LOCUS       c00145_gnlPro..         7214 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HMJEJMDP_145.
ACCESSION   c00145_gnlPro..
VERSION     c00145_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 08:19:46
            Original ID  :: gnl|Prokka|HMJEJMDP_145
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 7214
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..516
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M22"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg145_1"
                     /sec_met_domain="Peptidase_M22 (E-value: 2.9e-11, bitscore:
                     32.6, seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="AMLERMMEKGVNTPYTSSAGRLFDAVASLLGICDVSSHQAEAPVL
                     LEQAAMGERNAYAYPVSAEGEEISFYSLFEALLHDKTNEVPVSLISARFHTTLASLFVQ
                     KARLLIKRTKATQVVISGGCFQNKLLTESMRRQFIMAGVPVYIPSRIPCNDGGIAVGQL
                     TIASVTPF"
     protocluster    1..7214
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1737:7214]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_unknown"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1738..7214
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_unknown"
                     /protocluster_number="1"
     cand_cluster    1..7214
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /kind="single"
                     /product="OD_unknown"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..7214
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="OD_unknown"
                     /region_number="1"
                     /rules="(minimum(1, [PFOR_II, POR, POR_N]) and minimum(2,
                     [CoA_binding, CoA_binding_2, Ligase_CoA, PTAC,
                     Succ_CoA_lig]) and not (Gly_radical_scatole or Gly_radical
                     or Gly_430_pcre or Gly_8-9_TMA))"
                     /tool="gutsmash"
     CDS             529..876
                     /locus_tag="ctg145_2"
                     /transl_table=11
                     /translation="MHELSIARSIVELVEEQADNRGASVVEELELEIGHLSGVEIQTLE
                     FALDSAIKGSKLEKARIIRHYIEGEGQCSDCETIFPMNALFSPCPHCGSYLVKILKGKE
                     LRVKSIVIKKE"
     CDS             906..1658
                     /locus_tag="ctg145_3"
                     /transl_table=11
                     /translation="MCGTCGCGEHHHHHDHTHEHSHGHEHHHHPDEGIVINLEQDILQR
                     NNLLAERNRGYFEAKNLFCLNLMSSPGSGKTTLLEETIRRLKAKRPIYVIEGDQQTSND
                     ADRIAALEIPVFQVNTGTGCHLEADMVNHAVKHLNPKEGAILFIENVGNLVCPAMFDLG
                     ESKKVVIVSTTEGDDKPLKYPHIFQEADICVINKIDLAPYLNTKVEVLRENALKVNHHL
                     QIFEVSATKGDGMDAWCDWLQTESAKCK"
     CDS             1738..3798
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_unknown: Succ_CoA_lig"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_unknown: CoA_binding_2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_4"
                     /sec_met_domain="Succ_CoA_lig (E-value: 3.5e-37, bitscore:
                     116.4, seeds: 149, tool: rule-based-clusters)"
                     /sec_met_domain="CoA_binding_2 (E-value: 3.1e-22, bitscore:
                     68.5, seeds: 225, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINRELINPQSIVVVGGSNNVHKPGGRIVRNLLDGKYKGELCVVN
                     AKETDVQGVKSYPSVHDIPETELAIISIPSKSCPEVMEVLARQKGVKAFIVISAGFGEE
                     THEGGILEQQMLDVVNEAGASLIGPNCIGLMNMNYHGVFTQPIPEFHPDGVDFISSSGG
                     TALFIIESALTKGLRFSSVWSVGNSKQNGVEDILEYMDRNFDPVLDSKIKMLYIEQIKQ
                     PDKLLYHASSLIRKGCKIAAIKAGSTESGKRAASSHTGAIASSDSAVEALFRKAGIVRC
                     FSREELTTVASIFTLKDVKGKNCAIVTHAGGPAVMLADALSKGRLNVPSLEGPIADELK
                     SKLYPGAAVGNPIDIIGTGTPEHLATAIDFCENRFDNVDLMMVIFGSPGLVKLYDTYEV
                     LHKKMEECKKPIFPILPSIVTAGPEVKSFVKKGHVNFSDEVTLGTALSRVINTPKPMST
                     DIQLYGVDVPEVRRIIDRLPGSGYLNPEEVRTLLRAANIPLVEEYASDDRDALLAFAKK
                     VKYPVVAKVVGPVHKSDIGGVALNIRGEEHLLFEYERMMRLPGVTGIMVQPMLKGQELF
                     LGAKYEDRFGHVVLCGLGGIFVEVLKDVSYGLAPLSYDETYSMIRSLRGYPIIKGTRGQ
                     KGIDEQQYADIIVRLSTLLRFASEIKEMDINPLVATDRGLFAVDARIRIEK"
     CDS             complement(3887..4501)
                     /locus_tag="ctg145_5"
                     /transl_table=11
                     /translation="MTIAFIRTYNNKQNSEVQEAVIREFAESQKIEIGKWAKEVGNSPR
                     ANRRLESIVKSLSPKDEILVSDISRVSRKMIEIIHIILLCIERKVTLRSVSDGYVFEDN
                     IDSKTLAFTFGLVSEIERKLVSIRTKEALALIRSKGVVLGRPKGSQQMGRLEPYKEQIE
                     KDLKDPSLTYAQIAEKYNVSLSSFKRFLKEYLPDKKKKKKK"
     CDS             4571..4753
                     /locus_tag="ctg145_6"
                     /transl_table=11
                     /translation="MKHFNSVGLKTKKPTNKFISWLFAEAGGFEPPVPLRVRQFSKLVV
                     SATHPHFLVCSVLLP"
     CDS             4867..5916
                     /locus_tag="ctg145_7"
                     /transl_table=11
                     /translation="MDLNKQILSRRPIVIALIAILVVLIGGGGFWVYRLAWAPNFKPDK
                     TVYVYIDDKKDFDDLCRQLRDSANCLRIGSFKQLSGLLKYPASMRTGRYAVKPGMSNLT
                     LLNDLRRGHQVAARVTFNNVRFKEDLAERISDQLMFGKENLLCLLNDSVYCDSLGFTPE
                     TINALFIPNTYEIYWNISADKFIRRMKREYDAFWTPERLKKAEEIGLTPVEASILASIV
                     EEETAASDEYPIVAGLYINRLHAGIPLQADPTVKFAVGDFSLQRILFEHLEIDSPYNTY
                     KHAGLPPGPLRIPTIKGLNSVLNHTKHKYLYMCAKEDFSGRHNFAVTLAEHNRNANRYR
                     AELNRRRIR"
     CDS             6021..7214
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_unknown: POR_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_8"
                     /sec_met_domain="POR_N (E-value: 5.9e-15, bitscore: 44.7,
                     seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKHLFLGDEAIAQAAIDAGISGVYAYPGTPSTEITEYIQGSPVT
                     KERGIHCRWSANEKTAMEAALGMCYAGKRALCCMKHVGLNVAADCFMNAAMSGINGGMI
                     ILTADDPSMHSSQNEQDNRVYGNFAMIPMFEPSSQQEAYDMVYHGFELSEKLGYPILLR
                     VTTRMAHSRAGVVTSPLKPENRMNCPEDGRQRFILLPALARKRFKSLLASQEAFTEASE
                     NSAYNKYFDAPNKDLGIITTGIAFNYLSENYPDGFEHPVLKISQYPLPRKQVEKIVGEC
                     KEILVLEEGYPVVEEQLKGFLAKGVTVHGRLDGTLQRDGELTPDAVGKALGKEIQSYYA
                     IPEVVEQRPPALCQGCGHRDMYEALNEVIAEYNGTAKVFGDIGCYTLGALPPFRAIDS"
ORIGIN
        1 gctatgcttg aacgaatgat ggagaaaggt gtgaatacac cctatacatc cagcgctggc
       61 cggctgtttg atgcggtagc ttctttattg gggatttgcg atgtctccag ccaccaagcg
      121 gaggctccgg tcttattgga gcaggcggcg atgggagaga ggaacgctta tgcgtatcca
      181 gtctcggcgg agggagagga aatctctttt tattctttgt ttgaggcatt attgcatgat
      241 aagacgaacg aggtcccggt gagcttgata tccgcccgtt tccatacgac attggcttcc
      301 ttgtttgtgc agaaagcccg cttgttgatt aaacggacga aagcgacaca agtggttatc
      361 tcgggaggat gtttccagaa taaattattg acggagtcga tgaggagaca gttcatcatg
      421 gctggggtcc ccgtctatat tccgtctcgt ataccttgta acgatggggg gatagccgtg
      481 gggcaattaa cgatcgcctc ggtgactccc ttttaaaaga gatcagatat gcatgagttg
      541 tctatagccc gtagcatcgt ggagctggtc gaggaacaag cggataaccg gggagcctcg
      601 gtggtcgaag agttggagtt agagatagga catttgtccg gcgtagagat ccaaacctta
      661 gagttcgcat tggatagcgc cataaaaggt agcaagctgg aaaaggcccg gattatccgt
      721 cattatattg agggggaagg acagtgtagc gactgtgaga ccattttccc aatgaacgcc
      781 ttgttttccc cttgtcccca ttgtggctcc tatttagtta aaatccttaa agggaaggaa
      841 cttcgggtga agtcgattgt tattaaaaag gaatgatata ttaatgaaat aaaaacttaa
      901 atactatgtg cggaacttgc ggatgcggag agcatcatca ccatcacgat catacgcatg
      961 agcattctca tggccatgaa catcatcacc atcctgatga agggatcgta atcaatctgg
     1021 aacaagatat acttcaacgt aacaacttat tggcggagcg aaaccgggga tatttcgagg
     1081 ctaagaacct gttctgcctg aacttgatga gttcgcccgg atccggtaag acaaccttgc
     1141 tggaagagac gatccgccgt ttgaaagcga agcgaccgat ctatgtgata gaaggcgatc
     1201 aacaaacctc aaacgatgcc gaccgtatag cggcgttgga gattcccgtg tttcaggtaa
     1261 ataccggtac cggctgtcat ttggaagccg acatggtcaa tcatgccgtt aagcatctga
     1321 atccgaagga gggagcgatc ctttttatag agaatgtcgg caatctggtc tgtccggcca
     1381 tgttcgatct cggagagtcc aagaaagtcg ttatcgtgag tacgacggag ggagatgata
     1441 aaccgttgaa atacccacat atctttcagg aggcagatat ctgcgtaatc aacaagattg
     1501 atctggctcc ttatctgaat acaaaagtgg aagtgcttcg ggaaaacgcc ttgaaggtaa
     1561 atcaccatct ccagatattc gaggtatccg ccacgaaagg agacgggatg gatgcatggt
     1621 gtgactggtt gcagacagag agtgcaaagt gtaaataaat accccgggtt ttaatgaata
     1681 aatggagaaa aaaactatat ttgctcccat tcattgaatc taactaatca aaatgttatg
     1741 attaaccgag aattgattaa tcctcaaagc atcgtagtgg tgggaggttc caacaacgta
     1801 cataaaccgg gcggtcgtat cgtgcgaaac ctgttggatg gaaaatataa aggagaatta
     1861 tgtgtggtaa acgccaagga gacagacgtg caaggcgtca agtcttatcc ttctgtacat
     1921 gatatcccgg agacggagtt ggcgatcatc tcgattccga gtaaatcgtg ccccgaggtg
     1981 atggaagtgc tggcccggca aaagggggta aaagctttta tcgtgatctc ggccggcttc
     2041 ggcgaggaga cacacgaggg cggtatcttg gaacaacaga tgctggatgt cgtgaatgag
     2101 gcgggagcct ccttgatcgg cccgaactgt atcgggttga tgaatatgaa ttatcatggc
     2161 gtgtttacgc aaccgatacc agaattccat cccgatggcg tggatttcat ctctagctcc
     2221 ggcggtacgg ccttgttcat tatcgagtcg gcgctgacaa aagggctgcg tttctcttct
     2281 gtttggtcgg ttgggaactc caagcagaat ggagtagagg atatccttga atatatggat
     2341 cggaactttg atccggtatt ggattccaag atcaagatgt tgtatatcga gcaaatcaag
     2401 caaccggata aattgttgta tcatgcgtct tccttgatac gtaagggatg caagatcgcc
     2461 gctatcaagg cgggaagtac ggagtcggga aagcgagctg cctcttcgca tacgggcgct
     2521 atcgctagtt cggactctgc cgtggaggct ttgttccgta aggcgggtat cgtgcgttgt
     2581 tttagccgtg aggaattgac taccgtggcg agtatcttca ccttgaaaga cgtgaaaggg
     2641 aagaattgtg cgatcgtgac acatgccgga gggcctgcgg taatgctggc ggacgcttta
     2701 tccaaggggc gtttgaatgt tcctagtttg gaaggcccta tcgctgatga gttgaaatcc
     2761 aagctgtatc cgggtgccgc tgtcggtaat ccgattgata ttatcggtac ggggacaccg
     2821 gaacatctgg ctacagccat cgatttctgt gagaatcgtt tcgataatgt ggatttgatg
     2881 atggtcatct tcggtagtcc cggtttggta aaactttatg atacctacga ggtgcttcat
     2941 aaaaagatgg aagagtgtaa gaagccgatc ttcccgatat taccgtctat cgtgacggcc
     3001 ggaccggagg tgaagagctt tgtcaagaaa ggccatgtga acttctcgga cgaggtgaca
     3061 ttgggtaccg ccctttcacg ggtgatcaat acgccgaaac cgatgagcac ggatatccag
     3121 ctatatggcg tggatgtacc ggaagttcgt cgtatcatag accggttgcc gggtagcggt
     3181 tatttaaatc cggaggaagt gcgtacattg ttgcgtgccg ctaatatccc gttagtggag
     3241 gaatatgctt cggatgatag ggatgcgttg ctggcttttg ccaagaaggt gaaatatccg
     3301 gtggtagcca aggttgtggg gcctgtgcat aagagcgata tcggtggtgt ggccttgaat
     3361 atccgtggag aagagcattt attgttcgag tatgaacgta tgatgcgtct gccgggtgtt
     3421 acgggcatca tggtacagcc gatgttgaaa ggacaggaat tattcttggg agctaaatat
     3481 gaggatcgtt tcggccatgt ggtactttgc gggttgggtg gaatcttcgt ggaggtattg
     3541 aaggatgtgt cttatggttt ggcaccgtta tcatatgatg agacttattc aatgattcgt
     3601 tccttgagag ggtatccgat cattaaaggt acgcgtgggc aaaagggcat cgacgagcaa
     3661 caatatgcgg acattatcgt tcgcctctct accttattgc gttttgccag cgagataaag
     3721 gaaatggata taaatccgtt ggtggctacg gatagaggct tgttcgctgt agacgcccgt
     3781 atccgtatag agaaataata atgattcaat gtgccaatat gcgaatatgc taatatctga
     3841 attatccact tctggtattt cattggcata ttggcacatt gaatcattat ttcttcttct
     3901 tctttttctt atcgggaaga tactctttca gaaagcgttt gaagctactt agcgatacat
     3961 tgtatttctc cgctatctgg gcgtaagtca agctcgggtc tttcaagtct ttctcgattt
     4021 gttccttata aggctccaag cgtcccattt gttgactacc tttcggacgg cccagcacca
     4081 cacctttact tctgatcaag gcaagggctt ccttcgtacg gatagagacc agctttcgct
     4141 cgatctcgga gaccagaccg aaggtaaagg ccaaagtctt actgtcgata ttatcctcga
     4201 acacatatcc gtcgcttacg ctacgaagcg ttacctttcg ctctatacaa agcaaaatga
     4261 tatggatgat ctcgatcatc ttacggctca cacgggatat atcggacaca agtatctcat
     4321 ccttgggact taaagatttg acaatacttt ccagtctgcg gttcgcacga ggactatttc
     4381 ccacctcttt agcccacttc ccgatctcta tcttctgaga ttcggcaaat tcccggatca
     4441 cagcttcttg gacctcggag ttttgcttat tattatatgt tcggataaaa gcaattgtca
     4501 taatgtatat atttaattat ctccttttaa taacagatcg acttacgata agttcaaata
     4561 tgacaaatat atgaaacact ttaattcggt tggcttaaaa acaaaaaaac caactaataa
     4621 atttattagt tggctgtttg cggaagcggg gggattcgaa cccccggtac ccttacgagt
     4681 acgtcagttt agcaaactgg tggtttcagc cactcaccca cacttccttg tgtgttctgt
     4741 gcttcttcct tagaattgcg atgcaaaggt agaactataa ttttaaataa acaaggcttt
     4801 gcacatcatt tttttcgaaa aaagatacta cttttgtgcc ttattctgat attcaataga
     4861 ttattcatgg atttgaacaa acaaatttta tcgaggcgtc cgatagttat cgccttgata
     4921 gcgattctcg ttgttttgat aggcggtgga ggcttttggg tgtaccgttt ggcttgggct
     4981 ccgaatttta agccggataa gacggtctat gtctatatag atgataaaaa ggattttgat
     5041 gatctttgcc ggcagttgag ggattcggcg aactgtctcc gtatcggtag ctttaagcaa
     5101 ttgagtggat tgttgaagta tcctgcgtcc atgcgtaccg gtcgatacgc cgtgaagccc
     5161 ggcatgagta atttaacctt attgaatgac ttgcggagag gacatcaagt agcggcccgg
     5221 gttactttta ataatgtccg tttcaaggaa gatttggcgg aacgtataag tgatcaattg
     5281 atgttcggga aggaaaatct cctgtgttta ttgaatgatt ctgtgtattg cgactcttta
     5341 ggttttaccc cggaaacgat caatgccctc ttcattccta atacctatga gatttattgg
     5401 aatatatccg cggataaatt tatacgtcgc atgaagcgtg aatatgacgc tttctggaca
     5461 ccggaacgat tgaaaaaggc agaggagatc gggcttactc cagttgaggc atctatcttg
     5521 gcttctatcg tagaagagga gacggcggca tcggacgaat atccaatcgt ggcggggctt
     5581 tatatcaacc gccttcatgc cggtattcct ttacaggcag atcctaccgt aaagttcgcg
     5641 gtgggggatt tttctttgca acgtatctta tttgagcatt tggaaataga ttctccctat
     5701 aatacctata aacatgcggg cctgcctccc ggtcctctac ggattcctac tatcaagggc
     5761 ttgaatagcg tattgaatca tacgaaacat aaatacttat acatgtgcgc taaggaggat
     5821 ttctcgggac ggcataattt cgccgtgacg ttggcggagc ataaccgcaa tgccaaccgg
     5881 tatcgggcgg agttgaatag gcgccggata cggtaatgga tctagtataa atcataagtc
     5941 tctcattcta aattgaacat ttttcattac ctttggcggc taaatagtgt gaatagtcaa
     6001 tattaagaaa acagatacac atggaaaaac atttattttt gggggacgag gccatagcgc
     6061 aagccgctat agacgctgga atctccgggg tatacgcata cccgggaacc ccttctactg
     6121 aaatcacaga atatatccaa ggttctccgg taacgaagga aagaggtatc cattgtcgct
     6181 ggagcgcgaa tgagaaaacc gccatggaag ccgctttggg tatgtgctat gccggtaaac
     6241 gtgcgctttg ctgcatgaag cacgtgggtt tgaatgtagc cgccgattgc tttatgaacg
     6301 ccgctatgag cggtatcaac ggaggtatga tcatccttac ggccgacgac ccatccatgc
     6361 actcttccca gaatgagcaa gacaaccgtg tttatggcaa tttcgccatg atcccgatgt
     6421 ttgagccatc cagccagcaa gaggcttatg atatggtata tcatggattc gagttatccg
     6481 agaaattagg gtatcctatc ttgctgcgtg taacgacccg tatggcgcat tctcgtgccg
     6541 gtgtcgtaac cagcccgttg aagccggaga accggatgaa ttgtccggaa gacggtcgtc
     6601 aacgttttat cttactcccg gcattggccc gtaaacgttt caagagtttg ctggcgtctc
     6661 aagaggcttt cacggaagct tccgagaatt ccgcatataa taagtatttc gatgccccga
     6721 ataaagactt gggtatcatc acgacgggta tcgctttcaa ttatctttcc gagaattatc
     6781 cggacggttt cgagcatccc gtattgaaga tctcccagta tccgcttccg agaaagcaag
     6841 tggagaagat cgttggcgag tgtaaggaga tcttggtgtt ggaagaggga tatccggtcg
     6901 ttgaagagca attaaaaggt ttcttggcga aaggcgtgac ggttcatggc cgtctggacg
     6961 gtacgcttca gcgtgacggc gagcttacgc cagatgcggt aggcaaagcc ttgggtaagg
     7021 agatccagag ctattacgcg atccccgagg tggttgagca acgtccgccc gcattgtgcc
     7081 aaggttgtgg acaccgggat atgtatgagg ccttgaacga ggtgatcgcc gagtataacg
     7141 gtacggctaa ggtgtttggc gatatcggct gttatacctt gggagctttg cctcctttcc
     7201 gtgcgatcga ttct
//
