LOCUS       c00110_gnlPro..        14174 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MFBLIHAM_110.
ACCESSION   c00110_gnlPro..
VERSION     c00110_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 09:02:25
            Original ID  :: gnl|Prokka|MFBLIHAM_110
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14174
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..249)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg110_1"
                     /sec_met_domain="Rnf-Nqr (E-value: 7e-31, bitscore: 97.7,
                     seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNMKVLMNGIIKENPTFVLLLGMCPTLGTTSSALNGMSMGLATM
                     FVLICSNMVISALKNLIPDMVRIPAFIVVIATFVTVVQ"
     protocluster    1..14174
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:4174]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1..4174
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..14174
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14174
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             complement(242..847)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg110_2"
                     /sec_met_domain="FMN_bind (E-value: 3.9e-25, bitscore:
                     78.5, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLSLTIICLVAGAILAGVNMYTTGPIAASKAAALEAAIKAVTPE
                     FDNKPSEDAYMAVTGDGDSLKIYPATKGGEFVGAAVESNTKKGFSGEIKVIVGFDKEGK
                     LLNYSVLQHAETPGLGAKMQEWFSTDKNKQSVLGRSLSAGPLKVTKDGGNVDAITAATI
                     TSRAFLDAVNRAYSAFAGTDGVTGATTANTNEGGNDNE"
     CDS             complement(880..1839)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg110_3"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 9.3e-120,
                     bitscore: 389.4, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENNLIVSPSPHIHGGDSISKNMYGVLIALVPAFLVSLYYFGLGA
                     LIVTATSVIACVLFEYLIQKFLMKKEPTVCDGSAILTGVLLAFNLPSNLPVWIILIGAL
                     AAIGIGKMSFGGLGNNIFNPALVGRVFLLISFPAQMTMWPEVGQLTAYTDATTGATVLS
                     LMNEGALDKLPTLVDMLLGKMGGSLGEVSALALLLGLVFILWKKIITWQIPVSILLTVF
                     VFTGIMHLVNPVQYASPFVHLLSGGLMLGAIFMATDYVTSPMSKNGMLVYGVGIGILTT
                     VIRLFGSYPEGMSFAILIMNAFTPLINSYIKPKHFGGK"
     CDS             complement(1852..3183)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg110_4"
                     /sec_met_domain="Fer4_10 (E-value: 2.6e-10, bitscore: 30.5,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 2.2e-17, bitscore: 52.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 7.2e-51, bitscore:
                     162.2, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 3.5e-32, bitscore: 100.6,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.5e-05, bitscore: 15.6,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRTFRIGGIHPPENKLSAGKKITGLAIPKQVIIPLSQHIGAPAQ
                     AVVKKGDTVKVGTLLAKAGGFVSANIHSSVSGKVNKIDNALDTSGYKRPAIYIDVEGDE
                     WEESIDRSETLVKECPLPSKEIVDKIAAAGIVGLGGATFPTQVKLMPPPGSKAEIIIIN
                     AVECEPYLTSDHSLMMEKAEQILVGVTLLMKAVNVTKAVIGIENNKPDAIAHLSKLATA
                     YKGIEIMPLKVQYPQGGEKQLIDAVIRRQVKSGALPISAGAVVQNVGTAFAVYEAVMKN
                     KPLFERVVTVTGKAVTNPSNFLVRMGTPISALIEAAGGVPENTGKIIGGGPMMGKALIA
                     PEVPVTKGSSGVLLLTKEESVRKPMRDCIRCAKCVSVCPMGLNPTLLMNATEFAEWDLA
                     EKNYITDCIECGSCSYTCPANRPLLDYIRSGKGKVMGIIRARKS"
     CDS             complement(3188..4174)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 39; E-value:
                     3e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg110_5"
                     /sec_met_domain="Fer4_7 (E-value: 7.9e-13, bitscore: 39.0,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.1e-11, bitscore: 34.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 1.4e-09, bitscore: 27.8,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 1.1e-10, bitscore: 31.2,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.3e-06, bitscore: 18.9,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILIAVISLGAIGAIGAVFLYAASKKFEVYEDPRIAEVQEALPGA
                     NCGGCGYPGCGGFAAACVKADSLEGLLCPVGGAETMGKVASILGMEAATAEPMVAVVRC
                     NGTCQARPRTNQYDGVKSCAIASSLYGGETNCTFGCLGYGDCESACTFDAIHVNLTTGL
                     PEVDEDKCTSCGACVKACPKNIIELRKKGPKSRRIFVSCVNKDKGAAARKACANACIGC
                     GKCVKECPFEAITLENNVAYIDYRKCRLCRKCVAVCPTGAIHELNFPPRKEASPAVDAD
                     KVKPVTPKAAPALKAEAPTKVEVTPATAPETXXXXNNKRRNNSKIKI"
     CDS             complement(4184..4603)
                     /locus_tag="ctg110_6"
                     /transl_table=11
                     /translation="MSESINHNGIIEKIDGNAVFVRIIQQSACSGCHAQSMCSASEKKE
                     KIIEVNDNNPGRFHVNEEVTLCGQSSLGLQAVFLAFVLPLIVVVAAIVAGSCLQWDETT
                     SGLTGLLLLVPYYSILYFLREKLKRKFIFTLKKLN"
     CDS             complement(4705..6243)
                     /locus_tag="ctg110_7"
                     /transl_table=11
                     /translation="MVIKRYFILFSILSLLTNLANAQEVTTITGTNLKDTVQSNAADTI
                     PMIEIEDLDLDNIISLRAQFEKQNQSYSAPVTPNENLLRFLKKDEVELSDEAMYWARLV
                     RDASTIFDANMTFQDTVIADPLFLPLIFKGKLLPKDLSFYDEDAWKNKIDIPQPFLQDT
                     IFKEEVFRQQFREKAQRNIEANHPEYFRYSMRDLPQDKVVAKVIRKPTYQPDLIKVESE
                     ADFSDVDAPVKFIPERRYWTSHFESSLQFAQNYISPNWHKGGVSTLNLTNRELFTYNYN
                     KEKIKFDNSLEIKNNLYTAPKDTLRDYKVGDDVFRIYSNFGYKAFNKWYYTLDLDFKTQ
                     LFSSYAENQNVKLAGLLSPFSINFGLGMKYDLDKTFASSKHKKVTLSANLAPLSYTYVR
                     TLDKDIDLGRHFQKRDGEEEFPYKQSLFGSTVNATMTFQFSRNIIWYSRFYYMTDYKRI
                     QGEFENRLNMAISRFFSTIISLNLRYDDGISKHEDFDSYLQINELLSFGFNYKW"
     CDS             6472..8076
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg110_8"
                     /sec_met_domain="GATase (E-value: 2.4e-55, bitscore: 177.3,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VADTKYIFVTGGVVSSLGKGIIAASLGKLLQARGYKVTIQKFDPY
                     INIDPGTLNPYEHGECYVTVDGHEADLDLGHYERFLNVPTTRSNNITTGRIYQSVINKE
                     RKGDYLGKTVQVVPHITDEIKRNVKLLGSKYKFDFVITEIGGTVGDIESLPFIESVRQL
                     KWELGKNCMCVHLTYVPYIAAAKEFKTKPTQHSVKQLQELGIQPDVLVLRTEHLLSNDI
                     TRKVALFCNVDADAVVQSVDVPTIYEVPLVLQRQNMDVTILKKMGLEVGPTPEMKPWKE
                     FLKKKTDATETVKIGLVGKYVELQDAYKSIDESLLQAAIYNDRKLDLHLFHSEKLTEAN
                     AAEQLKDMDGILIAPGFGQRGIEGKFAALKYARENDVPCLGICLGMQCMVIEFARDVLG
                     MTDANSTEMEPNTPFKVIDLMEEQKNITNMGGSMRLGAYDCILKKGSKAYEAYGKEHIQ
                     ERHRHRFEFNSQYREQFEEAGMKCAGENPETGLVEVVEIPALKWFVGVQFHPEYNSTVV
                     NPNPLFVSFVKAAIDNK"
     CDS             8088..9908
                     /locus_tag="ctg110_9"
                     /transl_table=11
                     /translation="MDKNTLIGFLLIGIVLFAFSWFNKPTPEQLEAQRRYQDSIAQIEL
                     AKQAELQREDSKSTADNSFDSLPDSARDARLKSSFGVFAEAMTGTDDVTVLENDLIELH
                     ISNKGGRISYARLKDYTTYDDKPVILFEGKEASLDFTLVTATNRVLNTADLYFTPVKTQ
                     DPNRLVMRLNTGEGSSLDFIYTVKPDDYMVQFDIKGTGLNGVLAPSTTALDMVWRQKIR
                     QQEQGIKYENRYTALYYKFLSDDVEQLSESKSEDKKVSGRLKWIAYKDKFFSTVMIADE
                     GFESATFDSKMVEADGIVKEFKTTTXXXXXXXXXXXXXXXXXXXXXGASVFRWVNQYFV
                     IPMFDFLGKYIKSYGLIILLMTIIVKLILFPLTYKSYMSSAKMRVLRPQVEELNAKYPG
                     QDKAVERQRATMELYSRAGASPMAGCIPMLLQMPILIALFMFFPSAIELRHQSFLWAHD
                     LSTYDAIFSWNKYIPIITPYFGNHISLFCLLMTITNVIYTKYNMEMTNTGQQQMPGMKA
                     MMYMMPLMFLVFFNQYASGLTYYYFISTLITIVQTLVFRYTINEDKLLAKLEANKKKPQ
                     KKSGFMKRLEEAQRMQQEQLKKQQDQKKKR"
     CDS             10190..10972
                     /locus_tag="ctg110_10"
                     /transl_table=11
                     /translation="MDKKEKLLQKRVAGLFALLCVIFFXXXXEVLVGYWGKPAWLACSM
                     AKVLTSLFVPVGGGAVLITAVLMLEWWASLFILRKFNVGDMAPLYALFPVVMEWGTYCS
                     PYYHLNSILSLVIVLYIFCGYIQIKVKWLSWVTGFILLFAVYCMVGSRLFIFVILVLLY
                     EAEIGEKHWVYWALLLITGTVLPEFLKELYSLSEEQAYQYPQAWLPAFFPAIMLACVLV
                     ATQFKKVRYMQISVWSVSVTSGLLLVLLALTAFSHAVG"
     CDS             complement(10953..11249)
                     /locus_tag="ctg110_11"
                     /transl_table=11
                     /translation="MYFSRSIIPYMRGKNYQEWLPNHTYYKHIGLYAYRADTLKEITHL
                     PQSPLELAESLEQLRWLENGYKIKVGITQQETIGIDTPEDMEKALAFLSQQHG"
     CDS             complement(11257..11718)
                     /locus_tag="ctg110_12"
                     /transl_table=11
                     /translation="MKFIGIIPARYASTRFPGKPLADMAGRPMIQRVYEQVKDVLDTVC
                     VATDDSRIEAAVKAFGGNVVMTSDQHRSGTDRVYEAYTKVGQGYDVVVNIQGDEPFIHP
                     EQIETLKACFTDVGTQIATLVKPFRPDDDFETTLFNANSPKVVLXXXXE"
     CDS             complement(11747..13249)
                     /locus_tag="ctg110_13"
                     /transl_table=11
                     /translation="MIATKAGFSSALGAFVMGSILAETIDAEHIEHIVKPVKDLFGAIF
                     FVSVGMLIDPVLLWEYKIPILILTLVVMVGQILFATFGVLLSGQTVKVAIQSGFSLAQI
                     GEFAFIIASLGXXXXFTPYMIRMAEPAYKIAERVIPASWMSFLERYSSGSNTIRQKSAW
                     DKLLKALVRIVGTYTAVTLVLIFIWLQFVAPFMINQLPGLQGQIISLVLILLLISPMLR
                     AIMMKKNHSVEYQQLWHDSKYNRGPLVSLIVLRIILCIGLVMLPIARLLNTAVGIGLAI
                     AATVIALVIFSKRLKKQSILMERHFFTNLTARELENERNAPINQRFASHLLERDLHLAD
                     FEVKQNSPSMGKTLKELNFRQKCNVNIVTIIRGSKRINIPGGNERLYPFDKLVVVGADD
                     DLAHFRQYIEERYKESLNNLQETKEVNMEQFFISEGSGLIGRTILESGIRDNSGCLVIG
                     IERDARSIKNPPPTTVFEQGDIVWIVGEHEKVLRLSEGKTVK"
     CDS             complement(13246..13965)
                     /locus_tag="ctg110_14"
                     /transl_table=11
                     /translation="MSQIPSLISDLAVILISAGLVTLLFKKLKQPVVLGYIVAGILAGP
                     AIKEIPTVTDVESIRIWADIGVVFLLFALGLDFSFKKLMKVGGTAVIGAVTVVIGMMTF
                     GYITGLSLGWGHMNSLFLGGMLSMSSTTIIFKAFDDMGLRNQRFAGVVFGILVVEDLFA
                     VLLMVLLSTLAVSKHVEGMELLDSVIKLGVFLLFCFVVGIYLIPSFLKRARTFLNDETL
                     LIVSIGXXXXAYAWGWS"
ORIGIN
        1 ctgcacgacg gttacgaatg ttgcgattac gacaataaag gccggaatac gtaccatgtc
       61 ggggatcagg ttcttcaagg ctgaaataac catattggaa cagatcagaa cgaacatggt
      121 tgccagtccc atactcatac cgttcaatgc tgaagaagtt gttcccagag ttggacacat
      181 acccagcaac aagacaaatg tcgggttctc tttgatgata ccgttcatca atactttcat
      241 attactcatt gtcgtttcct ccctcgttag tgttagcggt tgttgcaccg gttactccgt
      301 cagttccggc gaatgcgctg taagcacggt tcaccgcatc cagaaatgca cggctggtga
      361 tggttgctgc tgtgatagca tccacgttgc caccgtcttt agttactttt aatggtccgg
      421 cggacaggct gcgtcccaaa acgctttgtt tattcttgtc cgtactgaac cattcctgca
      481 ttttagctcc cagaccggga gtttccgcat gctgtaatac ggaatagttc aataacttgc
      541 cttccttatc gaatccgacg atcactttga tctctccgct gaatcctttt tttgtattac
      601 tttcgacagc tgcacctacg aactctccgc ctttggtagc cggatagatt ttcagggaat
      661 cgccgtcgcc tgtaactgcc atataagcgt cctctgacgg tttgttgtcg aattcaggtg
      721 taacagcttt gatagcagct tccagcgcag cagctttgga ggctgcaatc gggccggtag
      781 tgtacatatt tactccggct aatatcgctc ccgcaaccaa acagatgatg gtaagcgaca
      841 agagcatatt gggtaatgtt gattttagtt ttgccatgct tatttccctc caaaatgttt
      901 aggtttgata taactgttga tcagcggggt aaatgcattc ataataagaa tagcaaacga
      961 cataccttcc ggataagaac caaacagacg gataacggtg gtcagaatac cgataccgac
     1021 accgtaaacc agcataccgt tcttactcat gggcgaagtc acatagtcgg ttgccataaa
     1081 gatggctccc agcatcagac ctcccgacag caggtgaacg aacggacttg cgtattgtac
     1141 cggattaacc aggtgcataa tacctgtgaa tacaaatacg gtcagcagga tagaaaccgg
     1201 aatctgccag gtaataatct ttttccataa tataaagacg agtcccagca gcaatgccag
     1261 tgcacttact tcaccaaggc tgccgcccat tttacctaac aacatatcta ccagggtagg
     1321 caacttgtcg agtgcccctt cgttcatcag tgataaaaca gttgcaccgg tggttgcgtc
     1381 ggtgtaggct gtcagctgtc cgacttccgg ccacatcgtc atctgtgccg ggaaagagat
     1441 cagcaggaat acacgtccga ctaatgccgg gttaaaaata ttgttaccca gtccgccgaa
     1501 cgacatctta ccgataccga ttgctgccag tgcaccgatc aggatgatcc atacaggcag
     1561 gttcgacggc aggttgaatg ccagcagtac accggtcagg atagccgaac cgtcacatac
     1621 ggtcggttcc tttttcatca ggaacttctg gatcagatat tcaaagagga cgcaggctat
     1681 gaccgatgtt gcagtaacga tcagcgcacc cagcccgaag tagtagaggg ataccaggaa
     1741 agccggaaca agggcaatca gtacaccata catatttttg cttatgctat cgccgccgtg
     1801 gatatggggc gaaggagata ctattaaatt attttccata ttgctctgtt tttatgactt
     1861 tcgtgcccgt atgataccca ttacctttcc tttacccgaa cggatataat ccagcaacgg
     1921 acggttggcc gggcaggtat aactacaaga accgcactcg atacagtcgg tgatataatt
     1981 cttctcggcc aaatcccatt ctgcaaattc tgttgcattc atcagcaggg tagggttgag
     2041 gcccatcgga caaacgctga cacatttggc acagcggata cagtcgcgca tcggtttgcg
     2101 gacagactct tcttttgtca ggagcaatac gcctgaacta cctttcgtta ccggtacttc
     2161 cggagcaatc agggcttttc ccatcatcgg gccgccaccg attatctttc ctgtattttc
     2221 aggaacacca ccggcagctt caatcagtgc actgataggc gtacccatac ggaccaggaa
     2281 gttggaagga ttggtaactg ctttacctgt cacggtaacg acgcgttcaa acaaaggttt
     2341 gtttttcatt accgcttcat acactgcaaa agcagttcct acattttgta ctacagctcc
     2401 ggcggaaata ggcagtgcac cgctcttcac ctgacggcga atcacagcgt cgattaattg
     2461 cttttcacct ccttgcggat actgtacttt cagcggcata atctcgatac ctttataggc
     2521 tgtagccagt ttactcagat gagcgatggc gtcaggcttg ttgttttcga taccgatcac
     2581 tgcttttgtt acatttacag ctttcatcaa cagcgtaacg ccgaccagaa tctgctctgc
     2641 cttctccatc atcaatgaat ggtcggaagt cagatacggc tcacattcta cggcattgat
     2701 aatgatgatc tcggctttgc ttccgggagg cggcatcagt ttgacctgtg tggggaatgt
     2761 cgcaccaccc agacccacga taccggctgc ggcgatcttg tctacgatct ctttggaagg
     2821 aagcgggcac tctttcacga gcgtttcgct gcggtcgatc gactcttccc attcgtcacc
     2881 ttccacatca atatagatag cgggacgttt gtatccgctt gtgtcgagag cgttatctat
     2941 cttgtttact ttaccggata ccgacgagtg gatattcgcc gatacaaaac ctccggcttt
     3001 ggcgagaagc gtacctactt taaccgtatc acccttcttt accacagcct gggcaggagc
     3061 cccgatatgc tggcttagcg gtataataac ctgcttgggt atagccagtc cggttatttt
     3121 cttcccggca gacaatttat tttcgggtgg atgtatacct ccgattcgaa atgtccttag
     3181 catactatta gatttttatt tttgagttgt ttcttctttt gttattgtnn nnnnnnnntg
     3241 tttcaggcgc tgttgccggt gtaacttcga cttttgtcgg tgcttcggct ttaagggccg
     3301 gtgcagcttt aggcgttact ggctttactt tgtcggcgtc cacagcaggg gaggcttctt
     3361 tacggggcgg aaagttcaat tcgtgaattg ctccggtcgg acatactgct acgcatttac
     3421 ggcacagacg gcatttgcgg tagtcgatat aagccacgtt gttttcgagc gtgattgctt
     3481 cgaacggaca ttctttcaca catttaccac aaccgataca agcgttcgca catgctttac
     3541 gggcagcagc tcctttgtct ttgtttacgc agctgacgaa gatacggcgt gatttcggtc
     3601 cctttttgcg cagttcgata atgtttttcg gacaagcttt gacgcaggct ccgcatgaag
     3661 tacatttgtc ctcgtccact tccggcagtc cggttgtcag attgacgtgg atggcgtcga
     3721 aggtacaggc actttcgcag tcgccgtaac ccaggcaacc gaacgtacag ttcgtttcgc
     3781 ctccgtacaa agaggatgct atggcacagc tttttacgcc atcatactgg ttggtgcgcg
     3841 gacgggcctg gcaggttccg ttgcaacgga caactgctac cattggttcg gctgtagcag
     3901 cttccatacc gaggatggat gcgaccttac ccattgtttc ggcgccaccg accggacaaa
     3961 gcagtccttc cagtgaatcg gcctttacac aggctgctgc aaaaccaccg caaccggggt
     4021 aaccgcaacc tccgcagttg gctccgggca atgcctcctg gacctctgcg atacgaggat
     4081 cttcgtatac ttcaaacttc ttggaggcgg cgtagaggaa tactgcgccg atggctccaa
     4141 tggctcctaa tgaaataacg gcaattaaaa tcatgatatt tgatcaatta agttttttca
     4201 aggtaaatat aaattttctt ttcagtttct cgcgtaaaaa gtataatata ctgtagtagg
     4261 gaactagtag taatagaccg gttaacccgc tggttgtttc gtcccattgc aaacagcttc
     4321 ctgctacaat cgccgcaact acaacaatca gaggaagcac aaaggccaga aaaaccgctt
     4381 gcaggccgag cgaactctgg ccacataggg ttacttcttc gttcacatgg aatctgccgg
     4441 ggttattgtc gttcacttca atgatctttt ccttcttttc agatgcgctg cacatgcttt
     4501 gtgcgtggca accggagcag gccgattgtt gaatgattct gacaaagacc gcattgccat
     4561 cgatcttctc tattattccg ttgtgattga tactttcact catgtttgta atctcgacat
     4621 tgcaaaatca ggggcaaaag taaggattat ttggatatta tgtcacgatt aacaaagttt
     4681 attacagaaa taatcgtgtt cagcttacca tttgtaatta aagccaaagc tcaacaactc
     4741 gttaatctgt aagtagctgt cgaagtcttc atgcttggag ataccatcat cataacgtaa
     4801 gttcagcgag atgatagtcg agaagaatcg acttattgcc atattcagac ggttttcgaa
     4861 ctcaccttgg atacgcttat aatctgtcat gtaatagaaa cgcgaatacc agatgatatt
     4921 ccggctgaac tggaatgtca tagttgcgtt gacggtagaa ccgaacaggc tttgtttgta
     4981 aggaaactct tcttctccgt ctctcttctg gaaatgccgg cccaggtcga tgtctttatc
     5041 taatgtacga acgtacgtat aagataacgg tgcaaggttg gcacttaacg ttactttttt
     5101 gtgtttggac gacgcgaacg ttttatccag gtcatatttc ataccaagac cgaaattaat
     5161 actgaaaggt gagagcagtc cggccagttt aacgttctgg ttttcggcat aactgctgaa
     5221 aagctgggtt ttgaagtcaa gatccagtgt gtagtaccat ttgttgaatg ccttataacc
     5281 aaagttactg tagatacgga acacgtcatc tccgactttg taatcgcgca aagtatcttt
     5341 gggagcggta tacaggttgt tctttatttc cagtgaattg tcgaacttta tcttttcctt
     5401 attataatta tatgtaaaca gttcgcggtt ggtcaggttc agcgtactta cacccccttt
     5461 atgccagttc ggagagatgt aattctgagc aaactgtaaa gaactttcga aatgtgacgt
     5521 ccagtaacgt ctttcgggaa tgaattttac cggtgcatcc acgtcactga agtctgcttc
     5581 gctttctacc ttgatcaggt ccggttggta ggtcggcttt ctgatcactt tggcaactac
     5641 tttgtcctga ggtagatccc tcattgaata acggaaatat tcaggatggt tggcttctat
     5701 atttctttgt gctttctcgc ggaactgctg tctgaacacc tcttctttaa atatggtgtc
     5761 ctgaagaaaa ggttgcggga tatcgatttt atttttccat gcatcttcat cgtagaagga
     5821 aagatctttc ggaaggagtt tccctttgaa tatgagcggt aaaaacagcg ggtctgctat
     5881 gactgtatcc tgaaatgtca tattcgcgtc gaagatagtg gaagcatcgc gcaccagacg
     5941 tgcccagtac atggcttcgt ccgacagttc cacttcgtct tttttcagga agcgaagcag
     6001 attttcattc ggtgtgaccg gtgctgaata tgactggttt tgtttctcga attgtgcccg
     6061 caggcttatg atattatcca ggtccagatc ttcgatttca atcattggga tagtatcagc
     6121 cgcattactc tgtactgtat ctttaagatt ggttccggta atagttgtca cttcctgtgc
     6181 atttgccagg tttgtcaata atgaaagtat agaaaataga atgaagtatc tcttgataac
     6241 cataattcct ttttatttac aatctataag tatctacggt gcgaaattag ataaaaagta
     6301 tgaaatctac taatctttca catcatataa caatctgaac taatagggaa accggaatgc
     6361 ggatgaatgt gctttgaaaa aatatccgag acacttgctg tctgaatgaa aatgannnnn
     6421 nnnnntttga aatgcgagtg agcaattaaa gacaattaaa atattactat cgtggcagat
     6481 acaaagtaca tcttcgttac gggcggcgta gtctcttctt taggtaaggg aattattgct
     6541 gcatcattgg gtaaactcct tcaggcgaga ggttacaagg ttactatcca aaagtttgac
     6601 ccctacatta atatcgatcc gggtacattg aacccttatg agcacggtga atgttatgta
     6661 accgtagacg gacatgaagc ggacctggac ctgggacatt atgaacgttt cctgaatgtt
     6721 ccgactacac gctcgaacaa tattacgaca ggtcgtattt atcagagtgt gataaataag
     6781 gaacgcaagg gcgattatct gggcaagact gtgcaggttg ttcctcatat caccgacgag
     6841 atcaagagaa atgtgaagct gctgggatcg aagtacaagt ttgactttgt gatcacggaa
     6901 atcggtggaa cagtaggcga tatcgaatcg ctgcctttca tcgaaagcgt tcgccagctg
     6961 aaatgggaac tgggtaagaa ctgtatgtgc gtacatctta cttatgtacc ttatatcgca
     7021 gctgcgaaag aatttaaaac gaaacctaca cagcattctg taaaacagtt gcaggaactg
     7081 ggtatccagc cggatgtact ggtcttgaga actgaacatt tgctgagtaa tgatattacc
     7141 cgcaaggttg ctttgttctg taacgtagac gccgacgctg tagtgcagtc ggtcgacgtt
     7201 cctactattt atgaagttcc gctggtattg cagcgtcaga acatggatgt aactatcctg
     7261 aaaaagatgg gattggaagt agggccgact ccggaaatga aaccctggaa agagttcctg
     7321 aagaaaaaga cggatgctac cgaaacagtt aagatcggtc tggttggtaa atatgtggaa
     7381 ttacaggatg cttataagtc aatcgacgaa tcattgttgc aggctgctat ctacaacgac
     7441 cgcaaactgg atcttcattt gttccattcg gaaaaactga ctgaagccaa tgcggctgaa
     7501 cagttgaagg acatggatgg tatcctgatt gctccgggat tcggacagcg cggtatcgaa
     7561 ggaaagttcg ctgccttgaa atatgcccgc gaaaacgatg tgccttgcct gggtatctgc
     7621 ctgggtatgc aatgtatggt gattgaattt gcccgcgacg ttttgggtat gacggatgcc
     7681 aattcgaccg agatggagcc gaatacgccg tttaaggtga tcgacctgat ggaagaacag
     7741 aagaacatta ccaatatggg aggttctatg cgtctgggag cttacgactg tatcctgaag
     7801 aaaggttcca aagcctatga ggcttatgga aaagaacata tccaggaacg tcaccgtcac
     7861 cgtttcgaat tcaacagcca gtatcgcgaa cagtttgaag aagccggcat gaaatgtgca
     7921 ggcgagaatc cggaaaccgg tctggtggaa gtggtagaaa ttcctgcgtt gaaatggttc
     7981 gttggtgttc agttccatcc ggaatacaac agtacggtag ttaatccgaa cccacttttc
     8041 gtgagctttg tgaaagccgc tattgataat aaataacaac gttatagatg gataaaaaca
     8101 cattaattgg ttttctgctt attggtattg ttttatttgc attcagctgg tttaacaaac
     8161 cgacgcctga gcagttggaa gcccagcgcc gttatcagga ctcgatcgct cagatcgaac
     8221 tggctaaaca ggcggagttg caacgcgaag acagcaaaag cactgccgat aattcttttg
     8281 atagcttgcc ggattctgcg agagatgccc ggctgaagag cagtttcggt gtattcgctg
     8341 aagcaatgac aggtacagat gatgtaactg ttttggaaaa tgatctgatc gaactgcata
     8401 tcagtaataa gggaggacgt atttcatatg cccgcctgaa ggattataca acatatgatg
     8461 ataagccggt catcctgttt gaaggaaaag aggcttcgct tgactttacc ctggtaacag
     8521 caaccaaccg cgtattgaac acagccgacc tgtatttcac tccggtgaaa acacaggacc
     8581 cgaaccggtt ggtgatgcga ctgaatacag gtgaaggcag ttcactggac tttatctata
     8641 cagtcaagcc ggacgattat atggttcagt tcgatattaa gggaacgggc ctgaacggtg
     8701 tcctggctcc gagtacgact gctttggata tggtatggcg tcagaaaatc cgccagcagg
     8761 aacagggtat caaatatgaa aacagatata ctgccttgta ttataaattc ctgtccgatg
     8821 atgtggagca gctgagcgaa agcaagagcg aagacaagaa ggtgtcgggc cgtctgaaat
     8881 ggattgctta taaagataaa ttcttctcga cggtgatgat tgccgatgaa ggttttgaaa
     8941 gcgctacttt cgattcaaag atggttgagg cagacggtat cgttaaagag tttaagacta
     9001 caacannnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     9061 nnnnnnnngg tgccagtgtc ttccgttggg tgaaccagta tttcgtcatt ccgatgtttg
     9121 acttcctggg taaatatatc aagagttacg gtctgatcat cctgttgatg acgattatcg
     9181 tgaaactgat tttattcccg ttgacatata aatcatatat gtcgtcagcg aagatgcgtg
     9241 tgcttcgtcc gcaggtggaa gagcttaatg ccaaatatcc gggacaggat aaagcggtgg
     9301 aacgccagcg tgcaactatg gaattgtata gccgagccgg ggcaagcccg atggcaggtt
     9361 gtatcccgat gctgttgcag atgccgattt tgatcgcctt gttcatgttc ttcccgtcgg
     9421 caatcgaact gcgtcaccag agtttccttt gggcgcacga tttgtcaaca tacgatgcta
     9481 ttttcagttg gaacaaatac attcctatta tcactccgta ttttggtaac cacatcagtt
     9541 tgttctgtct gctgatgaca atcaccaacg ttatctatac caagtataat atggaaatga
     9601 ccaataccgg acagcaacag atgccgggta tgaaggcgat gatgtatatg atgccgctga
     9661 tgttcctggt attcttcaac cagtatgcat cgggtctgac ttactattac ttcatttcta
     9721 cgctgatcac gattgttcag acattggtgt tccgttatac gattaatgaa gataagctgc
     9781 tggctaagct ggaagccaac aagaagaagc ctcagaagaa atcaggtttc atgaaacgtc
     9841 tggaagaagc gcagcgtatg cagcaggagc agttgaagaa acaacaggat cagaaaaaga
     9901 aaagataaca gctttttctg caagataaat aaaagagagg cgtgccggtc cggaaaagac
     9961 tcaggcacgc ctttttttgt gtccggatta tgcaataagt tgtatatttt gtacaatcgc
    10021 ttgaatttga agaaatgtgg tgtgcgttgt attaaaatat ttatatattt gcactattga
    10081 tatataagtc aactattgat gattatgctt acgttgacga cttatccggt cggaatagca
    10141 agtaccggct ttacgttttg agtttaatag gtataaaaat agttcactga tggataagaa
    10201 agaaaagctt ttgcaaaaga gggtagctgg actctttgca ttgctatgcg ttatcttttt
    10261 ccnnnnnnnn nnggaagtgt tggtcggcta ttgggggaaa cctgcatggc tggcttgttc
    10321 aatggcgaaa gtacttacgt ctttgtttgt tcctgtcggt ggcggggctg ttttgattac
    10381 ggccgtgttg atgctggaat ggtgggcttc tttatttatt ctgcggaaat tcaatgtagg
    10441 ggatatggct cctttgtatg ctctgtttcc ggttgttatg gagtggggaa cctattgtag
    10501 tccttattat catttgaatt ctattctttc tttggttatt gttttgtata tattttgtgg
    10561 ttatatacag ataaaggtaa aatggctctc ttgggtgacg gggtttattt tgttgtttgc
    10621 ggtttattgt atggtgggga gccggttgtt tatttttgta atccttgtgc tgttgtacga
    10681 ggcggaaata ggagagaagc attgggtgta ttgggctttg ctgttgataa cgggtactgt
    10741 gctgcctgaa ttcctgaaag aactgtactc actttcagaa gaacaggcat atcaatatcc
    10801 acaggcatgg cttccggcat ttttcccggc tatcatgctg gcttgtgtgt tggtggctac
    10861 gcagtttaag aaagtccggt atatgcagat cagtgtatgg tctgtatctg tcacttccgg
    10921 acttttactg gtattgctgg cgcttactgc gttcagccat gctgttggct gagaaaagca
    10981 agtgctttct ccatgtcttc aggcgtgtcg ataccgattg tctcctgctg ggtgatgccg
    11041 acttttatct tgtagccgtt ttcgagccat ctgagttgtt ccaggctttc ggcaagctcc
    11101 agtggtgatt ggggcaggtg ggtgatttct ttcagcgtat cggcccggta agcatacaaa
    11161 ccgatatgtt tgtaatacgt atggttgggt aaccattcct ggtaattttt gccgcgcata
    11221 taaggaatga tggaacggct gaaatacatt gcttcgttat tcnnnnnnnn nnttgagaac
    11281 tactttcggt gagtttgcat tgaataatgt cgtttcgaag tcatcgtccg gacggaatgg
    11341 ttttaccagt gtggcaatct gcgtgccgac atcagtaaaa catgctttta acgtctcgat
    11401 ctgttccgga tggatgaaag gttcgtctcc ctggatattg acaacgacat cgtatccttg
    11461 tccaacttta gtgtaggctt cgtaaacacg gtcggtgcca ctccggtgct ggtcggaagt
    11521 cataacgaca tttccgccga atgctttcac ggcagcttcg atacggctat cgtcggtggc
    11581 tacacaaacg gtatccagta catccttcac ttgttcatac acacgctgta tcatgggcct
    11641 gccggccatg tcggccaaag gtttccccgg gaagcgggtg gaggcatatc ttgccggtat
    11701 tattcctata aacttcatac tccggttgtt tttattcgtt agttaattat tttactgttt
    11761 taccctcact gagacgaagc actttctcat gttcgccgac gatccataca atatctccct
    11821 gctcgaatac ggttgttgga ggcgggtttt tgattgaacg ggcatctcgt tcgataccga
    11881 tcaccaggca gccggagtta tcgcgtattc cggattcaag gatagtccgg ccgataagtc
    11941 cggagccttc actgataaag aattgttcca tattcacctc tttagtctcc tggaggttat
    12001 tcagcgattc tttataacgc tcctctatgt attgacggaa atgggccagg tcgtcatccg
    12061 caccgactac gaccagctta tcaaacggat aaagccgttc gtttcctccc ggtatgttga
    12121 tacgcttgct tccccggata atagtaacga tgttcacatt acatttctgc ctgaaattaa
    12181 gttctttgag tgtcttgccc atactggggg agttttgctt cacttcaaaa tcagccaggt
    12241 gaaggtcgcg ttccagcaga tggctggcga accgttggtt gatgggagcg tttcgttcgt
    12301 tctccagttc acgtgccgtc aggtttgtga agaaatggcg ttccatcagg atcgactgct
    12361 tcttcaaccg cttagagaag ataaccaggg ctatgacggt ggctgcgatg gcgagcccta
    12421 ttccgacagc agtgttcagc aggcgtgcga tcggcagcat gacgagccct atacataata
    12481 taatacggag cacaatcagg gaaaccaacg gaccacggtt atatttgctg tcgtgccaca
    12541 attgttggta ttctacggaa tggttctttt tcatcatgat ggcacgcagc atcggtgaga
    12601 ttaggagaag gatcagaacc agggaaatga tttgtccttg cagtcccggt agctgattga
    12661 tcatgaacgg agcgacgaat tgcaaccaga taaagatcag taccagcgtg acagccgtat
    12721 aggtgccgac gatacgcacc aatgctttca gcagtttgtc ccaggcactt ttctgccgga
    12781 tcgtgttgga gccagaagaa taacgttcca gaaaactcat ccagcttgcc gggatgactc
    12841 gttcagctat tttataagcc ggttcggcca tacgtatcat atagggcgta aaannnnnnn
    12901 nnngtcccaa agaggcgatg ataaaggcga actcaccgat ttgtgccagc gagaaaccgg
    12961 actggatggc gactttgaca gtctgtcccg ataatagtac gccgaaggtg gcaaaaagta
    13021 tctgtccgac catgacgaca agtgtcagta tcaggatcgg tattttgtat tcccaaagta
    13081 ataccgggtc gatcagcatg ccgacagaaa cgaagaaaat ggctccgaac aagtctttta
    13141 ccggttttac gatatgttct atatgttccg catcgattgt ctcagcaagg atagacccca
    13201 tcacgaaagc gccaagtgca gaagaaaatc cggctttagt cgcgatcatg accatcccca
    13261 ggcataggcc nnnnnnnnnn ggccgatact gacgatcagc agggtttcgt cattgaggaa
    13321 agtccgtgct cttttcagga aagaaggaat aaggtaaata cctactacaa aacagaagag
    13381 caggaatacc cccagtttga tcacgctgtc gagcaactcc atcccttcga catgtttact
    13441 gacggcaagt gtggaaagca aaaccatcag caggacagca aataagtctt ccaccactaa
    13501 tatcccgaac accactccgg caaaccgttg gttgcgcagc cccatatcgt cgaaagcctt
    13561 gaatatgatt gtcgtggacg acatggaaag cattccgccc aggaaaagac tattcatgtg
    13621 cccccagccg agcgacaatc cggtgatata gccgaacgtc atcatcccga taacgacggt
    13681 gactgctccg ataacggcgg tgcctccgac tttcatcagt ttcttaaaac tgaagtccag
    13741 tcccagggca aaaagcagga atacgacacc gatgtcggcc cagatacgga tactttctac
    13801 gtctgtaacg gtagggattt ctttaatggc tggtcctgcc agaattccgg caacaatata
    13861 gccaagtacg accggttgct ttaatttctt gaaaagcaaa gtaacaagcc ccgcagaaat
    13921 cagtattact gccaggtctg aaattaatga agggatctgt gacatgcttt cactcttttt
    13981 cggttggcaa agttagacat ttattttaat tttgcaggtc aaataatgag ccaaaatgaa
    14041 gaagaaacat ccgatagaag cattgattga acagggcgag catcaacaac tcgattttaa
    14101 gttcgaagtg agcgacagta agaagattgc ccgcaccttg tctgcttttg ccaataccga
    14161 tggcggtcgg ttgc
//
