LOCUS       c00737_gnlPro..         5372 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IIPHOEFF_737.
ACCESSION   c00737_gnlPro..
VERSION     c00737_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 11:04:39
            Original ID  :: gnl|Prokka|IIPHOEFF_737
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 5372
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..5372
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[681:5209]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      682..5209
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..5372
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..5372
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             2..553
                     /locus_tag="ctg737_1"
                     /transl_table=11
                     /translation="KIRYYGENCAKGYAMGLDVKFFGEFVPGTDSWISFSLMKAQQTIR
                     ETTTVPMANSQGYNISLFFQDYFPGYKRVKLNLKGVLSGGLPQTIPGKGYEAGYFRTPA
                     YKRVDIGLSYQLAGGTDAIMDRGFFRHLKNIWLGLDVFNILDIKNVSSYYWITDVYNVQ
                     YAVPNYLTGRQLNVRLIVDF"
     CDS             682..1092
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg737_2"
                     /sec_met_domain="Glyoxalase_4 (E-value: 1.3e-27, bitscore:
                     85.0, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTHIEHLGIAVKSIEACLPYYEGVLGLKCYNIEVVADQKVKTA
                     FFKVGQTKIELLEPTSEDSTIAKFIEKKGEGIHHIAFAVPDVQAALNEAEEKGVKLIDK
                     APRGGAEGLNIAFLHPKSTCSVLTELCMPGNK"
     CDS             1129..2682
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg737_3"
                     /sec_met_domain="CT_Btheta (E-value: 4.7e-293, bitscore:
                     960.6, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIALREQARLGGGEKRIESQHKKGKYTARERIAML
                     LDEGSFEEFDMFVQHRCTNFGIEKTKYLGDGIVTGYGTIDGRLVYIFAQDFTVFGGALS
                     EALAMKICKVMDQAMKMGAPVIGLNDSGGARIQEGVNALAGYAEIFQRNILASGVVPQI
                     SGIFGPCAGGAVYSPALTDFNIMTRGTSYMFLTGPKVVKTVTGEDVTQEQLGGASVHTT
                     KSGVAHFAVDTEEDGLQLIRKLLSFLPQNNLEETPLVECKDPIDRLDDVLNDIIPDNAN
                     QSYDMYEVIGTIVDNNEFLEVHADYAKNIIVGFARFNGQSVGIVANQPKVMAGCLDSNA
                     SRKAGRFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKITV
                     TLRKSYGGAYCVMSSKHLRGDMNYAWPTAEIAVMGPSGAVEVIFAKEVAAAEDPKACAA
                     EKEAEYRKAFANPYNAAQYGYIDDVIEPRNTRFRIIRALQQLQTKKLSNPAKKHDNLPL
                     "
     CDS             2704..3591
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg737_4"
                     /sec_met_domain="OAD_gamma (E-value: 1.4e-13, bitscore:
                     40.1, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINKKIGVLLLFALLISFGAKAQRATSMRINEVLVINEDNFVDDY
                     GKRHGWIELFNTSAGTVNIAGCYLTDDKNNPMKYPIPKGDVLTQIQPRQHTLFWADGQP
                     GRGTFHVNFVLDPSKENYIALYDADGKTLIDEVTIPAGQMADISYGRVIDGKDEWAQLK
                     KVTPSTNNLTLDSNEKIDNFKQNDSLGIGMTITAMAVVFLGLFLLYIIFKQIGRLSISA
                     SKRNAQKAAGTTSVSVDAGQESGEIFAAIATALYEMSDDNHDIEHTVLTIHKVQRTYSP
                     WSSKLYGLRQTPHK"
     CDS             3613..4044
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 64.8; E-value:
                     1.6e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg737_5"
                     /sec_met_domain="Biotin_lipoyl (E-value: 1.5e-21, bitscore:
                     64.8, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSFKYTINGNVYKVHINSVVDDIADVEVNGTPYQVKLEKPAKKQ
                     MVTLKRPAQAPTTASGDPVVTRPAASTTQGAVKTPLPGVILQVKCNVGDTVKRGQTLII
                     LEAMKMENNINADRDGKIIEIKVHKGDSVLEGADLVVIG"
     CDS             4049..5209
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg737_6"
                     /sec_met_domain="OAD_beta (E-value: 4.6e-154, bitscore:
                     501.2, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQESFLTFLGENLQLFLTYTGVYNATPGHLIMILVGLLFIFLAIK
                     YEFEPMLLIPIGFGILIGNIPFKDAGLQVGIYEQGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYTIALQMGFEPNQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPIIQPPFMRLLTTKKERLIRMKPPRAVSSTEKIIFP
                     IVGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLAETARGPLIDTITILLGITVGAS
                     TQATQFLTLNSIKIFGLGALSFVIATCAGVLFVKLFNLILKDGNKINPLIGNAGVSAVP
                     DSARISQVVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLG"
ORIGIN
        1 caagatccgc tattacggtg agaactgcgc caaaggttac gccatgggac tcgatgtcaa
       61 attcttcgga gaattcgtac cgggtaccga ctcatggatc agcttctcct tgatgaaagc
      121 ccagcaaacc atccgggaaa caacgaccgt tcctatggcc aatagccaag gctacaacat
      181 ctcactcttc ttccaagatt atttcccggg ctataaacga gtcaagctaa atctgaaagg
      241 agttctatcc ggaggacttc cccagacaat cccgggcaaa ggatacgaag ccggctattt
      301 ccgtacgccc gcctacaaac gtgtagatat cggcctctcc tatcaattgg caggaggcac
      361 ggacgctatc atggacaggg gcttcttccg ccatttgaaa aacatttggc taggtctgga
      421 tgtatttaac atattagaca tcaaaaacgt tagttcctac tattggataa cagatgtata
      481 taatgtccaa tacgcagttc caaactatct gaccggacgt caattgaacg ttcgtctgat
      541 tgtcgatttt taataaaatg tatctttaaa cacatttact gggagataaa aacaaaaaat
      601 tatttcctca ttcataaaaa gtagtgtaca tttgcacaca atagaaacaa acatttacta
      661 aatctttaaa ttattattga catggaactt acacatatcg aacatttagg tatcgcagtg
      721 aagagtatcg aggcttgttt accctattat gaaggcgttc ttggattaaa atgctacaat
      781 atcgaagtag tagcagacca aaaagtaaaa accgcatttt tcaaggtagg acagactaag
      841 attgaattac tagagccgac cagcgaagat agcacgatcg caaaatttat cgagaaaaaa
      901 ggtgaaggta tccaccatat cgcattcgcg gtacctgatg tacaggcagc tttgaacgag
      961 gctgaggaaa aaggcgttaa attaatcgat aaagctcccc gtggtggcgc ggaaggcttg
     1021 aacatcgctt tccttcaccc gaaatcaact tgcagcgtat tgacagagct ttgcatgccg
     1081 ggcaacaaat aattaatccg ttcatttcta acaacaaatc aaaatacaat gagtaaccag
     1141 cttgaaaaag taaaagagct catcgcactt cgtgagcaag ctcgcttagg tggaggagag
     1201 aaaagaatcg aatcacagca caaaaaaggc aaatataccg ctcgtgagcg tatcgccatg
     1261 ttgcttgacg aaggtagttt cgaggaattc gacatgtttg ttcaacaccg ttgtacaaac
     1321 ttcggtatcg agaaaactaa atatttaggc gatggtatcg taacaggtta tggtacgatc
     1381 gacggacgtt tggtatatat cttcgctcaa gatttcaccg tattcggtgg agccttgtct
     1441 gaggctttgg ctatgaagat ctgtaaagta atggatcaag ccatgaagat gggcgctccc
     1501 gttatcggtt tgaacgactc cggtggagct cgtatccaag aaggagtaaa tgccttggca
     1561 ggatacgctg agattttcca acgtaacatc ttggcttccg gtgttgttcc tcagatttcc
     1621 ggtatcttcg gcccttgcgc cggtggagcc gtttattctc cggctttgac agacttcaac
     1681 atcatgacac gtggtaccag ctatatgttc ttgactggtc cgaaagtcgt aaaaaccgta
     1741 acaggtgagg atgtaaccca agagcagttg ggtggagcca gcgtacacac taccaaatcg
     1801 ggtgtagccc atttcgctgt cgatacagaa gaagatggtt tgcaattgat tcgtaaattg
     1861 ctcagtttct tacctcagaa caacttagag gaaacgccgt tagttgagtg caaagacccg
     1921 atcgatcgtc tggatgatgt attgaacgat atcattcccg ataacgccaa ccaatcttac
     1981 gatatgtatg aggttatcgg tacgatcgtc gataacaacg agttcctaga ggtccatgcg
     2041 gactacgcta agaatatcat cgtaggtttc gctcgtttca acggacaatc cgtcggtatc
     2101 gtagctaacc agccgaaggt tatggcagga tgcttggata gcaacgcatc tcgtaaagca
     2161 ggtcgcttcg ttcgtttctg cgacgctttc aatattcctt tggtaacatt ggttgacgtt
     2221 ccgggattcc ttccgggcac aggtcaggaa tacaacggtg taatccttca cggcgctaaa
     2281 ttgctttacg cttatggtga ggctaccgtt cctaagatta ccgttacatt gcgtaagtct
     2341 tacggtggag cttattgcgt gatgagttct aaacatttac gtggtgatat gaattacgca
     2401 tggccgacag ccgagatcgc cgttatgggc ccgagcggtg ccgtagaggt tatcttcgcc
     2461 aaggaagtag cagccgctga agatccgaaa gcatgcgcag cagagaaaga agctgaatat
     2521 aggaaagcat tcgctaatcc ttataacgca gctcaatacg gttatatcga cgatgttatc
     2581 gaaccgcgta acactcgttt ccgtattatt cgtgctttac aacagttgca gactaagaag
     2641 ttaagcaatc ctgctaagaa acatgataac ctgcctctat aatccgtaaa acaggagatg
     2701 aatatgataa ataagaaaat aggggtattg ctactgttcg ctttgctcat ttcattcggg
     2761 gcaaaggcac agcgcgcaac ctccatgcgt attaatgaag tattggttat caacgaggat
     2821 aacttcgttg acgactatgg caaacgtcat ggctggattg agttgttcaa cacttcggcc
     2881 ggaacggtaa atatcgcggg atgttatttg acagacgaca aaaacaatcc gatgaaatat
     2941 ccgatcccga agggagacgt attgactcag atccaacccc gccagcacac actattttgg
     3001 gctgacggac agccgggcag aggtacattc cacgttaact tcgtattaga tccctctaag
     3061 gagaattata tagctctgta tgatgcagat ggtaaaacat tgatcgacga agttacgatc
     3121 cctgccggac aaatggctga tatcagttac ggtagagtga tcgatggtaa agatgaatgg
     3181 gcacagctga agaaagttac tcccagtacg aataacctaa cattggattc taatgagaaa
     3241 atcgataatt tcaaacagaa tgactcttta ggtatcggta tgaccattac cgctatggct
     3301 gtagtgttct tgggattatt tttgttatac atcatcttta agcagatcgg tagattgtct
     3361 atatccgcga gcaaacgtaa cgctcaaaaa gctgcgggaa caacaagtgt atcggttgac
     3421 gccggacaag agtctggtga gatctttgcc gctatcgcta ccgctttgta cgagatgagt
     3481 gatgacaatc atgacatcga gcacacggtt cttacgatcc acaaggtaca aaggacttat
     3541 tctccttgga gttcaaaact ctacggtttg cgtcaaaccc cacataagta attatctaaa
     3601 aacgaacaaa gaatgaaaag ttttaaatat accattaacg gtaacgtata taaagtacac
     3661 atcaattctg tagtggatga catcgcagat gttgaagtaa atggtacacc ttatcaagta
     3721 aaattagaga aaccggcgaa gaaacaaatg gttacattga aacgtccggc tcaagcaccg
     3781 acaacagcaa gtggcgaccc tgtagttact cgtccggcag cctctactac acaaggtgct
     3841 gttaagactc cgctgccagg tgttatcttg caggttaagt gcaacgtagg tgataccgtg
     3901 aagagaggtc aaacattgat tatccttgag gctatgaaga tggagaacaa catcaacgca
     3961 gaccgtgacg gtaagattat agaaattaaa gtacacaagg gagactctgt gctagaaggt
     4021 gctgatctcg tagtaatcgg ataagactat gcaagagagc tttttaacat tcttaggtga
     4081 gaacttacaa ctgttcctta cctatacagg tgtatacaac gctactccgg gacatctcat
     4141 catgattctg gtaggtctgt tgtttatatt cctggcgatt aaatatgagt ttgaaccgat
     4201 gcttttgatc cctatcggat ttggtatctt gatcggtaat atccctttca aggacgcagg
     4261 tcttcaggta ggtatttatg agcaagggtc tgtactgaac atcctctatc agggtgtgac
     4321 ttctggatgg tatccgccat tgatcttcct cggtatcggg gccatgaccg acttctccgc
     4381 attgatctcc aatcctaagt tgatgttgat cggtgcagcg gctcagttcg gtatctttgg
     4441 tgcttatacg attgctcttc aaatgggatt tgagccgaac caagcaggtg ctatcggtat
     4501 tatcggtggt gctgacggtc cgacggctat cttcctgtct tctaagttag cgccaaactt
     4561 aatgggtgcg atcgcggtat ccgcttactc atacatggcg ttggttccta ttatccaacc
     4621 gccgttcatg agattgctta cgactaagaa agagcgtttg atccgtatga aaccgccgag
     4681 agccgtttct tccacggaaa aaattatctt cccgatcgtt ggtttgttgc ttacttgctt
     4741 cttggttccg tccggtttac cattgttagg tatgctattc ttcggaaact tattgaaaga
     4801 aagtggcgtg actcgtcgtt tggcagagac tgctcgtggt ccgctgatcg atacaatcac
     4861 gatcttattg ggtatcacgg taggtgcttc tacccaagct acacagttct tgacattgaa
     4921 ctctatcaag atcttcggtc taggtgcgtt atcattcgtg atcgctactt gcgccggtgt
     4981 attgttcgtt aagttattca atttaatatt gaaagacggc aataagatca atccgcttat
     5041 cggtaacgcc ggtgtatccg ccgttcctga ctcagctcgt atctcacaag ttgtaggttt
     5101 ggaatatgac ccgaccaact acttgttgat gcacgctatg ggtccgaacg tagcaggtgt
     5161 aatcggttcc gctgtagctg ccggtatctt gctaggattc cttggttaat aaaacaacta
     5221 tctatattaa aaaaggcgag gtccgaaagg atcccgcctt tttatgttat tgttctcagt
     5281 tagtttgctc tataggaacc ggagtaatct ccgtactcgt atcctccacc aacgttgtcc
     5341 cgaggaacaa ccagatcatc aaaaggatta ta
//
