LOCUS       c00145_gnlPro..         9900 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JOCDJJMO_145.
ACCESSION   c00145_gnlPro..
VERSION     c00145_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 09:18:21
            Original ID  :: gnl|Prokka|JOCDJJMO_145
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9900
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..9900
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2568:7130]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2569..7130
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..9900
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..9900
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(3..1148)
                     /locus_tag="ctg145_1"
                     /transl_table=11
                     /translation="MRENAFVEAWKTQHRRVSMILGLTLLCAPSAISVYAENGVNDITV
                     QAVMQTKTVKGTVLDENGEPLIGVSIVVKGTSTGTITDFDGKFSINLPAGSKELVVSYI
                     GYKEQAIIVSGNAPLNIKMVPDTQALDEVVVIGYGTVKKRDLTGAVASVKSEDITMNPG
                     VNPMDALQGKIAGLDITNSSGQAGSSPTVQLRGTRSLQLDEDGNISSDAFKPTYIIDGM
                     PGDIATLNPNDIESIEVLKDASSTAIYGSSGANGVIIVTTKGSKSGKPVINFNAYAGTT
                     MGARVPKMRTGDSYINYIKDSYKPVGTTNEEEIFGERYDAIKNNQWVNWGDEVLHSGLK
                     QNYSISVAGGTEKTKAYFSLNYTDEKSMYENDDYKVYSTRVR"
     CDS             1397..2395
                     /locus_tag="ctg145_2"
                     /transl_table=11
                     /translation="MPLKLTTYYRGKDIPDLPGTNTFHSKELFQIYESTPGYTPLLIVA
                     TEEGRPVARLLAAIRKTKKWLPSSLVKQCVVYGAGEFLDTSLPASKEKEEEIFGEMLEH
                     LTQEASRTCILIEFRNLDNSMFGYRFFRKNDFFPVNWLRVRNSLHSTQKAEDRFSPSRI
                     RQIRKGLKNGAKVVEAHTVEEIKEFSRMLHKVYSSRIRRYFPANDFFRHMNSMLIRGKQ
                     AKIFIVKYKEKIIGGSVCIYSGENAFIWFSGGMRKTYALQSPGILAVWKALEDAHERGF
                     RHMEFMDVGLPFRKHGYRDFVLRFGGKQSSTRRWFRISWPWLNNLLVKFYV"
     CDS             2569..2973
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_3"
                     /sec_met_domain="Glyoxalase_4 (E-value: 9.5e-25, bitscore:
                     76.4, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGETKIELLEPTCPESTIAKFIENKGAGVHHVAFAVEDGVANALAEAESKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
     CDS             3004..4557
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_4"
                     /sec_met_domain="CT_Btheta (E-value: 3e-291, bitscore:
                     955.2, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIERRAVARIGGGEKAIAKQHEKGKYTARERIAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYLFAQDFTVTAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAKTEEEGLALIRTLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNDIIPDSPN
                     KPYDMYEVISAIVDNGEFLEIQKDYAKNIIIGFARFNGQSVGIVANQPKFLAGVLDSNA
                     SRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKDQENPAQFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLSNPAKKHGNIPL
                     "
     CDS             4589..5509
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_5"
                     /sec_met_domain="OAD_gamma (E-value: 2.5e-15, bitscore:
                     46.2, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLLLLIGLTSCGEQKSNNKLLLNEVLIDNQNNFQD
                     DYGLHSAWIEIFNKSYGSADLAACLLKVSSQPGDTVTYFIPKGDILTLVKPRQHALFWA
                     DGEPNRGTFHTSFKLNPETANWVGLFDSGRKLLDQVVIPAGTLGPNQSYARISDGAADW
                     EVKGGSKDKYVTPSTNNKTLDSNAKMEKFEEHDSVGIGMSISAMSVVFCGLILLFIAFK
                     VVGKVAVNLSKRNAMKAKGIDKVEAKELSQAPGEVYAAISMALHEMQDEVHDVEETVLT
                     ITRVKRSYSPWSSKIYTLRENPNRK"
     CDS             5534..5968
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 66.7; E-value:
                     4e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_6"
                     /sec_met_domain="Biotin_lipoyl (E-value: 5.9e-22, bitscore:
                     66.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNSYKVTIGDIEDNIAHVEVNGTHYKVEMEKQPKAT
                     PKPAVVRPMPNSPAAPTTPVVKPAAPSTGKSGVKSPLPGVILDIKVNVGDTVKRGQTII
                     ILEAMKMENNINADKDGKVTAINVNKGDSVLEGNDLVIIE"
     CDS             5970..7130
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg145_7"
                     /sec_met_domain="OAD_beta (E-value: 9.6e-154, bitscore:
                     500.7, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFINFLGNNLADFWTYTGFANATGGHIAMIIIGLGFIYLAVAK
                     EFEPMLLIPIGFGILIGNIPFNMDAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYMIALEMGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRLLTTKHERVIRMKPPRAVSHTEKVIFP
                     IIGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDVITILLGLTVGAS
                     TQASEFLTLDSIKIFALGALSFIIATASGVIFVKIFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             7344..8678
                     /locus_tag="ctg145_8"
                     /transl_table=11
                     /translation="MKRIILLAFLCTTTLVMAQRINHVQEAIANYDYEAALTLIAKEKP
                     TIPLLLQKGKAQRGLGMNTEALSTYQEIITNDTANTRAYIEAAECCRSLAKYQQALKYY
                     EQALDLNPENKYVRIQYIGLLLSLQKFQDALGESSLMTEKDSSAIALHLQAQSFEGMGE
                     LLPATGCYYNIQEKYPDDYLAAAKLAALNIAGSYFNEAIEATEKYRQIDTTNIAVNRQN
                     ALAYCLNKDYPTAIQRYEYLVSQGDSSFHTCYYLGISYYAEEKYYEAHDFLEAARKHDP
                     ENVNLLYYLGRACAKTSWKKLGVEYLEKALDLTIPKDSNMVRLYIGMTDCYKMAQMPKE
                     QIESIRERYRKYDKQNHKLLYDMAFIYFYSLKDKKNTERCLEAFLKTRPKEDKEEEAKL
                     NERGELVLGTKNYYNAAANWLKDIQSKQKIEDFFLGGNVPAQKPE"
     CDS             complement(8757..9761)
                     /locus_tag="ctg145_9"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTRDMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCAHPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYEENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSDHHT
                     YTDPEEVIDFATRTGCDSLAISIGTSHGAYKFTPEQCHIDPATGRMVPPPLAFEVLDAV
                     MEKLPGFPIVLHGSSSVPEEEVETINKFGGALKAAIGIPEEELRKAAKSAVCKINIDSD
                     SRLAMTAAIRKTFAEKPAEFDPRKYLGPARDNMEKLYKHKILNVLGSDNKLAE"
ORIGIN
        1 atacggacac gggtagagta cactttatag tcatcattct catacatact cttctcatca
       61 gtatagttca acgagaaata ggctttcgtc ttctcagtac ctccggcaac ggaaatacta
      121 taattctgct tcaaacctga gtgtaatact tcatctcccc agtttaccca ttggttgttt
      181 ttgatggcat cgtatctttc accgaaaatt tcctcctcat tagtagtacc gacaggctta
      241 taagaatctt ttatataatt aatgtatgag tcacccgtac gcatcttagg aactcgggca
      301 cccatagtcg ttccggcata agcattaaaa ttgatgaccg gttttccact cttggatcct
      361 ttcgtagtca cgataataac accattcgca ccacttgaac cgtagatagc tgtagaagat
      421 gcatctttca gtacttcgat agattcaata tcattgggat tcaaggtagc aatatcaccc
      481 ggcataccat cgataatata agtcggctta aatgcatctg aagagatatt accatcctca
      541 tccaactgta aagagcgggt accacgcaac tgaactgtcg gtgacgaacc tgcctgacct
      601 gaagaattag tgatatccag acctgcaatt ttaccttgca gcgcatccat cggattcacg
      661 cccggattca tggtgatatc ctctgatttc acagaagcaa ccgcacctgt caaatcacgt
      721 ttctttaccg taccgtaacc gatgaccact acctcatcca aagcctgtgt atccggaacc
      781 atctttatat tcagcggggc atttccgctc acaatgatag cctgttcttt atatccgata
      841 taagaaacaa ccagttcttt acttccggcc ggaagattaa tggagaactt accgtcaaaa
      901 tcagttatcg tacctgtact tgtacctttc accacaatag aaacaccgat caacggttct
      961 ccattttcat ctaaaacagt tcctttcact gtctttgtct gcatgacggc ttgcacagta
     1021 atatcattca caccattttc tgcataaaca gatatggcag aaggggcaca caataaagtc
     1081 agccctaaaa tcatggaaac gcgtctatgc tgtgtcttcc acgcttcaac aaatgcattc
     1141 tctctcattc gttttaattt aaagttaata ttaattttcc tttgtttagt aaaatacaat
     1201 tagcataatc ttttatatag acgtttccat tttacttctg tactcacaaa ggacgacaat
     1261 aatacaaaaa ttcgcttttc caagcctttt tttcctcaaa tatatgcaaa ggataaaaag
     1321 acaaatttta ggctaagcca acaaattctc ttttttattg ttgaatgaag aataaaaagt
     1381 gtaaatttgt atttggatgc cacttaaact aacaacatat tatcgcggaa aagacattcc
     1441 tgatttaccg ggaaccaata cttttcattc caaggagttg tttcagatct atgaatcgac
     1501 tccgggatat accccgctac tgatagtggc aacagaagaa ggcagacctg tagcacgcct
     1561 gcttgccgcc atacgcaaga ccaaaaagtg gcttccctcc tctcttgtca aacaatgtgt
     1621 ggtatatggt gcaggtgaat ttctggacac ttctctaccg gcaagtaaag agaaggagga
     1681 agaaattttc ggtgaaatgc tggagcatct cacacaagaa gcatcacgca cctgcattct
     1741 tattgaattc cgcaatctgg ataattccat gttcggttac cgtttcttcc gaaagaacga
     1801 cttttttccg gtcaactggc tgcgtgtccg taactctctg catagtacgc agaaagcgga
     1861 agaccgtttc agcccatcac gtatccgtca gatccggaaa gggctcaaaa acggagccaa
     1921 agtagtagaa gcccatacgg tggaagagat taaggaattc tcgcggatgc tgcacaaagt
     1981 ttattcttca cgaatacgga gatatttccc tgccaatgac tttttccgcc acatgaacag
     2041 catgcttatc agaggaaaac aggcaaaaat attcatcgta aaatacaagg aaaagattat
     2101 cggcggctcc gtctgcatct attccggcga aaatgctttt atctggtttt caggaggaat
     2161 gcgaaagacc tatgcactgc agtcacccgg catactggca gtatggaaag cacttgaaga
     2221 tgcccatgaa cggggattcc gtcacatgga gttcatggat gtaggacttc ccttccgcaa
     2281 gcatggttat cgtgatttcg tactccgttt cggaggcaaa caaagcagta cccgccgctg
     2341 gttccgtatc agctggccat ggctgaataa tcttctggtc aagttttatg tctaaatgta
     2401 atctcaagat tacaaaaccc gtctttgtca cccatccgga gcatttttta tgctttattc
     2461 cccaataatt aaatgcagaa atatttcttt attagacaag aaatgtcttt ctttgtgctg
     2521 ttttatgcca tataagcaca taattaaacc atataaaaaa atatagttat gaagatttca
     2581 cacattgagc atctgggcat tgctgtaaaa agcatcgaag aagcccttcc ttactacgaa
     2641 aacgtattgg gtctgaaatg ttacaacatc gaaacagtag aagatcaaaa agtaagaacc
     2701 gcttttttaa aggtaggtga aacaaaaatc gaattgttgg agccgacttg ccccgaaagc
     2761 accattgcta aatttattga aaacaaaggt gcaggtgttc atcacgtagc atttgccgta
     2821 gaagatggcg tagctaatgc tttggcagaa gcagaaagca aagaaatccg tctgattgac
     2881 aaggctcccc gcaaaggtgc cgaaggtctg aacatcgctt tccttcaccc gaaatcaaca
     2941 ctgggtgtgc tgacagaact ctgcgaacac taatcataaa ctctaaaaaa acaacaagaa
     3001 ctcatgagta atcaacttga aaaaattaaa gagcttattg aacgccgtgc cgttgcacgc
     3061 atcggaggcg gcgaaaaagc aattgcgaag caacatgaaa aagggaaata cacagcgcgt
     3121 gagcgtatag ccatgctgtt ggatgaaggt agcttcgaag aaatggacat gttcgttgag
     3181 cacagatgca cgaacttcgg catggagaaa aagcactatc cgggtgatgg tgtagtaacc
     3241 ggttgcggta ctatcgaagg tcgtctcgta tatctttttg cacaggactt taccgttact
     3301 gcaggttcac tgtcggaaac aatgtcactg aagatctgta agattatgga tcaggcaatg
     3361 aagatgggtg ctccttgtat cggtatcaat gactcgggcg gtgcacgtat ccaggaaggt
     3421 attaacgctt tggcaggtta cgcagaaatc ttccagcgca atatcctcgc ttcgggtgtc
     3481 attccgcaga tttccggtat cttcgggcct tgtgccggcg gtgctgttta ttctccggca
     3541 ctgacagact tcacactgat gatggaaggt acttcttata tgttccttac aggtccgaaa
     3601 gtagtgaaaa ctgtaaccgg tgaagacgta agccaggaaa acctcggcgg agcaagcgtt
     3661 cactctacca aatcgggtgt tactcatttc actgccaaaa cagaagaaga aggtctggca
     3721 ttgatccgca cacttctgag ctatattcct caaaacaacc tcgaagaagc tccatacgtg
     3781 gattgcacag atccgatcga ccgtctggaa gattctctga acgatattat ccccgacagc
     3841 cccaacaaac cgtatgatat gtacgaggtt atcagcgcta tcgtagacaa cggcgaattc
     3901 ctggaaatcc agaaagacta tgccaagaat atcattatcg gttttgcccg tttcaacggt
     3961 cagtctgtag gtattgtagc caatcagcct aaattccttg ccggtgtact cgacagcaac
     4021 gcatctcgca aaggcgcacg tttcgttcgt ttctgcgatg ctttcaatat ccctatcgtg
     4081 tcgttggtag acgtaccggg attccttccg ggaacaggtc aggaatacaa tggcgtcatc
     4141 cttcatggtg ccaaactgct gtatgcttac ggtgaagcta ctgtacctaa agtaacaatc
     4201 acattgcgta aatcttacgg tggttctcac atcgtgatga gttgtaaaca acttcgtggt
     4261 gacatgaact atgcttggcc aacagctgaa atcgctgtaa tgggtggtgc aggtgcagta
     4321 gaagtattgt acgcgcgtga agccaaagac caggaaaatc cggctcagtt ccttgccgaa
     4381 aaagaagcag aatatacaaa actgtttgcc aacccttata atgcagctaa gtatggttac
     4441 atcgatgatg tcatcgaacc ccgtaacaca cgtttccgcg tgatccgtgc tttgcagcag
     4501 ttgcagacta agaaactgtc taatccggcg aagaaacatg gtaatattcc gttgtaatcc
     4561 aacttttcac attaaaacaa gaacgattat gaacaaaacc aaaatcggaa tattcctttc
     4621 tctgctgttg ctgattggat tgacttcctg cggagagcaa aagtcgaaca ataagctatt
     4681 gctgaatgaa gtcctgatag acaatcaaaa caactttcag gatgactacg gcttgcacag
     4741 tgcatggatt gaaatattca acaaatcata cggtagcgca gacttagcag cttgtttatt
     4801 gaaagtaagc agccagccgg gcgatacagt aacctatttt atcccaaaag gtgacatact
     4861 tacattagta aagccacgcc aacatgcgtt attttgggca gatggcgaac ctaatcgtgg
     4921 aaccttccat accagcttca aactgaatcc cgaaacagcc aattgggtcg gtctttttga
     4981 ttcaggcaga aagctacttg atcaagttgt cataccagca ggaactttag gtcccaacca
     5041 gtcttatgca cgcataagcg acggagcagc agactgggaa gtaaaaggcg gaagcaaaga
     5101 caaatacgta accccgagca cgaacaacaa aacccttgac agtaatgcca agatggaaaa
     5161 gttcgaagaa catgactcag tcggtatcgg tatgtctatt tcagccatga gcgtagtatt
     5221 ctgcggattg attcttctct tcattgcctt caaggtggta ggtaaagttg ctgtcaacct
     5281 gagcaaacgc aatgcgatga aggctaaagg catcgataaa gtcgaagcga aagagctttc
     5341 acaggctccg ggtgaagttt atgctgctat ttcaatggca ttacacgaaa tgcaggatga
     5401 ggtacacgac gtagaagaaa cggtgctgac catcactcgt gtgaagcgca gttattcacc
     5461 gtggagttcg aagatttaca ccttgcgtga aaatcctaac agaaagtaaa tcattcccta
     5521 aaaagataaa acgatgaaag aatataaata taaaatcaac ggtaactcat acaaagtaac
     5581 catcggagat attgaagata atatcgctca tgtagaagtg aacggtacgc attacaaagt
     5641 agaaatggag aaacaaccga aagctactcc caaaccggca gtagtacgcc ctatgcctaa
     5701 ctcaccggct gctcctacca caccggtagt aaaaccggct gctccttcta ccggcaaatc
     5761 aggcgttaag tccccactgc caggcgttat ccttgacatc aaagtaaatg taggtgatac
     5821 agtgaaaaga ggacagacta tcattatatt ggaagccatg aagatggaaa acaatatcaa
     5881 tgcagacaaa gacggtaaag tgactgccat caatgtcaac aagggagatt ctgttcttga
     5941 aggtaatgac ctcgtaatta ttgaataata tgggagattt tattaacttt ttaggaaata
     6001 accttgccga tttctggacc tacacgggat ttgccaacgc gacaggtgga catattgcta
     6061 tgatcattat cggtttaggc tttatttact tagctgtagc caaagagttc gagccgatgt
     6121 tgttaattcc tatcggattc ggtattctga tcggtaatat acctttcaat atggacgccg
     6181 gactaaaagt cggtatatat gaagaaggtt ctgtattgaa catattgtat cagggagtaa
     6241 cgtccggctg gtatccaccg ctcatcttct taggtatcgg tgccatgaca gacttctcgg
     6301 cgctaatctc caatccgaag ctgatgctga tcggtgcggc tgcccagttt ggtatcttcg
     6361 gtgcatacat gatcgcattg gaaatgggat ttgacccgat gcaggccggt gctatcggta
     6421 tcatcggtgg agcagatggt ccgacggcta tcttcctttc gtccaagctg gcacctaact
     6481 taatgggagc cattgcggta tccgcctact cctatatggc gttagttccg gtgatacagc
     6541 cgcctatcat gcgtctgctc accaccaaac acgaacgcgt tatccgtatg aaaccgccac
     6601 gtgccgtttc tcatacagag aaagtgattt tcccgattat cggtctgttg ctgacctgct
     6661 tcctggttcc ttccggtctg cctctgctgg gtatgctgtt cttcggtaac ctgttgaaag
     6721 aaagtggtgt aacccgtcgt ctggctaaca cagccagcgg tccgctgatt gacgttatca
     6781 ctatcctgtt aggtttgaca gtaggtgcct ctactcaggc ttccgagttc ctgacactcg
     6841 actccatcaa gatctttgcc ctcggtgcac tgtcatttat cattgctacc gcatcaggtg
     6901 tgatcttcgt taagatcttc aacctcttcc tcaagaaggg caataagatc aatccgttga
     6961 tcggtaatgc aggtgtatct gccgttcccg actctgcacg tatctcacaa gttgtcggtc
     7021 tggaatatga tccaaccaac tacttgctga tgcacgctat gggtccgaac gtagcaggtg
     7081 taatcggttc ggctgttgct gccggtatcc tgttaggatt cttaatgtag ggacaaggtg
     7141 cccctgtcag gcttccattc ggaatgccgg gacaaaatat taggtgcgga tattgctgtt
     7201 ttagatgcaa tatccgcact tatcattatg ttatcttctc ttatcattcc gttaatctat
     7261 tccaaaaagg ctacgaataa ttcgtaaata cgatattttt tagcatcttg cgtctttgtt
     7321 acgacacact aaaataaata tttatgaaac ggattattct cctcgccttc ctttgtacca
     7381 ccaccctggt gatggcgcag cgcatcaatc atgttcagga agcaatagca aactacgatt
     7441 acgaggcagc tctcactctc attgccaaag aaaagccgac aattccccta ctcttgcaaa
     7501 aaggtaaagc acaacgggga cttgggatga atacagaagc actttccact tatcaggaaa
     7561 tcataaccaa tgacactgcc aatacccgtg catatatcga agcagccgaa tgctgccgtt
     7621 cattggccaa ataccaacag gcactgaaat attatgaaca ggcactcgat ctgaatccgg
     7681 aaaacaaata tgtgcgtatt caatacatcg gactactgct ctctttacag aagtttcagg
     7741 atgctttagg agaaagtagt ctgatgacag agaaagacag ttccgccatc gccttgcatc
     7801 tgcaggccca aagtttcgaa ggtatgggag agcttctccc cgccacgggg tgctactata
     7861 atatacagga gaaatacccc gacgactatc ttgccgccgc caagctcgcc gcactgaaca
     7921 tagccggttc ttatttcaac gaagcaattg aagccacgga gaaatatcgg cagattgaca
     7981 ccaccaacat cgctgtcaac cgccagaatg cactggcata ttgtctgaat aaggattatc
     8041 ctaccgctat ccagcgttat gaatacctgg tgagccaggg cgacagttct tttcatacct
     8101 gttattatct gggtatcagc tattatgcgg aagagaaata ttacgaagca catgactttc
     8161 tggaagccgc ccgaaaacat gatcctgaaa acgtaaacct gctttattat ctcggccgtg
     8221 cctgcgccaa gacttcatgg aagaagttag gcgtagagta tctcgaaaaa gcgcttgatc
     8281 tgactattcc caaagacagt aatatggtac ggctctatat tggcatgacc gactgctaca
     8341 aaatggcaca gatgcctaaa gagcagattg aatcgatcag agaacgctac cggaaatacg
     8401 ataaacaaaa tcataagctg ctctatgata tggctttcat ttatttctat tcgctgaaag
     8461 acaagaaaaa caccgaacgc tgtctggaag cattcttaaa aacacgcccg aaagaagata
     8521 aggaagaaga agcgaaacta aacgaacgag gcgaactcgt tttaggcact aagaattatt
     8581 ataatgctgc agctaactgg ctgaaagaca ttcaaagtaa gcaaaagata gaagatttct
     8641 tcttgggagg aaatgtgccc gctcagaaac cggaataagc agatagagaa tattacgtaa
     8701 aaaggctgca accgtcaaac gattgcagcc tttctatata ataggataat ctgtgattat
     8761 tcagccaatt tgttgtctga acccagcaca ttaaggattt tgtgcttgta cagtttttcc
     8821 atgttgtcac gagccggacc aagatactta cgtgggtcga attcagctgg tttttcagcg
     8881 aaagtcttac ggatagcagc agtcatagcc aaacgagagt ctgagtcgat gttgattttg
     8941 caaacagcag acttggcagc tttacgcaat tcttcttcag gaataccgat agcagctttc
     9001 agagcaccac caaacttgtt gattgtttca acttcttctt caggaactga agatgatccg
     9061 tgaagtacga tagggaatcc cggaagtttt tccattacag catccaatac ttcgaaagcc
     9121 aatggaggag gaaccatacg accggtagcc ggatcgatgt ggcactgttc cggagtaaac
     9181 ttgtaagcac cgtgagaagt accgatagag atagccaatg agtcacaacc tgtacgagta
     9241 gcgaaatcga ttacttcttc agggtcagtg tatgtgtggt ggtcagaaga aacttcatct
     9301 tctacacctg ccaatacacc aagttcacct tcaactgtta cgtcgaactg atgagcgtat
     9361 tcaaccacct tcttagtcaa agcaacgttt tcttcgtaag gaagatgaga accgtcgatc
     9421 ataactgaag agaaacctga atcgatgcaa gatttgcaag tttcaaaagt atctccgtgg
     9481 tcaaggtgaa gaacgatttc aggatgtgcg caacctaatt cttttgcgta ctctacagca
     9541 ccctgagcca tgtaacgcaa caaagtagcg ttagcatact gacgagcacc tttagaaacc
     9601 tgaagaatca ccggagattt tgtttctact gcagccttga tgatagcctg catctgttcc
     9661 atattgttga agttgaatgc tgggatagcg tatccaccct taatagcctt agcaaacatg
     9721 tctcttgtgt ttaccaatcc taagtctttg taattaacca ttttgtttaa agtttattgt
     9781 tagtgaatta aaattctacg caaaagtaag cattatccac cgaataacga gcatcggaaa
     9841 gaaaaatata atagaaaaag gtttaaatcg atcagcaaat attcatccgt aagcgggtct
//
