 agagcggtaa acgtgatata atcccgatgc gtaaccagtg gttactcgat ttgagtaatc
    12781 cggaggtaca ggactttgtt gtaaagacgt ttgatgaagt gatcgctttg tctcctgata
    12841 tctcttatat aaaatgggat gcaaaccgtc acgtggataa tttcggttcc gaatatctgt
    12901 ccaaagaaaa tcagactcat ttctggattg actatacaaa gggcttgtac agtgtttacg
    12961 aacggattcg tgcaaaacac ccggatgttc ttattcagtt gtgttcttcg ggtggcggcc
    13021 gtctcgactt cggtgcattg aaatatcatg acgagttctg ggctagcgat aacaccaatt
    13081 cgcttgaccg tatattcatc caatacagca caaatctttt cttcccggca aaggctacgg
    13141 ccgcccatgt ttcgactact ccgaatcatc agacgggtat gatggcgccg ctgaagttcc
    13201 gttttgatgt ggctatgaca ggccgcctgg gcatggagct gcaacccgaa gacttgaccg
    13261 gcgacgaact acctttcgct gagcaagcta taaagaatta taaacgtatc cgcccgatcg
    13321 tacagtttgg agacctctat cgcctgaaat ctccttacga cggaaccggc tgggcttcac
    13381 atatgtatat atctaaggat aaaaaggaat cggtgttttt tgcttatagc ctgaaatacc
    13441 acggacgtac aacattcttt gagaccagat tgaaaggact ggacccagct aaaatgtata
    13501 agatcacaga gttgaacaaa gccgggaaca gcaccttcta tggcgacggt caggttttcc
    13561 ccggtgatta tctgatgaaa gccggaatca gcctgacgat agggaatact tatgaaagta
    13621 ccgttctgtt gataacggaa caatgaaact atctataaat tatcaataca tgaaactcat
    13681 caatttaaat ctgctgctat tgctcgccct gcttgtatcc tgcggcgaat catccgtttc
    13741 ttcgggaaag tggacggtta gctatgacca ggtgcagaaa ggccaccgta tcgagaagga
    13801 gaaccagctt ctttccgatg gggtttatgc ctcctacaag ttgggtaata agttggtcac
    13861 gacccgtgac tacaaaaaga gcagttcgaa agtcaccgct atcagcgatg ctttcggtca
    13921 gggttcattg ttgcaggtga cctacacgga tagcaacctg cctacgcttg tacaatcttt
    13981 ctacatctat ccggagaaag attatctgct gacggaattt actcttcagg gaggagccgc
    14041 tgacgttgaa tcgaattata tggccccggt tactatcgac cgcatgccgg ccgtgttggc
    14101 tgaaggtgat aaccgcgcgt tattccagcc tttcgataac gattgctgga tacgttatca
    14161 gtctcatccg ctcactttcg atcaattacg tagctatgaa gtagcgactg tcttcaacaa
    14221 cgacgaccgt aaaggttttg tcatcggttc agtggaacac tccgactgga agaccggtat
    14281 cgatatgggg aaaggcgacc gtaataatat cggttcattg gtttgcttcg gcggcgttgc
    14341 cgattcgttg acacgcgact ctaaggcaca cggtgcttta aaaggaaaaa tggtaaagtc
    14401 tcctaaggta tttttcg
//
