LOCUS       gnlProkkaIEJKEJCD_95   13296 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IEJKEJCD_95.
ACCESSION   gnlProkkaIEJKEJCD_95
VERSION     gnlProkkaIEJKEJCD_95
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-02 01:41:49
            Original ID  :: gnl|Prokka|IEJKEJCD_95
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13296
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13296
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3568:3835]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3569..3835
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..13296
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13296
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             3..659
                     /locus_tag="ctg95_1"
                     /transl_table=11
                     /translation="MGFTCPEGRTKPWGTNHAVMMGADVIQEPFAVINCDDFYGRDSFQ
                     VMGKFLAALPEGSKNVYSMVGFRIGNTLSESGTVSRGLCGTDANNLLTSVVERTKIQRM
                     DGEVKYIDDNGEWTATPETTPVSMNFWGFTPDYFAYSAEFFKSFLSDPKNMENLKSEFF
                     IPLMVDKLINDGTATCEVLDTTSKWFGVTYPEDRQSVVDKIQALVDAGEYPAKLF"
     CDS             complement(704..2374)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 275.5; E-value:
                     1.5e-83)"
                     /gene_kind="transport"
                     /locus_tag="ctg95_2"
                     /transl_table=11
                     /translation="MKKQQKDKKVKKDRREKLRYIREVSAEQRGRILLSCLTGILGVAF
                     ALAFIYATKRVIDTATGITDDNLTHVAVLTVVLLTAQLLCGAADTWISTRMQIETGNAL
                     RHRLFSRLLQSRWNELERFHTGDVVNRVEQDTAAIVTLLTSSVPAFIVTSIQLLAAFLF
                     FYFLDPSLPWLIVAILPVFLLGSRFYMRRMKRYTHDIRNSDGRIQSVIQESLQHRIVIK
                     TLEQGERHLDKLDDLQDMLHSQVMGRTRFSLSAHMLVALAFSGGYLTAFLWGAVHLSAG
                     CITFGTMTAFLQLVGKVQRPVLDLSRLIPSVVNALTAIDRLLELERLPAEADGDSIFLA
                     STPELELKDVTFGYTPDDRPVFSRFSCRFPAGSCIAVVGETGKGKTTLIRLLLALATPQ
                     EGQILLIPAKHPLETSHTVSPQTRKNFVYVPQGNTLFSGTIRDNLLMGNPQASEEAIYQ
                     ALQTATADFVFHLPDGVDSPLSERGGGLSEGQAQRIAIARALLRPGNILLLDEATSALD
                     PDTERLLIKNLRRDCAGKTCIFVTHHPAVAEACESIVRL"
     CDS             complement(2397..3560)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg95_3"
                     /sec_met_domain="NTP_transf_5 (E-value: 9.8e-47, bitscore:
                     149.3, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQHAFFSLVRSGLWGTPADRQLFRSVSPDDWETVYRMANSQALLA
                     LTFDGISSLPAELRPPRALYLKWAARTAQIEQANKRLNQLLPELNTLYREAGLHPVLLK
                     GQGIGTNYRTPLHRQCGDIDIYLGKQGQPIANRLLLQQGAIVEGEASDKHASYSLKGVH
                     IENHRIILRLNSPLANRHFQQIIRKWYPQETDYALFSETGKEDSKAVSIAIPPATFNAL
                     YIFLHAFVHFLNSGIGLRQLCDWTCLLANRHKEIDATTLLRQLQDLGLLHAAQAFGYIA
                     VTRLGLPANRLPFPLEGTKQIGEQLLEDILSTGNFGQHDNRIKPRPKGYWAGKWYTFCR
                     ATRRCNELRQFAPYEALWYPVTLIGGTIAIQINRLKGVKDKKARTKK"
     CDS             complement(3569..3835)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg95_4"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1e-13,
                     bitscore: 41.0, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 4.8e-16, bitscore: 48.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKQGFILHRIGDDYIIMQDGSSNVDFSKVISLNQTSAMLWQEI
                     ENKEFDTDSVTEALTSRYDVDNESARRDAQKFIDSLDREGIIE"
     CDS             complement(3848..4288)
                     /locus_tag="ctg95_5"
                     /transl_table=11
                     /translation="MKKSIPNEILLPEVARLIKEGHTVTITVRGNSMNPFLVDRRDRVT
                     LGDFTTEQLQPGVAVLARDLTERIVFHRIIRRNGNILILQGDGNLAQTEETDIGRVMGV
                     MTEAMRKDKRYTADGKVWKLYSYWWMKLNPARRWLLALFRRI"
     CDS             complement(4315..5241)
                     /locus_tag="ctg95_6"
                     /transl_table=11
                     /translation="MRIQILDYQVGPHTFRMVKPSDFNIFKALPSLIPFITTIDTTQKV
                     IFETEIDDDETATKRTIAKTPDDICFNWEDADCIIRPLPHSSHLVSITPRKSGKNYWME
                     CNDNFRQCFIHLPACRTETPAPENETNFVLNNFLMMLYAFNAARHHTLLMHASVVATET
                     GKGYLFLGKSGTGKSTHTGLWLQQFSDCHLLNDDNPIVHVDSLGKQATVFGSPWSGKTP
                     CYRKESMTVGAFVRLEQAPQNEIEQERAAHAFATLLPSCSCLKQNKEIYNAIVTTVTEL
                     ATLAPVYHLKCLPDREATELCRKTVEG"
     CDS             complement(5488..9066)
                     /locus_tag="ctg95_7"
                     /transl_table=11
                     /translation="MMKLRNLMQVACMATAALTAFSCSQEEFENSGWKGNITVNATFEG
                     AGTDTRTTVNDEYKILWQDTDALGLFCSNAESNYSNTKLEYASGAGQTSATFNGSKPSG
                     ETAVFSIYPYQQNMSVSGNTLTMTLPATLTNYNGSSNGPMYAKVTNPDNLSALSFKHMA
                     AMIKLTVNKIPAEATTFKIIASNNIAGTCTVDLTAADPILAVTSDESKEITASFTASAD
                     IKSRNFYIPLPTGTYSSITAQLTNGSDKVYFTKTLNDKILGRRDILVVPPLDCVVVEAT
                     TPSALSTALADSKNLPQEAPTAATVTDIAVSGSFNTTSGSNDGIAIPVLQNSDINLAFN
                     TAPTTSTSAPLKLTDKTNTSVSTPAATATNSVSLAVPETTAEQEAPSVAITMPSTTVTL
                     AAVGNKATYNEVTATTAQQTLIINAGVTVKKLTVKGGNLKIYGKVEQLVHDAGNTTIYI
                     IKGTEASLPATIDSKFVVQSDVAVLKTAFANGEDFKLSADADITGQSVSVPAGKSVVLD
                     LNGYTLTADNSATGKIIVLGKMTLKDSSTEKKGKIVASQDYTAASYNGSLIEIAGEDAS
                     MTMESGNISAVRKTPNSNGQYGVGVTDGGDFTMTGGKIEAGWFAVAGNGNYKTQNSIIN
                     ITDGELISTADYAVYLPQSGTTTISGGKVYGAAGGVCIQRGTLNVEGTALITSKGTGST
                     GNWGDGTGGLDCAAINVSGAYGIATVNIKGGTLIAEAKSLITEGTTYTPVINVTGGTFS
                     DPSALKYMKTNANVNIKLTADKTCPGFKTTSGQTLTMDLGGKILTLADPTVGSTGTETN
                     SCQLLEGSNVTFKNGTLKSDNNKIMIQNYCNLTLDNMTVEDTNAQYVVSNNCGNISINN
                     TTINAGSNANQFAFDVCGYAKYTAGVTVTVSGTSVINGKVEISKSAGNTEPMKLNITGG
                     TFNGDLKVDASVGTENAKSIISVSGGTFSDPSVLKYMATNATVDIKLLSNINIAKTELA
                     TGYILNAANATANLNLNGHDIINSSETADATPFTQIFTVQNGTLNISGNGNVKCDASAT
                     AKDDGYRMVIEARGHGTVNIHGGSYYNTQKLNTQIDLIYARENGKINIYGGTFESGKYG
                     TPNNDTDGRYWVLNLKNTDKNTASIQVSGGTFINFNPANPNMDDNESYLVTGYEVTRDG
                     SVYTAAHKVNDGRKEYIVGPTSQENR"
     CDS             complement(9080..9295)
                     /locus_tag="ctg95_8"
                     /transl_table=11
                     /translation="MKQNTPDGREAYITPSIEVIKMENEGVIATSGEPYHPITRSYSGS
                     TSTHSYNSASSSDLEDLINDILTVEN"
     CDS             9344..9517
                     /locus_tag="ctg95_9"
                     /transl_table=11
                     /translation="MFVYPLFRPSHCPFPGYTTVTHVVCVYTIPPDGRKPYKHRREHPC
                     CYLQGNFQSCEV"
     CDS             complement(9661..9987)
                     /locus_tag="ctg95_10"
                     /transl_table=11
                     /translation="MKNCYGIDFRSWHKELRTREKTKQPPCKLPDRASRSLQGVLFKVY
                     QISVLILLKKILFSFFSVCLPLFIRHIAAMLLRKTSSKTMQTVTKYLKELSGVRSDNSP
                     NSYK"
     CDS             10853..11185
                     /locus_tag="ctg95_11"
                     /transl_table=11
                     /translation="MKQLIACCGLDCENCAARIATVNNDDELREKTAKEWSVLNNTPEI
                     TAETIHCMGCRADGVKFTYCSDYCAIRKCVYEKGFNTCGDCKELDTCQVVGAVLQHAPG
                     ARENLY"
     CDS             11420..12196
                     /NRPS_PKS="Domain: oMT (51-145). E-value: 2e-11. Score:
                     34.4. Matches aSDomain: nrpspksdomains_ctg95_12_oMT.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 81.3; E-value:
                     1.3e-24)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg95_12"
                     /transl_table=11
                     /translation="MSNENKTIHDFEFNLICDFFSNMERQGPGSPEVTLKALSFVDGLT
                     DESLIADIGCGTGGQTMVLAGHVPGQITGIDLFPGFIDIFNRNARQLGLQDRVKGIVGS
                     MDALPFGEEELDMIWCEGAIYNIGFERGLKEWRKYLKPGGYIAVSESSWFTDERPAEIN
                     DFWMDAYSEMDTLPNQVTKLYKAGYLPVATFILPENCWTEHYFASKVAAQEIFRKKYAG
                     NKIAEEFSLLQMIEDELYGKYKEFYGYVFFIAKKVG"
     aSDomain        11573..11854
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg95_12_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="2.00E-11"
                     /label="ctg95_12_oMT.1"
                     /locus_tag="ctg95_12"
                     /protein_end="145"
                     /protein_start="51"
                     /score="34.4"
                     /tool="antismash"
                     /translation="DIGCGTGGQTMVLAGHVPGQITGIDLFPGFIDIFNRNARQLGLQD
                     RVKGIVGSMDALPFGEEELDMIWCEGAIYNIGFERGLKEWRKYLKPGGY"
     CDS             complement(12271..13119)
                     /locus_tag="ctg95_13"
                     /transl_table=11
                     /translation="MNISEFNINDEFIACNHITTNELNPLVEKPYHTKASIFALCTKGV
                     LKTIINHTQFRVEANALLVIPPETFVQLLHTSDDAEIYVVIFSQQLIQSSGAGKVMMDK
                     FHIIGKHYIFPLSRTDFQLYAEFMTYLSHLYQRTESPSSLVSLQTLLTYLLQGISELCP
                     ERPRIKETPGSRHFNQYRIFIRLVHTDYVREHQVSYYALKMNMRPAALCRLVKKESGYT
                     AMEIINNTIIMDAKAQLCTANTPIKDIAVSLGFNNAAFFNKFFKRHTGIPPQKFRTSSK
                     Q"
ORIGIN
        1 ccgaaggctt cacttgcccc gaaggccgta ccaaaccttg gggaaccaac catgctgtaa
       61 tgatgggtgc cgatgtaatt caggaaccgt ttgctgttat caactgcgac gatttctacg
      121 gtcgtgattc cttccaggta atgggtaaat ttcttgcagc ccttcccgaa ggctccaaaa
      181 acgtatattc catggtaggc ttccgcatcg gcaacacgtt gagcgaaagc ggtaccgtat
      241 cccgtggatt gtgcggaacg gatgcgaaca acctgctgac ttccgtagtg gaacgcacca
      301 agattcagcg catggacggt gaggtgaaat acatcgatga taacggtgaa tggactgcca
      361 ctcccgagac gactccggtc agcatgaact tctggggttt cactcccgat tactttgctt
      421 acagtgcaga gtttttcaag agtttcttga gcgacccgaa gaacatggag aacctgaaga
      481 gcgaattctt catcccgctg atggtggata agctgattaa cgatggcact gctacctgcg
      541 aagtgctcga cacaaccagc aagtggttcg gtgtgactta tcccgaagac cgtcagagtg
      601 tagtcgacaa gattcaggct ttggtggatg caggcgagta tcctgcaaag ctgttctgag
      661 tttgttaacc aaaggcagat acccgttggg gctcattctc tgattataat cggacaatag
      721 attcgcatgc ctccgctact gccggatggt gggtgacgaa gatacatgtt ttgcctgcgc
      781 agtctctgcg caggtttttt attaacagcc gttccgtgtc ggggtcgagg gcagaagtgg
      841 cttcatctaa aagaagaatg tttccggggc gtagcagagc gcgggcaatg gcgatgcgtt
      901 gggcttgtcc ttcactgagt ccgccacctc gttcgctgag tggggagtct acgccgtcgg
      961 gaaggtggaa gacgaagtcg gcggtggcgg tttgcagggc ttgatatatg gcttcttcag
     1021 aagcttgtgg gtttcccatc agcaggttgt cacggatagt tccgctgaaa agggtattgc
     1081 cttgcgggac atatacgaag ttcttgcggg tttgcggaga gacggtatga ctggtttcaa
     1141 gtggatgttt ggcgggtatc aagagtatct gtccctcttg tggcgttgcc agtgccaaca
     1201 atagccggat gagcgttgtc tttccttttc ctgtttctcc gactacagct atgcagctac
     1261 cggcggggaa acggcaggag aagcggctga ataccggacg gtcatcggga gtgtagccaa
     1321 aagtcacgtc tttcagttcc agttccgggg tagaggcgag gaatatgctg tcaccgtccg
     1381 cttctgccgg cagtctttcc aattccaata gccggtctat ggcggtaagg gcattgacta
     1441 cggaaggtat caggcgtgag aggtcgagca cgggacgctg gacttttcct accaattgca
     1501 aaaaggcggt catcgttccg aaggtgatac agcctgcgct gaggtgaacg gctccccaaa
     1561 gaaaagccgt gaggtatccg ccggaaaagg caagggccac taacatgtgg gcggaaagcg
     1621 agaaacgggt acgtcccatg acttggctgt ggagcatgtc ttgcaagtca tcgagtttgt
     1681 ccagatgccg ttcgccttgt tccaatgttt taatcactat gcgatgttgc aggctctctt
     1741 gtatgacgga ctggatgcga ccgtcactgt tccgaatatc atgtgtatag cgtttcattc
     1801 gtcgcatata gaaacggctg cctaatagaa agacgggcag gatggcaaca atcagccatg
     1861 gcagtgaagg gtctaaaaag tagaagaata gaaaggctgc cagcagttgt atactcgtga
     1921 cgatgaatgc cgggacagaa gaggtgagca atgtgacgat ggcggcggtg tcttgttcta
     1981 cccggttcac tacgtctccg gtatggaaac gctccaattc gttccagcgg ctttgcagta
     2041 agcgcgagaa gaggcggtgg cgaagggcgt tgcccgtctc tatctgcata cgggtactta
     2101 tccaagtgtc agcagctccg cacagtaatt gggcagtcag caggacaacg gtgagaacgg
     2161 cgacatgcgt caggttgtcg tctgttattc cggtagcggt gtctatcacc cgtttggttg
     2221 catagataaa ggctagggca aaggccacgc ccagaatgcc ggtgaggcaa cttagcagga
     2281 tacgtccgcg ttgttcggca gatacctctc gaatatacct aagtttttca cgtctgtcct
     2341 ttttcacttt tttgtccttc tgttgctttt tcattccttt tattttccgg gttcttttat
     2401 ttctttgtcc ttgctttctt gtcttttact ccttttaatc ggtttatttg tatagctatc
     2461 gttcccccta tcagagtcac gggataccag agtgcttcgt acggtgcaaa ttgacgcagt
     2521 tcgttgcagc gtcgggtggc gcggcagaag gtgtaccact ttcctgccca atatcctttg
     2581 gggcgtggct tgatgcggtt atcatgttgc ccgaagttac cggtagacag gatgtcttcc
     2641 aataattgtt ctcctatctg cttggtgcct tccaagggga aaggaagccg gttggcgggc
     2701 aatcccagtc gggtgacggc aatgtagccg aatgcttgtg cggcatgcaa tagtccgagg
     2761 tcctgcaact ggcgaagcag ggtggtggca tctatttctt tgtggcgatt ggcaagcaga
     2821 caagtccagt cgcatagctg gcgcaggccg attccgctgt tcaggaaatg tacaaaggca
     2881 tgtaggaaga tataaagtgc attgaaggtg gccggaggta tggcgatact gacggccttc
     2941 gagtcctctt tcccggtttc ggagaatagg gcatagtctg tttcctgcgg ataccatttt
     3001 ctgataatct gctgaaagtg ccggttggca agcggactgt tcagccggag gatgatgcgg
     3061 tggttctcga tgtgtactcc tttcaaactg tagctggcat gcttgtcgga cgcttctccc
     3121 tcgactatgg cgccttgttg cagcaggagg cggttggcta tgggttgtcc ttgttttcct
     3181 aaatagatgt cgatgtctcc gcattgccgg tgcaagggag tgcggtagtt ggtgccgatg
     3241 ccttgccctt tcagcagtac gggatgcagc ccggcttccc ggtaaagggt attgagttcg
     3301 ggcagaagct ggttgaggcg tttgttggct tgttctatct gtgcagtccg ggcagcccat
     3361 ttcagataga gggcgcgtgg agggcgcagt tcggccggta gactgcttat gccgtcaaaa
     3421 gtcagtgcaa gcagggcttg tgagtttgcc atgcggtaca cggtttccca gtcgtccggc
     3481 gagaccgacc ggaagagttg tcggtctgcc ggagtgcccc acaggccgga gcgtaccaat
     3541 gaaaagaaag cgtgttgcat atccgtcctt attctatgat tccttcgcgg tcaagggagt
     3601 cgataaactt ctgcgcatcg cgacgggccg attcgttatc tacatcatag cggctggtca
     3661 gggcttctgt cacgctgtct gtatcgaact ctttgttttc tatctcttgc caaagcatgg
     3721 cggaagtttg gttcaggctg atgactttgc tgaagtccac gttcgacgag ccgtcttgca
     3781 tgatgatgta gtcatcgcct atccggtgca ggataaatcc ttgtttgatt ttcatggtta
     3841 ttttgtttta tattcttctg aacagggcga gcagccagcg gcgagcaggg tttagcttca
     3901 tccaccagta ggagtagagc ttccagactt tgccgtcggc ggtgtaccgt ttgtcttttc
     3961 gcatggcttc ggtcatgacg cccattaccc gtccgatgtc ggtttcttcg gtctgggcga
     4021 ggttgccatc gccttgcagg atgagtatat ttccgttccg acggatgatg cggtgaaaga
     4081 cgatgcgttc cgtcaggtcg cgtgccagta cggcgacgcc cggttgcagc tgttctgtgg
     4141 tgaaatcgcc cagtgtcacc cggtcacggc ggtccactaa gaaaggattc atgctgttgc
     4201 cccgcacggt gatggttact gtatgcccct ctttgatgag acgcgccact tcgggaagca
     4261 atatctcgtt gggaatgctt ttcttcatcg gctgttcagt tcatcattca taacttatcc
     4321 ttctaccgtc tttctgcaaa gctccgtcgc ttcacggtcg ggcaggcatt tcagatgata
     4381 gacgggtgcc agcgtggcaa gttccgtcac agtggtgaca atggcgttat agatttcctt
     4441 gttctgcttc aggcaagagc aggaggggag gagggtggcg aaagcatgtg ctgctctctc
     4501 ttgctctatt tcattctgcg gtgcttgttc caagcggacg aaggcgccta cggtcatgga
     4561 ttctttccga tagcatggtg tctttccgct ccacggagaa ccgaaaacag tggcttgctt
     4621 gccgaggctg tccacatgta ctatcggatt gtcatcgttc agtagatggc agtccgagaa
     4681 ctgttgcagc cagagcccgg tgtgcgtact tttgcccgtg ccgcttttcc ctaagaagag
     4741 gtagcctttg cctgtttcag tagcgacaac cgaggcatgc atcagcagtg tatggtggcg
     4801 ggcggcattg aaggcataga gcatcatcaa gaagttgttc agtacgaagt tcgtttcgtt
     4861 ttccggagcc ggtgtttctg tcctgcaggc cggtaggtgg atgaagcatt gcctgaagtt
     4921 atcgttgcac tccatccaat agtttttccc gcttttccgt ggggtgatgg atacaaggtg
     4981 tgagctgtgg ggcaaagggc gaatgatgca atcggcatct tcccagttga aacatatatc
     5041 atcgggagtt ttcgctatgg ttcgttttgt cgctgtttcg tcatcgtcta tctctgtttc
     5101 aaagattact ttttgcgtcg tgtctattgt cgtgatgaac ggaatcagtg aaggcaacgc
     5161 cttgaatata ttgaagtcgg aaggtttcac catgcggaag gtgtgcggtc ctacttgata
     5221 atccaatatc tgtattctca tatgttttga ttgttagttg ttattcatga tactttgggc
     5281 tactcagaaa aataatgaat gtttgtgtga atgaggaaga tttgagagat ttttcaactg
     5341 tcttgttgtc attttttaga cgcggaggac gcagatttat aaaagaaaat ccgctgtccg
     5401 ccgcatctaa aagatagtaa taaggcgatt ccgatacctc ttcgtttggt ctgcgaggat
     5461 atattgcttc ctttcttaga atttggctta tcggttctcc tgacttgttg ggccaacaat
     5521 atattctttc ctcccatcgt tgactttgtg ggctgctgta tatacactgc cgtcacgggt
     5581 aacctcgtaa cctgttacca aataggattc attgtcgtcc atattcggat ttgccgggtt
     5641 gaaattgatg aacgttccac cggacacctg gatgctggca gtgttcttgt ctgtattctt
     5701 taagttcagt acccagtatc tgccatccgt gtcgttgttg ggtgtaccat atttgccgga
     5761 ttcaaatgtt cctccataga tattgatttt cccattctct cttgcataaa tcaggtctat
     5821 ctgggtgttc agtttctggg tgttatagta agaaccgcca tgaatattta ctgtcccgtg
     5881 tcctcgggct tcaattacca tgcgataacc atcgtctttc gctgtagcag atgcatcgca
     5941 cttcacattg ccgttgcctg aaatgtttag tgttccgttc tgtacagtaa agatttgtgt
     6001 gaaaggagtg gcatcagctg tttctgagga attgatgatg tcgtggccat tcaggtttaa
     6061 gtttgccgtt gcgtttgcag cattcaatat gtagcctgtg gcaagctccg tcttggcgat
     6121 gttgatattt gagagaagtt ttatatccac agttgcgttg gttgccatgt acttcagtac
     6181 gcttgggtcg gagaatgtac ctccggaaac agagatgata cttttggcat tttcggttcc
     6241 cacggatgca tctaccttta agtcaccgtt gaaagtaccg cctgtgatat tcagcttcat
     6301 aggttcggta tttcctgcac tcttggaaat ttccactttt ccattgatga cgctcgtacc
     6361 gcttaccgta accgtgactc cagcagtgta ctttgcatag ccgcatacgt cgaatgcaaa
     6421 ttgattcgca ttgcttcctg cgttgatagt ggtattgttg atgcttatat tgccacaatt
     6481 gttgcttact acgtattggg catttgtgtc ttctactgtc atattatcta atgtcaggtt
     6541 gcagtagttc tgaatcatga ttttgttgtt gtcactcttc agcgttccgt tcttgaaagt
     6601 aacgtttgaa ccttcgagta attgacagct gttcgtttcg gtgccggtgg aacctacggt
     6661 cgggtcagca agtgtaagga tcttgccgcc taagtccatc gtcaaggttt gtccgcttgt
     6721 ggtcttgaat cccgggcagg tcttgtcggc ggtcaacttt atgttcacat ttgcatttgt
     6781 cttcatgtac ttcagcgcgc ttgggtcgga gaatgtaccg ccggtaacgt tgatgaccgg
     6841 tgtataagtg gtgccttctg tgatgagtga ctttgcttcg gcaatcagtg taccgccttt
     6901 gatgtttact gtggcaatgc catatgctcc acttacgttg atggcggcgc agtccagtcc
     6961 tccggtaccg tcgccccagt tgccggtgct gcctgtgcct ttactggtaa tcaaggctgt
     7021 gccttccacg ttcagagtgc ctcgttggat gcatacacct cctgcggcac cataaacctt
     7081 gccgccactg atggtcgttg tgccggattg gggcagatag actgcatagt cagcagtaga
     7141 aatgagttct ccgtctgtga tgttgatgat ggagttctgc gtcttgtaat tgccgttgcc
     7201 tgccactgca aaccatccgg cttctatctt gccgcctgtc atggtgaagt ctccaccgtc
     7261 cgtcactccg acgccatatt ggccgttact gttcggagtc tttctgactg cactgatgtt
     7321 gccgctttcc atggtcatgg aggcatcttc accggctatt tcaatcagac tgccattata
     7381 agaagccgct gtataatcct ggctggcaac tatcttgcct ttcttctcgg tagagctgtc
     7441 cttcagtgtc atcttgccca agacgatgat tttgcctgtt gcgctgttgt cggcagtcag
     7501 tgtatatccg ttcaagtcaa gaaccacgga ctttccggcg ggtacactga cgctttgccc
     7561 tgtgatgtcg gcatcggcgg acaatttaaa atcttcgccg ttggcgaaag cggtctttag
     7621 gactgccacg tcggattgaa ctacaaattt gctgtcgatt gttgccggaa gtgatgcttc
     7681 agttcctttt attatataga ttgtggtatt gccggcatcg tgtaccaatt gttctacctt
     7741 tccatatatc ttcaagttac cgccttttac ggtcagcttc tttacggtga cgcctgcatt
     7801 gataatcaat gtctgctggg cggtagtggc agtcacttca ttgtaagtgg ctttattgcc
     7861 tactgctgcc aatgtaacgg tggtgcttgg catggtgatg gctacagaag gagcttcttg
     7921 ctctgctgtg gtttccggca cagccaagga tacactgttg gtggcagtgg cggcgggagt
     7981 acttacgctg gtattggtct tgtcggtcag ctttaacggg gcagaagtgc tggttgtcgg
     8041 ggctgtattg aacgccaggt tgatgtccga gttctgtaaa accgggatgg cgatgccgtc
     8101 gttgctgcca gaagtggtat tgaagctgcc gctgactgca atgtcggtta cggttgctgc
     8161 tgtcggtgct tcttgtggga gattttttga atcagctaaa gctgtactaa gcgcactggg
     8221 ggttgtagcc tctaccacaa cgcaatccaa aggaggtact accaatatgt ctcttctgcc
     8281 taggattttg tcattaagcg tcttggtaaa atataccttg tcgcttccat tcgtcagttg
     8341 ggcagtgatg gaactataag tacctgtggg caaaggaatg tagaagttgc gagactttat
     8401 atcagctgag gctgtgaagg aggcggtgat ttccttgctt tcatcgctcg ttactgccag
     8461 tatcgggtct gctgcggtta agtctaccgt acaagtacct gcaatgttat tggaggcaat
     8521 aatcttgaaa gtagtggcct ctgccggaat cttgttgacg gtcagtttta tcatggctgc
     8581 catgtgcttg aaggacagag cgctcagatt gtcgggattt gtcaccttgg catacatcgg
     8641 gccattgctg ctgccgttat aatttgtaag cgtggcaggt agagtcatgg tcaatgtatt
     8701 gccgcttacg ctcatgtttt gttggtaagg atagatggag aatacagccg tttctccgct
     8761 tggcttgctg ccgttgaaag tggcggaagt ttgaccagca ccgcttgcat attctaattt
     8821 tgtattgcta taattacttt ctgcattact acagaacaac cctagggcat cggtatcttg
     8881 ccatagaatc ttgtattcat cgtttacggt agtacgggtg tcggtacctg cgccttcaaa
     8941 cgttgcgtta acggtgatgt ttcctttcca cccgctgttt tcaaattcct cttggctgca
     9001 actgaatgcg gtcaaggcag cagttgccat gcaggcaact tgcataaggt ttcttaattt
     9061 catcataatg aagtccccct tagttttcta cggttaagat gtcattgatt aggtcttcca
     9121 agtcgctgct ggatgccgaa ttgtagctat gggtagaggt gctgcccgaa taggagcgcg
     9181 taatgggatg gtaaggttcg ccgcttgttg caatgactcc ttcattctcc attttgataa
     9241 cttcgataga cggagtgatg tatgcttctc taccgtctgg tgtgttctgt ttcatataca
     9301 caaattattt aaaggttaaa caataaaaaa aacgtgagta actatgtttg tatatccttt
     9361 attcaggcct tcgcattgcc ctttccctgg atatacaaca gtcactcacg tcgtttgtgt
     9421 atatactatc ccccctgatg ggagaaaacc atataaacat agacgtgagc atccttgttg
     9481 ttatcttcag ggaaattttc aaagttgcga agtttgaata aagaagataa tttcaataat
     9541 gctcttacta atatgtaaat aaacccacta cgctatagcg gatttgtgac aaagataatt
     9601 gttttttgtt taagtgtatc tatgtttctc tatttttttt gggaaaggct cacgtctctt
     9661 tcatttatag gagttaggag agttatcact tctaactccc gataactcct tcaaatattt
     9721 agtaactgtc tgcattgtct ttgaggatgt ttttctgagg agcatagcgg ctatgtggcg
     9781 aataaagagg ggaagacaga ccgaaaagaa gctgaataaa atctttttaa gcaaaattaa
     9841 aacagagatt tgatatactt taaacagaac accctgcaaa ctccggcttg ctctgtccgg
     9901 cagtttgcag ggtggctgct tggttttctc gcgtgtacgt agctccttat gccacgaacg
     9961 gaagtcgatg ccatagcaat ttttcataat aagactttcc atatttttgc aaatgtccgt
    10021 actgcctttg gctgaaacaa tttatataag taattgaagt ttcgtaagtg agtatgcctg
    10081 ctgataaatg ggaatttatc gcacagagcg cgaagcctgc tctcataacc tatggagagc
    10141 acgagtgaaa gcttgtggat ttttatctaa aacataggta ttcctttact cttctccctt
    10201 tgtttgtctg ctgtggcata gggaatttat gacgcctaac ggccatgaac aaccctgctt
    10261 tcgaccataa agcaatcgtt tgacgaccgt aagcagagtt gttcatggcc gttaggcgtc
    10321 actaactcca aggcttttac agatgaagta cgtagcccga acctattgcg cacaaggcgc
    10381 aaacgtatta tacaacggtg taaaagacat tagagtgcat tattcatagt cggcctttga
    10441 ttcccgataa ctcctactat gctcctacag tccaactcca tatccgttga cttcacagta
    10501 aggacaagcc cgaaaatgca ggaaaaccga acctgccgat tcatgtaatc tgcatgcagt
    10561 attatgctag gggatagcag cttactgcaa aactcaggcg tttcaggcag gtggaagcaa
    10621 attttgcttc caccttttca ggttgcttcc atcgcagggc aaatgccgat ggacaggggg
    10681 atgcaggagg tgggtggaag tgtggaagca aagtgatgga aaattaattt ggcattcaca
    10741 caataataac cgtatatttg tagcatggct gtctgcctcc tcttaaattc agataaagag
    10801 gaggtagaca aatgcttgct atgagaaaca cataaatggt tataaccaag tgatgaaaca
    10861 attaattgca tgttgcggac tggattgcga aaattgcgcc gcccgtatag ccactgtcaa
    10921 taatgacgat gagctgagag agaaaaccgc caaagagtgg agtgtgctga acaatacgcc
    10981 ggaaattacg gcggaaacca tccattgtat ggggtgccgt gcagacgggg tgaagtttac
    11041 ctattgcagc gattattgtg ctatccgcaa atgtgtgtac gaaaaaggtt tcaatacttg
    11101 tggcgactgt aaggaactgg atacttgcca ggtggtaggt gcggttcttc agcatgcgcc
    11161 cggtgcaagg gaaaatcttt attaaccgta aaatctttga ttaaataaaa tattgcttat
    11221 ctttgcagta tgacaaagac atttaaatcg gatttggttt tgtaaacaat ctgtgttcca
    11281 tgcacagatt gtcccctttc gtttactttc ggataacttc tttcgagagt gtttttctat
    11341 tgttataatt caagtttaat ccgcatatta tgctgaaggt gttgtgatac tttccgtata
    11401 tgcaaaatat agtaagaaaa tgagtaacga aaataaaact atccacgatt tcgaatttaa
    11461 tttaatctgt gactttttct ccaatatgga acggcaaggc cctggcagtc ctgaagtgac
    11521 gttgaaggca ttgagctttg tagacggtct taccgatgaa tcccttattg ccgatatcgg
    11581 ttgtggaacg ggtggtcaga caatggtatt ggctggccat gttccgggac agattaccgg
    11641 aattgacctt ttccccggct ttattgacat cttcaaccgt aatgcaaggc agttgggctt
    11701 gcaggacaga gtaaaaggaa ttgtcggttc aatggatgcc ctccctttcg gtgaggagga
    11761 gctggatatg atttggtgtg aaggtgctat ctataacatc ggctttgaac gtggcttgaa
    11821 ggagtggcgt aaatatctga aaccgggagg gtatattgcc gtatccgaga gttcatggtt
    11881 tacggacgaa cgtcctgcgg aaatcaatga cttctggatg gacgcctatt ctgaaatgga
    11941 tacacttccc aatcaggtga ccaagttgta caaggcaggt tatcttcccg ttgctacatt
    12001 cattttgccg gagaattgct ggacagagca ttactttgct tcaaaggttg cggctcagga
    12061 gattttccgt aagaaatatg ccggtaataa aattgccgaa gagttcagct tactccaaat
    12121 gattgaggat gaactgtacg gcaagtataa ggaattttac ggttatgtgt tctttattgc
    12181 caagaaggta ggctgatgac ggacttctct tattgaggaa tgcgggtatt ctcaggacag
    12241 aatatccgca ttttgggttt tgagtagatt ttattgtttt gaggatgtac ggaacttctg
    12301 aggaggtatt cccgtatgac gtttaaagaa tttgttgaag aaggccgcat tattaaaacc
    12361 tagactcacg gctatatcct ttatcggagt gttggcggta caaagttgtg ctttggcatc
    12421 catgatgata gtattgttga tgatttccat ggctgtatat cctgattcct ttttgacaag
    12481 gcggcaaaga gctgccggtc tcatattcat tttcaatgca taataggaca cttgatgctc
    12541 ccggacatag tctgtgtgta ccaatcggat aaaaatgcgg tattggttga aatgcctgct
    12601 gcccggagtc tcttttattc tagggcgttc cggacagagt tcggatatac cttgtaacag
    12661 ataggtcagt agagtttgca atgaaactag acttgagggg ctttctgttc tttggtagag
    12721 gtgtgacaaa taggtcatga actcggcata aagctggaag tccgttctcg atagaggaaa
    12781 aatatagtgt ttgcctataa tgtgaaactt atccatcatg accttgccgg cccctgaact
    12841 ctggataagt tgttgggaaa atatgacgac atatatttca gcatcgtctg acgtgtgtag
    12901 caattgtacg aaggtctcgg gaggaataac taggagggcg ttagcttcaa ccctgaattg
    12961 agtatggttt atgatagttt tcagaactcc tttggtgcat agagcgaaga tactggcctt
    13021 ggtgtggtat ggcttttcca ctagcggatt cagttcattg gttgtgatat gattgcaggc
    13081 aatgaactcg tcatttatat tgaattcgga tatattcatg ttggagattt taagacgcaa
    13141 aaatggggga taataatgta taaatgacag aggtaacagt taaaatcaat attacgctca
    13201 acttatctct gttaaataag gtaaagttgt gaataataga atataagtaa ctaatcaaaa
    13261 ttaagcagca taatggctaa agttaatatt cagtcg
//
