LOCUS       c00008_gnlPro..        16755 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JHMCPDBA_8.
ACCESSION   c00008_gnlPro..
VERSION     c00008_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 11:07:32
            Original ID  :: gnl|Prokka|JHMCPDBA_8
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16755
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16755
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2276:6755]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2277..6755
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
     cand_cluster    1..16755
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /kind="single"
                     /product="Glycine_cleavage"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16755
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Glycine_cleavage"
                     /region_number="1"
                     /rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T, GDC-P,
                     SoxG]) and GCV_H and GCV_T_C)"
                     /tool="gutsmash"
     CDS             98..1021
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S11"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_1"
                     /sec_met_domain="Peptidase_S11 (E-value: 2.2e-54, bitscore:
                     177.6, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLFALLAGFSLCLSSTSCQSYGDSSDYIPLATPVPPQLSQPVSH
                     ALPRPANFPTRPVAIPSSAPRTPRCASACVMDALTGNVLFSHNGLQRRQVASTQKLVTA
                     MVVMGHGSLDKKVVIQPSDTKADPTKLGFRAGEVYSRRELLNAMMIRSFNDVALALARD
                     TAGSVPRFAQLMNAKARQMGMYNSRFANPNGLPADQYSTAIDMARCAYYVYRNPELRNI
                     ICKRQYAFTRANGRTLLLRNTNKLLTQNPWVTGMKTGYTNAAGRCLVSSAGVNGRHVIV
                     VVLGCHPSRIWTESENLIRWALGTAA"
     CDS             1080..2201
                     /locus_tag="ctg8_2"
                     /transl_table=11
                     /translation="MLQAGIVGLPNVGKSTLFNAVTRTRKAQAANYPFCTIDPNVGMVT
                     VPDPRLQVLSDMSGSEKIIPTLIEFVDIAGLVKGASEGAGLGNQFLANIREVDAIVQVV
                     RCFDNDDIIHELGSVDPLRDIDIINSELILADIATMEKRLSSRERKARSGDKEAKAEVA
                     LITKLLPHLNEGNPALTLEPQLDDDERKLLHSFQLLSDKKSIFACNVNEDELADAISNP
                     DAHPYVSQVKKYVAEHHNAEAIVISARIEEELIDVSEEESREFLESLGVKDSGVSDLIR
                     AVYHLLGLRTYLTTGIKETRAWTIPSGAKAPQAAGVIHTDFERGFIAAEVVHYDDLVSC
                     GGKAGAREHGKLRIEGKEYVVKDGDVIEFRFNV"
     CDS             2277..3362
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_3"
                     /sec_met_domain="GCV_T (E-value: 4.7e-87, bitscore: 284.7,
                     seeds: 72, tool: rule-based-clusters)"
                     /sec_met_domain="GCV_T_C (E-value: 4.5e-23, bitscore: 74.2,
                     seeds: 348, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTDVKSTPLAAKHVELGARMVPFAGWNMPVQYTGILDEHKAVR
                     ETCGIFDISHMGQFTVAGGSAAAWLNSMLTNDINKLNVGQGQYSVMLNDRAGVIDDLIL
                     YRMEPETFFVVVNASKIDEDFAWLSAHQPAGVTLENHSDEYVGLAVQGPECGKVFSRVI
                     PGVELPPRNGISRITAEGTDLIICRTGYTGEDGFEFFCPAKEGVKWFEAFLGAGAKPCG
                     LGARDSLRLEMCYPLNGSDLSPDKTPLEAGLGFFCALDTDFIGSDILREQKANGLSRRL
                     AAIEYTGKGAPPRAHYAVHVPGGEAIGELTSGVLSPSLMKGIALAYLPAAHAKVGTELE
                     IDVRGRKFPAVVVKKPFYKKG"
     CDS             3433..3813
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_H"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_4"
                     /sec_met_domain="GCV_H (E-value: 2.4e-47, bitscore: 153.0,
                     seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDVPENLLYSKDHEWIEIDGDIGTIGISDHAQAELSDVVFVDLP
                     EVGATVAAGDPVAVVESVKAASDVYTPVSGEILEVNEELSNDPSLINSDPYGAGWLYKI
                     RLDVPTETEDMMNATDYEEYCS"
     CDS             3909..6755
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GDC-P"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Beta_elim_lyase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_5"
                     /sec_met_domain="Beta_elim_lyase (E-value: 1.6e-09,
                     bitscore: 30.6, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="GDC-P (E-value: 1.1e-177, bitscore: 584.3,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTHSDFASRHIGPQGEERREMLDSLGYRTLDELIADIVPADIRM
                     KAPLDLPAAKSETEALKELRSILRKNKLLKTFIGQGYYGTITPSVILRNVLENPGWYTA
                     YTPYQPEIAQGRLEMLMNFQTMVSSLTGLPVANASLLDEGTAAAEAVTMCRNARPKANT
                     FFVADTCHPQTISVIRTRAAFQGVNIIVGDCSSFDPASIGADLAGVLVQYPDTLGCICD
                     YTDFFSRVHATGALCVVAADLMALTVIREPGAFGADICIGNTQRFGVPMGFGGPHAAYM
                     SCTDALKRRMPGRLIGMSIDTLGRPAYRLALQTREQHIRRDKATSNICTAQVLLAVLAA
                     FYTVYHGQEGLKRIGTEIHLKTKSLYKALTEAGIAIENKNFFDTLLLSVPGQADAMVQK
                     ALEAGYNIRRVDADHAAISLDETATCADIAALASALAGAETSATCDCDAPAWDPVHTRQ
                     TPFCTEKAFNSYHSETEMMRYIRRLESRDLALNEAMIPLGSCTMKLNAASEMIPITWPE
                     ANSLHPFVPADQSEGIREMLSVLSDRLAKITGFAAVSLQPNAGAAGEYAGLLAIRRYQK
                     HAGEGHRNVCLIPTSAHGTNPASSAMAGLKVVPVKCDERGNINMADLKSQAEAHKDNLS
                     CIMVTYPSTHGVYEQTIKELCDIVHANGGQVYMDGANMNAQVGLTCPGCIGADVCHLNL
                     HKTFAMPHGGGGPGIGPIGVAEHLVPFLPGHLTLGHEEGAVASAAWGSASIAAICWMYL
                     SMMGPDGLREATEMAILNANYIAKKLGHLFPVLYSGNKGLVAHECILDPRQLTHDAGLT
                     VDDIAKRLMDYGFHGPTMSFPVPGTLMVEPTESEPKKELDRFIEAMERIHAEITAIING
                     TADKEDNVLKNSPHTAEMVSADEWRHPYSRSEAAYPVSGLLIHKFWPYVGRVDNVYGDR
                     NLVCTCDTVEEFSKAVEL"
     CDS             6814..6987
                     /locus_tag="ctg8_6"
                     /transl_table=11
                     /translation="MFKNRISNPKSTLYFEYKWVIKMKGEEKQGRRNVPFSFLIHTAFM
                     LNCFLDAFVSSD"
     CDS             7110..8075
                     /locus_tag="ctg8_7"
                     /transl_table=11
                     /translation="MIFHHVFGLYALPAGVDTAWIAPQLTKAAPIFKICVPIFIFITGY
                     AMGWKTNSSPTFGSLIKTGFSHYFKFWKIYFLCLLLAILVSWAFPLPILPSVADMGWKN
                     GLLVVTGLRPCYPDWWYMALFAAATMALYPICAWITHHIAPVPSMAALLGVSLLFQSTA
                     HIPSLPGIAYSFPPFLPCFILGYMCAFLASRLSALSISQSLGAILLLALEILSIHLFSF
                     SKAKTLTVIFLFTLWCLPWITRKLRLTPLLTLLGTYSALMWLNHRFIFGYHFSWDLYGT
                     QSISVVFIVTLVSSLLLAMAMQKLFNRMIPSNPQTQSKTL"
     CDS             complement(8107..8739)
                     /locus_tag="ctg8_8"
                     /transl_table=11
                     /translation="MSDLYEYQAIDGSSKGPVDLVLLLRARNLGRLSNRTLVRKVPGGD
                     WRPLASFIPSMTVMDDDGEPSVLPDPGSEPGGTDSGWSRKKYWIRVIKAWCRFEGRAGK
                     GELHEVFSRVGVAWLAVAGVPSFAECGLFPSLVPWVELVSPLLYVVLAVLSIPLAATMV
                     RRLHDVGRSGFFLVFLAVPFIGWLLLWYLSHGESRIGENKYGDPPWN"
     CDS             complement(8748..10907)
                     /locus_tag="ctg8_9"
                     /transl_table=11
                     /translation="MKLVSLLSVLLTSLVPCMGASGQATKPAARSVKTSKPNVIFILVD
                     DMGWGDLDSNWSQQKLNGRTVERKNEFKTPALSALAREGIQLRRHYSAAPVCAPARASL
                     LLGVHQGNSRVVRNNRFDQPIEDSHTLGTVMRDAGYDTAAIGKWGVGGGGQSHVPMTAG
                     PHQRGFNYFYGILDHLAGHFHYPSESRDVFEYNGYASNPEWKNIKDQVPQTAYSTDLFA
                     ARAKQWIVDQRKSARKTGKPFFLYLAFPAPHGNLVVPGVPYPSGGGLKGGLQWVKKEGT
                     ESVNTAFDARAEKNKDTYIHPDNSRFPNDVAKRHSTMIRRVDDAVADLIRLLKDLKIDD
                     NTMIVFTSDNGPHNEGGSDPRHWHGAQNPQFFKSYGMMDGIKRDCWEGGMRVPTLVRWP
                     ARIPKGQISLHPGQFHDWLATLADVAGVPVPARSDGVSLLPTLTGHADQQKPGIVYAEY
                     NFAGKTPEYKDFLGEHKGAQRGQQQIVFVDGLKGLRMGVKDADKDFMIFDTLNDPQESK
                     DLASSKPELQARMKAAALSNRRASLPSKTVFDSALVPAVDVKGTVSPGLRWALYEGDFP
                     WVPDFRQWKKPASAHGVTPSPSVKMNGSDKRGVELTGYVKIPEDGAYTFYLTTDENKGS
                     KAFVRLHGMELIDADKTYEPGAEVSSDLGDRKNPVYLKAGLHPIRIGYVGNSGTASKLV
                     LKWEGPGLSKQEIPASAFSHGKESR"
     CDS             complement(11326..13140)
                     /locus_tag="ctg8_10"
                     /transl_table=11
                     /translation="MTQTSSFSALGISPEILEAIEVLGFDTPSSIQEQAIPAAIGGADI
                     VGLSHTGSGKTLAFAIPALECIDPEERCVQVLALCPTRELAVQICREVDKLALFMDGVS
                     AVPIYGGSSFRPQLDALRRGVQFVVGTPGRVMDLMESGALRLDGLRMLILDEADEMLDM
                     GFLEDIEHIADAMPEAKQTLFFSATMSPEISRLVSRFMKEPVQISIERPTLTVPTIEQV
                     YYEVVFSSRIEVLSRLLDTGKIKMGLVFANTKKVVDDVVDGLTARGYPVDRLHGDMPQM
                     MRERVMDSFRKGSLRLLVATDIAARGLDVDDVDAVVNFELPRDPEDYVHRIGRTARAGR
                     KGKAITFVGRRDFSLMSRIERFIGVKLTPEPVLTAVQVDQLRTESLVDDILERLKPDAV
                     LPEELKEVEAAPEAMAAALFDLLRERTHREVQPIPEDKPARRARRMPQTGEEAESPQKG
                     DSWQHKGDTVTLFMNGGRMIGLRPKDIAGLFYNTVEMEKGAVGDIRIFPKHSLIEVDAS
                     VAPLLLEALATATVCGYEVNVREDKGAPEYSGTPRSSRRNGGFRNSYRGERDRSDRSGF
                     RGNRGGFRSDRGERWGERSRRDDRKKRF"
     CDS             13334..14137
                     /locus_tag="ctg8_11"
                     /transl_table=11
                     /translation="MIQIFPSEFMDKTPNKSQSSLLGIFINILLPVLILDYCSAGPANP
                     LERPEGESFWHIGPVWSLVIALSLPLVYGIRSLAVSRKFDLMSVVGMAGVLLTGVISIF
                     VIGPEGRIHSATPWLFAGKEALIPLILAAAVVVSRSTGTPLLNMFIYTPELFDVRRIEQ
                     TVAANGEEQAYQSLLANSSWILAGTLVASSVGNFFLSLSFMSSVIRQPEAEQQVAYNAA
                     IGSITWWGFLIIGIPILAALVFIMTRLIKQLGRLTGLSRDELLLK"
     CDS             14148..15686
                     /locus_tag="ctg8_12"
                     /transl_table=11
                     /translation="MRLHTSCILAAAIALNAAWADAPRFDRIFGSHMVLPHGKNIPVSG
                     TAAPNREITVTFGNTALKTKTDSKGKWSVTLPPMPPCGTGQTLAAVQNGDSAKLEDVLV
                     GEVWLASGQSNMLFRLNQTTTAKEDIAASGDDQLRLLNNIPQAHTNNAPYSGKDFDAVT
                     TDNFYKGQWASSSPSTSGPMTAVGYYFGKKLREGLGIPVGIIHSSLGGSEIAAWLPREV
                     INANNSFRTLRGNHWLDSPLISDWVRGRARKNISPRLNQGSPDHPYKPAFLYESGIAWT
                     TPLPITGVIWYQGESDAEIIDNAQNGMLLKTMISSWRKAFRNPEMPFVMIQLPRINDPS
                     KIRAGWPEFREMQDTVAKTVPQVYSVNTIDLGSTNADVHPPFKRPVGERAGNTALNKVY
                     GKKVPCEGPAFKAFKTSGSSILVQMEQAAGLTTTDGKKPAQFEIAGTDGIYHPATAEIT
                     NRKGGTAVIRLSSPEVKSPKNARYCWNRFVTPNLVNGNQLPARPFRTDVPVLKK"
     CDS             15708..16685
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_13"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 2.1e-27, bitscore:
                     89.8, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLHLFLASLAATLSLGIAAQASPAKVACVGDSITFGSGLKPGEA
                     RYPQVLATLMGPDFDVRGFGNPGKTAGDYPGQAGRWYGSTREHKQALDFKADIYICNLG
                     INDTGRWWNPELFSKGYEALLQAWKNANPKARFFAWGLLGPDYRGPLNKKAFPGNCYPD
                     VRKYAGSDNGSAANRPEAEKLIAAVARKYKVSLFDALHPLSDHPEWYVDGLHPTEQGAR
                     RIAEITFAKLAKSLKIKQPVPRLEPGTGNVIINNPGNSGILLDGWKLTDGSNTLIFENS
                     TVIHPKDRLIIAIGPETQKDPTGPLQIKSAKSPAAFRLIPAKKY"
ORIGIN
        1 ccgcggattg tccgatccgc ggcctttttc gtccggctct ctttcaaatg cggagtttgg
       61 gcttgatgaa cgaaacttct tactgtagca acaagacatg cgtttattcg cccttcttgc
      121 aggattctcc ctttgcctga gctccacaag ctgccaatcg tacggggatt caagtgacta
      181 catccccctc gcaacgcccg ttcccccaca actctcccag ccggtttccc atgccctccc
      241 ccgaccggcc aatttcccca cacgtcccgt agccatcccc tcaagcgccc cgcgcacgcc
      301 ccgctgcgcc agtgcctgcg ttatggacgc ccttaccggc aacgtgctct tttcccacaa
      361 cggcctccag cgccgccagg tagccagcac gcagaaactc gtgacggcca tggtcgtgat
      421 gggacacggc agtctggaca aaaaagtggt catccagcct tccgatacca aggcggaccc
      481 caccaaactg ggattccggg cgggggaagt ctattcacgc cgcgaactgc tcaatgccat
      541 gatgatccgc agtttcaacg acgtagccct ggctctggcc cgcgatacgg ctggttccgt
      601 tccccgtttc gcccagttga tgaatgccaa agcccggcag atgggcatgt acaactcacg
      661 cttcgccaat cccaacggcc tcccggcgga tcaatattcc actgccattg acatggcccg
      721 ctgcgcctat tacgtgtacc gcaacccgga actgcgcaat attatctgca aacgccaata
      781 tgcctttacc cgcgccaacg gcagaacgct tctgctgaga aacaccaaca agctgctcac
      841 ccagaacccc tgggttaccg gaatgaaaac cggatacacg aacgccgccg gacgctgcct
      901 ggtttcctca gccggcgtca acgggcgcca tgtcatcgtc gtcgtcctcg gctgccatcc
      961 gtcccgtatc tggacggaat cggaaaacct gatcagatgg gctctgggaa ccgccgcata
     1021 aatgcccgtc ggcaattggt atttgacttt cacggcgtga cccgctatca gtcctgccta
     1081 tgttacaggc aggtattgta ggtctcccca acgtcggcaa atccactcta ttcaatgcgg
     1141 tcacccggac gcgcaaggcc caggcggcca actatccctt ctgcaccatt gacccgaacg
     1201 tgggtatggt aacagtcccg gatccccgcc tgcaggttct ttccgacatg tccggttctg
     1261 aaaaaatcat ccccacgctt attgaattcg tggatattgc cggtctggtc aagggagcct
     1321 cggaaggagc cggcctgggc aaccagtttc tggcgaacat ccgtgaagtg gatgccatcg
     1381 tgcaggtagt ccgctgcttt gacaatgatg atatcattca cgaactcggt tccgtggatc
     1441 ctctgcgcga cattgacatc atcaactcgg aactcattct ggcggatatc gccaccatgg
     1501 aaaagagact ctcttcccga gaacgcaagg cacgcagcgg cgacaaggaa gccaaggccg
     1561 aagtggccct catcaccaaa ctcctgcccc acctgaacga aggcaatccg gccctcaccc
     1621 ttgaaccgca gctggacgac gatgaacgca agctgctcca ttccttccag ctgctttcgg
     1681 ataaaaaaag cattttcgcc tgcaatgtca atgaagacga actggcggac gccatctcca
     1741 acccggacgc ccatccctac gtctcccagg tgaaaaaata cgtagcggaa caccataacg
     1801 cggaagccat tgtcatctcc gcccggattg aagaggaact catcgacgtc tcggaggaag
     1861 aatcccgcga attcctggaa tccctgggtg tgaaggactc cggcgtttcc gaccttatcc
     1921 gcgccgtgta ccaccttctg ggcctgcgca cctaccttac cacgggaatc aaggaaacgc
     1981 gggcctggac cattccgtcc ggggcaaaag cacctcaggc ggccggcgtt atccacacgg
     2041 actttgaacg cggttttatc gccgcggagg tagtgcacta cgacgacctg gtttcctgcg
     2101 gcggcaaggc cggagcgagg gaacacggca agctgcgcat cgaaggaaaa gaatatgtcg
     2161 tcaaagacgg ggacgtcatc gaattccgct tcaatgtcta gacggaagcg ttaccggaat
     2221 tccattgact tttactgata taaggggcag attgctcaca accttcacat cgcctcatga
     2281 ctgatacaga cgtcaaatcc acccccctgg cagctaaaca cgttgaactg ggagccagaa
     2341 tggttccttt cgccggctgg aatatgccgg tgcagtacac cggcattctg gacgaacaca
     2401 aagcagtgcg cgaaacctgc ggcatctttg acatctccca catggggcag ttcacggtag
     2461 ccggcggttc cgctgcggca tggctgaact ccatgctgac caatgacatc aacaaactga
     2521 atgtagggca ggggcaatac tccgtcatgc tcaatgacag ggccggagtc attgacgacc
     2581 tcattctgta ccggatggaa ccggaaacct tcttcgtagt ggtgaatgcc tccaagattg
     2641 atgaagactt cgcatggctt tccgcccatc aacctgcagg cgtaaccctg gaaaaccact
     2701 ccgacgaata cgtggggctg gctgttcaag gtcccgaatg cggaaaagta ttctcccgcg
     2761 tcatccccgg cgtggaactt cccccccgca atggaatctc ccgcatcacg gcggaaggga
     2821 cggatctcat tatctgccgc accggctata ccggggaaga tggttttgaa ttcttctgcc
     2881 cggctaagga aggcgtcaaa tggtttgaag cctttcttgg agcaggagcc aaaccctgcg
     2941 gcctgggcgc ccgcgacagc ctgcgtctgg aaatgtgcta tcctctgaac ggctccgacc
     3001 tctctccgga caaaacgcct ctggaagccg ggctcggatt cttctgcgcg ctggatacgg
     3061 acttcatcgg ttccgatatt ctccgggaac aaaaagccaa cggcctcagc cgtcggctgg
     3121 ccgctattga atacaccggc aagggagctc ctccccgcgc ccactatgcc gtgcacgtcc
     3181 ccggcggaga agccatcgga gaacttacca gcggcgtgct ctctccttcg ctgatgaagg
     3241 gcattgccct ggcctacctg cctgccgccc atgccaaggt cggcacggag ctggaaattg
     3301 acgtaagggg aaggaaattc ccagccgtgg tcgtaaaaaa acccttttat aaaaaaggct
     3361 gacactacgg cgcaaaaata aactgacaaa cccctcattt tactacactc tcacttcaaa
     3421 caattacatc ttatgcacga cgtaccagaa aatctgctgt attccaaaga tcacgaatgg
     3481 attgaaattg acggggacat cggcaccatc ggcatttccg accatgccca ggccgaactc
     3541 tccgatgtcg tctttgtaga ccttcccgaa gtaggcgcca ccgtcgcagc tggcgaccct
     3601 gtcgctgtcg tggaatctgt caaagccgcc agcgacgtgt acacccccgt ttcaggagaa
     3661 atcctggaag tgaacgaaga gctttccaat gatccgtccc tcattaactc cgacccctac
     3721 ggcgcaggct ggctgtacaa aatccgcctg gacgttccca cggaaacgga agatatgatg
     3781 aacgccacgg attacgagga atactgctcc tgaaccattc ttccctcccc cgccccggtg
     3841 attccatccc ggggcatttt gtttggcccg ttccgcggtc ggacgctatt accagccaga
     3901 gataccacat gaatacccac tcagattttg ccagccggca catcggcccc cagggggaag
     3961 aacgccggga aatgcttgac agcctcggct accggacgct tgacgaactc attgcggaca
     4021 tcgtccccgc agatatccgc atgaaggccc cgctggacct gcccgcagcc aaatcggaaa
     4081 cggaagccct gaaggaactc cgttccattc tgcggaaaaa caagctccta aaaaccttca
     4141 ttggccaggg ctattacggc accatcactc cctccgtcat cctccgcaat gtactggaga
     4201 accccggctg gtacacggcc tacacccctt atcaaccgga aatcgcccag ggacggctgg
     4261 aaatgctcat gaatttccag accatggtct cttccctgac agggctgccg gtagcgaacg
     4321 cctccctgct ggatgaaggc accgcagcag cagaagcagt caccatgtgc cggaatgcgc
     4381 gccccaaagc aaacaccttc tttgtggcgg acacctgcca cccccagacc atcagcgtca
     4441 tccgtacccg cgccgccttc cagggcgtta acatcatcgt gggagattgc tcctcctttg
     4501 accccgcatc catcggtgcg gatctggccg gagtgcttgt ccaatatccg gacacgctcg
     4561 gctgcatctg cgactacacg gacttctttt cccgcgtgca tgccacgggc gcgctctgcg
     4621 tcgtggcggc ggatctcatg gcccttaccg tcatccggga acccggcgcc ttcggagccg
     4681 atatctgcat cggcaacacg cagcgcttcg gcgtcccaat gggcttcggc ggcccccatg
     4741 ccgcctatat gtcctgcacg gacgctctca aacgccgcat gcccggccgc cttatcggca
     4801 tgtccataga taccctgggc cgcccggcct accgcctggc cctgcaaacg agggaacagc
     4861 atattcgccg cgacaaggcg acctccaaca tatgcaccgc ccaagtgctc ctggccgtgc
     4921 ttgccgcctt ttacaccgta taccacggcc aggaaggcct caaacgcatc ggcacggaaa
     4981 tccacttgaa aaccaaaagc ctgtacaagg cgctcacgga agccggcatt gccattgaaa
     5041 acaaaaactt ctttgacacc ctgctgctgt ccgttcccgg acaagcggac gctatggtgc
     5101 aaaaagccct ggaagccggg tataacatcc gcagggtgga tgccgaccac gcagccatct
     5161 ctctggatga aaccgcaacc tgtgcggata tagcggcact ggcctccgcc cttgcaggtg
     5221 cggaaacatc cgccacctgc gattgcgacg ctcctgcctg ggatcccgtc cacacgcgcc
     5281 agacgccttt ctgcacggaa aaggctttca actcctacca ttccgaaacg gaaatgatgc
     5341 gctacatccg ccgcctggaa tcccgggacc tggctctaaa tgaagccatg atccctctgg
     5401 gctcctgcac gatgaagctg aacgccgcct ctgaaatgat tcccatcacg tggccggaag
     5461 ccaactccct gcatcccttt gttccggcgg accagtcgga aggcatccgg gaaatgctct
     5521 ccgtcctgtc cgaccgtctg gcgaaaatca ccggctttgc cgccgtttcc ctccagccca
     5581 acgcgggcgc cgcaggggaa tatgccgggc tactggccat ccgccgctac cagaagcacg
     5641 ccggagaagg ccaccgcaat gtctgcctca ttcccacctc cgcccacgga acaaatcccg
     5701 cctcctctgc catggccggc ctcaaggtgg tacccgtcaa atgcgacgaa agaggcaaca
     5761 tcaacatggc agacctgaaa tcccaggcgg aagcccataa ggacaatctc tcctgcatca
     5821 tggtcacgta cccctccacg cacggggtat atgaacagac aatcaaggaa ctctgcgaca
     5881 tcgtccatgc caatggcggc caggtgtaca tggacggcgc caacatgaat gcccaggtag
     5941 gtctgacttg ccccggctgc attggcgcgg acgtctgcca cctgaacctg cataaaacct
     6001 ttgccatgcc gcacggcggc ggcggtcccg gcatcgggcc catcggcgta gcggaacacc
     6061 tcgtaccctt cctgcccggg cacctcacgc tgggccatga agaaggggcc gtagcgtctg
     6121 cggcgtgggg aagcgcctcc atcgccgcca tctgctggat gtacctctcc atgatggggc
     6181 cggacggcct cagggaagcc acggaaatgg ccatccttaa cgccaactac attgccaaga
     6241 aactcggaca tctcttcccg gttctctact ccggcaacaa ggggttggtg gcgcatgaat
     6301 gcattctgga tccgcgtcag ctcactcatg acgccggcct cacggtggat gacattgcca
     6361 aaaggctcat ggactacggc ttccacggcc ccaccatgtc cttccccgtt ccgggcaccc
     6421 tgatggtgga gccgacggaa tcggaaccca aaaaagaact ggaccgcttc attgaagcca
     6481 tggaacgcat tcatgcggaa atcacggcca ttatcaacgg tacggcagac aaggaagaca
     6541 acgtcctgaa aaactcgccc cataccgcag aaatggtctc tgccgacgaa tggcggcatc
     6601 cctactcccg cagtgaagcg gcttatccgg tctccggtct ccttattcac aaattctggc
     6661 cgtatgtagg ccgggtggat aatgtgtacg gagaccgcaa tctggtctgc acctgcgaca
     6721 cggtggagga attctccaag gccgtagagt tataaaaatc tcatccttcc tttcaaaaag
     6781 gctgttccat tcatttggag cagccttttt cttatgttca agaatcggat ttctaatccg
     6841 aagtcaacac tctattttga gtacaaatgg gtcatcaaaa tgaaagggga ggaaaagcag
     6901 ggtaggagaa atgtgccttt ttctttttta atacatactg cttttatgct taattgtttt
     6961 ctggatgcgt ttgtttcttc ggattagaaa tccgttgagc tacgtctcag atgagctttt
     7021 tctctgccct tactgttcct ggccttcaac agcatctttc tttttccagg gaagattccg
     7081 ctatcctcaa agggtatgga attctcttca tgatctttca tcatgtcttc ggcttatacg
     7141 ctctacccgc aggtgtggat acggcatgga ttgctcccca gcttaccaaa gccgctccca
     7201 tctttaaaat ttgcgtgccc atttttattt tcatcacggg gtacgctatg ggatggaaaa
     7261 caaattcatc cccaaccttc ggttccctca ttaaaacagg cttttcccat tactttaaat
     7321 tctggaaaat ttatttctta tgcctccttc tggctattct ggtttcctgg gcattcccct
     7381 tgcccatttt gccatccgtt gccgacatgg gttggaaaaa tggcctgctt gtcgtaacag
     7441 gattgaggcc ctgttatccc gactggtggt acatggctct tttcgcggca gccaccatgg
     7501 ccctttatcc aatctgtgcg tggatcacgc atcacattgc gcctgtcccg tccatggcag
     7561 ctctgctggg agtgtccctt ttatttcaaa gtacggccca cattcccagc ctgccgggaa
     7621 tcgcctattc cttccctcct ttcctgccct gcttcattct cggctacatg tgcgcctttc
     7681 tggcttcacg cctctctgct ctttcaattt cccaaagctt gggagcaatc ctgttgctgg
     7741 ctcttgaaat actatccatc catctcttca gtttttcaaa agccaaaacc ctgacggtta
     7801 tctttctctt caccctctgg tgtctgcctt ggataacccg gaaactccgc ctcacaccgc
     7861 tcttgacgct gctgggaact tattccgcac ttatgtggct gaatcacaga ttcattttcg
     7921 gctaccactt cagctgggac ctctatggaa cccaaagcat cagcgtagta ttcatcgtga
     7981 cgctggtctc ttcccttctg ctggccatgg ccatgcaaaa actttttaac cggatgattc
     8041 cctcaaatcc gcaaacacag tcaaaaactt tgtagcaact ttacaaggtc cggattccaa
     8101 cacctcttaa ttccaagggg gatctccgta cttattttct ccaatccggc tttccccatg
     8161 ggataaatac cacaacagca gccaccctat gaagggaacg gccagaaaaa ccaggaaaaa
     8221 gccgctcctc ccgacatcat gcagacgccg gaccatggta gccgccagcg gaatagacag
     8281 cacggcgagc accacgtaca gcagagggga aaccagctca acccacggaa ccagggacgg
     8341 gaacaaaccg cattccgcaa aagaggggac tcccgccacg gccagccacg caacccccac
     8401 tctggaaaaa acctcgtgca actccccttt cccggcacgg ccctcaaaac ggcaccatgc
     8461 cttgatgacg cgtatccagt acttcttcct gctccagccg gagtcggtgc ctccaggctc
     8521 tgaaccggga tccggcagaa cggagggctc cccatcatca tccataacag tcatggaggg
     8581 gataaaagag gccagaggcc tccagtctcc gccgggaacc ttccggacca aagtccggtt
     8641 ggacaggcgg ccgaggttac gggcccgcag caaaagcacc aggtcaaccg ggcctttgga
     8701 agaaccgtca attgcctgat actcgtacag atcgctcatg gggacgctta cctggattcc
     8761 ttcccgtggc tgaaggcgga ggcgggaatc tcctgcttgg acaaaccggg accttcccac
     8821 ttcaaaacca gtttggaggc agtaccggag ttccccacat agccgatgcg gatgggatga
     8881 agtccggctt tcaaataaac gggattcttc cggtcaccca gatcggagga gacctcggcc
     8941 cccggctcat aagttttgtc cgcgtcaatc aattccatgc cgtgcagacg gacaaaagcc
     9001 ttgctgccct tattttcatc cgtggtcaga taaaacgtat atgctccgtc ctctggaatc
     9061 ttcacatatc ccgtcagctc cacaccgcgc ttgtccgaac cgttcatttt cacggatggg
     9121 gaaggcgtca cgccatgggc ggaagcaggc ttcttccact ggcggaaatc cggtacccag
     9181 ggaaaatccc cctcatacaa ggcccatcgc aacccgggag aaacggttcc cttcacatcc
     9241 acggcaggca ccagcgcaga atcaaacact gttttggaag gaagggaagc ccggcgattg
     9301 gacaaagcgg cggctttcat gcgggcctga agttccggct tggaggatgc gagatctttg
     9361 ctttcctgcg gatcattcaa agtatcaaaa atcatgaaat ccttgtccgc atccttcacc
     9421 cccatgcgca agcctttcaa tccatccaca aaaacaatct gctgctggcc tcgctgcgct
     9481 cccttgtgtt cgcccaggaa atccttatac tccggcgttt tgccggcgaa attatattcg
     9541 gcataaacaa tgccgggctt ctgctggtcc gcatgaccgg tcagcgtcgg cagcagggaa
     9601 acgccgtcac tgcgggctgg aaccggcacc ccggcgacat ccgccagcgt agccagccag
     9661 tcatggaact gtccaggatg caggctgatc tgccctttgg gaatgcgggc gggccagcgt
     9721 accagcgtag gcacgcgcat gcctccttcc cagcaatcgc gcttaatacc gtccatcatg
     9781 ccataactct tgaaaaactg cggattttgc gctccgtgcc agtgcctggg gtcggagccg
     9841 ccctcattgt gggggccatt gtcggacgtg aagacgatca tcgtattatc gtcaatcttc
     9901 aaatctttca gcagacggat caaatcagcc acggcatcgt ccacgcggcg gatcatggtg
     9961 gaatgacgtt tggccacatc attcgggaaa cgggaattgt ccggatgaat ataggtatcc
    10021 ttattctttt ccgccctggc gtcaaaagcc gtattcacgg attccgtgcc ttccttcttt
    10081 acccattgca ggcctccttt caatccgccg ccggaaggat agggaacccc cggaaccacc
    10141 agattgccgt ggggcgccgg aaaagccagg tacaggaaaa acggctttcc ggtcttgcgg
    10201 gcggacttgc gctggtccac aatccactgc ttggcgcggg cggcaaataa atccgtggaa
    10261 taagccgtct ggggcacctg gtccttgata tttttccact cgggattgga agcgtaaccg
    10321 ttgtattcga aaacgtcacg ggattcggaa ggatagtgaa aatgccctgc caaatggtcc
    10381 aggataccgt aaaaataatt gaatccccgc tgatgggggc cggcggtcat gggcacatgg
    10441 ctctggcctc cgccgcccac accccatttg ccaatggcag cagtatcata cccggcatca
    10501 cgcatcacgg tacccagcgt atgggaatct tcaataggct ggtcgaaacg gttgtttctc
    10561 accacgcggg aattcccctg gtgcacccct agcagcaggg aggcgcgcgc cggagcgcaa
    10621 accggagcgg cggaataatg acggcgcagc tgaatcccct cccgagccag agcggacagg
    10681 gcaggagtct tgaactcgtt ctttctctcc accgtccggc cattcagctt ctgctggctc
    10741 cagttggaat ccagatcacc ccagcccatg tcgtccacca gaatgaaaat aacattgggt
    10801 tttgaagttt tgacagaccg ggcagccggc ttcgttgcct gcccggaagc acccatgcac
    10861 ggaaccaggg aagtcagaag aacggatagt aaagatacca gcttcatgat tcaaagaaaa
    10921 tagactctaa aaaagacgtt aaaataaagc gttatcttac atgaattttc tcatccctca
    10981 agaaaattac gaggaaaggg cacagaggat tgaatcgcca gtattatcgg caaaaaacat
    11041 cagggaacca gccttcacag ccggaacaac tacaacccgc catactgcac caatgagcgg
    11101 cttttctggc tgaagccagg aatgggagaa aattcctcct gcattcccgg cgccccggtc
    11161 accagccccg cccggccatg ctttatcctg aataaaacgg cagtcccccc gccgggcaga
    11221 aaatacagaa accggcggaa acagcaatca tgaaccggaa cgttccaaaa tgtccgcgcc
    11281 aattccggaa cagcgttaat aaccctgtcc ggaatagcga aggcatcaga aacgcttctt
    11341 cctgtcgtcc ctgcgggaac gttcgcccca gcgttcgccg cggtcactgc ggaagccccc
    11401 gcggtttccc ctgaatccgc tccggtcact gcggtcccgc tctccgcggt aactgttgcg
    11461 gaatcctcca ttgcggcggg aagagcgcgg agttccggaa tattccggag cccccttgtc
    11521 ttcacggaca ttaacttcat agccgcagac ggtagccgtc gccagggcct ccagaagcag
    11581 gggcgccacg gaagcgtcca cttctatcag ggaatgcttg gggaaaatcc ggatatcgcc
    11641 cacggctccc ttttccattt ccaccgtatt gtaaaataac ccggctatgt ctttgggccg
    11701 caagccaatc atccggcctc cattcataaa cagcgtaacc gtatccccct tatgctgcca
    11761 ggaatcaccc ttctgcgggc tctccgcctc ctccccggtc tgcggcatac gccgcgccct
    11821 gcgggcgggc ttgtcttccg gaatgggctg cacttcccgg tgcgtacgtt cccggagcaa
    11881 gtcaaacagg gccgcagcca tggcctccgg cgcagcctcc acttccttca attcctccgg
    11941 cagcacggca tccggcttga gacgttccag gatatcatcc accagggact ctgtccggag
    12001 ctggtccacc tgaacggcag tcaacacagg ttccggagtc aacttaacgc cgatgaaacg
    12061 ttcaatgcgg ctcatcaggg aaaaatcacg gcgccccaca aaagtgatgg ccttcccctt
    12121 gcggccggcg cgtgccgtgc ggccgatgcg gtgcacgtaa tcctccggat cacgcggcaa
    12181 ttcaaaattc accacggcat ccacatcgtc cacatccagg ccgcgagcgg caatatccgt
    12241 cgccaccaga aggcgcaggc tccccttgcg gaaggaatcc atcacgcgct ccctcatcat
    12301 ctggggcata tccccatgaa ggcgatccac cggataaccg cgggccgtca gaccgtccac
    12361 cacgtcatcc accacctttt tggtattggc gaacaccagc cccattttaa tctttccggt
    12421 gtcaagcagc cggctgagta cctcaatccg ggaggaaaac accacttcgt aataaacctg
    12481 ttcaatggta ggcaccgtca gcgtaggccg ttcaatggaa atctggacgg gctccttcat
    12541 gaacctgctc accaggcggc tgatttccgg agacatggta gcggagaaaa acagggtctg
    12601 cttcgcttcc ggcatagcgt ccgcgatatg ttcgatatct tccagaaacc ccatatccag
    12661 catctcgtcc gcttcatcca gaatcaacat gcggagacca tccagcctta gcgccccgga
    12721 ctccatcagg tccatgacgc gtccgggcgt tcccaccaca aactgtaccc cgcgcctcag
    12781 ggcgtccagt tgcggacgga aagaagagcc tccgtaaatg gggacggcgg aaacaccgtc
    12841 catgaacaaa gccagcttgt ccacctcccg gcaaatctga acggccagtt cccgagtagg
    12901 acagagggcc agcacctgaa cgcagcgttc ctcaggatca atgcactcca gggccggaat
    12961 ggcaaaggca agcgtcttcc cggagcccgt atgggacaac cccacaatat cggcccctcc
    13021 gatcgcggcg ggaatcgcct gctcctgaat ggaggaaggg gtatcgaagc cgagcacttc
    13081 gatagcctcc agaatctccg gtgaaatacc aagagccgaa aaagaagatg tttgagtcat
    13141 gggggaaaaa tgatctgtca gagtcacggg agaagctgaa cattattccc tcccgtgtcc
    13201 agccaaaaga acggaagata ccgtagatgc cacgatttcc gcaaagccgc ctgcgaataa
    13261 aaaaaacgga tctccccgct tctggtcttt actgtcacac acggggttgc aacttgcagg
    13321 ggcgcattcg cgtatgatac aaatatttcc ctccgaattc atggataaaa cgccaaacaa
    13381 atcacagtcc tccctgctgg gaattttcat caacatcctc ctcccggtac tgattctgga
    13441 ctactgcagc gcgggccccg ccaatcccct ggaacgtccg gagggagaaa gtttctggca
    13501 catcggcccg gtatggtccc tcgtcatcgc cctttccctc cccctcgtct acggcatccg
    13561 ttccctggcc gtctccagga aatttgacct gatgtccgtc gtaggcatgg ccggcgtgct
    13621 gctgacgggc gtcatcagca tcttcgtcat cgggccggaa gggcgcatcc acagcgccac
    13681 accctggctg ttcgccggaa aagaagccct gatccccctc atcctggcgg cagccgtcgt
    13741 cgtctcccgc tccaccggca cccccctcct caacatgttc atctacacgc cggagttatt
    13801 cgacgtgcgc aggatagaac aaacggtggc cgccaacggc gaggaacagg cctaccagag
    13861 cctgctggca aactcgtcat ggattctggc gggcacattg gtcgcatcct ccgtcggcaa
    13921 tttcttcctg agcctctctt tcatgtcctc cgtcatacgc cagccggaag cggaacagca
    13981 agtggcctac aatgccgcta tcggcagcat cacctggtgg ggcttcctga tcatcgggat
    14041 ccccattctg gcagctcttg tcttcatcat gacccgcctg attaaacagc tcggcaggct
    14101 gaccgggctc tcacgggacg aactccttct caaataatcc tcaaaccatg cgcctccata
    14161 cttcatgcat cctggctgcc gccatcgccc ttaacgcagc gtgggcggac gccccccggt
    14221 tcgaccggat tttcggttcc catatggtac ttccccacgg aaaaaacatt cccgtttccg
    14281 gcacggccgc ccccaacagg gaaataaccg tcacttttgg aaacactgct ctgaaaacaa
    14341 aaaccgattc caaaggaaaa tggagcgtca cgctgcctcc catgcctccc tgcggcacag
    14401 gccagacgct ggcggccgtg caaaacggag actccgccaa attggaagat gtgctcgtgg
    14461 gggaagtgtg gctggcttcc ggccaatcca acatgctgtt ccgcctgaac cagaccacga
    14521 cggccaaaga agacatagcg gcttccggag atgaccagct ccgcctactc aacaatattc
    14581 cgcaagccca caccaacaac gccccctact ccgggaaaga ttttgacgcc gtcaccacgg
    14641 acaacttcta taaagggcaa tgggcctcca gctcaccctc cacttcaggc cccatgactg
    14701 ccgtgggcta ctatttcgga aaaaaactcc gcgaagggct gggcattccg gtaggcatca
    14761 ttcactcctc cctagggggc tcggaaatcg cagcgtggct ccccagggaa gtcattaatg
    14821 caaacaacag tttccgcacc ctgcgcggca accactggct ggactccccc cttatctccg
    14881 actgggtaag gggacgggcc agaaaaaata tctctccgcg tctgaatcag ggatctccgg
    14941 accatcccta caagccggcg ttcctttacg aatccggcat tgcctggaca acaccactcc
    15001 ccatcacagg cgtgatctgg tatcagggcg aatccgatgc ggaaattatt gacaacgccc
    15061 aaaacggcat gctgctgaaa accatgatct cctcctggag aaaagctttc cgcaacccgg
    15121 aaatgccctt cgtcatgatc cagctccccc gcattaacga tccgtcaaaa atccgtgccg
    15181 gatggccgga attccgcgaa atgcaggaca cagtggccaa aaccgtcccg caggtttaca
    15241 gcgtcaacac cattgatctt ggctccacca atgccgacgt tcatcctccg ttcaagcgcc
    15301 ctgttgggga acgtgcagga aatactgccc tgaacaaggt ttacggtaaa aaggtcccct
    15361 gtgaaggccc tgccttcaag gccttcaaga cctccggttc cagcatcctg gtccagatgg
    15421 aacaagctgc cggactgacc accacggacg gcaagaaacc ggcccagttt gaaattgccg
    15481 ggacggacgg aatttaccat cccgccacgg cggaaatcac aaacaggaaa ggcggcacag
    15541 ccgttatccg cctctcctcc ccggaagtaa aatcccccaa aaacgcccgg tattgctgga
    15601 accgtttcgt gacccccaac ctggtcaacg gcaaccagct ccctgcccgt cccttccgga
    15661 cggacgtacc cgttctgaaa aaataactct taccacgcca tcattccatg aaccttcatc
    15721 ttttccttgc ttccctggca gccacgctct cactgggcat tgcggcacaa gcttctcccg
    15781 ccaaagtggc ctgcgtaggg gacagcatca ccttcggctc cggccttaaa cccggagaag
    15841 cccggtatcc gcaagtgctc gccacgctaa tgggcccgga ctttgacgtc agaggattcg
    15901 gcaatcccgg aaaaacggcg ggcgactatc cgggccaagc aggacgctgg tacggcagca
    15961 ccagggaaca caagcaagcc ctggacttca aggcggatat ttatatttgc aaccttggca
    16021 ttaacgacac aggccgatgg tggaaccccg aactattctc caaaggctat gaagcgctgc
    16081 tccaggcatg gaaaaacgcc aatcccaaag cacggttctt tgcctggggc ctgctggggc
    16141 cggactaccg cggcccgctc aacaaaaagg cattccccgg caactgctat ccggacgtac
    16201 gcaaatatgc aggctcggac aacggctccg ccgccaaccg tccggaagcg gaaaaactga
    16261 ttgccgccgt agcacgcaag tacaaagtca gtctctttga tgcgctgcac ccgctctccg
    16321 accatccgga atggtatgtt gacgggctgc atcctacgga acagggcgca cggcgtattg
    16381 cggaaatcac cttcgccaag ctggcaaaaa gcctcaagat taagcagccc gtccccaggc
    16441 tggaaccggg taccggcaac gtgatcatca acaaccccgg taattccggc attcttctgg
    16501 acggatggaa attgacggac ggctccaata cgctcatttt tgaaaattcc accgtcatcc
    16561 atcccaagga caggcttatc atcgccattg gcccggagac ccaaaaagac ccgaccgggc
    16621 ccctgcaaat caaatccgcc aaatcccccg cagctttccg cctcattccc gcaaaaaaat
    16681 attaaaaacc actggaacag tttcattggg aacatacgga actgttgcat gttcccaaat
    16741 acccggcgca ctcta
//
