LOCUS       c00190_gnlPro..         5128 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AGIFDOFI_190.
ACCESSION   c00190_gnlPro..
VERSION     c00190_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 08:50:31
            Original ID  :: gnl|Prokka|AGIFDOFI_190
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5128
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5128
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1:4528]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2..4528
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..5128
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..5128
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             2..256
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ILVD_EDD"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg190_1"
                     /sec_met_domain="ILVD_EDD (E-value: 8.1e-29, bitscore:
                     89.4, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="GTSGLSIGHVSPEAAAGGNIGKIKDGDIIEIDIPNRSINVKLTDE
                     ELAARLMTPVTRNREVSKALKAYASMVSSADKGAVRLID"
     CDS             348..2099
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg190_2"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.9e-48, bitscore:
                     151.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADNNKKSNFSSLSQGEGRGEALITGAEALMRSLEHQGVKTIFGY
                     PGGSIMPVFDALYDHRKELNHILVRHEQGATHAVQGFARVSGEVGVCLVTSGPGATNTI
                     TGIADAMIDSTPIVVIAGQVGTNFLGTDAFQEVDLVGITQPITKWSYQIRRAEDVAWAV
                     ARAFYVAKSGRPGPVVLDFAKNAQVEKTEYAPTKVDYVRSYLPVPEMEPEAIRKAAELI
                     NGAERPLVLVGQGVELGEAQQELRAFIEKAGMPAGCTLLGLSALPTNHPLNKGMLGMHG
                     NLGPNINTNKCDVLIAVGMRFDDRVTGKLETYAKQAKIIHFDIDPAEIDKNVKTDVAVL
                     GDCKETLAAVTQLLEPANHQEWIDSFRQYEEVEEEKVIRPELHPAGKALSMGEVVRAVS
                     EATHNEAILVTDVGQNQMMSARYFKYSKERSIVTSGGLGTMGFGLPAAIGATFGRPDRT
                     VCVFMGDGGLQMNLQELGTIMEQKAPVKMILLNNNFLGNVRQWQAMFFNRRYSFTPMMN
                     PDYMKIASAYDIPARRVMTREELAKAIDEMIATDGPFLLEACVEEEGNVMPMTPPGGSV
                     NQMLLEC"
     CDS             2132..2692
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg190_3"
                     /sec_met_domain="ALS_ss_C (E-value: 4.2e-20, bitscore:
                     60.8, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKKLYTIIVHSENFAGLLNQVTAVFTRRQINIESLNVSASSIKG
                     VHKYTITAWTDKDTIEKVTKQITKKIDVLQAHYFTDDEIYQHEIALYKITTPTLEEKPE
                     VSKVIRKYNARIVEVNAVFAIVEKNGMSEEITNLYEELRQLDCVLQFVRSGRVAITTSC
                     FERVNEYLADREAKYRQSKHQES"
     CDS             2689..3120
                     /locus_tag="ctg190_4"
                     /transl_table=11
                     /translation="MMSENNKIGTYKFVAEPFHVDFTGRLTMGVLGNHLLNCAGFHASD
                     RGFGIATLNEDNYTWVLSRLAVELDEMPYQYEDFSIQTWVENVYRLFTDRNFAIIDKEG
                     KKIGYARSVWAMISMNTRKPADLLALHSGSIVXXXXLAR"
     CDS             3141..3434
                     /locus_tag="ctg190_5"
                     /transl_table=11
                     /translation="VASKEPVAALVAKYSDIDINGHVNSIRYIEHILDLFPIEMYKEKR
                     IRRFEMAYIAESYYGDELTLFMDDAGEGVYDVEGKKNGSEVVCRSKVIFTEK"
     CDS             3485..4528
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg190_6"
                     /sec_met_domain="IlvN (E-value: 2.9e-47, bitscore: 149.2,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 2.4e-41, bitscore: 130.3,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQLNFGGVIENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     ACNLRDNGFNVIVGQRPGKTYEKAVADGWVLGETLFGIEEACQKGTIVMCLLSDAAVMS
                     VWPTIKPYLTPGKALYFSHGFAITWNDRTGVVPPKDIDVIMVAPKGSGTSLRTMFLEGR
                     GLNSSYAVYQDATGKAFDKTIALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMT
                     PFHDAIKPVVQKLYASVKSGNEAQISIDSNSKPDYREKLNAELKALRESEMWQTAVTVR
                     KLRPENN"
     CDS             complement(4590..5126)
                     /locus_tag="ctg190_7"
                     /transl_table=11
                     /translation="EAAPEVRYRGILDWDTPIHWIDTSEMDFKEEFVGETFGRINKAEA
                     DLLLSELKIYINRIGGSRILEEKIDFGIISPYKAQVQYLRNKIKADASLKPYRSLFTVN
                     TVDGFQGQERDVIFISLVRANEEGQIGFLNDLRRMNVAITRARMKLVILGEAETLKHHG
                     FYRKLLEFIQNIGNQ"
ORIGIN
        1 tggtacttcc ggactaagta tcggacatgt ttctcccgaa gcggctgccg gtggtaatat
       61 cggcaagatt aaggatgggg acattatcga aattgatata ccgaaccgtt ctatcaatgt
      121 gaagttgacg gatgaagagc ttgcagcacg ccttatgact ccggtaaccc gcaaccgtga
      181 agtctccaaa gcattgaaag catatgccag tatggtgagt tccgctgaca aaggggctgt
      241 gaggctgatt gattaaaagc ccccctttcc gaaagcgagg ggaggagaga atgaaacaaa
      301 tttttcaagc tactattgag cttttaaata taatgaatag ataaagtatg gctgataata
      361 ataaaaagag taacttttcc tccctctccc aaggagaggg tcggggtgag gctctaataa
      421 caggcgcaga agcattgatg cgctctctgg agcatcaggg agtaaagact attttcggtt
      481 atccgggagg gagcatcatg ccggtattcg atgccttata cgaccaccgg aaggaattga
      541 accacatctt ggttcgccat gaacaaggag caacccatgc ggtacaaggc tttgcacgtg
      601 tatcaggcga ggttggcgtt tgtctggtta ccagtggacc gggtgctacc aatactatca
      661 cgggcattgc agatgccatg attgacagta cgcctatcgt tgtcattgcc ggccaggtag
      721 ggacgaactt cttgggtacg gatgcatttc aggaagtgga cttggtaggc attactcagc
      781 ctatcacgaa atggagttac cagattcgtc gtgcagaaga tgtggcctgg gcagtggcac
      841 gtgctttcta tgtggcaaag agcggacgtc cgggaccggt cgtgctggat tttgctaaaa
      901 acgcccaagt ggagaaaaca gaatatgcgc ctactaaggt ggactatgtc cgtagctatc
      961 ttcccgttcc cgaaatggag ccggaggcca tacggaaggc tgctgaatta ataaatggtg
     1021 cggaacggcc tttggtgctg gtaggacaag gcgtggagct gggagaagcc cagcaagagc
     1081 ttcgtgcttt cattgagaaa gccggaatgc ctgccggatg cactttattg ggactttccg
     1141 cattacctac gaaccatccg ttgaacaaag gaatgcttgg tatgcacggt aacctggggc
     1201 ccaatatcaa taccaataaa tgtgatgtcc ttatcgccgt aggcatgcgc tttgatgacc
     1261 gtgtgacggg taaattggaa acatatgcca agcaggcgaa gattatccac tttgatattg
     1321 accctgccga aatagataag aatgtaaaga ccgatgttgc tgtcctggga gattgcaaag
     1381 agacactggc tgccgttacc caattgctgg aacccgccaa ccatcaggaa tggattgaca
     1441 gtttccggca atacgaggaa gtggaagagg aaaaggtaat ccgtccggaa ttacatccgg
     1501 caggaaaagc gctaagcatg ggtgaggtgg tgcgtgctgt gagtgaggct acccataacg
     1561 aggcgatatt ggtgactgat gtcggccaga atcagatgat gtccgcccgt tatttcaaat
     1621 acagcaagga acgtagcatt gttacttccg gtggcctggg tactatgggc ttcggccttc
     1681 cggcagctat cggtgccact tttggacgtc cggaccgcac ggtatgcgta ttcatgggag
     1741 acggcggctt gcagatgaac ctgcaggaac tgggtaccat catggaacaa aaggctccgg
     1801 tgaagatgat tctgttgaac aataacttcc tgggcaatgt tcgtcaatgg caggcgatgt
     1861 tcttcaatcg tcgttattcg tttactccga tgatgaatcc ggattatatg aagattgctt
     1921 cggcatatga tattcctgca cgcagggtaa tgacccgcga ggagctggca aaagcgattg
     1981 acgagatgat agcgactgac ggaccgttcc tgctcgaagc ttgtgtggag gaagaaggaa
     2041 atgtaatgcc gatgacacct ccgggcggtt cggtcaatca gatgttgttg gaatgctgaa
     2101 gtcatgcgaa attaaagaac ttactctatc tatggataaa aaactatata caatcattgt
     2161 tcattcggaa aactttgccg gtttgctgaa tcaggtgacg gctgtgttta cccgccggca
     2221 gataaacatc gagagtttga atgtatcggc ctcctccatc aagggggtac ataaatatac
     2281 cattaccgct tggacggaca aggataccat tgaaaaggtg accaagcaga ttaccaagaa
     2341 aatagatgtg ctgcaagccc attatttcac ggatgatgaa atctatcagc acgagattgc
     2401 cctttataaa ataacgaccc ctacgctgga agaaaaaccg gaggtgtcca aagtaatccg
     2461 taagtacaat gcccgtattg tggaggtgaa tgctgtattt gccattgttg agaagaatgg
     2521 catgagtgag gaaataacca atctttatga ggagttgcgc cagttggatt gcgtacttca
     2581 gttcgtccgt tcgggtcgcg tagccattac gaccagctgc tttgagcgtg tcaatgaata
     2641 tctggcggac cgtgaagcaa aatatcgtca aagtaaacac caggaatcat gatgagcgag
     2701 aacaataaga taggtaccta caagtttgtt gccgaaccgt ttcatgtcga ctttaccgga
     2761 cggctgacaa tgggagtatt gggcaaccat ttgttgaatt gtgcgggttt ccatgccagc
     2821 gaccgcggtt ttggcatcgc gactctaaac gaggacaatt atacttgggt attgtcccgt
     2881 ctggctgtcg aactggatga aatgccttat cagtacgaag atttctccat tcagacttgg
     2941 gtggagaatg tctatcgcct ttttacagac cgtaatttcg ctatcatcga taaggagggt
     3001 aagaagattg ggtatgcacg ttccgtttgg gcgatgatta gcatgaatac ccgtaagccg
     3061 gcagatttgc tggctcttca tagtggcagc attgtagnnn nnnnnnncct tgcccgatag
     3121 aaaaaccttc gcggataaag gtggcctcaa aggaaccggt tgctgctttg gtagccaaat
     3181 acagtgatat tgacattaac gggcatgtga acagcatccg ttacatcgag catatccttg
     3241 atttgttccc gatagagatg tataaggaga agcgcatccg tcgttttgaa atggcatata
     3301 tagccgaaag ctattatggg gatgagttga ctttgttcat ggatgatgcc ggtgagggcg
     3361 tttacgatgt ggaggggaaa aagaatggca gcgaagtggt ctgtcgctct aaagtgatat
     3421 ttacagagaa ataaataaat ttatcaacgt tggcgtaagc cacaaataaa aattaaaaca
     3481 aaaaatggca caattgaatt ttggcggtgt tattgagaat gtaatgaccc gcgaagaatt
     3541 tcctttggaa aaagcacgtg agattttgaa agatgaaaca attgcagtaa tcggttatgg
     3601 cgtacaaggc ccgggccagg cttgcaactt gcgtgataac ggtttcaatg tgattgtagg
     3661 acaacgtccg ggtaagacat acgaaaaggc tgtggctgac ggatgggtac tgggtgagac
     3721 tttgttcggc atcgaagagg cttgtcagaa aggtactatc gtcatgtgtc tgttgtctga
     3781 cgcagctgta atgtctgtat ggccgactat caaaccttat ttgactcccg gaaaggctct
     3841 ttacttctct catggttttg ctattacctg gaacgaccgt accggcgtgg ttcctcctaa
     3901 agatattgat gttattatgg ttgctcccaa aggttccggt acttcacttc gtaccatgtt
     3961 cctcgaaggg cgtggcttga actcatcata tgccgtctat caggatgcta cgggtaaggc
     4021 ttttgacaag acgattgcac tgggtatcgg tatcggttcg ggatatttgt tcgagacaac
     4081 tttcatccgc gaagccactt ccgacttgac cggtgaacgc ggttcattga tgggtgctat
     4141 ccagggattg ctgttggctc agtatgaagt attgcgcgaa aacggtcaca ctccttctga
     4201 agcattcaat gaaactgtgg aagagttgac tcaatctttg atgccattgt ttgccaagaa
     4261 tggtatggac tggatgtatg ccaactgttc tactacggca cagcgtggtg cgctggattg
     4321 gatgaccccg ttccatgatg ccatcaagcc ggttgtacag aaattgtatg caagcgtgaa
     4381 gtcgggtaac gaagctcaga tttctatcga cagcaactcc aaacccgatt atcgtgagaa
     4441 gctgaatgca gaattgaaag cattgcgtga aagcgaaatg tggcagacag ctgttacagt
     4501 tcgtaaactt cgtccggaaa acaattaatc agctttatat aaataggtga aataccctct
     4561 tcggtgttac cggagggggt atttctttat tattgattcc ctatattttg aataaactcc
     4621 aatagcttcc ggtaaaaacc gtgatgtttc agcgtctctg cctctcccaa tatcaccagc
     4681 ttcatacgtg cccgggtgat ggctacattc attctcctta aatcattcag gaatcctatc
     4741 tgcccttctt cgttggcgcg gacaaggctg atgaagataa catcgcgctc ttgcccttgg
     4801 aagccatcca ccgtatttac agtgaacaag ctgcgataag gcttgagtga agcgtctgcc
     4861 tttatcttgt tgcggagata ttgcacttgt gccttgtaag gggagatgat gccgaagtct
     4921 attttttctt ccagaatgcg gctgccaccg atacggttga tgtagatttt cagttctgat
     4981 aggagcaggt ccgcttccgc tttattgatg cgtccgaaag tctctcccac aaattcttct
     5041 ttgaaatcca tttcggaggt gtcaatccag tggatagggg tatcccagtc caggatgccc
     5101 cggtaacgca cttcgggagc ggcttcca
//
