LOCUS       c00007_gnlPro..        16315 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OBNJCLLE_7.
ACCESSION   c00007_gnlPro..
VERSION     c00007_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 08:43:10
            Original ID  :: gnl|Prokka|OBNJCLLE_7
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16315
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16315
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3339:6315]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3340..6315
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..16315
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16315
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             complement(2..709)
                     /locus_tag="ctg7_1"
                     /transl_table=11
                     /translation="MRFTRLILALTSFLILITQTDLFASTVLHKTSMVDLSNNAIICMH
                     QDPDGYLWIGTYDGLNLYNGKDTYVYRFELNNKNSLCSNIIHKISDAEPGFLWISTSLG
                     INKFSLKERKVTESFPGYMECDLLASDSSGITLAICKENRISCYTPSSDGFRDLPREGV
                     GPQTVRTLFAGTDGHFYLLLASGILKKLTPDFSDTTFNLLSEERQFHNKPILSAFYENN
                     HIFIVRSEERRVGK"
     CDS             866..3169
                     /locus_tag="ctg7_2"
                     /transl_table=11
                     /translation="MEQCEENSQENDDVIIEKEISKLIEEQRLFTESIYACLPVGIEIY
                     DAHGVLRSINDHALRMYGVDDRTSVVNIVNLYKSPFVDSELLARIQSGEDISLEFEYDF
                     DRVNKDAYYSSHNKDTMIYGVKVIPIWSRKKHLIGHILLANDMTSVKEVEFRTEESKKN
                     LEMAMKAANMASWVYDVNKKVFNPLYGLTVAKKNMPMEAVLDILHPQDRAPLIRLFSQL
                     IGNEIEQGQMTLRFYNEQEEMYRYYESRMRLSTEHRGKLQIIGTQMDITERLQMAKKAQ
                     DLIAKRDLAMKVSNIVHWDFDVNSQKFESYNDPINDYVSDRLLTVSEYMDVIYPEDRSV
                     FYDAMQSLIAGKNVTINFTCRIQTKYDETWQYCDFMGVPFDQDENGDIIRYTGFRQNIP
                     KIQQLNRELKERNYKIELSFKTVGMSYWDFDVKSLKFSAFNDPINDFYSEKTITPEDYL
                     NATHPDDVVFVRKYMEHMFRGIDKDFNVKYRSKTKWDDEWQTLLVTGIQVERDKEGHVT
                     RYTGITINNTKWEKMIQQLKELKEKAELSDRLKSAFLANMSHEIRTPLNAIVGFSELMV
                     TCDDPEEKKEYINIIQSNNELLLRLINDILDLSKIESGIIERRKENFNLAKVCNELFVT
                     IQAKMTNPNVELRLDGPNSECWVLLDRNRLKQVWMNFLTNAVKCTKSGYIKMGYGIERK
                     GLRIYVEDTGIGIPDDLHDKVFTRFEKLNEFSQGTGLGLTISRAIVEAAGGEVGFTSKL
                     GVGSTFWAWLPLRP"
     CDS             3340..5580
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_3"
                     /sec_met_domain="Gly_radical (E-value: 5e-46, bitscore:
                     145.5, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 3.6e-282, bitscore:
                     926.8, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKFENECWDHFKGETWKREINVRDFIQSNYTPYEGDDSFLVASSE
                     KTRKVWNKLTEMFKVEREKGIYDAETKLPQGIDVYGPGYIDKENEVIVGLQTDAPLKRG
                     IFPKGGIRMVENSLEAYGYHLDPMTKEIFTKYRKTHNEGVFSAYTEEMIAARRSAIITG
                     LPDAYGRGRIIGDYRRVALYGTAILIEEKKRFLNRLDIQEITEEIIQSREEISEQIKAL
                     KAFEKMCASYGFDVTRPAQNAREAVQFVYLAYLAAVKDQDGAAMSIGRTSTFLDIYIEK
                     DIREGKLTEEEAQELVDQLIIKLRIVRFLRTPEYNDLFSGDPVWVTESLGGQGVDGRSL
                     VTRTSYRYLHTLYNLGPAPEPNLTVLWFKNAPENWKRFCAKVSIDTSAIQYENDDLMRP
                     DYGDDYGIACCVSPMKIGKQMQFFGARANLAKCLLYAINGGRDERSGVQVAPMFEPVRG
                     EYLEYDEVMAKYEQMMRWLAKVYVNALKIIHYMHDKYAYEAFEMSLHDGDVERIRATGI
                     AGLSIVADSLAAIRDTKVRVIRDERGLAVDFEREGEYVPFGNNDDRTDSIAVEITEKFM
                     EYLRQHETYRHAKPTQSILTITSNVVYGKKTGTTPDGRIGGTPFAPGANPMNGRDTKGA
                     IAALASVAKLPFQHAHDGISYTFAVSPATLGKEREVQINNLVSLLDGYFTPDGGQHLNV
                     NVFDKDLLIDAMEHPEKYPQLTIRVSGYAVNFVKLTREQQLDVISRTINHSL"
     CDS             5581..6315
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 67.6;
                     E-value: 4.7e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_4"
                     /sec_met_domain="Radical_SAM (E-value: 1.7e-33, bitscore:
                     106.2, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VIKGKIHSLESFGTVDGPGIRFVVFMQGCPLRCLYCHNPDTWNPK
                     GKVKYQMTPGELLTEVLRYKSFIARGGVTVTGGEPLLQPEFLKEFFRLCQEQGLHTALD
                     TSGFVCTSKAWEVLDYADLVLLDIKTLNPDLHPLLAGVKQDNTLLFLDELERRGIDTWI
                     RHVIVPGYTDNDEWLEALARYVSSYKVVRKVELLPYHTMGTYKYEQLGLDYPLKGVEPL
                     SKERLDNAKAIFSRYKPENNKA"
     CDS             6514..7092
                     /locus_tag="ctg7_5"
                     /transl_table=11
                     /translation="MKTPQEIAEMISKRFYPLPDADLDSLASIIESSKAAKGKLLLDNG
                     QISKYLYYVESGLLRQFYYKNKRDITEHFSCEGNIVICIASTFQREPTRLLIEALEPTV
                     YHRISFSEFSDLLKTSLAINRLYQKILEWALMLSQEKADSWRFESARKRYLRFQQEYPE
                     VAKRASVNHIASYLLMTPESLSRVRAGVL"
     CDS             7200..8480
                     /locus_tag="ctg7_6"
                     /transl_table=11
                     /translation="MKIEKITGREILDSRGNPTVEVDILLESGVMGRASVPSGASTGEN
                     EALELRDGDKKRYGGKGVLKAVENINTIIAPALKGMSALDQIGIDHAMLALDGTKTKSK
                     LGANAILGVSLAVAKAAANYLDIPLYRYIGGTNTYVMPVPMMNIINGGSHSDAPIAFQE
                     FMIRPVGAASFKEGLRMGAEVFHALKKVLHDRGLSTAVGDEGGFAPNLEGTEDALNSII
                     VAIKAAGYEPGKDVMIGMDCASSEFYKDGIYDYTKFEGEKGVKRTSDEQVDYLEKLINE
                     YPIDSIEDGMSENDWAGWKKLTDRIGNHCQLVGDDLFVTNVEFLSRGIKEGCGNSILIK
                     VNQIGSLTETLNAIEMAHRHGYTTVTSHRSGETEDATIADIAVATNSGQIKTGSLSRSD
                     RMAKYNQLLRIEEELGDRAVYGYKRIN"
     CDS             8701..9267
                     /locus_tag="ctg7_7"
                     /transl_table=11
                     /translation="MEPIINSQLPEFKVQAFQNGNFKTVTNEDVLGKWAIFFFYPADFT
                     FVCPTELVDMAEKYEQFKSMGVEIYSVSTDSHFVHKAWHDASETIRKIQYPMLADPTGA
                     LSRAFGVMIEEEGMAYRGTFLVNPEGKIKVAEIHDNNIGRDASELLRKVEAAQFVASHD
                     GEVCPAKWKKGEATLKPSIDLVGKI"
     CDS             9287..10840
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_8"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.3e-47, bitscore:
                     152.2, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLESILKEQLKGIFAGLNANYTFDISISPAHESRQELLDLLGDVA
                     SCSDKISMRVSDGEGLEFILLKDGAKTGIKFRGVPNGHEFTSLLLAILNSDGKGKNFPD
                     ESICNRVKALNGPIHLTTYVSLTCTNCPDVVQALNAMTTLNPQIHHEMVDGAINQAEVD
                     ALKIQGVPSVFADGKLIHVGRGEFGELLSKLEAQYGINESLTEKTVKRYDVVVVGGGPA
                     GASSAIYSARKGLSVAVVAERIGGQVKETVGIENLISVPETTGTQLADNLRLHMRQYPI
                     DLLEHRRIEKVTIEGNEKVLSTAGGEIFKAPAVIIATGASWRKLNVPGEAEYIGRGVAF
                     CPHCDGPFYKGKHVAVVGGGNSGIEAAIDLAGICSKVTVLEFMDELKADLVLQEKAKSL
                     PNVEIFVSSQTTEVVGNGDKVTGIRTKDRKTGEERVIHLDGIFVQIGLAANSGVFKEIV
                     ETNRPGEIVIDAHCRTNVPGIYAAGDVSTVPFKQIIISMGEGAKAALSAFEDRVRGVLD
                     "
     CDS             10926..11276
                     /locus_tag="ctg7_9"
                     /transl_table=11
                     /translation="MDRLRKYLRILLPALFIAYLGCIIAFTHVHIVNGVTIVHSHPYHK
                     TDDGRPDHEHGYAEFQLLHQLSVLQITGAAFVAILLAAFYSFIRNLSFAPVYPDYIVPF
                     RGRRTLRAPPIF"
     CDS             11323..13632
                     /locus_tag="ctg7_10"
                     /transl_table=11
                     /translation="MNKFFIFILCLCCALTVAQATGEDCLNDSDANVFGHVLDKKTGEH
                     LPFINVLLKGTTIGTTTDNSGHYFLKNLPEGKFTLEYKALGYKTISKEVTLKKGKTLEI
                     NVELEEDQIALDGVVVSANRAETSRRLAPTLVNVLDAKVFTTTNAVNLAQGLNFQPGVR
                     VETNCQNCGFQQVRINGLDGPYTQILIDSRPIFSALSGVYGLEQIPANMIERVEVMRGG
                     GSALFGSSAIAGTINIITKEPLRNSGELSHTLTSIGGTSAFDNNTTLNASLVSENGKAG
                     LYLFGQNRHRSGFDQDGDGFTELPKLKNQTVGFRSYLKTSTYSKLTFEYHHMNEYRRGG
                     NLLDRPPHEADIAEQLEHSIDGGGLKFDLFSKDYKHKWSVFTSAQNTDRDSYYGTNQDP
                     NAYGKTTDLTVMAGTQYAYSFDKFLFMPSDLTAGLEYSFDHLKDEMIGYNRFTNQKVHI
                     ESAFLQNEWKNKRWSFLIGGRLDKHNMMDHVIFSPRANIRFNPTEDINIRASYSSGFRA
                     PQAFDEDMHISAVGGEVAMIQRAKDLSEEKSQSLSASVDFYHRFKNGIQLNFLVEGFYT
                     SLSDVFVLEDIGKDEQGNLIKERRNGSGAKVMGLTLEGKSVLTSWLSLQAGATFQRSRY
                     KEAEKWSDDENVPAETKMFRTPDIYGYFTATLTPFKRFTASLSGTYTGSMLVQHLAGYI
                     PLDKAVETPDFFDMNIKLAYEFPLYKELKLEVNGGVQNLFNAYQSDFDQGKNRDSSYIY
                     GPASPRSYFAGVKMSF"
     CDS             complement(13806..14798)
                     /locus_tag="ctg7_11"
                     /transl_table=11
                     /translation="MTDRRTFLRNISLLTLGGIASQKVMASNPTRSIPATDAVSSATAG
                     KKMGLQTYSLGQELLQDMPNGLNRLAKAGYTDLEIFGYREDTGKFGDYNPKNTTFIASK
                     DYKKMVDDAGLRISSSHLTPSVREYTKENMPKFDEFWKKATDIHAELGVSCMVQPSLPR
                     IENEDDAKVVSEIFNRAGEITKKAGILWGYHNHSNEFKRVLKAGEKPEQNPNPWAPPKG
                     TYIEELFLKNTDPDKVMFELDVYWAVMGQQDPVEWMENYPNRFKLLHIKDRWIIGDSGM
                     MNFPNIFKKAYEIGILGYYVELEGDKKGRTQFEGVEKSAAYLQAAPFVK"
ORIGIN
        1 ctttccctac acgacgctct tccgatctta ctatgaaaat atgattattc tcgtaaaatg
       61 cggataagat cggtttatta tggaattggc gttcttccga tagcaaatta aaagtagtat
      121 cggagaaatc cggagtcaac tttttcagta tgcccgaggc taataataaa taaaaatgtc
      181 cgtccgtccc ggcgaataag gtacgtacgg tttgagggcc tactccttct ctcggcaggt
      241 cccggaaccc atcgctagat ggggtgtagc aagagatcct gttttcctta caaatagcga
      301 gcgtgatgcc ggatgaatcg gacgctaata gatcgcattc catgtatccg gggaaagact
      361 cggtgacttt ccgttctttt agtgagaatt tattgatacc taaagaggtt gatatccata
      421 aaaagccggg ttctgcgtcg gatattttgt gaatgatatt actacaaaga gagtttttgt
      481 tatttaattc gaaacgatat acatacgtat cttttccgtt gtataagtta agtccgtcgt
      541 aagtcccgat ccacaaatag ccatccggat cttgatgcat gcagataatg gcgttgttcg
      601 agagatcaac catagaagtt ttatgcaata cggttgaggc aaataggtct gtttgcgtga
      661 tcaatataag gaaactggtt aacgctagaa taagccttgt gaatctcatg tatttaagat
      721 ttagtgtttg ttttcagcgc aaagataata tctttatgaa cgaacagaaa agaattcact
      781 tttttgttta cttttgcaaa aagcagggct ttcgtataaa ttagaatgtc tgacgtatga
      841 taatacgaaa taaagtaagt gacagatgga acaatgtgaa gagaattctc aagaaaatga
      901 cgatgtgata atagagaaag aaatttctaa attaatagaa gaacagcgtt tatttacgga
      961 gagtatatat gcttgtctgc cggtgggtat tgaaatttat gacgcacatg gtgtgctgcg
     1021 tagtataaac gaccatgcgt tgaggatgta tggtgtggac gaccggacat cggtggtgaa
     1081 tatagtcaat ctttacaaaa gtccatttgt tgattcagaa cttttagctc ggatacaatc
     1141 gggtgaagat atttccttgg agtttgagta tgattttgat cgggttaata aggatgcata
     1201 ttattcttcc cataataaag acacgatgat ctatggggtt aaagttatcc cgatatggag
     1261 tagaaaaaaa catcttatcg gacatatatt actcgcaaat gatatgactt ccgtgaaaga
     1321 ggtggaattc cgtacggaag aaagcaagaa aaatctggag atggccatga aagcggctaa
     1381 tatggcttct tgggtatatg atgtaaataa aaaggttttt aatccattat atggactaac
     1441 cgtagccaaa aaaaatatgc caatggaggc ggtactggat attttgcatc cccaagatcg
     1501 agctccgtta atccggctct tctctcaatt gataggaaat gagatagaac aaggacaaat
     1561 gactttgcgt ttctataacg agcaagaaga gatgtatcgt tattatgaga gccggatgcg
     1621 cctatcgaca gaacatcgtg gaaaattgca gatcatcggg acacaaatgg atataaccga
     1681 aaggttgcaa atggccaaga aagcgcagga tctgatcgca aaacgtgatc tggccatgaa
     1741 agtcagtaat attgttcatt gggattttga tgtaaattcc cagaaattcg aatcttataa
     1801 tgatccgatc aacgattacg tttcagatcg gttattgacc gtttcggagt atatggatgt
     1861 tatatacccc gaggaccggt ctgtttttta cgacgcaatg caatccctga tagctggaaa
     1921 gaatgtcacc atcaatttta cctgtcgcat acaaaccaag tatgatgaga cttggcagta
     1981 ttgtgatttt atgggtgtcc ctttcgatca agatgaaaat ggagatataa tacgctatac
     2041 gggattcagg caaaacattc ctaagatcca gcaattgaat cgggaactta aagaaagaaa
     2101 ttacaagata gagctttctt tcaagacggt tggtatgtcg tattgggatt ttgatgtaaa
     2161 aagcctgaaa ttcagtgctt ttaatgatcc tatcaatgat ttttattcgg aaaagacaat
     2221 cactcccgag gattatttga acgctacaca tccggatgat gtggtttttg tgcggaaata
     2281 tatggagcat atgttccggg gcatagataa agatttcaac gttaaatatc gttccaaaac
     2341 caaatgggat gacgagtggc agaccttatt ggttactgga atccaggttg aaagagataa
     2401 agaaggccat gtgactcgct ataccggtat tacgatcaat aatacgaagt gggagaagat
     2461 gattcagcaa ttgaaggaat taaaggagaa agcggaactt tcggatcgtc tcaagtctgc
     2521 gtttctcgct aatatgagtc acgagatacg taccccgtta aacgctattg ttggtttttc
     2581 agagttaatg gtaacttgtg atgatccgga agaaaaaaaa gaatatataa atatcatcca
     2641 atccaataat gagttgttat tgcgattgat caacgatatc cttgatcttt ccaagataga
     2701 gtcaggcata attgaacgta ggaaggagaa tttcaatctg gctaaggttt gtaatgagtt
     2761 atttgttacg attcaggcga agatgacaaa tccgaatgtc gagttacgtt tagatggtcc
     2821 caactcggag tgctgggtac ttctggatag aaaccggctt aagcaagtat ggatgaattt
     2881 cctcactaat gcggtaaaat gcaccaaatc cggatatatt aaaatgggat atggcattga
     2941 aaggaaaggt cttcgtatct atgttgagga tacgggaatc ggtataccgg atgatttgca
     3001 tgacaaagta tttacccgtt ttgagaaatt gaatgagttc tcgcagggta ccggacttgg
     3061 cttgacgatc tccagagcta tcgtagaagc ggcaggggga gaagtgggct ttacttcaaa
     3121 acttggtgtc ggatctactt tttgggcatg gttgcctctt cgcccttagg tctgactccc
     3181 catttattgg taatgtcctt ttaaaatagt gaaggatgag aagctttttt atcgcaattt
     3241 atagggattt tagaactggt gtagcatatg tgacagaaat atgacgataa ttctcctacc
     3301 tttgcggcgg taaaaatgtg gtattagata agattgttta tgaaatttga gaatgagtgc
     3361 tgggatcact ttaagggtga gacctggaaa agagagatca atgtaagaga ttttatccag
     3421 agtaactata cgccttatga aggggatgat tcctttttag tcgcttcttc cgagaagact
     3481 cgtaaggtct ggaacaagct gaccgagatg tttaaggtcg agagggaaaa gggaatttat
     3541 gacgccgaga caaaattacc tcaagggatc gatgtatatg gcccgggcta tattgataag
     3601 gagaatgagg tgatcgttgg gttacaaacc gatgctccgc tgaaacgtgg tatcttcccg
     3661 aagggcggta tccgtatggt cgagaatagc ttggaagctt atggttatca tttggacccg
     3721 atgacgaaag agatctttac gaagtatcgt aagactcata acgagggcgt tttctccgca
     3781 tatacggaag agatgattgc cgcacgtcgt tcggctatta tcaccggtct gcccgatgcg
     3841 tatggtagag gacgtattat tggtgactat cgtcgtgtcg ctttatatgg tacggcaatc
     3901 ttgatcgagg agaaaaagcg tttcttgaat cgtttggata tccaagagat cacggaagag
     3961 atcatccaga gccgtgagga gatttccgaa cagatcaagg ctttgaaagc gttcgagaaa
     4021 atgtgcgcta gctatggctt tgatgtgact cgtccggcac aaaacgctcg tgaggcggtt
     4081 cagtttgtgt acttagctta tctggcggcg gtaaaagacc aagatggcgc ggcgatgtct
     4141 atcggacgta cttctacgtt tttggatatt tatatcgaga aagacatccg tgagggtaag
     4201 ttgaccgaag aggaggcgca agaattggta gaccagctga tcatcaagtt gcgtatcgtt
     4261 cgtttcttac gtacgccgga atacaatgat ttgttctccg gtgatccggt ttgggtaaca
     4321 gagtccttgg gcggccaagg agtggatggt cgttctttgg taacaagaac ttcctatcgt
     4381 tatctccata cattatataa tctaggtccg gcaccagaac ccaatttgac ggttctgtgg
     4441 tttaagaacg ctcccgagaa ctggaaacgt ttctgtgcca aggtctctat cgatacgtcg
     4501 gctatccaat atgagaacga cgatttgatg cgtccggatt atggagatga ttatggtatc
     4561 gcttgttgcg tttctcctat gaagatcggt aagcagatgc agttcttcgg agcccgtgcg
     4621 aatttggcga aatgtttatt atatgcgatc aacggaggac gggatgagcg cagcggcgta
     4681 caggtagccc cgatgttcga gccggttcgc ggcgagtatc tggaatacga tgaggtgatg
     4741 gctaagtatg agcaaatgat gcgctggttg gcgaaagtgt atgtgaacgc cttgaagata
     4801 atccattata tgcatgataa atacgcgtat gaggcattcg agatgtcgct tcacgatggg
     4861 gatgtagagc gtatccgtgc gacaggtatc gccggtcttt ctatcgttgc cgattcgttg
     4921 gctgctatcc gtgatacgaa agtacgtgtg atccgtgacg agcgtggctt ggcggttgat
     4981 ttcgaacgtg agggcgaata tgttcctttc ggtaataacg acgatcgtac ggatagtatc
     5041 gctgtagaga tcaccgagaa gttcatggaa tatttgcgtc agcacgagac ctatcgccat
     5101 gcgaaaccta cgcagtccat ccttacgatc acctctaatg tggtatatgg taagaagact
     5161 ggtacgacac cggatggccg tatcggtgga actcctttcg ctccgggcgc gaaccctatg
     5221 aacggtcgtg atacgaaagg tgctatcgct gcgctagctt cggtagcgaa gcttccattc
     5281 cagcatgcgc acgacggtat ctcttatact ttcgctgttt ctccggctac gttgggaaag
     5341 gagcgtgaag tgcagatcaa taatctggtt agcttattgg atggctattt tactccggat
     5401 ggaggtcagc atctgaatgt taacgtattt gataaggatt tgttgatcga cgctatggaa
     5461 catcccgaga aatatccgca acttacgatc cgtgtatccg gatatgcggt aaacttcgtg
     5521 aaactgactc gtgaacaaca gttggatgtt atttcaagaa ccattaacca ttcactgtaa
     5581 gtgataaaag gtaagataca ttcattagag agtttcggga ccgtagatgg tcccggaatt
     5641 cgctttgtcg tttttatgca gggctgcccg ttgcgttgcc tgtattgcca taacccggat
     5701 acttggaacc cgaaagggaa ggtgaaatat cagatgactc ccggcgagct attgacggaa
     5761 gtcttacggt ataagagttt tatcgcccgt gggggggtga ctgttaccgg tggggaacct
     5821 ttattgcaac ctgagtttct gaaagagttt ttccgtttgt gccaagagca aggtcttcac
     5881 acagctttgg acacatctgg tttcgtatgt acctcaaaag cttgggaagt cttggattat
     5941 gcggacttag tgttattgga catcaaaacc ttaaacccgg atttacatcc gttactggcg
     6001 ggtgtcaagc aggataatac gcttctgttc ttggatgaat tggagagacg tggcatagat
     6061 acttggattc gccatgttat tgtccccgga tatacggata atgacgagtg gctggaggcg
     6121 ttagctcggt atgtcagttc atataaagtg gttcgcaaag tggaattatt gccttatcat
     6181 acgatgggaa cctataaata tgagcaatta ggcctcgatt atccgttaaa gggggtggaa
     6241 cccttatcaa aagaacgttt agataatgcg aaagcgatat tctctcgcta caaaccagaa
     6301 aataacaagg cctgatctct cgatcaagcc ttgcgattat gcaacagcta atcagggaaa
     6361 acaatctaat ccgattagct tttaaacgat agtaataatt ttttgcctag actaaccttg
     6421 actatttaat atgtgtttgt tttgttatat gcaacaaata tctatttttg taaggagata
     6481 aaaaatgata tagatcagaa aatgatgaat agtatgaaga caccacaaga aatagccgaa
     6541 atgatatcca aacgttttta tccattaccc gatgcggatt tggattctct ggcctcgatc
     6601 atagaatcaa gtaaggctgc gaaaggaaaa ttattgttgg ataacggaca aatatctaaa
     6661 tatttatatt atgtggaatc gggattatta cgccagtttt actataagaa taaacgtgat
     6721 attaccgagc atttctcctg tgagggaaat atcgttattt gtatagccag cacattccaa
     6781 agagaaccga cgcgtttatt aatcgaggca ttggaaccga cggtttatca ccggatctct
     6841 ttttcggaat ttagcgattt attgaaaaca tctttagcta ttaatagatt gtaccagaaa
     6901 atactggagt gggctttgat gctttcgcaa gagaaagcgg actcttggcg ttttgagtcg
     6961 gcaagaaaac gttatctgcg ttttcaacag gaatatccgg aagtagcgaa gcgtgcttct
     7021 gtcaatcata tcgcctcgta tttattgatg acacccgaat ctttgagccg ggtacgggcg
     7081 ggagtgttgt agcctctacc tacattcagg tattattgag gcgaaaatag caatttgtgg
     7141 tgatttcacg gttctagtaa tccatctata tttgcgtcag tttaaaaaac gtagaagcaa
     7201 tgaaaataga aaagattaca ggacgtgaga tcctagattc aagaggtaac ccgacagtag
     7261 aggttgatat tttactagag tccggcgtta tgggccgtgc gtctgtgcct tccggtgcgt
     7321 ccaccggcga gaacgaggct ttggagttgc gtgatggcga caagaagcgt tatggtggta
     7381 aaggcgtatt gaaagcggtt gagaatatca atacgattat cgctccggca ttgaagggga
     7441 tgtctgcctt ggatcagata ggtatcgatc atgcgatgtt ggctttggac ggtacgaaaa
     7501 ctaaatcgaa actaggtgcg aacgctatcc ttggcgtttc tttagctgta gcgaaagctg
     7561 ccgcaaatta tttggatatt cctttatata gatatattgg tggaacgaat acctacgtga
     7621 tgcctgttcc gatgatgaat ataatcaatg gcggttcgca tagcgacgct ccgatcgctt
     7681 tccaagaatt tatgattcgt ccggtaggtg ccgcttcttt caaggaaggc ttacgtatgg
     7741 gtgctgaggt attccatgcg ttgaaaaagg tattgcacga tcgtgggtta agtaccgctg
     7801 ttggtgatga gggtggtttc gccccgaatt tggaaggtac ggaagatgcc ttgaactcaa
     7861 ttatcgtcgc tatcaaggcg gctggttatg aaccgggcaa ggatgtgatg atcggtatgg
     7921 attgcgcttc ttctgagttt tataaggatg gaatctacga ttacacgaag tttgaaggag
     7981 aaaaaggagt gaaacgtact tccgacgaac aagtggatta tctggaaaag ctgatcaacg
     8041 aatacccgat cgattccatt gaggatggta tgagtgagaa tgattgggct ggttggaaga
     8101 aactgacaga tcgtatcggt aaccattgcc aattagtcgg agatgatttg ttcgtgacaa
     8161 atgtagagtt cctttcaagg ggtattaaag aaggttgcgg taactcaatc ttgatcaagg
     8221 taaatcagat cggttccttg acggagacac tgaacgctat cgagatggct caccgccatg
     8281 gatacacgac cgttacttca caccgttccg gtgagacgga agacgctacg atcgccgata
     8341 tcgctgtcgc taccaatagc ggacagatca agacgggatc attaagtcgt tcggaccgta
     8401 tggctaaata taaccagctg cttcgtatcg aggaggaatt gggagaccgt gctgtatacg
     8461 gatacaaaag aatcaattaa gtatataaag taaattataa tcgctaatta tgtagtaatc
     8521 caaaacccaa gatattgaag ggtttatccg tgaggatagg ccctttttat tgattgataa
     8581 agtattatct ataacctcat aaaatatatc gattaaaaaa attgttttaa tgaagaaata
     8641 tgttatattt ttgtatcgga aataaaaaca aatagtattc atttaaaaat aggaacaagt
     8701 atggagccga ttattaattc tcaacttccg gagtttaaag tacaagcttt tcaaaatggt
     8761 aatttcaaga ctgtaaccaa cgaggacgtc ttgggtaagt gggctatctt tttcttctac
     8821 ccggccgatt ttacatttgt ttgtccaaca gagttggtcg atatggctga gaagtatgag
     8881 cagtttaaat caatgggagt agaaatttac tctgtaagta cagattctca ttttgtacat
     8941 aaagcttggc atgacgcttc cgagactatc cgtaagatcc aatatccgat gttggcggat
     9001 cccactggag cgctgagtcg tgcgtttggt gtgatgattg aggaagaggg tatggcatac
     9061 cgtggcactt tcttggtaaa tccggaagga aagatcaaag tggccgagat tcatgataac
     9121 aatatcggtc gtgacgcttc cgagttactt cgtaaagttg aagccgctca gtttgtcgct
     9181 tcacatgatg gtgaggtttg tcctgctaaa tggaagaaag gggaggctac cttgaaacct
     9241 agcattgact tggtagggaa aatctaaata attaagagta tagatcgtgt tagaatcaat
     9301 attaaaagaa caattaaaag gtatattcgc agggttaaat gcgaattata cctttgatat
     9361 atcgatctct cctgcgcatg aaagtagaca ggaattgttg gatttattag gtgatgttgc
     9421 ctcttgttcg gataaaatat ctatgcgagt atctgatggg gagggattgg aattcatttt
     9481 attaaaggat ggagcgaaaa cggggattaa gtttcgtgga gtacctaatg gacacgagtt
     9541 tacttccttg ctgttggcga tcttgaattc agatgggaaa ggcaagaatt ttccggacga
     9601 gagcatttgt aatcgtgtta aagccttgaa tggcccgata catctgacga cctatgtctc
     9661 tttgacttgt acgaattgcc cggatgtggt acaggcatta aacgctatga cgactttaaa
     9721 tcctcagatc catcatgaga tggtagatgg ggctatcaat caggcggaag ttgatgcctt
     9781 gaagatacaa ggcgtcccct ccgtttttgc ggacgggaaa ctgatccatg taggacgtgg
     9841 ggaattcggt gaattgttat cgaagctgga agctcagtat ggaatcaatg agagcctgac
     9901 agagaagacg gtaaaacgat atgacgtggt tgtggtcggt ggagggccgg ctggtgcttc
     9961 ttccgctatt tattccgcac gaaaggggct gagtgtcgct gtcgtggcgg agcgtatcgg
    10021 cgggcaggtg aaggagacgg taggaattga gaatctgatt tcagttccgg agacaacagg
    10081 tacccagttg gctgacaatc tgcgcttgca tatgcggcaa tatccgattg acctgctgga
    10141 gcatcgtcgt atagagaagg taacgataga aggaaacgag aaggttttgt ctacggctgg
    10201 aggtgagata ttcaaggctc cggcggttat tatcgctacg ggcgctagct ggcgtaaatt
    10261 gaatgtaccg ggtgaggcag agtatatagg gcgtggagtg gctttttgtc ctcattgcga
    10321 cggtccgttt tataagggaa aacatgtcgc cgtggttggc ggtggaaatt ccggtatcga
    10381 ggcggctatt gatttggcgg ggatctgttc gaaagtaacc gttttggagt ttatggatga
    10441 gttaaaagcg gatctagtct tgcaagagaa agcgaagagt ttgccgaatg tcgagatctt
    10501 tgttagttca caaacaaccg aggtggttgg aaatggcgac aaggtaaccg gtatccgtac
    10561 aaaggatcgt aagacagggg aagagcgtgt tattcattta gacggtattt ttgttcaaat
    10621 cggcttagcc gctaatagtg gtgtctttaa ggagattgtc gaaacaaatc gtcccggtga
    10681 gatcgtgatt gacgcacatt gccggacgaa tgtcccgggt atttatgcag cgggcgacgt
    10741 ttccaccgta ccctttaagc aaatcattat ttctatggga gaaggcgcca aagcggccct
    10801 ttcggccttt gaagatcggg tacgtggcgt acttgattga ggaaagtacc tacaaatagg
    10861 taatttttga acagcgtatc tcttttatcg gttatattac tatatttgcg atcgagagaa
    10921 aagagatgga tagattaaga aaatatctga ggatattact ccctgcgctg ttcatagcct
    10981 atttgggatg tattattgcg tttacccacg ttcatattgt caacggggta acgatcgtcc
    11041 attctcaccc gtatcataaa acggacgatg gtcgtccgga ccatgaacat ggctacgccg
    11101 agtttcagtt gcttcatcag ttatctgtct tgcagataac aggtgcggct ttcgtcgcta
    11161 ttctgctggc ggctttttat tcctttatcc gtaacttatc tttcgctccg gtctatccgg
    11221 actatatcgt tcccttccgg ggaagacgta cgcttcgggc tcctcccata ttctgatatt
    11281 gtgagattaa taacattgta ttacttatca gaataaatta aaatgaataa atttttcatc
    11341 tttatactat gcctgtgctg tgccctaacg gtagctcagg ccacgggaga ggactgtcta
    11401 aacgactcag acgcaaatgt tttcggacat gtattggata agaaaacagg ggaacatctt
    11461 ccctttatca acgtattgtt aaaaggtacc acgatcggta cgaccaccga taactcggga
    11521 cattatttcc tgaagaatct gccggaaggt aaatttacgc tagaatataa agcgctcggg
    11581 tataagacta tctctaaaga agtgacccta aagaaaggaa aaaccttaga gattaatgta
    11641 gaactggaag aagaccagat cgccttggat ggcgtggtgg tatctgcgaa tcgtgcggaa
    11701 acttcccgcc ggttggctcc cacattagtg aatgtattgg atgcgaaggt ttttactacg
    11761 accaatgcgg tgaatttggc acagggacta aatttccaac cgggtgtacg ggtagagacg
    11821 aattgccaga attgcggttt ccagcaagtc cggatcaatg gattagacgg accttatacc
    11881 caaatactga ttgattcacg tcccatattc agcgctttat ccggcgtata tgggcttgag
    11941 caaataccgg cgaatatgat cgagcgggta gaggtgatgc gaggaggggg atcggcactg
    12001 ttcggctcgt ccgctatcgc cgggacaatt aatatcatca cgaaggagcc cttgagaaat
    12061 tccggggaat tgtcgcatac attaacctcg atcggtggga catctgcttt cgataataat
    12121 acgaccctaa atgcctcttt ggtatcggaa aatgggaaag cgggcttata tctttttggc
    12181 cagaaccgtc atcgttcggg ttttgatcag gatggagatg gttttacgga gttgcctaaa
    12241 ttgaagaatc aaacggttgg tttccgttcg tacctgaaaa cgagtactta tagtaaattg
    12301 acattcgagt atcatcatat gaatgaatac cgcaggggag gaaatctgtt ggatcgtccg
    12361 cctcatgaag cggatatcgc cgaacagttg gagcattcga ttgatggagg aggtctgaaa
    12421 ttcgatcttt tctccaagga ttacaaacat aaatggagtg ttttcacttc tgcccagaat
    12481 acagaccggg atagttatta cgggacgaac caagatccga acgcttacgg caagactacg
    12541 gacctgacgg ttatggccgg tacgcaatat gcttatagtt ttgataaatt cttatttatg
    12601 ccatcggatt tgactgccgg tttggagtat agtttcgatc atttgaaaga cgagatgatc
    12661 gggtataatc gctttacgaa tcagaaggtg catatcgaga gcgcattttt gcagaatgag
    12721 tggaaaaata agcgatggag cttcttgatt ggcggtcgtt tggataaaca taatatgatg
    12781 gatcatgtaa tattcagccc tcgtgcgaat atccgtttta acccgacgga agatatcaat
    12841 atccgggcta gttattccag tggtttccgt gccccgcaag cgttcgatga ggatatgcat
    12901 atctcggcgg tcggcggaga ggtcgctatg atccagcgtg cgaaagattt atccgaggag
    12961 aaatcgcaaa gcttgagtgc ttcggtcgat ttttaccatc gttttaagaa tggtatccag
    13021 ttgaacttct tggtggaagg tttttacacc agcttaagtg atgtgtttgt cttggaagat
    13081 atcgggaaag atgagcaagg caatctgatt aaggaacgtc gtaacggttc cggggcgaaa
    13141 gtgatgggat taaccttgga aggaaagtcg gtgttaactt catggctatc tttgcaagcg
    13201 ggcgctactt tccagcgaag ccgttataaa gaggccgaga aatggagcga tgacgagaat
    13261 gtgccagccg agacaaagat gttccgtacg ccggatatct atggttattt tacggctact
    13321 ctcacgcctt tcaaacgttt cacggcttcc ctgtcgggaa cctatacggg aagtatgttg
    13381 gtgcagcatt tggcgggata tatacctttg gataaggcgg tggagactcc ggatttcttt
    13441 gatatgaata tcaagcttgc gtatgagttc ccgctttaca aagagctgaa actagaagta
    13501 aatgggggcg tgcagaatct gttcaacgct taccaatccg actttgacca aggtaagaac
    13561 cgggattcct cctatatcta tggcccggct agcccgagaa gttattttgc cggtgtaaag
    13621 atgagctttt aatcatgtaa tgccctttga aaaaacatgt acgtgtttcg tgaaaaacac
    13681 gtacgtgttt ccgaaaaaag acgtacgtgt ttttttgaag gcaaaataaa taaaaagaca
    13741 gtgttcccaa gcgtatgatc gccctacgga aacactgtct tttttatggg ataaatcggg
    13801 atgttttatt taacgaacgg agcggcttgc aaataggcgg cgctcttctc tacgccctcg
    13861 aactgggtac ggcctttttt gtcaccttcc agttccacgt agtagccgag gataccgatc
    13921 tcgtacgctt ttttgaatat attcgggaaa ttcatcatac cggaatcacc gatgatccaa
    13981 cgatccttga tgtgcaataa cttaaaacga ttcggataat tctccatcca ttccacggga
    14041 tcttgctgcc ccataacggc ccaatataca tccaactcga acataacctt atccggatcg
    14101 gtatttttca ggaataactc ctcgatataa gtacccttag gaggtgccca cggattcggg
    14161 ttctgttccg gtttctcgcc ggctttcaat acccgtttga actcattgct gtgattatgg
    14221 tagccccata ggattcccgc tttcttcgtg atctctccgg cacggttgaa gatctccgat
    14281 actactttgg cgtcatcctc gttttcgata cggggtaaac tcggttgtac catacaacta
    14341 acacctagct cggcatggat atcggttgcc tttttccaga actcgtcgaa tttgggcata
    14401 ttctctttcg tatactcgcg aacggaaggg gtcaggtgtg agctactgat tctcaaaccg
    14461 gcatcatcca ccattttctt ataatccttg gaggcgatga atgtcgtatt tttaggatta
    14521 taatcaccga atttaccagt gtcttcccta tatccgaaaa tctccagatc ggtatatcct
    14581 gcttttgcca atcggttcaa cccgttaggc atatcttgca gtaactcctg tccgagcgaa
    14641 taggtttgca atcccatctt tttcccggcg gttgccgagg ataccgcatc cgtggcgggt
    14701 atggatctgg tgggatttga agccattact ttttggctgg ctatgccccc taaagtaagt
    14761 aatgaaatgt ttctcaaaaa tgttcttctg tctgtcatgg tgataaagaa ttaaaattaa
    14821 acatctgttt ctcgcaaata tagttaacct ttttgaagtt tattaagaaa atgtctctca
    14881 aaaacttgcg attgggttta aatagattta aaatttgaca taactcaatt ttacgaactt
    14941 actccataca tccaattacc tgaataaggg gattgtttgg tatacctccg tggattttta
    15001 gtgtgatttt acccattctt aggtattgtg gggcggtagt ctctgatcgt aactttgcaa
    15061 cgttttaaat aacataattg attaaatgat gatgaagaaa atcagagggc ttttcctctc
    15121 ctttttatta ttgcttattt ccatctcggt tttttctcaa cataaaacaa tgatatcggg
    15181 taaagtcctg tccacggaaa aaacaaccgt ggatttcgct accgtttatc taaaaggtac
    15241 gaattacggc gggactacga atgaggaagg tatctatcat cttcaagctc ccgcgggaga
    15301 atatacatta gtagtatcgg ctatcggata taagacggta gagaaacccg tgaaactgat
    15361 gcgtggggaa cggacaaaga tgaatgtggt aatcagccct caggctacgg agttggatga
    15421 ggtggttgtc gtttctaatg gcgtgacccg gctcaagcgt tctgcgttca atgccgtggc
    15481 cctcgatacg aaagccttgc aaaattcaac ccagaacttg agtgaggctt tggctcaagc
    15541 gcccggaatg aagatccggg agtctggcgg tgtcggctcg gatatgcaac tgatgatgga
    15601 tggatttacc ggcaagcata tcaagatctt tatcgatggg gttccgcaag aaggtgtcgg
    15661 cagttctttc ggactgaata acattccggt gaattatgcc gagcgtatag aggtctataa
    15721 gggtgtggta ccggtgggtt tcggaacaga cgctatcgga ggtgttatca atatcatcac
    15781 caagaagaac cggaacaaat ggttcttgga tgcttcttat tcatacgggt ctttcaatac
    15841 gcataaatct tatgtgaact tcggacaaac tttccggagc ggactcacgt atgagatcaa
    15901 cgttttccag aattattcgg ataataatta ctatgtggat actccggtga aggactttac
    15961 gaccggagcg atcaataaga aaaagatcga gcatgtgaag cgttttcatg atacgtatca
    16021 taacgaggcc gttatcggga aaatcggttt cgtggataag aaatgggcgg atcgtttgat
    16081 gtttgggttt acctattcac atatgtataa agatatacag acgggcgtac gccaagaagt
    16141 ggtgtttggc ggcaaatatc ggaagggata ctcgatcatg ccgtcgttgg actatcgcaa
    16201 gcgtgatttc ttcgttaggg gcttggatgt ggtattgacg gcgaattata ataagaacat
    16261 gacgaacaat gtagatacct cttcctatga atataattgg cgtggcgaga tgcgt
//
