LOCUS       c00055_gnlPro..         4130 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NLOJDGCL_55.
ACCESSION   c00055_gnlPro..
VERSION     c00055_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-05 09:20:39
            Original ID  :: gnl|Prokka|NLOJDGCL_55
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4130
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4130
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2:3598]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3..3598
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..4130
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..4130
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(3..518)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg55_1"
                     /sec_met_domain="OAD_beta (E-value: 6.5e-17, bitscore:
                     50.1, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGIFSLSWQMVGMWGIAILLLYLGVAKQYEPLLMVPIAFGALIAN
                     IPDNGMLITQLNQQVISSNEQGEVTSTSLNNVGYLRVHVAPLQQTPAKVPANLTTPEAS
                     AQYLETMQQPMQVYPGSQLTVSKIKSVRESQEKAKADAARLGDDSLTVDPNLKDFQNVT
                     EDNGNEPVF"
     CDS             complement(636..1037)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 59.8; E-value:
                     5.7e-19)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg55_2"
                     /sec_met_domain="Biotin_lipoyl (E-value: 5.5e-20, bitscore:
                     59.8, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLRITVDGKVFDVSVELLDQVSSTTAAPAPAPVAAPAPAASAP
                     VAAPAPAPAPAPAPAAAGAGDVPSPLAGKVVSLDVAAGASVKAGDQILTLEAMKMNTII
                     YAPASGTLTAFCVNPGDTVQEGQALAKIG"
     CDS             complement(1112..1558)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg55_3"
                     /sec_met_domain="OAD_gamma (E-value: 1.3e-11, bitscore:
                     33.8, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLTTLAFAQGIANVMNNLNYQIVGIMVVMMCLGGLAVILTISGS
                     IAAAIQNRAKAKTAAPVAAPAAAPAAAGKPGMTPEMLAILSAAVDSAMTELTPEMVAVI
                     SAAVDAGLDGMSHRIVEIKQSPGSGYAAAGRAEIFASHRIRPSR"
     CDS             complement(1579..3144)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Vparvula"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg55_4"
                     /sec_met_domain="CT_Vparvula (E-value: 5.5e-217, bitscore:
                     709.8, seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAIDPKLIDDLNSRRKKVILSGGQEKIDKRHEKGEMTARDRMGYL
                     FEEGTFSEIGMHVRHNCHNFGMGKKEIPGDGVVSGFGLVDGRPVACAASDFLAQGGSLG
                     YMHAMKIADAQKYALKAGIPMVTVNDSGGARLQEGVAALSGYAQVFYNNVLASGVVPQI
                     SMILGPCAGGAAYSPALTDFIIMRNSGNAGMYITGPKVIEQVTYEKCTMDDIGSAAIHA
                     TVSGNVHFVADSDAHAMDILKRLLSFLPSNNTEEPPHKLDTPLDLSADEGMSDLIPGDN
                     RTPLDVQPIISRLVDNGDFLEVHKDFAKNVVVGFGRICGVVVGIIANQPNVKAGCLDID
                     SSDKAARFIRFCNAFNIPLVNLVDVPGFLPGKNQERGGIIRHGAKLIFAYSQATVPKVT
                     LIMRKAYGGAYIAMCCKDLGADAVFAWPGAEIAVMGAEGAVPVLYGRELKAVEDPAEKA
                     KRQGELLEEYREAFYNPYVAAGMGQITEVINPEETRAKIAFALRTLLNKKEVRPAKKHG
                     NIPL"
     CDS             complement(3176..3598)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg55_5"
                     /sec_met_domain="Glyoxalase_4 (E-value: 3e-26, bitscore:
                     80.6, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQQIDHIGIAVKSLDATVPYYRDALGLGEPHIEEVPTQKVRVAM
                     FDVAGVHIELLEPTSPESAIAKAIEKKGEGIHHIAFKTNDIAGNISQAKEAGLTVLNDP
                     PVPGAHNTQVTFLHPKCTFGVLTEFCQHPGGCECGK"
     CDS             3765..4130
                     /locus_tag="ctg55_6"
                     /transl_table=11
                     /translation="MFKSGLAVLFLLASWFSAACAYELLPAHVAVVYNGKSELSRRMAR
                     EYARVRGVPEGNLVSLDCPMTGEISRKEYEETIRVPLLETARKQRWWTPSGIASSPLMN
                     RKIFVLALMADLPMKIRH"
ORIGIN
        1 aggaagaccg gctcattgcc gttgtcctcc gtcacgttct ggaagtcctt caggttggga
       61 tccaccgtca gactgtcgtc tcccaggcgg gcggcgtcag ctttggcttt ttcctgggat
      121 tcccgcacgg acttgatttt ggaaacggtc agctggctgc cgggataaac ctgcatgggc
      181 tgctgcatgg tttccagata ctgggcgctg gcttccggcg tggtcagatt ggccggcacc
      241 ttggcgggcg tctgctgcag aggagccaca tgaacgcgca ggtagcccac gttgttcagg
      301 gacgtggagg ttacttcccc ctgttcattg gaggagatga cctgctggtt cagctgggtg
      361 atgagcattc cgttgtccgg aatgttggcg atgagggcgc cgaaagcaat gggaaccatc
      421 aggagaggtt cgtattgctt ggctacaccc agatacagga gcaggatggc aatgccccac
      481 atccctacca tttgccatga tagggagaag atgcccatcc cctgtaaaaa ggtgattaat
      541 gaatcaaaaa gactcatacg gaatgttatt gtagcggttt gttatctgag tcggagccag
      601 gaactgttgg aggttccggg cggttgccgc cgggattaac caattttggc cagagcctgt
      661 ccttcctgaa ccgtatcacc cgggtttacg cagaaagcgg tgagcgtgcc ggaggcggga
      721 gcgtagatga tggtattcat cttcatggct tccagcgtca gaatctggtc gccggccttc
      781 acggaggcgc cagcggccac gtccagggaa acaaccttgc cggcaagcgg gctgggcacg
      841 tctccggcgc cggcggcggc cggagcgggc gcaggtgcgg gagccggagc cggggcggcc
      901 acgggtgcgg atgcggcagg agcgggagcg gccacaggtg cgggggccgg ggctgcggta
      961 gtggaggata cctggtccag gagttctacg gatacgtcaa ataccttgcc gtctacggtg
     1021 atgcgaagtt tcttcatgat aatgtatggt atggagtatt aagttaaatg gttcccgccg
     1081 gggcgggggt aagggtgaat aatgctgtag ttcaacggga aggccgaatg cggtgggagg
     1141 cgaagatttc cgccctgcct gcggccgcat agccggagcc cggggattgc ttgatttcca
     1201 caatgcggtg gctcatgccg tccaggcccg cgtccacggc ggcggagatg acggccacca
     1261 tttccggcgt gagctccgtc atggcggagt ccaccgctgc ggagaggatg gcgagcattt
     1321 ccggcgtcat gcccggtttg cccgccgcag cgggggcggc ggcaggcgcg gccacgggag
     1381 cggcggtttt ggctttagcc ctgttctgaa tggcggcggc gatggagccg ctgatggtca
     1441 gaatgacggc caggccaccc aggcacatca tgaccaccat aatgccgaca atctgatagt
     1501 tcagattgtt catgacgttg gcgatgccct gtgcaaaggc gagtgttgtg agtaacatat
     1561 gatccgttga gatggatgtt agagcggaat gttgccgtgt ttcttggccg ggcgcacttc
     1621 cttcttgttc agcagggtgc gcagggcgaa ggcgattttg gcgcgggttt cttccggatt
     1681 gatgacttcc gtgatctgcc ccatgccggc cgccacatac gggttgtaga aggcttcccg
     1741 gtattcttca aggagttctc cctggcgttt ggctttttcc gccgggtctt ccacagcctt
     1801 caattcacgg ccgtagagca ccggaacggc gccttccgcg cccatgacgg cgatttccgc
     1861 gccgggccag gcgaagacgg cgtcagcgcc caggtccttg cagcacatgg cgatgtaggc
     1921 gccgccgtag gctttccgca tgatcagggt gactttgggc accgtggcct gggaataggc
     1981 gaagatgagt ttggcgccgt ggcggataat gccgccccgt tcctgattct tgccgggcag
     2041 gaagccgggc acgtccacca ggttcaccaa cggaatattg aacgcgttgc agaagcggat
     2101 gaagcgcgcg gccttgtcgg aggagtcgat atccaggcag ccggctttca cgttgggctg
     2161 gttggcgatg atgccgacta ctacgccgca gatgcggccg aagccgacga cgacattttt
     2221 ggcgaagtcc ttatgcactt ccaggaagtc cccgttgtcc accaggcggc tgatgatggg
     2281 ctggacgtcc agcggcgtgc ggttgtcgcc gggaatcagg tcgctcatgc cttcgtctgc
     2341 gctcaggtca agcggggtat ccagtttgtg gggcggttct tccgtgttgt tggaaggaag
     2401 gaaggaaagc agcctcttca ggatgtccat ggcgtgcgcg tcgctgtccg ctacgaaatg
     2461 gacgttgccg gacacggtgg cgtgaatggc ggcggagccg atgtcgtcca tcgtgcattt
     2521 ttcatacgtg acctgttcaa tcaccttggg gccggtgatg tacatgccgg cgttgccgga
     2581 attgcgcatg atgatgaagt ccgtcagggc gggggagtag gccgcgccgc ccgcgcaggg
     2641 acccagaatc atggagattt gcggaaccac gccggaggca agcacattgt tgtagaacac
     2701 ctgggcatag ccggaaaggg ccgccacgcc ttcctggagg cgcgcgccgc cggagtcgtt
     2761 cacggtcacc atcgggatgc cggctttcag ggcgtacttc tgggcatccg caattttcat
     2821 ggcgtgcatg tagccgaggg acccgccctg ggccaggaag tcggaggccg cgcaggccac
     2881 cggacggccg tccaccaggc cgaagccgga aacgacgccg tcgccgggga tttccttctt
     2941 gcccatgccg aagttgtggc agttgtggcg cacatgcatg ccgatttccg agaaggtgcc
     3001 ttcctcaaag aggtacccca tgcggtcgcg ggctgtcatt tcgccctttt catgtctctt
     3061 gtcgatcttt tcctgaccgc cgctgaggat taccttcttg cggcggctgt tcagatcgtc
     3121 aatcaatttg ggatcaatag ccattggtat agtggtatgg tgaataggga gaatgttact
     3181 tgccgcattc gcagccgccg gggtgctggc agaattcggt caggacgccg aaggtgcatt
     3241 tgggatgcag gaaggtgacc tgcgtgttgt gggcgccggg gacgggcggg tcgttcagca
     3301 cggtaaggcc cgcttccttg gcctgggaga tatttccggc gatgtcattg gtcttgaaag
     3361 cgatgtggtg gatgccttcc ccttttttct caatagcctt ggcgatagcg ctttccggag
     3421 aggtgggttc gagcagttcg atgtggacgc cggcaacgtc aaacatggcg acgcggacct
     3481 tttgagtggg gacttcctca atgtggggct cgccgagccc gagcgcatcg cggtaatagg
     3541 gaacggtggc gtcaagactc ttgacggcga tgccgatatg gtcaatttgc tgaatcatat
     3601 gcgtgtgatg gttatagggg aatgcagggg ggaggcctgc aatacatcaa gagttattaa
     3661 agcggatttt tttaagatgt gaagcgaaaa gcggaaaaat ggcgaattcg tggccggcct
     3721 tttcacctgc ttgattgccc cggaagatga ggtatggtag gggcatgttc aagagtggat
     3781 tagccgtgtt atttctgctg gcgtcatggt tttccgccgc gtgtgcctat gagctgctgc
     3841 ccgctcatgt ggccgtggtt tataacggaa aatccgagct gagccgccgc atggccaggg
     3901 aatatgcgcg ggtgcgcggc gttccggaag ggaatctcgt ttccctggat tgccccatga
     3961 ccggcgagat ttcgcggaag gagtatgagg agacgatccg cgtcccgctg ctggagacgg
     4021 cgcggaaaca acggtggtgg acgccttccg gcattgcgtc ctcccccttg atgaaccgga
     4081 agatttttgt gctggcgctg atggcggacc tgccgatgaa gatacggcat
//
