LOCUS       c00004_gnlPro..        18511 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KOCAPCJI_4.
ACCESSION   c00004_gnlPro..
VERSION     c00004_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 09:52:19
            Original ID  :: gnl|Prokka|KOCAPCJI_4
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 18511
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..18511
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[5447:8511]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      5448..8511
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     cand_cluster    1..18511
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /kind="single"
                     /product="Pyruvate2acetate-formate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..18511
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Pyruvate2acetate-formate"
                     /region_number="1"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /tool="gutsmash"
     CDS             127..1488
                     /locus_tag="ctg4_1"
                     /transl_table=11
                     /translation="MIHMTLRKKTLWFLGALSFFASLAAAFAVFWLNRNDSSPAEWNFN
                     PIWTKAEKEQILTAANFTAHRSPERFIYRGLSLNSRHIDWHMFSEVSMRQYMKDEIRER
                     LQMIRDTAESADGRCITPSHETLLHLAAGLGEVQLLNRLLQRHADPNVQIILPQQAFPS
                     IPDSEQGNTPLTYACQPGMDDSTPLPVHNRLSCLNLLIQYGADVNKPGPLGWPPLIITC
                     VAGIGGAPYEEAALFLLKCGADISLQPELKGKKTSLLTWAAAAGYPLLVRKLCEAGYDP
                     NFRGEMAPPLLSLNLNTPNAALQIAHILLEYGADVNAAMPASTTLPETAGDTALLNLCR
                     QLAFIDVSCLPQIRDLVNLFIKEGADVNHQNAAGETPLMACCRGMLLGDDSLDRLKLGI
                     ARLLLDHHANPSLKDKYGRTALQRIGNRSNEHLQMVLKYLPELSAPPLPKKENH"
     CDS             complement(1502..3289)
                     /locus_tag="ctg4_2"
                     /transl_table=11
                     /translation="MKNLLFALLTGSFCCCYAQQKAAPVPEPEVVATPPADAGRGLIRV
                     DSREIRHYSGTRKEPDYLVSRDNGKTWEMKAAPAGYPPNYGGIPKESPAIVRNPLTREF
                     IRVQPIGGFVFLSRGGLDGKWLAVTNDGKLEEDWKDPEKRKNLKKLGGIMRTPVFVNKG
                     RRVIVPFHNMGGGTKFHISDDGGLTWHVSRNGVTSPRHEARPPHQGVRWFNNAVEATVL
                     EMKDGTLWALARTSQDQAWQAFSKDYGETWSKPEPSRFFGTLTMNTLGRLDDGTIVSLW
                     TNTMALPENATAGNGTWEDVFTNRDSHHIAMSGDEGKTWYGFREIILDEHRNHPGYATL
                     DGPEDRGKHQSEMVQLDKNRILISLGQHKNHRRLVIVDRRWVGAKTRATQTGKDLDSQW
                     TIHTYIPQKKGHCSYNRKPSAELVQDPSGGTKKVLQIKRLDDPELVNEKSNVDYRNGGA
                     TWNFPNGTTGLVKFRFRVADGEQADDSGLQVSLTDRLFNACDSTTKDYALFTFPIRLRP
                     APHLLLGMKKVPFSPGAWHEISLLWQGGQAVVSLDGKKAGTLKMANKSPNGVSYIHFIS
                     TGSQPDAGILLDTVNARVK"
     CDS             complement(3374..4162)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_3"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 1.8e-22, bitscore:
                     74.7, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFLSYMLAILLGSSSLAFSAPSIPASALPATLKPEPHQRDPYDW
                     NARHEAVKKRNRAVKPEYVMIGDSITHHWGGEPSGDGKNTGSGSWEKLFGPHAATNMGF
                     GFDYVDNAYYRVQNGELDGISPRVIIVLLGTNNLGHRKDTPQACADNIRAFVRLVRRKC
                     PSSKILLLGVLPRKEKNLAEPVKQTNRLLAELHNGKDIFFADPGKALLSADGASPQNEF
                     MKDVVHPNARGYEVLEKELAVLLKKLDAKYRGGKQAGKHS"
     CDS             complement(4385..5167)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lipase_GDSL_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_4"
                     /sec_met_domain="Lipase_GDSL_2 (E-value: 1e-22, bitscore:
                     75.4, seeds: 1564, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSYACLCLLLAGVFCVACFSGACADELPPTLKPQVNPRAVYDWK
                     KRHEAVMERNRTVKPEYVVFGDSITHRWGGEPSGDNRALGTGKTAWHSLFSSHAVTNMG
                     FGSDYVDNAYYRLQLGELDGISPRVIIVLLGTNNLGGRKDAPRACADNLKAFVSLARRK
                     CPSSKILLLGILPREGKKLAPLIRETNKMISGLADGNSVFFANPGEEFLGEDGVSPKPG
                     LLEDGLHPSARGYDILGKSLSVLLKKMDDKYGKLPAPR"
     CDS             5448..7715
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_5"
                     /sec_met_domain="Gly_radical (E-value: 3.1e-44, bitscore:
                     144.0, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate2 (E-value: 1.3e-280, bitscore:
                     926.0, seeds: 33, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MISIVKDLKESTALPQEWQGFKPGTWTESIDVRDFIQHNYTPYSG
                     NEEFLSGPSQRTLRLWDELKVLLKREIDNGGVLDADEEVVSSITSHKPGYIDKELEVVV
                     GLQTDAPLKRALMPFGGLRMAQQALESYGFKMCEKTADIFKKIRKTHNEGVFDAYTSDI
                     RAARSAGIITGLPDAYGRGRIIGDYRRVALYGTDKLIAERRKDLKNREHSPLTDELIRL
                     REEMSEQIRALEELAQLGASYGCDLTRPAANAREAVQWTYLGYLAAVKEQNGAAMSLGR
                     VSTFFDIYFTRDLEQGLITEEEVQEIIDQFVMKLRIVRFIRTPDYNNLFSGDPTWVTES
                     IGGMGEDGRTLVTRSSFRMLQTLYNLGPAPEPNLTVLWSRNLPEAFKSFCAKVSIETSS
                     VQYENDDLMRPHWGDDYGIACCVSAMRIGKQMQFFGARANLAKCLLYALNGGVDELKGK
                     QVAPPSPRYTEEILNYDEVMALYDKMQDWLAKTYIDALNIIHYMHDKYCYERIEMALHD
                     PEILRTMATGIAGLSVAADSLSAIKYATVKAIRNEEGLIVDFKTEGEFPCYGNNDPRVD
                     DIACSLVSNFMEKLRRLHTYRNSLPTQSILTITSNVVYGKKTGNTPDGRRAGEPFAPGA
                     NPMHGRDRNGAVASMLSVAKLSYDDSLDGISYTFSIVPQALGKEERERRVKLVSLLDAY
                     FAATGHHINVNVLERKTLLDAMDHPEKYPQLTIRVSGYAVNFIKLTREQQQEVINRTFH
                     TR"
     CDS             7732..8511
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 53.7;
                     E-value: 9e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_6"
                     /sec_met_domain="Radical_SAM (E-value: 3.7e-30, bitscore:
                     99.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQVFPQNHDPDGESSVTGLVHSVESCGTVDGPGIRFVLFLSGCS
                     LRCRYCHNPDTSYVRRGRLRSADDVLKEIARYRDFLQAAGGGVTLSGGDPLFQPDFAGA
                     VLKGCRKLGLHTCLDTSGHLGVNAGEEMLADTDLVLLDIKAWNPKRYRALTGGELHPTL
                     EFAERLASLRKPVWLRYVLVPGVTDNLEEIEELSRHAALLGNVERVDVLPFHQLGRFKW
                     DELKLDYTLKDVPEASAELAEQVRGIFRQGGFPDCVH"
     CDS             complement(8760..10685)
                     /locus_tag="ctg4_7"
                     /transl_table=11
                     /translation="MTDSSSPDSSPASRNTFAHHLGMKGFLLMEGLLKLVGMKTLYRLG
                     RAAGAVAWHLLPQRRNIVERNLRIVLDPALRGKELQKLSRENFKRTIANFLCSAKTATL
                     TDEQLKHCVTVGGHEQFAAPVLEGRGQVCAIAHSGNWEALARIRAFYPEVERYGSMYRQ
                     FDNPLMEEYVYQRRTERGTQMFSKEGGIKAPMKMLKEGGALGVLSDQFVWEGVYVPFFG
                     KVTGTTPLPALLRKRAGADMVAIAVRTDAPGHWIADMGNVVDFSRSDGSLAGDTIEVNR
                     GLETLIRESVLDVFWMHHRWKSVDRFAPQDKKTAALLENMELKPYRILVAVPRALDEAL
                     ATVPLIRALKTVRCDMQVNIVCPSAQLGIWKTVPEVTHVLPHDSLKQLREALAADEFYN
                     DGPLDLGVMLDGDMETLKALEPYGPMMFSGLDTHPGARKYKFRVKAPVLRAAPPAHRVQ
                     LYLQLGGLHGLDAATPSLFPVKKAAPAEDAPILIAPFSRLGSASEWSWEQWRELVSLLP
                     GRTVLAALEEDRERAASLAEHLNVELAVGAPEALFPVMDGAAAAVAVDGDLPSLCSFRG
                     LPVVTLFSTRLPDVYRPMGTFNRSLYSHQCCSPCFRKECDRDVPCNRHIAVRDVLEALR
                     EISGKE"
     CDS             11000..11137
                     /locus_tag="ctg4_8"
                     /transl_table=11
                     /translation="MKRRHADCQIVKRKGTLYVICKSNPKFKARQGATAGTRLSKKGVK
                     "
     CDS             11224..12387
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_9"
                     /sec_met_domain="Abhydrolase_1 (E-value: 9.7e-29, bitscore:
                     94.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLPAVQTKFLDLPNSFSLRNGATLDKVRVAYEQYGTLTPNKDNA
                     ILLFHALSGSQHAYGYNPEVPGIGSLWKPENHEGWWNSIIGPGKPLDTNRFCIICANYL
                     GGCYGTTGPATPCPADGQPYGSRFPHVEAADQARLQALLLDSLGIERVHLMGPSVGGLI
                     ALSFACQFPERVRSFISIGSGYRASIEHRLSLFEQILAIELDPDFQGGDYYRGLAPKKG
                     LAFARIIGHKSFVYQEGLEQRARKEVGGNYGLLTWMTPTRSTQSYMLHQGTKFAERFDA
                     NAYIRIADMWAEFDIRDHTPDGTFQTALEGFRRAGIPALIFSIDTDCCFRPAEQQDFAA
                     QLEAAHIPTEFHTIASTKGHDSFLLEPELYAEPIRRILEARKPKGTA"
     CDS             12586..12996
                     /locus_tag="ctg4_10"
                     /transl_table=11
                     /translation="MTDHYYTSETENVGQFRCETTFIPSNVTFATDLPASFEGRAEFPS
                     PGVLLGSTLASCMMSLVSVVAARKGVDLKGMRVLARAAESSKGIEKIELKAIMPLEGSH
                     PLRAMLEKTALSCPVRQALRPDLETPIEWEWK"
ORIGIN
        1 tccgaatttg caatccgcca cccgaattcc cacatggttt gccccgggca ttctttgctc
       61 atactatttt ttcattgccc ggagttatgg attcctgcat catggccttt cgcagtaccc
      121 ctgcttatga tacacatgac tttaagaaag aaaactctct ggtttcttgg agctttgagc
      181 ttttttgcct ctcttgccgc ggctttcgct gttttctggc tgaacaggaa tgattcttct
      241 cccgcagaat ggaatttcaa ccctatctgg acaaaagcgg aaaaagaaca aattcttacc
      301 gcagcgaatt tcacagccca tcgaagcccg gaacgtttca tttaccgcgg gctttccctc
      361 aattcacgcc atattgactg gcacatgttt tccgaggttt ccatgcgcca atatatgaag
      421 gacgaaatca gggaacggct tcagatgata cgggacacgg cggaaagcgc agacggacgc
      481 tgcatcactc catcccatga aaccctgctg catctcgccg ccgggctcgg agaagtgcag
      541 ttgctgaacc gccttttaca gcgccatgcg gacccgaacg tccagatcat cctgccgcaa
      601 caggcctttc cctccattcc ggactccgaa cagggaaata cccccctgac ttacgcctgc
      661 cagccaggca tggacgactc cacgcccctg ccggtgcata acaggctctc ctgccttaat
      721 ctcctgattc agtacggtgc ggatgtgaat aaaccggggc cgctgggctg gccgcccctc
      781 atcatcacct gtgtagccgg tattggagga gcaccctatg aggaagcggc cctgtttctt
      841 ctgaaatgcg gtgcggatat ttccctccag cctgaattga aaggtaaaaa aacaagtctg
      901 ctcacatggg ccgcggccgc cggatacccc ctgctggtcc gcaagctttg cgaagccggg
      961 tacgatccca atttccgcgg ggaaatggcc ccgccccttc tttccctgaa cctgaacact
     1021 ccgaacgccg cactgcaaat tgcacatatt ctgctggaat acggagcgga cgtgaatgcg
     1081 gccatgcccg cgtccaccac cctgccggaa acagcgggag acacggccct gctaaacctg
     1141 tgccgccagc tggctttcat tgatgtgtcc tgcctccctc aaatcaggga tctggtcaat
     1201 ctcttcatca aagagggagc tgacgtcaac catcaaaacg ccgccggaga aactcccctc
     1261 atggcatgct gccgaggcat gctgctggga gacgattccc tggaccggct gaaactgggt
     1321 attgcgcgtc ttctgctgga ccaccacgca aacccatccc tgaaagacaa atacggacgc
     1381 acagccctcc agaggatagg caaccggtca aacgaacatc tccagatggt gctgaaatac
     1441 ctgccggaat taagcgctcc gccgcttccg aagaaggaaa accattgaat cccgccgatc
     1501 cttacttcac ccgggcattc accgtatcca gcagaatgcc ggcatccggt tgggacccgg
     1561 tgctgatgaa atggatataa ctgactccat taggggactt attagccatt ttcaacgttc
     1621 cggccttctt tccgtccaga gacaccacgg cctgcccacc ctgccaaaga agggaaattt
     1681 catgccacgc gccgggcgag aaaggcactt ttttcatccc cagcaacaga tggggcgcag
     1741 gtctcagcct gatcgggaag gtaaacaggg cataatcctt cgtagtggaa tcacaggcat
     1801 tgaacagccg gtccgtcaga gagacctgaa ggccggaatc atccgcctgc tccccgtccg
     1861 ctacacggaa gcggaatttg accaaccccg tggtcccgtt cggaaagttc caggtagctc
     1921 cgccgttccg gtaatccaca ttggattttt cattgaccag ttcgggatca tccagacgct
     1981 tgatttgcaa caccttcttc gtgcccccgg acggatcctg aaccagctcg gcggaaggct
     2041 tgcggttata actgcaatgg ccttttttct gggggatata agtgtgaatg gtccactggg
     2101 aatccaaatc tttccccgtc tgcgtggcac gcgtcttggc ccctacccag cggcggtcca
     2161 caataaccag gcggcggtgg tttttatgct gccccaggga aataaggatg cggtttttgt
     2221 ccagctgcac catttcgctc tggtgtttgc cgcggtcttc cggaccatcc agcgtagcat
     2281 agccgggatg gttgcggtgt tcgtccagga taatctcccg gaacccgtac caggttttgc
     2341 cctcgtcccc ggacatagca atgtggtggg aatcacggtt ggtgaataca tcctcccacg
     2401 ttccgttgcc agctgtggca ttttcaggca gagccattgt attcgtccac agggaaacga
     2461 tagttccgtc atccaggcgt cccaacgtgt tcatggtcag ggtgccgaaa aagcgggaag
     2521 gctccggttt gctccacgtt tccccgtaat ccttggaaaa agcctgccac gcctggtcct
     2581 gggaggtgcg ggcaagcgcc cacaacgtac cgtctttcat ttccaaaacc gtggcttcca
     2641 cggcattgtt gaaccatctg acgccctggt gggggggcct ggcttcatgt ctgggggaag
     2701 taacaccgtt cctggataca tgccaggtca gccccccgtc atcggaaata tggaacttgg
     2761 tgccgccgcc catgttgtgg aacggcacga tcaccctgcg gcccttgttc acaaaaacgg
     2821 gggtccgcat gatgccgccc agttttttca ggtttttcct cttttccggg tctttccagt
     2881 cttcttccag tttgccgtca ttcgtgacgg caagccactt gccgtccagc ccacccctgg
     2941 aaagaaatac aaagcccccg ataggctgca cacgaatgaa ttccctggtc agagggttgc
     3001 gcacaatagc cggagattct ttgggaatgc caccgtagtt gggagggtag ccagccggag
     3061 cggccttcat ttcccatgtt tttccgttat ccctgctgac caggtaatcc ggttccttgc
     3121 gggtaccgga ataatggcgt atttcacggg agtccacacg gataaggccg cgccccgcat
     3181 cagccggcgg agtggcgaca acttcaggtt ccggaacggg tgcggccttc tgttgggcat
     3241 aacagcaaca aaaggaaccg gtcaacaatg caaacaacag gtttttcata aactaaatat
     3301 caaaggccgt atattttcct caaccggggc tttcccttca agcaaaatcc taccttccat
     3361 cagaagacga tcatcaggaa tgctttcccg cctgcttccc tccccggtat tttgcatcaa
     3421 gctttttcag gagtacggcc agttcctttt ccaaaacctc gtaccccctg gcattgggat
     3481 gcaccacatc cttcatgaat tcattctgcg gagaagcacc atctgcggaa agaagcgcct
     3541 ttcccggatc ggcaaagaaa atgtcctttc cgttatgcag ttccgccaac agtctgttcg
     3601 tctgcttcac cggttccgcc aggtttttct ccttccgtgg gagaacgccc agcaacagga
     3661 ttttggaaga ggggcacttc cggcgcacta ggcggacaaa tgccctgata ttgtccgcac
     3721 atgcctgcgg cgtatccttg cggtgcccca gattattggt ccccagcaac acaatgatga
     3781 cccgcggaga aatgccgtcc agctccccgt tttggacacg gtaataggca ttatccacat
     3841 aatcaaatcc aaagcccata ttcgtcgctg catgcggacc gaataatttc tcccaggacc
     3901 ccgatcccgt attttttccg tccccggaag gctcccctcc ccaatggtgg gtaatgctgt
     3961 cccctatcat cacgtattca ggcttgacgg cccggtttct ttttttaacg gcttcatgcc
     4021 gggcattcca atcatacggg tcccgctgat ggggctccgg cttcagggta gcgggcaacg
     4081 cggaggccgg aatggaaggc gcagaaaatg ccagactgga actccccagc aatatggcga
     4141 gcatgtagga gaggaaattc ataatcaaaa agtaaaaccg gttttcagtt taagcaaatt
     4201 ctgccgtgca tcaagatcgc aggcgtcact tcctccggca gagtaaaaaa gaccactgcc
     4261 cgtccggcaa atcctgccgc aaccacggcc aggcgagcac cgtgtccggc ctcttccaag
     4321 gcgcgctcca tttcatccat cccccggcct ctcccggaac aggaacgccc tcccccgtat
     4381 tcatctaccg gggagcgggc agcttgccgt acttgtcgtc cattttcttc agcaatacgc
     4441 tcaacgactt ccccagtatg tcgtaccccc tggcactggg atgcagccca tcctccagca
     4501 gcccgggttt tggggacact ccgtcctccc ccaggaattc ctcgccggga ttggcgaaaa
     4561 acacgctgtt tccgtcagcc aggccggata tcattttatt ggtttcccta atcaggggag
     4621 ccagcttttt tccctccctg gggagaatgc ccagcaacag gattttggaa gagggacact
     4681 tccggcgcgc caggctcaca aaagccttga gattgtctgc gcaggcccgg ggagcatcct
     4741 tccgcccgcc aagattattg gttcccagca gcacgatgat gacccgcgga gaaatgccgt
     4801 ccagctctcc cagctgcaag cggtaatagg cattatccac gtaatcggaa ccaaacccca
     4861 tattggttac cgcatgggaa gaaaacaggc tatgccaggc ggtttttcct gttccgagag
     4921 ccctgttgtc cccggaaggc tcgccgcccc agcggtgggt aatgctgtca ccaaagacga
     4981 catattccgg tttgacggtc cggttccgct ccatcactgc ttcatgacgt tttttccagt
     5041 catacacggc ccgcgggttc acctggggct tcagcgtggg cggcaattca tcagcacagg
     5101 caccggagaa acaagcaacg caaaaaactc ccgccagcaa taaacaaagg catgcataag
     5161 atttcataac ggtaagcgtt gagatactgc aatagagatt aggaaagtaa agagaaataa
     5221 tcttccgtca cttttccgca atcgcatgtt cccctcattt tccgctccgc aacggacaga
     5281 caggtgaaac atgccaaagc cagcgcaccc gcgttctctt cgcaaagaat tagccttgtt
     5341 gtcccccgga attcacgata taattacgcg gcgcggagtt ttgccgtttc cagcctttca
     5401 ggggctgcgg aacgtttttc tccagtcttc ttcactacat tctatttatg atcagcatag
     5461 taaaagactt gaaggagtcc accgcccttc cgcaggaatg gcagggattc aagccgggaa
     5521 catggacgga gtccattgac gtacgggatt tcatccagca taactacacg ccctattccg
     5581 gcaatgaaga gtttctttcc ggcccctccc agcgcacgct tcgtttatgg gacgagctga
     5641 aagtcctgct gaaacgggaa atagacaacg gcggcgtgct ggatgctgat gaagaagtgg
     5701 tatcctccat cacatcccac aagcccggct acattgacaa ggaactggaa gtggtcgtag
     5761 gcctccagac ggacgccccc ctgaaacggg ccctgatgcc ctttggcggc ttgcgcatgg
     5821 cccaacaggc cctggaatcc tacgggttca agatgtgcga gaaaaccgca gacattttca
     5881 aaaagatacg caagacgcac aatgaaggcg ttttcgacgc ctacacttcc gatatccggg
     5941 cggcccgttc cgccgggatt attaccggcc ttccggacgc ctatggccgc ggccgcatca
     6001 tcggggacta ccgccgggtg gccctgtacg gcacggataa gctgattgcc gaacgccgca
     6061 aggacctcaa aaaccgtgaa cattcccccc ttacggatga gctgatccgt ctgcgcgaag
     6121 aaatgagcga acaaatacgc gccctggaag aactcgccca gctgggcgcc tcctacggct
     6181 gcgacctcac tcgccccgcc gcaaacgccc gcgaagccgt gcaatggacg tacctgggct
     6241 acctagccgc cgtgaaggaa cagaatggag cggccatgtc cctgggccgc gtttccactt
     6301 tcttcgacat ttatttcacc cgcgacctgg aacaggggct catcacggaa gaggaagttc
     6361 aggaaatcat cgaccagttc gtgatgaagc tgcgcatcgt ccgtttcatc cgcacgcctg
     6421 attacaataa cctgttctcc ggagacccca cctgggtgac ggaatccatc ggcggcatgg
     6481 gagaggacgg gcgcaccctc gtcacccgca gttccttccg catgctgcag accctgtaca
     6541 acctggggcc ggctccggaa ccgaacctga ccgttctgtg gtcccggaac ctgccggaag
     6601 ccttcaaaag cttctgcgcc aaggtttcca ttgaaacgtc ctccgtccaa tacgagaacg
     6661 acgacctgat gcgcccgcat tggggcgacg actacggcat cgcatgctgc gtgtccgcca
     6721 tgcgcatcgg caagcagatg cagttcttcg gagcgcgcgc caacctcgcc aagtgccttc
     6781 tctacgccct gaacggcggc gtggatgaac tcaagggcaa gcaggtggcc ccgccctccc
     6841 cccgctacac ggaggaaatt ctcaactatg atgaggtgat ggccctgtac gacaagatgc
     6901 aggactggct cgccaaaact tacattgacg cgctgaacat catccactac atgcacgaca
     6961 aatactgcta tgaacgcatt gaaatggcgc tgcatgatcc ggaaattctg cgcacgatgg
     7021 ctacgggaat cgccgggctt tccgtggcgg cggactccct gtccgccatc aagtatgcca
     7081 ccgtaaaagc catccgcaat gaagaagggc tgattgtgga cttcaagacg gaaggggaat
     7141 tcccctgtta cgggaacaat gacccgcgcg tggacgacat agcatgcagc ctggtcagca
     7201 atttcatgga aaaactgcgc aggctccaca cttaccgcaa ttccctgccc acccagtcca
     7261 tcctgacgat cacctccaac gtggtgtacg gcaaaaagac gggcaacacg ccggacggcc
     7321 gccgagccgg ggaaccgttc gcccccggag ccaaccccat gcacggaagg gacaggaacg
     7381 gagccgtggc ctccatgctc tccgtagcca agctgtccta tgacgactcc ctggacggca
     7441 tctcctacac cttctccatc gttcctcagg ccctgggcaa ggaagaacgt gaacgccgcg
     7501 tcaagctcgt ctccctgctg gacgcctact ttgccgctac aggtcaccac attaatgtga
     7561 acgtactgga acggaaaacg cttctcgacg ccatggatca cccggaaaaa tacccgcagc
     7621 ttaccatccg cgtttccggc tatgccgtga atttcatcaa gctgacccgg gaacagcagc
     7681 aggaggtcat caaccgcact ttccacaccc gttaacccgg actgcaagcg gatgccgcag
     7741 gtttttccac aaaaccatga tccggacgga gaaagctccg tcaccggttt ggttcattcc
     7801 gtggaatcct gcggcaccgt ggacggcccc ggcatccgct tcgtcctttt cctgtccggt
     7861 tgcagcctgc gctgccgcta ctgccataat ccggatacct cctacgtgcg gaggggccgg
     7921 ctcaggagcg cagatgatgt cctcaaggaa atagcccgtt accgggattt tttgcaggcg
     7981 gcgggcggcg gcgtcaccct ctccggcggg gaccccctct tccagccgga ttttgccggt
     8041 gccgtgctga aaggctgccg gaaactgggc ctgcacacct gcctggacac ctccggccat
     8101 ctgggcgtga atgcgggcga agaaatgctg gcggatacgg atctggtcct gctggatatc
     8161 aaggcatgga atccgaaacg gtatcgcgcc ctgacaggcg gggaactgca ccctacactg
     8221 gagtttgcgg aacgcctggc ctccctccgc aagcccgtgt ggctgaggta tgtgctggta
     8281 cctggcgtta cggacaatct ggaagaaatt gaggaactct cccgccatgc ggcgcttctg
     8341 ggcaacgtgg aacgcgtgga cgtgctccct ttccaccagc tggggagatt caaatgggat
     8401 gaattgaagc tggactatac cttgaaggac gtcccggaag cgtccgcaga actggcggaa
     8461 caggtccgcg gcattttccg gcagggcggc tttccggatt gcgtgcatta accggatttt
     8521 cgcgctttgg cgccaccaac cgcagcaaac cggacgcagg catccccctc ttccggatga
     8581 ggggccctct cccctccact gcagaatcca tgcaaaaagg aagacgcatt tctggaattg
     8641 ctccggaata cggcatttcc gcaattcctt tcgttatttc atcattcttt acggcaacgg
     8701 cagcattccc gccgtttttt ccgccaacgc cgggggacgg cattccgtcc cttcccagat
     8761 tattctttcc cggaaatttc ccgcaaggct tccagtacgt cccgcacggc aatgtggcgg
     8821 ttgcagggaa catcccggtc acattccttc cggaagcagg gagaacagca ctggtggctg
     8881 taaagggaac ggttgaatgt gcccataggg cggtaaacat ccggaagccg ggtggaaaac
     8941 agagtcacca ccggaagccc ccggaaagaa cagagggacg gcaagtcgcc atccacggct
     9001 actgccgccg cagcgccgtc catgacggga aagagagctt ccggcgcacc caccgccagc
     9061 tccacattca aatgttccgc cagggacgcg gcgcgctccc ggtcttcttc cagagccgcc
     9121 agcaccgtcc gtcccggcag aagggaaacc agctccctcc actgctccca gctccattca
     9181 ctggcgctcc ccaggcggga aaacggagcg attaaaatgg gggcatcttc cgccggggcc
     9241 gcttttttca cagggaacaa agacggggtg gcggcgtcca gcccatgcag cccccccaat
     9301 tgcagataaa gctgcacccg gtgcgccggg ggggcggcgc gcaggacggg ggcctttacc
     9361 cggaacttgt acttccgggc accgggatgc gtgtccagcc cggaaaacat catggggcca
     9421 tacggttcca gcgctttcag ggtttccata tctccatcca gcatgacgcc cagatccagc
     9481 ggtccgtcat tgtaaaattc atctgctgcc aaagcttccc gaagctgctt cagggagtcg
     9541 tgcggcagca catgggtgac ttccggcacc gtcttccata tccccagctg ggcagacggg
     9601 cagacgatgt tcacctgcat gtcgcaccgg acggttttca aagctcgaat caggggaaca
     9661 gtcgccaggg cttcatccag cgccctggga acggctacca gaatgcggta cggcttcagc
     9721 tccatatttt ccaggagcgc agccgttttt ttatcctgcg gggcaaatcg gtcaacggat
     9781 ttccagcgat ggtgcatcca gaacacatcc agcacggatt cccggatcaa tgtttccagc
     9841 cccctgttca cttcaatcgt gtcccccgcc agagagccgt ccgacctgga aaaatccacc
     9901 acattcccca tatccgctat ccagtggccg ggagcatccg tgcgcaccgc tatggccacc
     9961 atgtccgcgc cagccctttt tctcagcaga gcgggcagcg gagtcgtgcc ggtcaccttg
    10021 ccgaaaaagg ggacatacac cccctcccat acgaactggt cgctcagcac gcccagggct
    10081 cccccttcct tgagcatttt catgggagcc ttgatgcctc cctccttgga gaacatctga
    10141 gttccacgtt ccgtgcgccg ctggtacacg tattcctcca tcagcggatt gtcaaactgg
    10201 cggtacatgg acccgtaacg ctccacctcc gggtaaaatg cgcgtattct cgccagcgcc
    10261 tcccagttgc cggagtgggc tatggcgcaa acctgcccgc gcccttccag cacaggcgcg
    10321 gcaaactgtt cgtgccctcc gaccgtcacg caatgcttca actgctcatc cgtcagggtg
    10381 gccgtcttcg cggaacacaa aaaattggca atggtccttt tgaaattttc ccggcttaat
    10441 ttctgcagtt cctttccgcg cagggccgga tccaaaacga tgcgcagatt cctttccaca
    10501 atgttccggc gctggggaag cagatgccac gccacggccc ctgccgcgcg ccccagccgg
    10561 tacagcgttt tcatgcccac gagcttcaac agcccttcca tgagcagaaa ccctttcatt
    10621 cccaaatgat gggcaaacgt attccgggaa gccggggagg aatcaggaga ggaagaatca
    10681 gtcataagga aaaccggaaa agatgttata cgaatcccct ccggtccaca aaccctttat
    10741 tcccccggca gagatccctt cccgcatttt attttcccgg ctaaatgacg tcttccctaa
    10801 atttttccgc cggcgcggaa tccaaagcca tcccatgctt tactgcatct tcctcataaa
    10861 agcatctctg cggagacggc atcttacttt tggcaaagaa atgactttac aattcttaac
    10921 taaacggtat atttcgtctc ccgaaccgaa caccaaaccg gagttataca ccatgaaagt
    10981 tctttcttcc ttagcctcta tgaagcgccg ccacgcagac tgccaaatcg tgaagcgcaa
    11041 gggcacgctg tatgtgatct gcaagagcaa tcccaagttc aaggcccgcc agggcgctac
    11101 ggcaggcacg cgcctttcca aaaagggcgt taagtaatcc ctggcccagc acagatttca
    11161 agaagaccgc cgcccgccgg gtgccggtct ttttttgctg accaagcccc tttccgtaca
    11221 tccatgcagc ttcctgccgt ccaaaccaaa ttcctggatc ttcccaactc cttctccctg
    11281 agaaatggag ctacgctgga caaggttcgc gtcgcctacg aacaatacgg aaccctgacg
    11341 ccgaataaag acaacgccat cctgctgttc catgctcttt ccggcagcca gcacgcctac
    11401 ggttacaatc cggaagtccc gggcatcggt tccctctgga aaccggaaaa ccacgagggc
    11461 tggtggaaca gcatcatcgg ccccggcaag ccgctggaca caaaccgctt ctgcatcatc
    11521 tgcgccaatt acctgggagg ctgctacggc accacaggcc ccgctacccc ctgccctgcg
    11581 gacggccagc cctacggctc ccgcttcccg catgtggagg ccgcagacca ggcacgtctc
    11641 caggcccttc tgctggacag cctgggcata gaacgcgttc atcttatggg cccctccgtg
    11701 ggcggcctga tcgccctcag cttcgcgtgc cagttcccgg aacgggtccg gagcttcatc
    11761 tccatcggct ccggttaccg ggcttccatc gaacaccgcc tgtccctgtt tgaacaaatc
    11821 ctggccattg agcttgaccc ggatttccaa ggcggggatt actaccgggg actggcgccc
    11881 aaaaaagggc tggcgttcgc ccgtatcatc ggccacaaat catttgttta ccaggagggg
    11941 ctggaacagc gcgccagaaa agaggtggga ggcaactacg gcctgctcac gtggatgacc
    12001 cccacccgca gcacgcaaag ctacatgctt caccagggaa ccaagttcgc ggagcgcttt
    12061 gacgccaacg cctatatccg tattgcggat atgtgggcgg agttcgacat ccgcgaccac
    12121 accccggacg gaacatttca aactgccctg gaaggcttcc gccgcgcagg gattcccgcg
    12181 cttatctttt ccattgatac agactgctgt ttccgcccgg cggaacagca ggatttcgcg
    12241 gcgcagcttg aagccgccca tattcccacg gagttccata ccatcgcttc caccaaggga
    12301 cacgattcct tcctgctgga gccggaactt tatgcggaac ccatccggcg cattctggag
    12361 gcaaggaagc cgaaggggac ggcgtaagct ttttcccgcc gcaagaagac acggcggagc
    12421 aacgcttaaa aagaagtgat gccgggaacc ggaagcaaga gggaaaaatc aaccatgtca
    12481 tgaaggaacg gccaggttcc ctgcaaagcg gaacttcacg gctcttcaac gtgaaaataa
    12541 cctgaaccgg atgaacccga acagggtttt cgctgtcaca ccttcatgac tgatcattat
    12601 tacacctccg aaacggagaa cgtcggacaa ttccgctgcg aaaccacctt tattccttcc
    12661 aacgttacgt ttgccacgga cctgcccgct tcttttgaag gccgcgcaga attcccctcc
    12721 cccggagttt tgctcggttc cacgctcgcc tcctgcatga tgagcctggt ttccgtggtc
    12781 gcggccagaa aaggagtgga tttgaaaggc atgcgcgttc tggcgcgtgc ggcggaatca
    12841 tccaagggaa ttgaaaaaat tgaactgaag gcaatcatgc ccctggaagg cagccaccct
    12901 ctccgcgcca tgctggaaaa aaccgccttg tcctgccctg tgcgccaggc gctgcggcct
    12961 gatctggaaa cgcccattga atgggaatgg aagtaagcag ccatcaggga cgtcaaccca
    13021 agcttgaagt tatccttaaa gaaatcccgc ccattcatga aaaaagccgc tgcggaatca
    13081 tccgcagcgg ctttccaatt ggccgacgtt ttttccttta gaagttgtag cggtagccga
    13141 tactcccgtt gatggagctg gagccgctgc ggatatccgc gttgccgtcc acaaaaatga
    13201 cgccctgggt gcccacggga acgctcagcc ccgcgccaat ctggaaggcc gtgcttccga
    13261 ccttggcgcc atacaccgga cgcgtatagg agggatctgc caggaagccc acattagcct
    13321 gcccgcggcg gtctcccata tcctgggaaa cgttcacccg tacttctccc agcgcttcac
    13381 gcccgaagat attggacccc ataagtccgg agagccgggc acccacagcg acagcagccg
    13441 tagtcagttc ctggtcttcc accttcagtc cggcatttcc ggcagaaccg ctttcccgat
    13501 agccgtccat gcgggtcgtc acgatggaag cgttaaacaa aggctggaga atcacgctcc
    13561 tgtcttcatt gagagcgatg tcatacgcca actcgtacat ggcgccgaaa ccggctcccg
    13621 tcgtattgcc gcgggcctgg taagaccccg taccgtaatt caccgtgcgc gtcagcgagg
    13681 catcattcca gccgcccgtc agaatcagca gatgggacca tttacggtac tggtagcggg
    13741 cgaacagatt gacatagtaa ctgtccaggt ctccgtccgc cgtatccgcc gcgctggccg
    13801 tcaggcttcc gtaattggct gtaaacgcag ctcccgcagt gaggcggtcg ttgatatcca
    13861 cgtccatgcc taccgtgcct ccccaggtgg tgagttcgta gccgctttca tcccccctgg
    13921 tgtccagctt ggcataagac ccggttccct gcatccacat atggaagtag ggcatgtctt
    13981 catggacata tgcagggtta acgcccatct gcgccacgcg gttgcgtatc cagcccatct
    14041 ggtcgcgcag ggagtcgcgc tgggcgatgc ccaggctggt aaccgtgctg ccggcggcgg
    14101 cggccagttt gcgggcggcg ccggaatagt cgcctgaatt ctgggaaaga agaacagaag
    14161 tatagaaatc gcgcaaggca gagccttcct ccatgtgata gcgggaattc caaaggatgt
    14221 ccgctccagt ggcggcattc cgcgtcaggg aagagtcacg gaaaatgttt tccgtgcgcg
    14281 ccgtaccggt gaggatgatg gccgtcatgc tgtcattggt ggtcagctcc aggttttcat
    14341 acatggaacc aagaatcatg tcctggaggg tgacattgtc acccagggac accagcgcgc
    14401 cgtccgttgt cttgaacaat tccatattca gcgtttccga actcccggaa accagggtat
    14461 ccagattgtt catgaccagc gtgacttccc ccgtcccgtc tcccagcgta atatttccgc
    14521 tggaggtgac aaagggattg cccaggccgt ccaccgttgt ggaggaagtg gtaatggcca
    14581 ccgtgctgtc ccctgtcacg ctcaagccgt ccgagccaag cgtcagctgg gttttgggat
    14641 cgtccgcgct gccgatattg agcgtgccgc cgttcacggt aatcccctga taggaagcct
    14701 gggcgggatt gccgccctcc cctgccgctc cggccagggt cagcacgcct ccgtcactca
    14761 cattcaggtg ataacctgca ttgcccgcac ccttgatagt ctggacgctt ccgttgccgg
    14821 atttgacgtt gagcgttccg gatgccccgt ccagcgtacc ggtaaaggta tgggaatcgg
    14881 aagagctgat cgtcatttcc gcaccgctca gcttcagagc tccgccgccc tccagtccgg
    14941 aaacggtatt cacggaaccg gttgcggcgg acagggcggc cccttcacgg atatccagca
    15001 ggacaccgtt cagggaagag ccgttgccca gtgtcaggga ggagtctgtt cccgtaccac
    15061 ccaaggtcag cgtaccgtcc ccggagatag tcacttccgt gacatggctg ccggcctgct
    15121 ggccggtaag aaccatctgg gctccgttac ccaaattcag ggttccccct cccacgccga
    15181 cagccagcgt ttccaccgtg gttacacggg aggcgccgtc attccgtccg cccagcgtta
    15241 tgtctccgcc cgcgagttcc agcgtagtaa ggctattgcc tgcaccgttc aggatgatat
    15301 ttccctccga ggaactgaga caggagtcat tcccggtgaa gtttccttct acggtgaggg
    15361 tttccgcacc tttcttgaca aaatccacat ggtccccgct gatggttccg ccgtagctgt
    15421 tgccgccggc gtcaatatcc tgaaccagat ccaccacgac gtggttggag gccgcatcat
    15481 ccgccgtatt cgtcacggtc agcgcaccgt cgctgccaac cagattgctg actttcaggc
    15541 cgtccccgtt ccgggaggct tccggagccc cgttcaagct cacatgaagc gtggtgccat
    15601 taatgccgac agccttgtag ggatccagcg cggcgtaatc gctgatattg gggttgtctg
    15661 aattgggggt ggtgtccacc agatagacaa ggtccgtatt gccgctgacc atcagcgtcc
    15721 cgtccgcacc caggacttcc gtcacggtat agccgaggga agccaggaga ggagagaatc
    15781 cgatttgctt gaaattatcc acagccaggg ttcccgttgt cagtacaagc cctacgccgt
    15841 cagtggaatc ccggttggcg gcaagcaggt ccagaacacc ctggttgctg aggttgatgg
    15901 ttgttgtggc ggcggaaagc gtcaggctgt ccgcatcaat aacgccctgt ccggtagttc
    15961 cgcccgctgt aaggctgccg gaatccagtt tcagcgtcac cgtcttgccc gtcatgtcca
    16021 gagcaccgga aacgcctgta agccgggagt aatcctccat gacgatggag ccgaccatgg
    16081 agccggacag gccgcccaga ttgatggtat tcagggctcc ctgcgttccg gcggaagcgg
    16141 ccacttccac gtttccggcg gttttggctt ccgcgtttgc caggcttccc ttcgtaatca
    16201 gaataacgtt ggccgcatcc agcgaggaca gattgagaac accgttattg acggtgaccc
    16261 gtccggaccc cagggagtcg gcccccgcca aggtgacggt gcccgttccg gagagcgtcg
    16321 tggaaccggt gaacccggtg ttgccggccg ccagcgttat ctctccggca gtgtcaataa
    16381 ccagggaacc ggctccggag agggacccgg cccaggcact tccgtcaccc agccgcgccg
    16441 tagcgccgcc cgcaatggag agtgcgccca ggaaggtgtt cgctccggtg agttccagcg
    16501 ttccggcgtt tacggatacc gtgctgccgg ccgtaccgct gatgacgcct ccgtaggaga
    16561 aatcgcgggc aaaggccagc gtggagttgt tctggatgtc aatgctgtcc cccagcttgg
    16621 ccacatcggc ggaattcacg gtaaccgtgc cgcggtgcac cttgagctga ccgtccaggt
    16681 tgacgccgcc cgccagggta atattgcccg ctccctgggt ggagaacgcc gttccgctca
    16741 aatcgccgct gaaggtgaaa tccttggtgg caaagacctg gttgcccgta aagacaacgt
    16801 cattggcaaa ggttcctccg gctgttccgt tccattccgt acggacgttg gaatccgcca
    16861 gtttcaagat gccgtccgcc cccatcgtta cgttattcaa ttggaaatag ccggatgtca
    16921 cggacaggat cccctggaat tccgtgctca tattcaggac attggcccca tagctggttc
    16981 ccagtcccac ggaaacggta ccggaaccgg aggcattcag gttcagagcc gagttatcat
    17041 tagccccgct gaccgtcagt acggaaccgt ccaccaattc cacggctttt ccattggcca
    17101 gagccttggc gacggtggcg gccacttcct cgcccagcgt cacggaaccg cccgtccacg
    17161 tcatgttgtc tgcggtaaac gccgtggcaa aagagccgga agccaaattg aggctgccgc
    17221 cctgcaggtt gatcatgccc attcccggct gaacgtccgc cgtagccaga gtgagcacgc
    17281 cgtccgtaac ggtaatggct ccggatccca gggaattggc gacctgggct accagttcgc
    17341 cctgctggac ggaaatatcc ccgttccaac ccgtgttgtc caaattaagg accagcttcc
    17401 cttcgccgcg cttggtcagc gttccctggg cgattttccc ggtgccgttg gaaacgaaga
    17461 cataatcgct tccggcagca ttgttgactg tgatggaagc aggattcacc gctccggaca
    17521 gagtgacggt tcccgccccg gtactgttga agatcagatt cttcccggca gccgtatccg
    17581 tggaaccttc aatgccccac atggcgcccg tgttcgtatc gctccaggtc actccttccg
    17641 ctccctgcca gatccatacg tccccggcgg aagtcactac cagcttgagg gatgttcccg
    17701 tctgctccag ttcataaatc agcgtttcgt ccccggtata tccggcccag ttaaagacgg
    17761 cgctggcggc atcaagaccg ctggcggcgg aaatcagggt atattccccg gcatccgtaa
    17821 tgccttcaag cccgttcagc gtaagattga acgttccggc cccgaaagcg ccgcccactt
    17881 cgagggcgga gctgatatcc agtgtcagcg tagagttggc cgccaggttc agggcgcccg
    17941 cagtcgtcat ccgcgtattg gccgccatcg tgatattccc cagggacgta gccccggaag
    18001 cagtaagagc gagcgttccc ccctgaatat ccgtcagccc cgtgtagctg accgttcctc
    18061 ccagcgtcag cgtttcctcg ccgaccttgg tcagagacag gacgccggat tcgtcatacg
    18121 aaatggaagt ggctccgtac ccaagagcaa caccacggtc tgtgagcgtg ccgttgtacg
    18181 tgccggcccc caccgtcagc gtgcgcgcac cgcctacggc tcccacctgg gaattttccg
    18241 ttccgtccag agaggcaatt tcaacatccc ccagcacgcg catgaaagcg aatccggtcg
    18301 tgtccgttcc ggatgtcagg gtgacgccac cctgagagat ggaagtgcgc agatccagcc
    18361 cggtgctata gccgttggaa gcattcatgg tgatcattcc ggtaaatccg gaagcgtctc
    18421 cgctgatgat gagctttccg ttggaattgt acctgccgtc gcccgctccg cggctgtaag
    18481 tcagagaacc ggctccggtg agcgttccgg t
//
