LOCUS       c00020_gnlPro..        14248 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ENJNNFCD_20.
ACCESSION   c00020_gnlPro..
VERSION     c00020_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 09:25:54
            Original ID  :: gnl|Prokka|ENJNNFCD_20
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 20463
            Orig. end    :: 34711
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14248
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[30463:33928]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13465
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14248
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14248
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(455..1045)
                     /locus_tag="ctg20_28"
                     /transl_table=11
                     /translation="MSGLANAFLALLPPDQASLPAAGAEARWLADTAVVQSAAIARDNR
                     TVLFGWLNNILVNSNLRDRGLCWQVQQDLYRDLRRRPVKYFRIGLTIRDRGTGREHSCV
                     YVNAVGKGLQGSIVLDAWKNCGHLVTLTQKDREGGKWEEDWREPFVSKAFPEGHSYGME
                     HHLVWPGWARKRPMLVQRIFQSDQQNEAKAAAE"
     CDS             1285..2895
                     /locus_tag="ctg20_29"
                     /transl_table=11
                     /translation="MLTIKNLTKSHAGRTLFRETEMTINWGERVALVGPNGAGKSTLFR
                     MILGEDTPDEGSISMDEYAIVGYLPQEASEPKDETVLEIALGITPEMEQAIHTIRTAEN
                     ANKTDTPEYAEAIDTFNAANGYQLEPKAKKILKGLAFRESDFHRPAREMSGGWIMRAYL
                     AKLLVLEPDLLMLDEPTNHLDLLSLLWLQRYLKNYPGAILMISHDRDFMDELVESVYDI
                     DNEELVEYRGNYSDFLQQKDVRFEQLQAAYRNQQKEIAHIQEFIDRFRSINSKAGQVQS
                     RIKQLEKMKIIQKPVARRKVFKFNFPQPPRSTQKVIELEKVCQSYGDRRVYENLDLLVE
                     RGERTVLVGPNGAGKSTLLKILAGIIPIDSGQRTPGTTTRIGYFSQARTENLNPENTVL
                     EEIMKCSAEIREEEARSILGSFLFRRLDVEKRVSVLSGGEKSRLSLVKFLVDPPNLLLM
                     DEPTTHLDLLSVEALVQALKHYEGTLVFISHDVHFIRSLAQKTLHVNRGTITAYAGGYD
                     YYLEKSGILDDEKGGITAE"
     CDS             2959..3477
                     /locus_tag="ctg20_30"
                     /transl_table=11
                     /translation="MKAFLVPLLYSALLSGASLAFGETAAGTASPAAAAPAEKIPSAES
                     LINQAFSFAINIQQTLAGVQDKESVDNAVKTLQDIQKDIRHFLQLQDKLNDAEKEKEDA
                     LIEKMEKRMEMLDNRCRQEGKRLFEARYYGSAALKDILENSDEFSDLVEPDEDGAPPGA
                     LRENEEAGQ"
     CDS             3422..4351
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg20_31"
                     /sec_met_domain="adh_short_C2 (E-value: 3.7e-75, bitscore:
                     244.0, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTGRPPVHSGKMKRPDSSPPPRFSPLFFHSRHAPSPYGFLRGQV
                     HFKLAGTVKNGFTVGSMQKLAGKTAIVTGAGRGIGNAVARRFASEGARVILISRSPSSC
                     GGAAEEINKEFPDSCKAYPCDVADYAAVQETMAAILKDFPQIDILVNNAGITRDSLMLR
                     MKEEDWDAVLDTNLKSAFNTVKALQRVLMKSPAGRIINMSSVIGLVGNIGQANYAASKA
                     GLIGFTKSLAQEFAPRKVTCNAIAPGFISTEMSNAIPDNLKEEIVKKIPLKEQGSVEDI
                     AALTAFLASDDARYITGQVIACDGGMTM"
     CDS             complement(4303..4785)
                     /locus_tag="ctg20_32"
                     /transl_table=11
                     /translation="MLRTFVRFPVRLFRGTPHEERSSRYGDHAQGSFRHGNRFRVGFKT
                     CRISGSFNELMDLARCADQLPGRQVIRNGKGRTGSAVQFPFLQRGSAFSPLACAGNARG
                     IFRGRAGGIIFFPAPGQQGASSQKAGNKENAAHGMEKTGMPYIVMPPSQAMTCPVM"
     CDS             4852..5580
                     /locus_tag="ctg20_33"
                     /transl_table=11
                     /translation="MENGRPRAKDGQLLEEQPDDELWDSVTQPTAPYTAMNLGMGHGYE
                     HGLPAISMSHHAASKFCEWLSAQTGHYYRLPTEAEWEYACRAGSPGAYSYGNGEASLDQ
                     YAWYWNNSNDRYQKTGSKKPNKWGLRDMHGNVAEWVLDSYVPDAYGKRSGLPAKDPLVI
                     IPSAPHIVRGGSWEDDPDSLRSAARRASTPAWNRQDPQNPKSIWYLTDGGMIGFRVVRP
                     MNIPDIMTMHRLWNFSKGEP"
     CDS             5594..5794
                     /locus_tag="ctg20_34"
                     /transl_table=11
                     /translation="MTIALRTEQSSDHAETEHVTREAFWNYFVPGCHEHYLLHIMRVSP
                     SFIPELDAVAVHGSRIVGKHR"
     CDS             5906..6040
                     /locus_tag="ctg20_35"
                     /transl_table=11
                     /translation="MYAAALQVCELQRGSLSGLKGHYVKAAVYHMDEKRAAEFDGISR"
     CDS             complement(6258..6998)
                     /locus_tag="ctg20_36"
                     /transl_table=11
                     /translation="MKKTLTFLIAMGSFAVSSEAATVFNYYTPGTDNYNSTIHGFYLGL
                     GSSSLAPSDSSSPSSLSGEIRLDSFTLRGAANNLGANVTYGFLVLNGSDNSVIGWSTNT
                     GTTAAGINLTFSFSSLDGSPLLLDAALTYRFLAVSQSVMDLMQDTSKTYLYAAGGTAAP
                     TANTEGDTVTISGGLTAPGIRGHYDAEGAPGDSVVITGANGTNTFSLLSPIFTEIRGEM
                     VPEPATVSLGLLGLAALMMRRLRA"
     CDS             7173..7262
                     /locus_tag="ctg20_37"
                     /transl_table=11
                     /translation="MNYKYNILTLNIFNCLRIPNSLFKRKCIH"
     CDS             7293..8168
                     /locus_tag="ctg20_38"
                     /transl_table=11
                     /translation="MKKLLSTLILSAGMSLSATANTTLLDSSIVGYSDFTSQTADFGTL
                     KDSVSITSDDSNLTLSGITFNGYGTNNRDVMSVTMVLDLSKINTPETYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYSGPVVDTPLGMEGSLTISVVTGDLGTRIYFGDSATYYS
                     NSGLKFGNQQIDQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXFSLSVQTSAEKTEGKSFHLLR
                     QPHGQHLTEK"
     CDS             8269..8676
                     /locus_tag="ctg20_39"
                     /transl_table=11
                     /translation="MQSPASLSIRNSPSFQQSISPHGPDRCGSVRRQQTPSPKQGKGVG
                     KWLSLNLYPPFPSMNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPDE
                     FLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(8710..9525)
                     /locus_tag="ctg20_40"
                     /transl_table=11
                     /translation="MMAFIEPHIHMVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSAD
                     GFRDYFVQLTECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLG
                     IGEIGLNRNTSHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLD
                     PCRVLVDHCEEHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADW
                     GDSDPLALTALACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(9528..9800)
                     /locus_tag="ctg20_41"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             10001..10702
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_42"
                     /sec_met_domain="SucD_FumR (E-value: 1.9e-13, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             10724..11302
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_43"
                     /sec_met_domain="FAD_binding_2 (E-value: 3.9e-19, bitscore:
                     60.5, seeds: 62, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGWTTAPSAAPSSSEPSTHADR
                     RASSSCWVPTRPWKRKWPRDTLKCSPAMK"
     CDS             11281..12663
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 86.4; E-value:
                     7.1e-27)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_44"
                     /sec_met_domain="FAD_binding_2 (E-value: 5.3e-27, bitscore:
                     86.4, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 4.7e-38,
                     bitscore: 121.7, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFSRHEMMDLVLVDGEAKGIVTRNLVTGEIKSYAGDTVLLCTGGY
                     GNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVKGDYQSKLTLMSESLR
                     NSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFGNLAPRDISSRAAKEA
                     CDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEITDDDPHETPMMIYPA
                     SHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQGLSDGYFVIPATLPA
                     YLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFHRELGLIMWEDCGMAR
                     TEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVADFLEFAQLLCYDALNR
                     QESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLHKEPLTFENVHLAIRS
                     YK"
     CDS             12641..13465
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg20_45"
                     /sec_met_domain="Fer2_3 (E-value: 1.9e-23, bitscore: 74.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LPSAATSKDSQYINTQKKDYNMAKTLNLTLKVWRQENREAKGRIE
                     TYAAKDIPVDASFLEMLDIVNEGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPER
                     QVTTCQLHMRKFKDGDTVWIEPFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAP
                     NANNIAVEKVKADAAFDXXXXXXACVASCKNASAMLFTSAKIAHLNLLPQGQPERSKRV
                     LAMMKQMEAEGFGNCTNQYECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             14013..14246
                     /locus_tag="ctg20_46"
                     /transl_table=11
                     /translation="MNPPHRSAVPGYRKWYFGAGGSPGRRGMEAAPEPDPLPFEAIRIH
                     EERNVGPPSTSADGYSAHGTFTIPEGAEGKKLY"
ORIGIN
        1 gacatggaac aagaaaatct cttgatttct acttgccacc atttacattg gtgccagcaa
       61 acctccgtgg atgcggaggt tccagtagtt aacaaacact gtatttaatt cgaattatga
      121 agaacatcgc tatcctcgcc atcgccggcg ccgcttgcct ggtcgcttct tgctcccagc
      181 agcagcagca acagcaaacc accgctcctg ctcccgctcc ggttgtgcag gccaagggca
      241 agtaagtttg cagcggggtt ttgccctgca acactagcaa attatccaat taatccgcac
      301 tcggtgtacg cactgagtgc gtttttattt gccctgagtc cggattccct ccgccatttg
      361 ccgattcgcc gggattttcc ttaaaaacgg cggataccgc aaaccgccgc ggcgcagcac
      421 cgtgtgccgg ttcctgccgg atcaggcttc ccctttattc agcggccgcc ttcgcctcat
      481 tctgctgatc ggactgaaat atccgctgaa ccagcatggg gcgtttcctg gcccacccgg
      541 gccagaccag gtgatgttcc atgccgtagg aatggccctc cggaaaggcc ttggaaacaa
      601 atggttcccg ccagtcctcc tcccatttgc cgccttcccg gtccttctgg gtcagcgtca
      661 ccagatgccc gcagttcttc caggcatcca gaacaatgga gccctgcaat cccttcccca
      721 cggcattgac atacacgcaa ctgtgctccc tgcccgttcc acggtctcga atcgtcagcc
      781 ctatgcggaa atacttcacg gggcggcggc gcaggtcccg gtacaaatcc tgctggacct
      841 gccagcacag ccccctgtcg cgcaggttgg aattgaccag aatattgttc agccagccaa
      901 acagcacagt cctgttgtcc cgggcaatcg ctgcggactg gaccacggcc gtgtccgcca
      961 gccacctggc ctccgctccg gcagcgggaa gagaggcctg atccggcggc agcagcgcca
     1021 ggaaggcatt agccagcccg gacatttgct gctgcacgta aggttgttgt atataatcct
     1081 ccgccggagg agtacagcag gaactccatc cgcacaaaag ggcggcagca agcaaaagcc
     1141 tgaatgtctg cgtggtcggc atggcgcgcc aaggctagca gactacgcgt aaaaatccag
     1201 taaagctttc aaaaatgcct gcctccgccc tgacggctct tgccttcccc tttccatccc
     1261 ggtagaatac atcctctctt caccatgctg acgatcaaaa atctcacaaa atcccacgcc
     1321 ggacggacct tgttcaggga aacggaaatg accattaact ggggggaacg ggtggctctg
     1381 gttggcccca acggagcagg caaatccacc ctgttccgca tgattctggg agaagacacg
     1441 ccggacgaag gctccatcag catggatgaa tacgccatcg tgggctatct tccccaggaa
     1501 gccagcgaac cgaaggatga aaccgttctg gaaatcgccc tgggcatcac gccggaaatg
     1561 gaacaggcca tccacaccat ccggacggcg gaaaacgcca acaaaacgga tacgccggaa
     1621 tacgcggaag ccattgacac cttcaacgcc gccaacggtt accagctgga gcccaaagcc
     1681 aaaaaaattc tcaaagggct ggcctttcgg gaaagcgact tccaccgccc cgcccgggaa
     1741 atgtccggcg gctggatcat gcgcgcgtac ctggccaagc tccttgtcct ggagccggac
     1801 ctcctgatgc tggacgaacc taccaaccac ctggacctcc tgtccctgct gtggctccag
     1861 cgatacctga aaaactaccc cggagccatc ctgatgattt cccacgaccg ggatttcatg
     1921 gatgagctgg tggaaagcgt gtacgacatc gacaacgaag aactggtgga ataccgcggc
     1981 aattactcgg acttcctcca acaaaaggac gtgcgcttcg agcagcttca ggcggcctac
     2041 cgcaaccagc agaaggaaat agcgcacatt caggaattta ttgaccgttt ccgctccatc
     2101 aattccaaag ccgggcaagt ccagagccgc atcaagcagc tggaaaagat gaaaatcatt
     2161 caaaaaccgg tagcccgcag gaaagtattt aaattcaact tcccccagcc tccgcgcagc
     2221 acccagaaag tcattgagct ggaaaaagtc tgccaatcct atggcgaccg cagggtttat
     2281 gaaaacctgg acctgctggt agaacgcggg gagcgcactg ttcttgtagg cccgaacggc
     2341 gcgggcaaat ccactcttct caaaatcctg gcgggcatca tccccattga ctccggacaa
     2401 cgcactcccg gtaccacgac gcgcatcggc tacttctccc aggcgcgaac ggaaaacctg
     2461 aatccggaaa ataccgtgct ggaggaaatc atgaaatgca gcgctgaaat ccgggaggaa
     2521 gaagcgcgtt ccatcctggg ttccttcctg ttccggaggc tggatgtgga aaaacgcgtc
     2581 agcgttcttt ccggcgggga aaaatcgcgg ctcagcctgg tcaaattcct ggtggatccg
     2641 cccaacctcc tgctgatgga cgagccgacc acccacctgg accttttgtc cgtagaagcc
     2701 ctggtgcagg ctctgaagca ttatgaagga acactggtct tcatctccca cgatgtgcac
     2761 ttcatccgtt ccctggcaca aaaaaccctg catgtgaacc gggggaccat caccgcctac
     2821 gcaggtggat atgactacta tctggaaaag tcaggcattc tggacgatga aaaaggcggc
     2881 atcacggcgg aataaggctc ttttttcagt ttcccctttt tccttgccgt ggatttcatc
     2941 ctgccttaaa agaacaggat gaaggctttt cttgttcctc tcttatattc tgcgcttctg
     3001 tccggagcct ctcttgcatt tggtgaaacg gccgccggaa cggcttcccc cgcagcagcg
     3061 gctccggcgg aaaaaattcc ttccgcggaa tccctgatca accaggcctt ttcctttgcc
     3121 atcaatatcc agcagacgtt ggcaggcgtt caggacaagg aaagcgtgga caacgccgtc
     3181 aaaacgctgc aggacattca gaaggacatc cggcatttcc tccagcttca ggataaattg
     3241 aacgatgcgg aaaaggagaa agaagacgcc ttgatagaaa aaatggaaaa acgaatggaa
     3301 atgctggaca accgctgcag gcaggaaggc aaacgcctgt ttgaggcccg ctattacggt
     3361 tccgccgcct taaaggacat tttggaaaat tcggatgaat tcagcgacct ggtagaaccg
     3421 gatgaagacg gggcgccccc cggtgcactc cgggaaaatg aagaggccgg acagtagccc
     3481 cccgccccgt ttctcccccc tcttttttca ttcccggcac gccccttccc cgtatgggtt
     3541 cctgcgcggc caagtccatt tcaagcttgc cggaaccgtg aaaaacgggt ttactgtggg
     3601 cagcatgcaa aagttagcag gtaaaacagc catcgttacc ggcgcgggcc gcggaatcgg
     3661 caatgccgtc gcgcgccgct tcgcttcgga aggagccagg gtcatcctga tcagccgcag
     3721 tccatccagc tgcggggggg ccgcagaaga aatcaacaag gaatttccgg attcctgcaa
     3781 ggcctacccc tgcgacgtag cggattacgc ggccgttcag gaaaccatgg ccgccatttt
     3841 gaaagacttc ccgcagattg acatcctggt gaacaacgcc ggcatcacgc gggactccct
     3901 gatgctccgc atgaaagagg aagactggga tgccgttctg gacaccaacc tgaaaagcgc
     3961 gttcaatacg gtcaaggccc tccagcgcgt tctcatgaaa tccccggccg ggcgcatcat
     4021 caacatgagc tccgtcatcg gtctcgtcgg caacatcggt caggccaatt acgccgcttc
     4081 caaggcgggc ctcatcggtt tcaccaaatc actggctcag gaattcgctc cgcgcaaagt
     4141 cacgtgcaac gccattgctc ccggcttcat ctccacggaa atgtccaatg ccattcccga
     4201 caatctcaag gaagaaatcg ttaagaaaat acctttgaaa gaacaaggtt ccgtggaaga
     4261 tatcgccgcc ctgacggcct tccttgcctc tgacgatgcc cgttacatca ccgggcaggt
     4321 cattgcctgc gacggaggca tgacgatgta gggcattccg gttttctcca ttccatgcgc
     4381 ggcattttcc ttgtttcctg ctttctggga ggaagcgccc tgctggccgg gtgccgggaa
     4441 gaaaataatt ccccccgccc ggccacggaa gatgccgcgc gcattaccag cgcacgccag
     4501 tggggagaaa gccgatccgc gctgcaaaaa cgggaactgg accgcgctgc cggtcctgcc
     4561 cttcccattc cggatgacct gccgtcccgg gagctggtcg gcacaacgcg ccaaatccat
     4621 cagctcattg aagcttccgg aaatccggca cgttttgaat cctacacgga aacggttccc
     4681 gtggcggaag cttccctgcg catggtcgcc ataccgggag gaacgttcct catggggagt
     4741 cccgcggaag agccgcaccg gaaaccggac gaaggtccgc agcataaagt gagcatctcc
     4801 cccttctgga tctcggaaac ggaaatcccc tgggaacttt atacggcctt catggaaaac
     4861 gggcgtccgc gcgccaagga cggccagctt ctggaggaac agccggatga cgaactgtgg
     4921 gactccgtta cgcagcctac cgccccctac accgccatga acctgggcat gggccacggc
     4981 tatgaacacg gtctgcccgc catctccatg tcccaccacg ccgccagcaa attctgcgaa
     5041 tggctgagcg cccagaccgg gcattactac cgcctgccca cggaggcgga atgggaatac
     5101 gcctgccggg ccggctcccc cggcgcctat tcttacggaa acggggaagc ctctctggac
     5161 cagtacgcct ggtactggaa caactccaat gaccgctacc agaaaacagg ctctaaaaaa
     5221 ccaaataagt ggggactccg ggacatgcac ggaaatgtgg cggaatgggt tttggactct
     5281 tacgttccgg atgcctacgg caaacggagc ggcttgcccg cgaaagaccc cttggtcatc
     5341 atccccagcg cccctcacat cgttcgcggc ggttcgtggg aagacgaccc ggacagcctg
     5401 agaagcgctg cgcgccgcgc cagcaccccc gcctggaacc gtcaggatcc tcaaaaccct
     5461 aaaagcatct ggtacctgac ggacggaggc atgatcgggt tccgcgtggt gcgccccatg
     5521 aacattccgg acattatgac gatgcaccgc ctctggaatt tctccaaggg ggagccgtaa
     5581 agaacaacct ttcatgacca ttgcattaag aacggaacaa tcctcagacc atgccgaaac
     5641 ggaacatgtc acgagagaag cgttctggaa ctatttcgtc cccggctgcc atgaacatta
     5701 cctgctccat atcatgcgcg tcagtccgtc cttcatcccg gagctggatg cagtcgccgt
     5761 ccacggcagc cgcatcgtcg ggaaacatcg ttgatgcaac gtccgtcatc agggcagacg
     5821 atggaaaaga atatgaagtg ctgggcatgg ggcccattgc cgttcttccg aaataccagc
     5881 gccggggaat aggacggcga ataatatgta tgcggcggcc ctccaggtct gtgagctgca
     5941 aaggggttcc ctatccggcc tgaaaggcca ctatgtgaaa gctgccgtgt accatatgga
     6001 cgaaaagcgc gctgccgaat ttgacggcat ttcccggtaa agaaaaagct ttccggtact
     6061 gcgtctcaaa aacgtttcca gcaaattgcc gccatgccga aaaaaccgga tacggccccc
     6121 tgcccccgga aattccgtac cttccggagg gcatgaatcc cgcatacgga taagcaattc
     6181 ttcctctctg gatataaaaa acaagagctg ttccgcaaga acagctctca tccgccgatt
     6241 tttcgccatc aggaagctca agccctgagg cggcgcatca tcagcgcggc cagtcccagc
     6301 aggcccaggg aaaccgtggc tggttccggc accatttccc ctcggatttc cgtgaaaatc
     6361 ggggataata agctgaaagt attggttccg ttggctcccg taataacgac agaatcacca
     6421 ggcgctccct cggcgtcata atggccgcgg atgccgggag cagtcaatcc gccgctgatc
     6481 gttacggtat ctccttccgt gttagcagta ggggcggctg ttccccccgc agcatataaa
     6541 tacgttttag acgtatcctg catcaagtcc atcacggact ggctcacggc caggaaacgg
     6601 tatgtcaatg ccgcgtcaag aagcagggga gaaccatcca gggaagaaaa actgaacgtc
     6661 agattaatcc ctgctgcagt agttcccgta ttggtgctcc agccgatgac cgaattgtcg
     6721 gagccattca gcaccaggaa gccgtaagtg acattagcgc ccaaattgtt ggcggctccg
     6781 cgcagcgtaa aactgtccag tctgatctct ccggacaggg aggagggaga agaggaatcg
     6841 gaaggagcca gggaagaaga ccccaggcca agataaaacc catggatggt actattgtaa
     6901 ttatccgtac cgggagtgta ataattaaaa acggtcgctg cctccgagga aacagcaaag
     6961 cttcccatcg cgattaaaaa tgtcagtgtt ttcttcatat ttattattcc ttttggatgg
     7021 caacttgtag cgaatttgga attccccaat cggatttgga atccgtcaag taatgaaaaa
     7081 gaggccaaat caatcatgaa accaatgaat aacaaagatt gccccgtcat cttgacaaaa
     7141 ggaccagaga tattaaaaaa tcattatttt caatgaatta taaatacaat atactaactc
     7201 ttaatatttt taattgcttg cggattccaa attcgttatt caagcgcaag tgcatacatt
     7261 gaatcttgca tcattttatt aagatactga ccatgaagaa attattatcc accctgattc
     7321 tttcggccgg catgagcctg agcgccaccg cgaataccac tctgctggat agctctatcg
     7381 tgggatattc ggactttacc tcccaaacgg cggatttcgg caccctgaaa gattccgttt
     7441 ccatcacgtc tgacgacagc aatctgacgt tatccgggat aaccttcaac ggatacggta
     7501 ccaacaaccg cgacgttatg tctgtgacaa tggttcttga tctgtccaaa atcaacactc
     7561 cggagaccta taccgctctg tttaacgcca aaaacagcag tgtaagctgg ggcgtgggcc
     7621 tgaacacgga ccggaaactc cagggattat ggaacaacac ctcatacagc gggcccgtcg
     7681 ttgacacccc gctgggcatg gaagggtccc tgaccatttc cgtagtcacc ggagatcttg
     7741 gcacccgcat ctattttggc gacagcgcta cgtactattc caacagcggc ctgaaattcg
     7801 gcaaccagca aattgatcag attctcatgg acgcaggact ggctgaatcc atcgaacagc
     7861 tctacatcca cgactccctc ctttcccagg aacaagttgg tcaactgatg agtgaaatcg
     7921 ccagcattcc ggaacccgcc acggcttccc tgggcctgct gggactggcc gcgctgatgn
     7981 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     8041 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnttttcctt atccgttcaa acatctgccg
     8101 aaaaaacaga ggggaaaagc ttccatttgc tgcggcaacc tcacggccag cacttgacgg
     8161 aaaaatagca ttcagtctcc cccggtaggg tcatttcaag agcttccggc cccgccccac
     8221 ttccgtacac gccccttttt cccatgccgg gacagccgga accggagcat gcaaagcccg
     8281 gcttccctca gcatccggaa cagcccatcc tttcagcaat ccatttcccc gcacggtccg
     8341 gatcgctgcg gttccgtccg tcggcaacag actccttccc cgaaacaggg aaaaggagtg
     8401 ggaaaatggc tgagcttgaa cctttatccc ccgttcccgt ccatgaacct tcaaaaacag
     8461 cagctgctac tgcgcctgtt ccggtatttc aaaagcagaa aaggagaacc gcgttttttc
     8521 aacaaacgga atatatgcct tctggccgcc gccggcgcct acatcctgac tcccgacgaa
     8581 ttcctgtttg acggaatcgg caggctgggc cttctggatg acgcggcggt catcctgggc
     8641 gccgtcctca ccgtcttttt cccggacggg gactagaggg ccgtaccctc cgccgcgcct
     8701 cgggcggaat tagcgggacg acactttccg gaacttcggg gactgtccca tgaatgtctc
     8761 cggattttcc aggagaagac gttccgtttc ctgccgggaa aaaccgcgcc tgcgcagctc
     8821 gcaggccagg gccgtcagcg ccaggggatc ggaatccccc cagtccgccg cggaattggc
     8881 ccagacacgg tccattccgt acaattccag aatatccgcc gcccgcttgg gattcagctt
     8941 actggtggga taaagggtca gcccggccca gtaaccggcc tccttcacca gcgggaaggt
     9001 atgttcctca cagtgatcca ccagcacgcg gcaagggtcc agatccggac ggtttttcag
     9061 ggcggaaaga atcattacgg tccccttaag cttgtcttcc agatggggag tgtgaatcag
     9121 cacaagctgg ttgaggcgca ccgccagatc cagatgctct tcaaaaatag tcatttcatg
     9181 ggaagtattc cggttcagcc ctatttcccc gatgccgagg acattgggcc ggtcaatgaa
     9241 ctccggaatc agtttcatca catcccgcgc gaaagccacg tcctgcgcct ccttgggatt
     9301 gatgcacagc catgtgtaat ggtccatgcc gaacttggcc gccctggcgg gttcgcattc
     9361 cgtaagctgt acgaaataat cccggaaacc gtccgcggac gaacggtcgt aaccggccca
     9421 gaacgccggt tcccctaccg ccaggcagcc ggcctgcgcc atggcccggt attcgtccgt
     9481 ggtgcggcac accatatgta tatgaggttc tatgaaagcc atcattctta tttgctgagg
     9541 ttcggggctc cgcaggccgc tttggctgcg gcggtttccg gcacggtgtc atccctgtag
     9601 gaaagggctt ccagaatggc ccggacgcgt ccggggccgg atgcggacaa gaggggaaga
     9661 acatccatca gggcatggta gcggaaatcc gcctcccctt ccccgcggtc cacccggtcc
     9721 agaaatgcgg ccacatccag aacgccggcg cgcgccgctg cgaaatccgc gtccagcacc
     9781 tcctttttac ttcttttcat gcacagacga tacgcctatg cggaaagcct cgtcaagccg
     9841 gaacaggcaa caaaatgata accattccaa actgataaac agcaacctct ttccccggtt
     9901 tttcaaaaat ccgaaaagcg ccggaaattc aagaagaggc ttgccatccg ggcttgaacc
     9961 gggcatcctg tgaagacgca tttatttcat tagagcgcct atgaatgcac tagtaaaaac
    10021 catatgtaca ttcgtgacat cctccatcgg ccgcaaaatc attgtggctc tgacggggtt
    10081 atgtttggtc ttgttccttg cgggacacct ggcaggcaac cttctcatct tcggaggccc
    10141 tgaatggatc aacacctacg cccacggcct gcactccatg ccggaagcag ccctctgggg
    10201 aatccgcgcg gggcttgcgg tgatcttcat catccacgtc tggctgacca tccagctgaa
    10261 gctggaaaac catgcggccc gcgaacccta cgtgttcaag aacaccatta aggcaacgct
    10321 ctcctcccgc tacatgatct ataccggttt gaccgtcctg gtgttcctga tctaccacct
    10381 gtaccagtac accctgcgcg tgggatacga ccccgcccag ttcaccacct ttatttccga
    10441 cggtacggtg gaaacctttg acgtgtacaa gatgatcgtg accggattct ccaacgtatg
    10501 gtgctccgcc ttctacatcc tggccgttct gatgctgttc agccatctac gccacggggt
    10561 acagtccatc ttccagactg tgggcgtcga ttcccgcaaa atccggccct tctacaactt
    10621 tatcgccatc gcctacggcg cgattatctg cctgggcttc atctccgtgc cggtctcggt
    10681 tcttctgggt atcatcaaat aaccatcaac tcctctcaaa gtcatgatta attttcccgt
    10741 aagcgactgg atgccggatg ccaaaattcc ctccggccct attcaggaca aatggtccaa
    10801 gtacaaactt gagtccaaac tgatcaatcc gaacaacaag cgcaagtaca cggtgcttgt
    10861 ggtaggttcc ggcctggctg gcgcctccgc tgccgccacg cttgccgaac ttggctacaa
    10921 cgtcaaatgc ttctgctacc aggacagccc ccgccgcgcc cactccattg cggcccaggg
    10981 cggcattaac gcagccaaga actaccagaa cgacggcgac tccgtttacc gcctgtttta
    11041 cgacaccgtt aaaggcggcg acttccgcgc ccgtgaagcc aatgtctacc gtctggcgga
    11101 agtctcctcc aacatcattg accagtgtgt ggcccagggc gttcccttcg gctggacaac
    11161 cgctccttcg gcggcgccca gctcaagcga accttctacg cacgcggaca gacgggccag
    11221 cagctcctgc tgggtgccta ccaggccctg gaaaaggaag tggccaaggg acacattgaa
    11281 atgttctccc gccatgaaat gatggatctg gtgctggtgg acggcgaagc caagggcatc
    11341 gtcacccgca atctggttac cggcgaaatc aaatcctacg caggggatac cgtcctgctc
    11401 tgcacgggcg gctacggcaa cgtgttcttc ctgtccacca acgcgatggg ctgcaacgtc
    11461 actgccgcct acaaggccta caagcgcggt gccttcttcg ccaacccctg cttcacgcaa
    11521 atccacccca cctgcattcc ggtcaagggc gactaccagt ccaaactgac gctgatgtcg
    11581 gaatccctcc gcaacagtgg ccgcatctgg gtgcccaagt cccgtgaaac cgcagaaaaa
    11641 atccgtaaaa aggaaatcaa gccttccgat gttcccgaag aagaacggga ctactacctg
    11701 gaacgcaagt atccctcctt cggcaacctg gctccgcgcg acatttcctc ccgcgccgcc
    11761 aaggaagcct gcgacgacgg ccgcggcgtg gccgtcaccg gcaagggcgt cttcctggat
    11821 tttgcggatg aaatcaagcg catgggccgc gaatggattg acggccaata cggcaatctg
    11881 tttgacatgt acgaagaaat cacggacgac gacccccatg aaacgcccat gatgatctac
    11941 cccgcctccc actacaccat gggcggcctg tgggtggact acaacctcat gtccaacgtg
    12001 aaggggctgc acgtcctcgg tgaagccaac ttctccgacc acggcgccaa ccgcctggga
    12061 gcctccgccc tgatgcaggg cctgtctgac ggctacttcg tcattcccgc cacgttgccc
    12121 gcttacctga cgaccaccaa gcccggcgcc gtcaccaccg ccgccccgga attcaaggct
    12181 gcggaagacg aagtgaagga acgcatcaac aagctcctga atgtgaaggg caccaagacg
    12241 gtggactcct tccaccggga actgggcctc atcatgtggg aagactgcgg catggcccgc
    12301 acggaagaaa gcctgaccca cgccattgaa cgcattcccc agctccgcaa ggaattctgg
    12361 gaaaacgtgc gcgtaaccgg cacggcggac ggcatcaacg cggaactgga aaaagcctgc
    12421 cgcgtggccg acttcctgga attcgcccag ctgctctgct atgacgccct gaaccgccag
    12481 gaatcctgcg gcgcccactt ccgcgtggaa taccagctgc cggacggcga agccaagcgc
    12541 aacgacgatg aatacgccta tgtagccgcc tgggaataca ctggcgtgga cagcctgcct
    12601 gttctccaca aggaaccgct gaccttcgag aacgtgcacc ttgccatccg cagctacaag
    12661 taaagatagc caatacatta acactcaaaa gaaagattat aacatggcta aaacactcaa
    12721 tctcactctc aaggtctggc gccaggaaaa ccgggaagcc aagggccgca ttgagaccta
    12781 tgccgccaag gacattccgg tggacgcctc cttcctggaa atgctggaca tcgtcaatga
    12841 aggcctggtc aaggaaggca aggaacccat ccattttgac cacgactgcc gggaaggcat
    12901 ctgcggcatg tgctccctga ccatcaacgg cattccccac gggccggaac gccaggtgac
    12961 cacttgccag cttcacatgc gcaagttcaa ggacggcgat accgtctgga ttgaaccctt
    13021 ccgcgcgaag gctttcccaa tcctgcggga cctgatggtg gaccgctccg ccctggaccg
    13081 catcatcgcc gccggaggct atattgacgt gcgtaccggt tccgcgccga acgccaacaa
    13141 catcgccgtg gaaaaagtga aggcggacgc cgcctttgac gnnnnnnnnn nnnnnngcgc
    13201 ctgcgtggcc tcctgtaaaa acgcttccgc catgctgttc acctccgcca agatcgccca
    13261 tctcaatctg ctgccgcagg gccagccgga acgttccaag cgcgtcctgg ccatgatgaa
    13321 gcagatggaa gcggaaggct ttggcaactg cacgaaccag tatgaatgtg aagccgcctg
    13381 cccgaaaggc atcagcgtgg acaacatcgc ccgcctcaac cgcgacttca tgcgggccaa
    13441 cgccaaggaa ggcctctgtt tctaaagaag attccttctt aagacgctct gtaaaaactc
    13501 ccggcggcat cggctgtcgg gagttttttc attaccagat ttccttgaac caggaataaa
    13561 ataccagaca gttgcttcct catcgtcgcg cagcgtaaaa aattgttaca ccggaaggca
    13621 cccagtaatc caggaaaccg tacttggaaa tgccggacga aacctaagca ggccccgtcc
    13681 gacagcgacg gccccatctt tcttcgagag agaaaaacat tgattacagg aattagactg
    13741 atgcccggaa gggatggcct cctgtcaagg gctcagcatg agaggaaaac attttctaac
    13801 aaacagacaa cattgatgtc tattaaggga atgcactgag cgtaagaatt ataatattat
    13861 tttctcatgg aataaattct catgttctta aaataacaga aattttcaaa taaattctta
    13921 ttgacgctaa atctgaataa tgctactatg aaaataataa tagagggttg ttctcttcta
    13981 atttcattat caatactaac tcttaatacc tgatgaatcc gcctcatcgt tctgccgttc
    14041 ccggctaccg gaaatggtac tttggagccg gcggcagccc cggcaggcgg ggcatggagg
    14101 cagctccgga gcccgatccg ctgccgtttg aagcgatccg gatccatgag gaaaggaacg
    14161 tggggccgcc gagcacgtcg gcggacggat acagcgcgca cgggacattc accatcccgg
    14221 aaggagcgga gggcaaaaag ctctacgg
//
