LOCUS       c00007_gnlPro..        14755 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ALJCPKDN_7.
ACCESSION   c00007_gnlPro..
VERSION     c00007_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 08:20:50
            Original ID  :: gnl|Prokka|ALJCPKDN_7
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14755
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14755
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[276:4755]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      277..4755
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
     cand_cluster    1..14755
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /kind="single"
                     /product="Glycine_cleavage"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14755
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Glycine_cleavage"
                     /region_number="1"
                     /rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T, GDC-P,
                     SoxG]) and GCV_H and GCV_T_C)"
                     /tool="gutsmash"
     CDS             complement(277..3123)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GDC-P"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Beta_elim_lyase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_1"
                     /sec_met_domain="Beta_elim_lyase (E-value: 3.2e-09,
                     bitscore: 30.0, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="GDC-P (E-value: 1.4e-178, bitscore: 587.6,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTHSDFASRHIGPQGEERREMLDSLGYRTLDELIADIVPADIRM
                     KAPLDLPAAKSETEALEELRSILRKNKLLKTFIGQGYYGTITPSVILRNVLENPGWYTA
                     YTPYQPEIAQGRLEMLMNFQTMVSSLTGLPVANASLLDEGTAAAEAVTMCRNARPKANT
                     FFVADTCHPQTISVIRTRAAFQGVNIIVGDCSSFDPASIGADLAGVLVQYPDTLGRICD
                     YTDFFSRVHATGALCVVAADLMALTIIREPGAFGADICIGNTQRFGIPMGFGGPHAAYM
                     SCTDALKRRMPGRLIGMSIDTLGRPAYRLALQTREQHIRRDKATSNICTAQVLLAVLAA
                     FYAVYHGQEGLKRIGTEIHLKTKSLYKALTEAGIAIENKNFFDTLLLSVPGQADAMVQK
                     ALEAGYNIRRVDADHAAISLDETATCADIAALASALAGAETSATCDCDAPAWDPVHTRQ
                     TPFCTEKAFNSYHSETEMMRYIRRLESRDLALNEAMIPLGSCTMKLNAASEMIPITWPE
                     ANSLHPFVPADQSEGIREMLSVLSDRLAKITGFAAVSLQPNAGAAGEYAGLLAIRRYQK
                     HAGEGHRNVCLIPTSAHGTNPASSAMAGLKVVPVKCDERGNIDMVDLKSQAEAHKDNLS
                     CIMVTYPSTHGVYEQTIKELCDIVHANGGQVYMDGANMNAQVGLTCPGCIGADVCHLNL
                     HKTFAMPHGGGGPGIGPIGVAEHLVPFLPGHLTLGHEEGAVASAAWGSASIAAICWMYL
                     SMMGPDGLREATEMAILNANYIAKKLGHLFPVLYSGNKGLVAHECILDPRQLTHDAGLT
                     VDDIAKRLMDYGFHGPTMSFPVPGTLMVEPTESEPKKELDRFIEAMERIHAEITAIING
                     TADKEDNVLKNSPHTAEMVSADEWRHPYSRSEAAYPVSGLLIHKFWPYVGRVDNVYGDR
                     NLVCTCDTVEEFSKAVEL"
     CDS             complement(3219..3599)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_H"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_2"
                     /sec_met_domain="GCV_H (E-value: 3.1e-47, bitscore: 153.0,
                     seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDVPENLLYSKDHEWIEIDGDIGTIGISDHAQAELSDVVFVDLP
                     EVGATVAAGDPVAVVESVKAASDVYTPVSGEILEVNEELSNDPSLINSDPYGAGWLYKI
                     RLDVPTETEDMMNATDYEEYCS"
     CDS             complement(3670..4755)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_3"
                     /sec_met_domain="GCV_T (E-value: 7.4e-87, bitscore: 284.4,
                     seeds: 72, tool: rule-based-clusters)"
                     /sec_met_domain="GCV_T_C (E-value: 6.2e-23, bitscore: 74.1,
                     seeds: 348, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTDVKSTPLATKHVELGARMVPFAGWNMPVQYTGILDEHKAVR
                     ETCGIFDISHMGQFTVAGGSAAAWLNSMLTNDINKLNVGQGQYSVMLNDRAGVIDDLIL
                     YRMEPETFFVVVNASKIDEDFAWLSAHQPAGVTLENHSDEYVGLAVQGPECGEVFSRVI
                     PGVELPPRNGISRITAEGTDLIICRTGYTGEDGFEFFCPAKEGVKWFEAFLGAGAKPCG
                     LGARDSLRLEMCYPLNGSDLSPDKTPLEAGLGFFCALDTDFIGSDILREQKANGLSRRL
                     AAIEYTGKGAPPRAHYAVHVPGGEAIGELTSGVLSPSLMKGIALAYLPAAYAKVGTELE
                     IDVRGRKFPAVVVKKPFYKKG"
     CDS             complement(4831..5952)
                     /locus_tag="ctg7_4"
                     /transl_table=11
                     /translation="MLQAGIVGLPNVGKSTLFNAVTRTRKAQAANYPFCTIDPNVGMVT
                     VPDPRLQVLSDMSGSEKIIPTLIEFVDIAGLVKGASEGAGLGNQFLANIREVDAIVQVV
                     RCFDNDDIIHELGSVDPLRDIDIINSELILADIATMEKRLSSRERKARSGDKEAKAEVA
                     LITKLLPHLNEGNPALTLEPQLDDDERKLLHSFQLLSDKKSIFACNVNEDELADAISNP
                     DAHPYVSQVKKYVAEHHNAEAIVISARIEEELIDVSEEESREFLESLGVKDSGVSDLIR
                     AVYHLLGLRTYLTTGIKETRAWTIPAGAKAPQAAGVIHTDFERGFIAAEVVHYDDLVSC
                     GGKAGAREHGKLRIEGKEYVVKDGDVIEFRFNV"
     CDS             complement(6011..6934)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S11"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_5"
                     /sec_met_domain="Peptidase_S11 (E-value: 2e-55, bitscore:
                     181.3, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLFALLAGFSLCLSSTSCQSYGDSSDYIPLATPVPPQLSQPVSH
                     ALPRPANFPTRPVAIPSSAPRTPRCASACVMDALTGKVLFSHNGLQHRQVASTQKLVTA
                     MVVMEHGSLDKKVVIQPSDTKADPTKLGFRAGEVYSRRELLNAMMIRSFNDVALALARD
                     TAGSVPRFAQLMNAKARQMGMYNSRFANPNGLPADQYSTAIDMARCAYYVYRNPELRNI
                     ICKRQYAFTRANGRTLLLRNTNKLLTQNPWVTGMKTGYTNAAGRCLVSSAGVNGRHVIV
                     VVLGCHPSRIWTESENLIRWALGSAA"
     CDS             complement(7496..8623)
                     /locus_tag="ctg7_6"
                     /transl_table=11
                     /translation="MTPREAAIALNLIPGLGPVRIMRLLQVFASPELILESPSSLLMEI
                     PGVGAQLACRISSWRSIVNPYRELELADNAGAAVTTVFDDSYPSSLRALPDPPIVLYSW
                     GNWTGTDAERSIAVVGSRMATHYGRLCARNISHDLAEAGVTVISGLARGVDTEAHTGAM
                     DAEGRTIAVIGAGLNKLYPRENRNLAQRIADGHGAVVSEFPMDLPPSRTTFPMRNRIVS
                     GWSRATLVVEASGRSGALITARTAAEQGRDVFCIPGPVDRHSSDGCHALIRDGAILATG
                     ASDILQDMNWAVPEQGLPLFSPCPPAGASTPPLPTLEEKEILHAIRLGFNTIDTLCTSL
                     GKTAHTITPLLAKMQIAGQITPDAGGYFSINGREL"
     CDS             complement(8620..9732)
                     /locus_tag="ctg7_7"
                     /transl_table=11
                     /translation="MKIVHLVPSMESGGVEQVVMELGSGLSSRGVENIVVSGGGRLVPR
                     LEKEGSRHILMPIGKKSISTLFRIGALRALLQAVRPDILHLHSRVPAWAGYLAWKKLPP
                     EDRPGLVTSVHGFYSVNRYSAIMSRGERVIAVSNCIRDYILDHYPSTPPDHIRIIPNAI
                     SPDQYHPAYSPSREWLTGWFMSYPELKGKFTLCLPGRITRLKGHLDLIPVVRQLLEQGI
                     PAHAVIVGEAKKGKEEYKNEVLRAIERSGVSQSFTWTGHRQDLREILSTCSVTLSLTKS
                     PEAFGKSTLEALALGKPVAGYAHGGVKEQLDAFLPEGNVAVGDTAAMADLLARWHAQPP
                     PLPRQIPSPYNMQDMIQAHLDVYQELTPYS"
     CDS             complement(9729..10745)
                     /locus_tag="ctg7_8"
                     /transl_table=11
                     /translation="MNKSMPPTKNFLLSGGNWIACTPPPLHNAAYMNIRILSDGKQGHL
                     NQSLGLAQALISKAGGTVETVDLQGLSLLGKIRKVVTGSDIPRPDLFISAGHATHIPLI
                     CARHHFKTRAVLCMKPTLPCSFFDLCLIPRHDLDSGRDYTDTDIFPTQGALHPMRPDPS
                     VPKDTTLILIGGPSKDFDWDDESMLNQLASISIHTPGHLVLTTSRRTPDGFAEKIRTAV
                     PELTVVPVEETRPGWVARHLAHASAAWVSQDSVSMVYEALGSGAPVGILSVPRRHGSRK
                     SRILSGLETLEKEGMVTGYSDWKKQNFRLTAPGSPLLEADRAADYILSRFFPQLRAL"
     CDS             10755..11816
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_16"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:4Fe-4S dicluster domain (Score: 66.5; E-value:
                     1e-20)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_9"
                     /sec_met_domain="Fer4_16 (E-value: 3.1e-20, bitscore: 66.5,
                     seeds: 227, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLTPDSSVIKDSLCAVSRQLGFSGCRVARAEKSPHAEKLFQWLER
                     GWHAGMEWMARSPERRTDPAEVLPGCRSVICLSYDYDSPGRRPEGEGSICLYAHGKDYH
                     GILEEKLADLQELLSIYGGKQRGYVDSGPVMERDHAEACGLGWRGKSGLIVRRKGGSRF
                     FIATLLTTLELEPDAPVSNGCGSCRRCAALCPTGAIMENGQVDAGRCLSYWTIEHRGAI
                     PEEIRPLIGTRLYGCDTCVTVCPWNGKPLPDVDERFRMSRLLASIPLRGLLSLDAGGFA
                     ALFRNSPLKRLKREGLLRNGCVVLGNAGTPDDIDFLKALYGESPLVEEHASWAVERILR
                     RHGRHASSSGARD"
     CDS             11935..12312
                     /locus_tag="ctg7_10"
                     /transl_table=11
                     /translation="MARLFGTEIPNEKRIEASLPYIYGIGRSTSKRILEQAGINPDIRT
                     GQLTDEQLTKIVQVITTDGILIEGDLRREKQSILKRLTSINCYRGQRHRRGLPVRGQRT
                     RTNARTRKGKKKTVGAQAKKK"
     CDS             12346..12897
                     /locus_tag="ctg7_11"
                     /transl_table=11
                     /translation="MASEEITNETAEQPVEAAASAPVAETPAAAVSAPEEIKKPEPRKD
                     IFAELGLGGDDDKPKILKAKGSKNVSTGVVHVSSTFNNTVVTVTDQRGNVIGWSSAGKM
                     GFKGSRKSTAYAGQVVCQDACRQAMGHGLREVEVRVKGPGSGRESAVRAVQTIGIEITS
                     IKDVTPIPHNGCRPPKARRV"
     CDS             12933..13544
                     /locus_tag="ctg7_12"
                     /transl_table=11
                     /translation="MARYTGPRDKVSRRFGVALFGSTKALEKRPFPPGQHGMRAGRKKK
                     SDYGVMLAEKQKLRFQYGVLEGQFRKYYAEAARRRGITGDILLQLLELRLDNVVYRLGF
                     SNTRAGARQLVSHGHITVNGKKTNIASYSCRPGDVIAVGGKASSQQLVTRFLDLTQATV
                     VPDWLECDRDKLTGKIARVPSKEEIAPIVNEQLIVEFYSR"
     CDS             13675..14442
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_13"
                     /sec_met_domain="HAD (E-value: 1.5e-35, bitscore: 116.8,
                     seeds: 107, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDDWKKRGAALFDMDGTLLPWDTQYVFSCFVVRRHPWRRLLIFL
                     FLACIPLYILRIWDENRMKRAYLMYLWGLPAETVREYGRKFAEMAQEWIYPELKERLAG
                     YRKKGYLCLMVSASPSFYVKPLGELLGFDEVLGTDVLLEERMPAMPELPNGNNKGAVKV
                     ERLRERNVLPEHGVLENAVAYSDSAADLPMLLSCRRRVLVNPSPALKEDRLLDGAECLY
                     PARPWKGRFGKIWRIGFFVMGLVNVNNVKSMIC"
ORIGIN
        1 aagggcagag aaaaagctca tctgagacgt agctcaacgg atttctaatc cgaagtcaac
       61 actctatttt gagtacaaat gggtcatcaa aatgaaaggg gaggaaaagc agggtaggag
      121 aaatgtgcct ttttcttttt taatacatac tgcttttatg cttaattgtt ttctggatgc
      181 gtttgtttct tcggattaga aatccgattc ttgaacataa gaaaaaggct gctccaaatg
      241 aatggaacag cctttttgaa aggaaggatg agatttttat aactctacgg ccttggagaa
      301 ttcctccacc gtgtcgcagg tgcagaccag attgcggtct ccgtacacat tatccacccg
      361 gcctacatac ggccagaatt tgtgaataag gagaccggag accggataag ccgcttcact
      421 gcgggagtag ggatgccgcc attcgtcggc agagaccatt tctgcggtat ggggcgagtt
      481 tttcaggacg ttgtcttcct tgtctgctgt accgttgata atggccgtga tttccgcatg
      541 aatgcgttcc atggcttcaa tgaagcggtc cagttctttt ttgggttccg attccgtcgg
      601 ctccaccatc agggtgcccg gaacggggaa ggacatggtg gggccgtgga agccgtagtc
      661 catgagcctt ttggcaatgt catccaccgt gaggccggcg tcatgagtga gctggcgcgg
      721 atccagaatg cattcatgcg ccaccagccc cttgttgccg gagtagagaa ccgggaagag
      781 atgtccgagt ttcttggcaa tgtagttggc gttaaggatg gccatttccg tggcttccct
      841 gaggccgtcc ggccccatca tggagagata catccagcag atggcggcga tggaggcgct
      901 tccccacgcc gcagacgcta cggccccttc ttcatggccc agcgtgaggt gtccgggcag
      961 gaagggtacg aggtgttccg ctacgccgat gggcccgatg ccgggaccgc cgccgccgtg
     1021 cggcatggca aaggttttat gcaggttcag gtggcagacg tccgcgccaa tgcagccggg
     1081 gcaagtcaga cctacctggg cattcatgtt ggcgccgtcc atgtacacct ggccgccatt
     1141 ggcatggacg atgtcgcaga gttccttgat tgtctgttca tataccccgt gcgtggaggg
     1201 gtacgtgacc atgatgcagg aaagattgtc cttatgggct tccgcctggg atttcaggtc
     1261 taccatgtcg atgttgcctc tttcgtcgca tttgacgggc accaccttga ggccggccat
     1321 ggcggaggag gcgggatttg ttccgtgggc ggaggtggga atgaggcaga cattgcggtg
     1381 gccttctccg gcgtgcttct ggtaacggcg gatggccagt agcccggcat attcccctgc
     1441 ggcgcccgcg ttgggctgga gggagacggc ggcaaagccg gtgattttcg ccagacggtc
     1501 ggacaggacg gagagcattt cccggatgcc ttccgactgg tccgccggaa caaagggatg
     1561 cagggagttg gcttccggcc acgtgatggg aatcatttca gaggcggcat tcagcttcat
     1621 cgtgcaggag cccagaggga tcatggcttc atttagagcc aggtcccggg attccaggcg
     1681 gcggatgtag cgcatcattt ccgtttcgga atggtaggag ttgaaagcct tttccgtgca
     1741 gaaaggcgtc tggcgcgtgt ggacgggatc ccaggcagga gcgtcgcaat cgcaggtggc
     1801 ggatgtttcc gcacctgcaa gggcggaggc cagtgccgct atatccgcac aggttgcggt
     1861 ttcatccaga gagatggctg cgtggtcggc atccaccctg cggatgttat acccggcttc
     1921 cagggctttt tgcaccatgg cgtccgcttg tccgggaacg gacagcagca gggtgtcaaa
     1981 gaagtttttg ttttcaatgg cgatgccggc ttccgtgagc gccttgtaca ggcttttggt
     2041 tttcaagtgg atttccgtgc cgatgcgttt gaggccttcc tggccgtggt atacggcgta
     2101 aaaggcggca agcacggcca ggagcacctg ggcggtgcag atgttggagg tcgccttgtc
     2161 gcggcgaata tgctgttccc tcgtttgcag ggccaggcgg taggccgggc ggcccagggt
     2221 atctatggac atgccgataa ggcggccggg catgcggcgt ttgagagcgt ccgtgcagga
     2281 catgtaggcg gcatgggggc cgccgaagcc cattgggatg ccgaagcgct gcgtgttgcc
     2341 gatgcagata tcggctccga aggcgccggg ttcccggatg atggtaaggg ccatgagatc
     2401 cgccgccacg acgcagagcg cgcccgtggc atgcacgcgg gaaaagaagt ccgtgtagtc
     2461 gcagatgcgg ccgagcgtgt ccggatattg gacaagcact ccggccagat ccgcaccgat
     2521 ggatgcgggg tcaaaggatg agcaatctcc cacgatgatg ttaacgccct ggaaggcggc
     2581 gcgggtacgg atgacgctga tggtctgggg gtggcaggtg tccgccacaa agaaggtgtt
     2641 tgctttgggg cgcgcgttcc ggcacatggt gacggcttct gctgctgcgg tgccttcatc
     2701 cagcagggag gcgttcgcta ccggcagtcc tgtcagggaa gagaccatgg tctggaaatt
     2761 catgagcatt tccagccgtc cctgggcgat ttccggttga taaggggtgt aggccgtgta
     2821 ccagccgggg ttctccagta cattgcggag gatgacggag ggagtgatgg tgccgtaata
     2881 gccctggcca atgaaggttt tcaggagctt gtttttccgc agaatggaac ggagttcctc
     2941 cagggcttcc gtttccgatt tggctgcggg caggtccagc ggggccttca tgcggatatc
     3001 tgcggggacg atgtccgcaa tgagttcgtc aagcgtccgg tagccgaggc tgtcaagcat
     3061 ttcccggcgt tcttccccct gggggccgat gtgccggctg gcaaaatctg agtgggtatt
     3121 catgtggtat ctctggctgg taatagcgtc cggccgcgga acgggccaaa caaaatgccc
     3181 cgggatggaa tcaccggggc gggggaggga agaatggttc aggagcagta ttcctcgtaa
     3241 tccgtggcgt tcatcatatc ttccgtttcc gtgggaacgt ccaggcggat tttgtacagc
     3301 cagcctgcgc cgtaggggtc ggagttaatg agggacggat cattggaaag ctcttcgttc
     3361 acttccagga tttctcctga aacgggggtg tacacgtcgc tggcggcttt gacagattcc
     3421 acgacagcga cagggtcgcc ggctgcgacg gtggcgccta cttcgggaag gtctacaaag
     3481 acgacatcgg agagttcggc ctgggcatgg tcggaaatgc cgatggtgcc gatgtccccg
     3541 tcaatttcaa tccattcgtg atctttggaa tacagcagat tttctggtac gtcgtgcata
     3601 agatgtaatt gtttgaagtg agagtgtagt aaaatgaggt gtttgtcagt ttatttttgc
     3661 gccgtagtgt cagccttttt tataaaaggg tttttttacg accacggctg ggaatttcct
     3721 tccccttacg tcaatttcca gctccgtgcc gaccttggca taggcggcag gcaggtaggc
     3781 cagggcaatg cccttcatca gcgaaggaga gagcacgccg ctggtaagtt ctccgatggc
     3841 ttctccgccg gggacgtgca cggcatagtg ggcgcgggga ggagctccct tgccggtgta
     3901 ttcaatagcg gccagccgac ggctgaggcc gttggctttt tgttcccgga gaatatcgga
     3961 accgatgaag tccgtatcca gcgcgcagaa gaatccgagc ccggcttcca gaggcgtttt
     4021 gtccggagag aggtcggagc cgttcagagg atagcacatt tccagacgca ggctgtcgcg
     4081 ggcgcccagg ccgcagggtt tggctcctgc tccaagaaag gcttcaaacc atttgacgcc
     4141 ttccttagcc gggcagaaga attcaaaacc atcttccccg gtatagccgg tgcggcagat
     4201 aatgagatcc gtcccttccg ccgtgatgcg ggagattcca ttgcgggggg gaagttccac
     4261 gccggggatg acgcgggaga atacttctcc gcattcggga ccttgaacag ccagccccac
     4321 gtattcgtcg gagtggtttt ccagagttac gcctgcaggt tgatgggcgg aaagccatgc
     4381 gaagtcttca tcaatcttgg aggcgttcac cactacgaag aaggtttccg gttccatccg
     4441 gtacaggatg aggtcgtcaa tgactccggc cctgtcattg agcatgacgg agtattgccc
     4501 ctgccctaca ttcagtttgt tgatgtcatt ggtcagcatg gagttcagcc atgctgcagc
     4561 ggaaccgccg gctaccgtga actgccccat gtgggagatg tcaaaaatgc cgcaggtttc
     4621 gcgcactgct ttgtgttcgt ccagaatgcc ggtgtactgc accggcatat tccagccggc
     4681 gaaaggaacc attctggctc ccagttcaac gtgtttagtt gccagggggg tggatttgac
     4741 gtctgtatca gtcatgaggc gatgtgaagg ttatgagcaa tctgcccctt atatcagtaa
     4801 aagtcaatgg aattccggta acgcttccgt ctagacattg aagcggaatt cgatgacgtc
     4861 cccgtctttg acgacatatt cttttccttc gatgcgcagc ttgccgtgtt ccctcgctcc
     4921 ggccttgccg ccgcaggaaa ccaagtcgtc gtagtgcact acctccgcgg cgataaaacc
     4981 gcgttcaaag tccgtgtgga tgacgccggc cgcctggggt gcttttgccc cggccggaat
     5041 ggtccaggcc cgcgtttcct tgattcccgt ggtgaggtag gtgcgcaggc ccagaaggtg
     5101 gtacacggcg cggataaggt cggaaacacc ggagtccttc acacccaggg attccaggaa
     5161 ttcgcgggat tcttcctccg agacgtcgat gagttcctct tcaatccggg cggagatgac
     5221 aatggcttcc gcgttatggt gttccgctac gtattttttc acctgggaga cgtagggatg
     5281 ggcgtccggg ttggagatgg cgtccgccag ttcgtcttca ttgacattgc aggcgaaaat
     5341 gcttttttta tccgaaagca gctggaaaga atggagcagc ttgcgttcgt cgtcgtccag
     5401 ctgcggttca agggtgaggg cgggattgcc ttcgttcagg tggggcagga gtttggtgat
     5461 gagggccact tcggccttgg cttccttgtc gccgctgcgt gccttgcgtt cgcgggaaga
     5521 gagtctcttt tccatggtgg cgatatccgc cagaatgagt tccgagttga tgatgtcaat
     5581 gtcgcgcaga ggatccacgg aaccgagttc atggataata tcatcattgt caaagcagcg
     5641 gactacctgc acgatggcgt ccacttcacg gatgttcgcc agaaactggt tgcccaggcc
     5701 ggctccttcc gaggctccct tgaccagacc ggcaatatcc acgaattcaa taagcgtggg
     5761 gatgattttt tcagaaccgg acatgtcgga aagaacctgc aggcggggat ccgggactgt
     5821 taccataccc acgttcgggt caatggtgca gaagggatag ttggccgcct gggccttgcg
     5881 cgtccgggtg accgcattga atagagtgga tttgccgacg ttggggagac ctacaatacc
     5941 tgcctgtaac ataggcagga ctgatagcgg gtcacgccgt gaaagtcaaa taccaattgc
     6001 cgacgggcat ttatgcggcg gatcccaaag cccatctgat caggttttcc gattccgtcc
     6061 agatacggga cggatggcag ccgaggacga cgacgatgac atggcgcccg ttgacgccgg
     6121 ctgaggaaac caggcagcgt ccggcggcgt tcgtgtatcc ggttttcatt ccggtaaccc
     6181 aggggttctg tgtgagcagc ttgttggtgt ttctcagcag aagcgttctg ccgttggctc
     6241 gggtaaaggc atattggcgt ttacagataa tattgcgcag ttccgggttg cggtacacgt
     6301 aataggcgca gcgggccatg tcaatggcag tggaatattg atctgccggg aggccgttgg
     6361 gattggcgaa gcgtgagttg tacatgccca tctgccgggc tttggcattc atcaactggg
     6421 cgaaacgggg aacggaaccc gccgtatcgc gggccagagc cagggctacg tcgttgaaac
     6481 tgcggatcat catggcattg agcagttcgc ggcgtgaata gacttccccc gcccggaatc
     6541 ccagtttggt ggggtccgct ttggtatcgg aaggctggat gaccactttt ttgtccaggc
     6601 tgccgtgttc catcacgacc atggccgtca cgagtttctg cgtgctggct acctggcggt
     6661 gctggaggcc gttgtgggaa aagagcactt tgccggtgag ggcgtccata acgcaggcgc
     6721 tggcgcagcg gggcgtgcgt ggggcgcttg aggggatggc tacaggacgt gtggggaaat
     6781 tggccggtcg ggggagggca tgggaaaccg gctgggagag ttgtggggga acgggcgttg
     6841 cgagggggat gtagtcactt gaatccccgt acgattggca gcttgtggag ctcaggcaaa
     6901 gggagaatcc tgcaagaagg gcgaataaac gcatgtcttg ttgctacagt aagaagtttc
     6961 gttcatcaag cccaaactcc gcatttgaaa gagagccgga cgaaaaaggc cgcggatcgg
     7021 acaatccgcg gccttttctc tctattaact acctatggaa ccaaaaacca ccctgaacgg
     7081 attttgaatt gctttttcca tccgtcggac agatcttgtg aaggatgaga ctccaggcag
     7141 gagggatgcg ttcaaaatat attcgtcaac agttcttttt aagaggtgtt gccgtatgcg
     7201 cccgagcctg cgtccagtaa atatggcaga aattttttcc gaacatattt tgtttttcgc
     7261 gggcatgtaa atttgccgca ggcatttaaa atgccgggga tgtcctgccg atatatttaa
     7321 tttttggaat aaaaattatt gaaggaaagg atttggcgac tattttgaga cgtttttttt
     7381 gcgtccggat ggaaaggttt ttatacggga gatggacggc gctcccttcc ggttccatgg
     7441 tcagggagag gaggcccgga cctggcgttt tccccggcgg aaaagcggaa tctgcctaaa
     7501 gttccctgcc gttaatggag aaataccctc cggcgtccgg agtaatttgc cctgcaattt
     7561 gcattttggc caaaagcggg gtgatggtat gcgccgtttt tcccagagag gtgcagaggg
     7621 tgtcaatagt attgaaaccc agtctgatgg cgtggagaat ctccttttct tccaaagtgg
     7681 gaagcggtgg ggttgaggct ccggcagggg gacatggcga gaagagaggc agtccctgtt
     7741 ccggaacggc ccagttcatg tcctgcagaa tatcggaggc tccggtagcc aggatggctc
     7801 cgtcccggat gagggcatgg catccgtcgg aagaatgccg gtcaaccggt ccgggaatgc
     7861 aaaaaacgtc tcgaccctgt tcggccgccg ttcgggccgt gatcagggcc ccgctgcgtc
     7921 cggacgcctc caccaccagc gtagcgcggc tccagccgct cacgatgcgg ttgcgcatgg
     7981 gaaaagtggt gcgggagggg ggcaggtcca ttggaaactc ggagactacc gctccatgcc
     8041 cgtccgcaat gcgctgcgcc aagtttctgt tttcccgagg atacagtttg ttgagtcctg
     8101 ccccgataac ggcgatggtg cgcccctccg cgtccatggc cccggtatgg gcttccgtgt
     8161 ccacaccgcg cgccagtccg gaaatgacgg tgactccggc ttccgccagg tcatgggaga
     8221 tgtttctggc gcaaagcctg ccgtaatggg tggccatccg tgagccgacg acggcaatgg
     8281 agcgttcggc atccgtcccg gtccagtttc cccaggagta gaggacaatg ggcgggtctg
     8341 ggagagcacg cagggaggat gggtaggagt cgtcaaaaac cgtggttact gcggcccccg
     8401 cgttatccgc cagttccagt tccctgtacg ggttgacgat gctccgccaa gaggaaatgc
     8461 ggcaagccag ctgcgctccc acgccgggaa tttccatcaa cagggaggaa ggggattcca
     8521 gaatcagttc cggagaggcg aatacctgca ggagacgcat gattctgaca ggacccaggc
     8581 ccggtatcag gttcagggct atggctgctt cccggggtgt catgaataag gggtcagttc
     8641 ctggtaaacg tccagatggg cttgaatcat atcctgcata ttgtaagggg aaggaatttg
     8701 ccggggcagg ggggggggct gggcatgcca gcgggccagc aggtccgcca tggcggcggt
     8761 atctcctacg gcgacgttcc cttcaggaag gaaggcgtcc agctgttcct tgactccgcc
     8821 gtgggcgtat ccggccacgg gtttgcccag ggcgagcgcc tccagggttg atttgccgaa
     8881 ggcttccggg cttttggtca gggagagggt gacggaacat gtggaaagga tttccctcag
     8941 atcctggcga tgtcctgtcc aggtgaagga ctgggagacg ccggaacgtt ctattgcccg
     9001 caggacctcg tttttatatt cttcttttcc cttctttgct tctcctacaa tgacggcgtg
     9061 ggccgggatt ccctgttcca gaagctgcct gacgaccgga atcagatcca gatgcccttt
     9121 caggcgcgtg atgcggcccg gcaggcacag ggtgaatttc cccttcagtt caggatagga
     9181 catgaaccag cccgtgagcc attcccggga gggggagtag gccgggtgat attggtccgg
     9241 ggaaatagca ttgggtatga ttctgatatg gtccggaggg gtggacggat aatggtcaag
     9301 gatgtagtcc ctgatgcagt tggagacggc gatcaccctc tctccccggc tcatgatggc
     9361 ggagtaccgg ttgacggagt agaagccgtg aacgctggtg acgaggccgg ggcggtcttc
     9421 cggcgggagc tttttccatg ccaggtagcc tgcccacgca ggaacgcggg aatggagatg
     9481 caggatatcc ggcctgacgg cctgaagcag ggcgcggagg gccccgatgc ggaagagagt
     9541 ggagatgctt tttttgccta tcggcatcag gatgtggcgg gagccttcct tttccagacg
     9601 gggcaccagg cgtccgcctc cggaaacgac gatattttcc acgccccggg aagaaaggcc
     9661 gctgcccagt tccataacga cttgttccac gcctccggat tccatggagg ggacgagatg
     9721 tactattttc atagggcgcg gagctgaggg aaaaatctgg agaggatgta gtctgctgca
     9781 cggtccgctt ccagaagcgg ggaaccggga gccgtcaggc ggaagttctg ttttttccag
     9841 tcactgtatc cagtaaccat gccttccttt tccagtgtct ccaggccgga caggatgcgg
     9901 gatttgcggc tgccgtgtcg gcgcggtacg gaaaggatgc ctacaggcgc gccggagcca
     9961 agagcctcat ataccatgga gacgctgtcc tggctgaccc aggcggcgga ggcgtgcgcc
    10021 agatgccggg ctacccaccc cggccgggtt tcctccacgg gaacgacggt tagttccgga
    10081 acggccgtcc ggattttttc cgcaaagccg tccggcgtcc ggcgcgaggt ggttagaaca
    10141 aggtgtccgg gggtgtggat gctgatggac gcgagctggt tgagcatgct ttcgtcatcc
    10201 cagtcaaaat ctttgctggg ccctcctatg agaatcagtg tggtatcctt tggtacggag
    10261 ggatccggcc tcatggggtg gagagctccc tgggtgggga agatatccgt atccgtgtaa
    10321 tcgcggccgg aatccaggtc atggcgggga ataaggcaga ggtcgaaaaa ggagcaggga
    10381 agcgtaggct tcatgcagag gacggcccgg gttttgaaat ggtgccgcgc gcagatgagc
    10441 gggatatgcg ttgcatgtcc ggcggaaatg aacagatccg gccgtggaat gtcgctgcct
    10501 gtgacgacct tccggatttt ccccaaaagg gaaagcccct gcaggtccac cgtttccacg
    10561 gttccccccg ctttggagat cagagcctgc gccagcccca gggactggtt gaggtggccc
    10621 tgtttcccat cgctcagaat ccggatgttc atatatgcgg cattatgaag cggcggcggg
    10681 gtgcaggcaa tccaatttcc accggacaga agaaaattct tggtgggagg catgctcttg
    10741 ttcatgattc cggcgtgctg actccggatt cctctgttat taaagattcc ttgtgcgccg
    10801 tgtcccggca gcttggtttt tccggctgcc gggtggcccg tgcggaaaaa agcccgcatg
    10861 cggaaaaatt gtttcaatgg ctggagcgcg gatggcacgc cgggatggag tggatggcgc
    10921 gttccccgga gcggcgcacg gatcctgcgg aagtgcttcc cggatgccgt tccgtcattt
    10981 gcctgtccta tgattatgac agccccggta ggcgcccgga gggggagggt agcatttgcc
    11041 tttacgccca tggaaaggat taccacggaa ttctggagga aaaactggcg gatttgcagg
    11101 agctgctttc catttacggc gggaagcaga gggggtatgt ggactccggc cctgttatgg
    11161 aacgggacca tgcggaggcc tgcggcctgg gctggcgcgg gaaaagcggt ttgatcgtgc
    11221 gcaggaaagg gggctctcgc ttttttatcg ctaccctgct gactacgctg gaactggaac
    11281 cggacgctcc ggtttcaaac ggatgcggca gttgccgccg ttgtgcggcc ctgtgtccga
    11341 cgggcgcaat tatggaaaac ggtcaggttg atgccggacg ctgcctttcc tactggacga
    11401 ttgaacaccg gggggctatt ccggaagaaa tccgtcccct gataggcacg cgcctgtacg
    11461 ggtgcgatac ctgcgtgacg gtctgtccct ggaatggtaa gcctttgccg gacgttgacg
    11521 aacggttccg catgtcccgt ctgctggctt ccattcccct gcgtggtctt ctttccctgg
    11581 atgccggcgg ttttgcggcc ctgttccgga attccccgtt gaaaaggctc aagagggaag
    11641 ggctgctgcg taacggctgc gttgtgctgg ggaatgcggg gactccggat gacattgatt
    11701 ttctgaaggc gctttacggg gagtctcctc tggtggagga acacgcttcc tgggctgtgg
    11761 agcgcatcct ccgccgccac gggcggcatg catcttcaag cggtgcaaga gattaaaaat
    11821 agaaaaaatg atgttttggt cttgtcaaaa cctcaattta tggtatccat cttgccccaa
    11881 gcaatagctc tgcgcgaggc agagaaaaat aacagctagc aaatccaatc cattatggca
    11941 cgccttttcg gtacagaaat acccaacgag aagcgcatcg aggcttccct tccgtatatt
    12001 tacggaattg gtcgctcgac ttctaagaga atcctggaac aagcaggcat caatcccgac
    12061 atccgcacgg gacagcttac cgacgaacag ctcacgaaga ttgttcaagt aatcaccacc
    12121 gacggcattt tgattgaagg tgaccttcgt cgtgaaaagc aatccattct caagcgtctg
    12181 acctccatca actgctatcg tggtcagcgc caccgccgcg gccttccggt acgcggtcag
    12241 cgtacccgca cgaatgcccg cacccgtaaa ggcaagaaga agaccgttgg cgcgcaggcc
    12301 aagaagaagt aatccgccaa cctgaatttt taatatagct ttactatggc tagcgaagaa
    12361 atcaccaacg aaaccgccga acagcctgtg gaagcggcag cttccgctcc cgtcgctgaa
    12421 actccggccg ccgctgtttc cgctcctgaa gaaatcaaga agcccgaacc ccgcaaggat
    12481 atctttgcgg aacttggtct gggcggcgat gatgacaagc ccaaaatcct gaaggccaag
    12541 ggcagcaaaa acgtttccac gggcgtggtt cacgtttcct ccacgttcaa taacaccgtc
    12601 gtaactgtga ctgaccagcg cggcaatgtc atcggctggt cctccgccgg caagatgggc
    12661 tttaagggtt cccgcaagag cacggcctat gccgggcagg tggtgtgcca ggacgcctgc
    12721 cgccaagcca tgggtcacgg cttgcgtgaa gtggaagtgc gcgtaaaggg gcccggttcc
    12781 ggtcgtgaat ccgccgtacg tgccgtgcag acgatcggta ttgaaatcac ctccatcaag
    12841 gacgtgaccc ccatccccca caacggctgc cgtcctccga aggcccgccg cgtctaattg
    12901 agaatctttt acctatatag atctaatata tcatggctcg ttataccggt ccccgcgata
    12961 aagtgtcccg ccgttttggc gttgcccttt tcggttccac caaggctctt gaaaagcgcc
    13021 ccttccctcc cggccagcat ggcatgcgcg ccggccgcaa gaagaaatcc gactatggcg
    13081 tgatgcttgc tgaaaaacaa aaactgcgtt tccagtacgg tgtgcttgaa ggccagttcc
    13141 gcaagtatta tgcagaagcc gcccgccgcc gcggcattac cggcgatatt ctgcttcagc
    13201 tccttgagct tcgtctggac aatgttgtgt accgcctcgg cttcagcaat acccgtgccg
    13261 gcgcccgtca gcttgtttcc cacggtcaca tcaccgtgaa cggcaagaag acgaatatcg
    13321 cgtcctactc ctgccgtccg ggcgacgtca ttgccgtagg cggcaaggct tcttcccagc
    13381 agctggttac ccgtttcctt gacctgactc aggctactgt ggttcctgac tggctggaat
    13441 gcgaccgtga caagctcacg ggcaagattg cccgcgtgcc ttccaaggaa gagattgctc
    13501 ccatcgtcaa cgagcagctc atcgtggaat tctactcccg ttaatcttat ttccttctgg
    13561 atttgcttca aaaccccggt tgcctttcgg cgaccggggt tttgggcatt cagggggagg
    13621 ggcatggaag agttgggtgt tgagagttaa gggaagcggg tataggatga aagcatgacg
    13681 gacgattgga aaaaaagagg cgcagcgctt ttcgatatgg acggcacgct ccttccctgg
    13741 gatacgcaat atgttttttc ctgttttgtg gtgaggcgcc acccttggag gcgcttgctg
    13801 atttttcttt tcctggcctg tatcccgctc tatattttga gaatatggga tgagaaccgg
    13861 atgaagaggg cttatctcat gtatttgtgg gggcttcccg ctgaaacggt gcgggaatat
    13921 ggacggaagt ttgccgagat ggcgcaggaa tggatttatc cggagctgaa ggagcggctg
    13981 gcagggtatc ggaagaaggg ttatttgtgt ctcatggttt ccgcttctcc atcattttac
    14041 gtgaagcctc tgggcgaact gctgggattt gacgaagttc tgggaacgga tgtgcttctg
    14101 gaggaacgca tgccggcaat gccggaactg ccgaacggta ataataaggg ggcggtgaag
    14161 gtggagcgtc tgcgggagcg gaatgtactg ccggaacatg gtgttctgga aaacgccgtt
    14221 gcttacagcg acagtgccgc ggatctgccc atgctgcttt cctgcaggcg gagggttctg
    14281 gtgaatcctt ctcctgccct gaaagaagac aggcttctgg atggtgcgga gtgtctgtat
    14341 ccggccaggc cttggaaggg aaggtttggc aagatatgga gaattggatt ttttgtcatg
    14401 ggactggtga atgtaaataa tgtgaaatca atgatttgct gatttatcaa gagaaaattc
    14461 tttacttttg tgacgaaaat gtttcacttt tcttaacaag gggggaaaaa gcatttttct
    14521 ttccatgtta gcaaatcaac aattaatacc ctaaccaagt aatagtcatg caaaccaaga
    14581 acatcatcag tgttgcggca gttgtggcat cctttgccgg agctgctctt gcgggtactc
    14641 ccgtcaagat tgttgctccg actccggttc ccgctcctgt ggcgacttcc agcccgctgt
    14701 ccggcgatat ttacgccggc tacgcttcca attacacctg ccgcggcatt gtggc
//
