LOCUS       c00267_gnlPro..         4442 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IJEMKAAN_267.
ACCESSION   c00267_gnlPro..
VERSION     c00267_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 14:39:01
            Original ID  :: gnl|Prokka|IJEMKAAN_267
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4442
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4442
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1190:4440]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1191..4440
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..4442
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4442
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             3..449
                     /locus_tag="ctg267_1"
                     /transl_table=11
                     /translation="LFPSLMLPPVATPPEHVPNLLYAFSANIGQVMFQGNMLTGLFLLF
                     AILLNSRLNAAYTIWGALLPLGMILLPATSIADFNMGLLGYNGVLCAIAAGNHLSIRSL
                     IRATLAILLSIGLQIGGMRLGITTLTAPFVLSVWITNLIIKDKE"
     CDS             547..783
                     /locus_tag="ctg267_2"
                     /transl_table=11
                     /translation="MTKLSNIPVKETAAKAARTRKAKTAPTAPQWDPTRPIQFTQEEIW
                     EHIHEIEKGPFLTLDEGFKRFEAWKQDLLKSRL"
     CDS             750..1091
                     /locus_tag="ctg267_3"
                     /transl_table=11
                     /translation="MEARPTQKQVITSSSFWESYDNVYVQGLDLFGFYQAELYANKIKA
                     ILYELDRTYPYYPECRHLTTKSRMYRNIILDSHLIIYRITEERIEVLDIVHSASSMRKI
                     KKTRNIHIE"
     CDS             complement(1191..2234)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg267_4"
                     /sec_met_domain="IlvN (E-value: 8.8e-48, bitscore: 150.9,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.5e-40, bitscore: 127.8,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQMNFGGVVENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRQGKTYEKAVEDGWVPGETLFGIEEACDKATIIMCLLSDAAVMS
                     VWPTMKPYLTAGKALYFSHGFAITWNDRTGVVPPADIDVIMVAPKGSGTSLRSMFLEGR
                     GLNSSFAIYQDATGKAMDRTLALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMG
                     PFHDAIKPVVEKLYANVKCGNEAQISIDSNSKPDYREKLEAELKALRESEMWQTAVTVR
                     KLRPENN"
     CDS             complement(2284..3009)
                     /locus_tag="ctg267_5"
                     /transl_table=11
                     /translation="MEKVGLFHFVAEPYLMDFRGRVTLPMIGNYLIHAASSHAGERGFG
                     FNDMSERHTAWVLSRLAIEMKEYPTAFDKINLYTWIDEVGRLFTSRCFELADENGKTFG
                     FARSIWAAIDVETRRPTLLDIEALGKYIDERPCPIEKPGKIMPAENKAEGIPYSIKYSD
                     LDINGHFNSVKYIEHLLDLFDIDQFKTREIGRLEIAYQSEGKQGMPLMLHKAESAPDKQ
                     DMAICHEGKAICRAAVTWR"
     CDS             complement(3016..3570)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg267_6"
                     /sec_met_domain="ALS_ss_C (E-value: 8.5e-18, bitscore:
                     53.4, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKKLYTVIIFSENIVGLLNQITIIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDMIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEGLIRKYNARILEMNETCVVLEKSGHYDETQALFNELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLADMERKLHEKQQ"
     CDS             complement(3586..4440)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg267_7"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.1e-51, bitscore:
                     163.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="FDDRVTGDLKTYAKQAKIIHLDIDNSEIGKNVAVDVKVLGNAKHT
                     IPMITALLEERKRPEWNAEFDRDEKEEYDKVIEKELYPTEGQLKMGEVVRKVSEATGND
                     AVLVTDVGQNQMMGVRYFKYKQTRSVVTSGGLGTMGFGLPAAMGAKFGAPDRTVCFFTG
                     DGGMQMTIQELGTIMQEKLNVKIIILNNNFLGMVRQWQELFFHERYSNTIMENPDFVAI
                     AKAYGIAGRAVEKREELDDAIAEMLNHDGAYVLVANVETCGMVYPMVPAGGSVTNMIMG
                     DEK"
ORIGIN
        1 atctattccc ttcgttgatg ctcccacctg tagcgactcc tcccgaacat gtcccaaatt
       61 tactttatgc tttcagcgct aacatcggac aagtgatgtt tcaaggcaat atgttaacag
      121 ggctattcct tcttttcgcc atcttattaa actcacgctt aaacgcagcc tacacaatat
      181 ggggcgcatt gctgccattg ggaatgatat tactaccagc gacaagcatt gctgatttta
      241 acatggggtt gctcggctac aacggtgtat tatgcgctat cgcagcaggc aaccatcttt
      301 ctatccgtag cctgatacgg gcaaccttgg cgatcttact atctatcgga ttacagattg
      361 gcggcatgcg tctggggatc acgaccctta ccgccccttt cgtactctcc gtatggataa
      421 caaaccttat aataaaggat aaggaataat tccagcgtca tccgcaaacc attatccctt
      481 attaactatt aattaccaac tatattccgt acatttgccc cacacgaatt aataaggatt
      541 acgactatga cgaaattaag taacatcccc gtaaaagaaa cagcggccaa ggccgcaagg
      601 acacgcaagg ccaaaaccgc cccgaccgcc ccccaatggg atcccacccg ccccatccaa
      661 ttcacccaag aggagatatg ggaacatatc catgagattg agaaggggcc gttcctaacc
      721 ctggatgaag gttttaaacg ttttgaggca tggaagcaag acctactcaa aagcaggtta
      781 taaccagtag ctcattttgg gagagttatg ataatgtata tgttcaaggc cttgacttat
      841 ttggattcta ccaagcggaa ttatacgcta acaagataaa agccatctta tacgagttag
      901 accgaacgta tccttattat cccgaatgcc ggcacctaac tacgaaaagc cgtatgtacc
      961 ggaacatcat cttggattca caccttatca tctaccgcat caccgaggaa cgcatcgagg
     1021 tgctggacat cgtccattcc gcatccagta tgcggaagat caagaagaca aggaatatcc
     1081 acatcgaatg acataaagca aggcgagcca cccacaagtg acccgcctct atcaatcaac
     1141 aattaaatac tatcctaatt ttcaattctc aattctccat tttcaattat tcagttgttc
     1201 tccggacgaa gcttgcgtac agtaacagct gtctgccaca tctcgctctc gcgcaatgcc
     1261 ttcaattcag cctccaattt ctcacgataa tccggcttag agtttgagtc gatagagatc
     1321 tgagcctcgt taccgcattt tacgttcgcg tacaatttct cgacaaccgg cttgattgcg
     1381 tcgtggaacg gacccatcca gtccaaagcg ccacgctggg cagtcgtaga gcagttagcg
     1441 tacatccagt ccataccatt cttggcgaat aagggcatca aggattgagt caactcctcg
     1501 accgtctcgt tgaaagcctc ggaaggagta tgtccattct cgcgcaatac ctcatactgg
     1561 gccaacaaca aaccttggat agcgcccatc aaagaaccac gctcaccagt caaatcggaa
     1621 gtagcctcac ggatgaaagt cgtctcaaac aaataaccgg aaccgatacc gatacccaac
     1681 gccaacgtac gatccatcgc cttgccagta gcgtcttgat agatagcgaa agaagagttc
     1741 aagccacgac cctcaaggaa catggaacgc aaagacgtac cagacccctt cggagcgacc
     1801 atgatcacgt caatatccgc gggaggaaca acgcccgtac gatcgttcca agtgatcgcg
     1861 aaaccatgag agaaatacag ggccttgcca gctgtcagat aaggcttcat cgtaggccat
     1921 acagacatta cggcagcgtc ggacaacaag cacatgatga tcgtggcctt gtcgcaagcc
     1981 tcctcgatac cgaacagagt ctcacccgga acccatccgt cctcaaccgc tttctcgtaa
     2041 gtcttacctt ggcgctggcc aacgattacg ttgaagccat tgtcacgaag gttcaatgac
     2101 tgtcccggtc cctgtacgcc atagccgata acagcgattg tctcatcttt taatatctct
     2161 cttgcctttt ccaacggaaa ttcctcgcgg gtcattacat tctctacaac accgccaaaa
     2221 ttcatttgtg ccattttctt tttaactatt aatgtttaaa aacctattta tgtatctctt
     2281 ttattatctc caagtaaccg ccgcacgaca gatcgccttt ccctcatggc aaatagccat
     2341 gtcttgctta tcgggagcgg actccgcctt atgaagcata agcggcatac cttgtttacc
     2401 ctcggattgg taggcgatct ccagacggcc gatctcacgg gtcttgaact ggtcgatatc
     2461 gaacaaatcc agcaggtgct cgatatactt cacgctattg aagtgaccgt tgatatccaa
     2521 gtcgctgtat ttgatcgaat acgggattcc ctccgcctta ttctccgccg gcatgatctt
     2581 gcccggcttc tcgatcgggc acggacgctc gtcgatatat ttgcccaatg cctctatatc
     2641 caataaggta ggacggcggg tctccacgtc gatagccgcc caaatagaac gggcgaatcc
     2701 aaaggttttc ccattctcat ccgccagctc gaaacaacga ctggtgaaga ggcgtccgac
     2761 ctcatcgatc caagtgtata gattaatctt atcgaaggcg gtaggatatt ccttcatctc
     2821 gatagccaga cgggacaaca cccaagccgt atgacgctcc gacatatcat tgaaaccgaa
     2881 cccacgctct ccggcatggc tggaagcggc gtgaatcaaa tagttaccaa tcatagggag
     2941 cgttacacgt cccctgaaat ccatcaaata cggctccgcc acaaaatgaa ataatcctac
     3001 tttctccata tcttattatt gttgcttttc atgtaacttt cgctccatat cggccaacat
     3061 atcgctcaag cgctccacct tgctcttcgt gatagccaca cgtccggagc ggatgaattg
     3121 caggacaccg atcgtctcgc tcaactcatt gaacaaggct tgtgtctcgt catagtggcc
     3181 actcttctcc aataccacgc aggtctcgtt catctccaag atacgagcgt tgtatttacg
     3241 gatcaatccc tccacggttc ccatcttgat gaaaagctcg gtacttagct tataaagggc
     3301 gatctcttga taaaccagat cctcatccgt attataataa gccttcaaga tatccacacg
     3361 tttatcgatc tgtttcacca ccttatcgat catatcctca tcggcgaatg tcgtgatcgt
     3421 aaacttatgg atgcccttga tagcggacgg agagacggac agagtctcga tgttcagctg
     3481 tcggcgtgta aagataatcg ttatctggtt caaaagacct acgatattct ctgaaaagat
     3541 aataacggta tataatttct ttgttgtcat agcttcatct cctccttatt tctcgtctcc
     3601 cataatcatg tttgtcacgc ttcccccggc aggaaccatc ggatatacca ttccgcaagt
     3661 ctccacgtta gcgaccaaca cgtaagcgcc gtcgtggttt agcatctcag cgatagcgtc
     3721 gtccaattcc tcccgctttt caacggcacg gccggcgata ccataggctt tagcgatcgc
     3781 cacgaaatcc ggattctcca tgatggtgtt tgaataacgc tcgtggaaga acaattcttg
     3841 ccactgacgt accataccta agaagttatt attaagaatg ataatcttca cgttcagttt
     3901 ctcctgcatg atagtgccca attcctgaat cgtcatctgc atacccccat caccggtaaa
     3961 gaagcagacc gtacgatccg gagctccgaa cttagcgccc atagcggccg gcagaccaaa
     4021 tcccatcgta cctaaaccac cggaagtcac cacgctacgg gtttgtttat atttgaaata
     4081 gcggacgccc atcatctggt tctgcccaac gtcggtcacc aatacagcgt cgttaccggt
     4141 cgcctcggaa accttacgga ctacctcgcc cattttcagt tgaccctcgg tcggatacaa
     4201 ttccttctcg attaccttat cgtattcctc tttctcgtcc cgatcgaact cggcattcca
     4261 ttccgggcgt ttacgttctt ccaacaacgc cgtgatcatc ggtatcgtgt gcttggcatt
     4321 ccccagcacc tttacgtcca cggcaacatt cttgccgatt tccgagttgt cgatatccag
     4381 atggataatc ttggcttgct tagcgtatgt ctttaaatcg ccagtcacac ggtcgtcgaa
     4441 ac
//
