LOCUS       gnlProkkaGCMHFKML_26   12366 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GCMHFKML_26.
ACCESSION   gnlProkkaGCMHFKML_26
VERSION     gnlProkkaGCMHFKML_26
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-02 02:30:46
            Original ID  :: gnl|Prokka|GCMHFKML_26
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12366
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12366
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2012:2366]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2013..2366
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12366
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12366
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             83..448
                     /locus_tag="ctg26_1"
                     /transl_table=11
                     /translation="MLIASVLMCFIVLIQNSKGGGLASGFSSSNQIMGVRKTTDFLEKA
                     TWTLAAVMVVFSIVSAYTIPSSTGKGGDVILEQAQQEEKTNPYNMPVGTEAPQSEAPAA
                     TTPAETPAPAAEAPAAE"
     CDS             602..1993
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 102; E-value: 4.6e-31)"
                     /gene_kind="transport"
                     /locus_tag="ctg26_2"
                     /transl_table=11
                     /translation="MTEQLKLKLNDSKATRWGALVIVAFTMMVAYYVNDVVAPLKTMLE
                     TDLAWSSTDFGFFTGGYSFLNVFFLMLIWGGLILDRFGIRFTGKLATILMVGGTALEYY
                     AMTGLAGADATLFGINEIFGYKTGVFVAFAGYSIFGVGAEVAGITVSKIIAKWFKGKEL
                     ATAMGVQVALARIGSQAGYAVAIPLARAFGISTPVLLGLVLLLGGMIAFFIFAVMDKKL
                     DKQMEAAAIAAGTEDEEEKFSFKDVKNILVNPGFWLIALLCVLFYSCVFPFQKFASELM
                     IIKYGINENVAGTFAGLPALGALILTPVFGGFIDKRGKSASIMLLGSAMLICVHFIYAI
                     PDINYWLVAIVLMIILGIAFSLVPSAMWPAVAKIFPVSQLGTAYALIFFIQNIGLWGIP
                     TLIGWVLDAYCISGKKPDGTNMYDYTVPMCIFTGIACLSLIVALLLKKADKKYGYKLEE
                     PNIQK"
     CDS             2013..2366
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg26_3"
                     /sec_met_domain="PqqD_RRE (E-value: 3.8e-10, bitscore:
                     30.9, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 6.8e-17, bitscore: 53.1,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMEIPEGKVSLLDAVPVRCGHITTEWEGECAVLAYPRFKYEWMRR
                     FLLPKGMSPDIHVRLEEHGTAVWNLIDGHRTVREIISLLARHFGEEENYIPRVTAYVMQ
                     LRKDGFIQLTIRN"
     CDS             complement(2374..3432)
                     /locus_tag="ctg26_4"
                     /transl_table=11
                     /translation="MYIMKKNILMLSALFLSITAMAQTDVTTGVMRGKDYGVTYMLPKT
                     EIEIVLQATKHTYTPGEFCRYADRYLRLNNVSAEPEEFWTLDKIETRIAGVPDKDNVYF
                     VKMKDKTVAPLMELTEDGIVRSINIPFSGKPAAKTPEAKATESSIDPRSFLTEEILMSN
                     SSAKMAELVAKEIYSIRESKNALLRGEADNMPKDGAQLKLMLDNLNQQETAMTEMFSGK
                     IKKEPKTFTIRLTPKEMKDEVAFRFSRKLGVVANNDLAGEPYYISVTDLKSPDVSATEE
                     GKKKVDGVAYNLPGKAQVTLMYNNKKLFDDQLPITQFGTVEYLAPVLFNKNSTIKVLFD
                     TATGGLIKVDRE"
     CDS             complement(3494..4621)
                     /locus_tag="ctg26_5"
                     /transl_table=11
                     /translation="MKTLLFCMLGLGLTACGSSPKGTNGDQDELAMLIGTYTNGSSKGI
                     YTFRFNQETGTAVPLSSAALPNPSYLVPSEDGEFVYAVSEMNDSTAALSSLAFDRETGE
                     LRLLNTVPTFGADPCYVATNGREVLTANYSGGTMSVFPLQKDGTLAPADTLFQGSATGP
                     DAIRQATPHIHCTVFSPDGKYIFATDFSADRILRFVMHPDDPIPHASLEAVDIEADSGP
                     RHLTFSPNGKFAYLITELSGKVIAFSYDDGCLEQIQTITADTVAARGSADIHLSPDGKY
                     LYASNRLKEDGIAIFAVNPENGTLAKVGYQPTGIHPRNFNITPNGKYLLAACRDSNVIQ
                     VYKRNEVTGLLEDTHQDIVVDMPVCVQFVSSVNNL"
     CDS             complement(4723..5877)
                     /locus_tag="ctg26_6"
                     /transl_table=11
                     /translation="MGGGQRTCGENKSRTSLDLPGRQLQLLQAIQATGKPVVLILINGR
                     PLSINWADKFVPAILEAWYPGSKGGTALADILFGDYNPGGKLTVTFPKTVGQIPFNFPC
                     KPSSQIDGGKNPGPTGNMSRINGALYPFGYGLSYTTFEYSDLDITPRVITPNESATVRL
                     KVTNTGKRAGDEVVQLYIRDVLSSITTYEKNLAGFQRIHLEPGEAQELSFTIDRKHLEL
                     LDADMKWVVEPGDFVLMAGASSEDIRLNGTLTVEDYQTRAKAIEAQKPAKRVSASTNPE
                     DAENVLDEKINTAWQGNKGDYITFALKNGAKVDKVAIAFTRDNNLPATFEIQLSGGGGQ
                     FLTVYSGTVSEYGKLISYPFKGTTASDLRIVLNDDRVSIAEVKF"
     CDS             complement(5894..7699)
                     /locus_tag="ctg26_7"
                     /transl_table=11
                     /translation="MEDIFSKRKTLRTIKADTSDYFIPLFHTLAVFLSTKETIITKRFL
                     EHIMKNLIALTLLLGGSTLLCAQKPAKTPATYKPVKSEMYRKGWIDFNKNGVKDXXXXX
                     XXXXXXIENLLQQMTLDEKTCQMVTLYGYKRVLKDDLPTPEWKELLWKDGIGAIDEHLN
                     GFQQWGLPPSDNAYVWPASRHAWALNEVQRFFVEDTRLGIPVDFTNEGIRGVESYRATN
                     FPTQLGLGHTWNRELIRQVGLITGREARMLGYTNVYAPILDVGRDQRWGRYEEVYGESP
                     YLVAELGIEMVRGLQHNHQVAATGKHFAAYSNNKGAREGMARVDPQMSPREVENIHIYP
                     FKRVIREAGMLGVMSSYNDYDGIPVQGSYYWLTTRLRGEMGFRGYVVSDSDAVEYLYTK
                     HGTAKDMKEAVRQSVEAGLNVRCTFRSPDSFVLPLRELVKEGGLSEEVINDRVRDILRV
                     KFLIGLFDAPYQTDLADADREVEKEENEAIALQASRESIVLLKNAGELLPLDINSTKKI
                     AVCGPNANEEGYALTHYGPLAVEVTTVLEGIQEKTKGKAEVLYTKGCDLVDAHWPESEI
                     IDYPLTDDEQAEIDKAVEXXXXPSS"
     CDS             7841..8014
                     /locus_tag="ctg26_8"
                     /transl_table=11
                     /translation="MYLYNRNLLAELLLVRKNFLFNLGMSKPNLGLDIPRLGMKKPKFG
                     IDCFLNSFRFFS"
     CDS             8052..8210
                     /locus_tag="ctg26_9"
                     /transl_table=11
                     /translation="MQISITEDRYSLLQGVIPSTDTGFGSCLNIDDNGVHIFYVWKIIV
                     FITKSQY"
     CDS             complement(9166..9399)
                     /locus_tag="ctg26_10"
                     /transl_table=11
                     /translation="MGDRPSRGRSFDFNSLTLVHLRNINQLTSMGFVIAKTDIIVFPYY
                     QLYRFTLREMSRTNRAIHFYIYHKTKSGCYLR"
     CDS             complement(9665..10495)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 55.5; E-value:
                     9.7e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg26_11"
                     /transl_table=11
                     /translation="MDNQTQEGTKNMQKRHTDRESYFDEQSQTSKNYYIPYIKEVIGHI
                     PDKVLEVGCGEGGNLLPFAKAGCRVMGVDIDAMRIEQARTFFTQRHQQGQFIATDIFQL
                     KDKATNFPLILLHDVIEHIRDKERFLSGLQKHLSADGAVFVGFPAWQMPFGGHQQIAHS
                     HIVSHFPFLHLLPRTLYRWILRLCGEQERVITELLDIKSTGCTIELFNRIVRQANYQII
                     DRRLYLINPHYKIKFGLSPRRLNGVIAAIPYIRNFFCTSCFYILKKGTKTVNHY"
     CDS             complement(10544..11404)
                     /locus_tag="ctg26_12"
                     /transl_table=11
                     /translation="MKDSIHKYPIPSPFTGQTITNRQMAFASSPSLMPPTRKKKSRKWK
                     LMLAGSLGPQLAQNLYKLIATPHTDGISSDFPQQVSTWEEYYSYLHTRYQQGTLGKDSI
                     GLMQIAQNNSGRIVENQQHHAPIVVGLSLSKKLNERWSLETGLQYTLLRSEFTTGEAFR
                     IQDNQKLHYIGIPLRLSYRFWHYKRFSSYATAGMQVDIPIKGTLQSFHVTDSIPHKLDS
                     QPVSAPWQWSVNTSIGIQYHLTPQAGIYLEPTVNYYIPDGSQLRTIRKEHPFTFTLPVG
                     LRISW"
     CDS             complement(11610..12143)
                     /gene_functions="regulatory (smcogs) SMCOG1032:RNA
                     polymerase, sigma-24 subunit, ECF subfamily (Score: 69.8;
                     E-value: 3.8e-21)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg26_13"
                     /transl_table=11
                     /translation="MSLLYENYSEKMLKVCLRYIPDPTIAQDLLHDGFVIIFTSIHSLR
                     NPEKLEYWMKKIMRNLALQYLNHANANPTIPLTDIPEEEEPAENPFCPDFISYDKMLDI
                     VESLPEGYCKVFKLAVLEGLSHKEIGDLLGIAPHSSSSQLFRAKILLKKMLAGYRVFIV
                     LTVLLLFPTLXXXX"
ORIGIN
        1 gcagaccaaa tcagattttt ggagaaattg attattaacg ctaaatcaaa ataacaaaat
       61 gtatttatta ttagttatct taatgctgat tgcatctgtg ctgatgtgct tcattgtatt
      121 gattcaaaat tctaaaggag gtggtctggc atcaggcttt tcatcatcca accaaattat
      181 gggtgtgcgc aagactacgg actttttgga aaaagcaacc tggactctgg cagctgtcat
      241 ggtagtcttc agtattgttt ctgcttacac tattccttct tccacaggca agggcggtga
      301 tgtgattctg gaacaggcgc aacaagaaga aaaaactaat ccttataaca tgcccgtagg
      361 tacagaagct ccgcaatcgg aggcccctgc agctacaact ccggctgaaa ctcctgctcc
      421 tgcagcagaa gcccctgcag cagaataaga taaggatatt gcggatgact cccgcttgga
      481 aaaataagag aaaggttgat actgaaaagg tgtcagcctt ttttcgtttt gatgaagtat
      541 ttatttacct ttgtcagcaa tttatgcaat ctgattaata aattgaaatc caaatagtac
      601 aatgacagaa caactcaaac ttaaattgaa tgattccaag gctacccgtt ggggggcatt
      661 ggtgattgtt gccttcacga tgatggtagc ttattatgta aacgacgtgg tagcaccgtt
      721 gaagacaatg ttggaaacgg acttggcttg gtcgagtacc gatttcggat tctttaccgg
      781 tggttatagt tttctgaatg tttttttcct gatgttgatt tggggaggat taatcctcga
      841 ccgctttggt atccgtttca ccggaaagct ggcaactatc ctgatggtag gtggtacagc
      901 acttgaatac tatgcaatga cgggacttgc cggtgccgac gcgactttat tcggaatcaa
      961 tgaaatattt ggctataaaa cgggtgtgtt tgttgctttt gccggttatt ccatttttgg
     1021 agtaggagcg gaggtcgccg gtattacagt ttccaaaatc atagccaagt ggtttaaggg
     1081 gaaagagctt gccacggcta tgggggtaca agtcgcttta gcacgtatcg gttcgcaagc
     1141 cggttatgcc gtagccattc ctttggcccg cgctttcggt atttccacac cggtgttgtt
     1201 gggtttggtt ctgttgttgg gcggtatgat tgctttcttc atctttgcag tgatggacaa
     1261 gaagctggac aaacagatgg aagctgctgc cattgctgcc ggtacggaag atgaggaaga
     1321 gaagttctct tttaaggatg tgaagaatat tctggtcaat cccggtttct ggctgatagc
     1381 attgctgtgt gtattgttct actcttgtgt attcccattc cagaagtttg cttccgagtt
     1441 gatgattatc aaatacggta tcaatgagaa tgtggccggt acatttgccg gacttccggc
     1501 attgggagcg ctgattctga ctccggtctt tggtggtttc attgacaagc ggggcaagtc
     1561 cgcatctatc atgctgctgg gctcggccat gctgatatgt gtgcatttca tttatgctat
     1621 tcccgatata aactattggc tggtagctat tgtgctgatg ataattttgg gtatcgcttt
     1681 ctcgctggta ccttctgcca tgtggccggc tgtggccaag atattcccgg taagccagtt
     1741 gggtacggca tacgcattga ttttctttat ccagaatatc ggtctttggg gtattcctac
     1801 attgataggg tgggtgcttg atgcctattg tatatccggc aagaaaccag atggaacgaa
     1861 tatgtatgac tatacggtgc ctatgtgcat ttttaccggt attgcctgct tgtcccttat
     1921 agtggctcta ctgctgaaga aggcagacaa gaagtatggt tataagctgg aagagcctaa
     1981 tattcagaaa taataggaaa agcggatacc gtatgatgga aatacccgaa ggaaaagtaa
     2041 gtctgttgga cgctgttccg gtccgctgtg gacatataac aaccgaatgg gaaggtgagt
     2101 gcgccgtact cgcctaccca cggtttaaat acgaatggat gcgtcgtttt ttattgccga
     2161 aggggatgtc tcctgacatc catgtgaggc tggaagaaca cggtacagct gtctggaatc
     2221 tgatagatgg acatcgtacc gtgcgcgaaa tcatctctct acttgccagg cactttgggg
     2281 aggaagagaa ttatattccc cgggtcaccg cctacgtaat gcagttgcgt aaggatggat
     2341 ttatccagtt gacaatccgg aattagaatt cctttattcc ctatctactt ttatcaatcc
     2401 tcccgttgcc gtatcaaaca gcactttgat ggtagaattc ttgttgaaca gtaccggtgc
     2461 gaggtattct acggtgccga attgggtaat gggaagttgg tcgtcaaaca atttcttatt
     2521 gttatacatc aatgtcactt gtgccttgcc cggaaggtta taggctacac cgtccacttt
     2581 ctttttgcct tcctcggtgg cagatacatc gggacttttg aggtcggtga cgctgatata
     2641 atacggttca ccggcaaggt cattattggc caccactccc agcttccggg aaaaacggaa
     2701 agccacctca tctttcatct ctttaggcgt cagccggatg gtgaatgtct tgggttcttt
     2761 ctttattttg cccgagaaca tttccgtcat agccgtttcc tgctggttca gattgtcaag
     2821 catcagcttg agttgggcgc cgtccttggg catattgtct gcttcgccgc gcaggagggc
     2881 attcttgctt tcgcggatgc tgtatatttc cttggccacc agctcggcca tcttggcact
     2941 ggagttggac atcagtattt cttccgtcag aaaactgcgt gggtcaatgc tgctttcggt
     3001 ggctttggct tcgggcgtct tggcagcagg cttaccgctg aacggaatgt tgatggagcg
     3061 gacaattccg tcttcggtaa gctccataag gggtgctacg gtcttgtctt tcatcttcac
     3121 gaaatagacg ttgtccttat ccggtacacc ggctatgcgg gtttctatct tatccagtgt
     3181 ccagaactcc tcgggttcgg cagacacgtt gttgagacgc agatagcggt cggcatatct
     3241 gcaaaattct ccgggagtgt aggtatgctt ggtggcttgc aatacgattt ctatttctgt
     3301 tttgggcaac atataagtca ctccgtagtc tttgccacgc atcacaccgg tggttacgtc
     3361 tgtttgcgcc atggcagtga tagacaagaa cagagctgag agcatcaata tattcttctt
     3421 cataatgtac attcgtttag actgatttag ctaagggaca aagttaatga agttatcttt
     3481 gctaaatatt gctttataaa ttattaacag agctgacgaa ctgtacgcaa accggcatgt
     3541 cgactacaat gtcctgatga gtatcttcca agagtccggt aacttcgttt cgtttgtata
     3601 cctgaatgac attgctgtcg cggcaggcgg caagcaagta tttgccgttg ggcgtgatgt
     3661 tgaagttgcg gggatggatg ccggtgggct gataacctac ctttgccaag gtcccatttt
     3721 cgggattcac ggcaaagatg gcgatgccgt cttctttcag acggttgctg gcgtagaggt
     3781 atttcccatc cggactgagg tggatgtctg cacttccacg ggcggctacg gtgtcggctg
     3841 tgatagtctg tatctgttcc aggcagccgt cgtcgtaact gaaggcaatg accttaccgg
     3901 acagttcggt gatgagatag gcaaacttcc cgttagggct gaatgtcaga tggcgcgggc
     3961 cggaatccgc ttcaatgtca acggcttcca gagaagcatg aggaataggg tcgtcggggt
     4021 gcatcacaaa gcgcaggatg cggtcggcac tgaagtcggt ggcaaagatg tattttccgt
     4081 ccggtgaaaa gaccgtgcaa tggatgtggg gagtggcttg ccgtatggcg tcgggaccgg
     4141 tggcagagcc ttgaaagagc gtgtctgcag gagccaaagt gccgtctttc tgtaaaggaa
     4201 agacggacat ggttccaccg ctgtagttgg cagtcaacac ttcccggcca ttggtggcca
     4261 cgtagcaggg gtcggcgccg aaggtgggaa cggtgttcag caggcgcagt tctcccgttt
     4321 cccggtcgaa ggcaagggag ctgagggctg ctgtgctgtc gttcatttca ctgacggcat
     4381 agacaaattc gccatcttcc gaggggacga ggtaggaggg attgggcaat gccgctgaac
     4441 tgagcggaac ggctgttccc gtctcctgat taaagcggaa ggtatagata cccttgcttg
     4501 agccattcgt gtaagtacct attagcatgg cgagttcgtc ctggtcaccg ttagtgccct
     4561 ttggagaaga gccacatgct gtcaaaccta atccgagcat acagaaaaga agtgttttca
     4621 ttaatttaat gtgttaatgt gccaatatgc taatgtgcta attggctgcg ctgtatatgc
     4681 tgcatggtca ttggtacatt agcatattgg cacattagca cattaaaatt taacttcggc
     4741 aatactgacg cggtcatcgt tcagcacgat gcggaggtcg ctggcggtag tgcctttgaa
     4801 cggataggaa atcagtttgc cgtattcgct gacggtgccc gaatatacgg tgaggaactg
     4861 tccgccaccg cccgagagct ggatttcgaa ggttgccggc aggttgttgt cacgtgtaaa
     4921 ggcaatggca actttatcta ccttggctcc gttctttaag gcaaaggtaa tataatctcc
     4981 cttatttcct tgccatgcgg tattgatttt ttcgtcgagc acgttttcgg catcctctgg
     5041 gttggtgctg gcactcacac gctttgctgg tttttgggct tcaatggctt tggcacgggt
     5101 ctggtagtct tctacggtca gcgttccgtt caggcggatg tcttcggaag aggcgccggc
     5161 catgagcacg aagtcgccgg gttccaccac ccatttcatg tcagcgtcca gaagctccag
     5221 gtgcttgcgg tcgatggtga aggacagctc ctgggcttcg cccggttcga ggtggatgcg
     5281 ctggaagcct gcaagattct tttcgtaggt ggtgatgctg ctcagtacgt cgcggatata
     5341 gagctgcact acttcatctc cggcacgttt gccggtgttg gtcaccttca ggcggacggt
     5401 ggcagactcg ttcggggtga tgactcgggg ggtgatgtcg aggtcggagt actcgaaggt
     5461 ggtgtagctc aagccgtaac cgaaggggta gagtgctccg ttgatgcgtg acatgttgcc
     5521 cgtaggtccc ggattcttac cgccgtctat ctgtgaagaa ggtttgcagg ggaagttgaa
     5581 ggggatttgc cctacggtct tggggaaggt caccgtcagc tttccaccgg ggttgtagtc
     5641 gccgaagagg atgtcggcca gggctgttcc gcctttggag ccgggatacc aggcttcgag
     5701 gatagcgggg acgaacttgt ctgcccagtt gatggagagc gggcgtccgt tgatgagtat
     5761 cagtacgacg ggcttgcccg tggcttgtat ggcttgaagc agttgcaact gccgaccggg
     5821 caggtcgagg ctggtgcgcg atttgttttc gccgcaggtg cgttgtccgc cgcccaatac
     5881 tacgacggca acatcagctt gacgggnnnn nnnnnntttc tacggctttg tctatctcgg
     5941 cttgttcgtc gtcggtcagc ggatagtcta tgatttcact ttcgggccag tgggcgtcca
     6001 ccaggtcgca gcctttggtg tagagcacct ctgccttgcc ttttgtcttt tcttgaatgc
     6061 cttccagcac agtggtcact tctacggcaa gtgggccgta atgggtcagc gcgtagcctt
     6121 cttcattggc attgggacca cagacggcaa tcttcttggt ggagttgatg tctaagggca
     6181 atagttcacc ggcattcttc agcagaacga tggactcgcg ggatgcctgc aaggcaatgg
     6241 cttcgttctc ttctttttcc acttcacggt cggcatcggc aaggtctgtc tgataggggg
     6301 catcgaacag accgatgagg aactttaccc gaaggatgtc gcgcacgcgg tcgttgatga
     6361 cttcttcgct cagtccgcct tccttcacca gttcgcggag gggaaggacg aaggagtcgg
     6421 gcgagcggaa ggtgcagcgt acgttcagtc cggcttccac gctttggcgg acggcttctt
     6481 tcatgtcttt ggcggtgccg tgcttggtgt agaggtattc tacggcgtca ctgtcggata
     6541 cgacgtagcc acggaatccc atttcgccac gcaggcgggt ggtgagccag tagtagctgc
     6601 cctgcacggg gatgccgtcg taatcgttgt acgaactcat tacgcccagc atgccagctt
     6661 cccggatgac gcgtttgaag gggtagatgt gtatgttttc cacttcgcgc ggcgacattt
     6721 gcgggtccac gcgtgccatg ccttcgcggg cgcctttgtt gttactgtaa gcggcaaagt
     6781 gcttgccggt ggcggccact tggtggttgt gctgcaagcc gcgcaccatt tcgatgccca
     6841 gttcggctac gaggtaggga gattcgccgt aaacttcttc gtagcgtccc cagcgctggt
     6901 cgcgtcctac gtcgaggatg ggggcgtaga cgttggtgta gcccagcatg cgggcttcgc
     6961 gtccggtgat gagtcctact tggcgaatca gttcacggtt ccaggtatgt cccagtccca
     7021 gttgggtggg gaagttggtg gcgcggtagc tttccacgcc gcgtatgcct tcgttggtaa
     7081 agtctacggg gataccgaga cgggtatctt ccacaaagaa ccgttgcacc tcgttcagtg
     7141 cccaggcgtg gcgcgaggcg ggccagacgt aggcattgtc cgagggaggc agcccccatt
     7201 gctggaagcc gtttaggtgt tcgtcgatgg cgccgatacc gtctttccag agcagctctt
     7261 tccattcggg ggtggggagg tcgtctttca gtacacgttt gtaaccgtag agggtgacca
     7321 tttggcaggt cttttcgtcc agcgtcatct gttgcagcag gttttcgatg nnnnnnnnnn
     7381 nnnnnnnnnn nnnnnnnnnn ncgtctttca ctccgttttt gttgaagtct atccaacctt
     7441 tgcggtacat ttcacttttc accggcttgt aggttgccgg tgttttggca ggcttttgtg
     7501 cgcagagcag tgtgcttcct ccaagcagca gggttagggc aataaggttc ttcatgatat
     7561 gttctaaaaa tctcttggtt attattgttt cttttgttga caaaaatacg gctaatgtgt
     7621 gaaataaagg gataaaatag tccgaagtat cggcttttat tgtccgaagg gtcttcctct
     7681 tactaaaaat atcctccaag acgctaccgg ggaattcaaa tcattattag acgaaacata
     7741 tcattcactt ttaaaaagaa agagagaaca ctataataac ctgaaaagta gatgcaatcg
     7801 cggtgtatac aagtattacg gctacatctg ttaaacgagg gtgtatttat ataataggaa
     7861 tctgttggcg gaattgttgc ttgtacggaa gaactttctt ttcaaccttg ggatgtctaa
     7921 accaaacctt ggtttagaca tcccaaggct gggtatgaaa aaaccaaagt ttgggataga
     7981 ttgcttcctt aattctttcc ggtttttcag ttaacttcag agactttttc cgttaatttc
     8041 ccatctcttt tgtgcaaata tccattacag aagatagata ttccctcttg cagggggtaa
     8101 ttccgtcaac ggatactggc tttggtagct gtttgaacat tgatgacaat ggggtgcaca
     8161 tattctatgt atggaagatt attgttttta tcacgaaaag tcagtattag ctaatatttg
     8221 taaatatatg gtgattgcta ataaaagaat atgtatcttt gggccaaaga aagcggtaga
     8281 ggatgaaaaa taaagtagca tttatccctt tttcaccctc cctacttagc aatgagttac
     8341 gcaatctttt aaatttcaga ccgttacaaa gtcatggggt tgactggatt tgacagcggg
     8401 cagaaatggt aagtaagcat gcagtgcgtc gttgatttgc actttaatct cagtcctcaa
     8461 aattttatct ggcgaaactc gttacgctct cgctgcttaa tcgaagtata gtagattgaa
     8521 gcttaatccc ggcaccaggt gctgggacgt gacatcactc ggaagctgtt gctccgaagc
     8581 attccgataa agtggtgcag tcaaatcggg gatagttcgt gtcagcctcg tggcgcgggt
     8641 gaaaatttag aggataaggc aacggttgat ggctttggtt ctgccgctgc acgaaaattt
     8701 aggcaaagat aagcatgtag aaagcttatg atttcctcgt ttggacgagg gttcgattcc
     8761 ctccagctcc acggatatag taaaaagaag tttgtaagtc cttgaattcc agtaattcag
     8821 gggctttttc ttttcttcta ctccccctac cttttatatt catttagaaa atagttgtag
     8881 taaatgtgct acaattcaaa attaatatct acttttgtct gttcaaaaat caataactat
     8941 tagaagtggg ggcaacactt taaattctgc aacagattta tgaaaattca cgaaggaaaa
     9001 tgtacagaga agattttgaa agaacgtgaa cggattggta gtcggttagc cattcttcgc
     9061 aagaagagaa atatgaccca agaggaattg gctaatcttt gtggtgttaa tcgtgttaat
     9121 atagccaaga tagagaaagg ggcttataat gtgagcattg atatactatc taaggtaaca
     9181 tccgctcttg gttttgtgat agatataaaa gtggatagct ctgtttgtcc gactcatttc
     9241 tctcaacgta aacctgtaaa gctggtaata gggaaagact attatgtcag ttttggcaat
     9301 aacgaagccc atagatgtaa gctggttgat attccggaga tgtaccaagg tcaaagaatt
     9361 aaaatcgaaa ctccgacccc gagagggtct atcacccaca tattatttgc cgatgaaata
     9421 ggaacgacac ctgacgaggc tgtaatgaac caagtaacga tgtaaaaaca ttaaaaggga
     9481 ggaagtgcaa gttcctcttt tattgaaatc accttcgcta caaccatctg cagcgagggg
     9541 gattttttag tttatgaggg tttctacacc cactctttca tcagagctat tcaaaaaatt
     9601 aatggtttct tctgaatata taatcttaaa ttgatggttc ggaatcaatt ctaaagctgg
     9661 gaaatcagta gtgattaaca gttttagtcc ctttctttaa tatgtaaaag caacttgtac
     9721 aaaagaagtt tcttatatac gggatagcag caataactcc gttgagcctt cgtggggaca
     9781 agccgaattt gattttataa tgtgggttta taaggtacag tctccggtca atgatttgat
     9841 agttggcttg ccggacgatg cgattgaaca gttcgatggt gcatccggtg ctctttatat
     9901 ccagtagctc cgtgattacg cgttcctgct caccgcatag tcttaatatc catctgtata
     9961 aagtgcgggg aaggaggtgg agaaaaggga aatgtgaaac aatgtggctg tgtgctatct
    10021 gctggtggcc tccgaatggc atttgccagg cgggaaaccc tacaaataca gctccgtcgg
    10081 cagacaaatg tttttgtagg ccggagagga accgttcttt gtctctgata tgctctatca
    10141 catcgtgtag aagaatcagg ggaaaattcg tagccttgtc cttaagctgg aaaatgtcgg
    10201 tggcaatgaa ctgtccctgc tgatgccttt gggtgaagaa ggtcctggct tgctctattc
    10261 gcatggcatc aatgtctacg cccatcaccc ggcaaccggc tttggcaaag ggaagcagat
    10321 tgcctccctc tccacagccc acttccagca ctttatcggg gatgtgtccg atgacttcct
    10381 ttatgtaggg gatataatag ttcttgctgg tctgtgactg ttcatcaaag tagctttccc
    10441 ggtcggtatg tcgtttctgc atgttctttg ttccttcttg agtttgatta tccatataaa
    10501 tagataatca gtcgggtaaa agactgcgtg gcgcatcgtt tttttaccag gaaatgcgga
    10561 ggcctaccgg gagggtgaat gtgaacgggt gttcctttcg gatggtgcgc agttggctgc
    10621 cgtcggggat ataatagttt acagtcggct ccagatagat gcctgcctgg ggtgtgaggt
    10681 gatattgtat gcctatactt gtgttgaccg accactgcca gggagcactt accggctggc
    10741 tgtcgagctt gtgtggaata ctgtctgtga catggaagct ttggagtgtc ccttttatgg
    10801 ggatatccac ctgcatgcct gccgtggcat aactggagaa acgtttgtaa tgccagaaac
    10861 ggtaggaaag ccggagagga atgccgatat aatgcaactt ctggttgtct tgaatgcgga
    10921 atgcttcgcc ggtagtgaac tccgacctga gaagcgtata ttgcaatccg gtttccagac
    10981 tccaacgctc attcaatttc ttgctgagag agagtcccac gacgatgggg gcatgatgtt
    11041 gctggttctc aacaatcctg ccgctgttat tctgggcaat ctgcatgagt ccgatggaat
    11101 cttttcccag agtaccctgc tgatagcggg tgtgcagata agaataatac tcttcccacg
    11161 tgctgacttg ttgagggaag tcacttgaaa tgccgtcggt atgtggagtg gcaatcagct
    11221 tatataagtt ctgtgccagt tgcggtccga gtgaacctgc cagcatcaac ttccatttcc
    11281 tggatttctt cttgcgggtt ggcggcatta gggaagggga ggaggcgaaa gccatctgcc
    11341 ggttggtgat ggtctgtccg gtgaatggag aaggtatggg atatttgtgg atgctatctt
    11401 tcattttggg tatggcaagg ggccattctg tggaaacagg aacgggaggg atgattcgtt
    11461 cccttttgtt cagattttct ttggtatggc attgttcgtc ggttcgggga gtatcggttt
    11521 tctttgtttg ttgcgtactc ccggcttgcc tggaagaaac tttggacaaa cggttttccc
    11581 tgatactctt tttctctctg tacagatagt cannnnnnnn nntatagcgt tggaaagaga
    11641 agcaatactg tcaaaacaat gaatacacgg tatcctgcca gcatcttttt aagtaaaatt
    11701 ttcgcccgga acaattggga ggaagaggag tgtggcgcta tacccagtaa atctccgatt
    11761 tctttgtggg acaatccttc cagtactgcc agtttaaata ccttgcagta gccctccgga
    11821 aggctctcca ctatatccag catcttatcg tacgaaatga aatccggaca aaaaggattt
    11881 tcagcaggct cttcctcttc cggaatatct gtcaatggga tggtggggtt ggcattggca
    11941 tggttgaggt attgcagtgc caggtttctc ataatctttt tcatccagta ttccagtttc
    12001 tccgggttgc gcagcgaatg aatggaagtg aatatgatga caaaaccgtc gtgaagaaga
    12061 tcttgggcta tcgttgggtc gggaatatag cgtaggcata ctttcagcat tttctctgaa
    12121 tagttttcgt agagcaggct caaggcctgc ccgtttccct tctggcataa agtgacaaga
    12181 gcttttgtat ccatgtgttt gtctcaatgt tatttcttaa ggatagagaa gaacatgaat
    12241 gactgcatgg atttttattt tttaactaag cctcccggtt gacttctgct gcacagtccg
    12301 gacaaatgcc tttcagtaca tagttgatgc tgttcagcgt aaatccttga ggcagcttca
    12361 ccaccg
//
