LOCUS       c00046_gnlPro..        15938 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FKIBLBHE_46.
ACCESSION   c00046_gnlPro..
VERSION     c00046_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 08:49:49
            Original ID  :: gnl|Prokka|FKIBLBHE_46
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15938
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..168)
                     /locus_tag="ctg46_1"
                     /transl_table=11
                     /translation="MDFRPRNAHIRFFFASSRGRSCFNHFRDVYLHLLNRFISFHNLQC
                     QQHRTIRTGLG"
     protocluster    1..15938
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2467:5938]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2468..5938
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..15938
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15938
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(361..786)
                     /locus_tag="ctg46_2"
                     /transl_table=11
                     /translation="LGSYIRYRISNGRIYSTSSRLIVRQGPGTRIPVSKELQVIRHWPI
                     ICFPSQTPVGSTISYLNSCHEFLHRIKSRNRGHCCCSRIISIHSEPYLLQFRQISHCGS
                     RSVTHYCSQFNLRLLSGILYLLTFRATHYCCCSQSQK"
     CDS             complement(988..1365)
                     /locus_tag="ctg46_3"
                     /transl_table=11
                     /translation="MNKIEVIQFFIADSAVLFFHVRIISRTPWTNFRYKGYFCRLIGQR
                     QRITYLFAFTPGLCIIQVNGGSYSIKKNVFLIDVIDNIDFGIRIQRLGHQHPGCIHFHT
                     RCIHFQCTIVNRMCISGCSFL"
     CDS             complement(1421..2122)
                     /locus_tag="ctg46_4"
                     /transl_table=11
                     /translation="MKNRIEYTPESSYCISSQLGKFLYRLDFGMILQDKVVEGISILGK
                     RMYQHGKLIVGVVISKNESKFFPFETKHFPANLLLGQIGLGTFQKELQLGSNGQRIEYQ
                     WRGNLFHNMVIPVLTEEFRLTEPVTNAFHIRHGKYFVLGTNSLKDELTCMQHSSRILLT
                     VDKHFSFQQENYNIFLTLSRRQMESSEVGSIYYCIVHSLGTLSALFFTSASRRVGHRQV
                     DLFVCCSDKNR"
     CDS             complement(2468..3223)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_5"
                     /sec_met_domain="Fer4_7 (E-value: 2.8e-12, bitscore: 38.3,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 9.1e-26, bitscore: 81.2,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.1e-06, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQKGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISEGKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIPKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNVSISNIARLNRDFIIAKLKD"
     CDS             complement(3257..4042)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_6"
                     /sec_met_domain="FAD_binding_2 (E-value: 4.9e-14, bitscore:
                     43.2, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 3.9e-38,
                     bitscore: 121.5, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYEEITDVSPYENPMMIYPAIHYTMGGIWVDYELMTSIKGLFAIG
                     ECNFSDHGANRLGASALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEFAAAEKAV
                     QEKIDWMMNIKGKKSVDSIHKELGHIMWEYVGMGRTAEGLKEGLKKLKEVRKEFEKELF
                     IPGDKEGMNVELDKAIRLYDFITMGELVAYDALNRNESCGGHFREEYQTEEGEAKRDDE
                     NYFYVACWEYQGSDEKEPVLLKEPLVYEAIKVQTRNYKS"
     CDS             4064..5128
                     /locus_tag="ctg46_7"
                     /transl_table=11
                     /translation="LCNDIFTQTVDSFGEVKEYGKTGVVHAEALVAAFFGSAAGNVTRN
                     EVTECRITAFQVVVAVFLGNIFSLQCTFLQFLGIFQLLRNPDTTIVTQRFGHQSQLRLL
                     VTVNRDTSGVNLYVSRVGKPGTFTVASHCCRAVTCHCIGRKEVGIAVTTGSDYHSVGGK
                     TFQFTGNEVLCNDTAGTSVNEDNVFHFVAGIQFHSAYVHLAAQCRVCTQQQLLSGLTLG
                     IESTGYLSTTERTVVQCTAVFAGERNTLCNALVDNIVGYFSQTVNVGFAGTVVATLYCI
                     VEQTVYRVTVVLVILSSIDTTLCSDGVCTARRVLDAEVEYSETHFAQRGGSTGTGKSGS
                     YYDDVQTTFVGRVY"
     CDS             5132..5260
                     /locus_tag="ctg46_8"
                     /transl_table=11
                     /translation="LVSLIIGPFLSHRSFRYFRIYLSHNAIYNLVIYNLNLASAAQ"
     CDS             complement(5240..5938)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg46_9"
                     /sec_met_domain="SucD_FumR (E-value: 2.2e-129, bitscore:
                     419.9, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVALVSANGYNMV
                     CEFLGANWYALVATVGLAALFIIHIIYAFWLTMQNRKARGSERYAVTEKPKTVEWASQN
                     MLVLGIIVIVGLGLHLVNFWAKMQLPELMHNMGMHADTLTLAYAANGVYHIQNTFSNPV
                     FVVLYLVWLGALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLCFALVVVV
                     FFAKSLCGAC"
     CDS             complement(6101..6862)
                     /locus_tag="ctg46_10"
                     /transl_table=11
                     /translation="MLKGELLVNSDEYPGTTLQSRQLILQAIGSKVELLALTEVEYIVY
                     WFTELPLICEERYKEILKRSEAPLTYTPLTAISMLEGLLKSLACYLNEQPYACSKYIEM
                     KCQELVYILTCYYPLHQISTFFYPISTYTESFQYFVMQNYDKVKNVEEFAHLGGYTTTT
                     FRRLFKNMYGVPVYEWILDKKREGILNDLQYTKQRISVISARYGFDSLSHFAHFCKDSF
                     GDTPRALRKRSANGEKISIICKEQGKDQEDE"
     CDS             complement(7253..7609)
                     /locus_tag="ctg46_11"
                     /transl_table=11
                     /translation="MHSLVHTGNSHGTSPQGRRSYHIPFRILYTERGGKGKSRRRMSGR
                     ERRTAFTAICMHSVGIFIIRTLTVHQILHSISHNKSPRHTCTYVDRIFQQTLIMFYPSS
                     NRHRHRNTDSNIGL"
     CDS             7708..7806
                     /locus_tag="ctg46_12"
                     /transl_table=11
                     /translation="MILGANYAELDKLNPHNPCLSLFQVGYWIIVL"
     CDS             complement(7785..9401)
                     /locus_tag="ctg46_13"
                     /transl_table=11
                     /translation="MKKLFTIIICICAVTAQAQKPNNNEALRKLQMAEFAITNLYVDKV
                     DEDKLVEEAIIKMLAQLDPHSTYNNAEEVKKMNEPLQGNFEGIGVQFQMIEDTLLVIQP
                     VSNGPSEKVGILAGDRIVAVNDSAIAGVKMSTEDIMSRLRGPKDSEVKLTIVRRGVDDQ
                     LYFTVKRDKIPILSLDASYMIQPKTGYIRINRFGATTAEEFAEALKSLQKKGMKDLILD
                     LQGNGGGYLNAAIDLANEFLKQKELIVYTEGRAARRSDFFAKGTGNFKNGRLIILVDEY
                     SASASEIVTGAIQDWDRGVVVGRRTFGKGLVQRPIDLPDGSMIRLTIARYYTPSGRCIQ
                     KPYDSTANLDGRLTGENSQDKYNQELIDRFNHGEMIHADSIHFADSLKAQTKRMGRTVY
                     GGGGIMPDFFVPIDTTQYTDYHRNLVAKGVVIKATTGYIEKHRKELQNKYKKFEAFNEK
                     FEIDDNFLAEIRTLADKEKIKFDEKQYNQSLPLIKTQLKALIARDLWDMNEYFQVMNST
                     NQSVQQALKVLNEGIYSTIIQ"
     CDS             complement(9426..9884)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg46_14"
                     /sec_met_domain="CTP_transf_like (E-value: 1.3e-18,
                     bitscore: 58.7, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRAIFPGTFDPFTIGHSSVVSRALTFIDEIVIGIGINENKNTYF
                     PLEKREQMIRDYYRNEPRIIVQSYDCLTIDFARQVDAGLIIRGIRTVKDFEYEETIADI
                     NRKLTGIETILLFTEPELTCVSSTIVRELLQYGKDISMFIPEGMEIKN"
     CDS             complement(9881..11674)
                     /locus_tag="ctg46_15"
                     /transl_table=11
                     /translation="MYIGRLGDGSQNDDGIYVLLKEVMDNSIDEFKMGAGKRIEVTIED
                     NLRVSVRDYGRGIPQGKLIEAVSKLNTGGKYDSKAFKKSVGLNGVGIKAVNALSNRFEV
                     RSYRDGKVRTAIFEKGTLLSDATEDSTEENGTYIFFEPDNTLFYNYSFQNQFVETLLRN
                     YTYLNTGLTFIYNGQRIVSRHGLEDLLKDNMTSEGLYDIIHLKGEDIEIAFTHTSQYGE
                     EYYSFVNGQHTTQGGTHQTALKEHIARTIKEFYNKNQEYADIRNGLVAAIAIDVEEPMF
                     ESQTKTKLGSNNMWPAVPQEGKPAGPTVNKYVGDFIKTEVDNYLHKNPLVSEVMLQKIQ
                     DSEKERKAIAGVTKLARERAKKANLHNRKLRDCRYHLSDGKGKDQEAESCIFITEGDSA
                     SGSITKSRDVNTQAVFSLRGKPLNSYGLTKKVVYENEEFNLLQAALNIEDGIETLRYNK
                     VIVATDADVDGMHIRLLIITFFLQFFPDLIKKGHVYILQTPLFRVRNKKKTSYCYTEEE
                     RVKAIDELGPNPEITRFKGLGEISPDEFRHFIGKDMRLEQVSLRKTDLVKELLEFYMGK
                     NTMERQNFIINNLVIEEDLAS"
     CDS             11990..12295
                     /locus_tag="ctg46_16"
                     /transl_table=11
                     /translation="MIWRRRLSYSKPFTELLLFFFACRRESLRIGFYQLLIGGGVVNVF
                     HIFGYQVFDIFLQIHSIGSCFYGKIFEYILGYINHFSFLGHYCGFHISSFCFFANI"
     CDS             complement(12375..13397)
                     /locus_tag="ctg46_17"
                     /transl_table=11
                     /translation="MLNTFNKKKNAAFEFCEADYFLAYREGKIVGRVAAIINHKANQTW
                     NKKEVRFGWIDFIDDAEVSDALIRTVEEWGKERGMTYIQGPLGFTDFDAEGMLIEGFDQ
                     LGTMATIYNYPYYPQHLERMGFEKDADWVEYKIYIPDAIPDKHKRISDLIRRKYNLKVK
                     KYTSAKKIAQDYGQAIFELMNEAYQPLYGYSALSQRQIDQYVKMYLPILDLRMVTLITD
                     ADDQLLAVGISMPSLAEALQKAHGRLLPMGWYHLAKTIFLKKYPKMLDLLLVAVKPEYQ
                     NKGVNALLFSDLIPVYQQLGFEYAESNPELELNGKVQAQWEYFRTEQHKRRRCFVKEIG
                     "
     CDS             complement(13348..13605)
                     /locus_tag="ctg46_18"
                     /transl_table=11
                     /translation="MQPLTQGIKNKQAYFVLLSVCITFANPILNNYGNYNQESYHTTGT
                     GALYPLQLPAIQKQPLFRPRPFRRHAQYLQQEEKRCIRIL"
     CDS             complement(13593..14573)
                     /locus_tag="ctg46_19"
                     /transl_table=11
                     /translation="MDILLLVGGLLLILLGANGLTDGAASVAKRFRIPSIVIGLTIVAF
                     GTSAPELTVSISSALKGSADIAIGNVVGSNIFNTLMIVGCTALFAPIVITRNTLKREIP
                     LCILSSVALLICANDVFLDGSEENMLGIADGLLLLCFFAIFLSYTFAIAKRDGDTTNPE
                     KEPLQEEDEIRLLPVWKSALYILGGLAGLIIGGNFFVDGAGGIARGLGVSESVIGLTLV
                     AGGTSLPELATSIVAALKKNPEIAIGNAIGSNLFNIFFVLGCSASITPMRLTGITNLDL
                     WVLVGAGILLWLFGLFFGKRTITRIEGSILMLCYAAYMAVLICNL"
     CDS             complement(14513..14692)
                     /locus_tag="ctg46_20"
                     /transl_table=11
                     /translation="MLQTYGMFLTSYPNRHNFSLQTWQFCIQFALSLHPKSTHLWIYCF
                     LSEDCSSFFWAPMG"
     CDS             14913..15347
                     /locus_tag="ctg46_21"
                     /transl_table=11
                     /translation="LEAARLNEADLRMEMEQMKLAGYAADSVKLALQKQRIDSLRMVTP
                     GIPVVVEKDTLFYLYAKRGGHTPQQRAKDVSNVIEALGTRFNLRPDSVYLESTDIVTDL
                     MYGEKVIISFTDQDALWENCTRDQLAASKRHVVVDKLKAM"
ORIGIN
        1 accaagaccc gtgcggatag tcctatgttg ctgacactga agattgtgaa acgagataaa
       61 acggttcaag aggtgaaggt agacatcacg gaagtgattg aaacagctcc tccctcggga
      121 ggaggcgaag aagaacctga tgtgggcgtt cctgggtcgg aaatccatat cgaggttccc
      181 gtaccggagg acaaggttgt ggtggatgat ttggaaccgg gaaccgatga aggagatgga
      241 gggattggtg gcgatgtgga cgattgggat gatgagacgg atgtggagct accggtgaat
      301 tgatagcaaa cagacaaata aatatattaa ctttaataac agacaattat gaagaaggtt
      361 ttatttttgg ctttggctgc agcagcagta atgagttgct cggaaagtga ggagatagag
      421 aatgccggac aaaaggcgga gattaaattg ggaacagtag tgggtaacac tacgagagcc
      481 acagtgactg atttgccgga attgcagaag gtagggttca ctgtgtatgc ttataatacg
      541 ggagcaacaa caatggcctc tgttgcgact tttgatgcga tgaaggaatt catggcagct
      601 gttaaggtaa cttatagtgc tcccgactgg agtttgactg gggaaacata ttattggcca
      661 atgacggata acttgcagtt ctttgcttac gggaatccgg gtaccggggc cttgacgtac
      721 aatcaaccgg ctgctagtgc tatatatcct tccattactt atacggtagc ggatgtagct
      781 gcccaaacgg acttggtagc cgcgaaagcg acggatgcaa ccaaggcatc aaatgccagt
      841 ggggtatctt tgaaattcgg ccatatactg acccaaataa atttcactgt caaggcagcc
      901 gacgctttga cttataaact gaaaacactt acaatatccg gtgtgcacaa taaaggaact
      961 tatggttttg atgattcaat atggaagtca caggaaggaa cagccactta tgcacatacg
     1021 attgacgatg gtgcattgga agtgaataca acgggtgtgg aagtgaatac agcctggatg
     1081 ttgatgcccc agacgttgga tacgaatgcc aaaatcaatg ttgtctatga catctatgag
     1141 aaagacgttc ttcttgatac tgtaacttcc gccattgact tgaatgatac acaagcctgg
     1201 ggtgaaggca aaaagatacg ttatacgctg acgctggcca ataaggcggc aaaagtaacc
     1261 tttgtacctg aagttggtcc atggagtacg gctgatgata cgaacgtgga aaaataaaac
     1321 ggcactgtcc gcaataaaaa actgaattac ttctatttta ttcattcccc gaaacttctt
     1381 tatgaaagtt ttcggggaat gtttctttta tgagtattat ttatctattt ttgtcactgc
     1441 aacaaacaaa caaatctact tgccgatgcc caactcttct gcttgcagag gtaaaaaaca
     1501 atgcgctcaa tgtcccaagg ctgtggacaa tgcaataata tatgcttccc acctcagagg
     1561 attccatctg ccggcgcgaa agtgtgagga aaatattata attttcctgc tgaaaggaga
     1621 agtgcttgtc aacagtaagg agtatgcggg aactgtgttg catgcaggtg agttcatcct
     1681 tcaagctatt ggttccaagt acgaaatact tgccatgacg gatgtggaat gcgtttgtta
     1741 ccggttcagt aagcctgaat tcttctgtga ggaccggtat aaccatatta tgaaagaggt
     1801 tacccctcca ttgatattct atcctttgac cattactccc gagttgcagc tctttctgga
     1861 aagttccaag gcctatttgt ccgaggagaa gatttgccgg gaaatgcttt gtttcaaacg
     1921 gaaagaactt gctttcattc ttggaaatta ctactccgac tatgagcttt ccatgctgat
     1981 acatcctctt gcccagtata ctaattcctt ccactacttt gtcttgcaga atcatgccaa
     2041 agtcaagacg gtagaggaac ttgcccagtt gggaggatat acagtagcta ctttccggcg
     2101 tatattcaat tctgtttttc atcaaccggt gtacgagtgg atgatggaac ggaggaagga
     2161 aagcgtggtt tatgaacttc gttatacgga tgcttctata tcagagattt gctataaata
     2221 tggctttgaa tcgctgcctc atttttccaa tttctgcaaa aagaatttcg gggcttctcc
     2281 ccgtagcttg cgtgccggca atttatctga agtaaacggc atgtcataaa aaaactcctc
     2341 cggcggtttc ccggcagagg agtctcttgt gatattaatc aaatatagtg aaagctgagt
     2401 gataaatctg agcttgctca aaaggtttat ccgaagcgca tcctatatta tttgcagaaa
     2461 gaccggatta gtctttcagt ttcgcaatga taaagtcgcg gttcaggcga gcaatgttgc
     2521 tgatggaaac attcttcggg cattcagctt cgcacgcacg agtgtttgta cagttaccga
     2581 aaccgagttc gtccatcttg ctcaacatag ccttggcacg gcgcaatgct tccggtttgc
     2641 cttggggcaa caggttcagc tggctcacct tggcagaaac gaacagcata gcagaaccgt
     2701 tcttacaagc agccacacaa gcaccacaac cgatacagct ggcagcatcc atagcctcgt
     2761 cagcgatggg cttcggaatc aggatagcgt tggcatcctg gggagcaccg gtacgtacgc
     2821 tgacgtagcc gcctgcctgc ataatcttgt cgtaggccgt acggtcgacc atcaagtcct
     2881 tgataaccgg gaaaccggca gagcgccacg gttcaacagt gatggtatcg ccgtcgttga
     2941 aacgacgcat ataaatctgg caagtcgtag cgccggttgc aggaccgtgg gggtgtccgt
     3001 tgatgtagag cgaacacata ccgcagatac cttcgcggca gtcgtggtcg aatacaaccg
     3061 gttctttacc ttcagaaatc agctgttcgt tcaagatatc cagcatttcg aggaatgaag
     3121 tatcgcccgg gatatctttc atttggtatg tttcaaaagc gccttttgct ttcggaccct
     3181 tctggcgcca taccttgagc gtaaatgata tatttttatc cattttcttt aattctttaa
     3241 atgttcaact tcccgattag cttttgtagt tacgagtctg taccttgatt gcttcgtaaa
     3301 ccagcggctc tttcagcaat accggttcct tttcgtcaga accctgatat tcccagcaag
     3361 ccacgtagaa gtagttttca tcgtcacgct tggcttcgcc ttcttcagtc tgatattctt
     3421 cacggaagtg accgccgcag ctttcgttac ggttcagtgc atcgtaagca accagctcgc
     3481 ccatagtgat gaagtcgtac agacggatag ccttgtcgag ttctacattc ataccttcct
     3541 tgtcgcccgg gatgaacagt tctttctcga actccttgcg gacttctttc agcttcttca
     3601 gaccttcctt caagccttcg gccgtacgtc ccatacctac atattcccac ataatgtggc
     3661 ccagttcctt gtggatagag tctacagact tcttaccctt gatgttcatc atccagtcaa
     3721 tcttctcctg aacggccttt tctgcagctg caaattcggg caggtcggta gagaaacggg
     3781 gaactgtaat ctggtcggcc agatagttct ggatagtgta aggcaatacg aagtaaccat
     3841 cggccagacc ttgcatcagg gcggaagcac cgaggcggtt tgcaccgtgg tcggagaagt
     3901 tacattcacc gatggcgaac agtcccttga tggaggtcat cagttcgtag tcaacccaga
     3961 taccacccat ggtatagtgg atagccggat aaatcatcat cgggttttcg tatgggctga
     4021 catcagtgat ttcttcatac atatcgaaga ggttgccgta acgttgtgca acgacatctt
     4081 tacccagacg gttgatagct tcggagaagt caaggaatac ggcaagaccg gtgttgttca
     4141 cgccgaagcc cttgtcgcag cgttctttgg cagcgcggct ggcaacgtca cgcggaacga
     4201 ggttaccgaa tgccggataa cggcgttcca ggtagtagtc gcggtcttcc tcgggaatat
     4261 cttttccttg cagtgtacct tcctgcagtt tcttggcatc ttccagcttc ttcggaaccc
     4321 agatacgacc atcgttacgc agagattcgg acatcaaagt cagcttagac tgcttgtcac
     4381 cgtgaaccgg gatacaagtg gggtgaatct gtacgtaagc agggttggca aaccaggcac
     4441 ctttacggta gcaagccatt gctgcagagc agttacatgc cattgcattg gtagaaagga
     4501 agtaggcatt gccgtaacca ccggtagcga ttaccacagc gtgggcggca aaacgttcca
     4561 atttaccggt aacgaggttc tttgcaatga taccgcgggc acgtccgtca atgaggacaa
     4621 cgtcttccat ttcgtagcgg gtatacagtt tcacagtgcc tacgttcacc tggcggctca
     4681 atgcagagta tgcacccagc aacagctgct gtccggtctg acccttggca tagaaagtac
     4741 gggatacctg agcaccaccg aaagaacggt tgtccagtgt accgccgtat tcgcgggcga
     4801 aaggaacacc ttgtgcaacg cattggtcga taatattgtt ggatacttca gccagacggt
     4861 aaacgttggc ttcgcgggca cggtagtcgc caccctttac tgtatcgtag aacagacggt
     4921 atacagagtc accgtcgttt tggtaattct tagcagcatt gataccacct tgtgcagcga
     4981 tggagtgtgc acggcgcgga gagtcctgga tgcagaagtt gaatactctg aaacccattt
     5041 cgcccagaga ggcggcagca ctggcaccgg caagtccggt tcctactacg atgatgtcca
     5101 gacgacgttt gttggcaggg tttactaatt tttggtgagc cttataattg gtccatttct
     5161 cagccaccgg tccttccggt attttagaat ctatcttagt cataatgcaa tttacaattt
     5221 agtcatttac aatttgaatt tagcaagcgc cgcacaatga ttttgcaaag aatacgacaa
     5281 ctaccagagc gaagcagagg acaacgatag tagaatagat gttggagata catttccaac
     5341 ggttaatcca tactttgttg ttccagccca aagactgcat ggagctccag aaaccgtgag
     5401 tgaggtggaa ccacaatgcg cccagccaaa cgaggtaaag cactacgaat accggattgc
     5461 tgaaggtgtt ctgaatgtga tagacaccgt tggctgcata tgccagcgtg agggtgtcag
     5521 catgcatgcc catgttgtgc atcaactcgg gaagctgcat tttagcccag aagtttacca
     5581 ggtgcaggcc caaacccacg attacgatga tacccagtac gagcatgttt tgagaagccc
     5641 attccacagt cttgggcttt tccgtaacgg catagcgttc gctaccacgt gccttacggt
     5701 tctgcatagt cagccagaaa gcgtagatga tgtggatgat gaataaggca gccagaccta
     5761 ccgtagccac caatgcgtac cagtttgctc ccaggaactc acaaaccatg ttgtagccat
     5821 tagccgagac taatgcaacc aggttcatcg ccatgtgaaa tgtcagaaac aggacaaggg
     5881 cgataccggt aacgctcatc accactttcc ttcctacaga tgaattactt aaccacataa
     5941 atgattgaat ttaagttatt taatagtttg aaaatttgtt ctatcaggat acttctgtaa
     6001 atgtttcgca aaaataggag aaatccagcg ataaagcaag cgattaaaga aataattccg
     6061 taatccggca gaatgcgaag tttacggaca agtaaaaggt ttactcgtcc tcctggtctt
     6121 tgccttgctc tttgcagata atggaaatct tttctccgtt tgccgagcgt tttctcaggg
     6181 cgcggggcgt gtctccgaaa gagtctttgc agaagtgggc aaagtgggat agggaatcaa
     6241 agccatagcg ggcgctgatg actgaaatgc gttgtttggt gtattgcagg tcgttcagaa
     6301 ttccttcacg tttcttgtcc agaatccatt catagaccgg gaccccatac atatttttaa
     6361 acagacggcg gaatgtggtg gtggtatatc caccgaggtg ggcaaactct tccacattct
     6421 tcaccttgtc gtagttctgc atgacgaaat attggaagct ttccgtataa gtgctgatgg
     6481 ggtagaagaa tgtactgatt tggtgtagcg gatagtagca tgtcaatatg tataccaatt
     6541 cctggcattt catttcaatg tatttgctgc acgcataggg ttgctcgttg aggtagcagg
     6601 caaggctttt caggagccct tcgagcatgg aaatcgcggt aagcggggta taagtcaagg
     6661 gggcttccga gcgtttcagt atctccttgt agcgctcttc gcaaatcaga ggaagctcgg
     6721 tgaaccaata gacaatatat tccacttcgg tcaaagccag gagttctact ttggagccga
     6781 tggcttgcaa gatgagctgg cggctttgga gagtggtgcc cggatattcg tcactgttta
     6841 caagtaattc acctttcagc ataaatatca tgcagttctg tgtgcacttt tcagcagaga
     6901 aatgttgtcc cttggggtag tggcggtaaa ccaatactcc ttctgatttt tggggacata
     6961 ccatacaatc aatctgtcgg ttgcagcaag tttccagtct catgaaatga ttagcgaatt
     7021 attataaatg tggcaacaaa gatagaattt ttttgtgaaa actctatcta tttgtcctat
     7081 ctttgcgtca aactaatata aaggacttat gaaaaaggct attttttttg tatattttat
     7141 ctgccttgtt gtatccggtc tttcagcaca gaattgggat atcaacactt tgcaccgggt
     7201 gaacagttgg gatggcaagt ttgtccgtaa ctataataag ataatttcac gttcagagcc
     7261 ctatgttgct gtcggtgttc cggtggcgat ggcggttgct gcttggataa aacatgataa
     7321 gggtttgctg aaagatgcgg tctacgtagg tacaagtgtg gcgggggctt ttgttgtgac
     7381 ttatggaatg aagtatctgg tggaccgtga gcgtccttat gataaatatc ccgacagagt
     7441 gcatgcatat agccgtgaaa gcagtccgtc tttcccttcc ggacatacgg cgacggcttt
     7501 tgcccttgcc acctcgctca gtgtaaagta tcctaaatgg tatgtgatag ctccgtctgc
     7561 cttgtgggct tgttccgtgg gagtttcccg tatgaacgag ggagtgcatt atccgtcgga
     7621 tgtgttggcg ggggctgcaa tcggtgctgg atgtgctgtg gtcaacatct acgtcaacaa
     7681 gtggctgaat aagtggctgt tcggagaatg attttaggcg cgaattacgc ggaattagat
     7741 aaactaaatc cgcataatcc gtgcctaagt ttgtttcaag tcggctattg gataatagtg
     7801 ctgtagatgc cttcgttcag cacttttaga gcttgctgca cgctctggtt cgtactgttc
     7861 atcacctgga agtattcgtt catgtcccat aggtcacggg ctatcaaggc tttaagttgt
     7921 gtcttgatga gcggtaggga ttggttgtac tgtttctcgt caaacttgat tttctctttg
     7981 tcggcaagcg tacgtatttc ggcaaggaag ttatcgtcta tctcgaactt ctcgttgaag
     8041 gcttcgaatt tcttgtattt gttctgcaac tccttccggt gcttctcgat gtagccggta
     8101 gtggctttga taaccacgcc tttggctacg aggttgcggt gatagtctgt gtactgggta
     8161 gtgtcgatgg ggacgaagaa gtcgggcatg atacctccac ctccgtaaac ggtacgtccc
     8221 atacgcttgg tctgtgcttt cagggagtcg gcaaaatgga tactgtccgc atgaatcatt
     8281 tctccatgat tgaagcggtc tatcagttcc tggttatact tatcctgact gttctcgccg
     8341 gttaggcggc cgtcgaggtt ggcggtgctg tcgtaaggct tctggataca acggcccgaa
     8401 ggagtatagt agcgggcgat agtgaggcga atcatggaac cgtccggcag gtcgatagga
     8461 cgctgtacca atcccttgcc gaaggtgcgg cgtcctacta ccacgcctct gtcccagtcc
     8521 tggatggctc cggtcacgat ttcactggca gaagcggagt actcgtccac caatatgatg
     8581 agacggccgt tcttgaagtt gcccgtacct ttggcaaaga aatcactgcg gcgtgcggcc
     8641 cttccttcgg tgtagacgat gagttctttt tgcttcagaa attcgttggc aaggtcgatg
     8701 gcggcattca gataccctcc tccatttcct tgcaggtcga ggatgaggtc tttcattcct
     8761 ttcttttgca ggcttttcag ggcttctgca aactcttcgg cggtggttgc cccgaagcgg
     8821 ttgatacgga tatagccggt tttgggttgt atcatgtaag atgcgtccag gctgaggatg
     8881 ggaattttgt cacgcttcac ggtgaagtac agctggtcgt ccacgccacg gcgcacaatg
     8941 gtgagtttca cttccgagtc tttcggtccg cgcaggcggc tcataatatc ttccgtgctc
     9001 atttttactc cggcaatggc gctgtcattg acggctacga tacggtcgcc ggcaaggatg
     9061 cccaccttct cggaaggtcc gttgctcacg ggttgtatca caagcagggt atcttctatc
     9121 atctgaaact gtacgccgat gccctcgaaa ttgccttgca acggttcgtt catctttttc
     9181 acttcttcgg cattgttgta ggtggagtgc gggtcgagct gcgccagcat cttgatgatg
     9241 gcttcttcca ccagcttgtc ttcatccacc ttgtccacat aaaggttggt gatggcaaac
     9301 tctgccattt gcagtttgcg cagggcttca ttattattcg gcttttgcgc ttgcgccgtc
     9361 actgcgcata tacatattat aattgtaaat agtttcttca tcatttccat tttggttctt
     9421 aatccctaat tcttgatttc cattccttcg ggtatgaaca tgctgatgtc ctttccgtat
     9481 tgcagcagtt cgcgcacgat ggtggagctg acgcaggtaa gttccggctc ggtgaagagc
     9541 aggatggttt ctatgccggt cagcttgcgg ttgatgtcgg caatggtttc ctcgtattca
     9601 aaatccttca cggtgcgtat gccgcgtatg atcaggccgg cgtctacctg ccgggcaaag
     9661 tcgatggtca ggcaatcgta tgactgcacg atgatgcgcg gctcgttccg gtagtagtcc
     9721 cgtatcatct gctcgcgctt ttccaggggg aaatacgtgt tcttgttttc gttgatgcct
     9781 atgcctatga cgatttcgtc gatgaaggtc agcgcacggc tcactaccga agagtgtccg
     9841 atagtaaacg ggtcgaatgt tcccggaaag atagctcttc tcatgatgcc aaatcttctt
     9901 ctataaccaa gttgttgata ataaagtttt gccgctccat ggtattcttg cccatgtaga
     9961 actccagcag ctcttttacg aggtcggtct tgcgcagcga cacttgctcc agacgcatgt
    10021 ccttgccgat gaagtggcgg aactcgtcgg gcgagatttc tcccagacct ttgaaccgtg
    10081 tgatttcggg attgggaccc agctcgtcaa tggctttcac acgttcctcc tcggtgtagc
    10141 aatagcttgt cttcttcttg ttgcgcacgc ggaagagcgg ggtttgcagg atgtatacgt
    10201 gtcccttctt tatcaggtcg gggaagaact gcaggaagaa tgtgataatc agcaggcgga
    10261 tgtgcatgcc gtccacatcg gcatcggtgg ctacgatgac tttattgtag cgcagcgtct
    10321 ctatgccgtc ttctatattc aaggccgcct ggagcaggtt gaattcttcg ttttcataaa
    10381 ccactttctt ggtaagtccg taggagttta gcggcttgcc gcgcaggctg aataccgcct
    10441 gtgtattcac gtcgcggctc ttggtgatgg agccgctggc cgagtctccc tcggtgatga
    10501 agatacacga ttcggcctcc tggtccttgc ctttgccgtc actcaggtgg tagcggcagt
    10561 cgcgcagctt gcggttgtgc aggttggctt tcttggcacg ttcacgtgcc agcttggtga
    10621 caccggcaat ggctttgcgc tctttctcgg agtcttgtat cttttgcagc atcacttcgg
    10681 agacgagcgg gttcttgtga aggtagttgt ccacttccgt cttgatgaag tctcccacgt
    10741 atttgtttac tgtggggccg gcgggtttgc cttcctgcgg cacggcgggc cacatgttgt
    10801 tgcttcccag tttcgttttg gtctggctct cgaacatggg ttcctccacg tcgatggcga
    10861 tggcggctac caggccgttg cgtatgtcgg catactcctg gttcttgttg tagaactcct
    10921 tgatggtacg ggcaatgtgc tctttcaggg cagtctggtg tgtaccgcct tgggtggtgt
    10981 gctgtccgtt gacaaaggag tagtactctt cgccgtattg gctggtgtgc gtgaaggcta
    11041 tctcgatgtc ttctcctttc aggtgtatga tgtcgtaaag gccttcgctg gtcatgttgt
    11101 ctttcagcaa gtcctccagt ccgtggcggg aaacgatgcg ctgtccgttg taaataaagg
    11161 taagccccgt attcaggtag gtgtagttgc gcagcagcgt ttctacaaac tggttctgga
    11221 aggaatagtt gtagaagagc gtgttgtccg gctcaaagaa gatataagtt ccgttttctt
    11281 ccgtcgaatc ctcggttgcg tcgctcaaca gcgttccttt ttcaaagatg gcggtgcgta
    11341 ccttgccgtc gcggtagctg cgtacctcga aacggttgct cagcgcattg accgccttga
    11401 tacccacacc gttcagcccg acgcttttct tgaaagcctt gctgtcgtac tttcctccgg
    11461 tgttcagctt gctgaccgcc tctatcagct tgccttgcgg aatgcctcgg ccgtagtcgc
    11521 gcacgctgac gcgcaggttg tcttctatag tcacttctat gcgttttccg gcacccatct
    11581 tgaactcgtc gatgctgttg tccatcactt ctttcagcaa cacatagatg ccgtcatcgt
    11641 tctgggagcc gtcgcccagg cgaccgatgt acatgcctga acggacacgg atatgctcca
    11701 tgtcgtccag gtggcggata ttgtcgtcgg tatatgatac tgttggttcg ctgaattgca
    11761 gactaccatt gatattcagt tcttcttcca tggaattttg attgttaggg atacttggtc
    11821 atttgtcttt ctgccttaag ttcttttccg ttttcttggt atatgcctcg cctttgggca
    11881 aaagatattc aaatagaacg gtgtcatcta ctatttggac atgaaatata aagaacgccc
    11941 gataactgcc tatgcggata tggtaacagc ttttcggctg attttataaa tgatttggag
    12001 aaggaggctt tcatattcca agccatttac ggaactgctc ctgttcttct tcgcttgccg
    12061 gagagagtcc ctccggattg gtttttatca attgctgata ggtggcggag tcgtcaatgt
    12121 cttccacatc tttggctatc aggttttcga tatatttctt cagattcatt ccattggcag
    12181 ctgcttttat ggaaagatat ttgaatacat tctcgggtat atcaatcact tttcttttct
    12241 tgggcattat tgtggcttcc atatctcttc tttttgtttc ttcgcaaata tataatttat
    12301 atatgatata tacaaaagga aggtcttgtg tttattgaaa gttcacatac tccaaaggac
    12361 tatgccatct gcggttatcc tatctccttc acaaagcatc ttctcctctt gtgctgttcc
    12421 gtcctgaagt actcccattg cgcctgtacc ttgccgttca gctccagctc cgggttgctt
    12481 tcggcatact cgaatccaag ttgctgatag acggggataa ggtcggagaa cagcagtgca
    12541 ttgacgccct tgttctggta ctccggtttt acggcaacca gcagcaggtc gagcattttg
    12601 ggatatttct tcaagaagat ggtcttggcc aggtgatacc aacccatagg aagcaggcgc
    12661 ccgtgggctt tttgcaacgc ttcggcgagt gacggcatgg aaatgcctac ggcaagcagc
    12721 tggtcatcgg catcggtaat caatgtcacc atgcgtaggt cgaggatggg caggtacatc
    12781 ttgacgtatt ggtcaatctg ccgttggctc agtgcagaat agccatagag tggctgatag
    12841 gcttcgttca tcagttcgaa gatggcctga ccgtagtctt gggcaatctt cttggcagat
    12901 gtgtatttct ttaccttgag gttatacttg cgccggatga ggtcggagat gcgcttgtgc
    12961 ttgtcgggta tggcgtcggg aatgtagatt ttgtactcca cccaatcggc atccttctca
    13021 aagcccatgc gttccaggtg ctgcgggtag tagggatagt tataaatggt ggccatggtg
    13081 cccagttggt cgaatccctc gataagcatg ccttcggcat cgaagtcggt gaatcccagc
    13141 gggccttgta tatacgtcat tccccgttct tttccccatt cttccacggt gcgtatcagg
    13201 gcatcggata cttccgcatc gtcgatgaag tctatccacc cgaagcgtac ttccttcttg
    13261 ttccaggttt ggtttgcctt gtggttgatg atggcagcta cacgtcctac gattttacct
    13321 tcccgatagg ccagaaaata gtcggcttca cagaattcga atgcagcgtt tttcttcttg
    13381 ttgaaggtat tgagcatgtc gtcgaaaagg tcggggacgg aataagggtt gtttttgtat
    13441 agcaggtagt tgaagcggat aaagcgctcc agttcccgtc gtgtggtaac tttcttgatt
    13501 gtaattgcca taattgttca atattgggtt cgcaaaggta atgcaaactg agagcagaac
    13561 aaaataagct tgcttatttt ttatgccctg tgtcagaggt tgcatatcag tacagccatg
    13621 taggccgcgt agcagagcat cagaatgctt ccttcgattc gggtaatggt gcgtttcccg
    13681 aagaacaagc cgaacagcca gagcaggatg cccgccccca cgagtaccca caaatcgaga
    13741 ttggtgatgc ccgtcagacg cattggggtg atggaagccg aacagcccag cacgaagaat
    13801 atgttgaaga gattgcttcc gatggcgttc ccgatggcta tttcggggtt tttcttcagg
    13861 gcggctacga tggaggtggc aagttcgggc agtgatgtgc cgcctgccac gagcgtaagg
    13921 cctatgacgg attcgctgac gcccaatccg cgggctatgc cgccggcgcc gtctacaaag
    13981 aaattgcccc cgatgatgag tccggcaagt ccgccgagaa tgtatagggc agacttccac
    14041 accggcagca gcctgatttc atcctcttcc tgcaggggct ccttttcggg gttcgtcgtg
    14101 tctccgtccc tttttgcgat ggcaaaggtg taactcaaga aaatggcaaa gaagcacagc
    14161 agcagcagtc cgtcggcaat gccgagcatg ttttcctcac tgccgtccag aaagacgtcg
    14221 ttggcgcaaa tcagcagggc gacggacgaa agtatacaaa gggggatttc gcgtttcagc
    14281 gtattacggg tgatgactat cggagcgaaa agggccgtac agcccacaat catcaaggta
    14341 ttgaatatgt tgcttcccac cacattgccg atggcgatgt ctgcgctgcc tttcagggcg
    14401 gaggatatgc tgacggtgag ttccggtgcg gaagtgccga aggcgacaat ggtaagcccg
    14461 atgacgatgg acggtatgcg gaaacgtttg gcaacggatg cggcgccgtc tgtcagccca
    14521 ttggcgccca gaagaatgag gagcagtcct ccgacaagaa gcaatatatc cataggtgtg
    14581 ttgattttgg gtgcaaagat agtgcaaact gaatgcagaa ctgccatgtt tgcaaagaaa
    14641 agttatgtcg attagggtag gaagttaaaa acattccgta tgtttgaagc atttattgag
    14701 tatgtttgca taattaaaga atcaaataaa gaagtttata tatgaaagta atccgtgctt
    14761 tctgtctctg ttggctgttg atgctggcag gaggagtgtc agctcagctg gtagataaag
    14821 tgctcagtgt tttggatgaa gacagtgtga atactgttac agtagtaaag gccgactccg
    14881 attcgattca attgtcgctc atcaggcagt aattggaagc agcccggctg aacgaagcgg
    14941 atctgcggat ggaaatggaa cagatgaagc tggcgggcta tgcggccgat tcggtgaagt
    15001 tggcattgca gaaacaacgc attgattcgt tgcggatggt gacgcctggt attccggtgg
    15061 tggtggagaa ggacactttg ttctatctgt atgccaagcg tggagggcat acgcctcaac
    15121 agcgggccaa agatgtaagc aacgtcatcg aagcattggg cacgcgtttc aatctgcgtc
    15181 cggactctgt ttatttagag agtacggata ttgttacaga cttgatgtat ggcgaaaagg
    15241 tcatcatttc ctttaccgat caggatgctt tgtgggaaaa ctgtacccgc gaccagctgg
    15301 ccgccagcaa gaggcatgtc gtggtggaca aactgaaagc catgtagaag gagcatagct
    15361 tgtggcagtt gggtaagcgt atcttgtact tcggcttgat tgtttcgctc ggttccagta
    15421 cggttatcgg caatatcatt gcaggactgg tcataaccta catgcggcct ttcaagctgg
    15481 gtgaccgcat caagctgaac gatactacgg gcaacatcat tgagaaaaca ctgctcgtca
    15541 cccgcatccg tactccgaag aatgaggtgg tgaccattcc gaactctttc atcatgtctt
    15601 cccatacggt caattacagc cagtctgccc gtgagtatgg attgattatc cattcggagg
    15661 tcagtattgg ctacgatgtt ccgtggcgga agacacatca gctgttgata gaggctgcat
    15721 tgaatactcc tggagtgata gatgatcccc gtccgtttgt attggagact tcccttcagg
    15781 attattatcc ggtttatcaa gtgaatgcct atatcaggga tgccaacagc cttagccaga
    15841 tttattctga tttgcatcac aatatccagg atgtctttga cgaggcaggc atcgaaatca
    15901 tgtctcctca ctatatagct acgcgtgacg gcagtgag
//
