LOCUS       c00206_gnlPro..         6862 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KKMBOKBE_206.
ACCESSION   c00206_gnlPro..
VERSION     c00206_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 15:14:02
            Original ID  :: gnl|Prokka|KKMBOKBE_206
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6862
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6862
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1617:6179]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1618..6179
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..6862
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..6862
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(70..1404)
                     /locus_tag="ctg206_1"
                     /transl_table=11
                     /translation="MKRIILLAFLCTTTLVMAQRINHVQEAIANYDYEAALTLIAKEKP
                     TIPLLLQKGKAQRGLGMNTEALSTYQEIITNDTANTRAYIEAAECCRSLAKYQQALKYY
                     EQALDLNPENKYVRIQYIGLLLSLQKFQDALGESSLMTEKDSSAIALHLQAQSFEGMGE
                     LLPATGCYYNIQEKYPDDYLAAAKLAALNIAGSYFNEAIEATEKYRQIDTTNIAVNRQN
                     ALAYCLNKDYPTAIQRYEYLVSQGDSSFHTCYYLGISYYAEEKYYEAHDFLEAARKHDP
                     ENVNLLYYLGRACAKTSWKKLGVEYLEKALDLTIPKDSNMVRLYIGMTDCYKMAQMPKE
                     QIESIRERYRKYDKQNHKLLYDMAFIYFYSLKDKKNTERCLEAFLKTRPKEDKEEEAKL
                     NERGELVLGTKNYYNAAANWLKDIQSKQKIEDFFLGGNVPAQKPE"
     CDS             complement(1618..2778)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg206_2"
                     /sec_met_domain="OAD_beta (E-value: 7.4e-154, bitscore:
                     500.7, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFINFLGNNLADFWTYTGFANATGGHIAMIIIGLGFIYLAVAK
                     EFEPMLLIPIGFGILIGNIPFNMDAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYMIALEMGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRLLTTKHERVIRMKPPRAVSHTEKVIFP
                     IIGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDVITILLGLTVGAS
                     TQASEFLTLDSIKIFALGALSFIIATASGVIFVKIFNLFLKKGNKINPLIGNAGVSAVP
                     DSARISQVVGLEYDPTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             complement(2780..3214)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 66.7; E-value:
                     4e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg206_3"
                     /sec_met_domain="Biotin_lipoyl (E-value: 4.6e-22, bitscore:
                     66.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNSYKVTIGDIEDNIAHVEVNGTHYKVEMEKQPKAT
                     PKPAVVRPMPNSPAAPTTPVVKPAAPSTGKSGVKSPLPGVILDIKVNVGDTVKRGQTII
                     ILEAMKMENNINADKDGKVTAINVNKGDSVLEGNDLVIIE"
     CDS             complement(3239..4159)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg206_4"
                     /sec_met_domain="OAD_gamma (E-value: 1.9e-15, bitscore:
                     46.2, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLLLLIGLTSCGEQKSNNKLLLNEVLIDNQNNFQD
                     DYGLHSAWIEIFNKSYGSADLAACLLKVSSQPGDTVTYFIPKGDILTLVKPRQHALFWA
                     DGEPNRGTFHTSFKLNPETANWVGLFDSGRKLLDQVVIPAGTLGPNQSYARISDGAADW
                     EVKGGSKDKYVTPSTNNKTLDSNAKMEKFEEHDSVGIGMSISAMSVVFCGLILLFIAFK
                     VVGKVAVNLSKRNAMKAKGIDKVEAKELSQAPGEVYAAISMALHEMQDEVHDVEETVLT
                     ITRVKRSYSPWSSKIYTLRENPNRK"
     CDS             complement(4191..5744)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg206_5"
                     /sec_met_domain="CT_Btheta (E-value: 2.3e-291, bitscore:
                     955.2, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIERRAVARIGGGEKAIAKQHEKGKYTARERIAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYLFAQDFTVTAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAKTEEEGLALIRTLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNDIIPDSPN
                     KPYDMYEVISAIVDNGEFLEIQKDYAKNIIIGFARFNGQSVGIVANQPKFLAGVLDSNA
                     SRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKDQENPAQFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLSNPAKKHGNIPL
                     "
     CDS             complement(5775..6179)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg206_6"
                     /sec_met_domain="Glyoxalase_4 (E-value: 7.4e-25, bitscore:
                     76.4, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGETKIELLEPTCPESTIAKFIENKGAGVHHVAFAVEDGVANALAEAESKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
     CDS             complement(6353..6862)
                     /locus_tag="ctg206_7"
                     /transl_table=11
                     /translation="RQIRKGLKNGAKVVEAHTVEEIKEFSRMLHKVYSSRIRRYFPAND
                     FFRHMNSMLIRGKQAKIFIVKYKEKIIGGSVCIYSGENAFIWFSGGMRKTYALQSPGIL
                     AVWKALEDAHERGFRHMEFMDVGLPFRKHGYRDFVLRFGGKQSSTRRWFRISWPWLNNL
                     LVKFYV"
ORIGIN
        1 atcctattat atagaaaggc tgcaatcgtt tgacggttgc agccatttta cgtaatattc
       61 tctatctgct tattccggtt tctgagcggg cacatttcct cccaagaaga aatcttctat
      121 cttttgctta ctttgaatgt ctttcagcca gttagctgca gcattataat aattcttagt
      181 gcctaaaacg agttcgcctc gttcgtttag tttcgcttct tcttccttat cttctttcgg
      241 gcgtgttttt aagaatgctt ccagacagcg ttcggtgttt ttcttgtctt tcagcgaata
      301 gaaataaatg aaagccatat catagagcag cttatgattt tgtttatcgt atttccggta
      361 gcgttctctg atcgattcaa tctgctcttt aggcatctgt gccattttgt agcagtcggt
      421 catgccaata tagagccgta ccatattact gtctttggga atagtcagat caagcgcttt
      481 ttcgagatac tctacgccta acttcttcca tgaagtcttg gcgcaggcac ggccgagata
      541 ataaagcagg tttacgtttt caggatcatg ttttcgggcg gcttccagaa agtcatgtgc
      601 ttcgtaatat ttctcttccg cataatagct gatacccaga taataacagg tatgaaaaga
      661 actgtcgccc tggctcacca ggtattcata acgctggata gcggtaggat aatccttatt
      721 cagacaatat gccagtgcat tctggcggtt gacagcgatg ttggtggtgt caatctgccg
      781 atatttctcc gtggcttcaa ttgcttcgtt gaaataagaa ccggctatgt tcagtgcggc
      841 gagcttggcg gcggcaagat agtcgtcggg gtatttctcc tgtatattat agtagcaccc
      901 cgtggcgggg agaagctctc ccataccttc gaaactttgg gcctgcagat gcaaggcgat
      961 ggcggaactg tctttctctg tcatcagact actttctcct aaagcatcct gaaacttctg
     1021 taaagagagc agtagtccga tgtattgaat acgcacatat ttgttttccg gattcagatc
     1081 gagtgcctgt tcataatatt tcagtgcctg ttggtatttg gccaatgaac ggcagcattc
     1141 ggctgcttcg atatatgcac gggtattggc agtgtcattg gttatgattt cctgataagt
     1201 ggaaagtgct tctgtattca tcccaagtcc ccgttgtgct ttaccttttt gcaagagtag
     1261 gggaattgtc ggcttttctt tggcaatgag agtgagagct gcctcgtaat cgtagtttgc
     1321 tattgcttcc tgaacatgat tgatgcgctg cgccatcacc agggtggtgg tacaaaggaa
     1381 ggcgaggaga ataatccgtt tcataaatat ttattttagt gtgtcgtaac aaagacgcaa
     1441 gatgctaaaa aatatcgtat ttacgaatta ttcgtagcct ttttggaata gattaacgga
     1501 atgataagag aagataacat aatgataagt gcggatattg catctaaaac agcaatatcc
     1561 gcacctaata ttttgtcccg gcattccgaa tggaagcctg acaggggcac cttgtcccta
     1621 cattaagaat cctaacagga taccggcagc aacagccgaa ccgattacac ctgctacgtt
     1681 cggacccata gcgtgcatca gcaagtagtt ggttggatca tattccagac cgacaacttg
     1741 tgagatacgt gcagagtcgg gaacggcaga tacacctgca ttaccgatca acggattgat
     1801 cttattgccc ttcttgagga agaggttgaa gatcttaacg aagatcacac ctgatgcggt
     1861 agcaatgata aatgacagtg caccgagggc aaagatcttg atggagtcga gtgtcaggaa
     1921 ctcggaagcc tgagtagagg cacctactgt caaacctaac aggatagtga taacgtcaat
     1981 cagcggaccg ctggctgtgt tagccagacg acgggttaca ccactttctt tcaacaggtt
     2041 accgaagaac agcataccca gcagaggcag accggaagga accaggaagc aggtcagcaa
     2101 cagaccgata atcgggaaaa tcactttctc tgtatgagaa acggcacgtg gcggtttcat
     2161 acggataacg cgttcgtgtt tggtggtgag cagacgcatg ataggcggct gtatcaccgg
     2221 aactaacgcc atataggagt aggcggatac cgcaatggct cccattaagt taggtgccag
     2281 cttggacgaa aggaagatag ccgtcggacc atctgctcca ccgatgatac cgatagcacc
     2341 ggcctgcatc gggtcaaatc ccatttccaa tgcgatcatg tatgcaccga agataccaaa
     2401 ctgggcagcc gcaccgatca gcatcagctt cggattggag attagcgccg agaagtctgt
     2461 catggcaccg atacctaaga agatgagcgg tggataccag ccggacgtta ctccctgata
     2521 caatatgttc aatacagaac cttcttcata tataccgact tttagtccgg cgtccatatt
     2581 gaaaggtata ttaccgatca gaataccgaa tccgatagga attaacaaca tcggctcgaa
     2641 ctctttggct acagctaagt aaataaagcc taaaccgata atgatcatag caatatgtcc
     2701 acctgtcgcg ttggcaaatc ccgtgtaggt ccagaaatcg gcaaggttat ttcctaaaaa
     2761 gttaataaaa tctcccatat tattcaataa ttacgaggtc attaccttca agaacagaat
     2821 ctcccttgtt gacattgatg gcagtcactt taccgtcttt gtctgcattg atattgtttt
     2881 ccatcttcat ggcttccaat ataatgatag tctgtcctct tttcactgta tcacctacat
     2941 ttactttgat gtcaaggata acgcctggca gtggggactt aacgcctgat ttgccggtag
     3001 aaggagcagc cggttttact accggtgtgg taggagcagc cggtgagtta ggcatagggc
     3061 gtactactgc cggtttggga gtagctttcg gttgtttctc catttctact ttgtaatgcg
     3121 taccgttcac ttctacatga gcgatattat cttcaatatc tccgatggtt actttgtatg
     3181 agttaccgtt gattttatat ttatattctt tcatcgtttt atctttttag ggaatgattt
     3241 actttctgtt aggattttca cgcaaggtgt aaatcttcga actccacggt gaataactgc
     3301 gcttcacacg agtgatggtc agcaccgttt cttctacgtc gtgtacctca tcctgcattt
     3361 cgtgtaatgc cattgaaata gcagcataaa cttcacccgg agcctgtgaa agctctttcg
     3421 cttcgacttt atcgatgcct ttagccttca tcgcattgcg tttgctcagg ttgacagcaa
     3481 ctttacctac caccttgaag gcaatgaaga gaagaatcaa tccgcagaat actacgctca
     3541 tggctgaaat agacataccg ataccgactg agtcatgttc ttcgaacttt tccatcttgg
     3601 cattactgtc aagggttttg ttgttcgtgc tcggggttac gtatttgtct ttgcttccgc
     3661 cttttacttc ccagtctgct gctccgtcgc ttatgcgtgc ataagactgg ttgggaccta
     3721 aagttcctgc tggtatgaca acttgatcaa gtagctttct gcctgaatca aaaagaccga
     3781 cccaattggc tgtttcggga ttcagtttga agctggtatg gaaggttcca cgattaggtt
     3841 cgccatctgc ccaaaataac gcatgttggc gtggctttac taatgtaagt atgtcacctt
     3901 ttgggataaa ataggttact gtatcgcccg gctggctgct tactttcaat aaacaagctg
     3961 ctaagtctgc gctaccgtat gatttgttga atatttcaat ccatgcactg tgcaagccgt
     4021 agtcatcctg aaagttgttt tgattgtcta tcaggacttc attcagcaat agcttattgt
     4081 tcgacttttg ctctccgcag gaagtcaatc caatcagcaa cagcagagaa aggaatattc
     4141 cgattttggt tttgttcata atcgttcttg ttttaatgtg aaaagttgga ttacaacgga
     4201 atattaccat gtttcttcgc cggattagac agtttcttag tctgcaactg ctgcaaagca
     4261 cggatcacgc ggaaacgtgt gttacggggt tcgatgacat catcgatgta accatactta
     4321 gctgcattat aagggttggc aaacagtttt gtatattctg cttctttttc ggcaaggaac
     4381 tgagccggat tttcctggtc tttggcttca cgcgcgtaca atacttctac tgcacctgca
     4441 ccacccatta cagcgatttc agctgttggc caagcatagt tcatgtcacc acgaagttgt
     4501 ttacaactca tcacgatgtg agaaccaccg taagatttac gcaatgtgat tgttacttta
     4561 ggtacagtag cttcaccgta agcatacagc agtttggcac catgaaggat gacgccattg
     4621 tattcctgac ctgttcccgg aaggaatccc ggtacgtcta ccaacgacac gatagggata
     4681 ttgaaagcat cgcagaaacg aacgaaacgt gcgcctttgc gagatgcgtt gctgtcgagt
     4741 acaccggcaa ggaatttagg ctgattggct acaataccta cagactgacc gttgaaacgg
     4801 gcaaaaccga taatgatatt cttggcatag tctttctgga tttccaggaa ttcgccgttg
     4861 tctacgatag cgctgataac ctcgtacata tcatacggtt tgttggggct gtcggggata
     4921 atatcgttca gagaatcttc cagacggtcg atcggatctg tgcaatccac gtatggagct
     4981 tcttcgaggt tgttttgagg aatatagctc agaagtgtgc ggatcaatgc cagaccttct
     5041 tcttctgttt tggcagtgaa atgagtaaca cccgatttgg tagagtgaac gcttgctccg
     5101 ccgaggtttt cctggcttac gtcttcaccg gttacagttt tcactacttt cggacctgta
     5161 aggaacatat aagaagtacc ttccatcatc agtgtgaagt ctgtcagtgc cggagaataa
     5221 acagcaccgc cggcacaagg cccgaagata ccggaaatct gcggaatgac acccgaagcg
     5281 aggatattgc gctggaagat ttctgcgtaa cctgccaaag cgttaatacc ttcctggata
     5341 cgtgcaccgc ccgagtcatt gataccgata caaggagcac ccatcttcat tgcctgatcc
     5401 ataatcttac agatcttcag tgacattgtt tccgacagtg aacctgcagt aacggtaaag
     5461 tcctgtgcaa aaagatatac gagacgacct tcgatagtac cgcaaccggt tactacacca
     5521 tcacccggat agtgcttttt ctccatgccg aagttcgtgc atctgtgctc aacgaacatg
     5581 tccatttctt cgaagctacc ttcatccaac agcatggcta tacgctcacg cgctgtgtat
     5641 ttcccttttt catgttgctt cgcaattgct ttttcgccgc ctccgatgcg tgcaacggca
     5701 cggcgttcaa taagctcttt aattttttca agttgattac tcatgagttc ttgttgtttt
     5761 tttagagttt atgattagtg ttcgcagagt tctgtcagca cacccagtgt tgatttcggg
     5821 tgaaggaaag cgatgttcag accttcggca cctttgcggg gagccttgtc aatcagacgg
     5881 atttctttgc tttctgcttc tgccaaagca ttagctacgc catcttctac ggcaaatgct
     5941 acgtgatgaa cacctgcacc tttgttttca ataaatttag caatggtgct ttcggggcaa
     6001 gtcggctcca acaattcgat ttttgtttca cctaccttta aaaaagcggt tcttactttt
     6061 tgatcttcta ctgtttcgat gttgtaacat ttcagaccca atacgttttc gtagtaagga
     6121 agggcttctt cgatgctttt tacagcaatg cccagatgct caatgtgtga aatcttcata
     6181 actatatttt tttatatggt ttaattatgt gcttatatgg cataaaacag cacaaagaaa
     6241 gacatttctt gtctaataaa gaaatatttc tgcatttaat tattggggaa taaagcataa
     6301 aaaatgctcc ggatgggtga caaagacggg ttttgtaatc ttgagattac atttagacat
     6361 aaaacttgac cagaagatta ttcagccatg gccagctgat acggaaccag cggcgggtac
     6421 tgctttgttt gcctccgaaa cggagtacga aatcacgata accatgcttg cggaagggaa
     6481 gtcctacatc catgaactcc atgtgacgga atccccgttc atgggcatct tcaagtgctt
     6541 tccatactgc cagtatgccg ggtgactgca gtgcataggt ctttcgcatt cctcctgaaa
     6601 accagataaa agcattttcg ccggaataga tgcagacgga gccgccgata atcttttcct
     6661 tgtattttac gatgaatatt tttgcctgtt ttcctctgat aagcatgctg ttcatgtggc
     6721 ggaaaaagtc attggcaggg aaatatctcc gtattcgtga agaataaact ttgtgcagca
     6781 tccgcgagaa ttccttaatc tcttccaccg tatgggcttc tactactttg gctccgtttt
     6841 tgagcccttt ccggatctga cg
//
