LOCUS       c00285_gnlPro..         3916 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KFFLNLJI_285.
ACCESSION   c00285_gnlPro..
VERSION     c00285_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 10:38:09
            Original ID  :: gnl|Prokka|KFFLNLJI_285
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 3916
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..3916
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[834:3916]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      835..3916
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="TPP_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..3916
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TPP_enzyme_C and not (PFL-like or
                     PFL_6_pcresol or PFL_9_tma or Gly_radical or Gly_430_pcre
                     or Gly_8-9_TMA or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (POR or POR_N or PFOR_II))"
                     /kind="single"
                     /product="TPP_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..3916
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="TPP_AA_metabolism"
                     /region_number="1"
                     /rules="(TPP_enzyme_C and not (PFL-like or PFL_6_pcresol or
                     PFL_9_tma or Gly_radical or Gly_430_pcre or Gly_8-9_TMA or
                     PFL_acetate1 or PFL_acetate2 or Gly_radical_scatole or
                     PFL_proline or PFL_toluene) and minimum(2, [ALS_ss_C,
                     AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG, Beta_elim_lyase,
                     CPSase_L_D2, Cys_Met_Meta_PP, ELFV_dehydrog, GRDB,
                     Glu_syn_central, Glu_synthase, Gly_reductase, HAAA1, HG2B1,
                     HG2B2, HGD-D, HleuD1, HleuD2, HleuS1, HleuS2,
                     Homoserine_dh, ILVD_EDD, IlvC, Lactoyl-CoA1, Lactoyl-CoA2,
                     Lyase_aromatic, MAAL_C, OKR_DC_1_5_lysine,
                     OKR_DC_1_5_ornithine, OKR_DC_1_7_arginine, OKR_DC_1_C,
                     OTCace, PALP, Proline_reductase, Sacchrp_dh_C, TPL,
                     Thr_dehydrat_C, TnaA, Urocanase]) and not (POR or POR_N or
                     PFOR_II))"
                     /tool="gutsmash"
     CDS             221..457
                     /locus_tag="ctg285_1"
                     /transl_table=11
                     /translation="MTKLSNIPAKETTAKTAKTRKTKTGPAKLKWDPTKPVQFTQEEIW
                     EHIHEIEKGPFLTLDEGFKRFEAWKQDLLKSRL"
     CDS             424..765
                     /locus_tag="ctg285_2"
                     /transl_table=11
                     /translation="MEARPTQKQVITSSLFWESYDNVYVQGLDLFGFYQAELYANKIKS
                     ILYELDQTYPYYPECRHLATKSRMYRNIILDSHLIIYRITEERIEVLDIVHSASSMRKI
                     KKTRNIHIE"
     CDS             complement(835..1878)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: IlvC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) IlvN"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg285_3"
                     /sec_met_domain="IlvN (E-value: 9.7e-48, bitscore: 150.6,
                     seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="IlvC (E-value: 1.3e-40, bitscore: 127.8,
                     seeds: 295, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQMNFGGVVENVMTREEFPLEKAREILKDETIAVIGYGVQGPGQ
                     SLNLRDNGFNVIVGQRQGKTYDKAVEDGWVPGETLFGIEEACDKATIIMCLLSDAAVMS
                     VWPTMKPYLTAGKALYFSHGFAITWNDRTGVVPPADIDVIMVAPKGSGTSLRSMFLEGR
                     GLNSSFAIYQDATGKAMDRTLALGIGIGSGYLFETTFIREATSDLTGERGSLMGAIQGL
                     LLAQYEVLRENGHTPSEAFNETVEELTQSLMPLFAKNGMDWMYANCSTTAQRGALDWMG
                     PFHDAIKPVVEKLYANVKCGNEAQISIDSNSKPDYREKLEAELKALRESEMWQTAVTVR
                     KLRPENN"
     CDS             complement(1928..2653)
                     /locus_tag="ctg285_4"
                     /transl_table=11
                     /translation="MEKVGLFHFVAEPYLMDFRGRVTLPMIGNYLIHAASSHAGERGFG
                     FNDMSERHTAWVLSRLAIEMKEYPTAFDKINLYTWIDEVGRLFTSRCFELADENGKTFG
                     FARSIWAAIDVETRRPTLLDIEALGKYIDERPCPIEKPGKIMPAENKAEGIPYSIKYSD
                     LDINGHFNSVKYIEHLLDLFDIDQFKTREIGRLEIAYQSEGKQGMPLTLHKAESAPDKQ
                     DMAICHEGKAICRAAVTWR"
     CDS             complement(2660..3214)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: ALS_ss_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg285_5"
                     /sec_met_domain="ALS_ss_C (E-value: 1.6e-17, bitscore:
                     52.4, seeds: 685, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTKKLYTVIIFSENIVGLLNQITIIFTRRQLNIETLSVSPSAIK
                     GIHKFTITTFADEDMIDKVVKQIDKRVDILKAYYNTDEDLVYQEIALYKLSTELFIKMG
                     TVEGLIRKYNARILEMNEACVVLEKSGHYDETQALFNELSETIGVLQFIRSGRVAITKS
                     KVERLSDMLADMERKLHEKQQ"
     CDS             complement(3230..3916)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_AA_metabolism: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg285_6"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.9e-52, bitscore:
                     164.5, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="KRPEWNAEFDRDEKEEYDKVIEKELYPTEGQLKMGEVVRKVSEAT
                     GNDAVLVTDVGQNQMMGVRYFKYKQTRSVVTSGGLGTMGFGLPAAMGAKFGAPDRTVCF
                     FTGDGGMQMTIQELGTIMQEKLNVKIIILNNNFLGMVRQWQELFFHERYSNTIMENPDF
                     VAIAKAYGIAGRAVEKREELDDAIAEMLNHDGAYVLVANVETCGMVYPMVPAGGSVTNM
                     IMGDEK"
ORIGIN
        1 ttattgtgcg tatatagcag ataagcgatt aaaaatagcg gttatgtgac ataaataaat
       61 ttgaatacca ttttgagggg atggagacgg ggcacgcccc gtctctacaa ctgggtaatg
      121 agttaatcct atagacctac ttttttcctt accaaatatc ttattacatg gaaattattc
      181 catacatttg ccacagtact aattaataac gattacgact atgacaaaat taagcaacat
      241 ccccgccaag gaaactacgg ccaagaccgc aaagacacgt aagaccaaga ccggacccgc
      301 aaagctcaag tgggatccca ccaagccggt gcaattcacc caagaagaga tctgggaaca
      361 tatccatgag attgagaagg gaccgttcct aaccctagat gaaggtttta aacgttttga
      421 ggcatggaag caagacctac tcaaaagcag gttataacca gtagtttatt ttgggaaagt
      481 tacgataatg tatatgttca aggccttgac ttatttggat tctaccaagc ggaattatac
      541 gctaacaaga taaaatccat cttatacgag ttagaccaaa cctatcctta ttatcccgaa
      601 tgccgacacc tagccacgaa aagccgcatg taccggaaca tcatcctaga ttcacacctt
      661 atcatctacc gcatcaccga ggaacgcatc gaggtgctgg acatcgtcca ttcagcatcc
      721 agcatgcgaa agatcaagaa gactaggaat atccacatcg aataacacaa agaaaggcga
      781 gccacccgta agtgacccgc ctctttttgc tgatatataa ggattaagat tggattagtt
      841 gttctccgga cgaagcttac gtacagtaac agctgtctgc cacatctcgc tctcgcgcaa
      901 tgccttcaat tcagcctcca atttctcacg ataatccggc ttagagtttg agtcgataga
      961 gatctgagcc tcgttaccgc attttacgtt tgcgtacaat ttctcgacaa ccggcttgat
     1021 tgcgtcgtgg aacggaccca tccagtccaa agcgccacgc tgggcggtag tagagcagtt
     1081 cgcgtacatc cagtccatac cattcttggc gaataaaggc atcaaggatt gagtcaactc
     1141 ctcgaccgtc tcgttgaaag cctcggaagg agtatgtcca ttctcgcgca atacctcata
     1201 ctgggccaac aacaaacctt ggatagcgcc catcaaggaa ccacgctcac cagtcaaatc
     1261 ggaagtagcc tcacggatga aagtcgtctc gaacaagtag ccggaaccga taccgatacc
     1321 caacgccaac gtacgatcca tcgccttgcc agtagcgtct tgatagatag cgaaagaaga
     1381 gttcaagcca cgaccctcaa ggaacatgga acgcaaagac gtaccagacc ccttcggagc
     1441 gaccatgatc acgtcaatat ccgcgggagg aacaacgccc gtacgatcgt tccaagtgat
     1501 cgcaaaacca tgagagaaat acagggcctt gccagctgtc aaataaggct tcatcgtagg
     1561 ccatacagac attacggcag cgtcggacaa caagcacatg atgatcgtgg ccttgtcgca
     1621 agcctcctcg ataccgaaca gagtctcacc cggaacccat ccgtcctcaa ccgctttatc
     1681 gtaagtctta ccttggcgct ggccaacgat tacgttgaag ccattgtcac gaaggttcaa
     1741 tgactgtccc ggtccctgta cgccatagcc gataacagcg attgtctcat cttttaatat
     1801 ctctcttgcc ttttccaacg gaaattcctc gcgggtcatt acattctcta caacaccgcc
     1861 aaaattcatt tgtgccattt tctttttaac tattaatgtt taaaaaccta tttatgtatc
     1921 tcttttatta tctccaagta accgccgcac gacagatcgc ctttccctca tggcaaatag
     1981 ccatgtcttg cttatcggga gcggactccg ccttatgaag cgtaagcggc ataccttgtt
     2041 taccctcgga ttggtaggcg atctccagac ggccgatctc acgggtcttg aactgatcga
     2101 tatcgaacaa atccagcagg tgctcgatat acttcacgct attgaagtga ccgttgatat
     2161 ccaagtcgct gtatttgatc gaatacggga ttccctccgc cttattctcc gccggcatga
     2221 tcttgcccgg cttctcgatc gggcacggac gctcgtcgat atatttgccc aatgcctcta
     2281 tatccaataa ggtaggacgg cgggtctcca cgtcgatagc cgcccaaata gaacgggcga
     2341 atccaaaggt tttcccattc tcatccgcca gctcgaaaca acgactggtg aagaggcgtc
     2401 cgacctcatc gatccaagtg tatagattaa tcttatcgaa ggcggtagga tattccttca
     2461 tctcgatagc cagacgggac aacacccaag ccgtatgacg ctccgacata tcattgaaac
     2521 cgaacccacg ctctccggca tggctggaag cggcgtgaat caaatagtta ccaatcatag
     2581 ggagcgttac acgtcccctg aaatccatca aatacggctc cgccacgaaa tgaaataatc
     2641 ctactttctc catatcttat tattgttgct tttcatgtaa ctttcgctcc atatcggcca
     2701 acatatcgct caagcgctcc accttgctct tcgtgatagc cacacgtccg gagcggatga
     2761 attgcaggac accgatcgtc tcgctcaact cattgaacaa ggcttgtgtc tcgtcatagt
     2821 ggccactctt ctccaacacc acgcaggcct cgttcatctc caagatacga gcgttgtatt
     2881 tacggatcaa tccctccacg gttcccatct tgatgaaaag ctcggtactt agcttataaa
     2941 gggcgatctc ttgataaacc agatcctcat ccgtattata ataagccttc aagatatcca
     3001 cacgtttatc gatctgtttc accaccttat cgatcatatc ctcatcggcg aaggtcgtga
     3061 tcgtaaactt atggatgccc ttgatagcgg acggagagac ggacagagtc tcgatgttca
     3121 gctgtcggcg tgtaaagata atcgttatct ggttcaaaag acctacgata ttctctgaaa
     3181 agataataac ggtatataat ttctttgttg tcatagcttc atctcctcct tatttctcgt
     3241 ctcccataat catgtttgtc acgcttcccc cggcaggaac catcggatat accattccgc
     3301 aagtctccac gttagcgacc aacacgtaag cgccgtcgtg gtttagcatc tcggcgatag
     3361 cgtcgtccaa ttcctcccgc ttttcaacgg cacggccagc gataccatag gctttagcga
     3421 tcgccacgaa atccggattc tccatgatgg tgtttgaata acgctcgtgg aagaacaatt
     3481 cttgccactg acgtaccata cctaagaagt tattattaag aatgataatc ttcacgttca
     3541 gtttctcctg catgatggta cccaattcct gaatcgtcat ctgcataccc ccatcaccgg
     3601 taaagaagca gaccgtacgg tccggagccc cgaacttagc gcccatagcg gccggcagac
     3661 caaatcccat cgtacctaaa cctccggaag tcaccacgct acgggtttgt ttatatttga
     3721 aatagcggac acccatcatc tggttctgcc caacgtcggt caccaataca gcgtcgttac
     3781 cggtcgcctc ggaaacctta cggactacct cgcccatttt cagttggccc tcggtcggat
     3841 acaattcctt ctcgattacc ttatcgtatt cctctttctc gtcccgatcg aactcggcat
     3901 tccattccgg acgttt
//
