LOCUS       c00262_gnlPro..         4687 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HMJEJMDP_262.
ACCESSION   c00262_gnlPro..
VERSION     c00262_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 08:19:46
            Original ID  :: gnl|Prokka|HMJEJMDP_262
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4687
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4687
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:3920]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..3920
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..4687
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4687
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             2..1747
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg262_1"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.9e-51, bitscore:
                     161.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="NSRRLINTKYYILEMEKQKITGSEALLKALIAEGVDTIFGYPGGQ
                     AIPIYDSLYDYRDQLRHVLVRHEQGATHAAQGYARVSGKVGVTLVTSGPGATNTITGIA
                     DALMDSTPMVVIAGQVPSPLLGTDAFQEVDVIGITQPITKWAYQIRKPEEIAWAVSRAF
                     YIASTGRPGPVVLDLAKDAQVGLVDYEYKKVDYVRSYQPEPDIKKDRIKAAADLINEAK
                     KPFCLVGQGVLLGGAEEELRAFLQKNDIPAGSTVLGLSALPTDFPLNKGMLGMHGNVGP
                     NRKTNECDVLIAIGMRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVPVDVKVLGNAK
                     HTIPMITALLEERKRPEWNAEFDRDEKEEYDKVIEKELYPTEGQLKMGEVVRKVSEATG
                     NDAVLVTDVGQNQMMGVRYFKYKQTRSVVTSGGLGTMGFGLPAAMGAKFGAPDRTVCFF
                     TGDGGMQMTIQELGTIMQEKLNVKIIILNNNFLGMVRQWQELFFHERYSNTIMENPDFV
                     AIAKAYGIAGRAVEKREELDDAIAEMLNHDGAYVLVANVETCGMVYPMVPAGGSVTNMI
                     MGDEK"
     CDS             1763..2317
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg262_2"
                     /sec_met_domain="ALS_ss_C (E-value: 1.8e-17, bitscore:
                     52.4, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKKLYTVIIFSENIVGLLNQITIIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDMIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEGLIRKYNARILEMNEACVVLEKSGHYDETQALFNELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLADMERKLHEKQQ"
     CDS             2324..3049
                     /locus_tag="ctg262_3"
                     /transl_table=11
                     /translation="MEKVGLFHFVAEPYLMDFRGRVTLPMIGNYLIHAASSHAGERGFG
                     FNDMSERHTAWVLSRLAIEMKEYPTAFDKINLYTWIDEVGRLFTSRCFELADENGKTFG
                     FARSIWAAIDVETRRPTLLDIEALGKYIDERPCPIEKPGKIMPAENKAEGIPYSIKYSD
                     LDINGHFNSVKYIEHLLDLFDIDQFKTREIGRLEIAYQSEGKQGMPLTLHKAESAPDKQ
                     DMAICHEGKAICRAAVTWR"
     CDS             3099..3920
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg262_4"
                     /sec_met_domain="IlvN (E-value: 6e-48, bitscore: 151.5,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 2.2e-17, bitscore: 52.6,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQMNFGGVVENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRQGKTYDKAVEDGWVPGETLFGIEEACDKATIIMCLLSDAAVMS
                     VWPTMKPYLTAGKALYFSHGFAITWNDRTGVVPPADIDVIMVAPKGSGTSLRSMFLEGR
                     GLNSSFAIYQDATGKAMDRTLALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSXXXXWVRSTTQSSRLSRNCTQT"
     CDS             3863..4069
                     /locus_tag="ctg262_5"
                     /transl_table=11
                     /translation="MGPFHDAIKPVVEKLYANVKCGNEAQISIDSNSKPDYREKLEAEL
                     KALRESEMWQTAVTVRKLRPENN"
     CDS             complement(4139..4480)
                     /locus_tag="ctg262_6"
                     /transl_table=11
                     /translation="MEARPTQKQVITSSLFWESYDNVYVQGLDLFGFYQAELYANKIKS
                     ILYELDQTYPYYPECRHLATKSRMYRNIILDSHLIIYRITEERIEVLDIVHSASSMRKI
                     KKTRNIHIE"
     CDS             complement(4447..4686)
                     /locus_tag="ctg262_7"
                     /transl_table=11
                     /translation="TMTKLSNIPAKETTAKTAKTRKTKTGPAKLKWDPTKPVQFTQEEI
                     WEHIHEIEKGPFLTLDEGFKRFEAWKQDLLKSRL"
ORIGIN
        1 gaatagtaga agattaataa acaccaaata ctatatttta gagatggaga aacaaaagat
       61 aaccggttcg gaagctttgc tgaaagcgtt gattgctgaa ggagtagata ctatcttcgg
      121 ttatcccggc ggacaggcga tacctattta cgacagttta tatgattata gggaccagtt
      181 gaggcatgta ttggtgcgcc acgagcaagg cgctacccat gcggctcaag gatatgcccg
      241 tgtatccggc aaggtaggag tgacgttggt tacttccggc ccgggcgcta cgaataccat
      301 cacgggtatc gctgatgcgc tgatggatag tacgccaatg gtcgtaatcg ccggtcaagt
      361 accctcgccg ttgttgggaa ccgatgcttt tcaggaagtc gacgtgattg gcatcacgca
      421 accgatcacg aaatgggctt atcaaatccg caagccggag gagatcgcat gggctgtttc
      481 tcgtgctttt tatatcgctt ctacaggccg tccgggtcca gttgtgctgg atttagcgaa
      541 ggacgcgcaa gtagggctgg tggactatga atataagaag gtagattacg tacgtagtta
      601 tcagccggag ccggatatca aaaaggatcg tatcaaggcc gccgccgatt taatcaatga
      661 ggcgaagaaa cccttctgtc tggtcgggca gggagtattg ttaggcggtg cggaagagga
      721 attgagagcg tttctccaaa agaatgatat acctgccgga tctacggtat tgggcttatc
      781 tgcgttgcca accgatttcc cattgaacaa gggaatgctc ggtatgcatg gaaacgtagg
      841 gccgaaccgg aaaacgaatg agtgtgatgt attgatcgct atcggtatgc gtttcgacga
      901 ccgtgtgact ggcgatttaa agacatacgc taagcaagcc aagattatcc atctggatat
      961 cgacaactcg gaaatcggta agaacgtccc cgtagatgta aaggtgctgg gtaatgccaa
     1021 gcacacgata ccgatgatca cggcgttgtt ggaagaacgt aaacgtccgg aatggaatgc
     1081 cgagttcgat cgggacgaga aagaggaata cgataaggta atcgagaagg aattgtatcc
     1141 gaccgagggc caactgaaaa tgggcgaggt agtccgtaag gtttccgagg cgaccggtaa
     1201 cgacgctgta ttggtgaccg acgttgggca gaaccagatg atgggtgtcc gctatttcaa
     1261 atataaacaa acccgtagcg tggtgacttc cggaggttta ggtacgatgg gatttggtct
     1321 gccggccgct atgggcgcta agttcggggc tccggaccgt acggtctgct tctttaccgg
     1381 tgatgggggt atgcagatga cgattcagga attgggtacc atcatgcagg agaaactgaa
     1441 cgtgaagatt atcattctta ataataactt cttaggtatg gtacgtcagt ggcaagaatt
     1501 gttcttccac gagcgttatt caaacaccat catggagaat ccggatttcg tggcgatcgc
     1561 taaagcctat ggtatcgctg gccgtgccgt tgaaaagcgg gaggaattgg acgacgctat
     1621 cgccgagatg ctaaaccacg acggcgctta cgtgttggtc gctaacgtgg agacttgcgg
     1681 aatggtatat ccgatggttc ctgccggggg aagcgtgaca aacatgatta tgggagacga
     1741 gaaataagga ggagatgaag ctatgacaac aaagaaatta tataccgtta ttatcttttc
     1801 agagaatatc gtaggtcttt tgaaccagat aacgattatc tttacacgcc gacagctgaa
     1861 catcgagact ctgtccgtct ctccgtccgc tatcaagggc atccataagt ttacgatcac
     1921 gaccttcgcc gatgaggata tgatcgataa ggtggtgaaa cagatcgata aacgtgtgga
     1981 tatcttgaag gcttattata atacggatga ggatctggtt tatcaagaga tcgcccttta
     2041 taagctaagt accgagcttt tcatcaagat gggaaccgtg gagggattga tccgtaaata
     2101 caacgctcgt atcttggaga tgaacgaggc ctgcgtggtg ttggagaaga gtggccacta
     2161 tgacgagaca caagccttgt tcaatgagtt gagcgagacg atcggtgtcc tgcaattcat
     2221 ccgctccgga cgtgtggcta tcacgaagag caaggtggag cgcttgagcg atatgttggc
     2281 cgatatggag cgaaagttac atgaaaagca acaataataa gatatggaga aagtaggatt
     2341 atttcatttc gtggcggagc cgtatttgat ggatttcagg ggacgtgtaa cgctccctat
     2401 gattggtaac tatttgattc acgccgcttc cagccatgcc ggagagcgtg ggttcggttt
     2461 caatgatatg tcggagcgtc atacggcttg ggtgttgtcc cgtctggcta tcgagatgaa
     2521 ggaatatcct accgccttcg ataagattaa tctatacact tggatcgatg aggtcggacg
     2581 cctcttcacc agtcgttgtt tcgagctggc ggatgagaat gggaaaacct ttggattcgc
     2641 ccgttctatt tgggcggcta tcgacgtgga gacccgccgt cctaccttat tggatataga
     2701 ggcattgggc aaatatatcg acgagcgtcc gtgcccgatc gagaagccgg gcaagatcat
     2761 gccggcggag aataaggcgg agggaatccc gtattcgatc aaatacagcg acttggatat
     2821 caacggtcac ttcaatagcg tgaagtatat cgagcacctg ctggatttgt tcgatatcga
     2881 tcagttcaag acccgtgaga tcggccgtct ggagatcgcc taccaatccg agggtaaaca
     2941 aggtatgccg cttacgcttc ataaggcgga gtccgctccc gataagcaag acatggctat
     3001 ttgccatgag ggaaaggcga tctgtcgtgc ggcggttact tggagataat aaaagagata
     3061 cataaatagg tttttaaaca ttaatagtta aaaagaaaat ggcacaaatg aattttggcg
     3121 gtgttgtaga gaatgtaatg acccgcgagg aatttccgtt ggaaaaggca agagagatat
     3181 taaaagatga gacaatcgct gttatcggct atggcgtaca gggaccggga cagtcattga
     3241 accttcgtga caatggcttc aacgtaatcg ttggccagcg ccaaggtaag acttacgata
     3301 aagcggttga ggacggatgg gttccgggtg agactctgtt cggtatcgag gaggcttgcg
     3361 acaaggccac gatcatcatg tgcttgttgt ccgacgctgc cgtaatgtct gtatggccta
     3421 cgatgaagcc ttatttgaca gctggcaagg ccctgtattt ctctcatggt tttgcgatca
     3481 cttggaacga tcgtacgggc gttgttcctc ccgcggatat tgacgtgatc atggtcgctc
     3541 cgaaggggtc tggtacgtct ttgcgttcca tgttccttga gggtcgtggc ttgaactctt
     3601 ctttcgctat ctatcaagac gctactggca aggcgatgga tcgtacgttg gcgttgggta
     3661 tcggtatcgg ttccggctac ttgttcgaga cgactttcat ccgtgaggct acttccgatt
     3721 tgactggtga gcgtggttcc ttgatgggcg ctatccaagg tttgttgttg gcccagtatg
     3781 aggtattgcg cgagaatgga catactcctt ccgaggcttt caacgagacg gtcgaggagt
     3841 tgactcaatc ctnnnnnnnn nnatgggtcc gttccacgac gcaatcaagc cggttgtcga
     3901 gaaattgtac gcaaacgtaa aatgcggtaa cgaggctcag atctctatcg actcaaactc
     3961 taagccggat tatcgtgaga aattggaggc tgaattgaag gcattgcgcg agagcgagat
     4021 gtggcagaca gctgttactg tacgtaagct tcgtccggag aacaactaat ccaatcttaa
     4081 tccttatata tcagcaaaaa gaggcgggtc acttacgggt ggctcgcctt tctttgtgtt
     4141 attcgatgtg gatattccta gtcttcttga tctttcgcat gctggatgct gaatggacga
     4201 tgtccagcac ctcgatgcgt tcctcggtga tgcggtagat gataaggtgt gaatctagga
     4261 tgatgttccg gtacatgcgg cttttcgtgg ctaggtgtcg gcattcggga taataaggat
     4321 aggtttggtc taactcgtat aagatggatt ttatcttgtt agcgtataat tccgcttggt
     4381 agaatccaaa taagtcaagg ccttgaacat atacattatc gtaactttcc caaaataaac
     4441 tactggttat aacctgcttt tgagtaggtc ttgcttccat gcctcaaaac gtttaaaacc
     4501 ttcatctagg gttaggaacg gtcccttctc aatctcatgg atatgttccc agatctcttc
     4561 ttgggtgaat tgcaccggct tggtgggatc ccacttgagc tttgcgggtc cggtcttggt
     4621 cttacgtgtc tttgcggtct tggccgtagt ttccttggcg gggatgttgc ttaattttgt
     4681 catagtc
//
