LOCUS       c00074_gnlPro..        12906 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KKMBOKBE_74.
ACCESSION   c00074_gnlPro..
VERSION     c00074_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 15:14:02
            Original ID  :: gnl|Prokka|KKMBOKBE_74
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12906
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12906
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2803:6361](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2804..6361
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..12906
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..12906
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             complement(231..1385)
                     /locus_tag="ctg74_1"
                     /transl_table=11
                     /translation="MALASGETNYMAPASARQMASDLALLPMWYAEAGSAVLAPSAYNA
                     DFLKTKSELLGMDVALLTEPEVADGKDWKFSPWGWDPALRKRLMTLGAGQTELPSADYM
                     NILREHSHRLQAVKLLPGLRLNEYFCGESFYLSTLAECSAFVEGREACLLKAPLSGSGK
                     GLNWCKGIFTTFISGWCARVAASQGGVVGEPIYNKVEDFAMEFYADGRGRVVFAGYSVF
                     HTGGSGMYAGNDLLSDEKILQKLSAYVPQEEFIRLRTRLEEELSALFGGFYHGYLGVDM
                     MICHFPDEAPVYRIHPCVEINLRMNMGVVAWLLTDRYLAADAEGVFRIDYYPLAGQALE
                     EHRQMSASFPLSVENNRVCAGYLPLVPVTPQSRYRAFLLLTLPQ"
     CDS             1565..2770
                     /locus_tag="ctg74_2"
                     /transl_table=11
                     /translation="LPAEKQRNEMESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGI
                     KGTRGVGKTTFLLQYAKEKFGTDRSCLFINMNNFYFSGHSLVDFANEFQKRGGKVLLID
                     QVFKHPEWSKELRMCYDRFPSLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREFL
                     NLQTGMKFRAYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENL
                     LKTMNMMVEVDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDVQTSRATVMN
                     YIKYLADARLINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNTLW
                     KDHKVHKGDKNVSFMVDEVMPFKICAEGTKIKNNPDVTYALQKAEIGRGNQIPLWMFGF
                     LY"
     CDS             2804..6361
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg74_3"
                     /sec_met_domain="PFOR_II (E-value: 4.5e-19, bitscore: 58.2,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 6.5e-83, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7.1e-32, bitscore: 100.3,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.3e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.3e-12, bitscore: 37.2,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 4.2e-08, bitscore: 22.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.3e-05, bitscore: 14.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.1e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMKPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKSIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQIISVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIAMEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLTVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNAENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKAFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKSKQHLVDIKANVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTMNEKGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARLVKVMNEAIASDCCPAEYKEVFAEWINNMLDAEKTKE
                     LAEKIIPMVEAAKDKCNHCKQIADLQQYLVKRSQWIIGGDGASYDIGYGGLDHVIASGK
                     DVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQIA
                     MGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLWR
                     YNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPAEAEELFKAAEENAKW
                     RYNSYKRLARENWGADTAE"
     CDS             6486..6674
                     /locus_tag="ctg74_4"
                     /transl_table=11
                     /translation="MIGFVIWIIGLILTFRAAIEIWNINAAVEKRLIAIVLIVLTSWLG
                     LLFYYFYGKERMAGWLK"
     CDS             complement(6685..7545)
                     /locus_tag="ctg74_5"
                     /transl_table=11
                     /translation="MNKIKMIAAMFIAGILLTFVSCGDNGKSKKISIAYANWSEGIAMT
                     NLAKAIFEDQGYDVKLLNADLAPIFTSISRKKADVFMDVWMPVTMEDYMKQYGDKLEVI
                     GDIYDGARIGLVVPDYVTINSIEELNAEKERFSGQIVGIDAGAGIMKATDQAIKDYGLD
                     YKLMTSSGPAMTASLKKAIDKKDWIVVTGWTPHWMFDRFKLKVLQDPKLIYGNTESIHT
                     IAWKGFSEKDPFAAELLGNIRLTDAEISSLMTALEEAQTTERQAARQWMEEHQELVNSW
                     IPEKD"
     CDS             complement(7573..8403)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 91.7; E-value: 1.6e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg74_6"
                     /sec_met_domain="BPD_transp_1 (E-value: 2.6e-29, bitscore:
                     91.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIETAINWLTEHFASFFDALSMGIGGFIDGFQHVLFGIP
                     FYITIAVLAALAWFKSGKGTAVFTLLGLLLIYGMGFWEETMQTLALVLSSTCLALLLGV
                     PLGIWTANSDRCNKIMRPVLDFMQTMPAFVYLIPAVLFFGLGTVPGAFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATPWQLLYKVQLPLALPTILTGINQTIMMSLSMVVIA
                     AMISAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIVLDRITQGMADNRKSKKK"
     CDS             complement(8400..9626)
                     /locus_tag="ctg74_7"
                     /transl_table=11
                     /translation="MSKIEIKDLYLVFGNEKQKALKMLKEGKTKSEILKATGCTVAVKD
                     ANLSINEGEIFVIMGLSGSGKSTLLRCINRLIRPTSGEVIINGTDIAKVSDKELLQIRR
                     KELAMVFQNFGLLPHRSVLHNIAFGLELQGVKKGEREQKAMESMQLVGLKGYENQMVSE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLTLQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEIVQIGTSEEILTEPANAYVERFVENVDRSKIITASSVMVD
                     KPIVARLKKEGPEVLIRKMRERNLTVLPVVDSNNLLVGEVRLNDLLKLRKEQIRSIGSV
                     VRHEVHSVLGDTVLEDILPLMTKTNSPIWVVNENREFEGVVPLSSLIIEVTGKDKEEIN
                     EIIQNAIEL"
     CDS             10100..11386
                     /locus_tag="ctg74_8"
                     /transl_table=11
                     /translation="MFNRAITIFLGKDNCHYTTKEKQTGTATLDDKSQVQFLSKKNPKM
                     PFFYSRRNLYMIGFLLAFIVTLLEFMRGRHQNFMVFSDATQFFWQGISPYTTEFVEAHG
                     RYFLYSPVFTVLFAPFAYLPAWLGPFAWNLFNYSLFFVAIFTLPQPFTQQQKCRMFLFL
                     LLILGQSLLSFQYNITVAYLFLFAYTLLEKDRGFLAVLLIMISGCTKVYGIFELALLLC
                     YPHVWRNFGYAVAMGIVLLALPLIKIAPADLLPYYEEWCHSLAVHQSTGAYDSFFYARP
                     IAAWTLPHFRALQIGMLGLLTLLFLGNFRKWSSFAFRAQALGILMGWVVLLSDSAEKHT
                     YIIALAGFMLWYWSRPTRTATDKILFWCCFVLLCIVPIDIFVPVPIRDFITRTLWLHVW
                     VFFIVWIRMIWLTFLASFIHPRATNVLSD"
     CDS             complement(11349..11681)
                     /locus_tag="ctg74_9"
                     /transl_table=11
                     /translation="MKDYKVDKESFSESFRKEVYEVVSQIPVGKVSTYGGIALLLGVPQ
                     CSRMVGRALKEVPDELSIPCHRVVNTAGRLVPGWVEQKQLLLAEEVSFKANGCVNLKEH
                     LWHVDE"
     CDS             complement(11723..12904)
                     /locus_tag="ctg74_10"
                     /transl_table=11
                     /translation="LERIYFNLLSNAFKFTPENGKIAVRLSSLSKEDKRWIRFTVANTG
                     SMISAEHIRNVFDRFYKIDMHHTGSGIGLALVKAFVEMHGGMISVESDEKQGTVFTVEL
                     PVQSCEAVAAKPDTTLVSADSRTTDVLLAEEEELEKGYDSSKPSVLIIDDNEDIRSYVH
                     TLLHTDYTVIEAADGSEGIRKAMKYVPDLIISDVMMPGIDGIECCRRLKSELQTCHIPV
                     ILLTACSLDEQRIQGYDGGADSYISKPFSSQLLLARVRNLIDSHRRLKQFFGDGQTLAK
                     EDVCDMDKDFVERFKSLIEEKMGDSGLNVEDLGKDMGLSRVQLYRKIKSLTNYSPNELL
                     RIARLKKAASLLASSDMTVAEXXXXLVMKSVSVHLLISPSAIKSSLERARQIS"
ORIGIN
        1 ctcaattatt aatatctgag aaatcaaacg ttaacagttg agatatcaga tattaacatc
       61 ctgtaaatca aagaataaca cagtaaaaac ggtatttatc aggacgatgc agagtgagag
      121 caagtccttg ctctcactct gctaccactg gatctctaac agctaaaaca tcgatgaata
      181 aagggataca gacgaactgt tagagcatga gagcaaaagc actatctttt tcactggggg
      241 agagtaagca aaagaaacgc acgataccgg ctttgaggcg tcaccggtac taacggcaaa
      301 tatccggcac acacccgatt attctctacg gacaaaggga acgaagccga catctgccga
      361 tgttcctcca aagcctgacc ggctaaagga taataatcaa tccgaaaaac tccttccgca
      421 tccgcagcca aataacgatc cgtcaagagc catgccacca cccccatatt cattcgcaga
      481 ttaatttcga cacaaggatg aatccggtaa acaggcgctt catccggaaa atgacaaatc
      541 atcatatcca ctcccaagta tccatgataa aagccaccga acaaagctga caattcttct
      601 tccaaacgag tccgcagcct gataaattct tcttgtggca cataagccga tagtttctgc
      661 agaatcttct cgtcagacag caagtcattc cctgcataca tcccactccc acccgtgtgg
      721 aagaccgaat atccggcaaa aacaaccctt cctctcccgt cagcataaaa ctccatagcg
      781 aaatcttcca ccttattata tataggttcg cctaccaccc caccctgaga agcagcgaca
      841 cgggcacacc aaccggaaat aaaagtagta aatatgcctt tacaccaatt caatcctttc
      901 ccgcttccgg aaagcggagc ttttaacaag cacgcttccc gcccttcgac gaacgcactg
      961 cactccgcca aagtactcaa ataaaaagat tctccacaga agtattcatt caaccgcaac
     1021 ccaggcaaca actttaccgc ctgcagacga tgcgaatgct ctctcagaat attcatataa
     1081 tccgcagaag gcagctccgt ctgacctgcc cccaatgtca tcaaacgctt ccgcaaagca
     1141 gggtcccaac cccacggaga gaacttccag tctttaccgt cagccacttc cggttccgtc
     1201 aacaaggcca catccatgcc caaaagttca ctctttgttt tcaggaagtc cgcattataa
     1261 gcagacggtg caagcaccgc acttcccgct tcggcatacc acataggaag caacgccagg
     1321 tcactcgcca tctgtcgggc ggaagccggc gccatatagt tcgtctcacc gcttgccaac
     1381 gccatatcat gctccggatt gaatatataa acaggtcttt tcgtcatgtc aaagatggat
     1441 tcaacacatt attctgcaaa tatatacagg aaataatcag gaacttacac aataaagaga
     1501 aacttataaa ttaaagcaca tttttgctat ctctactttg caaatcctaa aaaaagcact
     1561 atatttgcca gccgaaaaac aaagaaacga aatggaatca ttctatcgca cacacgccta
     1621 cctcgttgag cacaccaatg cccccgttcg ccgcgatctt atggacgaga tcgactggag
     1681 tgaccgtctg attggtatca aagggacacg tggcgtagga aaaaccactt tcctcctgca
     1741 gtacgccaaa gagaaattcg gcaccgatcg ttcctgtctg ttcatcaata tgaacaactt
     1801 ttatttctcc ggtcacagcc ttgttgactt cgccaacgag tttcagaaac gtggcggaaa
     1861 agtactgctg atcgaccagg tgttcaaaca tcccgaatgg agcaaagagc tacgaatgtg
     1921 ctatgaccgt ttccccagcc tgaagattgt cttcaccggt tcttccgtca tgcgactcaa
     1981 agaggaaaac ctcgaattgc gtgacattgc gaaaagttat aacctgcgcg gattctcttt
     2041 ccgtgaattt ctgaacttgc agacaggaat gaaattccgg gcatacagcc tcgaagaaat
     2101 cctcagtaca catgaacaga tagccaaagg agtactttcc aaagtacgac cgctggatta
     2161 ttttcaggat tacctgcatc atggtttcta ccctttcttc cttgaaaaac gaaatttctc
     2221 ggagaatctg ctgaaaacaa tgaacatgat ggtagaagtg gatatcctgc tgatcaaaca
     2281 aattgagctg aaatatcttt caaagataaa aaaattacta tatttgttgg ctgtggacgg
     2341 accgaaagct ccgaacgtga gccaactggc aagtgacgta cagacatccc gcgctacggt
     2401 aatgaactat atcaagtatc tggcagacgc gcgtctgatt aatctggttt acccgaaagg
     2461 agaagaattc ccaaagaaac cgtcaaagat tatgatgcac aactctaacc tgatgtactc
     2521 catttatccg gtgaaagtgg aagaacagga tgtactcgac acgttcttcg ttaacacttt
     2581 atggaaagac cataaggtac ataaaggaga taaaaacgtc tctttcatgg tagacgaagt
     2641 gatgccgttc aaaatttgtg cggaaggtac aaaaataaag aataacccgg acgtgacgta
     2701 tgcgttgcaa aaggctgaga taggccgcgg caaccaaata cctctctgga tgttcggatt
     2761 cttatactaa aaagatttat ttacttaaat atttaattta gttatgacta aacagaagaa
     2821 attcatcaca tgtgatggta accaagctgc agcacatatc tcgtatatgt tctctgaagt
     2881 agcagctatc taccccatca ctccttcttc gactatggct gagtacgtag acgaatgggc
     2941 tgccgcagga cgtaagaaca tcttcggcga aacagtattg gtacaggaaa tgcaatctga
     3001 aggtggtgct gccggtgcag ttcacggttc tcttcaggct ggtgcattga ctactactta
     3061 cactgcttct cagggtcttc ttttgatgat ccctaacatg tacaagattg ccggtgaatt
     3121 cttgccttgt gtattccacg tttctgctcg tacactggct tctcacgcat tgtgtatctt
     3181 cggtgaccat caggacgtaa tgtcagctcg tcaaaccggc ttcgctatgt tggcagaagg
     3241 ttctgtacag gaagttatgg atttggcagg tgttgctcat ctggctacta tcaaatcacg
     3301 cgttccgttc atgaacttct tcgatggttt ccgtacttct cacgaaatcc agaagatcga
     3361 aatgttggaa aacgacgacc tcgctccgct gatcgaccag gaagctttgg ctgaattccg
     3421 tgcccgtgca ctgaatccga tgaagccggt tgcccgtggt atggctgaaa accccgacca
     3481 cttcttccaa catcgtgaat catgcaataa ctactatgaa gcagttcctg ctatcgtaga
     3541 agaatacatg aacgaaattt ccaagatcac aggccgcaaa tacggtttgt tcgattacta
     3601 cggtgcagaa gatgcagaac gcgtaattat cgcaatgggt tctgtaactg aagctgcccg
     3661 cgaagctatc gaccacttgg tagcaaacgg cgaaaaagta ggtatggttg ccgtacactt
     3721 gtatcgtccg ttctctgcta aacacttcct ggctgctgta cccaagactg caaagagcat
     3781 cgcagtgctt gaccgtacaa aagaaccggg tgctaacggc gaacctcttt accttgacgt
     3841 taaagactgc ttctatggcg cagaaaatgc tcctgttatc gttggcggtc gctacggtct
     3901 gggttcaaaa gataccactc cggcacagat catctctgta ttcgaaaact tggctatgcc
     3961 aatgccgaag aaccacttca ctatcggtat cgtagacgac gttacgttca cttctcttcc
     4021 tcagaaagaa gaaatcgctc tgggcggtga aggtatgttc gaagctaaat tctacggtct
     4081 gggtgctgac ggtacagtag gtgccaacaa gaactctgtt aagattatcg gtgacaacac
     4141 cgacaaacac tgtcaggctt acttctctta cgactccaag aagtcgggtg gtttcacttg
     4201 ttctcacttg cgtttcggtg atactccgat ccgttctact tacttggtaa atactccgaa
     4261 cttcgttgct tgtcacgttc aggcttacct gcacatgtac gacgtaacac gtggtttgcg
     4321 taagaacggt tctttcttgc tgaacaccat ctgggaaggc gaagaactgg ctaagaacct
     4381 gcctaacaag gtgaagaaat actttgcaca gaacaacatc tctgtatact atatcaacgc
     4441 aactcagatt gcaatggaaa ttggtttggg caaccgtacc aatacaatcc ttcagtctgc
     4501 attcttccgt atcacaggcg taatccctgt agatcaagct gttgaacaga tgaagaaatt
     4561 catcgttaag tcttacggca agaagggtga agacgttgtt aacaagaact acgctgctgt
     4621 agaccgcggt ggtgaataca agactctgac tgtcgatcct gcttgggcta acctgccgga
     4681 tgatgcaaaa gcagaaaaca atgatcctgc tttcatcaac gaagtagttc gtccgatcaa
     4741 tgcacaggac ggtgacttgc tgccggtatc tgcattcaag ggtatcgaag acggtacttg
     4801 gtatcaaggt acttccaaat acgaaaaacg tggtgtagct gcattcgttc ccgaatggaa
     4861 tgctgaaaac tgtattcagt gtaacaagtg tgcttacgtt tgtcctcacg cttctatccg
     4921 tccgttcgta ctcgatgctg aagagcagaa gggtgctaag ttcgagcaac tgaaagctgt
     4981 aggtaaagca ttcgatggta tgacattccg tattcaggta gacgttctcg actgtctggg
     5041 ttgcggtaac tgtgccgaca tctgtccggg taatccgaag aagggtggta aggcattgac
     5101 catgaaacac cttgaaagcc agttggccga agctgataac tggacttact gcgctgaaaa
     5161 cgtgaagagc aaacaacacc tggtagacat caaggctaac gtgaagaact ctcagttcgc
     5221 aactccgttg tttgagttct caggcgcttg ctccggttgt ggtgaaactc cgtacgtgaa
     5281 actgatttct cagttgttcg gtgaccgtga aatggttgct aacgctacag gatgttcttc
     5341 tatctactcc ggttcagttc cttctactcc gtacactatg aacgaaaagg gtcacggtcc
     5401 tgcatgggct aactccttgt tcgaagactt ctgtgaattt ggtctgggta tggaactggc
     5461 taacgaaaag atgcgtgccc gtctggtgaa agtaatgaac gaagctatcg cttctgattg
     5521 ctgcccggct gaatacaaag aagtatttgc tgaatggatc aacaatatgc tggatgcaga
     5581 aaagactaag gaactggccg aaaagatcat tccgatggta gaagctgcta aagataaatg
     5641 caaccactgc aagcaaatcg ctgatctgca acaatatctt gttaaacgca gccaatggat
     5701 catcggtggt gacggtgctt cttatgatat cggttacggt ggtcttgacc atgtaatcgc
     5761 ttccggtaag gacgttaaca tccttgtatt ggatactgag gtttactcta acacaggtgg
     5821 tcagtcttct aaagctactc cggtaggcgc tatcgctaag tttgctgctg caggtaagcg
     5881 tgtacgtaag aaagacctcg gtctgatggc tactacttac ggttatgtat atgttgctca
     5941 gattgctatg ggtgctgacc aggctcagac tctgaaagct atccgtgaag ctgaagcata
     6001 tccgggacca tcactgatca tcgcttacgc tccatgtatc aaccacggtc tgaaagccgg
     6061 tatgggtaag agccaggaag aagaagaaaa ggctgttaag tgcggttact ggcacttgtg
     6121 gcgttacaac cctgctttgg aagaagaagg caagaatccg ttccaactgg atagcaaaga
     6181 acctaactgg gaagacttcc aaggtttctt gaagggtgaa gttcgttacg cttctgtaat
     6241 gaaacaatat cctgctgaag ctgaagaact gtttaaagct gctgaagaaa acgctaaatg
     6301 gcgttacaac agctacaaac gtcttgccag agaaaactgg ggagctgata cagctgaata
     6361 ataagtagaa atactttgta cataataaaa ggcaggaatc ctggaaacag attcctgcct
     6421 tttttgttta tatcttagaa gtaacgatta cttctcacga agatattcat taaaactcta
     6481 aagatatgat cggatttgtt atttggatta tcggtttgat actgactttc agagctgcca
     6541 tagagatttg gaatataaat gcggctgtag agaaaagact tatagcgatt gtattaatcg
     6601 ttcttaccag ctggctggga ctacttttct actacttcta tggtaaagaa agaatggcgg
     6661 gatggttgaa gtagtgtttg catatcaatc tttctcagga atccaactgt tcaccagttc
     6721 ctgatgttct tccatccatt gacgggcagc ctgtctttcc gttgtctgcg cctcttccag
     6781 agcagtcatt aaggagctga tttccgcatc tgtcagacga atgttgccca aaagttcggc
     6841 agcaaaaggg tctttctcgc taaaaccttt ccatgctatg gtatgaatgg attccgtatt
     6901 tccatatatc agcttcgggt cctgaagaac tttcagcttg aaacggtcga acatccagtg
     6961 aggcgtccat cccgtcacga caatccagtc tttcttatca atcgctttct ttagggaagc
     7021 agtcatggca ggtccgctcg aagtcatcag tttataatcc aatccatagt ctttgatggc
     7081 ctgatcggta gctttcataa taccggctcc ggcatcaata ccgacaatct gaccggagaa
     7141 acgttccttt tccgcgttca gttcttcgat tgagttgatc gtaacgtaat ccggaaccac
     7201 cagcccgata cgggcaccat cataaatatc cccgataact tcgagtttat ccccgtattg
     7261 tttcatataa tcttccatag tgacaggcat ccagacatcc ataaatacgt ctgctttctt
     7321 acgggagata gaggtaaata taggtgcaag gtcggcattc agcaacttta catcgtaccc
     7381 ctgatcttca aaaatcgctt tggcaaggtt tgtcattgca ataccttccg accagttggc
     7441 ataagcgata cttatcttct tactctttcc gttgtctccg caggaaacga aggttaagag
     7501 tatgccggca ataaacattg ccgcaatcat ttttatctta ttcattgatt attcctttct
     7561 ttggtgtgat tcttatttct ttttactttt tctgttatct gccataccct gagtgatgcg
     7621 gtccagcacg atcgccaata tcacgactgc gataccgcct tcaaatccga gtccgatttt
     7681 catttgggtg atacctttca gcacgatttc tcccaatcct ccggcagaaa tcatggcagc
     7741 aatcactacc atcgaaagtg acatcatgat cgtctggttg attcccgtca gaatagtagg
     7801 caacgccaaa ggcaattgca ccttataaag aagctgccag ggagtagctc caaaagagcg
     7861 ggaggcttct actacgtttt taggaacctg acgaatgccc agaccggtca gacgaaccac
     7921 aggaggcatt gcaaagatga tggtggcaaa agctcccggc acagttccca atccgaagaa
     7981 tagaacggca ggaatcagat agacaaaggc aggcattgtc tgcataaagt cgaggacagg
     8041 gcgcattatc ttgttacaac gatcactgtt ggcagtccag attcccaacg gaacgcctaa
     8101 aagcaatgcc agacaagtgg aagaaagtac caatgccaat gtctgcatcg tttcttccca
     8161 aaagcccatg ccgtaaataa gcaataaacc caagagggta aatacggctg tccccttacc
     8221 cgacttaaac caggcgagcg cagccagcac tgcaattgtg atataaaaag gtattccaaa
     8281 cagtacgtgc tgaaaaccgt ctatgaatcc tccgatcccc atgctgagag catcaaaaaa
     8341 ggaagcaaaa tgttctgtga gccaattaat ggcagtctct atatattgtc cgatatttat
     8401 cataattcta ttgcgttttg aatgatttca ttaatttctt ctttatcttt tcccgttact
     8461 tcgatgatca atgaggaaag tggcactacg ccttcaaact cccgattctc atttacgacc
     8521 cagattggcg agttcgtttt tgtcatcaac ggaagaatat cttccagcac cgtatcaccc
     8581 agcactgaat gaacttcatg ccttactacg gacccgatgg agcggatttg ctcttttcgt
     8641 agtttcagca agtcattcaa ccgcacctct cctactaaca gattattgga atcgactacc
     8701 ggaagaacgg tcagattccg ttcgcgcatc ttacggatca gcacctccgg gccttctttc
     8761 ttcaaacgtg ccactatggg tttatctacc ataacagagg aagctgttat aatcttgctt
     8821 cgatctacat tctccacaaa tcgttctaca taagcgttgg caggttcggt caggatttct
     8881 tccgatgtac cgatttgtac aatttctcca tccttcatga tagcaatccg gtcacccaat
     8941 ttaatcgctt cactcaggtc gtgagtaata aagacaatcg tttttttcat cttcgactgc
     9001 aaagtcagca gttcatcctg catctgcaca cggatcaaag gatcgagtgc cgagaaggcc
     9061 tcatccatca acaggacttc gggattattg gccaaagccc gcgccagccc gacacgctgc
     9121 tgcatcccac ccgacagttc acttaccatc tgattctcgt agcctttcag ccccaccagt
     9181 tgcatgcttt ccatcgcttt ctgctcccgt tctccctttt ttactccctg tagttcgagc
     9241 ccgaaagcta tattatgcaa gacagaacgg tgaggaagca gaccgaagtt ctgaaagacc
     9301 atagccagtt ctttccggcg aatctgcaac agttccttat ccgacacttt ggctatgtct
     9361 gttccattga taatcacttc tccggaagta gggcgtatca aacggttgat gcagcggagt
     9421 aaagtggact ttccactacc ggacagcccc ataatgacga atatttcgcc ttcattaatg
     9481 gaaagattcg catctttcac cgcaactgta catccggtcg ctttcaatat ttcacttttt
     9541 gttttacctt ctttcaacat cttcaaagcc ttctgcttct cattgccaaa aaccagatag
     9601 agatctttaa tttctatttt actcatacaa taaaatggtt taggttatta aaataatata
     9661 cacagcaaga caagaacaaa cgataacagg aatctttctt tatatcgtat aaagttctga
     9721 tttaaatacg ggacaaataa caatgaatcc cgaaataatt aatagaatga ttattgacag
     9781 actgagtaat taaaaaagga atagaatttg ataagataat cctttcaacg aatagcaaaa
     9841 aaatagcatt tttatgtata aaaacagcct gttccagtat cttgctggca caaagataca
     9901 aaaaacagat taaacatgca aattatattc aaaatccggg gcatacagag ggctttattt
     9961 gtaatgatat ggaaagtttt cgggtaatat tcccctatca ctcagcaaaa tagaacaaac
    10021 cggcagataa atataaaata agtttgaata tttcacctaa acaccgtata tttggcgtca
    10081 ataactaaac tagatttata tgttcaacag ggctattaca attttcctgg ggaaggataa
    10141 ttgtcattac acaacaaaag aaaaacaaac aggtactgcc acactagacg acaaaagcca
    10201 agtacagttc cttagtaaaa agaaccccaa aatgccgttt ttctatagtc ggcggaatct
    10261 ctacatgata ggtttcctgc tcgcttttat agtgactctg ctcgaattta tgcgaggacg
    10321 gcatcaaaac tttatggtct tctcagacgc tactcaattc ttctggcaag gcatcagccc
    10381 atacacaacc gaatttgtag aagctcacgg acgctacttc ctttattctc ctgttttcac
    10441 ggtattgttc gctccgtttg cgtatctgcc tgcatggctg ggacctttcg cgtggaatct
    10501 attcaattat tcattgtttt ttgtagcgat cttcacgctg ccccaaccat tcacccagca
    10561 gcagaaatgc cgtatgttcc tctttctgtt actgatttta ggacaaagtt tactttcatt
    10621 tcagtataac ataacggtag cctatttatt cttattcgcc tatacgttat tggaaaaaga
    10681 ccgtggattt ctggctgttc tgttaatcat gatttcggga tgtaccaaag tatatggaat
    10741 tttcgaactg gcattgttgc tgtgttatcc tcacgtatgg cgtaactttg gctatgccgt
    10801 tgcaatgggc attgtattgc ttgcgttacc gttaatcaaa atagctcctg cagatttgct
    10861 cccctattat gaagaatggt gccatagtct tgctgttcat caatccaccg gagcttatga
    10921 ttcatttttc tatgcccgcc ccattgcagc atggacattg ccacacttcc gtgcacttca
    10981 gataggaatg ctcggtctgc tgactctgct ctttttgggg aatttccgca aatggtcgtc
    11041 ttttgccttc cgtgcccaag ctttgggcat tctcatgggc tgggtagtat tactgagtga
    11101 ctccgccgag aagcatacct atattatcgc attggcaggt ttcatgctct ggtattggag
    11161 cagaccaaca cgtaccgcaa cagacaagat tctattttgg tgctgttttg tgctgttatg
    11221 tatcgttcct atcgacatat tcgtccctgt acccatcaga gatttcatta ccaggacctt
    11281 atggcttcat gtatgggttt tctttattgt atggatacgg atgatatggc ttaccttcct
    11341 tgcatccttc attcatccac gtgccacaaa tgttctttca gattaacgca tccgttagct
    11401 ttgaaagaaa cttcttctgc cagcaagagt tgtttttgtt ccacccaacc gggcaccagc
    11461 cttccggcgg tatttacaac tctatggcag ggaatggata attcatccgg cacttctttc
    11521 aatgcacgtc ccaccatccg cgagcattgg ggtaccccca acaacaaagc aatacctcca
    11581 taggtagata cttttcccac aggtatctgg gatacgactt cgtacacttc cttccgaaag
    11641 gattcggaaa agctctcttt atctacttta taatctttca tatatccctc tttacgatat
    11701 caatgaaatc atcctttcct tttcaggaaa tctgtcgggc tctctccaaa ctgctcttta
    11761 tagcacttgg cgaaataaga aggtgaactg aaaccgactt cataaccaat cnnnnnnnnn
    11821 nctccgctac ggtcatgtcc gaagaagcaa gcaaagaagc tgccttcttc aaacgggcga
    11881 tacggagcaa ttcattcgga gagtagttag tcaatgattt aatcttgcga taaagctgca
    11941 cacggcttag tcccatgtct ttgcccaagt cctccacatt caaaccggag tctcccattt
    12001 tctcttcaat caatgacttg aatctttcta caaaatcctt gtccatatcg cagacatctt
    12061 cttttgccaa tgtctgcccg tcaccaaaga actgtttcag acgacggtga gaatcaatca
    12121 gattgcggac acgtgccagc aacagctgtg aactgaacgg ctttgaaata taagaatccg
    12181 caccaccgtc atatccctga atacgctgtt cgtccagtga acacgctgtc agcagaataa
    12241 ccggaatatg acaggtctgt aactcacttt tcagccggcg gcaacattca atgccatcaa
    12301 tgcccggcat catcacatca gaaatgatca ggtccggaac atacttcata gccttacgga
    12361 ttccttcgga gccgtctgcc gcttcaatca ccgtatagtc tgtatgcaac aacgtatgga
    12421 catacgaacg gatatcctca ttatcatcaa taatcagtac ggacggtttg gaagagtcat
    12481 atcctttttc cagttcttcc tcttccgcca atagaacatc tgttgtacgg gaatccgcag
    12541 aaacaagggt ggtatccggt ttggcagcaa cagcctcaca agactgtaca ggcagttcaa
    12601 cggtaaagac cgtgccctgt ttctcatcgc tctctacgga gatcatacca ccgtgcattt
    12661 ctacgaaggc ttttaccaat gccagtccga ttcccgaacc ggtatggtgc atatcgatct
    12721 tatagaaacg gtcgaataca ttgcgaatat gttcggcaga aatcatggaa ccggtatttg
    12781 ccaccgtgaa acgtatccat cgcttgtcct ctttactaag ggaagacaga cggacggcta
    12841 ttttcccgtt ttccggtgta aacttaaagg cattggacag aagattgaaa taaatacgtt
    12901 ccagct
//
