Select genomic region:
Overview
1.1
3.1
3.2
31.1
32.1
34.1

### Identified primary metabolite regions

c00001_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_1)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 1.1 | TPP_AA_metabolism | Putative | 271,527 | 297,494 |

c00003_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_3)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 3.1 | Fumarate2succinate | SCFA | 2,582 | 26,052 | Fumarate to succinate B. thetaiotaomicron | SUC | 100%
Region 3.2 | Pyruvate2acetate-formate | SCFA | 132,957 | 155,932 | Pyruvate to acetate-formate E. coli | PFL_acetate | 100%

c00031_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_31)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 31.1 | OD_unknown | Putative | 1 | 23,037 |

c00032_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_32)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 32.1 | succinate2propionate | SCFA | 21,040 | 45,567 | Succinate to propionate B. theta | PRO | 50%

c00034_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_34)

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 34.1 | Rnf_complex | E-MGC | 27,934 | 52,994 | Rnf complex C. sporogenes | RNF | 83%

Region | Type | Class | From | To | Most similar known cluster | Similarity
--- | --- | --- | --- | --- | --- | ---
Region 1.1 | TPP_AA_metabolism | Putative | 271,527 | 297,494 |
Region 3.1 | Fumarate2succinate | SCFA | 2,582 | 26,052 | Fumarate to succinate B. thetaiotaomicron | SUC | 100%
Region 3.2 | Pyruvate2acetate-formate | SCFA | 132,957 | 155,932 | Pyruvate to acetate-formate E. coli | PFL_acetate | 100%
Region 31.1 | OD_unknown | Putative | 1 | 23,037 |
Region 32.1 | succinate2propionate | SCFA | 21,040 | 45,567 | Succinate to propionate B. theta | PRO | 50%
Region 34.1 | Rnf_complex | E-MGC | 27,934 | 52,994 | Rnf complex C. sporogenes | RNF | 83%

No primary metabolite regions were found in these records:
  c00002_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_2)
  c00004_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_4)
  c00005_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_5)
  c00006_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_6)
  c00007_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_7)
  c00008_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_8)
  c00009_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_9)
  c00010_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_10)
  c00011_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_11)
  c00012_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_12)
  c00013_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_13)
  c00014_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_14)
  c00015_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_15)
  c00016_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_16)
  c00017_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_17)
  c00018_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_18)
  c00019_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_19)
  c00020_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_20)
  c00021_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_21)
  c00022_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_22)
  c00023_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_23)
  c00024_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_24)
  c00025_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_25)
  c00026_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_26)
  c00027_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_27)
  c00028_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_28)
  c00029_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_29)
  c00030_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_30)
  c00033_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_33)
  c00035_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_35)
  c00036_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_36)
  c00037_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_37)
  c00038_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_38)
  c00039_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_39)
  c00040_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_40)
  c00041_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_41)
  c00042_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_42)
  c00043_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_43)
  c00044_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_44)
  c00045_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_45)
  c00046_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_46)
  c00047_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_47)
  c00048_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_48)
  c00049_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_49)
  c00050_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_50)
  c00051_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_51)
  c00052_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_52)
  c00053_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_53)
  c00054_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_54)
  c00055_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_55)
  c00056_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_56)
  c00057_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_57)
  c00058_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_58)
  c00059_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_59)
  c00060_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_60)
  c00061_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_61)
  c00062_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_62)
  c00063_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_63)
  c00064_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_64)
  c00065_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_65)
  c00066_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_66)
  c00067_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_67)
  c00068_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_68)
  c00069_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_69)
  c00070_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_70)
  c00071_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_71)
  c00072_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_72)
  c00073_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_73)
  c00074_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_74)
  c00075_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_75)
  c00076_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_76)
  c00077_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_77)
  c00078_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_78)
  c00079_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_79)
  c00080_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_80)
  c00081_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_81)
  c00082_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_82)
  c00083_gnlPro.. (original name was: gnl|Prokka|IPPPHGJP_83)

Compact view
c00001_gnlPro.. - Region 1 - TPP_AA_metabolism
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 271,527 - 297,494 nt. (total: 25,968 nt) Show pHMM detection rules used
TPP_AA_metabolism: (TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or PFOR_II))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00003_gnlPro.. - Region 1 - Fumarate2succinate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 2,582 - 26,052 nt. (total: 23,471 nt) Show pHMM detection rules used
Fumarate2succinate: (Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or Fer4_7 or SucD_FumR))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00003_gnlPro.. - Region 2 - Pyruvate2acetate-formate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 132,957 - 155,932 nt. (total: 22,976 nt) Show pHMM detection rules used
Pyruvate2acetate-formate: ((PFL_acetate1 or PFL_acetate2) and Radical_SAM)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00031_gnlPro.. - Region 1 - OD_unknown
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 1 - 23,037 nt. (total: 23,037 nt) Show pHMM detection rules used
Region on contig edge.
OD_unknown: (minimum(1, [PFOR_II, POR, POR_N]) and minimum(2, [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC, Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical or Gly_430_pcre or Gly_8-9_TMA))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.

No matches found.

c00032_gnlPro.. - Region 1 - succinate2propionate
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 21,040 - 45,567 nt. (total: 24,528 nt) Show pHMM detection rules used
succinate2propionate: (minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not Cytidylate_kin)

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.
c00034_gnlPro.. - Region 1 - Rnf_complex
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Download region GenBank file
Location: 27,934 - 52,994 nt. (total: 25,061 nt) Show pHMM detection rules used
Rnf_complex: (Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))

#### Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
resistance genes
encapsulation genes
electron transport genes
other genes
reset view
zoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
KnownClusterBlast
Similar known gene clusters
Shows clusters from the gutSMASH KnownClusterBlast database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
Click on reference genes to show details of similarities to genes within the current region.