LOCUS       c00015_gnlPro..        14567 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JHMJFLOD_15.
ACCESSION   c00015_gnlPro..
VERSION     c00015_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-07 15:16:29
            Original ID  :: gnl|Prokka|JHMJFLOD_15
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14567
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14567
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[88:4567]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      89..4567
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /neighbourhood="10000"
                     /product="Glycine_cleavage"
                     /protocluster_number="1"
     cand_cluster    1..14567
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T,
                     GDC-P, SoxG]) and GCV_H and GCV_T_C)"
                     /kind="single"
                     /product="Glycine_cleavage"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14567
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Glycine_cleavage"
                     /region_number="1"
                     /rules="(minimum(2, [Aminotran_5, GCV_H, GCV_T, GDC-P,
                     SoxG]) and GCV_H and GCV_T_C)"
                     /tool="gutsmash"
     CDS             complement(89..2872)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GDC-P"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Beta_elim_lyase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_1"
                     /sec_met_domain="Beta_elim_lyase (E-value: 8e-10, bitscore:
                     30.4, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="GDC-P (E-value: 1.9e-173, bitscore: 569.2,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDSLGYRTLDELIADIVPADIRMKAPLDLPAAKSETEALEELRS
                     ILRKNKLLKTFIGQGYYGTITPSVILRNVLENPGWYTAYTPYQPEIAQGRLEMLMNFQT
                     MVSSLTGLPVANASLLDEGTAAAEAVTMCRNARPKANTFFVADTCHPQTISVIRTRAAF
                     QGVNIIVGDCSSFDPASIGADLAGVLVQYPDTLGRICDYTDFFSRVHATGALCVVAADL
                     MALTVIREPGAFGADICIGNTQRFGIPMGFGGPHAAYMSCTDALKRRMPGRLIGMSIDT
                     LGRPAYRLALQTREQHIRRDKATSNICTAQVLLAVLAAFYAVYHGQEGLKRIGTEIHLK
                     TKNLYKALTEAGIAIENKNFFDTLLLSVPGQADAMVQKALEAGYNIRRVDADHAAISLD
                     ETATCADIAALASALAGAETSATCDCDAPAWDPVHTRQTPFCTEKAFNSYHSETEMMRY
                     IRRLESRDLALNEAMIPLGSCTMKLNAASEMIPITWPEANSLHPFVPADQSEGIREMLS
                     VLSDRLAKITGFAAVSLQPNAGAAGEYAGLLAIRRYQKHAGEGHRNVCLIPTSAHGTNP
                     ASSAMAGLKVVPVKCDERGNIDMADLKFQAEAHKDNLSCIMVTYPSTHGVYEQTIKELC
                     DIVHANGGQVYMDGANMNAQVGLTCPGCIGADVCHLNLHKTFAMPHGGGGPGIGPIGVA
                     EHLVPFLPGHLTLGHEEGAVASAAWGSASIAAICWMYLSMMGPDGLREATEMAILNANY
                     IAKKLGHLFPVLYSGNKGLVAHECILDPRQLTHDAGLTVDDIAKRLMDYGFHGPTMSFP
                     VPGTLMVEPTESEPKKELDRFIEAMERIHAEITAIINGTADKEDNVLKNSPHTAEMVSA
                     DEWRHPYSRSEAAYPVSGLLIHKFWPYVGRVDNVYGDRNLVCTCDTVEEFSKAVEL"
     CDS             complement(3031..3411)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_H"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_2"
                     /sec_met_domain="GCV_H (E-value: 1.1e-47, bitscore: 153.0,
                     seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHDVPENLLYSKDHEWIEIDGDIGTIGISDHAQAELSDVVFVDLP
                     EVGATVAAGDPVAVVESVKAASDVYTPVSGEILEVNEELSNDPSLINSDPYGAGWLYKI
                     RLDVPTETEDMMNATDYEEYCS"
     CDS             complement(3482..4567)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Glycine_cleavage: GCV_T_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg15_3"
                     /sec_met_domain="GCV_T (E-value: 1.6e-87, bitscore: 285.1,
                     seeds: 72, tool: rule-based-clusters)"
                     /sec_met_domain="GCV_T_C (E-value: 2e-23, bitscore: 74.2,
                     seeds: 348, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTDVKSTPLAAKHVELGARMVPFAGWNMPVQYTGILDEHKAVR
                     ETCGIFDISHMGQFTVAGGSAAAWLNSMLTNDINKLNVGQGQYSVMLNDRAGVIDDLIL
                     YRMEPETFFVVVNASKIDEDFAWLSAHQPAGVTLENHSDEYVGLAVQGPECGEVFSRVI
                     PGVELPPRNGISRITAEGTDLIICRTGYTGEDGFEFFCPAKEGVKWFEAFLGAGAKPCG
                     LGARDSLRLEMCYPLNGSDLSPDKTPLEAGLGFFCALDTDFIGSDILREQKANGLSRRL
                     AAIEYTGKGAPPRAHYAVHVPGGEAIGELTSGVLSPSLMKGIALAYLPAAHAKVGTELE
                     IDVRGRKFPAVVVKKPFYKKG"
     CDS             complement(4643..5764)
                     /locus_tag="ctg15_4"
                     /transl_table=11
                     /translation="MLQAGIVGLPNVGKSTLFNAVTRTRKAQAANYPFCTIDPNVGMVT
                     VPDPRLQVLSDMSGSEKIIPTLIEFVDIAGLVKGASEGAGLGNQFLANIREVDAIVQVV
                     RCFDNDDIIHELGSVDPLRDIDIINSELILADIATMEKRLSSRERKARSGDKEAKAEVA
                     LITKLLPHLNEGNPALTLEPQLDDDERKLLHSFQLLSDKKSIFACNVNEDELADAISNP
                     DAHPYVSQVKKYVAEHHNAEAIVISARIEEELIDVSEEESREFLESLGVKDSGVSDLIR
                     AVYHLLGLRTYLTTGIKETRAWTIPSGAKAPQAAGVIHTDFERGFIAAEVVHYDDLVSC
                     GGKAGAREHGKLRIEGKEYVVKDGDVIEFRFNV"
     CDS             complement(5823..6746)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S11"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg15_5"
                     /sec_met_domain="Peptidase_S11 (E-value: 2e-55, bitscore:
                     179.8, seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLFALLAGFSLCLSSTSCQSYGDSSDYIPLATPVPPQLSQPVSH
                     ALPRPANFPTRPVAIPSSAPRTPRCASACVMDALTGNVLFSHNGLQRRQVASTQKLVTA
                     MVVMEHGSLDKKVVIQPSDTKADPTKLGFRAGEVYSRRELLNAMMIRSFNDVALALARD
                     TAGSVPRFAQLMNAKARQMGMYNSRFANPNGLPADQYSTAIDMARCAYYVYRNPELRNI
                     ICKRQYAFTRANGRTLLLRNTNKLLTQNPWVTGMKTGYTNAAGRCLVSSAGVNGRHVIV
                     VVLGCHPSRIWTESENLIRWALGSAA"
     CDS             complement(7308..8435)
                     /locus_tag="ctg15_6"
                     /transl_table=11
                     /translation="MTPREAAIALNLIPGLGPVKIMRLLQVFASPELILESPSSLLMEI
                     PGVGAQLACRISSWRSIVNPYRELELADNAGAAVTTVFDDSYPSALRALPDPPIVLYSW
                     GNWNGTDAERSIAVVGSRMATHYGRLCARNISHDLAEAGITVISGLARGVDTEAHTGAM
                     DAEGRTIAVIGAGLNKLYPRENRNLAQRIADGHGAVVSEFPMDLSPSRTTFPMRNRIVS
                     GWSRATLVVEASGRSGALITARTAAEQGREVFCIPGPVDRHSSDGCHALIRDGAILATG
                     ASDILQDMNWAVPEQGLPLFSPCSPAGASTPPLPTLEEKEILHAIRLGFNTIDTLCTSL
                     GKAAHTITPLLARMQIAGQITPDAGGYFSINSREL"
     CDS             complement(8432..9487)
                     /locus_tag="ctg15_7"
                     /transl_table=11
                     /translation="MELGSGLSSRGVENIVVSGGGRLVPRLEKEGSRHILMPIGKKSIS
                     TLFRIGALRALLQAVRPDILHLHSRVPAWAGYLAWKKLPPEDRPGLVTSVHGFYSVNRY
                     SAIMSRGERVIAVSNCIRDYILDHYPSTPPDHIRIIPNAISPDQYHPAYSPSREWLTGW
                     FMSYPELKGKFTLCLPGRITRLKGHLDLIPVVRQLLEQGIPAHAVIVGEAKKGKEEYKN
                     EVLRAIERSGVSQSFTWTGHRQDLREILSTCSVTLSLTKSPEAFGKSTLEALALSKPVA
                     GYAHGGVKEQLDAFLPEGNVAVGDTAAMADLLARWHAQPPPLPRQIPSPYNMQDMIQAH
                     LDVYQELTPYS"
     CDS             complement(9541..10671)
                     /locus_tag="ctg15_8"
                     /transl_table=11
                     /translation="MRAFFRTGHPAAGKTKLPGHGAQGIFNNRGIRSQHAGIMNKSMPP
                     TKNFLLSGGNWIACTPPPLHNAAYMNIRILSDGKQGHLNQSLGLAQALISKAGGTVETV
                     DLQGLSLLGKIRKVVTGSDIPRPDMFISAGHATHIPLICARHHFKTRAVLCMKPTLPCS
                     FFDLCLIPRHDLDSGRDYTDTDIFPTQGALHPMRPDPSVPKDTTLILIGGPSKDFDWDD
                     ESMLNQLASISIHTPGHLVLTTSRRTPDGFAEKIRTAVPELTVVPVEETRPGWVARHLA
                     HASAAWVSQDSVSMVYEALGSGAPVGILSVPRRHGSRKSRILSGLETLEKEGMVTGYSD
                     WKKQNFRLTAPGSPLLEADRAADYILSRFFPQLRAL"
     CDS             10717..11628
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_16"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:4Fe-4S dicluster domain (Score: 66.9; E-value:
                     8e-21)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg15_9"
                     /sec_met_domain="Fer4_16 (E-value: 8.1e-21, bitscore: 66.9,
                     seeds: 227, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEWMARSPERRTDPAEVLPGCRSVICLSYDYDSPGRRPEGEGSIC
                     LYAHGKDYHGILEEKLADLQELLSIYGGKQRGYVDSGPVMERDHAEACGLGWRGKSGLI
                     VRRKGGSRFFIATLLTTLELEPDAPVSNGCGSCRRCAALCPTGAIMENGQVDAGRCLSY
                     WTIEHRGAIPEEIRPLIGTRLYGCDTCVTVCPWNGKPLPDVDERFRMSRLLASIPLRGL
                     LSLDAGGFAALFRNSPLKRLKREGLLRNGCVVLGNAGTPDDIDFLKALYGESPLVEEHA
                     SWAVERILRRHGRHASSSGARD"
     CDS             11747..12124
                     /locus_tag="ctg15_10"
                     /transl_table=11
                     /translation="MARLFGTEIPNEKRIEASLPYIYGIGRSTSKRILEQAGINPDIRT
                     GQLTDEQLTKIVQVITTDGILIEGDLRREKQSILKRLTSINCYRGQRHRRGLPVRGQRT
                     RTNARTRKGKKKTVGAQAKKK"
     CDS             12158..12709
                     /locus_tag="ctg15_11"
                     /transl_table=11
                     /translation="MASEEITNETAEQPVEAAASAPVAETPAAAVSAPEEIKKPEPRKD
                     IFAELGLGGDDDKPKILKAKGSKNVSTGVVHVSSTFNNTVVTVTDQRGNVIGWSSAGKM
                     GFKGSRKSTAYAGQVVCQDACRQAMGHGLREVEVRVKGPGSGRESAVRAVQTIGIEITS
                     IKDVTPIPHNGCRPPKARRV"
     CDS             12745..13356
                     /locus_tag="ctg15_12"
                     /transl_table=11
                     /translation="MARYTGPRDKVSRRFGVALFGSTKALEKRPFPPGQHGMRAGRKKK
                     SDYGVMLAEKQKLRFQYGVLEGQFRKYYAEAARRRGITGDILLQLLELRLDNVVYRLGF
                     SNTRAGARQLVSHGHITVNGKKTNIASYSCRPGDVIAVGGKASSQQLVTRFLDLTQATV
                     VPDWLECDRDKLTGKIARVPSKEEIAPIVNEQLIVEFYSR"
     CDS             13487..14254
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg15_13"
                     /sec_met_domain="HAD (E-value: 1e-35, bitscore: 115.8,
                     seeds: 107, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDDWKKRGAALFDMDGTLLPWDTQYIFSCFVVRRHPWRRLLIFL
                     FLACIPLYILRIWDENRMKRAYLMYLWGLPAETVREYGRKFAEMAQEWIYPELKERLAG
                     YRKKGYLCLMVSASPSFYVKPLGELLGFDEVLGTDVLLEERMPAMPELPNGNNKGAVKV
                     ERLRERNVLPEHGVLENAVAYSDSAADLPMLLSCRRRVLVNPSPALKEDRLLVGAECLY
                     PARPWKGRFGKIWRIGFFVMGLVDLNNVKSMTC"
ORIGIN
        1 cttcggatta gaaatccgat tcttgaacat aagaaaaagg ctgctccaaa tgaatggaac
       61 agcctttttg aaaggaagga tgagattttt ataactctac ggccttggag aattcctcca
      121 ccgtgtcgca ggtgcagacc agattgcggt ctccgtacac attatccacc cggcctacat
      181 acggccagaa tttgtgaata aggagaccag agaccggata agccgcttca ctgcgggagt
      241 agggatgccg ccattcgtcg gcagagacca tttctgcggt atggggcgag tttttcagga
      301 cgttgtcttc cttgtctgcc gtaccgttga taatggccgt gatttccgca tgaatgcgtt
      361 ccatggcttc aatgaagcgg tccagttctt ttttgggttc cgattccgtc ggctccacca
      421 tcagggtgcc cggaacgggg aaggacatgg tggggccgtg gaagccgtag tccatgagcc
      481 ttttggcaat gtcatccacc gtgaggccgg cgtcatgagt gagctggcgc ggatccagaa
      541 tgcattcatg cgccaccagc cccttgttgc cggagtagag aaccgggaag agatgtccga
      601 gtttcttggc aatgtagttg gcgttaagga tggccatttc cgtggcttcc ctgaggccgt
      661 ccggccccat catggagagg tacatccagc agatggcggc gatggaggcg cttccccacg
      721 ccgcagacgc tacggcccct tcttcatggc ccagcgtgag gtgcccgggc aggaagggta
      781 cgaggtgttc cgctacgccg atgggcccga tgccgggacc gccgccgccg tgcggcatgg
      841 caaaggtttt atgcaggttc aggtggcaga cgtccgcgcc aatgcagccg gggcaagtca
      901 gacctacctg ggcattcatg ttggctccat ccatgtacac ctggccgcca ttggcatgga
      961 cgatgtcgca gagttccttg attgtctgtt catatacccc gtgcgtggag gggtacgtga
     1021 ccatgatgca ggaaagattg tccttatggg cttccgcctg gaatttcagg tctgccatgt
     1081 cgatgttgcc tctttcgtcg catttgacgg gcaccacctt gaggccggcc atggcggagg
     1141 atgcgggatt tgttccgtgg gcggaggtgg gaatgaggca gacattgcgg tggccttctc
     1201 cggcgtgctt ctggtagcgg cggatggcca gtagcccggc atattcccct gcggcgcccg
     1261 cgttgggctg gagggatacg gcggcaaagc cggtgatttt cgccagacgg tcggacagga
     1321 cggagagcat ttcccggatg ccttccgact ggtccgccgg aacaaaggga tgcagggagt
     1381 tggcttccgg ccacgtgatg ggaatcattt cagaggcggc gttcagcttc atcgtgcagg
     1441 agcccagagg gatcatggct tcatttagag ccaggtcccg ggattccagg cggcggatgt
     1501 agcgcatcat ttccgtttcg gaatggtagg agttgaaagc cttttccgtg cagaaaggcg
     1561 tctggcgcgt gtggacggga tcccaggcag gagcgtcgca atcgcaggtg gcggatgttt
     1621 ccgcacctgc aagggcggag gccagtgccg ctatatccgc acaggttgcg gtttcatcca
     1681 gagagatagc tgcgtggtcg gcatccaccc tgcggatgtt atacccggct tccagggctt
     1741 tttgcaccat ggcgtccgct tgtccgggaa cggacagcag cagggtgtca aagaagtttt
     1801 tgttttcaat ggcaatgccg gcttccgtga gcgccttgta caggtttttg gttttcaagt
     1861 ggatttccgt gccgatgcgt ttgaggcctt cctggccgtg gtatacggcg taaaaggcgg
     1921 caagcacggc caggagcacc tgggcggtgc agatgttgga ggtcgccttg tcgcggcgaa
     1981 tatgctgttc cctcgtttgc agggccaggc ggtaggccgg gcggcccagg gtatctatgg
     2041 acatgccgat aaggcggccg ggcatgcggc gtttgagagc gtccgtgcag gacatgtagg
     2101 cggcatgggg gccgccgaag cccattggga tgccgaagcg ctgcgtgttg ccgatgcaga
     2161 tatcggctcc gaaggcgccg ggttcccgga tgacggtaag ggccatgaga tccgccgcca
     2221 cgacgcagag cgcgcccgtg gcatgcacgc gggaaaagaa gtccgtgtag tcgcagatgc
     2281 ggccgagcgt gtccggatat tggacaagca ctccggccag atccgcaccg atggatgcgg
     2341 ggtcaaagga ggagcaatct cccacgatga tgttaacgcc ctggaaggcg gcgcgggtac
     2401 ggatgacgct gatggtctgt gggtggcagg tgtccgccac aaagaaggtg tttgctttgg
     2461 ggcgcgcatt ccggcacatg gtgacggctt ctgctgctgc ggtgccttca tccagcaggg
     2521 aggcgttcgc taccggcagc cctgtcaggg aagagaccat ggtctggaaa ttcatgagca
     2581 tttccagccg tccctgggcg atttccggtt gataaggggt gtaggccgtg taccagccgg
     2641 ggttctccag tacattgcgg aggatgacgg agggagtgat ggtgccgtaa tagccctggc
     2701 caatgaaggt tttcaggagc ttgtttttcc gcaggatgga acggagttcc tccagggctt
     2761 ccgtttccga tttggctgcg ggcaggtcca gcggggcctt catgcggata tctgcgggga
     2821 cgatgtccgc aatgagttcg tcaagcgtcc ggtagccgag gctgtcaagc atttcccggc
     2881 gttcttcccc ctgggggccg atgtgccggc tggcaaaatc tgagtgggta ttcatgtggt
     2941 atctctggct ggtaatagcg tccggccgcg gaacgggcca aacaaaatgc cccgggatgg
     3001 aatcaccggg gcgggggagg gaagaatggt tcaggagcag tattcctcgt aatccgtggc
     3061 gttcatcata tcttccgttt ccgtgggaac gtccaggcgg attttgtaca gccagcctgc
     3121 gccgtaaggg tcggagttaa tgagggacgg atcattggaa agctcttcgt tcacttccag
     3181 gatttctcct gaaacggggg tgtacacgtc gctggcggct ttgacagatt ccacgacagc
     3241 gacagggtcg ccggctgcga cggtggcgcc tacttcggga aggtctacaa agacgacatc
     3301 ggagagttcg gcctgggcat ggtcggaaat gccgatggtg ccgatgtccc cgtcaatttc
     3361 aatccattcg tgatctttgg aatacagcag attttctggt acgtcgtgca taagatgtaa
     3421 ttgtttgaag tgagagtgta gtaaaatgag gtgtttgtca gtttattttt gcgccgtagt
     3481 gtcagccttt tttataaaag ggttttttta cgaccacggc tgggaatttc cttcccctta
     3541 cgtcaatttc cagctccgtg ccgaccttgg catgggcggc aggcaggtag gccagggcaa
     3601 tgcccttcat cagcgaagga gagagcacgc cgctggtaag ttctccgatg gcttctccgc
     3661 cggggacgtg cacggcatag tgggcgcggg gaggagctcc cttgccggtg tattcaatag
     3721 cggccagccg acggctgagg ccgttggctt tttgttcccg gagaatatcg gaaccgatga
     3781 agtccgtatc cagcgcgcag aagaatccga gcccggcttc cagaggcgtt ttgtccggag
     3841 agagatcgga gccgttcaga ggatagcaca tttccagacg caggctgtcc cgggcgccca
     3901 ggccgcaggg tttggctcct gctccaagaa aggcttcaaa ccatttgacg ccttccttag
     3961 ccgggcagaa gaattcaaaa ccatcttccc cggtatagcc ggtgcggcag ataatgagat
     4021 ccgtcccttc cgccgtgatg cgggagattc cattgcgggg tgggagttcc acgccgggga
     4081 tgacgcggga gaatacttct ccgcattcgg gaccttgaac agccagcccc acgtattcgt
     4141 cggagtggtt ttccagggtt acgcctgcag gttgatgggc ggaaagccat gcgaagtctt
     4201 catcaatctt ggaggcgttc accactacga agaaggtttc cggttccatc cggtacagga
     4261 tgaggtcgtc aatgactccg gccctgtcat tgagcatgac ggagtattgc ccctgcccta
     4321 cattcagttt gttaatgtca ttggtcagca tggagttcag ccatgccgca gcggaaccgc
     4381 cggctaccgt gaactgcccc atgtgggaga tgtcaaagat gccgcaggtt tcgcgcactg
     4441 ctttgtgttc gtccagaatg ccggtgtact gcaccggcat attccagccg gcgaaaggaa
     4501 ccattctggc tcccagttca acgtgtttag ctgccagggg ggtggatttg acgtctgtat
     4561 cagtcatgag gcgatgtgaa ggttgtgagc aatctgcccc ttatatcagt aaaagtcaat
     4621 ggaattccgg taacgcttcc gtctagacat tgaagcggaa ttcgatgacg tccccgtctt
     4681 tgacgacata ttcttttcct tcgatgcgca gcttgccgtg ttccctcgct ccggccttgc
     4741 cgccacagga aaccaggtcg tcgtagtgca ctacctctgc ggcgataaaa ccgcgttcaa
     4801 agtccgtgtg gataacgccg gccgcctgag gtgcttttgc cccggacgga atggtccagg
     4861 cccgcgtttc cttgattccc gtggtgaggt aggtgcgcag gcccagaagg tggtacacgg
     4921 cgcggataag gtcggaaacg ccggaatcct tcacacccag ggattccagg aattcgcggg
     4981 attcttcctc cgagacgtcg atgagttcct cttcaatccg ggcggagatg acaatggctt
     5041 ccgcgttatg gtgttccgct acgtattttt tcacctggga gacgtaggga tgggcgtccg
     5101 ggttggagat ggcgtccgcc agttcgtctt cattgacatt gcaggcgaaa atgctttttt
     5161 tatccgaaag cagctggaag gaatggagca gcttgcgttc gtcgtcgtcc agctgcggtt
     5221 caagggtgag ggcgggattg ccttcgttca ggtggggcag gagtttggtg atgagggcca
     5281 cttcggcctt ggcttccttg tcgccgctgc gtgccttgcg ttcgcgggaa gagagtctct
     5341 tttccatggt ggcgatatcc gccagaatga gttccgagtt gatgatgtca atgtcgcgca
     5401 gaggatccac ggaaccgagt tcatggataa tatcatcatt gtcaaagcag cggactacct
     5461 gcacgatggc gtccacttca cggatgttcg ccagaaactg gttgcccagg ccggctcctt
     5521 ccgaggctcc cttgaccaga ccggcaatat ccacgaattc aataagcgtg gggatgattt
     5581 tttcagaacc ggacatgtcg gaaagaacct gcaggcgggg atccgggact gttaccatac
     5641 ccacgttcgg gtcaatggtg cagaagggat agttggccgc ctgggccttg cgcgtccggg
     5701 tgaccgcatt gaataaagtg gatttgccga cgttggggag acctacaata cctgcctgta
     5761 acataggcag gactgatagc gggtcacgcc gtgaaagtca aataccaatt gccgacgggc
     5821 atttatgcgg cggatcccag agcccatctg atcaggtttt ccgattccgt ccagatacgg
     5881 gacggatggc agccgaggac gacgacgatg acatggcgcc cgttgacgcc ggctgaggaa
     5941 accaggcagc gtccggcggc gttcgtgtat ccggttttca ttccggtaac ccaggggttc
     6001 tgggtgagca gcttgttggt gtttctcagc agaagcgttc tgccgttggc gcgggtaaag
     6061 gcatattggc gtttgcagat aatattgcgc agttccgggt tgcggtacac gtaataggcg
     6121 cagcgggcca tgtcaatggc agtggaatat tgatccgccg ggaggccgtt gggattggcg
     6181 aagcgtgagt tgtacatgcc catctgccgg gctttggcat tcatcaactg ggcgaaacgg
     6241 ggaacggaac ccgccgtatc gcgggccaga gccagggcta cgtcgttgaa actgcggatc
     6301 atcatggcat tgagcagttc gcggcgtgaa tagacttccc ccgcccggaa tcccagtttg
     6361 gtggggtccg ccttggtatc ggaaggctgg atgaccactt ttttgtccag gctgccgtgt
     6421 tccatcacga ccatggccgt cacgagtttc tgcgtgctgg ctacctggcg gcgctggagg
     6481 ccgttgtggg aaaagagcac gttgccggta agggcgtcca tgacgcaggc gctggcgcag
     6541 cggggcgtgc gcggggcgct tgaggggatg gctacgggac gtgtggggaa attggccggt
     6601 cgggggaggg catgggaaac cggctgggag agttgtgggg gaacgggcgt tgcaaggggg
     6661 atgtagtcac ttgaatcccc gtacgattgg cagcttgtgg agctcaggca aagggagaat
     6721 cctgcaagaa gggcgaataa acgcatgtct tgttgctaca gtaagaagtt tcgttcatca
     6781 agcccaaact ccgcatttga aagagagccg gacgaaaaag gccgcggatc ggacaatccg
     6841 cggccttttt tctctattaa ctacctatgg aaccaaaaac caccctgaac ggattttgaa
     6901 ttgcttttcc catccgtcgg acagatcttg tgaaggatga gactccaggc aggagagatg
     6961 cgttcaaaat atgttcgtca acagttcttt ttaagaggtg ttgccgtatg cgctcgagcc
     7021 tgcgtccagt aaatatggca gagatttttt ccgaacatat tttgtttttc gcgggcatgt
     7081 aaattttgcc gcaggcattt aaaatgccgg ggatgtcctg ccgatatatt taatttttgg
     7141 aataaaatta ttgaaggaaa ggatttggcg actgttttaa gacgtttttt ttgcgtccgg
     7201 atggaaaggt ttttatacgg gagatggacg gcgatccctt ccggttccat ggtcagggag
     7261 aggaggcccg gacctggcgt tttccccggc ggaaaagcgg aatctgccta aagttccctg
     7321 ctgttaatgg agaaataccc tccggcgtcc ggagtaattt gccctgcaat ttgcattctg
     7381 gccaaaagcg gggtgatggt atgcgccgct tttcccagag aggtgcagag ggtatcaata
     7441 gtattgaaac ccagtctgat ggcgtggaga atctcctttt cttccaaagt gggaagcggt
     7501 ggggttgagg ctccggcagg ggagcatggc gagaagagag gcagtccctg ttccggaacg
     7561 gcccagttca tgtcctgcag aatatcggag gctccggtag ccaggatggc tccgtcccgg
     7621 atgagggcat ggcatccgtc ggaagaatgc cggtcaaccg gtccgggaat gcagaaaacc
     7681 tctcggccct gttcggccgc cgttcgggcc gtgatcaggg ccccgctgcg tccggacgcc
     7741 tccaccacca gcgtagcgcg gctccagccg ctcacgatgc ggttgcgcat gggaaaagtg
     7801 gtgcgggagg gggacaggtc cattgggaac tcggagacta ccgctccatg cccgtccgca
     7861 atgcgctgcg ccaagtttct gttttcccga ggatacagtt tgttgagacc tgccccgata
     7921 acggcgatgg tgcgcccctc cgcgtccatg gccccggtat gggcttccgt gtccacgccg
     7981 cgcgccagtc cggaaatgac agttattccg gcttccgcca ggtcatggga gatgtttctg
     8041 gcgcaaagcc tgccgtaatg ggtggccatc cgtgagccga cgacggcaat ggagcgttcg
     8101 gcatccgttc cgttccagtt tccccaggag tagaggacaa tgggcgggtc tgggagagca
     8161 cgcagggcgg atgggtagga gtcgtcaaaa accgtggtta ccgcggcccc cgcgttatcc
     8221 gccagttcca gttccctgta cgggttgacg atgctccgcc aagaggaaat gcggcaagcc
     8281 agctgcgccc ccacgccggg aatttccatc aacagggagg aaggggattc cagaatcagt
     8341 tccggagagg cgaatacctg caggagacgc atgattttga cagggcccag gcccggtatc
     8401 aggttcaggg ctatggctgc ttcccggggt gtcatgaata aggtgtcagt tcctggtaaa
     8461 cgtccagatg ggcttgaatc atatcctgca tattgtaagg ggaaggaatt tgccggggca
     8521 gggggggggg ctgggcatgc cagcgggcca gcaagtccgc catggcggcg gtatctccta
     8581 cggcgacgtt cccttcagga aggaaggcgt ccagctgttc cttgactccg ccgtgggcgt
     8641 atccggccac gggtttgctc agggcgagcg cctccagggt tgatttgccg aaggcttccg
     8701 ggcttttggt cagggagagg gtgacggaac atgtggaaag gatttccctc agatcctggc
     8761 gatggcctgt ccaggtgaag gactgggaga cgccggaacg ttctattgcc cgcaggacct
     8821 cgtttttata ttcttctttt cccttctttg cttctcctac aatgacggcg tgggccggga
     8881 ttccctgttc cagaagctgc ctgacgaccg gaatcagatc cagatgccct ttcaggcgcg
     8941 tgatgcggcc cggcaggcac agggtgaatt tccccttcag ttcaggatag gacatgaacc
     9001 agcccgtgag ccattcccgg gagggggagt aggccgggtg atattggtcc ggggaaatag
     9061 cattgggtat gattctgata tggtccggag gggtggacgg ataatggtca aggatgtagt
     9121 ccctgatgca gttggagacg gcgatcaccc gctctcctcg gctcatgatg gcggagtacc
     9181 ggttgacgga gtagaagccg tgaacgctgg tgacgaggcc ggggcggtct tcaggcggga
     9241 gctttttcca tgccaggtag cctgcccacg caggaacgcg ggaatggaga tgcaggatat
     9301 ccggcctgac ggcctgaagc agggcgcgga gggccccgat gcggaagaga gtggagatgc
     9361 tttttttgcc tatcggcatc aggatgtggc gggagccttc cttttccaga cggggcacca
     9421 ggcgtccgcc tccggaaacg acgatatttt ccacgccccg ggaagaaagg ccgctgccca
     9481 gttccataac gacttgttcc acgcctccgg attccatgga ggggacgaga tgtactattt
     9541 tcataaggcg cggagctgag ggaaaaatct ggagaggatg tagtctgctg cacggtccgc
     9601 ttccagaagc ggggaaccgg gagccgtcag gcggaagttc tgttttttcc agtcactgta
     9661 tccagtaacc atgccttcct tttcaagtgt ctccaggccg gacaggatgc gggatttgcg
     9721 gctgccgtgt cggcgcggta cggaaaggat gcctacaggc gcgccggagc caagagcctc
     9781 atataccatg gagacgctgt cctggctgac ccaggcggcg gaggcgtgcg ccagatgccg
     9841 ggctacccac cccggccggg tttcctccac gggaacgacg gttagttccg gaacggccgt
     9901 ccggattttt tccgcaaagc cgtccggcgt ccggcgcgag gtggttagaa caaggtgtcc
     9961 gggggtgtgg atgctgatgg acgcgagctg gttgagcatg ctttcgtcat cccagtcaaa
    10021 atctttgctg ggccctccta tgagaatcag tgtggtatcc tttggtacgg agggatccgg
    10081 cctcatgggg tggagagctc cctgggtggg gaagatatcc gtatccgtgt aatcgcggcc
    10141 ggaatccagg tcatggcggg gaataaggca gaggtcgaaa aaggagcagg gaagcgtggg
    10201 cttcatgcag aggacggccc gggttttgaa atggtgccgc gcgcagatga gcgggatatg
    10261 cgttgcatgt ccggcggaaa tgaacatatc cggccgtgga atgtcgctgc ctgtgacgac
    10321 cttccggatt ttccccaaaa gggaaagccc ctgcaggtcc accgtttcca cggttccccc
    10381 cgctttggag atcagagcct gcgccagccc cagggactga ttgaggtggc cctgtttccc
    10441 atcgctcaga atccggatgt tcatatatgc ggcattatga agcggcggcg gggtgcaggc
    10501 aatccaattt ccaccggaca gaagaaaatt cttggtggga ggcatgctct tgttcatgat
    10561 tccggcgtgc tgactccgga ttcctctgtt attaaagatt ccttgtgcgc cgtgtcccgg
    10621 cagcttggtt tttccggctg ccgggtggcc cgtgcggaaa aaagcccgca tgcggaaaaa
    10681 ttgtttcaat ggctggagcg cggatggcac gccgggatgg agtggatggc gcgttccccg
    10741 gagcggcgca cggatcctgc ggaagtgctt cccggatgcc gttccgtcat ttgcctgtcc
    10801 tatgattatg acagccccgg taggcgcccg gagggggagg gtagcatttg cctttacgcc
    10861 catggaaagg attaccacgg aattctggag gaaaaactgg cggatttgca ggagctgctt
    10921 tccatttacg gcgggaagca gagggggtat gtggactccg gccccgttat ggaacgggac
    10981 catgcggagg cctgcggcct gggctggcgc gggaaaagcg gtctgatcgt gcgcaggaaa
    11041 gggggctccc gcttttttat cgctaccctg ctgactacgc tggaactgga accggacgct
    11101 ccggtttcaa acggatgcgg cagttgccgc cgttgtgcgg ccctgtgtcc gacgggtgca
    11161 attatggaaa acggtcaggt tgatgccgga cgctgccttt cctattggac gattgaacac
    11221 cggggggcta ttccggaaga aatccgtccc ctgataggca cgcgcctgta cgggtgcgat
    11281 acctgcgtga cggtctgtcc ctggaacggt aagcctttgc cggacgttga cgaacgattc
    11341 cgcatgtccc gtctgctggc ttccattccc ctgcgcggtc ttctttccct ggatgccggc
    11401 ggttttgcgg ccctgttccg gaattccccg ttgaaaaggc tcaagaggga agggctgctg
    11461 cgtaacggct gcgttgtgct ggggaatgcg gggactccgg atgacattga ttttctgaag
    11521 gcgctttacg gggagtctcc tctggtggag gaacacgctt cctgggctgt ggagcgcatc
    11581 ctccgccgcc acgggcggca tgcatcttca agcggtgcaa gagattaaaa atagaaaaaa
    11641 tgatgttttg gtcttgtcaa aacctcaatt tatggtatcc atcttgcccc aagcaatagc
    11701 tctgcgcgag gcagagaaaa ataacagcta gcaaatccaa tccattatgg cacgcctttt
    11761 cggtacagaa atacccaacg agaagcgcat cgaggcttcc cttccgtata tttacggaat
    11821 tggtcgctcg acttctaaga gaatcctgga acaagcaggc atcaatcccg acatccgcac
    11881 gggacagctt accgacgaac agctcacgaa gattgttcaa gtaatcacca ccgacggcat
    11941 tttgattgaa ggtgaccttc gtcgtgaaaa gcaatccatt ctcaagcgtc tgacctccat
    12001 caactgctat cgtggtcagc gccaccgccg cggccttccg gtacgcggtc agcgtacccg
    12061 cacgaatgcc cgtacccgta aaggcaagaa gaagaccgtt ggcgcgcagg ccaagaagaa
    12121 gtaatccgcc aacctgaatt tttaatatag ctttactatg gctagcgaag aaatcaccaa
    12181 cgaaaccgcc gaacagcctg tggaagcggc agcttccgct cccgtcgctg aaactccggc
    12241 cgccgctgtt tccgctcctg aagaaatcaa gaagcccgaa ccccgcaagg atatctttgc
    12301 ggaacttggt ctgggcggcg atgatgacaa gcccaaaatc ctgaaggcca agggcagcaa
    12361 aaacgtttcc acgggcgtgg ttcacgtttc ctccacgttc aataacaccg tcgtaactgt
    12421 gactgaccag cgcggcaatg tcatcggctg gtcctccgcc ggcaagatgg gctttaaggg
    12481 ttcccgcaag agcacggcct atgccgggca ggtggtgtgc caggacgcct gccgccaggc
    12541 catgggtcac ggcttgcgtg aagtggaagt gcgcgtaaag gggcccggtt ccggtcgtga
    12601 atccgccgta cgtgccgtgc agacgatcgg tattgaaatc acctccatca aggacgtgac
    12661 ccccatcccc cacaacggct gccgtcctcc gaaggcccgc cgcgtctaat tgagaatctt
    12721 ttacctatat agatctaata tatcatggct cgttataccg gtccccgcga taaagtgtcc
    12781 cgccgttttg gcgttgccct tttcggttcc accaaggctc ttgaaaagcg ccccttccct
    12841 cccggccagc atggcatgcg cgccggccgc aagaagaaat ccgactatgg cgtgatgctt
    12901 gctgaaaaac agaaactgcg tttccagtac ggtgtgcttg aaggccagtt ccgcaagtat
    12961 tatgcagaag ccgcccgccg ccgcggcatt accggcgata ttctgcttca gctccttgag
    13021 cttcgtctgg acaatgttgt gtaccgcctc ggcttcagca atacccgtgc cggcgcccgt
    13081 cagcttgttt cccacggcca catcaccgtg aacggcaaga agacgaatat cgcgtcctac
    13141 tcctgccgtc cgggcgacgt cattgccgta ggcggcaagg cttcttccca gcagctggtt
    13201 acccgtttcc ttgacctgac tcaggctact gtggttcctg actggctgga atgcgaccgt
    13261 gacaagctca cgggcaagat tgcccgcgtg ccttccaagg aagagattgc tcccatcgtc
    13321 aacgagcagc tcatcgtgga attttactcc cgttaatctt atttccttct ggatttgctt
    13381 caaaaccccg gttgcctttc ggcggccggg gttttgggca ttcaggagga ggggcatgga
    13441 agagttgggt gttgagagtt aagggaagcg ggtataggat gaaagcatga cggacgattg
    13501 gaaaaaaaga ggcgcagcgc tgtttgatat ggacggcacg ctccttccct gggatacgca
    13561 atatattttt tcctgttttg tggtgaggcg ccatccttgg agacgcttgc tgatttttct
    13621 tttcctggcc tgtattccgc tctatatttt gagaatatgg gatgagaacc ggatgaagag
    13681 ggcttatctc atgtatttgt gggggcttcc cgctgaaacg gtgcgggaat atggacggaa
    13741 gtttgccgag atggcgcagg aatggattta tccggagctg aaggagcggc tggcagggta
    13801 tcggaagaag ggttatttgt gtctcatggt ttccgcttct ccatcatttt acgtgaagcc
    13861 cctgggcgaa ctgctgggat ttgacgaagt tctgggaacg gatgtgcttc tggaggaacg
    13921 catgccggca atgccggaac tgccgaacgg taataataag ggggcggtga aggtggagcg
    13981 tctgcgggag cggaatgtac tgccggaaca tggtgttctg gaaaacgccg ttgcctacag
    14041 cgacagtgcc gcggatctgc ccatgctgct ttcctgcagg cggagggttc tggtgaatcc
    14101 ttctcccgcc ctgaaagaag acaggcttct ggttggtgcg gagtgtctgt atccggccag
    14161 gccttggaag ggaaggtttg gcaagatatg gagaattgga ttttttgtca tggggctggt
    14221 ggatttaaat aatgtgaaat caatgacttg ctgatacatc aagagaaaat tctttacttt
    14281 tgtgacgaaa atgtttcact tttcttaaca agggggaaaa aatcattttt ctttccatgt
    14341 tagcaaatca acaattaata ccctaaccaa gtaatagtca tgcaaaccaa gaacatcatc
    14401 agtgttgcgg cagttgtgac atcctttgcc ggagctgctc ttgcgggtac tcccgtcaag
    14461 attgttgctc cgactccggt tcccgctcct gtggcgactt ccagcccgct gtccggcgat
    14521 atttacgccg gctacgcttc caattacacc tgccgcggca ttgtggc
//
