LOCUS       c00382_gnlPro..         4393 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KIJGAGNJ_382.
ACCESSION   c00382_gnlPro..
VERSION     c00382_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 10:18:28
            Original ID  :: gnl|Prokka|KIJGAGNJ_382
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4393
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4393
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[123:4253]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      124..4253
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..4393
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4393
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             124..1959
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg382_1"
                     /sec_met_domain="ILVD_EDD (E-value: 1e-218, bitscore:
                     715.1, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMKNPLRSSYSTEGRRMAGARALWRANGMKEEQFGKPIIAIVNSF
                     TQFVPGHVHLHEIGQQVKAEIEKLGCFAAEFNTIAIDDGIAMGHDGMLYSLPSRDIIAD
                     SVEYMVNAHKADAMVCISNCDKITPGMLMASMRLNIPTIFVSGGPMEAGNLDGRALDLI
                     DAMIEAADDSISDEQVEKVERSACPTCGCCSGMFTANSMNCLNEAIGLALPGNGTVVAT
                     HANRTRLFKKAAKMIVDNAFKYYRDGDDSVLPRSIATRQAFLNAMSLDIAMGGSTNTVL
                     HLLAVAHEAEVDFTMKDIDMLSRKTPVICKVAPSCSYHVEDVNRAGGIIGIMNELVKAG
                     LVDGSVKRADGLTLNEAIDQYCITSVNVTEEAINIYKSAPAHRFNLVLGSQESYYKELD
                     TDRATGCIRDVEHAYVKDGGLAVLYGNIAQDGCVVKTAGVDESIFRFAGPAKVFDSQDA
                     ACEGILKDQVVSGDVVVITYEGPKGGPGMQEMLYPTSYIKSKHLGKECALITDGRFSGG
                     TSGLSIGHISPEAAAGGAIGLVKDGDIIEINIPERTIHVKVTDEELAKRREAEEARGTK
                     AFTPPFRQRTVSKALKAYAKMVASADKGGVRIVED"
     CDS             1986..3686
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg382_2"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.3e-51, bitscore:
                     162.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKQKITGSEALLKALIAEGVDTIFGYPGGQAIPIYDSLYDYRDQ
                     LKHILVRHEQGATHAAQGYARVSGKVGVTVVTSGPGATNTITGIADALMDSTPMVVIAG
                     QVPSPLLGTDAFQEVDVIGITQPITKWAYQIRRPEEIAWAVSRAFYIASTGRPGPVVLD
                     LAKDAQVGLVDYEYQKVDYVRSYQPEPDIREERIEAAASLINNAKKPFCLVGQGVILGG
                     AEEELKEFLLKNDIPAGSTVLGLSALPSDFPLNKGMLGMHGNVGPNRKTNECDVLIAIG
                     MRFDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVPVDVKVLGNAKHTIPMITALLEERK
                     RPEWNAEFEPDEKEEYNKVIEKELYPTEGQLKMGEVVRKVSEATDNDAILVTDVGQNQM
                     MGVRYFKYKQTRSVVTSGGLGTMGFGLPAAIGAKLGAPDRTVCFFTGDGGIQMTIQELG
                     TIMQENLNVKIIVLNNNFLGMVRQWQELFFNERYSNTIMKNPDFVAIAKAFGIASRAVD
                     KREDLDEAIAEMLNHDGAYMLVANVETCGMVYPMVPAGGSVTNMILGDK"
     CDS             3699..4253
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg382_3"
                     /sec_met_domain="ALS_ss_C (E-value: 4.5e-19, bitscore:
                     56.7, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTKQLYTVIIFSENTVGLLNQITVIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDTIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEDLIRKYNARILEMNEDCVVLEKSGHYDETQALFKELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLSAMEKKLQEKHV"
     CDS             4290..4391
                     /locus_tag="ctg382_4"
                     /transl_table=11
                     /translation="MEKNKVGEFHFVTESYLTDFRGRITIPMIGTYLL"
ORIGIN
        1 cttctagtca ttagtaggta aggagaaagg tgtgtaagaa gttgtgaagt cgtaaaagat
       61 atttcttaag cctttctcca tatagagaag ggctttttta ttgactaaaa gataaaaaca
      121 gatatgatga agaatccgtt aagaagctcc tatagcacag aaggcagacg tatggccgga
      181 gcccgtgcat tatggcgtgc caacggcatg aaagaagaac agttcggtaa accgatcatt
      241 gccattgtga attcatttac ccagtttgta ccgggccatg tgcatctaca cgagatcgga
      301 cagcaggtaa aagcggaaat cgaaaagctc ggttgctttg ccgcagaatt taatacgatc
      361 gctattgatg acggtattgc tatgggacac gacggaatgc tttattctct gccttcccgc
      421 gacatcattg ctgacagtgt ggaatatatg gtgaatgcgc ataaggctga tgcaatggtt
      481 tgtatcagta actgcgacaa gattactccg ggtatgctga tggccagtat gcgtctgaat
      541 attccgacaa tctttgtatc cggcggtccg atggaagccg gtaatctgga cggacgtgca
      601 ctcgatttga tcgacgccat gattgaagcg gctgacgatt ctatcagcga tgaacaagta
      661 gaaaaggtgg aacgttccgc ttgcccgacc tgcggttgct gttctggtat gttcacggct
      721 aactctatga actgtctgaa cgaagcgatt ggattggctc ttcccggcaa cggaacagtt
      781 gttgcaacac atgccaaccg tacccgcctg ttcaaaaaag ccgcgaagat gattgttgat
      841 aatgccttta aatattatcg tgacggcgat gattccgtat tgcctcgcag tattgccacc
      901 cgtcaggcct ttctgaatgc tatgtcgctg gatattgcca tggggggatc gacgaataca
      961 gtccttcacc tgttggccgt ggctcatgaa gcggaagtcg attttacaat gaaagacatc
     1021 gatatgcttt cacgcaaaac accggttatc tgtaaagtgg ctccgagttg ttcttatcat
     1081 gtggaagatg tgaaccgtgc cggaggtatt atcggtatta tgaatgagct ggtaaaagcc
     1141 ggtctggtgg acggttccgt gaaacgtgcg gatggtctga ctttgaatga ggctatcgac
     1201 caatactgca ttacctctgt aaatgtaacg gaagaagcaa tcaatattta taaaagtgct
     1261 ccggcccacc gtttcaatct ggtgctcgga tcgcaggaaa gttattataa agaactggat
     1321 accgaccgtg caaccggatg tatccgcgat gtggaacatg cttatgtgaa agacggcggt
     1381 ctggctgttc tgtatggaaa tattgcacag gacggttgtg tggttaaaac agccggggta
     1441 gatgaaagta tcttccgttt tgccggccct gccaaagtat tcgattcgca ggatgccgct
     1501 tgcgaaggta tcctgaaaga tcaagtcgtc tccggcgatg tcgtcgttat cacctatgaa
     1561 ggtcctaagg gtggtccggg tatgcaggaa atgttgtatc ctacctctta tataaagagt
     1621 aaacatctgg gtaaagaatg tgcgttaatc acagacggac gcttcagcgg tggaacatcg
     1681 ggtttgtcaa tcggacatat ttctcccgaa gcggctgcag gcggagcgat tggcttagtg
     1741 aaagacggcg atattatcga aattaatatt cccgaaagaa ccatacatgt aaaggtgaca
     1801 gacgaagaac tggccaaacg ccgtgaagcg gaagaagccc gcggaacaaa agcctttaca
     1861 cctcctttcc gccaacgtac ggtatcgaaa gcactgaaag catatgcaaa gatggttgct
     1921 tcggccgata agggcggtgt acgaatagta gaagattaat aaacaccaaa tactatattt
     1981 tagagatgga caaacaaaag ataaccggtt cggaagcttt gctgaaagcg ctgatcgctg
     2041 aaggagtaga tactatcttc ggttatccgg gtgggcaggc gataccaatt tacgatagtt
     2101 tatacgatta cagagatcag ttaaaacata ttctggtgcg ccacgaacaa ggtgcaacac
     2161 atgctgcaca gggatatgcc cgtgtttccg gaaaagtggg agtaacggtg gttacttcgg
     2221 gtcccggggc aaccaatacc atcactggta ttgccgatgc gctgatggac agtacaccga
     2281 tggtggtgat tgccggccag gttccgtctc cgctgcttgg aacagatgct ttccaggaag
     2341 ttgatgtgat cggtatcaca caaccgatta ccaaatgggc ttaccagata cgccgcccgg
     2401 aagaaattgc ttgggccgtt tcccgtgctt tctatatcgc atcgaccggt cgcccgggac
     2461 ctgtggtact ggatttggcg aaagatgcac aggtgggttt ggtagattat gagtatcaga
     2521 aagtggatta tgttcgtagt taccaacctg aaccggatat cagggaggaa cgtatcgagg
     2581 cggctgcttc attgataaat aatgccaaaa agccattctg tctggtaggg cagggggtta
     2641 tcctgggagg agctgaagaa gaactgaaag aattcttgtt gaaaaacgat ataccagccg
     2701 gttctaccgt attgggcttg tctgcattac cttcggactt cccattaaat aaaggtatgt
     2761 tggggatgca tggaaatgtc ggaccgaacc gcaagacaaa cgaatgtgac gtgctgattg
     2821 ctatcggtat gcgtttcgat gatcgcgtaa ccggcgacct gaagacttat gccaagcagg
     2881 caaagattat ccacctggat atcgacaatt cggagatcgg aaagaatgtg ccggtcgacg
     2941 tgaaagtgct gggaaatgcc aagcatacga ttccgatgat tacggcttta ctggaagaac
     3001 ggaagcgtcc ggaatggaat gctgaattcg aaccggatga aaaagaggaa tataataagg
     3061 taatagaaaa agaactctat cctaccgaag gccaactgaa aatgggcgaa gtagtccgta
     3121 aggtttccga agcaaccgat aatgatgcga ttctggttac ggatgtaggt cagaaccaga
     3181 tgatgggtgt tcgctatttc aaatataaac aaacacgcag cgtagttact tcaggaggtt
     3241 tgggaacgat gggctttggc cttcccgccg ccattggagc gaagctggga gcgcctgacc
     3301 gtacggtctg tttctttacc ggcgacggtg gtatccagat gactatccag gagttgggaa
     3361 ctatcatgca ggaaaatctg aatgtaaaga tcatcgttct taacaacaat ttcctgggaa
     3421 tggtacgcca gtggcaggag ctgttcttca acgaacggta ttcgaatacc atcatgaaga
     3481 atccggattt tgtagcgata gccaaggctt ttggtattgc ttcccgtgcg gtagataaac
     3541 gggaagactt ggatgaggcg attgctgaaa tgttgaatca cgatggtgcc tatatgttgg
     3601 ttgccaatgt ggaaacttgt ggtatggtat atccgatggt tccggccgga ggaagcgtga
     3661 caaacatgat tttgggtgat aagtaaggag gagaaactat gaatacaaaa caattatata
     3721 ccgttattat cttttcggaa aacactgttg gtcttctgaa tcagataact gttatcttta
     3781 cgcgccggca actgaacatt gagacgcttt ctgtttctcc ctctgctata aagggaatac
     3841 ataagtttac aattactacc tttgccgacg aggatacgat cgacaaggtc gtaaaacaga
     3901 tcgacaagcg tgtggatatc ctgaaagcct attataatac ggatgaagac ctggtttacc
     3961 aggaaatcgc tctttataaa ctgagtaccg aactctttat caagatgggg acggttgagg
     4021 atctgatccg taagtacaat gcccgtatcc ttgaaatgaa tgaggattgt gtggtgttgg
     4081 aaaagagtgg tcattatgat gagacacagg ctttgtttaa agaattgagt gagacgatcg
     4141 gtgtcctgca atttatccgt tccggacgcg ttgctataac gaagagtaag gtagaacgtc
     4201 tgagcgacat gttatctgca atggaaaaga agttgcagga aaaacatgtc tgagaataat
     4261 aaggaaacat tttgtaaata aagtaaatta tggagaagaa caaagtagga gaatttcatt
     4321 tcgtaacaga gtcttatctg acggacttcc ggggacgtat tacaatccct atgatcggaa
     4381 cttatttgtt gca
//
